Compounds > niacinamide

niacinamide and srpin340

niacinamide has been researched along with srpin340 in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (66.67)24.3611
2020's3 (33.33)2.80

Authors

AuthorsStudies
Bates, DO; Dick, AD; Gammons, MV; Harper, SJ1
Bates, DO; Coupland, SE; Dean, R; Gammons, MV; Lucas, R; Oltean, S1
Denawa, M; Fukuhara, J; Furuya, T; Hagiwara, M; Hoshina, M; Hosoya, T; Ikura, T; Inoue, N; Ishida, S; Ito, N; Kii, I; Kojima, H; Morooka, S; Nagano, T; Ninomiya, K; Noda, K; Okabe, T; Okuno, Y; Yoshida, S; Yoshimura, N1
Almeida, MR; Barbosa, Éde A; Barros, MV; Borges, JC; Bressan, GC; de Oliveira, EB; de Oliveira, LL; Ferreira, JG; Fietto, JL; Júnior, AS; Kobarg, J; Laranjeira, AB; Polêto, MD; Righetto, GL; Salgado, RL; Seraphim, TV; Siqueira, RP; Teixeira, RR; Yunes, JA1
Almeida, MR; Barbosa, ÉAA; Barros, MVA; Bressan, GC; de Oliveira, LL; Fietto, JLR; Gonçalves, VHS; Onofre, TS; Pereira, HS; Silva Júnior, A; Siqueira, RP; Teixeira, RR1
Adjanohoun, ALM; Almeida, MR; Barbosa, ÉAA; Barros, MVA; Bressan, GC; Ferreira, RS; Fietto, JLR; Gonçalves, VHS; Júnior, AS; Lima, GDA; Loterio, RK; Machado-Neves, M; Marques-da-Silva, EA; Moreira, GA; Paiva, JC; Santos, VC; Siqueira, RP; Teixeira, RR; Viol, LCS1
Giannakouros, T; Koukiali, A; Koutroumani, M; Nikolakaki, E; Sigala, I1
Almeida, AA; Boroni, M; Bressan, GC; Caetano, MMM; de Andrade Barros, MV; de Oliveira Santos, L; de Oliveira, LL; de Paiva, JC; de Souza, APM; do Vale, JA; Fietto, JLR; Gonçalves, VHS; Guimarães, GR; Machado-Neves, M; Martim, FRG; Moreira, GA; Silva, LVG; Silva-Júnior, A; Teixeira, RR1
Bressan, GC; da Silva, EQG; de Almeida Lima, GD; de Melo Agripino, J; de Oliveira Mendes, TA; de Oliveira, LL; de Paiva, JC; de Souza, APM; Fietto, JLR; Machado-Neves, M; Mendes, FC; Moreira, GA; Santos, MR; Silva, LVG; Silva-Júnior, A; Teixeira, RR1

Other Studies

9 other study(ies) available for niacinamide and srpin340

ArticleYear
SRPK1 inhibition modulates VEGF splicing to reduce pathological neovascularization in a rat model of retinopathy of prematurity.
    Investigative ophthalmology & visual science, 2013, Aug-27, Volume: 54, Issue:8

    Topics: Animals; Blotting, Western; Cells, Cultured; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Humans; Infant, Newborn; Injections, Intraocular; Niacinamide; Piperidines; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Retinal Neovascularization; Retinopathy of Prematurity; Vascular Endothelial Growth Factor A

2013
Targeting SRPK1 to control VEGF-mediated tumour angiogenesis in metastatic melanoma.
    British journal of cancer, 2014, Jul-29, Volume: 111, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Gene Knockdown Techniques; Humans; Melanoma; Mice; Mice, Nude; Molecular Targeted Therapy; Neovascularization, Pathologic; Niacinamide; Piperidines; Protein Serine-Threonine Kinases; RNA Splicing; Skin Neoplasms; Tumor Burden; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2014
Identification of a Dual Inhibitor of SRPK1 and CK2 That Attenuates Pathological Angiogenesis of Macular Degeneration in Mice.
    Molecular pharmacology, 2015, Volume: 88, Issue:2

    Topics: Administration, Topical; Animals; Casein Kinase II; Cell Line; Choroidal Neovascularization; Crystallography, X-Ray; Disease Models, Animal; Enzyme Inhibitors; Humans; Macular Degeneration; Mice; Models, Molecular; Molecular Docking Simulation; Niacinamide; Piperidines; Protein Serine-Threonine Kinases; Pyrimidinones; Small Molecule Libraries; Structure-Activity Relationship; Thiadiazoles

2015
Potential Antileukemia Effect and Structural Analyses of SRPK Inhibition by N-(2-(Piperidin-1-yl)-5-(Trifluoromethyl)Phenyl)Isonicotinamide (SRPIN340).
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Antineoplastic Agents; Apoptosis; Binding Sites; Blotting, Western; Cell Survival; Cells, Cultured; Gene Expression Regulation, Leukemic; HeLa Cells; HL-60 Cells; Humans; Jurkat Cells; K562 Cells; Leukemia; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Niacinamide; Piperidines; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Reverse Transcriptase Polymerase Chain Reaction; Spectrometry, Fluorescence

2015
Trifluoromethyl arylamides with antileukemia effect and intracellular inhibitory activity over serine/arginine-rich protein kinases (SRPKs).
    European journal of medicinal chemistry, 2017, Jul-07, Volume: 134

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Humans; Leukemia; Niacinamide; Piperidines; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Vincristine

2017
Antimetastatic effect of the pharmacological inhibition of serine/arginine-rich protein kinases (SRPK) in murine melanoma.
    Toxicology and applied pharmacology, 2018, 10-01, Volume: 356

    Topics: Animals; Antineoplastic Agents; Cell Adhesion; Cell Movement; Drug Screening Assays, Antitumor; Female; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Neoplasm Invasiveness; Neoplasm Metastasis; Niacinamide; Piperidines; Protein Serine-Threonine Kinases; Tumor Stem Cell Assay

2018
Nuclear Translocation of SRPKs Is Associated with 5-FU and Cisplatin Sensitivity in HeLa and T24 Cells.
    Cells, 2021, 03-30, Volume: 10, Issue:4

    Topics: Ataxia Telangiectasia Mutated Proteins; Cell Death; Cell Nucleus; Cisplatin; Cytoprotection; DNA Damage; Fluorouracil; HeLa Cells; Humans; Models, Biological; Niacinamide; Phosphorylation; Piperidines; Protective Agents; Protein Serine-Threonine Kinases; Protein Transport

2021
The SRPK inhibitor N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl) isonicotinamide (SRPIN340) increases the immune response against metastatic melanoma in mice.
    Biochemical pharmacology, 2022, Volume: 203

    Topics: Animals; Humans; Immunity; Melanoma; Mice; Niacinamide; Piperidines; Protein Serine-Threonine Kinases; Skin Neoplasms; Tumor Microenvironment

2022
Immunomodulatory activity of trifluoromethyl arylamides derived from the SRPK inhibitor SRPIN340 and their potential use as vaccine adjuvant.
    Life sciences, 2022, Oct-15, Volume: 307

    Topics: Adjuvants, Immunologic; Adjuvants, Vaccine; Animals; Antibodies, Neutralizing; Antiviral Agents; Arginine; Dipeptides; Immunity; Mice; Niacinamide; Piperidines; Protein Isoforms; Protein Serine-Threonine Kinases; RNA Splicing Factors; Serine; Vaccines

2022