niacinamide and quinoxalines

niacinamide has been researched along with quinoxalines in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19903 (17.65)18.7374
1990's2 (11.76)18.2507
2000's3 (17.65)29.6817
2010's7 (41.18)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Ayrton, AD; Bass, SL; Flatt, PR; Ioannides, C; Trinick, J; Walker, R1
Neurath, G1
Ryley, JF; Wilson, RG1
Brown, JC; Burns, DM; Dykes, EL; Flitney, FW; Hirst, DG; Kennovin, GD; Ruddock, MW1
Gage, AT; Reyes, M; Stanton, PK1
Di Girolamo, N; Heywood, GJ; Thomas, PS; Wei, XM1
Lee, F; Richmond, A; Smykla, R; Thu, YM; Yang, J; Zaja-Milatovic, S1
Bouska, JJ; Fry, EH; Giranda, VL; Johnson, EF; Liu, X; Luo, Y; Miyashiro, J; Olson, AM; Park, CH; Penning, TD; Shi, Y; Woods, KW1
Dong, H; Hao, F; Miao, C; Sun, L; Zhang, H; Zhao, S1
Baudot, R; Cren-Olivé, C; Feidt, C; Fratta, C; Lazartigues, A; Thomas, M; Wiest, L1
Antilla, JC; Bickford, PC; Engberg, ME; Hudson, CE; Kang, CW; Lambert, CS; Philpot, RM; Rowell, PP; Wecker, L; Zesiewicz, TA1
Buhrmann, C; Busch, F; Shakibaei, M; Shayan, P1
Arimoto, T; Fujii, T; Fukuda, T; Ikeda, Y; Inaba, K; Kashiyama, T; Kawana, K; Kuramoto, H; Miyasaka, A; Oda, K; Osuga, Y; Sone, K; Uehara, Y; Wada-Hiraike, O; Yano, T1
Aoki, K; Arimoto, T; Fujii, T; Fukuda, T; Ikeda, Y; Inaba, K; Kashiyama, T; Kawana, K; Makii, C; Miyasaka, A; Oda, K; Osuga, Y; Sone, K; Wada-Hiraike, O; Yano, T1
Campana, F; Damstrup, L; Gandhi, L; Grande, E; Heist, RS; Hidalgo, M; Hyman, DM; Mita, MM; Schram, AM1
Arend, RC; Birrer, MJ; Chimiczewski, P; Davis, AM; Ghamande, S; O'Malley, DM; Provencher, D; Vergote, I1
Chen, MW; Li, X; Zhao, ZB; Zhao, ZK; Zhou, YG1

Reviews

1 review(s) available for niacinamide and quinoxalines

ArticleYear
[Nitrogen compounds of tobacco smoke].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:7

    Topics: Acridines; Alkaloids; Alkanes; Amines; Amino Acids; Aniline Compounds; Carbazoles; Cyanates; Indoles; Isoquinolines; Ketones; Niacinamide; Nicotiana; Nicotine; Nicotinic Acids; Nitriles; Nitrites; Nitrosamines; Piperidines; Plants, Toxic; Pyrazines; Pyridines; Pyrroles; Pyrrolidines; Quinolines; Quinoxalines; Smoking

1969

Trials

2 trial(s) available for niacinamide and quinoxalines

ArticleYear
A phase Ib dose-escalation and expansion study of the oral MEK inhibitor pimasertib and PI3K/MTOR inhibitor voxtalisib in patients with advanced solid tumours.
    British journal of cancer, 2018, Volume: 119, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Male; Middle Aged; Mitogen-Activated Protein Kinase Kinases; Neoplasms; Niacinamide; Phosphoinositide-3 Kinase Inhibitors; Quinoxalines; Sulfonamides; TOR Serine-Threonine Kinases

2018
EMR 20006-012: A phase II randomized double-blind placebo controlled trial comparing the combination of pimasertib (MEK inhibitor) with SAR245409 (PI3K inhibitor) to pimasertib alone in patients with previously treated unresectable borderline or low grade
    Gynecologic oncology, 2020, Volume: 156, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Double-Blind Method; Female; Humans; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Middle Aged; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasm Staging; Niacinamide; Ovarian Neoplasms; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Quinoxalines; Sulfonamides; TOR Serine-Threonine Kinases; Young Adult

