niacinamide and theophylline

niacinamide has been researched along with theophylline in 61 studies

Research

Studies (61)

TimeframeStudies, this research(%)All Research%
pre-199041 (67.21)18.7374
1990's5 (8.20)18.2507
2000's1 (1.64)29.6817
2010's12 (19.67)24.3611
2020's2 (3.28)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Balsamini, C; Bonifazi, P; Duranti, E; Lombardelli, G; Peruzzi, G1
Claycomb, WC1
Davies, MI; Halldórsson, H; Shall, S; Skidmore, CJ1
Butt, NM; Collier, HO; Lovely, JR; Saeed, SA1
Hoshi, Y; Kawai, M; Nasu, S; Shimoyama, M; Shioji, K1
Falk, G; Freeman, M; Marshall, AT; Prenton, E; Shiells, RA; Slack, I1
Andersson, A; Groth, CG; Hellerström, C; Korsgren, O; Petersson, B; Sandler, S; Tollemar, J1
Grahn, H; Grätz, R; Kröger, H1
Cochrane, CG; Hinshaw, DB; Hyslop, PA; Schraufstatter, IU; Sklar, LA; Spragg, RG1
González Cappa, SM; Isola, EL; Lammel, EM1
Leeper, DB; Martin, JH; Rowley, R1
DeDonato, V; Ramzan, I1
Dozi-Vassiliades, J; Hatzitheodoridou, P; Kourakis, A; Mourelatos, D; Tsiouris, J1
Jaques, R; Rüegg, M1
Levine, BB; May, CD; Weissmann, G1
Cohen, BM2
Abelson, DM; Boyle, A1
Baethmann, A; Brendel, W; Reulen, HJ1
Akiyama, M; Goto, F1
Sugimoto, I4
Brenner, G; Trautmann, H1
Alberto, R; Lyman, M; May, CD1
Dalton, C; Dwyer, JX; VanTrabert, TC1
Chilcote, DD; Mrochek, JE1
Carmichael, WM1
Bradshaw, RA; Frazier, WA; Hogue-Angeletti, RA1
Adewunmi, AI; Enwonwu, CO; Okolie, EE1
Sandler, S; Swenne, I1
Amamoo, DG; Bernofsky, C1
Moss, J; Stanley, SJ; Watkins, PA1
Burzio, LO; Cornejo, R; Sáez, L1
Althaus, FR; Lawrence, SD; Pitot, HC; Sattler, GL1
Kawamura, A; Okamoto, H; Uchigata, Y; Yamamoto, H1
Williams, GT1
Heflich, RH; Morris, SM1
Bump, E; Datta, R; Hass, R; Kufe, D; Manome, Y; Shafman, T; Taneja, N; Weichselbaum, R1
Andersson, A; Korsgren, O; Sandler, S1
Guichard, M; Hodgkiss, RJ; Stern, S1
Bussink, J; Hodgkiss, RJ; Kaanders, JH; Marres, HA; Peters, JP; Rijken, PF; van der Kogel, AJ1
Castro, GD; Castro, JA; Costantini, MH; Delgado de Layño, AM1
NAKAMORI, Y; SEKIGUCHI, K; UEDA, Y1
GHIA, G; MEREU, D1
FREZZA, S; MACCARINI, PA1
Chester, TL; Stalcup, AM1
Cohen, JD; Gallegos, AC; Lau, SS; Mastrandrea, NJ; Monks, TJ; Tham, KY1
Allende-Castro, C; Bustamante, D; Esmar, D; Espina-Marchant, P; Gebicke-Haerter, PJ; Gutierrez-Hernandez, MA; Herrera-Marschitz, M; Morales, P; Neira, T; Rojas-Mancilla, E; Valdes, JL1
Hirakura, Y; Terada, K; Teramura, T; Yamashita, H; Yuda, M1
Arora, KK; Suryanarayanan, R; Thakral, S1
Aaltonen, J; Ervasti, T; Ketolainen, J1
Churakov, AV; Drozd, KV; Manin, AN; Perlovich, GL1
Fábián, L; Guo, M; Li, M; Qiao, N; Sadiq, G; Wang, K1
Nagy, S; Pál, S; Salem, A; Széchenyi, A1
Gajda, M; Karolewicz, B; Nartowski, KP; Pluta, J1
Chadha, R; Chakraborti, S; Grewal, MK; Jindal, A; Tomar, S1
Cross, RBM; Kirubakaran, P; Li, M; Rosbottom, I; Wang, K1

