Compounds > nicotinamide mononucleotide
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nicotinamide mononucleotide and niacinamide

nicotinamide mononucleotide has been researched along with niacinamide in 105 studies

Research

Studies (105)

TimeframeStudies, this research(%)All Research%
pre-199040 (38.10)18.7374
1990's8 (7.62)18.2507
2000's11 (10.48)29.6817
2010's20 (19.05)24.3611
2020's26 (24.76)2.80

Authors

AuthorsStudies
Abell, C; Blundell, TL; Ciulli, A; Smith, AG; Williams, G1
Claycomb, WC1
Brady, RO; Brewer, HB; Fishman, PH; Moss, J; Osborne, JC; Vaughan, M1
Reisbig, RR; Woody, RW1
Gross, CJ; Henderson, LM1
Brunngraber, EF; Chargaff, E1
Elliott, G; Rechsteiner, M1
Jacobson, MK; Lange, RA1
Bull, HG; Cordes, EH; Ferraz, JP1
Foster, JW; Kinney, DM; Moat, AG1
Boland, MP; Davies, LC; Friedlos, F; Jarman, M; Knox, RJ1
Niven, DF; O'Reilly, T3
Durand, P; Langrené, S; Le Goffic, F; Sicsic, S1
Carpenter, KJ; Cook, NE1
Chaykin, S; Kuwahara, M1
Belavady, B; Khan, L; Rao, PU1
Blumenstein, M; Raftery, MA1
Catanzarite, V; Rechsteiner, M1
Dmochowska, G; Frackowiak, B; Kaniuga, Z1
Branzoli, U; Massey, V1
Henderson, LM; Lan, SJ; Lin, LF; Richardson, AH1
Henderson, LM; Lin, LF1
Scholz, G; Streffer, C1
Kasărov, LB; Moat, AG1
Burkhalter, A; MacGregor, JT1
Ise, N; Okubo, T1
Leroi, GE; Patrick, DM; Wilson, JE1
Heik, P; Jeck, R; Woenckhaus, C1
Anderson, BM; Yuan, JH1
Eklund, H; Jones, TA; Samama, JP1
Foster, J; Liu, G; Manlapaz-Ramos, P; Olivera, BM1
Amos, H; Lively, MK; Lombardi, D; Mandel, KG1
Heard, JT; Tritz, GJ1
Behr, A; Gholson, RK; Taguchi, H1
Hankes, LV; Wessels, LM; Yeh, YK1
McPheat, WL1
Baskowsky-Foster, AM; Foster, JW1
Ajioka, J; Elliott, GC; Okada, CY1
Boink, AB; Hegger, C; Jansen, EH; Meulenbelt, J; van den Berg, RH1
Callis, P; Gryczynski, I; Kierdaszuk, B; Lakowicz, JR; Malak, H1
Micheli, V; Sestini, S1
Hagen, T; Ziegler, M1
Lee, HC; Munshi, C; Sauve, AA; Schramm, VL1
Kissner, R; Koppenol, WH; Prütz, WA; Rüegger, H1
Fiske, MJ; Green, BA; Herbert, M; Kemmer, G; Kraiss, A; Reidl, J; Reilly, TJ; Schlör, S; Schmidt-Brauns, J; Smith, A; Zlotnik, GW1
Lauhon, CT; Szostak, JW1
Ariyoshi, M; Hirano, T; Ishihara, K; Jingami, H; Morikawa, K; Yamamoto-Katayama, S1
HOLECEK, V; KULICH, V1
CHAMBON, P; MANDEL, P; WEILL, JD1
HANDLER, P; LEDER, IG1
Ali, TH; Elzainy, TA1
Bergthorsson, U; Grose, JH; Khodaverdian, B; Roth, JR; Sterneckert, J; Xu, Y1
Hara, N; Osago, H; Shibata, T; Tsuchiya, M; Yamada, K2
Gerdes, SY; Kurnasov, OV; Osterman, AL; Overbeek, R; Polanuyer, B; Shatalin, K; Sloutsky, R; Vonstein, V1
Pichersky, E; Wang, G1
Chiarugi, A; Formentini, L; Moroni, F1
Belenky, P; Bogan, KL; Brenner, C; Burant, CF; Evans, C; Kennedy, R; Song, P1
Amici, A; Brunetti, L; Di Stefano, M; Galassi, L; Magni, G; Orsomando, G; Ruggieri, S1
Ashihara, H; Katahira, R; Mimura, T; Sasamoto, H; Watanabe, S; Yin, Y1
Bam, R; Barlogie, B; Epstein, J; Khan, S; Li, X; Ling, W; Usmani, S; van Rhee, F; Venkateshaiah, SU; Yaccoby, S1
Masumoto, M; Niimi, T; Orita, M; Takeuchi, M; Yamamoto, T; Yokota, H1
Kraus, WL1
Bianchi, G; Bruzzone, S; Emionite, L; Magnone, M; Nahimana, A; Nencioni, A; Raffaelli, N; Raffaghello, L; Sociali, G; Sturla, L; Vigliarolo, T; Zamporlini, F1
Avelar-González, FJ; Guerrero-Barrera, AL; Jacques, M; Labrie, J; Loera-Muro, A; Oropeza-Navarro, R; Tremblay, YD1
Kristian, T; Long, A; Owens, K; Park, JH1
Kawamura, T; Mori, N; Shibata, K1
Auwerx, J; Boutant, M; Brenner, C; Canela, N; Cantó, C; Joffraud, M; Kulkarni, SS; Migaud, ME; Ras, R; Ratajczak, J; Redpath, P; Rodrigues, M; Trammell, SA; Yanes, O1
Amici, A; Mazzola, F; Mozzon, M; Orsomando, G; Raffaelli, N; Ruggieri, S; Ummarino, S; Zamporlini, F1
Djouder, N; Garrido, A1
Baur, JA; Imai, SI; Yoshino, J1
Atomi, H; Hachisuka, SI; Sato, T1
Baur, JA; Chellappa, K; Davila, A; Liu, L; Migaud, ME; Nakamaru-Ogiso, E; Paolella, LM; Rabinowitz, JD; Redpath, P; Zhang, Z1
Brenner, C; Cambronne, XA; Cohen, MS; Goodman, RH; Liu, HW; Migaud, ME; Schmidt, MS; Smith, CB1
Klimova, N; Kristian, T1
Badalzadeh, R; Hosseini, L; Mahmoudi, J; Vafaee, MS1
Harlan, BA; Killoy, KM; Pehar, M; Vargas, MR1
Fujita, M; Imai, SI; Inagaki, E; Irie, J; Itoh, H; Mitsuishi, M; Nabeshima, YI; Nakaya, H; Okano, H; Ono, T; Shigaki, S; Tsubota, K; Yamaguchi, S; Yamashita, K; Yasui, M; Yukioka, H1
Braidy, N; Liu, Y1
Deterding, LJ; Fan, W; Kabanov, AV; Lee, E; Li, JL; Li, L; Li, W; Li, X; Lih, FB; Lim, C; Liu, J; Locasale, JW; Makarov, MV; Migaud, ME; Randall, TA; Shats, I; Sokolsky, M; Williams, JG; Wu, X; Xu, X1
Campagna, R; Chlopicki, S; Kuś, K; Kutryb-Zając, B; Mateuszuk, Ł; Smolenski, RT; Słominska, EM1
Choi, JY; Kang, BE; Ryu, D; Stein, S1
Xia, J; Xu, B; Zhao, N1
Ishii, J; Kondo, A; Makino, H; Shoji, S; Yamaji, T1
Khodorkovskiy, M; Kropotov, A; Kulikova, V; Migaud, ME; Nerinovski, K; Nikiforov, A; Solovjeva, L; Sudnitsyna, J; Svetlova, M; Yakimov, A; Ziegler, M1
Dohra, H; Idogaki, H; Iijima, K; Nishikawa, K; Sugiyama, K; Tokimoto, Y; Yoshida, N; Yoshino, M1
Feng, Y; Guo, X; Li, Q; Ning, S; Wang, J; Wang, L; Wang, Q; Wang, X; Zhao, ZK1
Liu, Y; Yasawong, M; Yu, B1
Chai, H; Chen, Y; Cheng, Y; Liu, X; Wei, Z1
Kim, BS; Maharjan, A; Singhvi, M1
Campbell, JM1
Auchus, RJ; Braun, RT; Breynaert, E; Casalino, LP; Chandran, CV; Chauvin, JR; De Man, WL; Delcour, JA; Ding, S; He, L; Huang, X; Huang, Z; Im, SC; Jung, HY; Khodade, VS; Krishnarjuna, B; Li, L; Li, N; Li, Q; Marte, J; Martens, JA; Myslinski, Z; Pratt, DA; Radhakrishnan, S; Ramamoorthy, A; Ravula, T; Rodriguez, D; Song, L; Toscano, JP; Unruh, MA; Wang, X; Wang, Z; Wouters, AGB; Wu, Z; Yu, S; Zhang, T; Zhang, W; Zhou, J1
Li, Q; Meng, D; You, C1
Kong, LH; Liu, TY; Qin, JY; Xu, WN; Yao, QS; Zhang, XH1
Borrelli, M; Kahn, B; Libby, T1
Braidy, N; Helman, T1
Chabloz, S; Ewald, CY; Lapides, RA; Roider, E; Sharma, A1
Cheng, J; Liu, R; Ma, H; Yu, J; Zhao, Y; Zhu, X1
Acharjee, A; Anderson, DG; Astuti, D; Barrett, T; Buganim, Y; Cartwright, D; Chipara, M; Cohen, MA; Frickel, EM; Gsponer, J; Huerta-Uribe, A; Hughes, GW; Jaenisch, R; Kataura, T; Kauffman, KJ; Korolchuk, VI; Korsgen, ME; Kuechler, ER; Lara-Reyna, S; Lavery, GG; Maddocks, ODK; Otten, EG; Palhegyi, AM; Panda, PK; Roberts, J; Rosenstock, TR; Sahay, G; Sarkar, S; Sedlackova, L; Seranova, E; Silva, LFSE; Sun, C; Tennant, DA; Torresi, J; Trushin, S; Trushina, E; Wang, H; Ward, C; Zatyka, M; Zhang, S1
Borén, J; Doganay, HL; Jin, H; Li, X; Mardinoglu, A; Nielsen, J; Ozturk, G; Turkez, H; Uhlén, M; Yang, H; Zhang, C1
Alegre, GFS; Pastore, GM1
Bifulco, E; Ferrario, E; Houry, D; Kursula, P; Niere, M; Raasakka, A; Ziegler, M1
Goswami, L; Kafle, SR; Kim, BS; Kushwaha, A; Maharjan, A1

