niacinamide has been researched along with sirtinol in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (30.77) | 29.6817 |
| 2010's | 18 (69.23) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Järvinen, T; Kyrylenko, S; Leppänen, J; Niskanen, P; Nyrönen, TH; Poso, A; Salminen, A; Tervo, AJ | 1 |
| Goekjian, P; Jochum, A; Jung, M; Kunick, C; Marshall, B; Meier, R; Saunders, L; Sippl, W; Trapp, J; Verdin, E | 1 |
| Hruby, H; Jung, M; Meier, R; Neugebauer, RC; Sippl, W; Uchiechowska, U; Valkov, V; Verdin, E | 1 |
| Berger, SL; Brent, M; Dang, W; Howitz, K; Jackson, B; Marmorstein, R; Sanders, BD; Schreiber, SL; Taylor, AM | 1 |
| Zheng, W | 1 |
| He, W; Jung, M; Maurer, B; Rumpf, T; Scharfe, M; Schmitt, ML; Sippl, W; Stolfa, DA; Verdin, E | 1 |
| He, B; Huang, W; Li, Y; Xie, T; You, L | 1 |
| He, B; Huang, W; Li, Y; Liu, J; You, L; Zhu, H | 1 |
| Chauhan, S; Kumar, A | 1 |
| Forgione, M; Hailu, GS; Mai, A; Robaa, D; Rotili, D; Sippl, W | 1 |
| Alcendor, RR; Imai, S; Kirshenbaum, LA; Sadoshima, J; Vatner, SF | 1 |
| Ahmad, N; Jung-Hynes, B; Nihal, M; Zhong, W | 1 |
| He, QY; Li, DD; Li, Y; Xu, R; Zhang, XM | 1 |
| Fujioka, H; Fujita, N; Hayashi, S; Ishida, K; Kubo, S; Kuroda, R; Kurosaka, M; Matsumoto, T; Matsushita, T; Sasaki, K; Takayama, K; Tei, K | 1 |
| Davidson, NE; Gu, Y; Li, H; Yao, Y; Zhou, Q | 1 |
| Black, JC; Boss, O; Dyson, NJ; Elson, SL; Hart, AC; Hirsch, ML; Israelian, K; Ji, JY; Jiang, K; Kadyk, LC; Li, X; Mostoslavsky, R; Mulligan, P; Näär, AM; Najafi-Shoushtari, H; Puigserver, P; Purushotham, A; Ribich, S; Rodgers, JT; Shioda, T; Smith, JJ; Thakur, JK; Walker, AK; Watts, JL; Westphal, CH; Whetstine, JR; Yang, F | 1 |
| Ancrenaz, V; Camins, A; Folch, J; Junyent, F; Pallàs, M; Pizarro, JG; Sureda, F; Verdaguer, E | 1 |
| Kang, YG; Kim, EC; Kim, SJ; Lee, SI; Lee, YM; Park, KH | 1 |
| Cheong, SA; Hyun, SH; Jeon, Y; Kwak, SS; Yoon, JD | 1 |
| Ji, M; Li, Y; Lin, Q; Lin, R; Ren, F; Wang, W; Zhang, J | 1 |
| Bai, L; Ji, M; Lin, R; Lu, Y; Qiao, H; Ren, F; Wang, W; Yang, L; Zhang, J | 1 |
| Gao, SJ; He, M; Li, Q; Ye, F; Zhou, F | 1 |
| Hu, J; Jing, H; Lin, H | 1 |
| Chang, YZ; Chen, MY; Hu, ML; Song, TY; Yang, NC | 1 |
| Ding, X; Hu, J; Ma, R; Xu, Y; Zhang, L | 1 |
| Li, YJ; Wang, YH; Zheng, GX | 1 |
4 review(s) available for niacinamide and sirtinol
| Article | Year |
|---|---|
Sirtuins as emerging anti-parasitic targets.