Reviews

2 review(s) available for niacinamide and theophylline

ArticleYear
[Critical review on vasodilators].
    Jibi inkoka Otolaryngology, 1969, Volume: 40, Issue:10

    Topics: Adenosine Triphosphate; Alcohols; Alkaloids; Antihypertensive Agents; Imidazoles; Inositol; Kallikreins; Mandelic Acids; Niacinamide; Nicotinic Acids; Nucleosides; Organ Specificity; Papaverine; Plants, Medicinal; Rauwolfia; Theophylline; Vasodilator Agents

1969
Nerve growth factor and insulin: evidence of similarities in structure, function, and mechanism of action.
    Recent progress in hormone research, 1974, Volume: 30, Issue:0

    Topics: Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Biological Assay; Bucladesine; Chick Embryo; Disulfides; Ganglia; Insulin; Nerve Growth Factors; Niacinamide; Oxidation-Reduction; Protein Binding; Protein Conformation; Succinates; Theophylline; Tryptophan

1974

Other Studies

59 other study(ies) available for niacinamide and theophylline

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
7-Substituted theophyllines. Part I. Nicotinamide derivatives.
    Il Farmaco; edizione scientifica, 1979, Volume: 34, Issue:4

    Topics: Acetylcholine; Aminophylline; Animals; Female; Guinea Pigs; Heart; Histamine Antagonists; Ileum; Male; Mice; Niacinamide; Theophylline

1979
Poly(adenosine diphosphate ribose) polymerase activity and nicotinamide adenine dinucleotide in differentiating cardiac muscle.
    The Biochemical journal, 1976, Feb-15, Volume: 154, Issue:2

    Topics: Adenosine Triphosphate; Animals; Bucladesine; Caffeine; Cell Differentiation; Cell Nucleus; Dactinomycin; DNA; DNA Nucleotidyltransferases; Heart; Isoproterenol; Myocardium; N-Glycosyl Hydrolases; NAD; NAD+ Nucleosidase; Niacinamide; Proteins; Rats; Theophylline; Thymidine; Xanthines

1976
The action of streptozotocin in mouse leukaemia cells.
    Biochemical Society transactions, 1976, Volume: 4, Issue:4

    Topics: Animals; Cell Line; Kinetics; Leukemia, Experimental; Mice; NAD; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Streptozocin; Theophylline

1976
Inhibition of adenosine 3',5'-cyclic monophosphate phosphodiesterase by nicotinic acid [proceedings].
    Biochemical Society transactions, 1979, Volume: 7, Issue:5

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Brain; Liver; Male; Myocardium; Niacinamide; Nicotinic Acids; Organ Specificity; Rats; Theophylline

1979
Inhibition of adenosine 3',5'-monophosphate phosphodiesterase by nicotinamide and its homologues in vitro.
    Physiological chemistry and physics, 1975, Volume: 7, Issue:2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cyclic AMP; Esters; Hydrogen-Ion Concentration; Liver; Male; Niacinamide; Nicotinic Acids; Papaverine; Phosphodiesterase Inhibitors; Rats; Theophylline; Tritium

1975
Reversal and inhibition of cholera toxin-induced secretion in isolated rabbit ileum.
    The Journal of physiology, 1990, Volume: 421

    Topics: Adenine; Animals; Bacterial Toxins; Benzamides; Cholera Toxin; Enterotoxins; Escherichia coli; Escherichia coli Proteins; Hypoxanthines; Ileum; In Vitro Techniques; Intestinal Absorption; Methionine; Niacinamide; Rabbits; Theophylline

