nicardipine has been researched along with captopril in 43 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (20.93) | 18.7374 |
| 1990's | 18 (41.86) | 18.2507 |
| 2000's | 10 (23.26) | 29.6817 |
| 2010's | 6 (13.95) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Jolivette, LJ; Ward, KW | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Bakmiwewa, SM; Ball, HJ; Fatokun, AA; Hunt, NH; Payne, RJ; Tran, A | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Kumagai, H; Matsumura, Y; Ryuzaki, M; Saruta, T; Suzuki, H | 1 |
| Buoninconti, R; Errico, M; Freda, M; Giordano, MP; Granata, Q; Lucentini, ML; Mancia, G; Marsili, P; Pasotti, C; Piccolo, E | 1 |
| Kawasaki, H | 1 |
| Lacourcière, Y; Lévesque, C; Poirier, L; Provencher, P | 1 |
| Celentano, A; De Simone, G; Ferrara, LA; Mancini, M | 1 |
| Bayram, A; Komsuoğlu, B; Komsuoğlu, SS; Sengün, B | 1 |
| Katsumata, H; Nakamoto, H; Ohishi, A; Sakaguchi, H; Saruta, T; Suzuki, H | 1 |
| Boitard, C; Delgado, AG; Gnionsahe, DA; Grünfeld, JP; Hannedouche, TP; Lacour, B | 1 |
| D'Orleans-Juste, P; De Nucci, G; Vane, JR | 1 |
| Scapellato, L; Stornello, M; Valvo, EV | 1 |
| Littler, WA; Smith, SA | 1 |
| Akabane, S; Ito, K; Kawamura, M; Kojima, S; Matsushima, Y | 1 |
| Bartoli, P; Bernardi, D; Ferreri, A; Geri, AB; Ieri, A | 1 |
| Abe, H; Ashida, T; Deguchi, F; Imanishi, M; Kawamura, M; Kawano, Y; Kimura, G; Kojima, S; Yoshida, K; Yoshimi, H | 1 |
| Conrad, KA; Davis, TP; Fagan, TC; Johnson, DG; Mayshar, P | 1 |
| Carver, LA; Lee, CH; Strosberg, AM | 1 |
| Freslon, JL; Giudicelli, JF; Richer, C | 1 |
| Ichikawa, M; Kumagai, H; Kumagai, K; Nishizawa, M; Ryuzaki, M; Saruta, T; Suzuki, H | 1 |
| Boucher, L; Cozic, JA; Gorlier, R; Huin, P; Pettenuzzo-Mollo, M; Provendier, O; Raccah, D; Sicard, J; Vague, P | 1 |
| Asano, M; Inagaki, O; Shibasaki, M; Takenaka, T; Usui, T | 1 |
| Ichikawa, M; Jimbo, M; Kumagai, H; Matsumura, Y; Ryuzaki, M; Saruta, T; Suzuki, H | 1 |
| Kanno, Y; Okada, H; Saruta, T; Suzuki, H; Takenaka, T | 1 |
| Furukawa, S; Hayashi, K; Hirata, H; Masuda, Y; Shikada, K; Shudo, C; Sugita, H; Tamura, T; Tanaka, S; Tomita, K | 1 |
| Asano, M; Inagaki, O; Sudoh, K; Takenaka, T; Tanaka, H | 1 |
| Hiwada, K; Ito, T; Joh, T; Muneta, S; Ochi, T; Sumimoto, T | 1 |
| Benatar, D; Gheorghiade, M; Hall, V; Reddy, S | 1 |
| Hamada, M; Hiwada, K; Honda, T; Matsumoto, Y; Matsuoka, H; Shigematsu, Y | 1 |
| Hanamiya, M; Nakashima, Y; Nomura, M; Serino, R; Ueta, Y; Yamaguchi, KI; Yamamoto, Y; Yamashita, H | 1 |
| Bregonzio, C; Falcón-Neri, A; Ito, T; Saavedra, JM; Terrón, JA; Yamakawa, H | 1 |
| Addad, F; Ben Farhat, M; Chaabani, A; Dridi, Z; Ferjani, H; Gamra, H; Jelliti, M; Khaldoun, BH; Makni, H | 1 |
| Imai, K; Tsunoda, M; Yamagishi, M; Yanagisawa, T | 1 |
| Beutler, JJ; de Gooijer, A; Gaillard, CA; Kroon, AA; van den Born, BJ; van den Meiracker, AH | 1 |
2 review(s) available for nicardipine and captopril
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Antihypertensive agents--the race for third place.
