nicardipine and nimodipine

nicardipine has been researched along with nimodipine in 79 studies

Research

Studies (79)

Timeframe	Studies, this research(%)	All Research%
pre-1990	15 (18.99)	18.7374
1990's	32 (40.51)	18.2507
2000's	11 (13.92)	29.6817
2010's	18 (22.78)	24.3611
2020's	3 (3.80)	2.80

Authors

Authors	Studies
Janis, RA; Triggle, DJ	1
Jacobson, KA; Jiang, JL; Melman, N; Olah, ME; Stiles, GL; van Rhee, AM	1
Topliss, JG; Yoshida, F	1
Bruno-Blanch, L; Gálvez, J; García-Domenech, R	1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P	1
Jolivette, LJ; Ward, KW	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Baraldi, PG; Geppetti, P; Materazzi, S; Preti, D	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Reimão, JQ; Scotti, MT; Tempone, AG	1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP	1
Sun, H	1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B	1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ	1
Bakmiwewa, SM; Ball, HJ; Fatokun, AA; Hunt, NH; Payne, RJ; Tran, A	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF	1
Fitoussi, G; Nègre-Salvayre, A; Salvayre, R; Troly, M	1
Alabadí, JA; Alborch, E; Jover, T; Miranda, FJ; Perales, AJ; Salom, JB; Torregrosa, G	1
Czuczwar, SJ; Gasior, M; Janusz, W; Kleinrok, Z	1
Canevari, L; Dagani, F; Ferrari, R; Tosca, P	1
Abe, H; Katada, K; Nishikibe, M; Orita, M	1
Dong, H; Lu, YQ; Wang, Q; Yang, QQ; Yang, ZC	1
Alabadí, JA; Alborch, E; Alvarez, C; Miranda, FJ; Salom, JB; Torregrosa, G	1
Dedman, JR; Earls, RM; Grotta, JC; Picone, CM; Rhoades, HM; Strong, RA; Yao, LP	1
Adams, HP	1
Argiolas, A; Gessa, GL; Melis, MR; Stancampiano, R	1
Kamei, K; Nishikibe, M; Tsuchida, S	1
Kamei, K; Nagura, J; Nishikibe, M; Suzuki, K	1
Hidaka, H; Matsushima, S; Saitoh, M; Tanaka, T; Watanabe, M	1
Kuwaki, T; Nishimura, T; Ono, T; Satoh, H; Shibayama, F; Yamashita, T	1
Kamei, C; Kurokawa, K; Tasaka, K	1
Baky, S; Nademanee, K; Singh, BN	1
Adams, HP; Biller, J; Godersky, JC	1
Nakajima, A; Nishikibe, M	1
Alps, BJ; Calder, C; Hass, WK; Wilson, AD	1
Kochhar, A; Lyden, PD; Mazzarella, V; Zivin, JA	1