Reviews

13 review(s) available for nicotinamide mononucleotide and niacinamide

ArticleYear
Significance of V-factor dependency in the taxonomy of Haemophilus species and related organisms.
    International journal of systematic bacteriology, 1990, Volume: 40, Issue:1

    Topics: Actinobacillus; Haemophilus; NAD; Niacinamide; Nicotinamide Mononucleotide; Pasteurella; Pasteurellaceae; Pyridines; Pyridinium Compounds; Structure-Activity Relationship

1990
NAD
    Trends in cancer, 2017, Volume: 3, Issue:8

    Topics: Aging; Humans; Incidence; Life Expectancy; Longevity; NAD; Neoplasms; Niacinamide; Nicotinamide Mononucleotide; Vitamin B Complex

2017
NAD
    Cell metabolism, 2018, 03-06, Volume: 27, Issue:3

    Topics: Aging; Animals; Humans; NAD; Niacinamide; Nicotinamide Mononucleotide; Pyridinium Compounds

2018
Multi-targeted Effect of Nicotinamide Mononucleotide on Brain Bioenergetic Metabolism.
    Neurochemical research, 2019, Volume: 44, Issue:10

    Topics: Animals; Brain; Humans; Hydrolases; Mitochondria; NAD; Neurodegenerative Diseases; Niacinamide; Nicotinamide Mononucleotide

2019
Nicotinamide adenine dinucleotide emerges as a therapeutic target in aging and ischemic conditions.
    Biogerontology, 2019, Volume: 20, Issue:4

    Topics: Aging; Drug Discovery; Humans; Ischemia; Mitochondria; NAD; Niacinamide; Nicotinamide Mononucleotide; Pyridinium Compounds

2019
NAD+ therapy in age-related degenerative disorders: A benefit/risk analysis.
    Experimental gerontology, 2020, Volume: 132

    Topics: Aging; Animals; Humans; Inflammation; Mice; NAD; Neurodegenerative Diseases; Niacinamide; Nicotinamide Mononucleotide; Oxidative Stress; Pyridinium Compounds; Rats; Risk Assessment

2020
Implications of NAD
    European journal of clinical investigation, 2020, Volume: 50, Issue:10

    Topics: ADP-ribosyl Cyclase; Aging; Animals; Biosynthetic Pathways; Carboxy-Lyases; Clinical Trials as Topic; Enzyme Inhibitors; Gastrointestinal Microbiome; Humans; NAD; Niacinamide; Nicotinamide Mononucleotide; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Probiotics; Pyridinium Compounds; Sirtuins; Translational Research, Biomedical

2020
Nicotinamide mononucleotide: An emerging nutraceutical against cardiac aging?
    Current opinion in pharmacology, 2021, Volume: 60

    Topics: Aging; Dietary Supplements; Humans; NAD; Niacinamide; Nicotinamide Mononucleotide

2021
Supplementation with NAD
    Nutrients, 2022, Aug-07, Volume: 14, Issue:15

    Topics: Animals; Cognitive Dysfunction; Dietary Supplements; Humans; NAD; Niacin; Niacinamide; Nicotinamide Mononucleotide

2022
A Narrative Review of Nicotinamide Adenine Dinucleotide (NAD)+ Intermediates Nicotinamide Riboside and Nicotinamide Mononucleotide for Keratinocyte Carcinoma Risk Reduction.
    Journal of drugs in dermatology : JDD, 2022, Oct-01, Volume: 21, Issue:10

    Topics: Carcinoma; Humans; Keratinocytes; NAD; Niacinamide; Nicotinamide Mononucleotide; Pyridinium Compounds; Risk Reduction Behavior

