niacinamide and nitroglycerin

niacinamide has been researched along with nitroglycerin in 110 studies

Research

Studies (110)

Timeframe	Studies, this research(%)	All Research%
pre-1990	45 (40.91)	18.7374
1990's	64 (58.18)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (0.91)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Murao, S; Uchida, Y; Yoshimoto, N	2
Araki, H; Horio, Y; Sakanashi, M; Takenaka, F	1
Imai, S; Katano, Y; Kitagawa, T; Nakagawa, Y; Otorii, T; Takeda, K; Tsukada, T	1
Holzmann, S; Kukovetz, WR; Pöch, G	1
Berdeaux, A; Drieu la Rochelle, C; Giudicelli, JF; Richard, V	1
Bassenge, E; Huckstorf, C	1
Beermann, C; Belz, GG	1
Wagner, G	1
Gross, GJ; Pieper, GM	1
Fukushima, H; Jinno, Y; Kasai, H; Nishikori, K; Ogawa, N; Ohta, H	1
Akima, M; Imagawa, J; Nabata, H; Taira, N	1
Matsuzaki, T; Sakanashi, M	1
McPherson, GA; Stork, AP	1
Cantor, E; Greenberg, SS; Ho, E; Walega, M	1
Borg, C; Cavero, I; Mestre, M; Mondot, S	1
Chiba, S; Horiuchi, A; Iwatsuki, K; Yonekura, H	1
Henry, PJ; Horowitz, JD; Louis, WJ	1
Cipkus-Dubray, LA; Hosner, JM; Khan, SA; Meisheri, KD	1
Satoh, K; Taira, N; Yamada, H	1
Hashimoto, K; Kinoshita, M; Ohbayashi, Y	2
Chibana, T; Mimura, G; Murakami, K; Nagamine, F; Nakada, Y; Oshiro, K; Sakanashi, M; Shimabukuro, M; Shinzato, T; Sunagawa, R	1
Fukuma, N; Hata, N; Hayakawa, H; Kishida, H; Saito, T; Tada, Y; Tetsuoh, Y; Yamazaki, Y; Yasutake, M	1
Hosoda, S; Uchida, T	1
Satoh, K; Taira, N; Yamada, H; Yoneyama, F	1
Satoh, K; Taira, N; Yoneyama, F	1
Karaki, H; Murakami, K; Urakawa, N	1
Imai, S; Katano, Y; Nabata, H; Nakagawa, Y; Nakazawa, M; Takeda, K; Tsukada, T; Ushijima, T	1
Hakuta, T; Kobayashi, K	1
Aizawa, T; Kato, K; Ogasawara, K	1
Kuromaru, O; Sakai, K	4
Holzmann, S; Kukovetz, WR	1
Sugimoto, T; Uchida, Y	1
Domae, M; Hashimoto, T; Kitamura, K; Kuriyama, H; Nakao, K; Sumimoto, K; Yamanaka, K	1
Gross, GJ; Pieper, GM; Warltier, DC	1
Abiko, Y; Ichihara, K; Sakai, K	1
Abe, S; Hattori, S; Kojima, S; Miyamori, R; Miyazaki, T; Mori, H; Nakamura, Y; Sakurai, K; Takahashi, M	1
Ishii, K; Sato, Y; Taira, N	1
Taira, N	1
Kai, H; Kanaide, H; Nakamura, M	1
Brooks, HL; Gross, GJ; Warltier, DC; Wynsen, JC	1
Kukovetz, WR; Romanin, C	1
Fujiwara, M; Muramatsu, I	1
Ogawa, N; Ono, H	1
Ito, H; Kato, T; Nakasone, J; Noguchi, K; Sakanashi, M; Sunagawa, R	1
Araki, H; Hayata, N; Nakamura, M	1
Hader, S; Leitold, M	1
Hattori, S; Kojima, S; Miyamori, R; Miyazaki, T; Mori, H; Nagata, M; Nakamura, Y; Takahashi, M	1
Ohba, Y; Sakai, K; Shiraki, Y	1
Iwaki, M; Kawano, K; Mizobuchi, S; Mori, H; Nakaya, S; Nakaya, Y	1
Ishii, K; Satoh, K; Taira, N; Yanagisawa, T	1
Nakamura, Y; Sakai, K; Sugimoto, T; Yamazaki, T	1
Curzon, G; Green, AR	1
Akima, M; Hinohara, Y; Obatake, N; Sakai, K	1
