nicotine has been researched along with acetaminophen in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.17) | 18.2507 |
| 2000's | 10 (41.67) | 29.6817 |
| 2010's | 12 (50.00) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Rudolph, AM | 1 |
| Baranovski, VY; Dimitrov, M; Dosseva, V; Lambov, N; Shenkov, S | 1 |
| Apinan, R; Choemung, A; Na-Bangchang, K | 1 |
| Afzali, P; Akkara, J; Alfi, DM; Conell-Price, J; Eisig, SB; Flood, P; Olson, L; Yagoubian, B; Yeh, J | 1 |
| Boleda, MA; Galceran, MA; Ventura, F | 1 |
| Bohrn, U; Fleischer, M; Kubisch, R; Stütz, E | 1 |
| Burgoon, LD; Johnstone, AF; Lin, BJ; Mack, CM; Shafer, TJ; Turner, JD | 1 |
| Lee, G; Mundstock, A | 1 |
| Engelhard, C; Heide, M | 1 |
1 review(s) available for nicotine and acetaminophen
| Article | Year |
|---|---|
Pharmacodynamics in the maternal-fetal-placental unit.
Topics: Acetaminophen; Amniotic Fluid; Animals; Biological Transport; Female; Fetus; Humans; Nicotine; Placenta; Pregnancy | 1995 |
1 trial(s) available for nicotine and acetaminophen
| Article | Year |
|---|---|
Nicotine nasal spray as an adjuvant analgesic for third molar surgery.
Topics: Acetaminophen; Administration, Intranasal; Adolescent; Adult; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Blood Pressure; Cross-Over Studies; Double-Blind Method; Female; Follow-Up Studies; Ganglionic Stimulants; Heart Rate; Humans; Hydrocodone; Male; Middle Aged; Molar, Third; Nicotine; Pain, Postoperative; Placebos; Postoperative Nausea and Vomiting; Premedication; Prospective Studies; Treatment Outcome; Young Adult | 2011 |
22 other study(ies) available for nicotine and acetaminophen
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Hydrogels based on the chemically crosslinked polyacrylic acid: biopharmaceutical characterization.
Topics: Acetaminophen; Acrylic Resins; Biopharmaceutics; Cross-Linking Reagents; Delayed-Action Preparations; Hydrogels; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Isocyanates; Molecular Structure; Molecular Weight; Nicotine; Technology, Pharmaceutical | 2003 |
A sensitive HPLC-ESI-MS-MS method for the determination of cotinine in urine.
Topics: Acetaminophen; Adult; Chromatography, High Pressure Liquid; Cotinine; Drug Stability; Female; Humans; Linear Models; Male; Middle Aged; Nicotine; Polymethacrylic Acids; Polyvinyls; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tobacco Use Cessation Devices | 2010 |
Behavior of pharmaceuticals and drugs of abuse in a drinking water treatment plant (DWTP) using combined conventional and ultrafiltration and reverse osmosis (UF/RO) treatments.
Topics: Acetaminophen; Caffeine; Cocaine; Cotinine; Environmental Monitoring; Erythromycin; Halogenation; Illicit Drugs; Iohexol; Kinetics; Nicotine; Osmosis; Ozone; Pharmaceutical Preparations; Ultrafiltration; Water Pollutants, Chemical; Water Pollution, Chemical; Water Purification; Water Supply | 2011 |
Cell-based sensor system using L6 cells for broad band continuous pollutant monitoring in aquatic environments.
Topics: Acetaminophen; Animals; Cell Line; Copper Sulfate; Cricetinae; Drinking Water; Electric Impedance; Environmental Monitoring; Hep G2 Cells; HT29 Cells; Humans; Nickel; Nicotine; Rats; Water Pollutants, Chemical | 2012 |
Burst and principal components analyses of MEA data for 16 chemicals describe at least three effects classes.
Topics: Acetaminophen; Action Potentials; Animals; Cells, Cultured; Cerebral Cortex; Data Interpretation, Statistical; Fluoxetine; GABA Antagonists; Kainic Acid; Microelectrodes; Muscimol; Nerve Net; Neurons; Nicotine; Pesticides; Principal Component Analysis; Rats; Rats, Long-Evans; Verapamil | 2014 |
Saturation solubility of nicotine, scopolamine and paracetamol in model stratum corneum lipid matrices.
Topics: Acetaminophen; Epidermis; Lipids; Microscopy; Nicotine; Scattering, Small Angle; Scopolamine; Solubility; X-Ray Diffraction | 2014 |
Effect of Sample Plates and Sample Matrix on the Quantification Capabilities of Surface-Assisted Flowing Atmospheric-Pressure Afterglow Mass Spectrometry (SA-FAPA-MS).
Topics: Acetaminophen; Caffeine; Mass Spectrometry; Nicotine; Progesterone | 2023 |