nicardipine has been researched along with isradipine in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (10.71) | 18.7374 |
| 1990's | 9 (32.14) | 18.2507 |
| 2000's | 8 (28.57) | 29.6817 |
| 2010's | 8 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Reimão, JQ; Scotti, MT; Tempone, AG | 1 |
| Sun, H | 1 |
| Freiwald, S; Jiang, Y; Jones, JP; Kaspera, R; Katayama, J; Lee, CA; Smith, E; Totah, RA; Walker, GS | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Corradi, L; Fogari, R; Malamani, GD; Zoppi, A | 1 |
| Fujimoto, M; Mihara, S | 1 |
| Barradas, J; Gerbeau, C | 1 |
| Ehrhardt, JD; Quennedey, MC; Rouot, B; Schwartz, J; Welsch, M | 1 |
| Al-Mahmood, HA; el-Khatim, MS; Gumaa, KA; Thulesius, O | 1 |
| Dacquet, C; Loirand, G; Mironneau, C; Mironneau, J; Pacaud, P | 1 |
| Brisac, AM; Dubar, M; Huguet, F; Ingrand, P; Piriou, A | 1 |
| Kimura, R; Ohkura, T; Suzuki, M; Uchida, S; Yamada, S; Yamaguchi, M; Yamamoto, M | 1 |
| Groshong, T | 1 |
| Overstreet, DH; Pucilowski, O; Rezvani, AH | 1 |
| Bugiani, O; Florio, T; Forloni, G; Grimaldi, M; Salmona, M; Schettini, G; Scorziello, A; Tagliavini, F | 1 |
| Seibold, JR; Sturgill, MG | 1 |
| Groshong, T; Strauser, LM; Tobias, JD | 1 |
| Achkouty, R; Antakly, MC; Haddad, F; Hayek, G; Khater-Rassi, D; Madi-Jebara, S; Yazigi, A | 1 |
| Sahney, S | 1 |
| Daschil, N; Humpel, C | 1 |
2 review(s) available for nicardipine and isradipine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
A review of calcium channel antagonists in the treatment of pediatric hypertension.
Topics: Amiodarone; Calcium Channel Blockers; Child; Felodipine; Humans; Hypertension; Isradipine; Nicardipine; Nifedipine; Verapamil | 2006 |
2 trial(s) available for nicardipine and isradipine
| Article | Year |
|---|---|
Effects of calcium channel blockers on cardiovascular responses to smoking in normotensive and hypertensive smokers.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Isradipine; Male; Middle Aged; Nicardipine; Smoking | 1992 |
[Comparison of nicardipine and isradipine in hypertension following coronary artery bypass graft].
Topics: Aged; Antihypertensive Agents; Calcium Channel Blockers; Coronary Artery Bypass; Female; Hemodynamics; Humans; Hypertension; Isradipine; Male; Middle Aged; Nicardipine; Postoperative Complications; Prospective Studies; Time Factors | 2002 |
24 other study(ies) available for nicardipine and isradipine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Anti-leishmanial and anti-trypanosomal activities of 1,4-dihydropyridines: In vitro evaluation and structure-activity relationship study.
Topics: Animals; Antiprotozoal Agents; Cell Line; Cricetinae; Dihydropyridines; Erythrocytes; Leishmania; Macaca mulatta; Mice; Parasitic Sensitivity Tests; Quantitative Structure-Activity Relationship; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi | 2010 |
Capture hydrolysis signals in the microsomal stability assay: molecular mechanisms of the alkyl ester drug and prodrug metabolism.
Topics: Carboxylic Acids; Cytochrome P-450 Enzyme System; Esters; Humans; Hydrolysis; Microsomes; Models, Molecular; Molecular Structure; Prodrugs; Quantum Theory; Signal Transduction | 2012 |
Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity.
Topics: Amiodarone; Astemizole; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Danazol; Drug Discovery; Drug Interactions; Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Methylation; Microsomes, Liver; Models, Biological; Molecular Structure; Substrate Specificity; Tandem Mass Spectrometry; Terfenadine | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Effect of S-312, a new calcium channel blocker, on the 1,4-dihydropyridine binding sites in porcine basilar blood vessels and rat aortic smooth muscle cells.
Topics: Animals; Aorta; Basilar Artery; Binding Sites; Calcium; Calcium Channel Blockers; Cells, Cultured; Dihydropyridines; Isradipine; Muscle, Smooth, Vascular; Nicardipine; Nitrendipine; Oxadiazoles; Rats; Swine | 1991 |
A radioreceptor assay for determination of nicardipine in human serum using 3H(+)PN 200-110 as radioligand.