2020

Other Studies

14 other study(ies) available for niacinamide and quinoxalines

ArticleYear
Streptozotocin-induced diabetes modulates the metabolic activation of chemical carcinogens.
    Chemico-biological interactions, 1988, Volume: 68, Issue:3-4

    Topics: Animals; Biotransformation; Carbolines; Carcinogens; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Experimental; Electrophoresis, Polyacrylamide Gel; Insulin; Isoenzymes; Male; Microsomes, Liver; Mixed Function Oxygenases; Molecular Weight; Mutagenicity Tests; Mutagens; Niacinamide; Quinolines; Quinoxalines; Rats; Rats, Inbred Strains

1988
Comparative studies with anticoccidials and three species of chicken coccidia in vivo and in vitro.
    The Journal of parasitology, 1972, Volume: 58, Issue:4

    Topics: Amprolium; Animals; Antiprotozoal Agents; Benzoates; Chickens; Coccidiosis; Culture Techniques; Eimeria; Kidney; Niacinamide; Poultry Diseases; Quinolines; Quinoxalines; Urea

1972
The effect of the vasodilator nicotinamide on cyclic nucleotide pathways in vascular smooth muscle.
    Biochemical Society transactions, 1997, Volume: 25, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Arteries; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Imines; In Vitro Techniques; Muscle, Smooth, Vascular; Niacinamide; Oxadiazoles; Phenylephrine; Phosphoric Diester Hydrolases; Quinoxalines; Rats; Rats, Wistar; Second Messenger Systems; Vasodilation; Vasodilator Agents

1997
Nitric-oxide-guanylyl-cyclase-dependent and -independent components of multiple forms of long-term synaptic depression.
    Hippocampus, 1997, Volume: 7, Issue:3

    Topics: Animals; Cyclic GMP; Electrophysiology; Enzyme Inhibitors; Guanylate Cyclase; Hippocampus; Long-Term Potentiation; Male; Neuronal Plasticity; Niacinamide; Nitric Oxide; Organ Culture Techniques; Oxadiazoles; Penicillamine; Platelet Aggregation Inhibitors; Quinoxalines; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Synapses; Thionucleotides

1997
Nicorandil inhibits the release of TNFalpha from a lymphocyte cell line and peripheral blood lymphocytes.
    International immunopharmacology, 2003, Volume: 3, Issue:12

    Topics: B-Lymphocytes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glyburide; Herpesvirus 4, Human; Humans; Immunoglobulin G; Leukocytes, Mononuclear; Niacinamide; Nicorandil; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Oxadiazoles; Pinacidil; Potassium Channels; Quinoxalines; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2003
Molecular determinants of melanoma malignancy: selecting targets for improved efficacy of chemotherapy.
    Molecular cancer therapeutics, 2009, Volume: 8, Issue:3

    Topics: Animals; Antineoplastic Agents; Benzenesulfonates; Biomarkers, Tumor; Dacarbazine; Drug Delivery Systems; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Melanoma; Mice; Mice, Inbred BALB C; Mice, Nude; Models, Biological; Niacinamide; Phenylurea Compounds; Pyridines; Quinoxalines; Skin Neoplasms; Sorafenib; Substrate Specificity; Temozolomide; Treatment Outcome; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2009
Synthesis and SAR of novel tricyclic quinoxalinone inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1).
    Bioorganic & medicinal chemistry letters, 2009, Aug-01, Volume: 19, Issue:15

    Topics: Antineoplastic Agents; Apoptosis; Cell Nucleus; Chemistry, Pharmaceutical; DNA Repair; Drug Design; Drug Screening Assays, Antitumor; Humans; Kinetics; Models, Molecular; Molecular Conformation; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Quinoxalines; Structure-Activity Relationship

2009
Nia1 and Nia2 are involved in exogenous salicylic acid-induced nitric oxide generation and stomatal closure in Arabidopsis.
    Journal of integrative plant biology, 2010, Volume: 52, Issue:3

