Page last updated: 2024-08-21

nicotinamide mononucleotide and fk 866

nicotinamide mononucleotide has been researched along with fk 866 in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (31.25)29.6817
2010's11 (68.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Eom, SH; Kang, GB; Kim, H; Kim, JB; Kim, KK; Kim, MK; Kim, SH; Lee, JH; Lee, YS; Park, SJ; Suh, SW1
Cha, DR; Han, JY; Han, KH; Han, SY; Kang, YS; Kim, BK; Kim, HK; Ko, GJ; Lee, MH; Park, YG; Song, HK1
Burgos, ES; Schramm, VL1
Brunkan, CS; Cui, D; Dorweiler, B; Imai, S; Li, Y; Tabas, I; Wang, T; Wolberger, C; Woo, CW; Zhang, Y1
Chiarugi, A; Formentini, L; Moroni, F1
Bam, R; Barlogie, B; Epstein, J; Khan, S; Li, X; Ling, W; Usmani, S; van Rhee, F; Venkateshaiah, SU; Yaccoby, S1
Bruzzone, S; Caffa, I; De Flora, A; Grozio, A; Nencioni, A; Raffaelli, N; Salis, A; Sociali, G; Soncini, D; Sturla, L1
Jiang, WX; Lu, JT; Lu, YB; Tang, C; Wei, EQ; Wu, M; Zhang, WP; Zhang, XQ1
Lavandero, S; López-Crisosto, C; Oyarzún, AP; Parra, V; Pedrozo, Z; Pennanen, C; Sánchez, G; Sotomayor-Flores, C; Troncoso, R; Westermeier, F1
Bianchi, G; Bruzzone, S; Emionite, L; Magnone, M; Nahimana, A; Nencioni, A; Raffaelli, N; Raffaghello, L; Sociali, G; Sturla, L; Vigliarolo, T; Zamporlini, F1
Conforti, L; Di Stefano, M; Gering, M; Loreto, A1
Guo, SQ; Hu, ZW; Li, WL; Zou, XD1
Deng, KY; Guan, XH; Hu, L; Huang, CC; Qian, YS; Wang, LF; Wang, XN; Xiao, YF; Xin, HB1
Garten, A; Gebhardt, R; Gorski, T; Kiess, W; Penke, M; Schuster, S1
Bartoli, M; Fuller, J; Jadeja, RN; Jones, MA; Joseph, E; Martin, PM; Powell, FL; Thounaojam, MC1
Brenner, C; Cambronne, XA; Cohen, MS; Goodman, RH; Liu, HW; Migaud, ME; Schmidt, MS; Smith, CB1

Other Studies

16 other study(ies) available for nicotinamide mononucleotide and fk 866

ArticleYear
Crystal structure of visfatin/pre-B cell colony-enhancing factor 1/nicotinamide phosphoribosyltransferase, free and in complex with the anti-cancer agent FK-866.
    Journal of molecular biology, 2006, Sep-08, Volume: 362, Issue:1

    Topics: Acrylamides; Amino Acid Sequence; Animals; Antineoplastic Agents; Binding Sites; Crystallography, X-Ray; Cytokines; Dimerization; Humans; Molecular Sequence Data; Molecular Structure; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Piperidines; Protein Structure, Quaternary; Protein Structure, Tertiary; Rats; Sequence Homology

2006
Visfatin: a new player in mesangial cell physiology and diabetic nephropathy.
    American journal of physiology. Renal physiology, 2008, Volume: 295, Issue:5

    Topics: Acrylamides; Adipocytes, White; Angiotensin II; Animals; Blotting, Western; Cell Survival; Cells, Cultured; Collagen Type I; Cytokines; Diabetic Nephropathies; Gene Expression; Glucose; Glucose Transporter Type 1; Mesangial Cells; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Phosphorylation; Piperidines; Plasminogen Activator Inhibitor 1; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Transforming Growth Factor beta1

2008
Weak coupling of ATP hydrolysis to the chemical equilibrium of human nicotinamide phosphoribosyltransferase.
    Biochemistry, 2008, Oct-21, Volume: 47, Issue:42

    Topics: Acrylamides; Adenosine Triphosphate; Cytokines; Enzyme Inhibitors; Enzyme Stability; Humans; Hydrolysis; In Vitro Techniques; Kinetics; Models, Biological; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Phosphorylation; Piperidines; Recombinant Proteins; Thermodynamics

2008
Extracellular Nampt promotes macrophage survival via a nonenzymatic interleukin-6/STAT3 signaling mechanism.
    The Journal of biological chemistry, 2008, Dec-12, Volume: 283, Issue:50

    Topics: Acrylamides; Animals; Apoptosis; Cell Survival; Cytokines; Endoplasmic Reticulum; Gene Expression Regulation; Interleukin-6; Macrophages; Male; Mice; Mice, Inbred C57BL; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Piperidines; Signal Transduction; STAT3 Transcription Factor

2008
Detection and pharmacological modulation of nicotinamide mononucleotide (NMN) in vitro and in vivo.
    Biochemical pharmacology, 2009, May-15, Volume: 77, Issue:10

    Topics: Acetophenones; Acrylamides; Animals; Cell Survival; Chromatography, High Pressure Liquid; Cytokines; Enzyme Inhibitors; Formates; HeLa Cells; Humans; Male; Mice; NAD; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Organ Specificity; Piperidines; U937 Cells

2009
NAMPT/PBEF1 enzymatic activity is indispensable for myeloma cell growth and osteoclast activity.
    Experimental hematology, 2013, Volume: 41, Issue:6

