niacinamide and pyrazinamide

niacinamide has been researched along with pyrazinamide in 45 studies

Research

Studies (45)

Timeframe	Studies, this research(%)	All Research%
pre-1990	26 (57.78)	18.7374
1990's	3 (6.67)	18.2507
2000's	4 (8.89)	29.6817
2010's	11 (24.44)	24.3611
2020's	1 (2.22)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Bolívar, BE; Welch, JT	1
Il'ina, TB	1
Eidus, L; Handzel, V; Helbecque, DM	1
Gerloff, W; Kalich, R; Neubert, R; Ulber, H	1
Doi, K	1
Chaplin, DJ; Horsman, MR; Overgaard, J	1
Chaplin, DJ; Horsman, MR; Skov, KA; Trotter, MJ	1
Beurey, J; Cuny, JF; Schmutz, JL; Trechot, P; Weber, M	1
Abeles, RH; Alston, TA	1
Meyer-Rohn, J	1
Feldmann, FM; Konno, K; McDermott, W	1
Tsukamura, M	1
Iwainsky, H; Sehrt, I	1
Brunnemann, H; Tiller, A	1
Deshayes, P; Desseauve, P; Houdent, G; Lemercier, JP; Morere, P; Simonin, JL	1
Rushchak, VA	1
Brander, E	1
Toida, I	2
Altucci, P; Catalano, G; Degen, L; Massarani, E; Nardi, D; Rossi, S; Varone, GL	1
Tatar, J	2
Dulin, WE; Wyse, BM	1
Fox, IH; Gershon, SL	1
Kovalev, GK	1
Berger, NA; Berger, SJ; Catino, DM; Sikorski, GW; Sims, JL	1
Ben-Hur, E; Elkind, MM; Utsumi, H	1
Kroppenstedt, RM; Naumann, L; Reischl, U; Schröder, KH	1
Boshoff, HI; Mizrahi, V	1
An, D; Li, YS; Wang, Y; Wu, J; Zhang, Z	1
McDERMOTT, W; TOMPSETT, R	1
BROUET, G; MARCHE, J	1
Martin, A; Palomino, JC; Portaels, F; Swings, J; Takiff, H; Vandamme, P	1
Cubillos-Ruiz, A; Del Portillo, P; Martin, A; Palomino, JC; Portaels, F; Von Groll, A	1
Echemendía, M; Lemus, D; Madruga, M; Martin, A; Milián, Y; Mirabal, NC; Montoro, E; Palomino, JC; Takiff, H; Van der Stuyf, P; Yzquierdo, SL	1
Bousquet, T; Jakhlal, J; Ladyman, M; Lebibi, J; Maguene, GM; Maugein, J; Pélinski, L; Ralambomanana, DA; Vallin, A	1
García-Carmona, F; García-García, MI; Sánchez-Carrón, G; Sánchez-Ferrer, A; Takami, H; Zapata-Pérez, R	1
Baughn, AD; Dillon, NA; Peterson, ND; Rosen, BC	1
Elamin, AA; Singh, M; Stehr, M	1
Cho, WJ; Choi, YH; Jin, Y; Khadka, DB; Lee, KY; Zhao, C	1
Churakov, AV; Drozd, KV; Manin, AN; Perlovich, GL	1
Fu, Y; Hu, Y; Huang, H; Li, Y; Liang, Q; Luo, J; Ma, Y; Shang, Y; Wu, X; Zhao, L	1
Achanta, PS; Chen, SN; Pauli, GF	1

Reviews

3 review(s) available for niacinamide and pyrazinamide

Article	Year
The use of blood flow modifiers to improve the treatment response of solid tumors. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1991, Volume: 20 Suppl 1 Topics: Animals; Combined Modality Therapy; Hydralazine; Mice; Neoplasms, Experimental; Niacinamide; Pyrazinamide; Regional Blood Flow	1991
[COMPLICATIONS OF A METABOLIC AND ENDOCRINE NATURE PRODUCED BY ANTIBACILLARY CHEMOTHERAPY]. Revue de tuberculose et de pneumologie, 1964, Volume: 28 Topics: Aminosalicylic Acid; Aminosalicylic Acids; Avitaminosis; Cycloserine; Endocrinology; Ethionamide; Isoniazid; Kanamycin; Metabolic Diseases; Niacin; Niacinamide; Pyrazinamide; Streptomycin; Sulfones; Thiosemicarbazones; Toxicology; Viomycin; Vitamin B 6 Deficiency	1964
Pyrazinamide: the importance of uncovering the mechanisms of action in mycobacteria. Expert review of anti-infective therapy, 2015, Volume: 13, Issue:5 Topics: Antitubercular Agents; Humans; Mycobacterium tuberculosis; Niacinamide; Pyrazinamide; Tuberculosis, Pulmonary	2015