Topics: Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Captopril; Diazoxide; Felodipine; Humans; Hydralazine; Indoramin; Labetalol; Minoxidil; Nicardipine; Nifedipine; Vasodilator Agents; Verapamil | 1985 |
13 trial(s) available for nicardipine and captopril
| Article | Year |
|---|---|
[Efficacy and tolerability of nicardipine retard and captopril in hypertension in the aged. Results of a multicenter study].
Topics: Aged; Aged, 80 and over; Blood Pressure; Captopril; Delayed-Action Preparations; Drug Tolerance; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nicardipine; Time Factors | 1992 |
Ambulatory blood pressure monitoring for the assessment of nicardipine as a third drug in severe essential hypertension.
Topics: Adult; Aged; Ambulatory Care; Blood Pressure Determination; Capsules; Captopril; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Monitoring, Physiologic; Nicardipine | 1992 |
Comparative effects on blood pressure and regional hemodynamics of nicardipine and captopril.
Topics: Adult; Blood Pressure; Captopril; Cardiac Output; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nicardipine; Regional Blood Flow | 1991 |
Treatment of hypertensive urgencies with oral nifedipine, nicardipine, and captopril.
Topics: Administration, Sublingual; Blood Pressure; Captopril; Emergencies; Female; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine; Time Factors | 1991 |
Hemodynamic, renal, and humoral effects of the calcium entry blocker nicardipine and converting enzyme inhibitor captopril in hypertensive type II diabetic patients with nephropathy.
Topics: Adult; Blood Pressure; Captopril; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Combinations; Female; Heart Rate; Hemodynamics; Humans; Kidney; Kidney Function Tests; Male; Nicardipine | 1989 |
Assessment of captopril and nicardipine effects on chronic occlusive arterial disease of the lower extremity using Doppler ultrasound.
Topics: Arterial Occlusive Diseases; Blood Flow Velocity; Captopril; Clinical Trials as Topic; Double-Blind Method; Exercise Test; Humans; Intermittent Claudication; Leg; Male; Middle Aged; Nicardipine; Random Allocation; Ultrasonography | 1988 |
Antihypertensive effects of parenteral nicardipine alone and in combination with captopril.
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Captopril; Drug Therapy, Combination; Heart Rate; Humans; Hypertension; Injections, Intravenous; Middle Aged; Nicardipine | 1987 |
Comparison of the effects of captopril and nicardipine on insulin sensitivity and thrombotic profile in patients with hypertension and android obesity. CaptISM Study Group. Captopril Insulin Sensitivity Multicenter Study Group.
Topics: Adult; Aged; Antigens; Blood Pressure; Captopril; Double-Blind Method; Factor VII; Female; Fibrinogen; Glucose Tolerance Test; Humans; Hypertension; Insulin; Insulin Resistance; Lipids; Male; Middle Aged; Nicardipine; Obesity; Radioimmunoassay; Risk Factors | 1994 |
Calcium channel blockers versus ACE inhibitors as antihypertensives in polycystic kidney disease.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Captopril; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine; Polycystic Kidney Diseases | 1996 |
Both a calcium antagonist and ACE inhibitor reverse hypertrophy in hypertension but a calcium antagonist also depresses contractility.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Captopril; Double-Blind Method; Echocardiography; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Myocardial Contraction; Nicardipine; Ventricular Function, Left | 1997 |
Clinical and neurohormonal effects of nicardipine hydrochloride in patients with severe chronic heart failure receiving angiotensin-converting enzyme inhibitor therapy.