Topics: Animals; Antiparasitic Agents; Drug Delivery Systems; Enzyme Activation; Enzyme Inhibitors; Humans; Molecular Structure; Parasites; Sirtuins | 2013 |
How much successful are the medicinal chemists in modulation of SIRT1: A critical review.
Topics: Animals; Chemistry, Pharmaceutical; Drug Discovery; Enzyme Activation; Histone Deacetylase Inhibitors; Humans; Sirtuin 1 | 2016 |
Lysine Deacetylase Inhibitors in Parasites: Past, Present, and Future Perspectives.
Topics: Animals; Antiparasitic Agents; Drug Repositioning; Helminth Proteins; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Leishmania; Plasmodium; Protozoan Proteins; Schistosoma; Toxoplasma; Trypanosoma | 2017 |
Sirtuin inhibitors as anticancer agents.
Topics: Animals; Antineoplastic Agents; Benzamides; Enzyme Inhibitors; Humans; Naphthols; Neoplasms; Niacinamide; Protein Binding; Reactive Oxygen Species; Sirtuins | 2014 |
22 other study(ies) available for niacinamide and sirtinol
| Article | Year |
|---|---|
An in silico approach to discovering novel inhibitors of human sirtuin type 2.
Topics: Anthraquinones; Benzene Derivatives; Binding Sites; Crystallography, X-Ray; Databases, Factual; Models, Molecular; Molecular Structure; Phenols; Pyridines; Sirtuin 2; Sirtuins; Triazoles | 2004 |
Adenosine mimetics as inhibitors of NAD+-dependent histone deacetylases, from kinase to sirtuin inhibition.
Topics: Acetylation; Adenosine; Binding Sites; Cell Line, Tumor; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Models, Molecular; Molecular Mimicry; Protein Kinase Inhibitors; Sirtuins; Structure-Activity Relationship; Tubulin | 2006 |
Structure-activity studies on splitomicin derivatives as sirtuin inhibitors and computational prediction of binding mode.
Topics: Acetylation; Antineoplastic Agents; Catalytic Domain; Cell Line, Tumor; Databases, Factual; Drug Screening Assays, Antitumor; Humans; Hydrogen Bonding; Models, Molecular; Naphthalenes; Protein Binding; Pyrones; Recombinant Proteins; Sirtuin 2; Sirtuins; Stereoisomerism; Structure-Activity Relationship; Thermodynamics; Tubulin | 2008 |
Identification and characterization of novel sirtuin inhibitor scaffolds.
Topics: Drug Evaluation, Preclinical; Enzyme Inhibitors; Fibroblast Growth Factor 6; Fungal Proteins; Humans; Inhibitory Concentration 50; Kinetics; Sirtuins; Structure-Activity Relationship | 2009 |
Inhibitors of the NAD(+)-Dependent Protein Desuccinylase and Demalonylase Sirt5.
Topics: | 2012 |
A FRET-based assay for screening SIRT5 specific modulators.
Topics: Amino Acid Sequence; Coumarins; Enzyme Assays; Enzyme Inhibitors; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Kinetics; Molecular Sequence Data; p-Dimethylaminoazobenzene; Peptides; Sirtuins; Substrate Specificity | 2015 |
A FRET-based assay for screening SIRT6 modulators.
Topics: Coumarins; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Humans; Molecular Structure; Sirtuins; Structure-Activity Relationship | 2015 |
Silent information regulator 2alpha, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes.