Other Studies

42 other study(ies) available for niacinamide and pyrazinamide

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Studies of the Binding of Modest Modulators of the Human Enzyme, Sirtuin 6, by STD NMR. Chembiochem : a European journal of chemical biology, 2017, 05-18, Volume: 18, Issue:10 Topics: Binding Sites; Crystallography, X-Ray; Humans; Kinetics; Magnetic Resonance Imaging; Niacinamide; Protein Binding; Pyrazinamide; Sirtuins; Thermodynamics	2017
[Morphological tinctorial and biochemical properties of Mycobacteria and Nocardia]. Problemy tuberkuleza, 1976, Issue:21 Topics: Acetamides; Amidohydrolases; Formaldehyde; Mycobacterium; Niacinamide; Nocardia; Pyrazinamide; Staining and Labeling; Urea	1976
Simple amidase test for identification of mycobacteria. Journal of clinical microbiology, 1975, Volume: 1, Issue:1 Topics: Acetamides; Allantoin; Amides; Amidohydrolases; Benzamides; Classification; Mycobacterium; Mycobacterium bovis; Mycobacterium tuberculosis; Niacinamide; Pyrazinamide; Urea	1975
[Determination of the sensitivity of mycobacteria to pyrazinamide and nicotinamide (author's transl)]. Zeitschrift fur Erkrankungen der Atmungsorgane, 1978, Volume: 151, Issue:2 Topics: Drug Resistance, Microbial; Humans; Microbial Sensitivity Tests; Mycobacterium; Niacinamide; Pyrazinamide; Tuberculosis, Pulmonary	1978
[Studies on the mechanism of the diabetogenic activity of streptozotocin and on the ability of compounds to block the diabetogenic activity of streptozotocin (author's transl)]. Nihon Naibunpi Gakkai zasshi, 1975, Mar-20, Volume: 51, Issue:3 Topics: Adenoma, Islet Cell; Amides; Animals; Blood Glucose; Cats; Cystine; Deoxyglucose; Diabetes Mellitus; Dimethylnitrosamine; Fatty Acids, Nonesterified; Glutathione; Guinea Pigs; Insulin; Islets of Langerhans; Male; Mannoheptulose; Mice; NAD; Niacinamide; Nicotinic Acids; Pancreatic Neoplasms; Picolinic Acids; Pyrazinamide; Rabbits; Rats; Streptozocin; Tolbutamide; Uric Acid	1975
Modification of tumour radiation response in vivo by the benzamide analogue pyrazinamide. British journal of cancer, 1990, Volume: 62, Issue:4 Topics: Animals; Cell Survival; Cells, Cultured; Hypoxia; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasms, Experimental; Niacinamide; Pyrazinamide; Radiation Tolerance	1990
[Drug-induced pellagroid erythema. A case of pellagroid erythema caused by isoniazide]. Annales de dermatologie et de venereologie, 1987, Volume: 114, Issue:4 Topics: Antineoplastic Agents; Erythema; Ethionamide; Female; Humans; Isoniazid; Middle Aged; Monoamine Oxidase Inhibitors; Niacinamide; Pellagra; Pyrazinamide; Pyridoxine; Skin	1987
Substrate specificity of nicotinamide methyltransferase isolated from porcine liver. Archives of biochemistry and biophysics, 1988, Feb-01, Volume: 260, Issue:2 Topics: Animals; Glycerol; Hydrogen-Ion Concentration; Isoquinolines; Liver; Methyltransferases; Molecular Weight; NAD; Niacinamide; Nicotinamide N-Methyltransferase; Pyrazinamide; Pyridines; Quinolines; Substrate Specificity; Sulfhydryl Compounds; Swine; Tetrahydroisoquinolines	1988
[Comparative research on the differentiation of yeasts using the amide reaction]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1973, Volume: 24, Issue:12 Topics: Acetamides; Allantoin; Amides; Benzamides; Candida; Candida albicans; Colorimetry; Malonates; Niacinamide; Pyrazinamide; Salicylamides; Staining and Labeling; Succinimides; Urea	1973
Pyrazinamide susceptibility and amidase activity of tubercle bacilli. The American review of respiratory disease, 1967, Volume: 95, Issue:3 Topics: Amidohydrolases; Catalase; Drug Resistance, Microbial; Mycobacterium; Mycobacterium bovis; Mycobacterium tuberculosis; Niacinamide; Oxidoreductases; Peroxidases; Pyrazinamide; Urease	1967
