nickel has been researched along with dinitrochlorobenzene in 31 studies
*Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds. [MeSH]
*Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (12.90) | 18.7374 |
| 1990's | 10 (32.26) | 18.2507 |
| 2000's | 13 (41.94) | 29.6817 |
| 2010's | 4 (12.90) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dive, D; Espigares, M; Odberg-Ferragut, C | 1 |
| Diezel, W; Greiner, J | 1 |
| Gollhausen, R; Kligman, A | 1 |
| Lee, CS; Lewis, RM; Picut, CA | 1 |
| Carr, MM; Gawkrodger, DJ; Guy, K; Hunter, JA; McVittie, E | 1 |
| Hunter, JA | 1 |
| Coban, T; Eke, BC; Iscan, M | 3 |
| Ikeda, Y; Kashima, R; Okada, J | 1 |
| Emahazion, T; Mannervik, B; Widersten, M; Yilmaz, S | 1 |
| Prinsen, MK; Romijn, T; Snoeij, NJ | 1 |
| Aiba, S; Tagami, H | 1 |
| Aiba, S; Manome, H; Singh, S; Tagami, H | 1 |
| Kovac, R; Tuschl, H; Weber, E | 1 |
| Aiba, S; Manome, H; Mizuashi, M; Mollah, ZU; Nakagawa, S; Ohtani, T; Tagami, H; Yoshino, Y | 1 |
| Boislève, F; Kerdine-Römer, S; Pallardy, M; Rougier-Larzat, N | 1 |
| Hirota, M; Moro, O | 1 |
| Friedmann, PS | 1 |
| Ito, Y; Miyazawa, M; Sakaguchi, H; Suzuki, H; Yoshida, Y | 1 |
| Ade, N; Antonios, D; Boisleve, F; Kerdine-Romer, S; Pallardy, M; Rousset, F | 1 |
| Ban, M; Goutet, M; Pépin, E | 1 |
| Ito, Y; Kosaka, N; Miyazawa, M; Nishiyama, N; Nukada, Y; Sakaguchi, H; Suzuki, H | 1 |
| Courtellemont, P; Haftek, M; Le Varlet, B; Migdal, C; Serres, M; Tailhardat, M; Trompezinski, S | 1 |
| Ito, Y; Kosaka, N; Miyazawa, M; Nishiyama, N; Nukada, Y; Sakaguchi, H | 1 |
| Hua, WG; Jin, XP; Lin, HF; Lv, L; Shen, GZ; Tian, F; Xia, ZL; Zhang, YB | 1 |
| Aiba, S; Hagino, S; Hirota, M; Itagaki, H; Kagatani, S; Sasaki, Y; Suzuki, M | 1 |
| Barták, P; Mardešičová, L; Schramlová, J | 1 |
| Cao, YP; Chen, ZY; Li, LJ; Liu, WD; Ma, PC; Tao, Y; Zhang, ML; Zhou, WQ | 1 |
| Aiba, S; Ito, Y; Kimura, Y; Onami, K; Yamasaki, K; Yamauchi, T | 1 |
| Dai, Y; Jia, Q; Li, X; Zhang, J; Zhang, Y; Zhao, X | 1 |
1 trial(s) available for nickel and dinitrochlorobenzene
| Article | Year |
|---|---|
Keratinocyte expression of MHC class II antigens in allergic sensitization and challenge reactions and in irritant contact dermatitis.
Topics: Anthralin; Dermatitis, Contact; Dinitrochlorobenzene; Female; Histocompatibility Antigens Class II; Humans; Immunoenzyme Techniques; Inflammation; Irritants; Male; Middle Aged; Nickel; Skin | 1987 |
30 other study(ies) available for nickel and dinitrochlorobenzene
| Article | Year |
|---|---|
Stress protein synthesis, a potential toxicity marker in Escherichia coli.
Topics: Bacterial Proteins; Cadmium; Dinitrochlorobenzene; Dose-Response Relationship, Drug; Escherichia coli; Heat-Shock Proteins; Leucine; Molecular Weight; Nickel; Potassium Dichromate; Radioisotope Dilution Technique; Thiram; Tritium | 1991 |
[Inflammation-inhibiting effect of magnesium ions in contact eczema reactions].