    Topics: Acrylamides; Animals; Bone and Bones; Cell Differentiation; Coculture Techniques; Cytokines; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Mice; Mice, SCID; Multiple Myeloma; NAD; Neoplasm Proteins; NF-kappa B; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Osteoclasts; Osteolysis; Piperidines; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Rabbits; Sirtuin 1; Tumor Cells, Cultured; Up-Regulation

2013
CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cells.
    The Journal of biological chemistry, 2013, Sep-06, Volume: 288, Issue:36

    Topics: 5'-Nucleotidase; Acrylamides; ADP-ribosyl Cyclase 1; Cell Death; Cell Line, Tumor; Cytokines; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Silencing; GPI-Linked Proteins; Humans; Membrane Glycoproteins; NAD; Neoplasm Proteins; Neoplasms; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Piperidines

2013
NAMPT inhibitor and metabolite protect mouse brain from cryoinjury through distinct mechanisms.
    Neuroscience, 2015, Apr-16, Volume: 291

    Topics: Acrylamides; Acute Disease; Animals; Astrocytes; Brain; Brain Injuries; Calcium-Binding Proteins; Cell Count; Chronic Disease; Cold Temperature; Cytokines; Disease Models, Animal; Macrophages; Male; Mice, Inbred BALB C; Microfilament Proteins; Microglia; NAD; Neurons; Neuroprotective Agents; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Piperidines

2015
FK866 compromises mitochondrial metabolism and adaptive stress responses in cultured cardiomyocytes.
    Biochemical pharmacology, 2015, Nov-01, Volume: 98, Issue:1

    Topics: Acrylamides; Animals; Cells, Cultured; Cytokines; Gene Expression Regulation; Hydrogen Peroxide; Insulin; Mitochondria; Myocytes, Cardiac; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Norepinephrine; Piperidines; Rats; Stress, Physiological

2015
Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model.
    Oncotarget, 2016, Jan-19, Volume: 7, Issue:3

    Topics: 5'-Nucleotidase; Acrylamides; Adenosine Triphosphate; Animals; Cell Line, Tumor; Cytokines; Female; GPI-Linked Proteins; Humans; Mice; Mice, Nude; NAD; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Ovarian Neoplasms; Piperidines; Pyridinium Compounds; RNA Interference; RNA, Small Interfering

2016
Wallerian Degeneration Is Executed by an NMN-SARM1-Dependent Late Ca(2+) Influx but Only Modestly Influenced by Mitochondria.
    Cell reports, 2015, Dec-22, Volume: 13, Issue:11

    Topics: Acrylamides; Amidohydrolases; Animals; Armadillo Domain Proteins; Axons; Calcium; Cytoskeletal Proteins; Ions; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Nicotinamide Mononucleotide; Nicotinamide-Nucleotide Adenylyltransferase; Piperidines; Wallerian Degeneration

2015
NAMPT protects against 6-hydroxydopamine-induced neurotoxicity in PC12 cells through modulating SIRT1 activity.
    Molecular medicine reports, 2016, Volume: 13, Issue:5

    Topics: Acrylamides; Animals; Cell Survival; Cytokines; L-Lactate Dehydrogenase; Malondialdehyde; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Oxidopamine; Parkinson Disease, Secondary; PC12 Cells; Piperidines; Rats; Sirtuin 1

2016
Inhibition of NAMPT aggravates high fat diet-induced hepatic steatosis in mice through regulating Sirt1/AMPKα/SREBP1 signaling pathway.
    Lipids in health and disease, 2017, Apr-27, Volume: 16, Issue:1

    Topics: Acrylamides; AMP-Activated Protein Kinases; Animals; Carbazoles; Cell Line; Cytokines; Diet, High-Fat; Enzyme Inhibitors; Gene Expression Regulation; Hep G2 Cells; Hepatocytes; Humans; Liver; Male; Mice; Mice, Inbred C57BL; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Non-alcoholic Fatty Liver Disease; Oleic Acid; Piperidines; Resveratrol; Signal Transduction; Sirtuin 1; Sterol Regulatory Element Binding Protein 1; Stilbenes

2017
Oleate ameliorates palmitate-induced reduction of NAMPT activity and NAD levels in primary human hepatocytes and hepatocarcinoma cells.
    Lipids in health and disease, 2017, Oct-03, Volume: 16, Issue:1

    Topics: Acrylamides; Apoptosis; Cell Survival; Cytokines; Enzyme Inhibitors; Gene Expression; Hep G2 Cells; Hepatocytes; Humans; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Oleic Acid; Palmitic Acid; Piperidines; Primary Cell Culture; RNA, Messenger

2017
Loss of NAMPT in aging retinal pigment epithelium reduces NAD
    Aging, 2018, Jun-12, Volume: 10, Issue:6

    Topics: Acrylamides; Aging; Animals; Cells, Cultured; Cytokines; Epithelial Cells; Gene Expression Regulation; Humans; Male; Mice; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Piperidines; Retinal Pigment Epithelium; Reverse Transcriptase Polymerase Chain Reaction

2018
Pharmacological bypass of NAD
    Proceedings of the National Academy of Sciences of the United States of America, 2018, 10-16, Volume: 115, Issue:42

    Topics: Acrylamides; Animals; Antineoplastic Agents, Phytogenic; Drug Combinations; Francisella tularensis; Ganglia, Spinal; NAD; Nerve Degeneration; Neurons; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Piperidines; Pyridinium Compounds; Vincristine

2018