Compounds > nicardipine

nicardipine and tacrolimus

nicardipine has been researched along with tacrolimus in 14 studies

Research

Studies (14)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (7.14)	18.2507
2000's	4 (28.57)	29.6817
2010's	8 (57.14)	24.3611
2020's	1 (7.14)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Chen, X; Lin, X; Skolnik, S; Wang, J	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF	1
Brandis, M; Epting, T; Fischer-Riepe, P; Gordjani, N; Greger, RF; Leipziger, J; Nitschke, R	1
Fukuchi, T; Igarashi, H; Kamiya, T; Katayama, Y; Katsura, K	1
Buckmaster, PS; Ingram, EA; Toyoda, I; Wen, X	1
Carle, AC; Goebel, J; Hooper, DK; Schuchter, J	1
Fukuda, T; Gardiner, R; Goebel, J; Hooper, DK; Kirby, CL; Logan, B; Roy-Chaudhury, A; Vinks, AA	1
Carpenter, TC; Clark, N; Hurst, AL; Reiter, PD; Sundaram, SS	1
Gaies, E; Klouz, A; Lakhal, M; Salouage, I; Sassi, MB; Trabelsi, S	1

Reviews

2 review(s) available for nicardipine and tacrolimus

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators. European journal of medicinal chemistry, 2022, Jul-05, Volume: 237 Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells	2022

Other Studies

12 other study(ies) available for nicardipine and tacrolimus

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2 Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Cyclosporin-A-induced effects on the free Ca2+ concentration in LLC-PK1-cells and their mechanisms. Pflugers Archiv : European journal of physiology, 2000, Volume: 439, Issue:5 Topics: Adenosine Triphosphate; Animals; Arginine Vasopressin; Biological Transport; Calcineurin Inhibitors; Calcium; Cyclosporine; Estrenes; Fluorescent Dyes; Fura-2; Immunosuppressive Agents; Inositol 1,4,5-Trisphosphate; Kidney Tubules, Proximal; LLC-PK1 Cells; Nicardipine; Phosphodiesterase Inhibitors; Pyrrolidinones; Renal Agents; Signal Transduction; Swine; Tacrolimus; Type C Phospholipases; Vasodilator Agents	2000
[Studies on brain pyruvate dehydrogenase (PDH) activity and energy metabolites during ischemia and reperfusion]. Rinsho shinkeigaku = Clinical neurology, 1999, Volume: 39, Issue:12 Topics: Animals; Brain; Brain Ischemia; Calcium Channel Blockers; Energy Metabolism; Gerbillinae; Immunosuppressive Agents; Nicardipine; Pyruvate Dehydrogenase Complex; Rats; Reperfusion; Tacrolimus; Time Factors	1999
Prolonged infusion of inhibitors of calcineurin or L-type calcium channels does not block mossy fiber sprouting in a model of temporal lobe epilepsy. Epilepsia, 2009, Volume: 50, Issue:1 Topics: Animals; Blotting, Western; Calcineurin Inhibitors; Calcium Channel Blockers; Calcium Channels, L-Type; Cyclosporine; Epilepsy, Temporal Lobe; Immunosuppressive Agents; Male; Mossy Fibers, Hippocampal; Muscarinic Agonists; Nicardipine; Pilocarpine; Rats; Rats, Sprague-Dawley; Tacrolimus; Time Factors	2009
Interaction between tacrolimus and intravenous nicardipine in the treatment of post-kidney transplant hypertension at pediatric hospitals. Pediatric transplantation, 2011, Volume: 15, Issue:1 Topics: Adolescent; Adult; Antihypertensive Agents; Child; Child, Preschool; Databases, Factual; Female; Humans; Hypertension; Immunosuppressive Agents; Kidney Transplantation; Living Donors; Male; Nicardipine; Tacrolimus	2011
Risk of tacrolimus toxicity in CYP3A5 nonexpressors treated with intravenous nicardipine after kidney transplantation. Transplantation, 2012, Apr-27, Volume: 93, Issue:8 Topics: Adolescent; Antihypertensive Agents; Child; Cytochrome P-450 CYP3A; Female; Humans; Hypertension; Immunosuppressive Agents; Kidney Transplantation; Male; Nicardipine; Risk; Tacrolimus; Young Adult	2012
Supra-therapeutic tacrolimus concentrations associated with concomitant nicardipine in pediatric liver transplant recipients. Pediatric transplantation, 2015, Volume: 19, Issue:4 Topics: Alagille Syndrome; Antihypertensive Agents; Biliary Atresia; Carcinoma, Hepatocellular; Child; Child, Preschool; Cholestasis, Intrahepatic; Cytochrome P-450 Enzyme System; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Female; Graft Rejection; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Infant; Liver Neoplasms; Liver Transplantation; Male; Nicardipine; Reoperation; Tacrolimus	2015
Involvement of CYP 3A5 In the Interaction Between Tacrolimus and Nicardipine: A Case Report. Current drug safety, 2015, Volume: 10, Issue:3 Topics: Antihypertensive Agents; Biotransformation; Calcium Channel Blockers; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Drug Monitoring; Drug Substitution; Humans; Hypertension; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Nicardipine; Polypharmacy; Prazosin; Tacrolimus	2015