1990
Tissue culture of human fetal pancreas. Effects of nicotinamide on insulin production and formation of isletlike cell clusters.
    Diabetes, 1989, Volume: 38 Suppl 1

    Topics: Culture Techniques; Female; Glucose; Humans; Insulin; Islets of Langerhans; Niacinamide; Pancreas; Pregnancy; Proinsulin; Theophylline

1989
NAD metabolism and induction of tyrosine aminotransferase in the rat.
    The International journal of biochemistry, 1985, Volume: 17, Issue:2

    Topics: Adrenalectomy; Animals; Brain; Enzyme Induction; Kidney; Liver; Male; NAD; Niacinamide; Organ Specificity; Oxidation-Reduction; Prednisolone; Rats; Rats, Inbred Strains; Spleen; Theophylline; Tyrosine Transaminase

1985
Hydrogen peroxide-induced injury of cells and its prevention by inhibitors of poly(ADP-ribose) polymerase.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:13

    Topics: Actin Cytoskeleton; Actins; Adenosine Triphosphate; Animals; Benzamides; Calcium; Cell Line; Cell Survival; DNA Repair; Humans; Hydrogen Peroxide; In Vitro Techniques; Lymphocytes; Macrophages; Mice; NAD; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Theophylline

1986
Trypanosoma cruzi: differentiation to metacyclic trypomastigotes in the presence of ADP-ribosyltransferase inhibitors.
    Experimental parasitology, 1987, Volume: 64, Issue:3

    Topics: Animals; Benzamides; Chagas Disease; Mice; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Theophylline; Triatoma; Trypanosoma cruzi

1987
Effect of poly(adenosinediphosphoribose) synthesis inhibitors and structurally related compounds on radiation-induced G2 arrest.
    Radiation research, 1988, Volume: 113, Issue:1

    Topics: Aminobenzoates; Animals; Benzamides; Caffeine; Cell Line; Cricetinae; Deoxyadenosines; Interphase; meta-Aminobenzoates; Niacin; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Theophylline

1988
Effect of nicotinamide on theophylline seizures in rats.
    Biochemical pharmacology, 1988, Mar-15, Volume: 37, Issue:6

    Topics: Animals; Male; Niacinamide; Rats; Rats, Inbred Strains; Seizures; Theophylline

1988
Synergistic induction of sister-chromatid exchanges in lymphocytes from normal subjects and from patients under cytostatic therapy by inhibitors of poly(ADP-ribose)polymerase and antitumour agents.
    Mutation research, 1985, Volume: 143, Issue:4

    Topics: Antineoplastic Agents; DNA Repair; Drug Synergism; Humans; In Vitro Techniques; Lymphocytes; NAD+ Nucleosidase; Neoplasms; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Sister Chromatid Exchange; Theophylline

1985
Tribenoside as an inhibitor of chemically induced histamine release.
    Experientia, 1974, Apr-15, Volume: 30, Issue:4

    Topics: Adrenocorticotropic Hormone; Animals; Benzyl Compounds; Citrates; Cromolyn Sodium; Diethylcarbamazine; Flufenamic Acid; Glucose; Glycosides; Histamine H1 Antagonists; Histamine Release; Isoproterenol; Lysine; Male; Mast Cells; Niacinamide; Nikethamide; Norepinephrine; p-Methoxy-N-methylphenethylamine; Phenylbutazone; Phloretin; Serine; Sodium; Sodium Salicylate; Theophylline

1974
Effects of compounds which inhibit antigenic release of histamine and phagocytic release of lysosomal enzyme on glucose utilization by leukocytes in humans.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1970, Volume: 133, Issue:3

    Topics: Adenine Nucleotides; Antigens; Carbon Dioxide; Carbon Isotopes; Caseins; Cyclic AMP; Depression, Chemical; Ethanol; Glucose; Glucuronidase; Histamine Release; Humans; In Vitro Techniques; Lactoglobulins; Leukocytes; Lysosomes; Niacinamide; Phagocytosis; Pollen; Theophylline; Zymosan