Topics: Acetylation; Alkaloids; Animals; Apoptosis; Atrial Natriuretic Factor; Benzamides; Benzophenanthridines; Cell Nucleus; Cell Size; Cell Survival; Cells, Cultured; Culture Media, Serum-Free; Cysteine Proteinase Inhibitors; Dogs; Gene Silencing; Genes, Dominant; Genes, p53; Heart Failure; Heart Ventricles; Hydroxamic Acids; Hypertrophy; Hypertrophy, Left Ventricular; Longevity; Mice; Myocytes, Cardiac; Naphthols; Niacinamide; Phenanthridines; Protein Processing, Post-Translational; Rats; Rats, Wistar; Recombinant Fusion Proteins; Sirtuin 1; Sirtuins; Transcription, Genetic; Tumor Suppressor Protein p53 | 2004 |
Role of sirtuin histone deacetylase SIRT1 in prostate cancer. A target for prostate cancer management via its inhibition?
Topics: Adult; Aged; Benzamides; Cell Line, Tumor; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation, Developmental; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Male; Middle Aged; Naphthols; Neoplasm Proteins; Niacinamide; Prostatic Neoplasms; Sirtuin 1; Sirtuins; Vitamin B Complex | 2009 |
[Mechanism of apoptosis induced by SIRT1 deacetylase inhibitors in human breast cancer MCF-7 drug-resistant cells].
Topics: Apoptosis; Benzamides; Breast Neoplasms; Caspases; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Humans; Naphthols; Niacinamide; Sirtuin 1 | 2008 |
SIRT1 regulation of apoptosis of human chondrocytes.
Topics: Adult; Apoptosis; bcl-2-Associated X Protein; Benzamides; Case-Control Studies; Caspase 3; Caspase 9; Cells, Cultured; Chondrocytes; Enzyme Inhibitors; Humans; Male; Naphthols; Niacinamide; Nitric Oxide; Osteoarthritis, Knee; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Resveratrol; RNA, Small Interfering; Sirtuin 1; Sirtuins; Stilbenes | 2009 |
Inhibition of SIRT1 deacetylase suppresses estrogen receptor signaling.
Topics: Animals; Benzamides; Breast Neoplasms; Cell Line, Tumor; Cells, Cultured; Estradiol; Estrogen Receptor alpha; Female; Fibroblasts; Humans; Mammary Glands, Animal; Mice; Mice, Knockout; Naphthols; Neoplasm Proteins; Niacinamide; Promoter Regions, Genetic; Recombinant Fusion Proteins; RNA, Messenger; RNA, Neoplasm; RNA, Small Interfering; Signal Transduction; Sirtuin 1; Specific Pathogen-Free Organisms; Transcription, Genetic | 2010 |
Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP.
Topics: Acetylation; Animals; Benzamides; Caenorhabditis elegans; Cell Line; Cholesterol; Down-Regulation; Fasting; HeLa Cells; Heterocyclic Compounds, 4 or More Rings; Humans; Lipids; Mice; Naphthols; Niacinamide; Protein Stability; Sirtuin 1; Sirtuins; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2 | 2010 |
Resveratrol inhibits proliferation and promotes apoptosis of neuroblastoma cells: role of sirtuin 1.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Benzamides; Cell Cycle; Cell Line, Tumor; Cell Proliferation; DNA Fragmentation; Humans; Naphthols; Neuroblastoma; NF-kappa B; Niacinamide; Proto-Oncogene Proteins c-akt; Resveratrol; Sirtuin 1; Stilbenes; Tumor Suppressor Protein p53; Vitamin B Complex | 2011 |
Mechanical stress-activated immune response genes via Sirtuin 1 expression in human periodontal ligament cells.
Topics: Acetylcysteine; Benzamides; Cell Line; Chemokines; Cytokines; Defensins; Extracellular Signal-Regulated MAP Kinases; Glutathione; Humans; JNK Mitogen-Activated Protein Kinases; Naphthols; NF-kappa B; Niacinamide; p38 Mitogen-Activated Protein Kinases; Periodontal Ligament; Protein Kinase C; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Resveratrol; RNA Interference; Signal Transduction; Sirtuin 1; Stilbenes; Stress, Mechanical; Toll-Like Receptors | 2012 |
Expression patterns of sirtuin genes in porcine preimplantation embryos and effects of sirtuin inhibitors on in vitro embryonic development after parthenogenetic activation and in vitro fertilization.