2022
Importance of NAD+ Anabolism in Metabolic, Cardiovascular and Neurodegenerative Disorders.
    Drugs & aging, 2023, Volume: 40, Issue:1

    Topics: Aging; Dietary Supplements; Humans; NAD; Neurodegenerative Diseases; Niacinamide; Nicotinamide Mononucleotide

2023
Potential Synergistic Supplementation of NAD+ Promoting Compounds as a Strategy for Increasing Healthspan.
    Nutrients, 2023, Jan-14, Volume: 15, Issue:2

    Topics: Adolescent; Dietary Supplements; Humans; NAD; Niacinamide; Nicotinamide Mononucleotide; Nucleotides; Senotherapeutics; Sirtuin 1

2023
NAD+ Precursors Nicotinamide Mononucleotide (NMN) and Nicotinamide Riboside (NR): Potential Dietary Contribution to Health.
    Current nutrition reports, 2023, Volume: 12, Issue:3

    Topics: Diet; Humans; NAD; Niacinamide; Nicotinamide Mononucleotide

2023

Trials

2 trial(s) available for nicotinamide mononucleotide and niacinamide

ArticleYear
Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men.
    Endocrine journal, 2020, Feb-28, Volume: 67, Issue:2

    Topics: Administration, Oral; Adult; Bilirubin; Blood Glucose; Blood Pressure; Body Temperature; Chlorides; Chromatography, Liquid; Creatinine; Diagnostic Techniques, Ophthalmological; Dose-Response Relationship, Drug; Electrocardiography; Healthy Volunteers; Heart Rate; Humans; Intraocular Pressure; Japan; Male; Middle Aged; Niacinamide; Nicotinamide Mononucleotide; Oxygen; Pyridones; Sleep; Tandem Mass Spectrometry; Visual Acuity

2020
The acute effect of different NAD
    Free radical biology & medicine, 2023, Aug-20, Volume: 205

    Topics: Humans; Metabolic Diseases; NAD; Neurodegenerative Diseases; Niacin; Niacinamide; Nicotinamide Mononucleotide

2023

Other Studies

90 other study(ies) available for nicotinamide mononucleotide and niacinamide

ArticleYear
Probing hot spots at protein-ligand binding sites: a fragment-based approach using biophysical methods.
    Journal of medicinal chemistry, 2006, Aug-10, Volume: 49, Issue:16

    Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Binding Sites; Biophysical Phenomena; Biophysics; Calorimetry; Escherichia coli; Ligands; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nucleotides; Protein Binding; Structure-Activity Relationship; Thermodynamics

2006
Inhibition of DNA synthesis in differentiating cardiac muscle by NAD.
    FEBS letters, 1976, Jan-15, Volume: 61, Issue:2

    Topics: Animals; Animals, Newborn; Biological Transport, Active; Cell Differentiation; DNA Replication; Female; Heart; Kinetics; Male; Myocardium; NAD; NADP; Niacinamide; Nicotinamide Mononucleotide; Pregnancy; Rats; Thymidine

1976
Effect of gangliosides and substrate analogues on the hydrolysis of nicotinamide adenine dinucleotide by choleragen.
    Proceedings of the National Academy of Sciences of the United States of America, 1977, Volume: 74, Issue:1

    Topics: Adenine; Adenine Nucleotides; Bacterial Toxins; Gangliosides; NAD; NAD+ Nucleosidase; NADP; Niacinamide; Nicotinamide Mononucleotide; Protein Conformation; Spectrometry, Fluorescence; Structure-Activity Relationship; Vibrio cholerae

1977
Characterization of a long-wavelength feature in the absorption and circular dichroism spectra of beta-nicotinamide adenine dinucleotide. Evidence for a charge transfer transition.
    Biochemistry, 1978, May-16, Volume: 17, Issue:10

    Topics: Circular Dichroism; Molecular Conformation; NAD; NADP; Niacinamide; Nicotinamide Mononucleotide; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Temperature

1978
Metabolism of niacin and niacinamide in perfused rat intestine.
    The Journal of nutrition, 1979, Volume: 109, Issue:4

    Topics: Animals; Biological Transport; Injections; Intestinal Absorption; Intestine, Small; Male; NAD; NAD+ Nucleosidase; NADP; Niacinamide; Nicotinamide Mononucleotide; Nicotinic Acids; Perfusion; Rats; Ribonucleotides; Time Factors

1979
Action of nucleotide phosphotransferase of Escherichia coli on nicotinamide riboside and nicotinamide mononucleotide.
    Proceedings of the National Academy of Sciences of the United States of America, 1977, Volume: 74, Issue:10

    Topics: Chemical Phenomena; Chemistry; Escherichia coli; Niacinamide; Nicotinamide Mononucleotide; Nucleotidyltransferases; Phosphates; Time Factors

1977
Pyridine nucleotide metabolism in mitotic cells.
    Journal of cellular physiology, 1975, Volume: 86 Suppl 2, Issue:3 Pt 2

    Topics: Cell Line; Colchicine; Kinetics; Mitosis; NAD; Niacinamide; Nicotinamide Mononucleotide; Nicotinic Acids

1975
Synthesis of pyridine nucleotides by mitochondrial fractions of yeast.
    Biochemical and biophysical research communications, 1976, May-23, Volume: 76, Issue:2

    Topics: Adenosine Triphosphate; Magnesium; Mitochondria; NAD; Niacinamide; Nicotinamide Mononucleotide; Nicotinic Acids; Phosphoribosyl Pyrophosphate; Saccharomyces cerevisiae; Sonication

1976
Kinetic alpha-deuterium isotope effects for enzymatic and nonenzymatic hydrolysis of nicotinamide-beta-riboside.
    Archives of biochemistry and biophysics, 1978, Volume: 191, Issue:2

    Topics: Animals; Brain; Deuterium; Escherichia coli; Hydrolysis; Kinetics; N-Glycosyl Hydrolases; NAD+ Nucleosidase; Niacinamide; Nicotinamide Mononucleotide; Pyridinium Compounds; Swine

1978
Pyridine nucleotide cycle of Salmonella typhimurium: regulation of nicotinic acid phosphoribosyltransferase and nicotinamide deamidase.
    Journal of bacteriology, 1979, Volume: 138, Issue:3

    Topics: Amidohydrolases; Enzyme Repression; Mutation; NAD; Niacinamide; Nicotinamidase; Nicotinamide Mononucleotide; Nicotinic Acids; Pentosyltransferases; Salmonella typhimurium

1979
Identification of novel reduced pyridinium derivatives as synthetic co-factors for the enzyme DT diaphorase (NAD(P)H dehydrogenase (quinone), EC 1.6.99.2).
    Biochemical pharmacology, 1992, Jul-07, Volume: 44, Issue:1

    Topics: Animals; Aziridines; Carcinoma 256, Walker; Coenzymes; Kinetics; NAD(P)H Dehydrogenase (Quinone); NADP; Niacinamide; Nicotinamide Mononucleotide; Oxidation-Reduction; Pyridinium Compounds; Rats; Structure-Activity Relationship; Vitamin K

1992
Activity of NMN+, nicotinamide ribose and analogs in alcohol oxidation promoted by horse-liver alcohol dehydrogenase. Improvement of this activity and structural requirements of the pyridine nucleotide part of the NAD+ coenzyme.
    European journal of biochemistry, 1986, Mar-03, Volume: 155, Issue:2