Aihara, H; Kaneko, K; Tsuchida, K; Yamazaki, R	1
Shimizu, Y	1
Kato, H; Takata, Y	1
Andrenyak, DM; Epstein, PM; Fiss, K; Hachisu, R	1
Golfinos, JG; Spetzler, RF; Thompson, BG; Zabramski, JM	1
Hongo, K; Kobayashi, S	1
MacDonald, L; Weir, B	1
Alhayek, G; Fournier, D; Guy, G; Menei, P; Mercier, P; Rizk, T	1
Adachi, I; Gemba, T; Ito, H; Kawakami, M; Masui, M; Matsunaga, K; Nakano, A; Ninomiya, M; Torii, M; Ueda, M	1
Edamatsu, R; Hiramatsu, M; Mori, A; Mori, I; Ohba, S	1
Furuta, S; Hatakeyama, T; Nakamura, K; Sakaki, S	1
Kase, N; Ohnishi, H; Yamura, T	1
al-Ghanem, R; Calvo, MT; Cortés, M; García-Alvarez, F; Gutiérrez, M; Romero, MS	1
Kimura, R; Ohkura, T; Suzuki, M; Uchida, S; Yamada, S; Yamaguchi, M; Yamamoto, M	1
Melon, E; Rimaniol, JM	1
Brudniak, T; Czuczwar, SJ; Gasior, M; Kamiński, R; Kleinrok, Z	1
Titus, F	1
Cohen, C; Perrault, G; Sanger, DJ	1
Garrigos, M; Orlowski, S; Pascaud, C	1
Bisenieks, E; Briede, J; Daija, D; Duburs, G; Makarova, N; Poikans, J; Uldriķis, J	1
Thayer, SA; Usachev, YM	1
Eraković, V; Kriz, J; Simonić, A; Varljen, J; Zupan, G	1
Guan, Z; Saqr, HE; Stokes, BT; Yates, AJ	1
Iwata, S; Mitsuda, M; Nomoto, M	1
Hara, I; Taya, K; Watanabe, Y; Zhang, J	1
Chang, HT; Chen, WC; Huang, JK; Jan, CR; Jiann, BP; Lu, YC; Su, W; Yu, CC	1
Dorsch, NW	1
Abdennour, L; Boch, AL; Bonneville, F; Lejean, L; Puybasset, L	1
An Haack, K; Bennett, MJ; Li, H; Narayan, SB; Tan, L; Warnock, A	1
Komuro, S; Mizuki, Y; Nishimuta, H; Sato, K; Yabuki, M	1
Bekker, A; Blanck, T; Cohen, BH; Galoyan, S; Haile, M; Li, YS; Quartermain, D	1
Ai, J; Cook, DJ; Kan, S; Kasuya, H; Macdonald, RL	1
Cusimano, MD; Etminan, N; Hanggi, D; Hasan, D; Ilodigwe, D; Jaja, B; Lantigua, H; Le Roux, P; Lo, B; Louffat-Olivares, A; Macdonald, RL; Mayer, S; Molyneux, A; Quinn, A; Schenk, T; Schweizer, TA; Singh, J; Spears, J; Todd, M; Torner, J; Vergouwen, MD; Wong, GK	1
Daschil, N; Humpel, C	1
Broderick, JP; Cassarly, CN; Huang, W; Ishfaq, MF; Lobanova, I; Macdonald, RL; Martin, RH; Qureshi, AI; Suarez, JI	1
Ahmadvand, S; Amin-Hanjani, S; Dayyani, M; Grotta, JC; Guyatt, GH; Sadeghirad, B; Wang, Y; Zabihyan, S	1