Differentiation between Mycobacterium abscessus and Mycobacterium borstelense. The American review of respiratory disease, 1970, Volume: 101, Issue:3 Topics: Alcohols; Amides; Amidohydrolases; Amines; Aminosalicylic Acids; Bacteriological Techniques; Culture Media; Fructose; Glucosamine; Glycols; Humans; Lung Diseases; Malates; Mycobacterium; Niacinamide; Nitrates; Nitrites; Picrates; Pyrazinamide; Salicylates; Succinates; Sulfatases	1970
[Nutritive sources in mycobacteria. 3. The influence of serum on the metabolism of M. smegmatis]. Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. 1. Abt. Medizinisch-hygienische Bakteriologie, Virusforschung und Parasitologie. Originale, 1968, Volume: 207, Issue:4 Topics: Acetates; Amides; Amidohydrolases; Amino Acids; Asparagine; Chromatography, Paper; Colorimetry; Culture Media; Formamides; Glutamine; Glycerol; Isonicotinic Acids; Mycobacterium; Niacinamide; Oxygen Consumption; Propionates; Pyrazinamide; Succinates; Urea	1968
[Determination of acylamidases in enterobacteria]. Archiv fur Hygiene und Bakteriologie, 1970, Volume: 154, Issue:2 Topics: Acetates; Amides; Amidohydrolases; Ammonia; Benzoates; Enterobacteriaceae; Escherichia coli; Malonates; Methods; Niacinamide; Proteus; Pseudomonas aeruginosa; Pyrazinamide; Salicylamides; Salmonella; Shigella; Species Specificity; Urea	1970
[Algodystrophy associated with antitubercular chemotherapy: 22 cases]. Revue du rhumatisme et des maladies osteo-articulaires, 1969, Volume: 36, Issue:6 Topics: Adult; Antitubercular Agents; Cycloserine; Ethambutol; Ethionamide; Female; Humans; Isoniazid; Male; Niacinamide; Pyrazinamide; Reflex Sympathetic Dystrophy; Rifampin; Tuberculosis; Vitamin B Deficiency	1969
[Use of drugs of secondary group in complex therapy of children with chronic tuberculosis]. Pediatriia akusherstvo i ginekologiia, 1971, Volume: 2 Topics: Adolescent; Child; Child, Preschool; Chronic Disease; Cycloserine; Ethionamide; Female; Humans; Male; Niacinamide; Pyrazinamide; Tuberculosis, Pulmonary	1971
A simple way of detecting pyrazinamide resistance. Tubercle, 1972, Volume: 53, Issue:2 Topics: Culture Media; Drug Resistance, Microbial; Hydrogen-Ion Concentration; Methods; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Niacinamide; Pyrazinamide	1972
Pyrazinamide deamidase in tuberculous infection. The American review of respiratory disease, 1973, Volume: 107, Issue:4 Topics: Amidohydrolases; Animals; Antigens; BCG Vaccine; Enzyme Repression; Female; Glycolipids; Liver; Male; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Mycobacterium; Mycobacterium bovis; Mycobacterium Infections; Mycobacterium tuberculosis; Niacinamide; Pyrazinamide; Salmonella; Salmonella enteritidis; Salmonella Infections; Thymectomy; Thymus Gland; Virulence	1973
Antiviral compounds. XV. P-substituted phenylglyoxal-N-acylamido-hemiacetals. Arzneimittel-Forschung, 1973, Volume: 23, Issue:4 Topics: Acetals; Aldehydes; Animals; Antiviral Agents; Chemical Phenomena; Chemistry; Ethers; Glyoxal; Hepatitis Viruses; Mice; Niacinamide; Orthomyxoviridae; Pyrazinamide; Salicylamides; Structure-Activity Relationship; Vaccinia virus	1973
[Sensitivity of tubercle bacilli to pyrazinamide determined on the basis of their sensitivity to nicotinamide and their pyrazinamidase and nictinamidase activities]. Gruzlica i choroby pluc; tuberculosis et pneumonologia, 1974, Volume: 42, Issue:8 Topics: Amidohydrolases; Animals; Cattle; Drug Resistance, Microbial; Humans; Methods; Microbial Sensitivity Tests; Mycobacterium bovis; Mycobacterium tuberculosis; Niacinamide; Pyrazinamide	1974
[Sensitivity of tubercle bacilli to pyrazinamide determined on the basis of their sensitivity to nicotinamide]. Gruzlica i choroby pluc; tuberculosis et pneumonologia, 1974, Volume: 42, Issue:8 Topics: Drug Resistance, Microbial; Hydrogen-Ion Concentration; Methods; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Niacinamide; Pyrazinamide	1974