    Topics: Alcohol Dehydrogenase; Alcohol Oxidoreductases; Alcohols; Animals; Coenzymes; Horses; Kinetics; Liver; NAD; Niacinamide; Nicotinamide Mononucleotide; Oxidation-Reduction; Pyridinium Compounds; Structure-Activity Relationship

1986
Defining the metabolic and growth responses of porcine haemophili to exogenous pyridine nucleotides and precursors.
    Journal of general microbiology, 1986, Volume: 132, Issue:3

    Topics: Animals; Glucose; Haemophilus; NAD; NADP; Niacinamide; Nicotinamide Mononucleotide; Pyridinium Compounds; Swine

1986
Pyridine nucleotide metabolism by extracts derived from Haemophilus parasuis and H. pleuropneumoniae.
    Canadian journal of microbiology, 1986, Volume: 32, Issue:9

    Topics: Adenosine Triphosphate; Haemophilus; NAD; NADP; Niacinamide; Nicotinamide Mononucleotide; Pyridinium Compounds; Species Specificity

1986
Leucine excess and niacin status in rats.
    The Journal of nutrition, 1987, Volume: 117, Issue:3

    Topics: Animals; Body Weight; Diet; Edible Grain; India; Leucine; Liver; Male; Niacin; Niacinamide; Nicotinamide Mononucleotide; Nutritional Status; Pellagra; Rats; Rats, Inbred Strains; Statistics as Topic; Tryptophan; Vitamin B 6 Deficiency

1987
Biosynthesis of pyridine nucleotides in early embryos of the mouse (Mus musculus).
    The Journal of biological chemistry, 1973, Jul-25, Volume: 248, Issue:14

    Topics: Animals; Azaserine; Carbon Isotopes; Chorionic Gonadotropin; Embryo Implantation; Embryo, Mammalian; Embryonic and Fetal Development; Female; Fertilization; Humans; Male; Mice; Mitosis; NAD; NADP; Niacinamide; Nicotinamide Mononucleotide; Nicotinic Acids; Ovum; Pregnancy; Pyridines

1973
Effects of leucine and isoleucine on nicotinamide nucleotides of erythrocytes.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1973, Volume: 43, Issue:4

    Topics: Adult; Blood Glucose; Carbon Dioxide; Carbon Radioisotopes; Drug Synergism; Erythrocytes; Feces; Glycolysis; Humans; Isoleucine; Lactates; Leucine; Male; NAD; NADP; Niacinamide; Nicotinamide Mononucleotide; Oxidation-Reduction; Pyridines; Ribonucleotides; Time Factors

1973
Natural abundance 13C nuclear magnetic resonance spectra of nicotinamide adenine dinucleotide and related nucleotides.
    Biochemistry, 1973, Sep-11, Volume: 12, Issue:19

    Topics: Adenosine Monophosphate; Carbon Isotopes; Chemical Phenomena; Chemistry; Magnetic Resonance Spectroscopy; Molecular Conformation; NAD; NADP; Niacinamide; Nicotinamide Mononucleotide; Oxidation-Reduction; Protons; Ribose; Time Factors

1973
The biosynthesis and turnover of nicotinamide adenine dinucleotide in enucleated culture cells.
    Journal of cellular physiology, 1974, Volume: 84, Issue:3

    Topics: Autoradiography; Azaserine; Bone Marrow; Bone Marrow Cells; Cell Fractionation; Cell Line; Cell Nucleus; Cells, Cultured; Chromatography, Paper; Microsomes; N-Glycosyl Hydrolases; NAD; NADP; Niacinamide; Nicotinamide Mononucleotide; Nicotinic Acids; Tritium

1974
Effect of the inhibitors on the nicotinamide nucleotides level in isolated chloroplasts.
    Bulletin de l'Academie polonaise des sciences. Serie des sciences biologiques, 1973, Volume: 21, Issue:7

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Chlorophyll; Chloroplasts; Electron Transport; Niacinamide; Nicotinamide Mononucleotide; Ribonucleotides; Vegetables

1973
Evidence for an active site persulfide residue in rabbit liver aldehyde oxidase.
    The Journal of biological chemistry, 1974, Jul-25, Volume: 249, Issue:14

    Topics: Aldehyde Oxidoreductases; Anaerobiosis; Animals; Binding Sites; Carbon Radioisotopes; Catalysis; Cyanides; Flavin-Adenine Dinucleotide; Kinetics; Liver; Niacinamide; Nicotinamide Mononucleotide; Oxidation-Reduction; Oxygen; Potassium; Rabbits; Spectrophotometry; Sulfides

1974
Pyridine nucleotide synthesis. Purification of nicotinamide mononucleotide pyrophosphorylase from rat erythrocytes.
    The Journal of biological chemistry, 1972, Dec-25, Volume: 247, Issue:24

    Topics: Adenosine Triphosphate; Ammonium Sulfate; Animals; Carbon Isotopes; Chromatography, DEAE-Cellulose; Drug Stability; Edetic Acid; Erythrocytes; Hemolysis; Hydrogen-Ion Concentration; Kinetics; Magnesium; N-Glycosyl Hydrolases; NAD; Niacinamide; Nicotinamide Mononucleotide; Nicotinic Acids; Nucleotidyltransferases; Pentosephosphates; Phosphoric Acids; Rats

1972
Pyridinium precursors of pyridine nucleotides in perfused rat kidney and in the testis.
    The Journal of biological chemistry, 1972, Dec-25, Volume: 247, Issue:24

    Topics: Adenosine Triphosphate; Amidohydrolases; Animals; Carbon Isotopes; Kidney; Male; N-Glycosyl Hydrolases; NAD; Niacinamide; Nicotinamide Mononucleotide; Nicotinic Acids; Nucleotidyltransferases; Perfusion; Pyridines; Pyridinium Compounds; Rats; Testis; Uric Acid

1972
Metabolism of pyridine nucleotides and its relation to DNA synthesis in regenerating mouse liver.
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1972, Volume: 353, Issue:12

    Topics: Adenine Nucleotides; Animals; DNA; Female; Hepatectomy; Hydrolases; Kynurenine; Liver; Liver Regeneration; Mice; Mice, Inbred Strains; NAD; Niacinamide; Nicotinamide Mononucleotide; Nucleotidyltransferases; ortho-Aminobenzoates; Pentosyltransferases; Transaminases; Tryptophan

1972
Biosynthesis of NAD in Haemophilus haemoglobinophilus.
    Biochimica et biophysica acta, 1973, Sep-14, Volume: 320, Issue:2

    Topics: Carbon Radioisotopes; Chromatography, Paper; Electrophoresis, Paper; Haemophilus; NAD; Niacinamide; Nicotinamide Mononucleotide; Nicotinic Acids; Pentosyltransferases; Pyridines; Ribose

1973
Biliary excretion of nicotinamide riboside. A possible role in the regulation of hepatic pyridine nucleotide dynamics.
    Biochemical pharmacology, 1973, Nov-01, Volume: 22, Issue:21

