nicotine has been researched along with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (20.00) | 18.7374 |
| 1990's | 12 (30.00) | 18.2507 |
| 2000's | 16 (40.00) | 29.6817 |
| 2010's | 4 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fei, YJ; Ganapathy, V; Kekuda, R; Leibach, FH; Prasad, PD; Wang, H; Wu, X | 1 |
| Chen, J; Conway, SJ; Ganapathy, V; Huang, W; Leibach, FH; Prasad, PD; Rajan, DP; Seth, P; Wu, X | 1 |
| Bard, B; Carrupt, PA; Martel, S | 1 |
| Babu, E; Ganapathy, V; Ho, HT; Itagaki, S; Wang, J; Zhou, M | 1 |
| Behmand, RA; Harik, SI | 1 |
| Lajtha, A; Sershen, H; Wiener, HL | 1 |
| Daniels, AJ; Diliberto, EJ; Reinhard, JF; Viveros, OH | 1 |
| Debler, EA; Hashim, A; Lajtha, A; Sershen, H | 1 |
| Agnati, LF; Fuxe, K; Goldstein, M; Janson, AM; Sundström, E | 1 |
| Hashim, A; Lajtha, A; Sershen, H; Wiener, HL | 1 |
| Perry, TL; Yong, VW | 1 |
| Hashim, A; Lajtha, A; Mason, MF; Reith, ME; Sershen, H | 1 |
| Hashim, A; Lajtha, A; Sershen, H | 1 |
| Clarke, PB; Reuben, M | 1 |
| Eriksson, P | 1 |
| Cavalletti, M; Corsini, GU; Fascetti, F; Fornai, F; Tedeschi, D; Vaglini, F | 1 |
| Castagnoli, KP; Castagnoli, N | 1 |
| Corsini, GU; Fornai, F; Maggio, R; Racagni, G; Riva, M; Vaglini, F | 1 |
| Cui, WY; Gao, ZG; Liu, CG; Zhang, HT | 1 |
| Earl, CD; Ferger, B; Kuschinsky, K; Oertel, WH; Spratt, C; Teismann, P | 1 |
| Lloyd, GK; Menzaghi, F; Schneider, JS; Tinker, JP; Van Velson, M | 1 |
| Domino, EF; Ni, L; Zhang, H | 1 |
| Chancy, CD; Ganapathy, V; Huang, W; Kekuda, R; Rajan, PD; Smith, SB | 1 |
| Jeyarasasingam, G; Quik, M | 1 |
| Bottlaender, M; Coulon, C; Dannals, RF; Dolle, F; Kassiou, M; Loc'h, C; Maziere, B; Musachio, JL; Ottaviani, M | 1 |
| Collins, AC; Grady, SR; Marks, MJ; McCallum, SE; McIntosh, JM; Musachio, J; Quik, M; Sum, JD; Whiteaker, P | 1 |
| Dumery, B; Hapdey, C; Hirsch, EC; Marchand, V; Parain, K; Rousselet, E | 1 |
| Bordia, T; Clementi, F; Fan, H; Gotti, C; Kulak, JM; McIntosh, JM; Quik, M; Vailati, S | 1 |
| Bubl, B; Feuerstein, TJ; Hubbe, U; Huethe, F; Jackisch, R; Löffler, M; McIntosh, JM | 1 |
| Bao, S; Bordia, T; Di Monte, DA; Kim, A; Langston, JW; McCallum, SE; McCormack, A; Parameswaran, N; Quik, M; Tyndale, RF | 1 |
| Decamp, E; Schneider, JS | 1 |
| Chang, YC; Hsu, HJ; Lin, CJ; Liou, HH; Shih, CY; Tsai, YF | 1 |
| Cox, H; Di Monte, D; Langston, JW; O'Leary, K; Parameswaran, N; Quik, M | 1 |
| McIntosh, JM; O'Leary, K; Parameswaran, N; Quik, M | 1 |
| Nath, C; Patel, DK; Patel, S; Singh, C; Singh, K; Singh, MP; Singh, S | 1 |
| Bordia, T; Huang, LZ; Michael McIntosh, J; Parameswaran, N; Quik, M | 1 |
| Nath, C; Patel, DK; Singh, C; Singh, K; Singh, MP; Singh, RK; Singh, S; Singh, VK | 1 |
| Parmar, D; Sharma, A; Singh, K; Singh, MP; Singh, S; Singhal, NK | 1 |
| Bender, CA; Francisco, AB; Glorioso, C; Libert, S; Lugay, FJ; Nicholatos, JW; Salazar, JE; Yeh, T | 1 |
| Chen, J; Hu, LF; Li, LX; Liu, CF; Liu, Y; Lv, DJ; Mao, CJ; Qi, D; Wang, F; Wang, YL; Yang, J | 1 |
2 review(s) available for nicotine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
| Article | Year |
|---|---|
Developmental neurotoxicology in the neonate--effects of pesticides and polychlorinated organic substances.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Child Development; DDT; Environmental Exposure; Humans; Infant, Newborn; Milk, Human; Nicotine; Pesticides; Polychlorinated Biphenyls | 1996 |
Metabolic bioactivation reactions potentially related to drug toxicities.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Biotransformation; Humans; MPTP Poisoning; Nicotine; Pyrrolizidine Alkaloids | 1997 |
38 other study(ies) available for nicotine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
| Article | Year |
|---|---|
Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta.
