nicardipine and reserpine

nicardipine has been researched along with reserpine in 23 studies

Research

Studies (23)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (21.74)	18.7374
1990's	2 (8.70)	18.2507
2000's	6 (26.09)	29.6817
2010's	8 (34.78)	24.3611
2020's	2 (8.70)	2.80

Authors

Authors	Studies
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA	1
Casciano, CN; Clement, RP; Johnson, WW; Wang, EJ	1
Globisch, C; Kassack, MU; Klinkhammer, W; Müller, H; Pajeva, IK; Wiese, M	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Müller, H; Pick, A; Wiese, M	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Chen, X; Lin, X; Skolnik, S; Wang, J	1
Sun, H	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Astolfi, A; Barreca, ML; Cecchetti, V; Felicetti, T; Iraci, N; Kaatz, GW; Manfroni, G; Massari, S; Pietrella, D; Sabatini, S; Tabarrini, O	1
Norman, BH	1
Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF	1
Safa, AR; Spearman, T; Van Dyke, K; Ye, ZG	1
Atkinson, J; Benedek, C; Boillat, N; de Rivaz, JC; Fouda, AK; Krause, F; Pitton, MC; Rafizadeh, C; Sautel, M; Trescases, N	1
Mogami, H; Sakamoto, Y; Shimizu, K; Ushio, Y; Yoshida, T	1
Frances, H; Renwart, N; Simon, P	1
Kajiwara, A; Ohizumi, Y; Yasumoto, T	1
Prostran, M; Todorović, Z; Varagić, VM	1
Huguet, F; Piriou, A; Pontcharraud, R; Remblier, C; Vandel, B	1
Bulatova, NR; Darwish, RM	1

Reviews

3 review(s) available for nicardipine and reserpine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Drug Induced Liver Injury (DILI). Mechanisms and Medicinal Chemistry Avoidance/Mitigation Strategies. Journal of medicinal chemistry, 2020, 10-22, Volume: 63, Issue:20 Topics: Animals; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Drug Discovery; Drug Evaluation, Preclinical; Hepatocytes; Humans; Liver; Mitochondria, Liver; Pharmaceutical Preparations; Risk Assessment; Tissue Distribution	2020
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators. European journal of medicinal chemistry, 2022, Jul-05, Volume: 237 Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells	2022