Reviews

13 review(s) available for nicardipine and nimodipine

Article	Year
New developments in Ca2+ channel antagonists. Journal of medicinal chemistry, 1983, Volume: 26, Issue:6 Topics: Animals; Binding Sites; Calcium; Calcium Channel Blockers; Calmodulin; Electrophysiology; Heart; Humans; Ion Channels; Muscle Relaxation; Muscle, Smooth; Potassium; Sodium; Structure-Activity Relationship; Substrate Specificity	1983
Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents. Journal of medicinal chemistry, 2010, Jul-22, Volume: 53, Issue:14 Topics: Analgesics; Animals; Anti-Inflammatory Agents; Asthma; Humans; Ion Channel Gating; Neurons; Pain; Peripheral Nervous System Diseases; Pulmonary Disease, Chronic Obstructive; Transient Receptor Potential Channels	2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators. European journal of medicinal chemistry, 2022, Jul-05, Volume: 237 Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells	2022
Calcium antagonists in the management of patients with aneurysmal subarachnoid hemorrhage: a review. Angiology, 1990, Volume: 41, Issue:11 Pt 2 Topics: Calcium Channel Blockers; Cerebral Infarction; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Nicardipine; Nimodipine; Subarachnoid Hemorrhage	1990
Second-generation calcium antagonists: search for greater selectivity and versatility. The American journal of cardiology, 1985, Jan-25, Volume: 55, Issue:3 Topics: Animals; Bepridil; Calcium Channel Blockers; Cinnarizine; Electrophysiology; Flunarizine; Heart; Humans; Lidoflazine; Muscle, Smooth, Vascular; Nicardipine; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Pyrrolidines; Structure-Activity Relationship	1985
Calcium antagonists for the treatment of vasospasm following subarachnoid haemorrhage. Neurological research, 1993, Volume: 15, Issue:4 Topics: Animals; Calcium Channel Blockers; Cerebrovascular Circulation; Diltiazem; Humans; Ischemic Attack, Transient; Nicardipine; Nifedipine; Nimodipine; Subarachnoid Hemorrhage	1993
Cerebral vasospasm. Clinical neurosurgery, 1993, Volume: 40 Topics: Aneurysm, Ruptured; Blood Pressure; Blood Volume; Brain Ischemia; Catheterization; Cerebral Infarction; Cerebrovascular Circulation; Humans; Hypertension; Intracranial Aneurysm; Ischemic Attack, Transient; Nicardipine; Nimodipine; Subarachnoid Hemorrhage	1993
[Pharmacological treatment of vasospasm in subarachnoid hemorrhage]. Annales francaises d'anesthesie et de reanimation, 1996, Volume: 15, Issue:3 Topics: Antioxidants; Humans; Ischemic Attack, Transient; Lipid Peroxides; Male; Nicardipine; Nimodipine; Papaverine; Plasminogen Activators; Pregnatrienes; Subarachnoid Hemorrhage; Tissue Plasminogen Activator; Vasodilator Agents	1996
Therapeutic approaches to vasospasm in subarachnoid hemorrhage. Current opinion in critical care, 2002, Volume: 8, Issue:2 Topics: Angioplasty, Balloon; Blood Volume; Calcium Channel Blockers; Fibrinolytic Agents; Fluid Therapy; Hemodilution; Humans; Nicardipine; Nimodipine; Subarachnoid Hemorrhage; Vasospasm, Intracranial	2002
SAHIT Investigators--on the outcome of some subarachnoid hemorrhage clinical trials. Translational stroke research, 2013, Volume: 4, Issue:3 Topics: Antioxidants; Brain Infarction; Calcium Channel Blockers; Critical Care; Dioxanes; Drug Therapy, Combination; Humans; Hypotension; Intracranial Aneurysm; Magnesium Compounds; Neuroprotective Agents; Nicardipine; Nimodipine; Practice Patterns, Physicians'; Pregnatrienes; Pyridines; Pyrimidines; Randomized Controlled Trials as Topic; Salvage Therapy; Sample Size; Subarachnoid Hemorrhage; Sulfonamides; Tetrazoles; Treatment Outcome; Vasodilator Agents; Vasospasm, Intracranial	2013
Lessons Learned from Phase II and Phase III Trials Investigating Therapeutic Agents for Cerebral Ischemia Associated with Aneurysmal Subarachnoid Hemorrhage. Neurocritical care, 2022, Volume: 36, Issue:2 Topics: Brain Ischemia; Cerebral Infarction; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Humans; Multicenter Studies as Topic; Nicardipine; Nimodipine; Subarachnoid Hemorrhage; Treatment Outcome; Vasospasm, Intracranial	2022
Prophylactic Therapies for Morbidity and Mortality After Aneurysmal Subarachnoid Hemorrhage: A Systematic Review and Network Meta-Analysis of Randomized Trials. Stroke, 2022, Volume: 53, Issue:6 Topics: Adult; Brain Ischemia; Cilostazol; Humans; Magnesium; Morbidity; Network Meta-Analysis; Nicardipine; Nimodipine; Randomized Controlled Trials as Topic; Subarachnoid Hemorrhage; Vasospasm, Intracranial	2022

Trials

1 trial(s) available for nicardipine and nimodipine

Article	Year
Calcium antagonists in the management of patients with aneurysmal subarachnoid hemorrhage: a review. Angiology, 1990, Volume: 41, Issue:11 Pt 2 Topics: Calcium Channel Blockers; Cerebral Infarction; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Nicardipine; Nimodipine; Subarachnoid Hemorrhage	1990