Topics: Amino Acid Sequence; Animals; Cloning, Molecular; DNA-Binding Proteins; HeLa Cells; Humans; Hydrogen-Ion Concentration; Molecular Sequence Data; Octamer Transcription Factor-3; Oocytes; Placenta; Protein Conformation; Rats; Transcription Factors; Xenopus laevis | 1998 |
Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter.
Topics: Acetylcarnitine; Animals; Biological Transport, Active; Carnitine; Carrier Proteins; Humans; In Situ Hybridization; Kidney; Membrane Proteins; Mice; Myocardium; Organ Specificity; Organic Cation Transport Proteins; Placenta; Rats; RNA, Messenger; Solute Carrier Family 22 Member 5; Tetraethylammonium | 1999 |
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography.
Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical | 2009 |
Electrophysiological characterization of the polyspecific organic cation transporter plasma membrane monoamine transporter.
Topics: Animals; Cell Membrane; Electrophysiological Phenomena; Equilibrative Nucleoside Transport Proteins; Female; Humans; Membrane Potentials; Organic Cation Transport Proteins; Xenopus laevis; Xenopus Proteins | 2012 |
Nicotine enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Behavior, Animal; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Male; Mice; Mice, Inbred Strains; Nervous System; Neurotoxins; Nicotine | 1992 |
Dopamine D1 receptor and dopamine D2 receptor binding activity changes during chronic administration of nicotine in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Benzazepines; Corpus Striatum; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Nicotine; Pyridines; Receptors, Dopamine; Spiperone | 1989 |
Subcellular compartmentalization of 1-methyl-4-phenylpyridinium with catecholamines in adrenal medullary chromaffin vesicles may explain the lack of toxicity to adrenal chromaffin cells.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Adrenal Medulla; Animals; Calcium; Catecholamines; Cattle; Cell Compartmentation; Cells, Cultured; Desipramine; Digitonin; Drug Interactions; Nicotine; Pyridines; Pyridinium Compounds; Subcellular Fractions; Tetrabenazine; Tyrosine 3-Monooxygenase | 1987 |
Ascorbic acid and striatal transport of [3H] 1-methyl-4-phenylpyridine (MPP+) and [3H] dopamine.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Ascorbic Acid; Biological Transport; Cocaine; Corpus Striatum; Dopamine; Kinetics; Mazindol; Mice; Nicotine; Piperazines; Pyridines; Synaptosomes | 1988 |
Chronic nicotine treatment partly protects against the 1-methyl-4-phenyl-2,3,6-tetrahydropyridine-induced degeneration of nigrostriatal dopamine neurons in the black mouse.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Mice; Mice, Inbred C57BL; Nerve Degeneration; Nicotine; Pyridines; Receptors, Dopamine; Substantia Nigra | 1988 |
Effect of chronic oral nicotine on dopaminergic function in the MPTP-treated mouse.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Administration, Oral; Animals; Corpus Striatum; Dopamine; Mice; Mice, Inbred BALB C; Monoamine Oxidase; Nicotine; Pyridines | 1988 |
Monoamine oxidase B, smoking, and Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Blood Platelets; Brain; Humans; Hydrazines; Isoenzymes; Mice; Mice, Inbred C57BL; Monoamine Oxidase; Nicotine; Parkinson Disease; Pyridines; Smoking; Thiocyanates | 1986 |
Effect of nicotine and amphetamine on the neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cell Membrane; Corpus Striatum; Dextroamphetamine; Dopamine; Drug Synergism; Female; Mazindol; Mice; Mice, Inbred BALB C; Nicotine; Pyridines | 1986 |
Behavioral and biochemical effects of nicotine in an MPTP-induced mouse model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Drug Tolerance; Female; Homovanillic Acid; Mice; Mice, Inbred BALB C; Motor Activity; Nicotine; Olfactory Bulb; Parkinson Disease; Pyridines | 1987 |