1970
A niacinamide-theophylline compound (RC-C-144). I. Human absorption and blood level studies.
    The Journal of asthma research, 1966, Volume: 4, Issue:1

    Topics: Adult; Aged; Asthma; Bronchitis; Female; Humans; Male; Middle Aged; Niacinamide; Pulmonary Emphysema; Theophylline

1966
A niacinamide-theophylline compound (RC-C-144). II. Clinical and spirometric effects.
    The Journal of asthma research, 1966, Volume: 4, Issue:1

    Topics: Adult; Aged; Asthma; Bronchitis; Female; Humans; Male; Middle Aged; Niacinamide; Pulmonary Emphysema; Theophylline

1966
Spectrophotometric determination of plasma pyridones in man following nicotinamide administration, with a general note on the quantitative treatment of interfering substances in analytical methods.
    Clinica chimica acta; international journal of clinical chemistry, 1966, Volume: 14, Issue:4

    Topics: Caffeine; Humans; Niacinamide; Pyridones; Spectrophotometry; Theophylline

1966
[The effect of the Antimetabolite 6-aminonicotinamide (6-ANA) on the water- and electrolyte content in the brain of rats and its inhibition by niacin].
    Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimentelle Chirurgie, 1968, Volume: 146, Issue:3

    Topics: Animals; Biological Transport, Active; Brain; Brain Edema; Myocardium; Niacinamide; Nicotinic Acids; Potassium; Rats; Sodium; Theophylline; Water; Water-Electrolyte Balance

1968
Studies on complexes. 13. Effect of complex formation on drug absorption from alimentary tract. (4).
    Chemical & pharmaceutical bulletin, 1968, Volume: 16, Issue:8

    Topics: Aminosalicylic Acids; Animals; Caffeine; Drug Compounding; Intestinal Absorption; Intestine, Small; Kinetics; Niacinamide; Oxazoles; Pyridazines; Rats; Theophylline

1968
Studies on complexes. XIV. Effect of complex formation on drug absorption from alimentary tract. (5). Enhancing the absorption of certain drugs by complex formation.
    Chemical & pharmaceutical bulletin, 1969, Volume: 17, Issue:5

    Topics: Animals; Antipyrine; Caffeine; Indoles; Intestinal Absorption; Intestine, Small; Niacinamide; Rats; Salicylates; Theophylline

1969
Studies on complexes. XVI. Effect of complex formation on drug absorption from alimentary tract. (6). Some factors affecting complex absorption.
    Chemical & pharmaceutical bulletin, 1969, Volume: 17, Issue:7

    Topics: Aminosalicylic Acids; Animals; Caffeine; Drug Synergism; Hydrogen-Ion Concentration; Intestinal Absorption; Intestine, Small; Niacinamide; Perfusion; Rats; Stimulation, Chemical; Theophylline

1969
[Effect of xanthinol-nicotinate on detoxification processes in liver. Experimental studies on the model of hexobarbital-narcosis in rat].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:12

    Topics: Anesthesia, General; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Depression, Chemical; Female; Hexobarbital; Liver; Male; Niacinamide; Nicotinic Acids; Pyridines; Rats; Sex Factors; Sleep; Theophylline; Time Factors

1969
Studies on complexes. XX. Effect of complex formation on drug absorption from alimentary tract.
    Chemical & pharmaceutical bulletin, 1970, Volume: 18, Issue:3

    Topics: Adrenochrome; Animals; Caffeine; Chelating Agents; Gastric Mucosa; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Male; Niacinamide; Rats; Theophylline

1970
Effects of compounds which inhibit lymphocyte stimulation on the utilization of glucose by leukocytes.
    The Journal of allergy, 1970, Volume: 46, Issue:1

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Carbon Isotopes; Chloroquine; Colchicine; Culture Media; Culture Techniques; Ethanol; Glucose; Humans; Hydrocortisone; Lectins; Leukocytes; Lymphocyte Activation; Lymphocytes; Niacinamide; Ouabain; Theophylline; Time Factors; Tritium

1970
Relationship of nicotinamide and nicotinic acid to hypolipidemia.
    Biochemical pharmacology, 1970, Volume: 19, Issue:9