Other Studies

66 other study(ies) available for nicardipine and nimodipine

Article	Year
Interaction of 1,4-dihydropyridine and pyridine derivatives with adenosine receptors: selectivity for A3 receptors. Journal of medicinal chemistry, 1996, Jul-19, Volume: 39, Issue:15 Topics: Adenylyl Cyclase Inhibitors; Animals; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Cerebral Cortex; CHO Cells; Cricetinae; Dihydropyridines; Enzyme Inhibitors; Guinea Pigs; Humans; Isradipine; Molecular Structure; Purinergic P1 Receptor Antagonists; Pyridines; Rats; Receptors, Purinergic P1; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship	1996
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship	2003
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability. Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7 Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties	2004
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure. Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7 Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Anti-leishmanial and anti-trypanosomal activities of 1,4-dihydropyridines: In vitro evaluation and structure-activity relationship study. Bioorganic & medicinal chemistry, 2010, Nov-15, Volume: 18, Issue:22 Topics: Animals; Antiprotozoal Agents; Cell Line; Cricetinae; Dihydropyridines; Erythrocytes; Leishmania; Macaca mulatta; Mice; Parasitic Sensitivity Tests; Quantitative Structure-Activity Relationship; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi	2010
Species independence in brain tissue binding using brain homogenates. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7 Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity	2011
Capture hydrolysis signals in the microsomal stability assay: molecular mechanisms of the alkyl ester drug and prodrug metabolism. Bioorganic & medicinal chemistry letters, 2012, Jan-15, Volume: 22, Issue:2 Topics: Carboxylic Acids; Cytochrome P-450 Enzyme System; Esters; Humans; Hydrolysis; Microsomes; Models, Molecular; Molecular Structure; Prodrugs; Quantum Theory; Signal Transduction	2012
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment. Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10 Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers	2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1 Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity	2013
Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2. Bioorganic & medicinal chemistry letters, 2012, Dec-15, Volume: 22, Issue:24 Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; HEK293 Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Substrate Specificity	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump. Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index	2014
Comparative cytoprotective effect of dihydropyridine calcium channel blockers against the toxicity of oxidized low density lipoprotein for cultured lymphoid cells. Biochemical pharmacology, 1992, Dec-15, Volume: 44, Issue:12 Topics: Calcium Channel Blockers; Cell Line; Dihydropyridines; Dose-Response Relationship, Drug; Lipid Peroxidation; Lipoproteins, LDL; Lymphocytes; Nicardipine; Nifedipine; Nimodipine; Nisoldipine	1992
Comparison of the anticonstrictor action of dihydropyridines (nimodipine and nicardipine) and Mg2+ in isolated human cerebral arteries. European journal of pharmacology, 1992, Dec-08, Volume: 229, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Calcium; Cerebral Arteries; Dinoprost; Female; Humans; In Vitro Techniques; Ischemic Attack, Transient; Magnesium; Male; Middle Aged; Nicardipine; Nimodipine; Serotonin; Vasoconstriction	1992
Influence of flunarizine, nicardipine and nimodipine on the anticonvulsant activity of different antiepileptic drugs in mice. Neuropharmacology, 1992, Volume: 31, Issue:11 Topics: Animals; Anticonvulsants; Electroshock; Flunarizine; Male; Mice; Nicardipine; Nimodipine; Postural Balance	1992
Effects of calcium antagonists on glycolysis of rat brain synaptosomes. Biochemical pharmacology, 1992, Jan-22, Volume: 43, Issue:2 Topics: Animals; Brain; Dose-Response Relationship, Drug; Flunarizine; Glycolysis; Hexokinase; Lactates; Male; Nicardipine; Nimodipine; Phosphofructokinase-1; Pyruvate Kinase; Rats; Rats, Inbred Strains; Rotenone; Synaptosomes	1992