Topics: Adolescent; Adult; Animals; Dermatitis, Contact; Dinitrochlorobenzene; Female; Humans; Ions; Magnesium Chloride; Male; Mice; Mice, Inbred BALB C; Nickel; Sodium Chloride | 1990 |
The 'angry back': a new concept or old confusion?
Topics: 1-Propanol; Back; Benzalkonium Compounds; Dermatitis, Contact; Dinitrochlorobenzene; Eugenol; Female; Humans; Irritants; Male; Nickel; Patch Tests; Plants, Toxic; Propanols; Skin; Sodium Dodecyl Sulfate; Toxicodendron | 1986 |
Ultrastructural and phenotypic changes in Langerhans cells induced in vitro by contact allergens.
Topics: Allergens; Animals; Cells, Cultured; Dinitrochlorobenzene; Dose-Response Relationship, Immunologic; Drug Hypersensitivity; Histocompatibility Antigens Class II; Hypersensitivity, Delayed; In Vitro Techniques; Langerhans Cells; Lead; Male; Mice; Mice, Inbred BALB C; Microscopy, Electron; Nickel; Nitrates | 1987 |
Langerhans cell damage does occur in contact allergic reactions.
Topics: Dermatitis, Contact; Dinitrochlorobenzene; Humans; Langerhans Cells; Nickel | 1986 |
Differential responses of hepatic monooxygenases and glutathione S-transferases of mice to a combination of cadmium and nickel.
Topics: Aniline Hydroxylase; Animals; Cadmium; Cytochrome P-450 Enzyme System; Cytochromes b5; Dinitrochlorobenzene; Drug Synergism; Epoxy Compounds; Ethacrynic Acid; Ethylmorphine-N-Demethylase; Glutathione; Glutathione Transferase; Liver; Male; Mice; Mixed Function Oxygenases; Nickel; Nitrobenzenes; Nitrophenols; Protease Inhibitors; Substrate Specificity | 1995 |
Differential combined effect of cadmium and nickel on hepatic and renal glutathione S-transferases of the guinea pig.
Topics: Animals; Benzoates; Benzoic Acid; Cadmium; Dinitrochlorobenzene; Ethacrynic Acid; Glutathione Transferase; Guinea Pigs; Kidney; Liver; Male; Nickel; Nitrobenzenes; Nitrophenols; Organophosphorus Compounds; Substrate Specificity | 1994 |
Lymph node cell proliferation assay in guinea pigs for the assessment of sensitizing potentials of chemical compounds.
Topics: Acrolein; Animals; Benzocaine; Dinitrochlorobenzene; Female; Formaldehyde; Guinea Pigs; Intradermal Tests; Lymph Nodes; Lymphocyte Activation; Neomycin; Nickel; Patch Tests; Perfume; Phenylenediamines; Sodium Dodecyl Sulfate | 1994 |
Combined effects of cadmium and nickel on hepatic glutathione S-transferases in rats.
Topics: Animals; Cadmium; Dinitrochlorobenzene; Drug Interactions; Ethacrynic Acid; Glutathione Transferase; Liver; Male; Nickel; Nitrobenzenes; Rats | 1993 |
Generation of a Ni(II) binding site by introduction of a histidine cluster in the structure of human glutathione transferase A1-1.
Topics: Base Sequence; Binding Sites; Chromatography, Affinity; Dinitrochlorobenzene; Glutathione Transferase; Histidine; Humans; Isoenzymes; Metalloproteins; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nickel; Recombinant Proteins | 1995 |
Skin sensitization testing: the relevance of rechallenge and pretreatment with sodium lauryl sulfate in the guinea pig maximization test.
Topics: Animals; Benzocaine; Dinitrochlorobenzene; Female; Guinea Pigs; Irritants; Male; Nickel; Skin; Sodium Dodecyl Sulfate; Sulfathiazole; Sulfathiazoles | 1997 |
Dendritic cells play a crucial role in innate immunity to simple chemicals.
Topics: Antigens, CD; Apoptosis; B7-2 Antigen; Cell Separation; Cells, Cultured; Dendritic Cells; Dinitrochlorobenzene; Humans; Immunity, Innate; Interleukin-1; Membrane Glycoproteins; Monocytes; Nickel; Tumor Necrosis Factor-alpha | 1999 |
The effects of dexamethasone, cyclosporine, and vitamin D(3) on the activation of dendritic cells stimulated by haptens.
