nicardipine and phentolamine

nicardipine has been researched along with phentolamine in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19908 (30.77)18.7374
1990's9 (34.62)18.2507
2000's4 (15.38)29.6817
2010's4 (15.38)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Decker, N; Delgado, A; Leclerc, G; Marciniak, G; Schwartz, J; Velly, J1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Baba, H; Okamura, T; Tanobe, Y; Toda, N1
Fukumitsu, T; Hayashi, H; Tokuno, H; Tomita, T1
Panarace, G; Pedrinelli, R; Salvetti, A; Spessot, M; Taddei, S1
Ogihara, M; Sunaga, K1
Kato, H; Takata, Y1
Pedrinelli, R; Salvetti, A; Taddei, S1
Azuma, H; Karaki, H; Nagase, H; Nakajima, T; Ozaki, H; Urakawa, N1
Bove, AA; Hayes, SN1
Kou, K; Suzuki, H1
Kajiwara, A; Ohizumi, Y; Yasumoto, T1
Carver, LA; Lee, CH; Strosberg, AM1
Daniel, EE; Kwan, CY; Loke, JC; Low, AM1
Dohi, Y; Kojima, M; Sato, K; Sawada, M1
Asanuma, M; Hirata, H; Kondo, Y; Ogawa, N; Tanaka, K1
Hashiyada, H; Kugimiya, T; Miyagawa, N; Shibata, R; Takagi, M; Yamada, T; Yamauchi, H1
Bayguinov, O; Sanders, KM1
Marik, PE; Varon, J1
Chang, LG; Minamiyama, M1
Asada, A; Funao, T; Oda, Y; Tanaka, K1
Ando, T; Ayabe, Y; Fukagawa, H; Hashiguchi, M; Nakamura, K1
Danser, AH; Deinum, J; Geurts, AC; Groothuis, JT; Hopman, MT; Pickkers, P; Rongen, GA; Smits, P1
Hamner, JW; Klassen, SA; Moir, ME; Shoemaker, JK; Tan, CO; Zamir, M1

Reviews

2 review(s) available for nicardipine and phentolamine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The diagnosis and management of hypertensive crises.
    Chest, 2000, Volume: 118, Issue:1

    Topics: Antihypertensive Agents; Aortic Aneurysm; Aortic Dissection; Clonidine; Diazoxide; Enalaprilat; Female; Fenoldopam; Humans; Hypertension; Labetalol; Nicardipine; Nifedipine; Nitroprusside; Phentolamine; Pre-Eclampsia; Pregnancy; Propanolamines; Trimethaphan

2000

Trials

2 trial(s) available for nicardipine and phentolamine

ArticleYear
Biphasic pressor responses to norepinephrine in humans.
    Clinical pharmacology and therapeutics, 1995, Volume: 58, Issue:5

    Topics: Adult; Dose-Response Relationship, Drug; Hemodynamics; Humans; Infusions, Intravenous; Male; Middle Aged; Nicardipine; Norepinephrine; Phentolamine; Prazosin; Pressoreceptors; Sympatholytics; Sympathomimetics; Vasodilator Agents

1995
Sympathetic nonadrenergic transmission contributes to autonomic dysreflexia in spinal cord-injured individuals.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Angiotensin II; Autonomic Dysreflexia; Autonomic Nervous System Diseases; Blood Pressure; Calcium Channel Blockers; Humans; Leg; Male; Middle Aged; Nicardipine; Norepinephrine; Phentolamine; Plethysmography; Receptors, Adrenergic, alpha; Regional Blood Flow; Renin; Spinal Cord Injuries; Vascular Resistance; Young Adult

2010

Other Studies

22 other study(ies) available for nicardipine and phentolamine

ArticleYear
New 1,4-dihydropyridine derivatives combining calcium antagonism and alpha-adrenolytic properties.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:6

    Topics: Animals; Aorta; Calcium Channel Blockers; Calcium Chloride; Cerebral Cortex; Chemical Phenomena; Chemistry; Coronary Vessels; Dihydropyridines; Guinea Pigs; Male; Molecular Structure; Muscle Contraction; Nitrendipine; Prazosin; Rats; Receptors, Adrenergic, alpha; Swine; Vas Deferens; Yohimbine

1989
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index

2014
Mechanism of relaxation induced by K+ and nicotine in dog duodenal longitudinal muscle.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2

