Page last updated: 2024-08-26

nicotine and 7-hydroxycoumarin

nicotine has been researched along with 7-hydroxycoumarin in 7 studies

Research

Studies (7)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (57.14)	29.6817
2010's	3 (42.86)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Aygün Kocabaş, N; Cholerton, S; Cok, I; Karakaya, AE; Sardaş, S	1
Hoffmann, E; Jones, J; Rao, YS; Sellers, EM; Tyndale, RF; Xu, B; Xu, C	1
Fujieda, M; Kamataki, T; Kiyotani, K; Peamkrasatam, S; Sriwatanakul, K; Yamazaki, H; Yoovathaworn, K	1
Ashton, M; Asimus, S; Hai, TN; Van Huong, N	1
Biala, G; Budzynska, B; Kruk-Slomka, M; Skalicka-Wozniak, K; Wydrzynska-Kuzma, M	1
Chaudhry, A; Claw, KG; Prasad, B; Schuetz, EG; Stapleton, P; Tanner, JA; Thummel, KE; Tyndale, RF	1
Hirasawa, N; Hiratsuka, M; Hosono, H; Kumondai, M; Maekawa, M; Mano, N; Oda, A; Yamaguchi, H	1

Trials

2 trial(s) available for nicotine and 7-hydroxycoumarin

Article	Year
In vivo evaluation of coumarin and nicotine as probe drugs to predict the metabolic capacity of CYP2A6 due to genetic polymorphism in Thais. Drug metabolism and pharmacokinetics, 2006, Volume: 21, Issue:6 Topics: Administration, Oral; Adolescent; Adult; Anticoagulants; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cotinine; Coumarins; Cytochrome P-450 CYP2A6; Drug Combinations; Female; Gene Frequency; Genotype; Humans; Hydroxyethylrutoside; Male; Middle Aged; Mixed Function Oxygenases; Nicotine; Nicotinic Agonists; Phenotype; Polymethacrylic Acids; Polymorphism, Genetic; Polyvinyls; Thailand; Tobacco Use Cessation Devices; Umbelliferones	2006
Artemisinin and CYP2A6 activity in healthy subjects. European journal of clinical pharmacology, 2008, Volume: 64, Issue:3 Topics: Adult; Antimalarials; Area Under Curve; Artemisinins; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Chromatography, Liquid; Coumarins; Cross-Over Studies; Cytochrome P-450 CYP2A6; Enzyme Induction; Humans; Male; Mixed Function Oxygenases; Nicotine; Tandem Mass Spectrometry; Umbelliferones; Vietnam	2008

Article

Year

In vivo evaluation of coumarin and nicotine as probe drugs to predict the metabolic capacity of CYP2A6 due to genetic polymorphism in Thais.

Drug metabolism and pharmacokinetics, 2006, Volume: 21, Issue:6

Topics: Administration, Oral; Adolescent; Adult; Anticoagulants; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cotinine; Coumarins; Cytochrome P-450 CYP2A6; Drug Combinations; Female; Gene Frequency; Genotype; Humans; Hydroxyethylrutoside; Male; Middle Aged; Mixed Function Oxygenases; Nicotine; Nicotinic Agonists; Phenotype; Polymethacrylic Acids; Polymorphism, Genetic; Polyvinyls; Thailand; Tobacco Use Cessation Devices; Umbelliferones

2006

Artemisinin and CYP2A6 activity in healthy subjects.

European journal of clinical pharmacology, 2008, Volume: 64, Issue:3

Topics: Adult; Antimalarials; Area Under Curve; Artemisinins; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Chromatography, Liquid; Coumarins; Cross-Over Studies; Cytochrome P-450 CYP2A6; Enzyme Induction; Humans; Male; Mixed Function Oxygenases; Nicotine; Tandem Mass Spectrometry; Umbelliferones; Vietnam

2008

Other Studies

5 other study(ies) available for nicotine and 7-hydroxycoumarin

Article	Year
Determination of coumarin metabolism in Turkish population. Human & experimental toxicology, 2001, Volume: 20, Issue:4 Topics: Adult; Aged; Amino Acid Substitution; Aryl Hydrocarbon Hydroxylases; Cotinine; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Female; Gene Frequency; Genotype; Humans; Isoenzymes; Male; Middle Aged; Mixed Function Oxygenases; Nicotine; Phenotype; Point Mutation; Polymorphism, Genetic; Smoking; Turkey; Umbelliferones	2001
An in vivo pilot study characterizing the new CYP2A67, 8, and 10 alleles. Biochemical and biophysical research communications, 2002, Jan-11, Volume: 290, Issue:1* Topics: Alleles; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Asian People; China; Cotinine; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Genetic Variation; Genotype; Humans; Japan; Kinetics; Mixed Function Oxygenases; Models, Molecular; Nicotine; Polymerase Chain Reaction; Polymorphism, Genetic; Sequence Analysis, DNA; Time Factors; Umbelliferones; White People	2002
In vivo modulation of the behavioral effects of nicotine by the coumarins xanthotoxin, bergapten, and umbelliferone. Psychopharmacology, 2016, Volume: 233, Issue:12 Topics: 5-Methoxypsoralen; Animals; Antidepressive Agents; Avoidance Learning; Behavior, Animal; Coumarins; Cytochrome P-450 CYP2A6; Depression; Locomotion; Male; Memory; Methoxsalen; Mice; Nicotine; Nicotinic Agonists; Nootropic Agents; Swimming; Umbelliferones	2016
Predictors of Variation in CYP2A6 mRNA, Protein, and Enzyme Activity in a Human Liver Bank: Influence of Genetic and Nongenetic Factors. The Journal of pharmacology and experimental therapeutics, 2017, Volume: 360, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cytochrome P-450 CYP2A6; Female; Gene Expression Regulation, Enzymologic; Genetic Variation; Genotype; Humans; Infant; Infant, Newborn; Liver; Male; Middle Aged; NADPH-Ferrihemoprotein Reductase; Nicotine; Oxidoreductases; RNA, Messenger; Tissue Banks; Umbelliferones; Young Adult	2017
Functional Characterization of 34 CYP2A6 Allelic Variants by Assessment of Nicotine C-Oxidation and Coumarin 7-Hydroxylation Activities. Drug metabolism and disposition: the biological fate of chemicals, 2017, Volume: 45, Issue:3 Topics: Alleles; Cotinine; Coumarins; Cytochrome P-450 CYP2A6; HEK293 Cells; Humans; Hydroxylation; Kinetics; Microsomes; Models, Molecular; Nicotine; Oxidation-Reduction; Polymorphism, Genetic; Substrate Specificity; Transfection; Umbelliferones	2017