Itoh, T; Karashima, T; Kuriyama, H	1
Akima, M; Hoshino, E; Sakai, K; Shiraki, Y	1
Imai, S; Nabata, H; Nakazawa, M; Sakai, K; Ushijima, T	1
Nabata, H; Sakai, K	1
Hirakawa, S; Ito, H	1
Nabata, H; Nakamura, Y; Sakai, K; Shiraki, Y	1
Kerfoot, F; Satake, N; Shibata, S; Suh, TK; Takagi, T	1
Inouh, T; Kikuchi, Y; Mizukami, M; Nakamura, M; Tomoike, H; Watanabe, K	1
Inou, T	1
Aono, J; Haruta, K; Sakai, K	1
Kinoshita, M; Nakae, I; Quan, L; Sugimoto, Y; Tsutamoto, T	1
Klein, HH; Lindert-Heimberg, S; Maisch, B; Nebendahl, K; Pich, S; Schade-Brittinger, C	1
Goto, H; Hirata, T; Miyauchi, Y; Obayashi, H; Utoh, J	1
Fukushima, H; Jinno, Y; Kaneta, S; Miwa, A; Ogawa, N	1
Satake, N; Shibata, S; Zhou, Q	1
Fukai, D; Hisanaga, T; Kinoshita, M; Maeda, K; Maeda, Y; Tsutamoto, T; Wada, A; Yoshida, S	1
Bueno, O; Zavecz, JH	1
Gross, GJ; Mizumura, T; Nithipatikom, K	2
Aniya, Y; Naito, A; Sakanashi, M	1
Benedini, F; Bertolini, G; Cereda, R; Donà, G; Gromo, G; Levi, S; Mizrahi, J; Sala, A	1
Berdeaux, A; Dubois-Randé, JL; Ghaleh, B; Giudicelli, JF; Hittinger, L	1
Cavero, I; Durand, I; Magnon, M	1
Bassenge, E; Fink, B; Huckstorf, C; Sommer, O	1
Chujo, M; Mori, H; Nakazawa, H; Okino, H; Tanaka, E	1
Ando, S; Endo, T; Imaizumi, T; Kubo, T; Shiramoto, M; Tagawa, T; Takeshita, A; Tokunaga, S	1
Fukasawa, M; Fukui, K; Hirooka, S; Kohi, M; Orita, H; Uchino, H; Washio, M	1
Billon, N; Funck-Brentano, C; Jaillon, P; Tabone, X	1
Akamatsu, S; Dohi, S; Iida, H; Ishiyama, T; Ohta, S; Shimonaka, H	1
Fukasawa, M; Fukui, K; Hirooka, S; Kohi, M; Orita, H; Washio, M	1
Hashimoto, K; Kinoshita, M; Nakae, I; Quan, L; Sugimoto, Y; Tsutamoto, T	1
Abe, S; Kanaide, H; Nakamura, M; Nishimura, J	1
Horie, H; Kinoshita, M; Maeda, Y; Nakae, I; Tsutamoto, T; Wada, A; Yabe, T	1
Iimura, O; Itoya, M; Iwamoto, T; Miura, T; Shimamoto, K; Urabe, K	1
Fukushima, H; Jinno, Y; Kaneta, S; Kasai, H; Miwa, A; Motoki, K; Ogawa, N; Okada, Y	1
Kato, K	1
Kato, H; Kurihara, J; Ochiai, N	1
Bokor, D; Carotenuto, A; de Divitiis, M; de Divitiis, O; Di Somma, S; Liguori, V; Petitto, M	1
Campa, PP; Dawodu, AA; del Monte, F; Marino, B; Monti, F; Puddu, PE; Schiariti, M; Sugimoto, S	1
Humphrey, SJ; Schwende, FJ	1
Advenier, C; Dumas, JP; Dumas, M; Giudicelli, JF; Rochette, L	1
O'Rourke, ST	1
Bergamaschi, M; Gromo, G; Mizrahi, J; Nonaka, K; Ueno, A	1
Aisaka, K; Hirata, Y	1
Murayama, S; Nakano, T; Yamakado, T	1
Kinoshita, M; Liu, Q; Matsumoto, T; Nakae, I; Omura, T; Takahashi, M; Takaoka, A	1
Aarsland, T; Dickstein, K; Gøransson, L; Larsen, AI; Tamby, JF	1
Araki, H; Higuchi, S; Noguchi, K; Takahashi, K	1
Igata, Y; Ikeda, S; Maekawa, T; Shiraishi, M; Watanabe, T; Yamamoto, S	1
Koyama, T; Matsuzaki, T; Nakasone, J; Noguchi, K; Ojiri, Y; Sakanashi, M	1
Kanki, H; Nishikawa, Y; Ogawa, S	1