    Topics: Animals; Bile; Carbon Radioisotopes; Chromatography, Gel; Chromatography, Paper; Electrophoresis, Paper; Female; Fluorometry; Freeze Drying; Liver; Methylation; NAD; Niacinamide; Nicotinamide Mononucleotide; Nicotinic Acids; Rats; Ribonucleosides; Time Factors

1973
The equilibria and reaction rates of nicotinamide-adenine dinucleotide and its related compounds with cyanide ion in the presence of polyelectrolytes.
    The Journal of biological chemistry, 1974, Jun-10, Volume: 249, Issue:11

    Topics: Allyl Compounds; Chemical Phenomena; Chemistry; Cyanides; DNA; Kinetics; NAD; Niacinamide; Nicotinamide Mononucleotide; Polymers; Polynucleotides; Polyvinyls; Pyridinium Compounds; Quaternary Ammonium Compounds; Ribonucleotides; Surface-Active Agents; Thermodynamics

1974
A Raman and infrared spectroscopic study of the 3-carbonyl group of pyridine nucleotide coenzymes and related model compounds.
    Biochemistry, 1974, Jul-02, Volume: 13, Issue:14

    Topics: Acetates; Aldehydes; Chemical Phenomena; Chemistry; Coenzymes; Deuterium; Dioxins; Drug Stability; Models, Chemical; NAD; Niacinamide; Nicotinamide Mononucleotide; Nicotinic Acids; Oxidation-Reduction; Pyridines; Ribonucleotides; Spectrophotometry, Infrared; Spectrum Analysis

1974
Simple methods of preparing nicotinamide mononucleotide.
    FEBS letters, 1974, Jun-01, Volume: 42, Issue:2

    Topics: Animals; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis; Evaluation Studies as Topic; Horses; L-Lactate Dehydrogenase; Methods; NAD; Niacinamide; Nicotinamide Mononucleotide; Plants; Pyrophosphatases; Ribonucleotides; Spectrophotometry, Ultraviolet

1974
Bull semen nicotinamide adenine dinucleotide nucleosidase. V. Kinetic studies.
    The Journal of biological chemistry, 1973, Jan-25, Volume: 248, Issue:2

    Topics: Adenine Nucleotides; Aldehydes; Animals; Binding, Competitive; Catalysis; Cattle; Drug Stability; Feedback; Hydrolysis; Hypoxanthines; Kinetics; Male; Mathematics; N-Glycosyl Hydrolases; NAD; NADP; Niacinamide; Nicotinamide Mononucleotide; Nucleotides; Pyridines; Ribonucleotides; Semen; Structure-Activity Relationship; Sulfides

1973
Crystallographic investigations of nicotinamide adenine dinucleotide binding to horse liver alcohol dehydrogenase.
    Biochemistry, 1984, Dec-04, Volume: 23, Issue:25

    Topics: Adenine; Adenosine Diphosphate Ribose; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Binding Sites; Chemical Phenomena; Chemistry, Physical; Crystallography; Diphosphates; Liver; Molecular Conformation; NAD; Niacinamide; Nicotinamide Mononucleotide; Protein Conformation; Ribose

1984
Nucleoside salvage pathway for NAD biosynthesis in Salmonella typhimurium.
    Journal of bacteriology, 1982, Volume: 152, Issue:3

    Topics: NAD; Niacinamide; Nicotinamide Mononucleotide; Phosphorylation; Pyridinium Compounds; Salmonella typhimurium

1982
Reactivation of NAD(H) biosynthetic pathway by exogenous NAD+ in Nil cells severely depleted of NAD(H).
    Journal of cellular physiology, 1983, Volume: 114, Issue:2

    Topics: Animals; Cell Division; Cell Line; Cricetinae; DNA; Fibroblasts; Glucose; Interphase; Lactates; Lactic Acid; NAD; Niacin; Niacinamide; Nicotinamide Mononucleotide; Protein Biosynthesis

1983
Isoniazid perturbation of the pyridine nucleotide cycle of Escherichia coli.
    Microbios, 1982, Volume: 35, Issue:141-142

    Topics: Escherichia coli; Isoniazid; Mutation; NAD; NADP; Niacin; Niacinamide; Nicotinamide Mononucleotide

1982
Apparent pyridine nucleotide synthesis in mitochondria: an artifact of NMN and NAD glycohydrolase activity?
    Biochemical and biophysical research communications, 1981, Aug-14, Volume: 101, Issue:3

    Topics: Animals; Female; In Vitro Techniques; Microsomes, Liver; Mitochondria, Liver; N-Glycosyl Hydrolases; NAD; NAD+ Nucleosidase; Niacinamide; Nicotinamide Mononucleotide; Rats

1981
Pyridine nucleotide metabolism in the erythrocyte of South African blacks with primary hepatoma.
    Acta vitaminologica et enzymologica, 1982, Volume: 4, Issue:3

    Topics: Black People; Carcinoma, Hepatocellular; Erythrocytes; Humans; Liver Neoplasms; Models, Biological; NAD; NADP; Niacin; Niacinamide; Nicotinamide Mononucleotide; South Africa

1982
Preliminary evidence for a pyridine nucleotide cycle in Bordetella pertussis.
    Antonie van Leeuwenhoek, 1984, Volume: 50, Issue:1

    Topics: Bordetella pertussis; NAD; Niacin; Niacinamide; Nicotinamidase; Nicotinamide Mononucleotide

1984
Pyridine nucleotide cycle of Salmonella typhimurium: in vivo recycling of nicotinamide adenine dinucleotide.
    Journal of bacteriology, 1980, Volume: 142, Issue:3

    Topics: Amidohydrolases; Mutation; N-Glycosyl Hydrolases; NAD; Niacinamide; Nicotinamidase; Nicotinamide Mononucleotide; Nicotinic Acids; Salmonella typhimurium

1980
A rapid procedure for assaying nicotinamide phosphoribosyltransferase.
    Analytical biochemistry, 1980, Sep-01, Volume: 107, Issue:1

    Topics: Acetone; Animals; Chromatography, Paper; Liver; Mice; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Nicotinic Acids; Pentosyltransferases; Solubility; Ultrafiltration

1980
A new physiological biomarker for nitrate exposure in humans.
    Toxicology letters, 1995, Volume: 77, Issue:1-3

    Topics: Animals; Biomarkers; Chromatography, High Pressure Liquid; Environmental Monitoring; Environmental Pollutants; Female; Humans; Male; Niacinamide; Nicotinamide Mononucleotide; Nitrates; Nitrites; Rats; Rats, Inbred Strains

1995
Fluorescence of reduced nicotinamides using one- and two-photon excitation.
    Biophysical chemistry, 1996, Nov-29, Volume: 62, Issue:1-3

    Topics: Absorptiometry, Photon; Anisotropy; Fluorescence; Fluorescent Dyes; NAD; Niacinamide; Nicotinamide Mononucleotide; Oxidation-Reduction; Spectrometry, Fluorescence

1996
Determining NAD synthesis in erythrocytes.
    Methods in enzymology, 1997, Volume: 280

    Topics: Adenine Nucleotides; Amide Synthases; Chromatography, High Pressure Liquid; Erythrocytes; Humans; Ligases; NAD; Niacin; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Nicotinamide-Nucleotide Adenylyltransferase; Nucleotidyltransferases; Pentosyltransferases