Topics: Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Captopril; Cardiotonic Agents; Digoxin; Disease Progression; Diuretics; Double-Blind Method; Drug Therapy, Combination; Exercise Test; Female; Heart Failure; Humans; Male; Middle Aged; Neurosecretory Systems; Nicardipine; Norepinephrine; Renin; Severity of Illness Index; Stroke Volume; Treatment Outcome | 1998 |
Effect of antihypertensive therapy on aortic distensibility in patients with essential hypertension: comparison with trichlormethiazide, nicardipine and alacepril.
Topics: Age Factors; Antihypertensive Agents; Aorta; Blood Pressure; Captopril; Echocardiography; Elasticity; Female; Humans; Hypertension; Magnetic Resonance Imaging; Male; Middle Aged; Nicardipine; Trichlormethiazide | 1999 |
[A comparison of the effect of oral captopril and nicardipine in hypertensive crisis].
Topics: Administration, Oral; Aged; Antihypertensive Agents; Captopril; Female; Humans; Hypertension; Male; Middle Aged; Nicardipine; Prospective Studies | 2008 |
28 other study(ies) available for nicardipine and captopril
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; HEK293 Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Substrate Specificity | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Differential effects of captopril and nicardipine on baroreflex control of sympathetic nerve activity and heart rate in renal hypertension.
Topics: Angiotensin II; Animals; Arginine; Blood Pressure; Captopril; Female; Heart Rate; Hypertension, Renal; Kidney; Logistic Models; Nicardipine; Pressoreceptors; Rabbits; Reflex; Sympathetic Nervous System | 1992 |
Effects of chronic administration of antihypertensive drugs on vasodilation mediated by calcitonin gene-related peptide-containing vasodilator nerves in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcitonin Gene-Related Peptide; Captopril; Electric Stimulation; In Vitro Techniques; Male; Methoxamine; Nicardipine; Peripheral Nerves; Propranolol; Rats; Rats, Inbred SHR; Splanchnic Circulation; Tetrodotoxin; Vasodilation | 1992 |
Effects of antihypertensive agents on blood pressure and the progress of renal failure in partially nephrectomized spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Kidney; Kidney Failure, Chronic; Nephrectomy; Nicardipine; Rats; Rats, Inbred SHR; Trichlormethiazide | 1990 |
Renal hemodynamics and segmental tubular reabsorption in early type 1 diabetes.
Topics: Adult; Captopril; Diabetes Mellitus, Type 1; Female; Glomerular Filtration Rate; Hemodynamics; Humans; Kidney Tubules; Lithium; Male; Nicardipine; Renal Circulation; Sodium | 1990 |
Endothelin-1 contracts isolated vessels independently of dihydropyridine-sensitive Ca2+ channel activation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channels; Captopril; Dihydropyridines; Dogs; Endothelins; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Peptides; Rabbits | 1989 |
Effects of captopril and nicardipine on renal hyperfiltration and hypertrophy in uninephrectomized diabetic rats.
Topics: Animals; Captopril; Diabetes Mellitus, Experimental; Glomerular Filtration Rate; Hypertrophy; Kidney; Male; Nephrectomy; Nicardipine; Rats; Rats, Inbred Strains | 1988 |
Antihypertensive drugs and sodium restriction. Analysis of their interaction based on pressure-natriuresis relationship.
Topics: Antihypertensive Agents; Blood Pressure; Captopril; Diet, Sodium-Restricted; Female; Humans; Hypertension; Male; Middle Aged; Natriuresis; Nicardipine; Propranolol | 1988 |
Antihypertensive drugs: their postural hypotensive effect and their blood pressure lowering activity in conscious normotensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Clonidine; Hydrochlorothiazide; Hypotension, Orthostatic; Male; Minoxidil; Nicardipine; Nifedipine; Nitroprusside; Pentolinium Tartrate; Phentolamine; Prazosin; Rats; Rats, Inbred Strains | 1983 |
[Antihypertensives and the prevention of development of genetic hypertension in the hypertensive SHR rat].