Topics: Antigens, CD; B7-2 Antigen; Cholecalciferol; Cyclosporine; Dendritic Cells; Dexamethasone; Dinitrochlorobenzene; Haptens; HLA-DR Antigens; Humans; Immunosuppressive Agents; Membrane Glycoproteins; Nickel; Tumor Necrosis Factor-alpha | 1999 |
The expression of surface markers on dendritic cells as indicators for the sensitizing potential of chemicals.
Topics: Acrolein; Allergens; Antigens, CD; Antigens, Surface; B7-2 Antigen; Cells, Cultured; Dendritic Cells; Dermatitis, Allergic Contact; Dimethyl Sulfoxide; Dinitrochlorobenzene; Enzyme-Linked Immunosorbent Assay; Eugenol; Flow Cytometry; HLA-DR Antigens; Humans; Intercellular Adhesion Molecule-1; Interleukin-1; Interleukin-6; Membrane Glycoproteins; Nickel; RNA, Messenger; Sodium Dodecyl Sulfate; Trinitrobenzenesulfonic Acid; Up-Regulation | 2000 |
p38 Mitogen-activated protein kinase and extracellular signal-regulated kinases play distinct roles in the activation of dendritic cells by two representative haptens, NiCl2 and 2,4-dinitrochlorobenzene.
Topics: Antigens, CD; B7-2 Antigen; Cytokines; Dendritic Cells; Dinitrochlorobenzene; Enzyme Inhibitors; Flavonoids; Humans; I-kappa B Proteins; Imidazoles; Membrane Glycoproteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Monocytes; NF-kappa B; Nickel; p38 Mitogen-Activated Protein Kinases; Phenotype; Phosphorylation; Pyridines; RNA, Messenger | 2003 |
Nickel and DNCB induce CCR7 expression on human dendritic cells through different signalling pathways: role of TNF-alpha and MAPK.
Topics: Antigens, CD34; Antineoplastic Agents; Chemokine CCL19; Chemokines, CC; Dendritic Cells; Dinitrochlorobenzene; Down-Regulation; Female; Fetal Blood; Haptens; Humans; Interleukin-1; Irritants; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Nickel; p38 Mitogen-Activated Protein Kinases; Phenotype; Receptors, CCR7; Receptors, Chemokine; RNA, Messenger; Tumor Necrosis Factor-alpha | 2004 |
MIP-1beta, a novel biomarker for in vitro sensitization test using human monocytic cell line.
Topics: B7-2 Antigen; Biomarkers; Cathepsin B; Cell Line; Chemokine CCL4; Chemokines, CC; Dinitrochlorobenzene; Heme Oxygenase-1; Humans; Interleukin-1; Macrophage Inflammatory Proteins; Monocytes; Nickel; Oligonucleotide Array Sequence Analysis; Phenylenediamines; Skin | 2006 |
Contact sensitisation and allergic contact dermatitis: immunobiological mechanisms.
Topics: Dermatitis, Allergic Contact; Dinitrochlorobenzene; Dose-Response Relationship, Immunologic; Humans; Irritants; Langerhans Cells; Nickel; Patch Tests | 2006 |
Phenotypic alterations and cytokine production in THP-1 cells in response to allergens.
Topics: Allergens; Antigens, CD; Biomarkers; CD40 Antigens; CD83 Antigen; Cell Line, Tumor; Cytokines; Dinitrochlorobenzene; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Immunoglobulins; Irritants; Langerhans Cells; Membrane Glycoproteins; Monocytes; Nickel; Phenotype; Sodium Dodecyl Sulfate | 2007 |
NF-kappaB plays a major role in the maturation of human dendritic cells induced by NiSO(4) but not by DNCB.
Topics: Antigens, CD; Antigens, CD34; B7-2 Antigen; CD83 Antigen; Cytokines; Dendritic Cells; Dinitrochlorobenzene; HLA-DR Antigens; Humans; I-kappa B Kinase; Immunoglobulins; Membrane Glycoproteins; NF-kappa B; Nickel; p38 Mitogen-Activated Protein Kinases; Tumor Necrosis Factor-alpha | 2007 |
Murine bone marrow-derived dendritic cells as a potential in vitro model for predictive identification of chemical sensitizers.