    Topics: Adenosine Triphosphate; Animals; Apamin; Atropine; Bradykinin; Cations, Monovalent; Cyclic GMP; Dogs; Duodenum; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nicardipine; Nicotine; Ouabain; Oxyhemoglobins; Phentolamine; Potassium; Tetrodotoxin; Timolol

1992
Increase in calcium channel current by beta-adrenoceptor agonists in single smooth muscle cells isolated from porcine coronary artery.
    British journal of pharmacology, 1990, Volume: 100, Issue:3

    Topics: 4-Aminopyridine; Adrenergic beta-Agonists; Animals; Cadmium; Calcium Channels; Colforsin; Coronary Vessels; In Vitro Techniques; Ion Channels; Isoproterenol; Muscle, Smooth, Vascular; Nicardipine; Norepinephrine; Phentolamine; Swine; Tetraethylammonium Compounds

1990
Calcium entry blockade and agonist-mediated forearm vasoconstriction in hypertensive patients. Difference between nicardipine and verapamil.
    European journal of clinical pharmacology, 1991, Volume: 40, Issue:1

    Topics: Angiotensin II; Forearm; Humans; Hypertension; Lower Body Negative Pressure; Nicardipine; Phentolamine; Propranolol; Vasoconstriction; Verapamil

1991
Effects of calcium channel blockers and hydralazine on plasma glucose levels in streptozotocin-induced diabetic rats in vivo.
    Japanese journal of pharmacology, 1990, Volume: 52, Issue:3

    Topics: Animals; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Catecholamines; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Hexamethonium Compounds; Hydralazine; Male; Nicardipine; Nifedipine; Phentolamine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Starvation

1990
Effects of Ca antagonists on the norepinephrine release and contractile responses of isolated canine saphenous veins to high KCl.
    Japanese journal of pharmacology, 1985, Volume: 37, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Anesthetics, Local; Animals; Calcium Channel Blockers; Diltiazem; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Norepinephrine; Phentolamine; Potassium Chloride; Saphenous Vein; Verapamil

1985
Calcium entry blockade and alpha-adrenergic vascular reactivity in human beings: differences between nicardipine and verapamil.
    Clinical pharmacology and therapeutics, 1989, Volume: 45, Issue:3

    Topics: Adult; Female; Forearm; Histamine; Humans; Hypertension; Male; Middle Aged; Nicardipine; Norepinephrine; Phentolamine; Receptors, Adrenergic, alpha; Regional Blood Flow; Vasoconstriction; Verapamil

1989
Contractile effects of jellyfish toxin extracted from Carybdea rastonii on isolated rabbit aorta.
    Japanese journal of pharmacology, 1986, Volume: 42, Issue:3

    Topics: Animals; Aorta, Thoracic; Chlorpromazine; Cnidarian Venoms; Drug Interactions; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Phentolamine; Rabbits

1986
Ethanol causes epicardial coronary artery vasoconstriction in the intact dog.
    Circulation, 1988, Volume: 78, Issue:1

    Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Vessels; Dogs; Ethanol; Heart Rate; Male; Nicardipine; Oxygen; Phentolamine; Vasoconstriction

1988
Electrical components contributing to the nerve-mediated contractions in the smooth muscles of the rabbit ear artery.
    The Japanese journal of physiology, 1983, Volume: 33, Issue:5

    Topics: Action Potentials; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Female; Guanethidine; In Vitro Techniques; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Phentolamine; Physical Stimulation; Prazosin; Rabbits; Sympathetic Nervous System; Tetrodotoxin; Yohimbine

1983
Excitatory effect of the most potent marine toxin, maitotoxin, on the guinea-pig vas deferens.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:1

    Topics: Animals; Calcium; Calcium Channel Blockers; Cell Membrane; Chlorpheniramine; Dose-Response Relationship, Drug; Guinea Pigs; Ion Channels; Male; Marine Toxins; Muscle Contraction; Muscle, Smooth; Nicardipine; Nifedipine; Norepinephrine; Oxocins; Phentolamine; Reserpine; Tetrodotoxin; Vas Deferens; Verapamil

1983
Antihypertensive drugs: their postural hypotensive effect and their blood pressure lowering activity in conscious normotensive rats.
    Archives internationales de pharmacodynamie et de therapie, 1983, Volume: 261, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Clonidine; Hydrochlorothiazide; Hypotension, Orthostatic; Male; Minoxidil; Nicardipine; Nifedipine; Nitroprusside; Pentolinium Tartrate; Phentolamine; Prazosin; Rats; Rats, Inbred Strains