Effects of calcium antagonists on the erythrocyte membrane. The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:1 Topics: Animals; Calcium Channel Blockers; Dihydropyridines; Erythrocyte Membrane; Hemolysis; Male; Microscopy, Electron, Scanning; Nicardipine; Nimodipine; Rats; Rats, Inbred Strains	1991
Antagonistic effects of dihydropyridines and verapamil on CaCl2 and 5-HT-evoked contraction in porcine coronary artery. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1991, Volume: 12, Issue:5 Topics: Animals; Calcium Chloride; Coronary Vessels; Dihydropyridines; Felodipine; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Nimodipine; Serotonin Antagonists; Swine; Verapamil	1991
Effects of Ca2+ entry blockers on CaCl2-, KCl- and noradrenaline-induced contractions of goat cerebral arteries. European journal of pharmacology, 1990, Feb-20, Volume: 177, Issue:1-2 Topics: Animals; Calcium Channel Blockers; Calcium Chloride; Cerebral Arteries; Egtazic Acid; Female; Goats; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Nimodipine; Norepinephrine; Potassium Chloride; Verapamil	1990
Neuronal protection correlates with prevention of calcium-calmodulin binding in rats. Stroke, 1990, Volume: 21, Issue:11 Suppl Topics: Animals; Brain Ischemia; Calcium; Calmodulin; Hippocampus; Neurons; Nicardipine; Nimodipine; Pipecolic Acids; Piperidines; Rats	1990
Oxytocin-induced penile erection and yawning: role of calcium and prostaglandins. Pharmacology, biochemistry, and behavior, 1990, Volume: 35, Issue:3 Topics: Animals; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Male; Nicardipine; Nimodipine; Oxytocin; Penile Erection; Prostaglandins; Rats; Rats, Inbred Strains; Second Messenger Systems; Yawning	1990
[Effects of NB-818 on a transient bilateral common carotid arteries occlusion model in Mongolian gerbils]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1989, Volume: 93, Issue:6 Topics: Animals; Arterial Occlusive Diseases; Calcium Channel Blockers; Carotid Artery Diseases; Dihydropyridines; Female; Flunarizine; Gerbillinae; Male; Nicardipine; Nimodipine	1989
Effect of the newly synthetized calcium antagonist isopropyl methyl 2-carbamoyloxymethyl-6-methyl-4-(2,3-dichlorophenyl)-1,4-dihydropyridine-3,5- dicarboxylate on cerebral venous outflow in dogs. Arzneimittel-Forschung, 1989, Volume: 39, Issue:6 Topics: Animals; Blood Gas Analysis; Blood Pressure; Calcium Channel Blockers; Cerebrovascular Circulation; Dihydropyridines; Dogs; Female; Heart Rate; Male; Nicardipine; Nimodipine; Oxygen Consumption; Time Factors; Vascular Resistance	1989
Different sensitivities of Ca2+, calmodulin-dependent cyclic nucleotide phosphodiesterases from rabbit aorta and brain to dihydropyridine calcium channel blockers. Biochemical and biophysical research communications, 1987, Nov-13, Volume: 148, Issue:3 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Aorta; Brain; Calcium Channel Blockers; Cyclic Nucleotide Phosphodiesterases, Type 1; Dihydropyridines; Enzyme Activation; In Vitro Techniques; Kinetics; Nicardipine; Nimodipine; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Rabbits	1987
Nilvadipine attenuates ischemic degradation of gerbil brain cytoskeletal proteins. Stroke, 1989, Volume: 20, Issue:1 Topics: Animals; Brain; Brain Ischemia; Calmodulin-Binding Proteins; Clathrin; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Gerbillinae; Male; Microtubule-Associated Proteins; Nicardipine; Nifedipine; Nimodipine	1989
Hypotensive effects of dihydropyridine derivatives. Arzneimittel-Forschung, 1985, Volume: 35, Issue:9 Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Hydralazine; Nicardipine; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY	1985
Management of aneurysmal subarachnoid hemorrhage. Stroke, 1988, Volume: 19, Issue:10 Topics: Aminocaproic Acid; Humans; Intracranial Aneurysm; Nervous System Diseases; Nicardipine; Nimodipine; Recurrence; Subarachnoid Hemorrhage	1988
Effects of the calcium antagonist NB-818 on cerebral blood flow. Life sciences, 1988, Volume: 43, Issue:21 Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cerebrovascular Circulation; Dihydropyridines; Heart Rate; Macaca mulatta; Male; Nicardipine; Nimodipine; Rabbits; Reference Values; Species Specificity	1988
Comparative protective effects of nicardipine, flunarizine, lidoflazine and nimodipine against ischaemic injury in the hippocampus of the Mongolian gerbil. British journal of pharmacology, 1988, Volume: 93, Issue:4 Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Cerebrovascular Circulation; Female; Flunarizine; Gerbillinae; Hippocampus; Lidoflazine; Male; Nicardipine; Nimodipine	1988