1997
Detection and identification of NAD-catabolizing activities in rat tissue homogenates.
    Biochimica et biophysica acta, 1997, Jun-20, Volume: 1340, Issue:1

    Topics: Adenosine Diphosphate Ribose; Adenosine Monophosphate; Animals; Detergents; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Kidney Cortex; Male; Molecular Weight; NAD; NAD+ Nucleosidase; Niacinamide; Nicotinamide Mononucleotide; Pyrophosphatases; Rats; Rats, Wistar; Spleen; Zinc

1997
The reaction mechanism for CD38. A single intermediate is responsible for cyclization, hydrolysis, and base-exchange chemistries.
    Biochemistry, 1998, Sep-22, Volume: 37, Issue:38

    Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Antigens, Differentiation; Binding, Competitive; Catalysis; Cyclic ADP-Ribose; Fluorescence Polarization; Guanosine Diphosphate Sugars; Humans; Hydrolysis; Kinetics; Membrane Glycoproteins; Methanol; NAD; NAD+ Nucleosidase; Niacinamide; Nicotinamide Mononucleotide; Spectrometry, Fluorescence; Substrate Specificity

1998
On the irreversible destruction of reduced nicotinamide nucleotides by hypohalous acids.
    Archives of biochemistry and biophysics, 2000, Aug-01, Volume: 380, Issue:1

    Topics: Bromates; Chlorates; Hydrogen-Ion Concentration; Iodine Compounds; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; NAD; Niacinamide; Nicotinamide Mononucleotide; Oxidation-Reduction; Oxygen; Pyridines; Time Factors

2000
NadN and e (P4) are essential for utilization of NAD and nicotinamide mononucleotide but not nicotinamide riboside in Haemophilus influenzae.
    Journal of bacteriology, 2001, Volume: 183, Issue:13

    Topics: Bacterial Outer Membrane Proteins; Bacterial Proteins; Biological Transport; Esterases; Haemophilus influenzae; Lipoproteins; Models, Biological; Multienzyme Complexes; NAD; Niacinamide; Nicotinamide Mononucleotide; Nucleotidases; Pyridinium Compounds; Pyrophosphatases

2001
RNA aptamers that bind flavin and nicotinamide redox cofactors.
    Journal of the American Chemical Society, 1995, Feb-01, Volume: 117, Issue:4

    Topics: Base Sequence; Binding Sites; Evolution, Molecular; Guanosine; NAD; NADP; Niacinamide; Nicotinamide Mononucleotide; Oxidation-Reduction; Riboflavin; RNA; Sequence Analysis, RNA; Uridine

1995
Crystallographic studies on human BST-1/CD157 with ADP-ribosyl cyclase and NAD glycohydrolase activities.
    Journal of molecular biology, 2002, Feb-22, Volume: 316, Issue:3

    Topics: Adenosine Triphosphate; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Amino Acid Sequence; Antigens, CD; Antigens, Differentiation; Binding Sites; Catalysis; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Dimerization; Disulfides; GPI-Linked Proteins; Humans; Ligands; Membrane Glycoproteins; Models, Chemical; Models, Molecular; Molecular Sequence Data; NAD; NAD+ Nucleosidase; NADP; Niacinamide; Nicotinamide Mononucleotide; Protein Binding; Protein Structure, Quaternary; Protein Structure, Tertiary; Sequence Alignment; Substrate Specificity

2002
[Influence of human erythrocytes on the synthesis of nicotinamide mononucleotide in vitro].
    Clinica chimica acta; international journal of clinical chemistry, 1962, Volume: 7

    Topics: Coenzymes; Erythrocytes; Humans; In Vitro Techniques; Niacinamide; Nicotinamide Mononucleotide

1962
Nicotinamide mononucleotide activation of new DNA-dependent polyadenylic acid synthesizing nuclear enzyme.
    Biochemical and biophysical research communications, 1963, Apr-02, Volume: 11

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Cell Nucleus; DNA; Liver; Metabolism; Niacin; Niacinamide; Nicotinamide Mononucleotide; Nucleotides; Poly A

1963
Synthesis of nicotinamide mononucleotide by human erythrocytes in vitro.
    The Journal of biological chemistry, 1951, Volume: 189, Issue:2

    Topics: Erythrocytes; Humans; In Vitro Techniques; Niacin; Niacinamide; Nicotinamide Mononucleotide

1951
NAD deamidation "a new reaction" by an enzyme from Aspergillus terreus DSM 826.
    Antonie van Leeuwenhoek, 2005, Volume: 87, Issue:2

    Topics: Acetamides; Acrylic Resins; Asparagine; Aspergillus; Chromatography, Liquid; Deamination; Enzyme Inhibitors; Enzyme Stability; Freezing; Glutamine; Hydrogen-Ion Concentration; Kinetics; NAD; Niacinamide; Nicotinamide Mononucleotide; Pyridinium Compounds; Substrate Specificity; Temperature

2005
Assimilation of nicotinamide mononucleotide requires periplasmic AphA phosphatase in Salmonella enterica.
    Journal of bacteriology, 2005, Volume: 187, Issue:13

    Topics: Acid Phosphatase; Bacterial Proteins; Membrane Transport Proteins; Mutation; Niacinamide; Nicotinamide Mononucleotide; Periplasm; Pyridines; Pyridinium Compounds; Repressor Proteins; Salmonella enterica

2005
The simultaneous measurement of nicotinamide adenine dinucleotide and related compounds by liquid chromatography/electrospray ionization tandem mass spectrometry.
    Analytical biochemistry, 2006, May-15, Volume: 352, Issue:2

    Topics: Adenosine Diphosphate Ribose; Adenosine Monophosphate; Animals; Chromatography, Liquid; Erythrocytes; HL-60 Cells; Humans; Mice; Mice, Inbred BALB C; NAD; Niacin; Niacinamide; Nicotinamide Mononucleotide; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization

2006
Comparative genomics of NAD biosynthesis in cyanobacteria.
    Journal of bacteriology, 2006, Volume: 188, Issue:8

    Topics: Amide Synthases; Cyanobacteria; Escherichia coli; Gene Transfer, Horizontal; Genome, Bacterial; Glutamine; Models, Biological; Multigene Family; NAD; Niacin; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Nucleotidyltransferases; Pentosyltransferases; Synteny

2006
Nicotinamidase participates in the salvage pathway of NAD biosynthesis in Arabidopsis.
    The Plant journal : for cell and molecular biology, 2007, Volume: 49, Issue:6

    Topics: Arabidopsis; Gene Expression; Metabolic Networks and Pathways; NAD; NADP; Niacinamide; Nicotinamidase; Nicotinamide Mononucleotide; Nicotinic Acids; Plant Roots

2007
Detection and pharmacological modulation of nicotinamide mononucleotide (NMN) in vitro and in vivo.
    Biochemical pharmacology, 2009, May-15, Volume: 77, Issue:10

    Topics: Acetophenones; Acrylamides; Animals; Cell Survival; Chromatography, High Pressure Liquid; Cytokines; Enzyme Inhibitors; Formates; HeLa Cells; Humans; Male; Mice; NAD; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Organ Specificity; Piperidines; U937 Cells

