nicotine 1-n-oxide has been researched along with cotinine in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (43.75) | 18.7374 |
| 1990's | 4 (25.00) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujihara, S; Kurogochi, Y; Nakashima, T; Nakayama, H | 1 |
| Crooks, PA; Nwosu, CG | 1 |
| Hoffmann, D; LaVoie, EJ; Mu, B; Rivenson, A; Shigematsu, A | 1 |
| Axelrad, CM; Haley, NJ; LaVoie, EJ; Sepkovic, DW | 1 |
| Lekić, M; Nikolin, B; Rashid Mahmud, MA; Vísnjevac, O | 1 |
| Damiano, MD; Dvorchik, BH; Kyerematen, GA; Vesell, ES | 1 |
| Kainzbauer, J; Richter, O; Stehlik, G; Tausch, H | 1 |
| Caldwell, WS; de Bethizy, JD; Doolittle, DJ; Hayes, AW; Lee, CK; Winegar, R | 1 |
| Andersson, G; Axéll, T; Curvall, M | 1 |
| Berkman, CE; Cashman, JR; Park, SB; Wrighton, SA | 1 |
| Andersson, G; Curvall, M; Vala, EK | 1 |
| Itoh, K; Nomura, A; Ochiai, Y; Sakurai, E; Tanaka, Y | 1 |
| Florek, E; Kulza, M; Loba, U; Piekoszewski, W; Wilimowska, J | 1 |
| Andrenyak, DM; Fleckenstein, AE; Nielsen, SM; Vieira-Brock, PL; Wilkins, DG | 1 |
| Craig, EL; Cui, JZ; Miksys, S; Novalen, M; Tyndale, RF; Zhao, B | 1 |
| Abu-Awwad, A; Arafat, T; Schmitz, OJ | 1 |
16 other study(ies) available for nicotine 1-n-oxide and cotinine
| Article | Year |
|---|---|
Formation of two major nicotine metabolites in livers of guinea pigs.
Topics: Amines; Animals; Cotinine; Cyclic N-Oxides; Electron Transport; Flavin-Adenine Dinucleotide; Guinea Pigs; Immunologic Techniques; Liver; Methimazole; Metyrapone; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Nicotine; Oxidation-Reduction | 1987 |
Species variation and stereoselectivity in the metabolism of nicotine enantiomers.
Topics: Animals; Cotinine; Cricetinae; Cyclic N-Oxides; Female; Guinea Pigs; Male; Mesocricetus; Nicotine; Rabbits; Rats; Rats, Inbred Strains; Sex Factors; Species Specificity; Stereoisomerism | 1988 |
Evaluation of the effects of cotinine and nicotine-N'-oxides on the development of tumors in rats initiated with N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide.
Topics: Animals; Body Weight; Carcinogens; Cocarcinogenesis; Cotinine; Cyclic N-Oxides; Digestive System Neoplasms; Drinking; Eating; FANFT; Male; Nicotine; Pyrrolidinones; Rats; Rats, Inbred F344; Smoking; Stereoisomerism; Urinary Bladder Neoplasms | 1985 |
Thyroid hormone concentrations in rats after chronic nicotine metabolite administration.
Topics: Animals; Body Weight; Cotinine; Cyclic N-Oxides; Male; Nicotine; Pyrrolidinones; Rats; Rats, Inbred F344; Thyroid Hormones; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1984 |
Investigation of the content and ratio of cotinine and nicotine-1'-N-oxide in the urine of smokers.
Topics: Adult; Aged; Cotinine; Cyclic N-Oxides; Female; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Nicotine; Pyrrolidinones; Smoking | 1983 |
Smoking-induced changes in nicotine disposition: application of a new HPLC assay for nicotine and its metabolites.
Topics: Adult; Chromatography, High Pressure Liquid; Cotinine; Cyclic N-Oxides; Half-Life; Humans; Kinetics; Male; Nicotine; Smoking | 1982 |
Improved method for routine determination of nicotine and its main metabolites in biological fluids.
Topics: Chromatography, Gas; Cotinine; Cyclic N-Oxides; Humans; Nicotine | 1982 |
The genotoxic potential of nicotine and its major metabolites.
Topics: Animals; CHO Cells; Cotinine; Cricetinae; Cyclic N-Oxides; Fluorenes; Mutagenicity Tests; Mutagens; Mutation; Nicotine; Salmonella typhimurium; Sister Chromatid Exchange | 1995 |
Reduction in nicotine intake and oral mucosal changes among users of Swedish oral moist snuff after switching to a low-nicotine product.
Topics: Adult; Cotinine; Cyclic N-Oxides; Glucuronates; Humans; Mouth Diseases; Mouth Mucosa; Nicotine; Plants, Toxic; Saliva; Sweden; Time Factors; Tobacco, Smokeless | 1995 |
In vitro-in vivo correlations of human (S)-nicotine metabolism.
Topics: Adult; Aldehyde Oxidase; Aldehyde Oxidoreductases; Barbiturates; Biotransformation; Cotinine; Cyclic N-Oxides; Female; Humans; Kinetics; Male; Microsomes, Liver; Middle Aged; Nicotine; Stereoisomerism | 1995 |
The influence of cigarette consumption and smoking machine yields of tar and nicotine on the nicotine uptake and oral mucosal lesions in smokers.
Topics: Adult; Cotinine; Cyclic N-Oxides; Environmental Exposure; Glucuronates; Humans; Leukoedema, Oral; Leukoplakia, Oral; Male; Middle Aged; Mouth Diseases; Mouth Mucosa; Nicotiana; Nicotine; Plants, Toxic; Prevalence; Smoking; Tars; Time Factors; Tongue, Hairy | 1997 |
Metabolism of nicotine in rat lung microvascular endothelial cells.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cells, Cultured; Chromatography, High Pressure Liquid; Cotinine; Cyclic N-Oxides; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; Lung; Male; Membrane Proteins; Microcirculation; Nicotine; Oxygenases; Rats; Rats, Wistar; Steroid 16-alpha-Hydroxylase | 2006 |
[Development of analytical method for determination nicotine metabolites in urine].
Topics: Biomarkers; Chromatography, High Pressure Liquid; Cotinine; Cyclic N-Oxides; Environmental Exposure; Environmental Monitoring; Humans; Nicotine; Predictive Value of Tests | 2009 |
Age-related differences in the disposition of nicotine and metabolites in rat brain and plasma.
Topics: Administration, Cutaneous; Adolescent; Adult; Aging; Animals; Brain; Cotinine; Cyclic N-Oxides; Humans; Male; Nicotine; Rats; Rats, Sprague-Dawley | 2013 |
Nicotine pharmacokinetics in rats is altered as a function of age, impacting the interpretation of animal model data.
Topics: Animals; Area Under Curve; Brain; Cotinine; Cyclic N-Oxides; Male; Models, Animal; Nicotine; Plasma; Rats; Rats, Wistar | 2014 |
Simultaneous determination of nicotine, cotinine, and nicotine N-oxide in human plasma, semen, and sperm by LC-Orbitrap MS.
Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Cotinine; Cyclic N-Oxides; Humans; Limit of Detection; Male; Nicotine; Semen; Spectrometry, Mass, Electrospray Ionization; Spermatozoa; Tobacco Smoking | 2016 |