Topics: 4-Aminobenzoic Acid; Acrolein; Allergens; Animals; Antigens, Surface; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Dendritic Cells; Dinitrochlorobenzene; Dinitrofluorobenzene; Irritants; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Nickel; Phenylenediamines; Sodium Dodecyl Sulfate; Toxicity Tests | 2007 |
Role of MAPK signaling pathway in the activation of dendritic type cell line, THP-1, induced by DNCB and NiSO4.
Topics: Allergens; Antigens, CD; Cell Line; Dendritic Cells; Dinitrochlorobenzene; Flow Cytometry; Haptens; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Nickel; Phenotype; Phosphorylation; Tumor Necrosis Factor-alpha | 2008 |
Characterization of early events involved in human dendritic cell maturation induced by sensitizers: cross talk between MAPK signalling pathways.
Topics: Cells, Cultured; Cytokines; Dendritic Cells; Dinitrochlorobenzene; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Humans; MAP Kinase Signaling System; Nickel; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Thimerosal | 2008 |
Production of IL-8 in THP-1 cells following contact allergen stimulation via mitogen-activated protein kinase activation or tumor necrosis factor-alpha production.
Topics: Allergens; Cell Line; Dinitrochlorobenzene; Humans; Interleukin-8; Mitogen-Activated Protein Kinases; Nickel; Tumor Necrosis Factor-alpha | 2008 |
[In vitro evaluation of cutaneous allergic reaction induced by chemicals using dendritic cells].
Topics: Animals; B7-2 Antigen; Cells, Cultured; Dendritic Cells; Dinitrochlorobenzene; Interleukin-12; Interleukin-1beta; Interleukin-6; Mice; Mice, Inbred C57BL; Nickel; Sodium Dodecyl Sulfate | 2008 |
Modification of cell-surface thiols elicits activation of human monocytic cell line THP-1: possible involvement in effect of haptens 2,4-dinitrochlorobenzene and nickel sulfate.
Topics: Animals; B7-2 Antigen; Cattle; Cell Line, Tumor; Cell Membrane; Chemokine CCL4; Dinitrochlorobenzene; Endocytosis; Enzyme Inhibitors; Flow Cytometry; Haptens; Humans; Imidazoles; Irritants; Monocytes; Nickel; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Serum Albumin, Bovine; Sulfhydryl Compounds | 2009 |
Reactivity of Langerhans cells after application of different chemicals--an ultrastructural analysis.
Topics: Acetone; Dinitrochlorobenzene; Ethanol; Humans; Iodine Compounds; Langerhans Cells; Nickel; Skin; Ultrasonography | 2010 |
Evaluation of the skin sensitization potential of chemicals in THP-1/keratinocyte co-cultures.
Topics: Animal Testing Alternatives; B7-2 Antigen; Benzalkonium Compounds; Cell Line, Tumor; Cell Survival; Coculture Techniques; Dermatitis, Allergic Contact; Dinitrochlorobenzene; Eugenol; Formaldehyde; Haptens; Humans; Intercellular Adhesion Molecule-1; Keratinocytes; Lactic Acid; Monocytes; Nickel; Phenylenediamines; Sensitivity and Specificity; Skin Tests; Sodium Dodecyl Sulfate | 2012 |
Nonmetal haptens induce ATP release from keratinocytes through opening of pannexin hemichannels by reactive oxygen species.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Benzopyrans; Cell Death; Cells, Cultured; Connexins; Cystine; Dermatitis, Contact; Dinitrochlorobenzene; Disease Models, Animal; Female; Haptens; Humans; Irritants; Keratinocytes; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Nickel; Protein Structure, Quaternary; Protein Structure, Tertiary; Pyrimidinones; Reactive Oxygen Species; RNA, Small Interfering | 2014 |
[Use of THP-1 for allergens identification method validation].
Topics: Allergens; Cytokines; Dinitrochlorobenzene; Humans; Interleukin-1beta; Interleukin-6; Interleukin-8; Monocytes; Nickel; Sodium Dodecyl Sulfate; Tumor Necrosis Factor-alpha | 2014 |