nicotine has been researched along with 6-hydroxynicotine in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 6 (46.15) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Abraham, P; Brieaddy, LE; Carroll, FI; Damaj, MI; Liang, F; Martin, BR; Navarro, HA | 1 |
| HOCHSTEIN, LI; RITTENBERG, SC | 1 |
| BRUEHMUELLER, M; DECKER, K; EBERWEIN, H; GRIES, FA | 1 |
| Aubel, D; El-Baba, MD; Fussenegger, M; Malphettes, L; Schoenmakers, RG; Weber, CC; Weber, W | 1 |
| Fussenegger, M; Malphettes, L; Schoenmakers, RG | 1 |
| Brandsch, R; Ganas, P | 1 |
| Bartunik, HD; Bourenkov, GP; Burghammer, M; Decker, K; Kachalova, GS; Maun, HR; Mengesdorf, T; Riekel, C; Schenk, S | 1 |
| Brandsch, R; Hritcu, L; Mihasan, M; Stefan, M | 2 |
| Liu, W; Ma, Y; Qiu, J; Wei, Y; Wen, R; Wen, Y | 1 |
| Chen, Y; Duan, Y; Gong, X; Ma, G; Yang, J; Zhang, KQ; Zhu, D | 1 |
| Babii, C; Hritcu, L; Ionita, R; Mihasan, M; Motei, DE; Stefan, M | 1 |
| Yildiz, BS; Yildiz, I | 1 |
13 other study(ies) available for nicotine and 6-hydroxynicotine
| Article | Year |
|---|---|
Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2'-substituted 5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes. Epibatidine analogues.
Topics: Analgesics, Non-Narcotic; Animals; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Pain Measurement; Pyridines; Radioligand Assay; Rats; Reaction Time; Receptors, Nicotinic; Structure-Activity Relationship | 2001 |
The bacterial oxidation of nicotine. II. The isolation of the first oxidative product and its identification as (1)-6-hydroxynicotine.
Topics: Bacteria; Nicotine; Oxidation-Reduction | 1959 |
[On the decomposition of nicotine by bacterial enzymes. IV. L-6-Hydroxynicotine as the first intermediate product].
Topics: Arthrobacter; Biochemical Phenomena; Nicotine | 1961 |
A novel mammalian expression system derived from components coordinating nicotine degradation in arthrobacter nicotinovorans pAO1.
Topics: Animals; Arthrobacter; Cell Line; Chick Embryo; Cricetinae; Female; Gene Expression Regulation; Genetic Engineering; Genetic Vectors; HIV-1; Humans; Mice; Neovascularization, Physiologic; Nicotine; Operator Regions, Genetic; Plasmids; Promoter Regions, Genetic; Repressor Proteins; Trans-Activators; Transduction, Genetic; Transgenes; Vascular Endothelial Growth Factor A | 2005 |
6-hydroxy-nicotine-inducible multilevel transgene control in mammalian cells.
Topics: Animals; Biotechnology; CHO Cells; Cloning, Molecular; Cricetinae; Cricetulus; DNA-Binding Proteins; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Genetic Engineering; Genetic Vectors; Humans; Kruppel-Like Transcription Factors; Nicotine; Oxidoreductases; Promoter Regions, Genetic; Repressor Proteins; Silencer Elements, Transcriptional; Transgenes | 2006 |
Uptake of L-nicotine and of 6-hydroxy-L-nicotine by Arthrobacter nicotinovorans and by Escherichia coli is mediated by facilitated diffusion and not by passive diffusion or active transport.
Topics: Arthrobacter; Biological Transport, Active; Cell Membrane; Escherichia coli; Facilitated Diffusion; Membrane Transport Proteins; Nicotine; Oxidoreductases Acting on CH-NH Group Donors; Plasmids; Substrate Specificity | 2009 |
Crystal structure analysis of free and substrate-bound 6-hydroxy-L-nicotine oxidase from Arthrobacter nicotinovorans.
Topics: Arthrobacter; Crystallography, X-Ray; Models, Molecular; Nicotine; Oxidoreductases Acting on CH-NH Group Donors; Phosphatidic Acids; Protein Binding; Protein Structure, Quaternary; Protein Subunits | 2010 |
6-hydroxy-L-nicotine from Arthrobacter nicotinovorans sustain spatial memory formation by decreasing brain oxidative stress in rats.
Topics: Animals; Arthrobacter; Brain; Glutathione Peroxidase; Injections, Intraperitoneal; Lipid Peroxidation; Male; Malondialdehyde; Maze Learning; Memory, Long-Term; Memory, Short-Term; Nicotine; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase | 2013 |
A novel (S)-6-hydroxynicotine oxidase gene from Shinella sp. strain HZN7.
Topics: DNA Transposable Elements; Gene Knockout Techniques; Genetic Complementation Test; Kinetics; Membrane Glycoproteins; Mutagenesis, Insertional; Nicotine; Oxidoreductases; Rhizobiaceae; Substrate Specificity | 2014 |
Enhanced behavioral response by decreasing brain oxidative stress to 6-hydroxy-l-nicotine in Alzheimer's disease rat model.
Topics: Alzheimer Disease; Animals; Hippocampus; Lipid Peroxidation; Male; Maze Learning; Neuroprotective Agents; Nicotine; Oxidative Stress; Rats, Wistar; Spatial Memory | 2015 |
Biodegradation and metabolic pathway of nicotine in Rhodococcus sp. Y22.
Topics: Bacterial Proteins; Biodegradation, Environmental; Gene Expression Regulation, Fungal; Metabolic Networks and Pathways; Metabolomics; Nicotiana; Nicotine; Rhodococcus | 2016 |
Nicotine versus 6-hydroxy-l-nicotine against chlorisondamine induced memory impairment and oxidative stress in the rat hippocampus.
Topics: Animals; Antioxidants; Chlorisondamine; Hippocampus; Male; Maze Learning; Memory Disorders; Nicotine; Nicotinic Antagonists; Oxidative Stress; Rats; Rats, Wistar | 2017 |
Mechanistic study of L-6-hydroxynicotine oxidase by DFT and ONIOM methods.
Topics: Density Functional Theory; Models, Molecular; Molecular Conformation; Nicotine; Oxidoreductases | 2021 |