    Topics: Adipose Tissue; Animals; Cholesterol; Fasting; Fatty Acids, Nonesterified; Lipids; Male; Niacinamide; Nicotinic Acids; Nucleotides; Pyridines; Rats; Theophylline; Time Factors; Triglycerides

1970
Use of automatic digital data acquisition and on-line computer analysis in high-resolution liquid chromatography.
    Clinical chemistry, 1971, Volume: 17, Issue:8

    Topics: Autoanalysis; Chromatography; Computers; Cyclic N-Oxides; Hippurates; Hypoxanthines; Mathematics; Methods; Niacinamide; Nicotinic Acids; Orotic Acid; Pyrimidines; Ribonucleosides; Spectrophotometry; Theophylline; Ultraviolet Rays; Uracil; Uric Acid; Xanthines

1971
The determination of nikethamide and other compounds in pharmaceutical dosage forms by thin-layer chromatography.
    The Analyst, 1971, Volume: 96, Issue:147

    Topics: Adenosine; Caffeine; Chromatography, Thin Layer; Dosage Forms; Gels; Methods; Niacinamide; Silicon Dioxide; Solvents; Spectrophotometry; Strychnine; Theophylline; Ultraviolet Rays

1971
Antimalarial activity of inhibitors of ADP-ribosyl transferase against Plasmodium yoelii infection in mice. 1. Preliminary data.
    Acta tropica, 1982, Volume: 39, Issue:3

    Topics: Animals; Antimalarials; Benzamides; Chloroquine; Drug Evaluation, Preclinical; Malaria; Male; Mice; Niacinamide; Nucleotidyltransferases; Plasmodium; Poly(ADP-ribose) Polymerases; Theobromine; Theophylline

1982
Streptozotocin, but not alloxan, induces DNA repair synthesis in mouse pancreatic islets in vitro.
    Diabetologia, 1983, Volume: 25, Issue:5

    Topics: Alloxan; Animals; DNA Repair; DNA Replication; Islets of Langerhans; Methylurea Compounds; Mice; Mice, Inbred Strains; Niacinamide; Streptozocin; Theophylline

1983
ADP-ribosylation of isolated rat islets of Langerhans.
    Biochemical and biophysical research communications, 1984, Jan-30, Volume: 118, Issue:2

    Topics: Adenosine Diphosphate Ribose; Animals; Arginine; Cell Membrane; In Vitro Techniques; Islets of Langerhans; Kinetics; NAD; Niacinamide; Nucleoside Diphosphate Sugars; Rats; Rats, Inbred Lew; Theophylline; Tritium

1984
Isolation and properties of an NAD- and guanidine-dependent ADP-ribosyltransferase from turkey erythrocytes.
    The Journal of biological chemistry, 1980, Jun-25, Volume: 255, Issue:12

    Topics: Animals; Erythrocytes; Guanidines; Kinetics; NAD; Niacinamide; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases; Theophylline; Thymidine; Turkeys

1980
Poly (ADP-ribose) synthetase activity in rat testis mitochondria.
    Biochemical and biophysical research communications, 1981, Nov-16, Volume: 103, Issue:1

    Topics: Animals; Brain; Cattle; Cricetinae; Digitonin; Kinetics; Male; Mitochondria; Mitochondria, Liver; NAD+ Nucleosidase; Niacinamide; Organ Specificity; Poly(ADP-ribose) Polymerases; Rats; Species Specificity; Spermatozoa; Testis; Theophylline; Thymidine

1981
ADP-ribosyltransferase activity in cultured hepatocytes. Interactions with DNA repair.
    The Journal of biological chemistry, 1982, May-25, Volume: 257, Issue:10

    Topics: Animals; Cells, Cultured; DNA Repair; DNA Replication; Kinetics; Liver; Male; Niacinamide; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases; Rats; Spermine; Theophylline