Studies on the ability of compounds to block the diabetogenic activity of streptozotocin. Diabetes, 1969, Volume: 18, Issue:7 Topics: Amino Acids; Animals; Diabetes Mellitus; Diaphragm; Diazoxide; Epinephrine; Ethanol; Glucosamine; Glucose; Hyperglycemia; Hypoglycemic Agents; Male; NAD; Niacinamide; Nitroso Compounds; Pyrazinamide; Pyrazines; Pyrazoles; Rats; Tolbutamide	1969
Effect of pyrazinamide on nicotinamide adenine dinucleotide glycohydrolase of tuberculous host. The American review of respiratory disease, 1973, Volume: 107, Issue:4 Topics: Animals; Drug Resistance, Microbial; Isoniazid; Liver; Male; Mice; Mycobacterium Infections; Mycobacterium tuberculosis; N-Glycosyl Hydrolases; NAD; Niacinamide; Pyrazinamide	1973
Pharmacologic effects of nicotinic acid on human purine metabolism. The Journal of laboratory and clinical medicine, 1974, Volume: 84, Issue:2 Topics: Adult; Aspirin; Creatinine; Erythrocytes; Female; Gout; Humans; Iopanoic Acid; Kidney Tubules; Male; Middle Aged; Niacinamide; Nicotinic Acids; Organophosphorus Compounds; Pentosephosphates; Pentosyltransferases; Phosphoric Acids; Purines; Pyrazinamide; Pyridines; Sulfinpyrazone; Uric Acid	1974
[Importance of pyrazinamide and beta-pyridinecarboxylic acid amide for differentiating Mycobacteria tuberculosis]. Laboratornoe delo, 1981, Issue:10 Topics: Mycobacterium bovis; Mycobacterium tuberculosis; Niacinamide; Pyrazinamide	1981
Poly(adenosinediphosphoribose) polymerase inhibitors stimulate unscheduled deoxyribonucleic acid synthesis in normal human lymphocytes. Biochemistry, 1982, Apr-13, Volume: 21, Issue:8 Topics: Benzamides; DNA; DNA Repair; Humans; Lymphocytes; Methylnitronitrosoguanidine; NAD; NAD+ Nucleosidase; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Purines; Pyrazinamide	1982
Inhibitors of poly(ADP-ribose) synthesis enhance X-ray killing of log-phase Chinese hamster cells. Radiation research, 1984, Volume: 97, Issue:3 Topics: 4-Aminobenzoic Acid; Animals; Benzamides; Cell Line; Cell Survival; Cricetinae; Cricetulus; Niacinamide; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; ortho-Aminobenzoates; para-Aminobenzoates; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Pyrazinamide; Radiation-Sensitizing Agents	1984
Mycobacterium hassiacum sp. nov., a new rapidly growing thermophilic mycobacterium. International journal of systematic bacteriology, 1997, Volume: 47, Issue:1 Topics: Bacteriological Techniques; Base Composition; Base Sequence; Benzamides; Carbohydrate Metabolism; Citrates; Culture Media; Fatty Acids; Hot Temperature; Iron; Microbial Sensitivity Tests; Molecular Sequence Data; Mycobacterium; Mycolic Acids; Niacinamide; Phylogeny; Polymerase Chain Reaction; Pyrazinamide; Quinones; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Sodium Chloride; Urea	1997
Expression of Mycobacterium smegmatis pyrazinamidase in Mycobacterium tuberculosis confers hypersensitivity to pyrazinamide and related amides. Journal of bacteriology, 2000, Volume: 182, Issue:19 Topics: Amidohydrolases; Antitubercular Agents; Benzamides; Escherichia coli; Gene Expression; Mutagenesis; Mycobacterium smegmatis; Mycobacterium tuberculosis; Niacinamide; Nicotinamidase; Pyrazinamide	2000
Surface-enhanced raman spectra of some anti-tubercle bacillus drugs. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2000, Volume: 56, Issue:14 Topics: Antitubercular Agents; Isoniazid; Niacinamide; Pyrazinamide; Spectrum Analysis, Raman	2000
Activation of pyrazinamide and nicotinamide in acidic environments in vitro. American review of tuberculosis, 1954, Volume: 70, Issue:4 Topics: Environment; In Vitro Techniques; Mycobacterium tuberculosis; Niacin; Niacinamide; Nicotinic Acids; Pyrazinamide	1954