Reviews

4 review(s) available for niacinamide and nitroglycerin

Article	Year
Actions of nicorandil on vascular smooth muscles. Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 8 Topics: Action Potentials; Animals; Calcium; Cyclic GMP; In Vitro Techniques; Ion Channels; Membrane Potentials; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Vasoconstriction; Vasodilator Agents	1987
Nicorandil as a hybrid between nitrates and potassium channel activators. The American journal of cardiology, 1989, Jun-20, Volume: 63, Issue:21 Topics: Animals; Dogs; Niacinamide; Nicorandil; Nitroglycerin; Potassium Channels; Stimulation, Chemical; Vasodilator Agents	1989
Pharmacologic therapy of angina pectoris. The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society, 1995, Volume: 147, Issue:5 Topics: Acetanilides; Adrenergic beta-Antagonists; Angina Pectoris; Aspirin; Calcium Channel Blockers; Drug Therapy, Combination; Enoximone; Heparin; Humans; Isosorbide Dinitrate; Niacinamide; Nicorandil; Nitroglycerin; Piperazines; Ranolazine; Vasodilator Agents	1995
Haemodynamic and clinical effects of an intravenous potassium channel opener--a review. European heart journal, 1993, Volume: 14 Suppl B Topics: Administration, Sublingual; Angina, Unstable; Coronary Circulation; Coronary Disease; Hemodynamics; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Niacinamide; Nicorandil; Nitroglycerin; Potassium Channels; Vasodilator Agents	1993

Trials

11 trial(s) available for niacinamide and nitroglycerin

Article	Year
Selected issues from an overview on nicorandil: tolerance, duration of action, and long-term efficacy. Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 3 Topics: Administration, Oral; Administration, Sublingual; Angina Pectoris; Drug Administration Schedule; Drug Tolerance; Exercise; Female; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Niacinamide; Nicorandil; Nitroglycerin	1992
Comparison of the acute hemodynamic and coronary vasodilating effects between nicorandil and glyceryl trinitrate. Arzneimittel-Forschung, 1991, Volume: 41, Issue:6 Topics: Adult; Blood Pressure; Cardiac Output; Coronary Circulation; Female; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Niacinamide; Nicorandil; Nitroglycerin; Pulmonary Circulation; Stroke Volume; Vascular Resistance; Vasodilation; Vasodilator Agents	1991
Effects of nicorandil on exercise tolerance in patients with stable effort angina: a double-blind study. American heart journal, 1986, Volume: 112, Issue:6 Topics: Aged; Angina Pectoris; Clinical Trials as Topic; Double-Blind Method; Exercise Test; Female; Hemodynamics; Humans; Male; Middle Aged; Niacinamide; Nicorandil; Nitroglycerin; Physical Endurance; Physical Exertion; Placebos; Time Factors; Vasodilator Agents	1986
Hemodynamic effects of bolus nicorandil compared with nitroglycerin. The American journal of emergency medicine, 1995, Volume: 13, Issue:5 Topics: Aged; Cardiovascular Diseases; Emergencies; Female; Hemodynamics; Humans; Male; Middle Aged; Niacinamide; Nicorandil; Nitroglycerin; Vasodilator Agents	1995
Comparison of hemodynamic effects and plasma cyclic guanosine monophosphate of nicorandil and nitroglycerin in patients with congestive heart failure. The American journal of cardiology, 1995, Jun-01, Volume: 75, Issue:16 Topics: Adult; Aged; Analysis of Variance; Blood Pressure; Cyclic GMP; Female; Heart Failure; Hemodynamics; Humans; Least-Squares Analysis; Male; Middle Aged; Niacinamide; Nicorandil; Nitroglycerin; Pulmonary Wedge Pressure; Regression Analysis; Vasodilator Agents	1995
Comparison of tolerance to intravenous nitroglycerin during nicorandil and intermittent nitroglycerin patch in healthy volunteers. Clinical pharmacology and therapeutics, 1994, Volume: 56, Issue:6 Pt 1 Topics: Administration, Cutaneous; Adult; Analysis of Variance; Drug Administration Schedule; Drug Tolerance; Hemodynamics; Humans; Injections, Intravenous; Male; Niacinamide; Nicorandil; Nitroglycerin; Reference Values; Vasodilator Agents	1994
Absence of hemodynamic tolerance to nicorandil in patients with severe congestive heart failure. American heart journal, 1994, Volume: 127, Issue:4 Pt 1 Topics: Adult; Aged; Atrial Natriuretic Factor; Drug Tolerance; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Niacinamide; Nicorandil; Nitroglycerin; Pulmonary Wedge Pressure; Vasodilator Agents	1994
A double-blind comparison of nicorandil and metoprolol in stable effort angina pectoris. Cardiovascular drugs and therapy, 1993, Volume: 7, Issue:1 Topics: Adult; Angina Pectoris; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Exercise Test; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Niacinamide; Nicorandil; Nitroglycerin; Vasodilator Agents	1993
Effects of nicorandil, an antianginal potassium channel opener, on left ventricular systolic and diastolic function in patients with chronic coronary artery disease. The American journal of cardiology, 1997, Jun-15, Volume: 79, Issue:12 Topics: Adult; Aged; Chronic Disease; Coronary Disease; Diastole; Female; Humans; Male; Middle Aged; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Potassium Channels; Systole; Vasodilator Agents; Ventricular Function, Left; Ventricular Pressure	1997
Comparison of the degree of hemodynamic tolerance during intravenous infusion of nitroglycerin versus nicorandil in patients with congestive heart failure. American heart journal, 1997, Volume: 134, Issue:3 Topics: Aged; Cross-Over Studies; Double-Blind Method; Female; Heart Failure; Hemodynamics; Humans; Infusions, Intravenous; Male; Middle Aged; Niacinamide; Nicorandil; Nitroglycerin; Treatment Outcome; Vasodilator Agents	1997
Differential effects of N-acetylcysteine on nitroglycerin- and nicorandil-induced vasodilation in human coronary circulation. Journal of cardiovascular pharmacology, 1998, Volume: 32, Issue:1 Topics: Acetylcysteine; Coronary Circulation; Coronary Disease; Coronary Vessels; Female; Free Radical Scavengers; Hemodynamics; Humans; Male; Middle Aged; Niacinamide; Nicorandil; Nitroglycerin; Vasodilation; Vasodilator Agents	1998