Effects of calcium channel blockers on neurologic outcome after focal ischemia in rabbits. Stroke, 1988, Volume: 19, Issue:8 Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Lidoflazine; Nervous System; Nicardipine; Nimodipine; Rabbits	1988
Effects of the new calcium antagonist 2-nitratopropyl-3-nitratopropyl-2,6-dimethyl-4-(3-nitrophe nyl)- 1,4-dihydropyridine-3,5-dicarboxylate on cerebral circulation in dogs. Arzneimittel-Forschung, 1987, Volume: 37, Issue:11 Topics: Animals; Basilar Artery; Calcium Channel Blockers; Cerebrovascular Circulation; Dihydropyridines; Dinoprost; Dogs; Female; Heart Rate; Hemodynamics; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Nimodipine; Potassium Chloride; Prostaglandins F; Serotonin	1987
[Effect of the calcium entry blockers nicardipine and nimodipine on cerebral function following global anoxia in the rat]. Masui. The Japanese journal of anesthesiology, 1986, Volume: 35, Issue:1 Topics: Animals; Brain; Calcium Channel Blockers; Hypoxia, Brain; Male; Nicardipine; Nicotinic Acids; Nifedipine; Nimodipine; Rats; Rats, Inbred Strains; Resuscitation	1986
Comparative study on acute antihypertensive effects and pharmacokinetics of nisoldipine, nifedipine, nimodipine and nicardipine administered orally to conscious renal hypertensive dogs. Arzneimittel-Forschung, 1986, Volume: 36, Issue:10 Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Heart Rate; Hydralazine; Hypertension, Renal; Kinetics; Male; Nicardipine; Nifedipine; Nimodipine; Nisoldipine; Time Factors	1986
Interaction of calcium antagonists with cyclic AMP phosphodiesterases and calmodulin. Biochemical and biophysical research communications, 1982, Apr-14, Volume: 105, Issue:3 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Brain; Calcium; Calcium Channel Blockers; Calcium-Binding Proteins; Calmodulin; Chickens; Cytosol; Dogs; Humans; Kidney; Kinetics; Lymphocytes; Myocardium; Nicardipine; Nicotinic Acids; Nifedipine; Nimodipine; Pyridines; Rats; Spectrometry, Fluorescence	1982
Are the calcium antagonists really useful in cerebral aneurysmal surgery? A retrospective study. Neurosurgery, 1994, Volume: 35, Issue:3 Topics: Brain Ischemia; Calcium Channel Blockers; Humans; Intracranial Aneurysm; Neuropsychological Tests; Nicardipine; Nimodipine; Randomized Controlled Trials as Topic; Retrospective Studies; Subarachnoid Hemorrhage; Treatment Outcome	1994
Are the calcium antagonists really useful in cerebral aneurysmal surgery? A retrospective study. Neurosurgery, 1994, Volume: 34, Issue:1 Topics: Activities of Daily Living; Adult; Aged; Brain Ischemia; Calcium Channel Blockers; Cerebral Angiography; Female; Follow-Up Studies; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Male; Middle Aged; Neuropsychological Tests; Nicardipine; Nimodipine; Postoperative Complications; Premedication; Preoperative Care; Rehabilitation, Vocational; Retrospective Studies; Subarachnoid Hemorrhage; Survival Rate	1994
Pharmacological studies on a new dihydrothienopyridine calcium antagonist. 4th communication: prophylactic and therapeutic effects of S-(+)-methyl-4,7-dihydro-3-isobutyl-6-methyl-4-(3-nitrophenyl)thieno[2, 3- b]pyridine-5-carboxylate in stroke-prone spont Arzneimittel-Forschung, 1993, Volume: 43, Issue:12 Topics: Animals; Behavior, Animal; Blood Pressure; Body Weight; Brain; Calcium Channel Blockers; Cerebrovascular Disorders; Dihydropyridines; Drinking; Eating; Heart Rate; Hypertension; Life Expectancy; Male; Nicardipine; Nimodipine; Organ Size; Rats; Rats, Inbred SHR; Sodium, Dietary	1993
Metal ions affect neuronal membrane fluidity of rat cerebral cortex. Neurochemical research, 1994, Volume: 19, Issue:3 Topics: Animals; Cations; Cerebral Cortex; Cyclic N-Oxides; Edetic Acid; Egtazic Acid; Electron Spin Resonance Spectroscopy; Flunarizine; Kinetics; Male; Membrane Fluidity; Metals; Neurons; Nicardipine; Nifedipine; Nimodipine; Rats; Rats, Sprague-Dawley; Spin Labels; Synaptosomes	1994
The role of early Ca2+ influx in the pathogenesis of delayed neuronal death after brief forebrain ischemia in gerbils. Brain research, 1993, Jun-11, Volume: 613, Issue:2 Topics: Animals; Autoradiography; Brain; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Cell Death; Choroid Plexus; Dizocilpine Maleate; Female; Gerbillinae; Hippocampus; Ischemic Attack, Transient; Kinetics; Male; Microscopy, Electron; Microtubule-Associated Proteins; Necrosis; Neurons; Nicardipine; Nimodipine; Organ Specificity; Parietal Lobe; Prosencephalon; Pyramidal Cells; Reference Values; Thalamus	1993