Inhibition by dizocilpine (MK-801) of striatal dopamine release induced by MPTP and MPP+: possible action at the dopamine transporter.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Carrier Proteins; Cell Membrane; Dextroamphetamine; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; In Vitro Techniques; Male; Membrane Glycoproteins; Membrane Transport Proteins; Neostriatum; Nerve Tissue Proteins; Nicotine; Rats; Rats, Sprague-Dawley; Synaptosomes | 1995 |
Striatal MPP+ levels do not necessarily correlate with striatal dopamine levels after MPTP treatment in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Acetaldehyde; Animals; Chromatography, High Pressure Liquid; Clonidine; Corpus Striatum; Ditiocarb; Dizocilpine Maleate; Dopamine; Dopamine Uptake Inhibitors; Kinetics; Male; Metabolic Clearance Rate; Mice; Mice, Inbred C57BL; MPTP Poisoning; Nicotine; Piperazines; Selegiline; Serotonin | 1996 |
Striatal increase of neurotrophic factors as a mechanism of nicotine protection in experimental parkinsonism.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain-Derived Neurotrophic Factor; Cells, Cultured; Dopamine Uptake Inhibitors; Fibroblast Growth Factor 2; Male; Mesencephalon; Methamphetamine; Mice; Mice, Inbred C57BL; Neostriatum; Neuroprotective Agents; Neurotoxins; Nicotine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tyrosine 3-Monooxygenase | 1997 |
Effects of nicotine on 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine-induced depression of striatal dopamine content and spontaneous locomotor activity in C57 black mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Dopamine; Dopamine Agents; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neostriatum; Nicotine; Nicotinic Agonists; Parkinson Disease | 1998 |
Effects of nicotine on hydroxyl free radical formation in vitro and on MPTP-induced neurotoxicity in vivo.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Body Weight; Cardiotonic Agents; Cyclic N-Oxides; Dopamine; Dopamine Agents; Drug Interactions; Free Radical Scavengers; Hydroxyl Radical; Locomotion; Male; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Nitrogen Oxides; Parkinson Disease, Secondary | 1998 |
Nicotinic acetylcholine receptor agonist SIB-1508Y improves cognitive functioning in chronic low-dose MPTP-treated monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Attention; Cognition Disorders; Conditioning, Operant; Discrimination Learning; Dopamine Agents; Female; Levodopa; Macaca fascicularis; Macaca nemestrina; Male; Memory, Short-Term; Nicotine; Nicotinic Agonists; Pattern Recognition, Visual; Pyridines; Pyrrolidines; Receptors, Nicotinic; Space Perception | 1999 |
Nicotine alone and in combination with L-DOPA methyl ester or the D(2) agonist N-0923 in MPTP-induced chronic hemiparkinsonian monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Dopamine Agonists; Drug Interactions; Female; Levodopa; Macaca nemestrina; Motor Activity; Nicotine; Parkinson Disease, Secondary; Receptors, Dopamine D2; Rotation; Tetrahydronaphthalenes; Thiophenes | 1999 |
Expression of the extraneuronal monoamine transporter in RPE and neural retina.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Amphetamine; Animals; Biogenic Monoamines; Blotting, Northern; Carrier Proteins; Cells, Cultured; Eye; Female; Gene Expression; Humans; Hydrogen-Ion Concentration; In Situ Hybridization; Kinetics; Methamphetamine; Mice; Mice, Inbred ICR; Nicotine; Organic Cation Transport Proteins; Pigment Epithelium of Eye; Procainamide; Retina; RNA, Messenger; Steroids; Tetraethylammonium; Time Factors | 2000 |