Other Studies

95 other study(ies) available for niacinamide and nitroglycerin

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Effects of anti-anginal agents on cyclical reductions of coronary blood flow. Japanese heart journal, 1978, Volume: 19, Issue:6 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Blood Pressure; Coronary Circulation; Diltiazem; Dipyridamole; Dogs; Electrocardiography; Injections, Intravenous; Niacinamide; Nicotinic Acids; Nifedipine; Nitrates; Nitroglycerin; Papaverine; Periodicity; Phentolamine; Propranolol; Vasodilator Agents; Verapamil	1978
Effect of 2-nicotinamidethyl nitrate (SG 75) on coronary circulation. Japanese heart journal, 1978, Volume: 19, Issue:1 Topics: Animals; Constriction, Pathologic; Coronary Circulation; Coronary Vessels; Diltiazem; Dogs; Heart Rate; Isosorbide Dinitrate; Ligation; Niacinamide; Nifedipine; Nitrates; Nitroglycerin; Papaverine; Vasodilator Agents; Verapamil	1978
Effects of 2-nicotinamidoethyl nitrate (SG-75) on dog coronary artery and cat papillary muscle. Japanese heart journal, 1979, Volume: 20, Issue:4 Topics: Animals; Calcium Chloride; Cats; Coronary Vessels; Dogs; Electric Stimulation; Female; Isoproterenol; Male; Muscle Contraction; Niacinamide; Nitrates; Nitroglycerin; Papillary Muscles	1979
Effects of 2-nicotinamidoethyl nitrate on the cardiovascular system. Japanese heart journal, 1979, Volume: 20, Issue:6 Topics: Animals; Blood Pressure; Cardiovascular System; Cerebrovascular Circulation; Coronary Circulation; Coronary Vessels; Dogs; Energy Metabolism; Female; Heart; Heart Rate; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Myocardium; Niacinamide; Nitrates; Nitroglycerin; Vasodilator Agents; Veins	1979
Molecular mechanism of action of nicorandil. Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 3 Topics: Animals; Benzopyrans; Cattle; Coronary Vessels; Cromakalim; Cyclic GMP; Dose-Response Relationship, Drug; In Vitro Techniques; Niacinamide; Nicorandil; Nitroglycerin; Nitroprusside; Pyrroles; Vasodilation; Vasodilator Agents	1992
Differential effects of nitrovasodilators, K(+)-channel openers, and nicorandil on large and small coronary arteries in conscious dogs. Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 3 Topics: Animals; Benzopyrans; Coronary Vessels; Cromakalim; Dogs; Dose-Response Relationship, Drug; Injections, Intravenous; Molsidomine; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Potassium Channels; Pyrroles; Vasodilation; Vasodilator Agents	1992
Effects of long-term nicorandil application on coronary arteries in conscious dogs. Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 3 Topics: Animals; Blood Pressure; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; Female; Heart Rate; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Niacinamide; Nicorandil; Nitroglycerin; Vasodilation	1992
Venodilatory effects of nicorandil in healthy volunteers. Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 3 Topics: Administration, Oral; Administration, Sublingual; Hand; Humans; Niacinamide; Nicorandil; Nitroglycerin; Vasodilation; Vasodilator Agents; Veins	1992