2009
Identification of Isn1 and Sdt1 as glucose- and vitamin-regulated nicotinamide mononucleotide and nicotinic acid mononucleotide [corrected] 5'-nucleotidases responsible for production of nicotinamide riboside and nicotinic acid riboside.
    The Journal of biological chemistry, 2009, Dec-11, Volume: 284, Issue:50

    Topics: 5'-Nucleotidase; Gene Knockout Techniques; Glucose; NAD; Niacin; Niacinamide; Nicotinamide Mononucleotide; Pyridinium Compounds; Ribonucleosides; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Vitamins

2009
Characterization of human nicotinate phosphoribosyltransferase: Kinetic studies, structure prediction and functional analysis by site-directed mutagenesis.
    Biochimie, 2012, Volume: 94, Issue:2

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Cloning, Molecular; Enzyme Activation; Escherichia coli; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Niacin; Niacinamide; Nicotinamide Mononucleotide; Pentosyltransferases; Plasmids; Recombinant Proteins; Structural Homology, Protein; Sugar Phosphates

2012
Nicotinamide phosphoribosyltransferase/visfatin does not catalyze nicotinamide mononucleotide formation in blood plasma.
    PloS one, 2011, Volume: 6, Issue:8

    Topics: Animals; Humans; Mice; Mice, Inbred C57BL; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Organophosphorus Compounds; Plasma

2011
Comparison of the formation of nicotinic acid conjugates in leaves of different plant species.
    Plant physiology and biochemistry : PPB, 2012, Volume: 60

    Topics: Alkaloids; Carbon Radioisotopes; Embryophyta; Glucosides; NAD; Niacin; Niacinamide; Nicotinamide Mononucleotide; Plant Leaves; Species Specificity; Time Factors

2012
NAMPT/PBEF1 enzymatic activity is indispensable for myeloma cell growth and osteoclast activity.
    Experimental hematology, 2013, Volume: 41, Issue:6

    Topics: Acrylamides; Animals; Bone and Bones; Cell Differentiation; Coculture Techniques; Cytokines; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Mice; Mice, SCID; Multiple Myeloma; NAD; Neoplasm Proteins; NF-kappa B; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Osteoclasts; Osteolysis; Piperidines; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Rabbits; Sirtuin 1; Tumor Cells, Cultured; Up-Regulation

2013
Discovery of a novel nicotinamide phosphoribosyl transferase (NAMPT) inhibitor via in silico screening.
    Biological & pharmaceutical bulletin, 2014, Volume: 37, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Computer Simulation; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; K562 Cells; Leukemia; Mice; NAD; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase

2014
PARPs and ADP-Ribosylation: 50 Years … and Counting.
    Molecular cell, 2015, Jun-18, Volume: 58, Issue:6

    Topics: Adenosine Diphosphate Ribose; Biomedical Research; Biosynthetic Pathways; Forecasting; Humans; Interviews as Topic; Molecular Structure; NAD; Niacinamide; Nicotinamide Mononucleotide; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Protein Processing, Post-Translational; Time Factors

2015
Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model.
    Oncotarget, 2016, Jan-19, Volume: 7, Issue:3

    Topics: 5'-Nucleotidase; Acrylamides; Adenosine Triphosphate; Animals; Cell Line, Tumor; Cytokines; Female; GPI-Linked Proteins; Humans; Mice; Mice, Nude; NAD; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Ovarian Neoplasms; Piperidines; Pyridinium Compounds; RNA Interference; RNA, Small Interfering

2016
Auxotrophic Actinobacillus pleurpneumoniae grows in multispecies biofilms without the need for nicotinamide-adenine dinucleotide (NAD) supplementation.
    BMC microbiology, 2016, 06-27, Volume: 16, Issue:1

    Topics: Acetylglucosamine; Actinobacillus Infections; Actinobacillus pleuropneumoniae; Animals; Biofilms; Bordetella bronchiseptica; Culture Media; Deoxyribonuclease I; Endopeptidase K; Escherichia coli; In Situ Hybridization, Fluorescence; Microscopy, Confocal; NAD; Niacinamide; Nicotinamide Mononucleotide; Pasteurella multocida; Pyridines; Pyridinium Compounds; Species Specificity; Staphylococcus aureus; Stem Cells; Streptococcus suis; Swine; Swine Diseases

2016
Nicotinamide mononucleotide inhibits post-ischemic NAD(+) degradation and dramatically ameliorates brain damage following global cerebral ischemia.
    Neurobiology of disease, 2016, Volume: 95

    Topics: Animals; Brain Injuries; Brain Ischemia; Cell Death; Disease Models, Animal; Hippocampus; Male; Mice, Inbred C57BL; NAD; Niacinamide; Nicotinamide Mononucleotide

2016
β-Nicotinamide Mononucleotide, an Anti-Aging Candidate Compound, Is Retained in the Body for Longer than Nicotinamide in Rats.
    Journal of nutritional science and vitaminology, 2016, Volume: 62, Issue:4

    Topics: Aging; Animals; Injections, Intraperitoneal; Longevity; Male; NAD; Niacinamide; Nicotinamide Mononucleotide; Rats; Rats, Wistar

2016
NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells.
    Nature communications, 2016, 10-11, Volume: 7

    Topics: Animals; Hep G2 Cells; Hepatocytes; Humans; Injections, Intraperitoneal; Mammals; Mice, Knockout; NAD; Niacinamide; Nicotinamide Mononucleotide; Phosphotransferases (Alcohol Group Acceptor); Pyridinium Compounds

2016
Simultaneous quantitation of nicotinamide riboside, nicotinamide mononucleotide and nicotinamide adenine dinucleotide in milk by a novel enzyme-coupled assay.
    Food chemistry, 2017, Apr-15, Volume: 221

    Topics: Animals; Cattle; Enzyme Assays; Equidae; Fluorometry; Food Analysis; Food Handling; Humans; Milk; Milk, Human; NAD; Niacinamide; Nicotinamide Mononucleotide; Pasteurization; Pyridinium Compounds

2017
Hyperthermophilic Archaeon Thermococcus kodakarensis Utilizes a Four-Step Pathway for NAD
    Journal of bacteriology, 2018, 06-01, Volume: 200, Issue:11

    Topics: Deamination; Hot Temperature; NAD; Niacinamide; Nicotinamidase; Nicotinamide Mononucleotide; Nicotinic Acids; Nucleotidyltransferases; Pentosyltransferases; Recombinant Proteins; Substrate Specificity; Thermococcus

2018
Nicotinamide adenine dinucleotide is transported into mammalian mitochondria.
    eLife, 2018, 06-12, Volume: 7

    Topics: Animals; Biological Transport; Cell Line; HEK293 Cells; HL-60 Cells; Humans; Male; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Mitochondria, Muscle; Myoblasts; NAD; Niacinamide; Nicotinamide Mononucleotide; Pyridinium Compounds

2018
Pharmacological bypass of NAD
    Proceedings of the National Academy of Sciences of the United States of America, 2018, 10-16, Volume: 115, Issue:42

    Topics: Acrylamides; Animals; Antineoplastic Agents, Phytogenic; Drug Combinations; Francisella tularensis; Ganglia, Spinal; NAD; Nerve Degeneration; Neurons; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Piperidines; Pyridinium Compounds; Vincristine