A new rapid and simple colorimetric method to detect pyrazinamide resistance in Mycobacterium tuberculosis using nicotinamide. The Journal of antimicrobial chemotherapy, 2006, Volume: 58, Issue:2 Topics: Amidohydrolases; Antitubercular Agents; Colorimetry; DNA, Bacterial; Drug Resistance, Bacterial; False Positive Reactions; Humans; Indicators and Reagents; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Niacinamide; Oxazines; Oxidation-Reduction; Pyrazinamide; Sensitivity and Specificity; Sequence Analysis, DNA; Xanthenes	2006
Nitrate reductase assay for the rapid detection of pyrazinamide resistance in Mycobacterium tuberculosis using nicotinamide. The Journal of antimicrobial chemotherapy, 2008, Volume: 61, Issue:1 Topics: Antitubercular Agents; Base Sequence; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Genes, Bacterial; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Mycobacterium tuberculosis; Niacinamide; Nitrate Reductase; Pyrazinamide; Time Factors; Tuberculosis, Multidrug-Resistant	2008
Evaluation of colorimetric methods using nicotinamide for rapid detection of pyrazinamide resistance in Mycobacterium tuberculosis. Journal of clinical microbiology, 2010, Volume: 48, Issue:8 Topics: Amidohydrolases; Antitubercular Agents; Colorimetry; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Niacinamide; Nitrates; Organometallic Compounds; Pyrazinamide; Sensitivity and Specificity; Sequence Analysis, DNA	2010
Synthesis and antimycobacterial activity of a series of ferrocenyl derivatives. European journal of medicinal chemistry, 2011, Volume: 46, Issue:1 Topics: Anti-Bacterial Agents; Ferrous Compounds; Metallocenes; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Niacinamide; Pyrazinamide	2011
Biochemical and mutational analysis of a novel nicotinamidase from Oceanobacillus iheyensis HTE831. PloS one, 2013, Volume: 8, Issue:2 Topics: Bacillaceae; Niacinamide; Nicotinamidase; Phylogeny; Pyrazinamide; Substrate Specificity	2013
Pantothenate and pantetheine antagonize the antitubercular activity of pyrazinamide. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:12 Topics: Antitubercular Agents; beta-Alanine; Drug Resistance, Bacterial; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Niacinamide; Pantetheine; Pantothenic Acid; Pyrazinamide	2014
Design and synthesis of novel androgen receptor antagonists via molecular modeling. Bioorganic & medicinal chemistry, 2016, Feb-15, Volume: 24, Issue:4 Topics: Amino Acid Motifs; Androgen Receptor Antagonists; Animals; Antineoplastic Agents; Cell Line; Cell Line, Tumor; Drug Design; Gene Expression; Genes, Reporter; Luciferases; Male; Mice; Molecular Docking Simulation; Molecular Sequence Data; Myoblasts; Niacinamide; Prostate; Protein Structure, Secondary; Pyrazinamide; Pyrimidines; Receptors, Androgen; Receptors, Estrogen; Receptors, Glucocorticoid; Structure-Activity Relationship	2016
Drug-drug cocrystals of antituberculous 4-aminosalicylic acid: Screening, crystal structures, thermochemical and solubility studies. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2017, Mar-01, Volume: 99 Topics: Aminosalicylic Acid; Antitubercular Agents; Caffeine; Crystallization; Crystallography, X-Ray; Drug Stability; Isoniazid; Models, Molecular; Niacinamide; Powder Diffraction; Pyrazinamide; Solubility; Theophylline; X-Ray Diffraction	2017
Detection of pyrazinamide resistance of Mycobacterium tuberculosis using nicotinamide as a surrogate. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2017, Volume: 23, Issue:11 Topics: Antitubercular Agents; DNA, Bacterial; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Niacinamide; Polymerase Chain Reaction; Pyrazinamide; Tuberculosis	2017
Plain Magnetic resonance in chemistry : MRC, 2021, Volume: 59, Issue:7 Topics: Amides; Antiviral Agents; Drug Contamination; Niacinamide; Proton Magnetic Resonance Spectroscopy; Pyrazinamide; Pyrazines; Quality Control; World Health Organization	2021