nicardipine and carvedilol

nicardipine has been researched along with carvedilol in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (15.38)18.2507
2000's7 (53.85)29.6817
2010's4 (30.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Casciano, CN; Clement, RP; Johnson, WW; Wang, EJ1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Bakmiwewa, SM; Ball, HJ; Fatokun, AA; Hunt, NH; Payne, RJ; Tran, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cheng, HY; Feuerstein, GZ; Gu, JL; Mckenna, PJ; Ruffolo, RR; Yue, TL1
Fyhrquist, F; Metsärinne, K; Saijonmaa, O1
Hobara, N; Hokama, N; Kameya, H; Ohshiro, S; Sakai, M; Sakanashi, M1
Iida, H; Iwasawa, K; Jo, T; Ma, J; Nagai, R; Nakajima, T; Omata, M1

Reviews

1 review(s) available for nicardipine and carvedilol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

12 other study(ies) available for nicardipine and carvedilol

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Active transport of fluorescent P-glycoprotein substrates: evaluation as markers and interaction with inhibitors.
    Biochemical and biophysical research communications, 2001, Nov-30, Volume: 289, Issue:2

    Topics: 3T3 Cells; Adrenergic Uptake Inhibitors; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Biological Transport, Active; Cell Line; Cell Separation; Cell Survival; Flow Cytometry; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Mice; Protein Binding; Reserpine; Spectrometry, Fluorescence; Substrate Specificity; Time Factors

2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2.
    Bioorganic & medicinal chemistry letters, 2012, Dec-15, Volume: 22, Issue:24

    Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; HEK293 Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Substrate Specificity

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Carvedilol, a new antihypertensive agent, prevents lipid peroxidation and oxidative injury to endothelial cells.
    Hypertension (Dallas, Tex. : 1979), 1993, Volume: 22, Issue:6

    Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Antihypertensive Agents; Carbazoles; Carvedilol; Cattle; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Free Radical Scavengers; Free Radicals; Glutathione; L-Lactate Dehydrogenase; Lipid Peroxidation; Nicardipine; Oxidation-Reduction; Probucol; Propanolamines; Reactive Oxygen Species

1993
Carvedilol and its metabolites suppress endothelin-1 production in human endothelial cell culture.
    Blood pressure, 1997, Volume: 6, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Ascorbic Acid; Calcium Channel Blockers; Carbazoles; Carvedilol; Cells, Cultured; Endothelin-1; Endothelium, Vascular; Humans; Metoprolol; Nicardipine; Prazosin; Probucol; Propanolamines; Propranolol; Umbilical Veins

1997
Influence of nicardipine and nifedipine on plasma carvedilol disposition after oral administration in rats.
    The Journal of pharmacy and pharmacology, 2002, Volume: 54, Issue:6

    Topics: Administration, Oral; Animals; Area Under Curve; Calcium Channel Blockers; Carbazoles; Carvedilol; Chromatography, High Pressure Liquid; Drug Interactions; Male; Nicardipine; Nifedipine; Propanolamines; Rats; Rats, Sprague-Dawley; Time Factors

2002
Inhibitory effects of carvedilol on calcium channels in vascular smooth muscle cells.
    Japanese heart journal, 2003, Volume: 44, Issue:6

    Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Aorta; Calcium; Calcium Channels; Calcium Signaling; Carbazoles; Carvedilol; Cell Division; Endothelin-1; Metoprolol; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Propanolamines; Rats; Vasodilator Agents; Vasopressins

2003