2018
Enhanced SIRT6 activity abrogates the neurotoxic phenotype of astrocytes expressing ALS-linked mutant SOD1.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019, Volume: 33, Issue:6

    Topics: Animals; Antioxidant Response Elements; Astrocytes; Gene Expression Regulation; Mice; Mutation; Niacinamide; Nicotinamide Mononucleotide; Pyridinium Compounds; Sirtuins; Superoxide Dismutase-1

2019
Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway.
    Cell metabolism, 2020, 03-03, Volume: 31, Issue:3

    Topics: Administration, Oral; Amides; Animals; Biosynthetic Pathways; Cell Line, Tumor; Cytokines; Energy Metabolism; Female; Gastrointestinal Microbiome; Humans; Male; Mammals; Metabolome; Mice, Inbred C57BL; Mycoplasma; NAD; Niacinamide; Nicotinamidase; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Pyridinium Compounds

2020
Reversal of endothelial dysfunction by nicotinamide mononucleotide via extracellular conversion to nicotinamide riboside.
    Biochemical pharmacology, 2020, Volume: 178

    Topics: 5'-Nucleotidase; Animals; Cell Line; Endothelial Cells; Extracellular Fluid; Female; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Niacinamide; Nicotinamide Mononucleotide; Pyridinium Compounds

2020
Physical exercise may exert its therapeutic influence on Alzheimer's disease through the reversal of mitochondrial dysfunction via SIRT1-FOXO1/3-PINK1-Parkin-mediated mitophagy.
    Journal of sport and health science, 2021, Volume: 10, Issue:1

    Topics: Adenosine Triphosphate; Alzheimer Disease; Amyloid beta-Peptides; Brain-Derived Neurotrophic Factor; Disease Progression; Exercise; Forkhead Box Protein O1; Humans; Mitochondria; Mitochondrial Diseases; Mitophagy; NAD; Niacinamide; Nicotinamide Mononucleotide; Protein Kinases; Pyridinium Compounds; Reactive Oxygen Species; Sirtuin 1; Ubiquitin-Protein Ligases

2021
Metabolic design for selective production of nicotinamide mononucleotide from glucose and nicotinamide.
    Metabolic engineering, 2021, Volume: 65

    Topics: Biosynthetic Pathways; Escherichia coli; Glucose; NAD; Niacinamide; Nicotinamide Mononucleotide

2021
Equilibrative Nucleoside Transporters Mediate the Import of Nicotinamide Riboside and Nicotinic Acid Riboside into Human Cells.
    International journal of molecular sciences, 2021, Jan-30, Volume: 22, Issue:3

    Topics: Aging; Cytosol; Equilibrative Nucleoside Transport Proteins; HEK293 Cells; Humans; Magnetic Resonance Spectroscopy; Membrane Transport Proteins; Metabolomics; NAD; Niacinamide; Nicotinamide Mononucleotide; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Pyridinium Compounds; Recombinant Proteins; Ribonucleosides

2021
Nicotinamide mononucleotide production by fructophilic lactic acid bacteria.
    Scientific reports, 2021, 04-07, Volume: 11, Issue:1

    Topics: Escherichia coli; Fructose; Lactobacillales; Leuconostoc; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Pyridinium Compounds

2021
Creating enzymes and self-sufficient cells for biosynthesis of the non-natural cofactor nicotinamide cytosine dinucleotide.
    Nature communications, 2021, 04-09, Volume: 12, Issue:1

    Topics: Coenzymes; Cytidine Triphosphate; Enzyme Assays; Escherichia coli; Escherichia coli Proteins; High-Throughput Screening Assays; Lactic Acid; Malates; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide-Nucleotide Adenylyltransferase; Oxidation-Reduction; Protein Engineering; Substrate Specificity; Synthetic Biology

2021
Metabolic engineering of Escherichia coli for biosynthesis of β-nicotinamide mononucleotide from nicotinamide.
    Microbial biotechnology, 2021, Volume: 14, Issue:6

    Topics: Escherichia coli; Metabolic Engineering; NAD; Niacinamide; Nicotinamide Mononucleotide

2021
Biosynthesis of a Therapeutically Important Nicotinamide Mononucleotide through a Phosphoribosyl Pyrophosphate Synthetase 1 and 2 Engineered Strain of
    ACS synthetic biology, 2021, 11-19, Volume: 10, Issue:11

    Topics: Biosynthetic Pathways; Escherichia coli; Glucose; Metabolic Engineering; NAD; Niacinamide; Nicotinamide Mononucleotide; Nucleotides; Ribose-Phosphate Pyrophosphokinase

2021
    JAMA health forum, 2021, Volume: 2, Issue:11

    Topics: Aged; Animals; Antipsychotic Agents; Arabinose; Cell Wall; Cohort Studies; Crystallography, X-Ray; Cytochrome P-450 Enzyme System; Dimyristoylphosphatidylcholine; Electron Transport; Escherichia coli; Female; Ferroptosis; Fibroblasts; Flour; Humans; Indicators and Reagents; Inulin; Ligands; Lipid Bilayers; Lipid Peroxidation; Magnetic Resonance Spectroscopy; Medicare; Membrane Proteins; Mice; NAD; NADPH-Ferrihemoprotein Reductase; Nanostructures; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Nursing Homes; Pain; Palladium; Phospholipids; Pressure Ulcer; Spectroscopy, Fourier Transform Infrared; Sulfhydryl Compounds; Triticum; United States; Water; Xylans; Xylose

2021
An artificial multi-enzyme cascade biocatalysis for biomanufacturing of nicotinamide mononucleotide from starch and nicotinamide in one-pot.
    Enzyme and microbial technology, 2023, Volume: 162

    Topics: Biocatalysis; NAD; Niacinamide; Nicotinamide Mononucleotide; Prospective Studies; Starch

2023
Enhancing the biosynthesis of nicotinamide mononucleotide in Lactococcus lactis by heterologous expression of FtnadE.
    Journal of the science of food and agriculture, 2023, Jan-15, Volume: 103, Issue:1

    Topics: Lactococcus lactis; NAD; Niacinamide; Nicotinamide Mononucleotide

2023
Nicotinamide mononucleotides alleviated neurological impairment via anti-neuroinflammation in traumatic brain injury.
    International journal of medical sciences, 2023, Volume: 20, Issue:3

    Topics: Animals; Brain Injuries, Traumatic; NAD; Niacinamide; Nicotinamide Mononucleotide; Rats; Toll-Like Receptor 2

2023
NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency.
    Cell reports, 2023, 05-30, Volume: 42, Issue:5

    Topics: Autophagy; Humans; Mitochondria; NAD; Neurons; Niacinamide; Nicotinamide Mononucleotide

2023
Identification of structural determinants of nicotinamide phosphoribosyl transferase (NAMPT) activity and substrate selectivity.
    Journal of structural biology, 2023, Volume: 215, Issue:3

    Topics: Animals; Kinetics; Mammals; NAD; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Phosphorylation

2023
A holistic approach for process intensification of nicotinamide mononucleotide production via high cell density cultivation under exponential feeding strategy.
    Bioresource technology, 2023, Volume: 390

    Topics: Batch Cell Culture Techniques; Bioreactors; Glucose; NAD; Niacinamide; Nicotinamide Mononucleotide

2023