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nicotine and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

nicotine has been researched along with 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (50.00)29.6817
2010's5 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Akaike, A; Honda, K; Kihara, T; Kume, T; Nakamizo, T; Sawada, H; Shibasaki, H; Shimohama, S1
Ikeuchi, T; Kishi, S; Nakayama, H; Sasaya, H; Shimoke, K; Utsumi, T1
Deng, X; Xin, M1
Arias, E; Gallego-Sandín, S; García, AG; López, MG; Villarroya, M1
Cho, GW; Kim, HY; Kim, SH; Kim, Y; Koh, SH; Noh, MY1
Chauhan, SS; Macha, MA; Matta, A; Ralhan, R; Siu, KW1
Chen, Z; Gao, F; Huang, J; Li, G; Xia, C; Zhang, B; Zheng, X1
Abhold, EL; An, Y; Chen, JS; Kiang, A; Kuo, SZ; Lopez, JP; Ongkeko, WM; Wang-Rodriguez, J; Yu, MA1
Hao, B; Hong, W; Huang, L; Li, B; Liang, C; Liao, B; Peng, F; Peng, G; Peng, H; Pu, J; Ran, P; Ye, X; Yi, E; Zhao, Z; Zheng, M; Zhou, Y1
Guan, Z; Ren, Z; Yang, M; Yu, W1

Other Studies

10 other study(ies) available for nicotine and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

ArticleYear
alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity.
    The Journal of biological chemistry, 2001, Apr-27, Volume: 276, Issue:17

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Androstadienes; Animals; Blotting, Western; Bungarotoxins; Calcineurin; Cell Death; Cells, Cultured; Cerebral Cortex; Chromones; Enzyme Inhibitors; Glutamic Acid; Immunoblotting; Models, Biological; Morpholines; Neurons; Nicotine; Peptide Fragments; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-fyn; Rats; Receptors, Nicotinic; Signal Transduction; Wortmannin

2001
Protective effect of nicotine on tunicamycin-induced apoptosis of PC12h cells.
    Neuroscience letters, 2004, Nov-11, Volume: 370, Issue:2-3

    Topics: Animals; Apoptosis; Benzimidazoles; Cell Survival; Cholinergic Antagonists; Chromones; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Morpholines; Nicotine; Nicotinic Agonists; PC12 Cells; Rats; Tunicamycin

2004
Nicotine inactivation of the proapoptotic function of Bax through phosphorylation.
    The Journal of biological chemistry, 2005, Mar-18, Volume: 280, Issue:11

    Topics: Apoptosis; bcl-2-Associated X Protein; Cell Death; Cell Line, Tumor; Cell Membrane; Cell Survival; Chromones; Cytoplasm; Dose-Response Relationship, Drug; Gene Silencing; Genetic Vectors; Humans; Microscopy, Fluorescence; Models, Biological; Morpholines; Nicotine; Phosphatidylinositol 3-Kinases; Phosphorylation; Plasmids; Protein Binding; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; RNA Interference; RNA, Small Interfering; Serine; Signal Transduction; Subcellular Fractions; Time Factors; Transfection

2005
Unequal neuroprotection afforded by the acetylcholinesterase inhibitors galantamine, donepezil, and rivastigmine in SH-SY5Y neuroblastoma cells: role of nicotinic receptors.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 315, Issue:3

    Topics: Aconitine; Amyloid beta-Peptides; Apoptosis; Benzopyrans; Cell Culture Techniques; Cell Line, Tumor; Cholinesterase Inhibitors; Chromones; Donepezil; Dose-Response Relationship, Drug; Enzyme Inhibitors; Galantamine; Humans; Indans; L-Lactate Dehydrogenase; Morpholines; Neuroblastoma; Neuroprotective Agents; Nicotine; Nitriles; Okadaic Acid; Phenylcarbamates; Phosphatidylinositol 3-Kinases; Piperidines; Proto-Oncogene Proteins c-bcl-2; Receptors, Nicotinic; Rivastigmine

2005
Neuroprotective effects of donepezil through inhibition of GSK-3 activity in amyloid-beta-induced neuronal cell death.
    Journal of neurochemistry, 2009, Volume: 108, Issue:5

    Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Apoptosis; Cell Survival; Cells, Cultured; Cerebral Cortex; Cholinesterase Inhibitors; Chromones; Donepezil; Dose-Response Relationship, Drug; Embryo, Mammalian; Glycogen Synthase Kinase 3; Indans; Indoles; Mecamylamine; Morpholines; Neurons; Neuroprotective Agents; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Peptide Fragments; Phosphorylation; Piperidines; Rats; Rats, Sprague-Dawley; Serine; Sincalide

2009
Guggulsterone targets smokeless tobacco induced PI3K/Akt pathway in head and neck cancer cells.
    PloS one, 2011, Feb-24, Volume: 6, Issue:2

    Topics: bcl-2-Associated X Protein; bcl-Associated Death Protein; Carcinoma, Squamous Cell; Chromones; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Inhibitors; Head and Neck Neoplasms; Humans; Models, Biological; Morpholines; Nicotine; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Pregnenediones; Signal Transduction; Tobacco, Smokeless; Tumor Cells, Cultured; Up-Regulation

2011
Requirement of the phosphatidylinositol 3-kinase/Akt signaling pathway for the effect of nicotine on interleukin-1beta-induced chondrocyte apoptosis in a rat model of osteoarthritis.
    Biochemical and biophysical research communications, 2012, Jul-06, Volume: 423, Issue:3

    Topics: Animals; Apoptosis; Cells, Cultured; Chondrocytes; Chromones; Enzyme Inhibitors; Interleukin-1beta; Male; Morpholines; Nicotine; Osteoarthritis; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases, 70-kDa

2012
Cigarette smoke promotes drug resistance and expansion of cancer stem cell-like side population.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromones; Doxorubicin; Drug Resistance, Neoplasm; Humans; Mitoxantrone; Morpholines; Neoplasm Proteins; Neoplastic Stem Cells; Nicotiana; Nicotine; Nicotinic Agonists; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Transport; Proto-Oncogene Proteins c-akt; Side-Population Cells; Signal Transduction; Smoke

2012
Nicotine-Induced Airway Smooth Muscle Cell Proliferation Involves TRPC6-Dependent Calcium Influx Via α7 nAChR.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2017, Volume: 43, Issue:3

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Calcium; Cell Proliferation; Cell Survival; Cells, Cultured; Chromones; Diglycerides; Humans; Morpholines; Myocytes, Smooth Muscle; Nicotine; Optical Imaging; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; RNA Interference; RNA, Small Interfering; Signal Transduction; TRPC6 Cation Channel; Up-Regulation

2017
Astrocytic α7 Nicotinic Receptor Activation Inhibits Amyloid-β Aggregation by Upregulating Endogenous αB-crystallin through the PI3K/Akt Signaling Pathway.
    Current Alzheimer research, 2019, Volume: 16, Issue:1

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Animals; Astrocytes; Cells, Cultured; Cerebral Cortex; Chromones; Crystallins; Humans; Male; Mice, Inbred C57BL; Mice, Transgenic; Morpholines; Neuroprotective Agents; Nicotine; Nicotinic Agonists; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Primary Cell Culture; Protein Aggregation, Pathological; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Signal Transduction; Up-Regulation

2019