1982
Protection by superoxide dismutase, catalase, and poly(ADP-ribose) synthetase inhibitors against alloxan- and streptozotocin-induced islet DNA strand breaks and against the inhibition of proinsulin synthesis.
    The Journal of biological chemistry, 1982, Jun-10, Volume: 257, Issue:11

    Topics: Alloxan; Amides; Animals; Benzamides; Catalase; DNA Replication; Glutathione; In Vitro Techniques; Islets of Langerhans; Male; NAD+ Nucleosidase; Niacinamide; Picolinic Acids; Poly(ADP-ribose) Polymerase Inhibitors; Proinsulin; Rats; Rats, Inbred Strains; Streptozocin; Superoxide Dismutase; Theophylline

1982
Trypanosoma cruzi: inhibition of intracellular and extracellular differentiation by ADP-ribosyl transferase antagonists.
    Experimental parasitology, 1983, Volume: 56, Issue:3

    Topics: Animals; Benzamides; Cell Differentiation; Mice; Niacinamide; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases; Theophylline; Trypanosoma cruzi

1983
A comparison of the toxic and SCE-inducing effects of inhibitors of ADP-ribosyl transferase in Chinese hamster ovary cells.
    Mutation research, 1984, Volume: 126, Issue:1

    Topics: Adenosine Diphosphate Ribose; Alkylating Agents; Animals; Benzamides; Cell Survival; Cells, Cultured; Cricetinae; Crossing Over, Genetic; Drug Synergism; Female; Niacinamide; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases; Sister Chromatid Exchange; Theophylline

1984
Coinduction of c-jun gene expression and internucleosomal DNA fragmentation by ionizing radiation.
    Biochemistry, 1993, Oct-12, Volume: 32, Issue:40

    Topics: Cell Line; DNA; DNA Damage; Gene Expression; Genes, jun; Humans; Hydrogen Peroxide; Niacinamide; Nucleosomes; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Theophylline; X-Rays

1993
Pretreatment of fetal porcine pancreas in culture with nicotinamide accelerates reversal of diabetes after transplantation to nude mice.
    Surgery, 1993, Volume: 113, Issue:2

    Topics: Alloxan; Animals; Blood Glucose; Cell Differentiation; Cells, Cultured; Diabetes Mellitus, Experimental; DNA; Glucose; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Mice; Mice, Nude; Niacinamide; Oxidation-Reduction; Swine; Theophylline

1993
Comparison of two techniques for detecting tumour hypoxia: a fluorescent immunochemical method and an in vitro colony assay.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1996, Volume: 39, Issue:2

    Topics: Adenocarcinoma; Animals; Carbon Dioxide; Cell Hypoxia; Cell Survival; Cesium Radioisotopes; DNA Damage; DNA, Neoplasm; Drug Combinations; Emulsions; Female; Fluorescent Antibody Technique, Indirect; Fluorocarbons; Humans; Hydrocarbons, Brominated; Mammary Neoplasms, Animal; Mice; Mice, Nude; Niacinamide; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Rectal Neoplasms; Theophylline; Tumor Cells, Cultured; Tumor Stem Cell Assay

1996
Vascular architecture and microenvironmental parameters in human squamous cell carcinoma xenografts: effects of carbogen and nicotinamide.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1999, Volume: 50, Issue:2

    Topics: Animals; Benzimidazoles; Blood Vessels; Carbon Dioxide; Carcinoma, Squamous Cell; Cell Division; Endothelium, Vascular; Humans; Hypoxia; Laryngeal Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Niacinamide; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Theophylline; Transplantation, Heterologous; Tumor Cells, Cultured

1999
Rat ventral prostate xanthine oxidase bioactivation of ethanol to acetaldehyde and 1-hydroxyethyl free radicals: analysis of its potential role in heavy alcohol drinking tumor-promoting effects.
    Teratogenesis, carcinogenesis, and mutagenesis, 2001, Volume: 21, Issue:2