Nicotinic receptors and Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Basal Ganglia; Dopamine Agents; Drug Interactions; Humans; Mesencephalon; Neuroprotective Agents; Nicotine; Parkinson Disease, Secondary; Receptors, Nicotinic; RNA, Messenger; Saimiri; Substantia Nigra; Tissue Distribution | 2000 |
Pharmacological evaluation of a Br-76 analog of epibatidine: a potent ligand for studying brain nicotinic acetylcholine receptors.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Alkaloids; Animals; Autoradiography; Azocines; Brain; Bridged Bicyclo Compounds, Heterocyclic; Dopamine Agents; Ellipticines; In Vitro Techniques; Male; Nicotine; Nicotinic Agonists; Pyridines; Quinolizines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Nicotinic; Time Factors; Tomography, Emission-Computed | 2002 |
Differential declines in striatal nicotinic receptor subtype function after nigrostriatal damage in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Conotoxins; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; MPTP Poisoning; Nerve Tissue Proteins; Neurons; Nicotine; Potassium; Receptors, Dopamine; Receptors, Nicotinic | 2003 |
Cigarette smoke and nicotine protect dopaminergic neurons against the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Parkinsonian toxin.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Dopamine; Male; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Nicotine; Parkinsonian Disorders; Smoking | 2003 |
Subunit composition of nicotinic receptors in monkey striatum: effect of treatments with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine or L-DOPA.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Alkaloids; Amino Acid Sequence; Animals; Antibodies; Autoradiography; Azocines; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cerebral Cortex; Corpus Striatum; Humans; Iodine Radioisotopes; Levodopa; Molecular Sequence Data; Nicotine; Protein Subunits; Pyridines; Quinolizines; Receptors, Nicotinic; Saimiri | 2005 |
Dopamine release in human neocortical slices: characterization of inhibitory autoreceptors and of nicotinic acetylcholine receptor-evoked release.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adolescent; Adult; Aged; Alkaloids; Analysis of Variance; Animals; Autoreceptors; Azocines; Calcium; Child; Child, Preschool; Domperidone; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Feedback; Female; Fluvoxamine; Humans; In Vitro Techniques; Isoxazoles; Male; Maprotiline; Mice; Middle Aged; Neocortex; Nicotine; Nicotinic Antagonists; Potassium; Pyrrolidines; Quinolizines; Rats; Receptors, Nicotinic; Sulpiride; Time Factors; Tritium | 2006 |
Chronic oral nicotine treatment protects against striatal degeneration in MPTP-treated primates.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Administration, Oral; Animals; Biomarkers; Cerebral Cortex; Corpus Striatum; Dopamine; Drug Administration Schedule; Female; Monoamine Oxidase; Nerve Degeneration; Neurons; Neurotoxins; Nicotine; Nicotinic Agonists; Receptors, Nicotinic; Saimiri; Substantia Nigra; Tyrosine 3-Monooxygenase | 2006 |
Effects of nicotinic therapies on attention and executive functions in chronic low-dose MPTP-treated monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Animals; Attention; Behavior, Animal; Disease Models, Animal; Macaca mulatta; Male; MPTP Poisoning; Neuropsychological Tests; Nicotine; Nicotinic Agonists; Phenols; Problem Solving; Pyrrolidines; Reaction Time | 2006 |
Interaction between nicotine and MPTP/MPP+ in rat brain endothelial cells.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Algorithms; Animals; Blood-Brain Barrier; Brain; Cells, Cultured; Cotinine; Data Interpretation, Statistical; Dopamine Agents; Dopamine Antagonists; Endothelial Cells; Extracellular Space; Male; Microdialysis; MPTP Poisoning; Nicotine; Nicotinic Agonists; Nonlinear Dynamics; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction | 2007 |