    Topics: Arabidopsis; Arabidopsis Proteins; Cyclic ADP-Ribose; Cyclic GMP; Mutation; Niacinamide; Nitrate Reductase; Nitric Oxide; Nitroprusside; Oxadiazoles; Plant Stomata; Protein Kinase Inhibitors; Protein Kinases; Quinoxalines; Salicylic Acid; Signal Transduction

2010
Multiresidue method for the determination of 13 pesticides in three environmental matrices: water, sediments and fish muscle.
    Talanta, 2011, Sep-15, Volume: 85, Issue:3

    Topics: Acetamides; Aminoimidazole Carboxamide; Animals; Benzimidazoles; Carbamates; Chemical Fractionation; Chromatography, Liquid; Environmental Monitoring; Fishes; Geologic Sediments; Hydantoins; Isoxazoles; Methacrylates; Muscles; Naphthalenes; Niacinamide; Oxazolidinones; Pesticide Residues; Pesticides; Phenylurea Compounds; Propionates; Pyrimidines; Quinoxalines; Reproducibility of Results; Solid Phase Extraction; Strobilurins; Sulfonylurea Compounds; Tandem Mass Spectrometry; Thiophenes; Water Pollutants, Chemical

2011
Neuronal nicotinic receptor agonists improve gait and balance in olivocerebellar ataxia.
    Neuropharmacology, 2013, Volume: 73

    Topics: Animals; Ataxia; Benzazepines; Cerebellum; Dose-Response Relationship, Drug; Gait; Male; Mecamylamine; Motor Activity; Nerve Degeneration; Neural Pathways; Niacinamide; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Olivary Nucleus; Postural Balance; Pyridines; Quinoxalines; Rats; Rotarod Performance Test; Varenicline

2013
Sirtuin-1 (SIRT1) is required for promoting chondrogenic differentiation of mesenchymal stem cells.
    The Journal of biological chemistry, 2014, Aug-08, Volume: 289, Issue:32

    Topics: Acetylation; Cell Differentiation; Cells, Cultured; Chondrocytes; Chondrogenesis; Enzyme Activation; Enzyme Inhibitors; Gene Knockdown Techniques; Humans; I-kappa B Kinase; Imidazoles; Interleukin-1beta; Mesenchymal Stem Cells; NF-kappa B; Niacinamide; Quinoxalines; Resveratrol; Signal Transduction; Sirtuin 1; SOX9 Transcription Factor; Stilbenes

2014
Antitumor activity of a combination of dual PI3K/mTOR inhibitor SAR245409 and selective MEK1/2 inhibitor pimasertib in endometrial carcinomas.
    Gynecologic oncology, 2015, Volume: 138, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Growth Processes; Cell Line, Tumor; Drug Synergism; Endometrial Neoplasms; Female; Humans; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Signaling System; Molecular Targeted Therapy; Niacinamide; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Quinoxalines; Sulfonamides; TOR Serine-Threonine Kinases

2015
Synergistic antitumor effects of combination PI3K/mTOR and MEK inhibition (SAR245409 and pimasertib) in mucinous ovarian carcinoma cells by fluorescence resonance energy transfer imaging.
    Oncotarget, 2016, May-17, Volume: 7, Issue:20

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cystadenocarcinoma, Mucinous; Drug Screening Assays, Antitumor; Drug Synergism; Female; Fluorescence Resonance Energy Transfer; Humans; MAP Kinase Kinase Kinases; Models, Theoretical; Niacinamide; Ovarian Neoplasms; Phosphoinositide-3 Kinase Inhibitors; Quinoxalines; Sulfonamides; TOR Serine-Threonine Kinases

2016
Biomimetic asymmetric reduction of benzoxazinones and quinoxalinones using ureas as transfer catalysts.
    Chemical communications (Cambridge, England), 2020, Jul-07, Volume: 56, Issue:53

    Topics: Benzoxazines; Biomimetic Materials; Catalysis; Cell Cycle Proteins; Coordination Complexes; Hydrogen Bonding; Models, Chemical; Molecular Conformation; NAD; Niacinamide; Oxidation-Reduction; Quinoxalines; Ruthenium; Substrate Specificity; Transcription Factors; Urea

2020