Topics: Animals; Benzamides; Blastocyst; Embryo Culture Techniques; Embryonic Development; Fertilization in Vitro; Gene Expression Profiling; Naphthols; Niacinamide; Nuclear Transfer Techniques; Parthenogenesis; RNA, Messenger; Sirtuins; Swine | 2012 |
PPARα agonist fenofibrate attenuates TNF-α-induced CD40 expression in 3T3-L1 adipocytes via the SIRT1-dependent signaling pathway.
Topics: 3T3-L1 Cells; Adipocytes; AMP-Activated Protein Kinases; Animals; Benzamides; Blotting, Western; CD40 Antigens; Fenofibrate; Mice; Naphthols; NF-kappa B; Niacinamide; Oxazoles; PPAR alpha; Pyrrolidines; RNA, Messenger; Signal Transduction; Sirtuin 1; Thiocarbamates; Tumor Necrosis Factor-alpha; Tyrosine | 2013 |
The protective effect of fenofibrate against TNF-α-induced CD40 expression through SIRT1-mediated deacetylation of NF-κB in endothelial cells.
Topics: Acetylation; Antioxidants; Benzamides; CD40 Antigens; Cells, Cultured; Fenofibrate; Human Umbilical Vein Endothelial Cells; Humans; Hypolipidemic Agents; Inflammation; Naphthols; Niacinamide; Oxazoles; PPAR alpha; Pyrrolidines; RNA Interference; RNA, Small Interfering; Signal Transduction; Sirtuin 1; Thiocarbamates; Transcription Factor RelA; Tumor Necrosis Factor-alpha; Tyrosine; Up-Regulation | 2014 |
Activation of Kaposi's sarcoma-associated herpesvirus (KSHV) by inhibitors of class III histone deacetylases: identification of sirtuin 1 as a regulator of the KSHV life cycle.
Topics: Benzamides; Blotting, Western; Cell Line, Tumor; Chromatin Immunoprecipitation; DNA Primers; Gene Expression Regulation, Viral; Gene Knockdown Techniques; Herpesvirus 8, Human; Humans; Immediate-Early Proteins; Immunoprecipitation; Luciferases; Microscopy, Confocal; Naphthols; Niacinamide; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Sirtuin 1; Trans-Activators; Virus Activation; Virus Latency | 2014 |
Up-regulation of nicotinamide phosphoribosyltransferase and increase of NAD+ levels by glucose restriction extend replicative lifespan of human fibroblast Hs68 cells.
Topics: Acrylamides; Benzamides; Cell Line; Cell Proliferation; Cell Survival; Cells, Cultured; Cellular Senescence; Cytokines; Dose-Response Relationship, Drug; Fibroblasts; Glucose; Humans; NAD; Naphthols; Niacinamide; Nicotinamide Phosphoribosyltransferase; Piperidines; Sirtuin 1; Up-Regulation | 2015 |
Sirtuin Inhibition Adversely Affects Porcine Oocyte Meiosis.
Topics: Actins; Animals; Benzamides; Cell Polarity; Chromosomes, Mammalian; Cumulus Cells; Female; Histone Deacetylase Inhibitors; Meiosis; Naphthols; Niacinamide; Oocytes; Ovary; Polar Bodies; Primary Cell Culture; Sirtuins; Spindle Apparatus; Swine | 2015 |
Giardia duodenalis GlSir2.2, homolog of SIRT1, is a nuclear-located and NAD(+)-dependent deacethylase.
Topics: Amino Acid Sequence; Benzamides; Cell Nucleus; Fluorescent Antibody Technique, Indirect; Giardia lamblia; Group III Histone Deacetylases; Humans; Inhibitory Concentration 50; Naphthalenes; Naphthols; Niacinamide; Phylogeny; Pyrones; Sequence Alignment; Sirtuins | 2016 |