Nicotine reduces levodopa-induced dyskinesias in lesioned monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Circadian Rhythm; Dyskinesia, Drug-Induced; Levodopa; Nicotine; Nicotinic Agonists; Parkinsonian Disorders; Saimiri; Substantia Nigra; Time Factors | 2007 |
Cotinine selectively activates a subpopulation of alpha3/alpha6beta2 nicotinic receptors in monkey striatum.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Azetidines; Brain; Cocaine; Conotoxins; Cotinine; Dopamine; Dopamine Agents; Female; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Saimiri | 2008 |
Nicotine and caffeine-mediated modulation in the expression of toxicant responsive genes and vesicular monoamine transporter-2 in 1-methyl 4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease phenotype in mouse.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Animals; Caffeine; Central Nervous System Stimulants; Corpus Striatum; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2E1; Disease Models, Animal; Drug Interactions; Gene Expression Regulation; Glutathione Transferase; Male; Mice; MPTP Poisoning; Nicotine; Nicotinic Agonists; Organic Anion Transporters; Time Factors; Vesicular Monoamine Transport Proteins | 2008 |
Nicotine is neuroprotective when administered before but not after nigrostriatal damage in rats and monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amphetamine; Analysis of Variance; Animals; Autoradiography; Cocaine; Conotoxins; Corpus Striatum; Cotinine; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Iodine Isotopes; Male; Motor Activity; Neuroprotective Agents; Neurotoxicity Syndromes; Nicotine; Oxidopamine; Protein Binding; Rats; Rats, Sprague-Dawley; Saimiri; Substantia Nigra; Time Factors | 2009 |
The expression of CYP2D22, an ortholog of human CYP2D6, in mouse striatum and its modulation in 1-methyl 4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease phenotype and nicotine-mediated neuroprotection.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Gene Expression Regulation; Humans; Male; Mice; Neuroprotective Agents; Neurotoxins; Nicotine; Parkinson Disease; Phenotype; Time Factors | 2009 |
Nicotine- and caffeine-mediated changes in gene expression patterns of MPTP-lesioned mouse striatum: Implications in neuroprotection mechanism.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apoptosis; Base Sequence; Caffeine; Disease Models, Animal; Gene Expression Regulation; Injections, Intraperitoneal; Male; Mice; MPTP Poisoning; Neostriatum; Neuroprotective Agents; Neurotoxins; Nicotine; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Parkinson Disease; Receptors, Interleukin-1; Reverse Transcriptase Polymerase Chain Reaction; Time Factors | 2010 |
Nicotine promotes neuron survival and partially protects from Parkinson's disease by suppressing SIRT6.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aged; Aged, 80 and over; Animals; Animals, Newborn; Apoptosis; Brain; Cell Death; Disease Models, Animal; Exploratory Behavior; Female; Gene Expression Regulation; Humans; Male; Mice; Mice, Transgenic; Neurons; Nicotine; Nicotinic Agonists; Parkinson Disease; Sirtuins | 2018 |
Nicotine improved the olfactory impairment in MPTP-induced mouse model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Behavior, Animal; Choline O-Acetyltransferase; Cholinergic Neurons; Disease Models, Animal; Dopaminergic Neurons; Locomotion; Male; Mice, Inbred C57BL; MPTP Poisoning; Nicotine; Nicotinic Agonists; Olfactory Bulb; Olfactory Perception; Signal Transduction; Smell; Tyrosine 3-Monooxygenase | 2019 |