1983
Sensitivity to protein kinase C inhibitors of nicardipine-insensitive component of high K+ contracture in rat and guinea-pig aorta.
    British journal of pharmacology, 1994, Volume: 112, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aorta, Thoracic; Calcium; Guinea Pigs; Hypertonic Solutions; In Vitro Techniques; Indomethacin; Isoquinolines; Male; Mannitol; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Nicardipine; Phentolamine; Piperazines; Polycyclic Compounds; Potassium Chloride; Protein Kinase C; Rats; Rats, Wistar

1994
M1 receptors in blood pressure-controlled ischemic spontaneously hypertensive rats.
    Stroke, 1995, Volume: 26, Issue:7

    Topics: Animals; Blood Pressure; Cerebrovascular Circulation; Cerebrovascular Disorders; Frontal Lobe; Hippocampus; Hypertension; Ischemic Attack, Transient; Male; Nicardipine; Phentolamine; Protein Binding; Rats; Rats, Inbred SHR; Receptors, Muscarinic; RNA, Messenger

1995
Hemodynamic effects of nicardipine and phentolamine in combination with norepinephrine in a canine low-output-state model.
    Japanese heart journal, 1997, Volume: 38, Issue:5

    Topics: Animals; Cardiac Output, Low; Dogs; Drug Therapy, Combination; Female; Hemodynamics; Male; Myocardial Contraction; Nicardipine; Norepinephrine; Phentolamine; Postoperative Complications; Stimulation, Chemical; Vasodilator Agents

1997
Dissociation between electrical and mechanical responses to nitrergic stimulation in the canine gastric fundus.
    The Journal of physiology, 1998, Jun-01, Volume: 509 ( Pt 2)

    Topics: Animals; Arginine; Atropine; Calcium; Cytosol; Dogs; Electric Stimulation; Female; Gastric Fundus; Guanylate Cyclase; In Vitro Techniques; Male; Membrane Potentials; Muscle Relaxation; Muscle, Smooth; Nicardipine; Nitric Oxide; Nitroprusside; Oxadiazoles; Oxyhemoglobins; Phentolamine; Propranolol; Quaternary Ammonium Compounds; Quinoxalines; Stomach; Synaptic Transmission; Time Factors

1998
Macro- and microcirculatory effects of tetramethylpyrazine and extract of Charthamus tinctorius L. in rabbit mesentery.
    Clinical hemorheology and microcirculation, 2000, Volume: 23, Issue:2-4

    Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Arterioles; Blood Flow Velocity; Blood Pressure; Calcium Channel Blockers; Cardiovascular Agents; Carthamus tinctorius; Drugs, Chinese Herbal; Microcirculation; Microscopy, Video; Neurotransmitter Agents; Nicardipine; Phentolamine; Pyrazines; Rabbits; Splanchnic Circulation

2000
Vasodilation increases the threshold for bupivacaine-induced convulsions in rats.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:3

    Topics: Adrenergic alpha-Antagonists; Anesthetics, Local; Animals; Blood Gas Analysis; Blood Pressure; Brain; Bupivacaine; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Heart Rate; Male; Nicardipine; Phentolamine; Rats; Rats, Sprague-Dawley; Seizures; Vasodilation; Vasodilator Agents

2004
[Anesthetic management of undiagnosed pheochromocytoma: a case report].
    Masui. The Japanese journal of anesthesiology, 2008, Volume: 57, Issue:10

    Topics: Adrenal Gland Neoplasms; Anesthesia; Antihypertensive Agents; Humans; Hypertension; Intraoperative Care; Intraoperative Complications; Male; Middle Aged; Nicardipine; Phentolamine; Pheochromocytoma

2008
Regulation of cerebrovascular compliance compared with forearm vascular compliance in humans: a pharmacological study.
    American journal of physiology. Heart and circulatory physiology, 2023, 01-01, Volume: 324, Issue:1

    Topics: Adrenergic Agents; Adult; Blood Pressure; Cerebrovascular Circulation; Cholinergic Agents; Forearm; Glycopyrrolate; Humans; Nicardipine; Phentolamine; Regional Blood Flow; Retrospective Studies

2023