Topics: Animals; Antihypertensive Agents; Atenolol; Captopril; Cardiomegaly; Dihydralazine; Dose-Response Relationship, Drug; Hydrochlorothiazide; Hypertension; Male; Nicardipine; Nifedipine; Prazosin; Rats; Rats, Inbred Strains; Time Factors; Vasodilator Agents | 1980 |
Different responses of renal blood flow and sympathetic nerve activity to captopril and nicardipine in conscious renal hypertensive rabbits.
Topics: Analysis of Variance; Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Captopril; Disease Models, Animal; Female; Heart Rate; Hypertension, Renal; Kidney; Nicardipine; Norepinephrine; Rabbits; Regional Blood Flow; Renal Circulation; Sympathetic Nervous System; Vascular Resistance; Vasodilation | 1995 |
Pharmacokinetics and cardiovascular effects of YM-21095, a novel renin inhibitor, in dogs and monkeys.
Topics: Aldosterone; Animals; Biological Availability; Captopril; Cardiovascular System; Chromatography, High Pressure Liquid; Dipeptides; Dogs; Female; Heart Rate; Male; Models, Biological; Morpholines; Naphthalenes; Nicardipine; Renin; Saimiri | 1994 |
Central and peripheral vasopressin interact differently with sympathetic nervous system and renin-angiotensin system in renal hypertensive rabbits.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Captopril; Clonidine; Disease Models, Animal; Female; Hypertension, Renovascular; Kidney; Nicardipine; Norepinephrine; Rabbits; Renin-Angiotensin System; Sympathetic Nervous System | 1993 |
Effects of efonidipine, nicardipine and captopril on proteinuria in aged spontaneously hypertensive rats.
Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Calcium Channel Blockers; Captopril; Creatinine; Dihydropyridines; Heart Rate; Hypertension; Kidney; Male; Nicardipine; Nitrophenols; Organophosphorus Compounds; Proteinuria; Rats; Rats, Inbred SHR | 1996 |
Effect of tamsulosin, a novel alpha 1-adrenoceptor antagonist, on urethral pressure profile in anaesthetized dogs.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Dogs; Dose-Response Relationship, Drug; Male; Nicardipine; Prazosin; Pressure; Prostate; Quinazolines; Sulfonamides; Tamsulosin | 1996 |
Increased levels of hypothalamic neuronal nitric oxide synthase and vasopressin in salt-loaded Dahl rat.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Brain Chemistry; Captopril; Gene Expression; In Situ Hybridization; Male; NADPH Dehydrogenase; Neurons; Nicardipine; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Osmolar Concentration; Oxytocin; Paraventricular Hypothalamic Nucleus; Radioimmunoassay; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; RNA, Messenger; Sodium; Sodium Chloride, Dietary; Supraoptic Nucleus; Vasopressins | 2001 |
Protection against ischemia and improvement of cerebral blood flow in genetically hypertensive rats by chronic pretreatment with an angiotensin II AT1 antagonist.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Flow Velocity; Blood Pressure; Brain; Brain Ischemia; Calcium Channel Blockers; Captopril; Cerebrovascular Circulation; Disease Models, Animal; Drug Administration Schedule; Hypertension; Infarction, Middle Cerebral Artery; Male; Nicardipine; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Tetrazoles | 2002 |
Study of the acute cardiovascular effects of several antihypertensive agents with the measurement of plasma catecholamines in mice.
Topics: Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Captopril; Catecholamines; Chromatography, High Pressure Liquid; Heart Rate; Imidazoles; Luminescence; Male; Mice; Mice, Inbred C57BL; Nicardipine; Nitroprusside; Oxalates; Reproducibility of Results; Sensitivity and Specificity; Tetrazoles; Time Factors | 2009 |
Dutch guideline for the management of hypertensive crisis -- 2010 revision.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Captopril; Emergency Treatment; Humans; Hypertension; Hypertensive Retinopathy; Internal Medicine; Labetalol; Netherlands; Nicardipine; Nifedipine; Nitroprusside; Practice Guidelines as Topic | 2011 |