    Topics: Acetaldehyde; Alcohol Drinking; Allopurinol; Animals; Antimetabolites; Caffeine; Carcinogens; Chromatography, Gas; Cytosol; Diet; Enzyme Inhibitors; Ethanol; Free Radicals; Gas Chromatography-Mass Spectrometry; Hypoxanthine; Male; Meat; NAD; Neoplasms; Niacinamide; Phosphodiesterase Inhibitors; Prostate; Prostatic Neoplasms; Purines; Rats; Rats, Sprague-Dawley; Spin Trapping; Temperature; Theobromine; Theophylline; Time Factors; Vasodilator Agents; Xanthine; Xanthine Oxidase

2001
STUDIES ON THE METHOD OF THERMAL ANALYSIS OF ORGANIC MEDICINALS. III. RELATIONS BETWEEN METHODS OF SAMPLE PREPARATION AND OBTAINED PHASE DIAGRAMS.
    Chemical & pharmaceutical bulletin, 1963, Volume: 11

    Topics: 4-Aminobenzoic Acid; Aminopyrine; Ammonium Compounds; Aniline Compounds; Barbiturates; Benzoates; Biphenyl Compounds; Caffeine; Chemistry Techniques, Analytical; Niacinamide; ortho-Aminobenzoates; Quaternary Ammonium Compounds; Research; Theophylline

1963
[CLINICAL OBSERVATIONS AND THERAPEUTIC RESULTS IN SUBJECTS WITH ISCHEMIC CARDIOPATHY TREATED WITH AN ENZYME COMPLEX ASSOCIATED WITH A VASODILATOR DRUG].
    Gazzetta medica italiana, 1964, Volume: 123

    Topics: Adenosine Triphosphate; Coronary Disease; Drug Therapy; Electrocardiography; Flavin Mononucleotide; Myocardial Ischemia; NAD; Niacin; Niacinamide; Theophylline; Thiamine Pyrophosphate; Vasodilator Agents

1964
[ON THE CLINICAL VALUE OF COLLATERAL TROPHO-ENZYMATIC THERAPY IN ACUTE AND CHRONIC HEART DISEASES].
    Gazzetta medica italiana, 1964, Volume: 123

    Topics: Coenzymes; Coronary Disease; Heart Diseases; Humans; Hypertension; Khellin; Niacin; Niacinamide; Pulmonary Heart Disease; Theophylline; Vasodilator Agents

1964
Interactions between minimum run time, modifier concentration, and efficiency parameters in a high performance liquid chromatography separation.
    Journal of chromatography. A, 2011, Jan-14, Volume: 1218, Issue:2

    Topics: Chromatography, High Pressure Liquid; Methanol; Models, Chemical; Niacinamide; Pressure; Resorcinols; Theobromine; Theophylline; Time Factors; Uracil

2011
cAMP-dependent cytosolic mislocalization of p27(kip)-cyclin D1 during quinol-thioether-induced tuberous sclerosis renal cell carcinoma.
    Toxicological sciences : an official journal of the Society of Toxicology, 2011, Volume: 122, Issue:2

    Topics: Animals; Benzenesulfonates; Bucladesine; Carcinoma, Renal Cell; Cell Line; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; Cytosol; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Hydroquinones; Kidney Neoplasms; Male; Mice; Mice, Nude; Mitogen-Activated Protein Kinases; Niacinamide; Pentoxifylline; Phenylurea Compounds; Phosphodiesterase Inhibitors; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-raf; Pyridines; Rats; RNA, Small Interfering; Signal Transduction; Sorafenib; Theophylline; Tuberous Sclerosis; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins

2011
Further studies on the hypothesis of PARP-1 inhibition as a strategy for lessening the long-term effects produced by perinatal asphyxia: effects of nicotinamide and theophylline on PARP-1 activity in brain and peripheral tissue : nicotinamide and theophyl
    Neurotoxicity research, 2012, Volume: 22, Issue:1

    Topics: Animals; Animals, Newborn; Asphyxia; Asphyxia Neonatorum; Behavior, Animal; Brain; Heart; Humans; Infant, Newborn; Microdialysis; Models, Animal; Myocardium; Niacinamide; Phosphodiesterase Inhibitors; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Theophylline; Vitamin B Complex