Other Studies

20 other study(ies) available for nicardipine and reserpine

Article	Year
Rational use of in vitro P-glycoprotein assays in drug discovery. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera	2001
Active transport of fluorescent P-glycoprotein substrates: evaluation as markers and interaction with inhibitors. Biochemical and biophysical research communications, 2001, Nov-30, Volume: 289, Issue:2 Topics: 3T3 Cells; Adrenergic Uptake Inhibitors; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Biological Transport, Active; Cell Line; Cell Separation; Cell Survival; Flow Cytometry; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Mice; Protein Binding; Reserpine; Spectrometry, Fluorescence; Substrate Specificity; Time Factors	2001
New functional assay of P-glycoprotein activity using Hoechst 33342. Bioorganic & medicinal chemistry, 2007, Dec-01, Volume: 15, Issue:23 Topics: Adenosine Triphosphatases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Fluoresceins; Humans; Microscopy, Fluorescence; Molecular Structure; Principal Component Analysis; Time Factors	2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structure-activity relationships of new inhibitors of breast cancer resistance protein (ABCG2). Bioorganic & medicinal chemistry, 2008, Sep-01, Volume: 16, Issue:17 Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Humans; Models, Molecular; Molecular Structure; Neoplasm Proteins; Phthalic Acids; Quantitative Structure-Activity Relationship; Quinolines; Reproducibility of Results; Stereoisomerism; Time Factors; Tumor Cells, Cultured	2008
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2 Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity	2011
Capture hydrolysis signals in the microsomal stability assay: molecular mechanisms of the alkyl ester drug and prodrug metabolism. Bioorganic & medicinal chemistry letters, 2012, Jan-15, Volume: 22, Issue:2 Topics: Carboxylic Acids; Cytochrome P-450 Enzyme System; Esters; Humans; Hydrolysis; Microsomes; Models, Molecular; Molecular Structure; Prodrugs; Quantum Theory; Signal Transduction	2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors. Journal of medicinal chemistry, 2017, 02-23, Volume: 60, Issue:4 Topics: Anti-Bacterial Agents; Bacterial Proteins; Drug Repositioning; Humans; Ligands; Models, Molecular; Multidrug Resistance-Associated Proteins; Staphylococcal Infections; Staphylococcus aureus	2017
3H-azidopine photoaffinity labeling of high molecular weight proteins in chloroquine resistant falciparum malaria. Biochemical and biophysical research communications, 1989, Jul-31, Volume: 162, Issue:2 Topics: Affinity Labels; Animals; Azides; Binding, Competitive; Chloroquine; Chlorpromazine; Dihydropyridines; Drug Resistance; Glycoproteins; Molecular Weight; Nicardipine; Photochemistry; Plasmodium falciparum; Proteins; Quinacrine; Reserpine; Trifluoperazine; Verapamil	1989
Alpha-1 and alpha-2 adrenoceptor agonists induce vasoconstriction of the normotensive rat caudal artery in vitro by stimulation of a heterogeneous population of alpha-1 adrenoceptors. Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 338, Issue:5 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Dose-Response Relationship, Drug; Endothelium, Vascular; Male; Nicardipine; Rats; Rats, Inbred Strains; Reserpine; Tail; Vasoconstriction	1988
[Possibility of overcoming of ACNU resistance in an ACNU-resistant subline of C6 rat glioma]. No to shinkei = Brain and nerve, 1986, Volume: 38, Issue:11 Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line; Cells, Cultured; Drug Resistance; Drug Therapy, Combination; Glioma; Male; Nicardipine; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Reserpine; Trifluoperazine; Verapamil	1986
The calcium entry blockers: anti-manic drugs? Progress in neuro-psychopharmacology & biological psychiatry, 1986, Volume: 10, Issue:6 Topics: Amphetamines; Animals; Bipolar Disorder; Calcium Channel Blockers; Diltiazem; Hyperkinesis; Male; Mice; Mice, Inbred Strains; Motor Activity; Nicardipine; Oxolinic Acid; Reserpine; Verapamil	1986
Excitatory effect of the most potent marine toxin, maitotoxin, on the guinea-pig vas deferens. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:1 Topics: Animals; Calcium; Calcium Channel Blockers; Cell Membrane; Chlorpheniramine; Dose-Response Relationship, Drug; Guinea Pigs; Ion Channels; Male; Marine Toxins; Muscle Contraction; Muscle, Smooth; Nicardipine; Nifedipine; Norepinephrine; Oxocins; Phentolamine; Reserpine; Tetrodotoxin; Vas Deferens; Verapamil	1983
Some new evidence on antifatigue action of aminophylline on the isolated hemidiaphragm of the rat. General pharmacology, 1993, Volume: 24, Issue:1 Topics: Adrenergic beta-Antagonists; Aminophylline; Animals; Calcium; Diaphragm; Electric Stimulation; Female; Heparin; In Vitro Techniques; Isometric Contraction; Male; Muscle Contraction; Nicardipine; Nickel; Oxidopamine; Rats; Reserpine; Respiratory Muscles; Sympathetic Nervous System	1993
Origin of extracellular dopamine increase induced by lactic acid striatal perfusion monitored by microdialysis in the awake rat. Neuroreport, 1999, Jun-23, Volume: 10, Issue:9 Topics: Adrenergic Uptake Inhibitors; Animals; Biological Transport; Brain Chemistry; Calcium Channel Blockers; Calcium Channels, L-Type; Corpus Striatum; Dopamine; Extracellular Space; Lactic Acid; Male; Microdialysis; Nicardipine; Piperazines; Rats; Rats, Sprague-Dawley; Reserpine; Sodium Channel Blockers; Sodium Channels; Tetrodotoxin; Tyramine; Wakefulness	1999
Effect of chemosensitizers on minimum inhibitory concentrations of fluconazole in Candida albicans. Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2008, Volume: 17, Issue:2 Topics: Antifungal Agents; Candida albicans; Candidiasis; Cells, Cultured; Chlorpromazine; Drug Resistance, Fungal; Drug Synergism; Drug Therapy, Combination; Fluconazole; Humans; Microbial Sensitivity Tests; Nicardipine; Reserpine	2008