nicotine has been researched along with a 84543 in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abreo, MA; Anderson, DJ; Arneric, SP; Donnelly-roberts, DL; Garvey, DS; Gunn, DE; Hettinger, AM; Holladay, MW; Lin, NH; Martin, YC; Pavlik, PA; Sullivan, JP; Wasicak, JT; Williams, M | 1 |
| Anderson, DJ; Arneric, SP; Brioni, JD; Buccafusco, JJ; Buckley, MJ; Decker, MW; Donnelly-Roberts, DL; Garvey, DS; Gunn, DE; Holladay, MW; Lin, NH; Marsh, KG; Prendergast, MA; Rodrigues, AD; Ryther, KB; Sullivan, JP; Williams, M | 1 |
| Dart, MJ; Holladay, MW; Lynch, JK | 1 |
| Anderson, DJ; Arneric, SP; Bai, H; Campbell, JE; Donnelly-Roberts, DL; Gunn, DE; He, Y; Holladay, MW; Kuntzweiler, T; Li, Y; Lin, NH; Ryther, KB; Sullivan, JP | 1 |
| Baydyuk, M; Kellar, KJ; Kozikowski, AP; Musachio, JL; Petukhov, PA; Wei, ZL; Xiao, Y; Yuan, H | 1 |
| Bavo, F; Bolchi, C; Fasoli, F; Fumagalli, L; Gotti, C; Moretti, M; Pallavicini, M | 1 |
1 review(s) available for nicotine and a 84543
| Article | Year |
|---|---|
Neuronal nicotinic acetylcholine receptors as targets for drug discovery.
Topics: Acetylcholine; Animals; Binding Sites; Dopamine; Drug Design; Humans; Molecular Structure; Nervous System; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Structure-Activity Relationship | 1997 |
5 other study(ies) available for nicotine and a 84543
| Article | Year |
|---|---|
Novel 3-Pyridyl ethers with subnanomolar affinity for central neuronal nicotinic acetylcholine receptors.
Topics: Alkaloids; Animals; Azocines; Binding, Competitive; Brain; Cell Line; Cell Membrane; Ethers; Ganglia; Humans; Molecular Structure; Neurons; Nicotinic Agonists; Pyridines; Quinolizines; Radioligand Assay; Rats; Receptors, Nicotinic; Structure-Activity Relationship; Tritium | 1996 |
Structure-activity studies on 2-methyl-3-(2(S)-pyrrolidinylmethoxy) pyridine (ABT-089): an orally bioavailable 3-pyridyl ether nicotinic acetylcholine receptor ligand with cognition-enhancing properties.
Topics: Administration, Oral; Alkaloids; Animals; Anti-Anxiety Agents; Azocines; Biological Availability; Bungarotoxins; Cell Line; Cognition; Dogs; Haplorhini; Humans; Hypothermia; Isoxazoles; Ligands; Maze Learning; Mice; Molecular Structure; Psychomotor Performance; Pyrrolidines; Quinolizines; Receptors, Nicotinic; Rubidium; Structure-Activity Relationship | 1997 |
Synthesis and structure-activity relationships of pyridine-modified analogs of 3-[2-((S)-pyrrolidinyl)methoxy]pyridine, A-84543, a potent nicotinic acetylcholine receptor agonist.
Topics: Cell Line; Humans; Ion Transport; Nicotinic Agonists; Pyridines; Pyrrolidines; Rubidium; Structure-Activity Relationship | 1998 |
Novel pyridyl ring C5 substituted analogues of epibatidine and 3-(1-methyl-2(S)-pyrrolidinylmethoxy)pyridine (A-84543) as highly selective agents for neuronal nicotinic acetylcholine receptors containing beta2 subunits.
Topics: Animals; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Ligands; Models, Molecular; Neurons; Protein Subunits; Pyridines; Pyrrolidines; Rats; Receptors, Nicotinic | 2005 |
Novel 5-substituted 3-hydroxyphenyl and 3-nitrophenyl ethers of S-prolinol as α4β2-nicotinic acetylcholine receptor ligands.
Topics: Animals; Humans; Ligands; Nicotinic Agonists; Phenyl Ethers; Pyridines; Pyrrolidines; Rats; Receptors, Nicotinic; Structure-Activity Relationship | 2016 |