2012
Detection of cocrystal formation based on binary phase diagrams using thermal analysis.
    Pharmaceutical research, 2013, Volume: 30, Issue:1

    Topics: Caffeine; Calorimetry, Differential Scanning; Camphor; Carbamazepine; Crystallization; Heating; Indomethacin; Niacinamide; Pharmaceutical Preparations; Phase Transition; Piroxicam; Powder Diffraction; Salicylic Acid; Theophylline; X-Ray Diffraction

2013
Instability in theophylline and carbamazepine hydrate tablets: cocrystal formation due to release of lattice water.
    Pharmaceutical research, 2013, Volume: 30, Issue:7

    Topics: Analgesics, Non-Narcotic; Bronchodilator Agents; Carbamazepine; Citric Acid; Crystallization; Humidity; Niacinamide; Phase Transition; Powder Diffraction; Solubility; Tablets; Theophylline; Water; X-Ray Diffraction

2013
Theophylline-nicotinamide cocrystal formation in physical mixture during storage.
    International journal of pharmaceutics, 2015, Volume: 486, Issue:1-2

    Topics: Calorimetry, Differential Scanning; Crystallization; Drug Storage; Humidity; Niacinamide; Powder Diffraction; Spectrum Analysis, Raman; Temperature; Theophylline; X-Ray Diffraction

2015
Drug-drug cocrystals of antituberculous 4-aminosalicylic acid: Screening, crystal structures, thermochemical and solubility studies.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2017, Mar-01, Volume: 99

    Topics: Aminosalicylic Acid; Antitubercular Agents; Caffeine; Crystallization; Crystallography, X-Ray; Drug Stability; Isoniazid; Models, Molecular; Niacinamide; Powder Diffraction; Pyrazinamide; Solubility; Theophylline; X-Ray Diffraction

2017
Insight into Flufenamic Acid Cocrystal Dissolution in the Presence of a Polymer in Solution: from Single Crystal to Powder Dissolution.
    Molecular pharmaceutics, 2017, 12-04, Volume: 14, Issue:12

    Topics: Anti-Inflammatory Agents; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Crystallization; Flufenamic Acid; Microscopy; Niacinamide; Polyethylene Glycols; Povidone; Powders; Solubility; Spectroscopy, Fourier Transform Infrared; Theophylline; X-Ray Diffraction

2017
Reliability of the Hansen solubility parameters as co-crystal formation prediction tool.
    International journal of pharmaceutics, 2019, Mar-10, Volume: 558

    Topics: Caffeine; Carbamazepine; Chemistry, Pharmaceutical; Crystallization; Niacinamide; Piroxicam; Solubility; Theophylline

2019
Tuning the cocrystal yield in matrix-assisted cocrystallisation via hot melt extrusion: A case of theophylline-nicotinamide cocrystal.
    International journal of pharmaceutics, 2019, Oct-05, Volume: 569

    Topics: Crystallization; Hot Melt Extrusion Technology; Hot Temperature; Niacinamide; Poloxamer; Polyethylene Glycols; Polyvinyls; Theophylline

2019
Cocrystals of diacerein: Towards the development of improved biopharmaceutical parameters.
    International journal of pharmaceutics, 2020, Jan-25, Volume: 574

    Topics: Anthraquinones; Biological Availability; Biological Products; Calorimetry, Differential Scanning; Crystallization; Niacinamide; Powder Diffraction; Solubility; Spectroscopy, Fourier Transform Infrared; Theophylline; X-Ray Diffraction

2020
Understanding the Effects of a Polymer on the Surface Dissolution of Pharmaceutical Cocrystals Using Combined Experimental and Molecular Dynamics Simulation Approaches.
    Molecular pharmaceutics, 2020, 02-03, Volume: 17, Issue:2

    Topics: Adsorption; Carbamazepine; Chemical Precipitation; Crystallization; Drug Compounding; Drug Liberation; Excipients; Flufenamic Acid; Molecular Dynamics Simulation; Niacinamide; Polyethylene Glycols; Povidone; Pyrrolidines; Solubility; Theophylline; Vinyl Compounds

2020