[Pharmacological profile of F-0401, a novel dihydropyridine derivative. (2). The vasodilator action of F-0401 in isolated canine arteries]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1993, Volume: 102, Issue:2 Topics: Animals; Arteries; Calcium Channels; Dihydropyridines; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Nimodipine; Potassium Chloride; Vasodilator Agents	1993
The increase in erythrocyte deformability in patients treated with nicardipine or nimodipine. Methods and findings in experimental and clinical pharmacology, 1993, Volume: 15, Issue:2 Topics: Administration, Oral; Adult; Aged; Erythrocyte Deformability; Female; Humans; Male; Middle Aged; Nicardipine; Nimodipine; Vascular Headaches	1993
Alterations in calcium antagonist receptors and calcium content in senescent brain and attenuation by nimodipine and nicardipine. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:2 Topics: Aging; Animals; Binding Sites; Brain; Calcium Channel Blockers; Calcium Channels; Isradipine; Mice; Nicardipine; Nimodipine; omega-Conotoxin GVIA; Peptides	1996
Influence of nicardipine, nimodipine and flunarizine on the anticonvulsant efficacy of antiepileptics against pentylenetetrazol in mice. Journal of neural transmission (Vienna, Austria : 1996), 1996, Volume: 103, Issue:7 Topics: Animals; Anticonvulsants; Calcium Channel Blockers; Clonazepam; Drug Interactions; Ethosuximide; Flunarizine; Male; Mice; Mice, Inbred Strains; Motor Activity; Nicardipine; Nimodipine; Pentylenetetrazole; Random Allocation; Seizures; Valproic Acid	1996
[The treatment of migraine]. Revista de neurologia, 1997, Volume: 25, Issue:138 Topics: Adrenergic beta-Antagonists; Amitriptyline; Calcium Channel Blockers; Dihydroergotamine; Ergotamine; Flunarizine; Humans; Methysergide; Migraine Disorders; Nicardipine; Nimodipine; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Vasoconstrictor Agents	1997
Effects of dihydropyridine Ca2+ channel blockers on the discriminative stimulus and the motor impairing effects of (+/-)-Bay K 8644. European journal of pharmacology, 1997, Oct-08, Volume: 336, Issue:2-3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Discrimination, Psychological; Male; Mice; Motor Activity; Nicardipine; Nifedipine; Nimodipine	1997
Multidrug resistance transporter P-glycoprotein has distinct but interacting binding sites for cytotoxic drugs and reversing agents. The Biochemical journal, 1998, Jul-15, Volume: 333 ( Pt 2) Topics: Adenosine Triphosphatases; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Calcium Channel Blockers; CHO Cells; Cricetinae; Cytotoxins; Dihydropyridines; Drug Resistance, Multiple; Fibroblasts; Nicardipine; Nimodipine; Nitrendipine; Protein Binding; Verapamil; Vinblastine	1998
Effects of some 1,4-dihydropyridine Ca antagonists on the blast transformation of rat spleen lymphocytes. Cell biochemistry and function, 1999, Volume: 17, Issue:2 Topics: Animals; Calcium Channel Blockers; Dihydropyridines; Lymphocyte Activation; Nicardipine; Nifedipine; Nimodipine; Rats; Spleen	1999
Ca2+ influx in resting rat sensory neurones that regulates and is regulated by ryanodine-sensitive Ca2+ stores. The Journal of physiology, 1999, Aug-15, Volume: 519 Pt 1 Topics: Action Potentials; Animals; Animals, Newborn; Biological Transport; Caffeine; Calcium; Calcium Channel Blockers; Cells, Cultured; Ganglia, Spinal; Membrane Potentials; Neurons, Afferent; Nicardipine; Nimodipine; Patch-Clamp Techniques; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Ryanodine; Ryanodine Receptor Calcium Release Channel	1999
The influence of nimodipine, nicardipine and amlodipine on the brain free fatty acid level in rats with penicillin-induced seizures. Progress in neuro-psychopharmacology & biological psychiatry, 1999, Volume: 23, Issue:5 Topics: Amlodipine; Animals; Brain Chemistry; Calcium Channel Blockers; Calcium Channels, L-Type; Fatty Acids, Nonesterified; Male; Nicardipine; Nimodipine; Penicillins; Rats; Rats, Wistar; Seizures	1999