Topics: Animals; Binding, Competitive; Calcium Channels; Humans; In Vitro Techniques; Isradipine; Kinetics; Male; Nicardipine; Nitrendipine; Oxadiazoles; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Reproducibility of Results; Stereoisomerism; Tritium | 1990 |
Improved radioreceptor assay for the determination of plasma levels of dihydropyridine calcium channel blockers in humans.
Topics: Animals; Calcium Channel Blockers; Dihydropyridines; Isradipine; Male; Mass Spectrometry; Nicardipine; Nitrendipine; Pyridines; Radioligand Assay; Rats; Rats, Inbred Strains | 1989 |
The effect of calcium-blockers nicardipine, darodipine, PN-200-110 and nifedipine on insulin release from isolated rat pancreatic islets.
Topics: Animals; Calcium Channel Blockers; Cells, Cultured; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Isradipine; Male; Nicardipine; Nifedipine; Oxadiazoles; Rats; Rats, Inbred Strains | 1986 |
Comparison of binding affinities and calcium current inhibitory effects of a 1,4-dihydropyridine derivative (PN 200-110) in vascular smooth muscle.
Topics: Animals; Binding Sites; Calcium; Electrophysiology; Horses; Isradipine; Kinetics; Muscle, Smooth, Vascular; Nicardipine; Oxadiazoles; Stereoisomerism | 1988 |
Endothelin modulates dihydropyridine receptor decreased binding in hippocampal slices from normotensive and spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Animals; Calcium Channel Agonists; Calcium Channels; Calcium Channels, L-Type; Endothelins; Hippocampus; Hypertension; In Vitro Techniques; Isradipine; Male; Membranes; Muscle Proteins; Nicardipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar | 1993 |
Alterations in calcium antagonist receptors and calcium content in senescent brain and attenuation by nimodipine and nicardipine.
Topics: Aging; Animals; Binding Sites; Brain; Calcium Channel Blockers; Calcium Channels; Isradipine; Mice; Nicardipine; Nimodipine; omega-Conotoxin GVIA; Peptides | 1996 |
Hypertensive crisis in children.
Topics: Antihypertensive Agents; Emergencies; Enalapril; Humans; Hypertension; Isradipine; Labetalol; Nicardipine; Nitroprusside | 1996 |
Role of taste aversion in calcium channel inhibitor-induced suppression of saccharin and alcohol drinking in rats.
Topics: Alcohol Drinking; Animals; Avoidance Learning; Calcium Channel Blockers; Conditioning, Classical; Diltiazem; Dose-Response Relationship, Drug; Drinking; Isradipine; Male; Nicardipine; Rats; Rats, Sprague-Dawley; Saccharin; Taste | 1996 |
Intracellular calcium rise through L-type calcium channels, as molecular mechanism for prion protein fragment 106-126-induced astroglial proliferation.
Topics: Amino Acid Sequence; Animals; Astrocytes; Binding, Competitive; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Division; Cells, Cultured; Cerebral Cortex; DNA; Isradipine; Kinetics; Molecular Sequence Data; Nicardipine; Peptide Fragments; Peptides; Prions; Rats; Thymidine; Time Factors | 1996 |
Rational use of calcium-channel antagonists in Raynaud's phenomenon.
Topics: Amlodipine; Calcium Channel Blockers; Diltiazem; Felodipine; Humans; Isradipine; Nicardipine; Nifedipine; Raynaud Disease | 1998 |
Initial experience with isradipine for the treatment of hypertension in children.
Topics: Administration, Oral; Antihypertensive Agents; Blood Pressure; Body Weight; Calcium Channel Blockers; Capsules; Child; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; Half-Life; Humans; Hypertension; Hypertension, Renal; Infant; Infant, Newborn; Injections, Intravenous; Isradipine; Male; Myocardial Contraction; Nicardipine; Peritoneal Dialysis; Retrospective Studies | 2000 |
Nifedipine and nimodipine protect dopaminergic substantia nigra neurons against axotomy-induced cell death in rat vibrosections via modulating inflammatory responses.
Topics: Animals; Axotomy; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Death; Cholinergic Neurons; Dopaminergic Neurons; Isradipine; Neuroimmunomodulation; Neuroprotective Agents; Nicardipine; Nifedipine; Nimodipine; Rats, Sprague-Dawley; Substantia Nigra; Tissue Culture Techniques; Ventral Tegmental Area; Verapamil | 2014 |