Mechanisms through which PDGF alters intracellular calcium levels in U-1242 MG human glioma cells. Neurochemistry international, 1999, Volume: 35, Issue:6 Topics: Becaplermin; Brain Neoplasms; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Calcium-Transporting ATPases; Elapid Venoms; Endoplasmic Reticulum; Enzyme Inhibitors; Flufenamic Acid; Glioma; Humans; Imidazoles; Ion Transport; Masoprocol; Neoplasm Proteins; Nicardipine; Nimodipine; Nitrendipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; omega-Conotoxins; Peptides; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Ryanodine; Thapsigargin; Tumor Cells, Cultured; Verapamil	1999
Effects of beta-blockers and nicardipine on oxotremorine-induced tremor in common marmosets. Japanese journal of pharmacology, 1999, Volume: 81, Issue:2 Topics: Adrenergic beta-Antagonists; Animals; Calcium Channel Blockers; Callithrix; Flunarizine; Injections, Intraperitoneal; Male; Muscarinic Agonists; Nicardipine; Nimodipine; Oxotremorine; Tremor	1999
Appearance of highly sensitive cells to L-type Ca antagonist in cultured cerebellar granule cells. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 1999, Volume: 19, Issue:4 Topics: Animals; Calcium; Cell Adhesion; Cells, Cultured; Cerebellum; Image Cytometry; Nicardipine; Nifedipine; Nimodipine; Polylysine; Rats; Rats, Wistar	1999
Effect of the organotin compound triethyltin on Ca2+ handling in human prostate cancer cells. Life sciences, 2002, Feb-01, Volume: 70, Issue:11 Topics: Calcium; Calcium-Transporting ATPases; Dose-Response Relationship, Drug; Drug Antagonism; Fura-2; Humans; Male; Nicardipine; Nifedipine; Nimodipine; Prostatic Neoplasms; Thapsigargin; Triethyltin Compounds; Tumor Cells, Cultured	2002
[Endovascular treatment of vasospasm following subarachnoid aneurysmal haemorrhage]. Annales francaises d'anesthesie et de reanimation, 2007, Volume: 26, Issue:11 Topics: Calcium Channel Blockers; Humans; Intracranial Aneurysm; Nicardipine; Nimodipine; Nitroprusside; Papaverine; Phosphodiesterase Inhibitors; Subarachnoid Hemorrhage; Vasospasm, Intracranial	2007
Screening for calcium channel modulators in CLN3 siRNA knock down SH-SY5Y neuroblastoma cells reveals a significant decrease of intracellular calcium levels by selected L-type calcium channel blockers. Biochimica et biophysica acta, 2011, Volume: 1810, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amlodipine; Blotting, Western; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line, Tumor; Child; Drug Evaluation, Preclinical; Flunarizine; Humans; Intracellular Space; Membrane Glycoproteins; Molecular Chaperones; Neuroblastoma; Neuronal Ceroid-Lipofuscinoses; Nicardipine; Nifedipine; Nimodipine; Potassium Chloride; RNA Interference; RNA, Small Interfering	2011
Species differences in intestinal metabolic activities of cytochrome P450 isoforms between cynomolgus monkeys and humans. Drug metabolism and pharmacokinetics, 2011, Volume: 26, Issue:3 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amodiaquine; Animals; Antibodies; Astemizole; Biocatalysis; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Fatty Acids, Unsaturated; Humans; Intestines; Isoenzymes; Lansoprazole; Macaca fascicularis; Microsomes; Microsomes, Liver; Nicardipine; Nimodipine; Paroxetine; Pharmaceutical Preparations; Species Specificity; Terfenadine	2011
Nimodipine-induced hypotension but not nitroglycerin-induced hypotension preserves long- and short-term memory in adult mice. Anesthesia and analgesia, 2012, Volume: 114, Issue:5 Topics: Animals; Avoidance Learning; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Cerebrovascular Circulation; Data Interpretation, Statistical; Hypotension; Memory, Long-Term; Memory, Short-Term; Mice; Nicardipine; Nimodipine; Nitroglycerin; Oxygen Consumption; Recognition, Psychology; Vasodilator Agents	2012
Cisternal sustained release dihydropyridines for subarachnoid hemorrhage. Current neurovascular research, 2012, Volume: 9, Issue:2 Topics: Animals; Delayed-Action Preparations; Dihydropyridines; Disease Models, Animal; Dogs; Female; Macaca fascicularis; Nicardipine; Nimodipine; Placebos; Subarachnoid Hemorrhage; Vasodilator Agents; Vasospasm, Intracranial	2012
Nifedipine and nimodipine protect dopaminergic substantia nigra neurons against axotomy-induced cell death in rat vibrosections via modulating inflammatory responses. Brain research, 2014, Sep-18, Volume: 1581 Topics: Animals; Axotomy; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Death; Cholinergic Neurons; Dopaminergic Neurons; Isradipine; Neuroimmunomodulation; Neuroprotective Agents; Nicardipine; Nifedipine; Nimodipine; Rats, Sprague-Dawley; Substantia Nigra; Tissue Culture Techniques; Ventral Tegmental Area; Verapamil	2014