Anti-free-radical and neutrophil-modulating properties of the nitrovasodilator, nicorandil. Cardiovascular drugs and therapy, 1992, Volume: 6, Issue:3 Topics: Animals; Dogs; Dose-Response Relationship, Drug; Free Radical Scavengers; Free Radicals; Glyburide; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Neutrophils; Niacinamide; Nicorandil; Nitroglycerin; Opsonin Proteins; Superoxides; Tetradecanoylphorbol Acetate; Vasodilator Agents	1992
Contribution of cyclic GMP formation to KRN2391-induced relaxation in coronary artery of the pig. British journal of pharmacology, 1992, Volume: 106, Issue:4 Topics: Animals; Coronary Vessels; Cyclic GMP; Dose-Response Relationship, Drug; In Vitro Techniques; Niacinamide; Nicorandil; Nitroglycerin; Pyridines; Swine; Vasodilation; Vasodilator Agents	1992
Spasmolytic action of nicorandil in canine conductive coronary arteries in vivo is not modified by glibenclamide. Journal of cardiovascular pharmacology, 1992, Volume: 19, Issue:1 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiocardiography; Animals; Benzopyrans; Coronary Circulation; Coronary Vasospasm; Coronary Vessels; Cromakalim; Dogs; Female; Glyburide; Male; Niacinamide; Nicorandil; Nitroglycerin; Parasympatholytics; Potassium Channels; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Vasodilator Agents	1992
Comparison of the development of tolerance to nitroglycerin in aortic preparations isolated from non-diabetic and diabetic rats. Heart and vessels, 1992, Volume: 7, Issue:1 Topics: Acetylcysteine; Animals; Aorta, Thoracic; Blood Glucose; Culture Techniques; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Dose-Response Relationship, Drug; Drug Tolerance; Glycated Hemoglobin; Male; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Norepinephrine; Rats; Rats, Inbred Strains; Vasodilation; Vasodilator Agents	1992
The resistance of some rat cerebral arteries to the vasorelaxant effect of cromakalim and other K+ channel openers. British journal of pharmacology, 1992, Volume: 105, Issue:1 Topics: Acetylcholine; Animals; Antihypertensive Agents; Benzopyrans; Cerebellum; Cerebral Arteries; Cromakalim; Guanidines; Guinea Pigs; Niacinamide; Nicorandil; Nitric Oxide; Nitroglycerin; Pinacidil; Potassium Channels; Pyrroles; Rabbits; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance; Vasodilator Agents	1992
Comparison of nicorandil-induced relaxation, elevations of cyclic guanosine monophosphate and stimulation of guanylate cyclase with organic nitrate esters. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 258, Issue:3 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Cyclic GMP; Dogs; Endothelium, Vascular; Enzyme Activation; Esters; Female; Guanylate Cyclase; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitrates; Nitric Oxide; Nitroglycerin; Stimulation, Chemical; Vasodilator Agents	1991
Nicorandil: differential contribution of K+ channel opening and guanylate cyclase stimulation to its vasorelaxant effects on various endothelin-1-contracted arterial preparations. Comparison to aprikalim (RP 52891) and nitroglycerin. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:2 Topics: Animals; Coronary Vessels; Endothelins; Endothelium, Vascular; Glyburide; Guanylate Cyclase; Heart; Hemodynamics; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Picolines; Potassium Channels; Purinones; Pyrans; Rats; Rats, Inbred Strains; Stimulation, Chemical; Swine; Swine, Miniature; Vasodilator Agents	1991
Effects of N-(2-hydroxyethyl)nicotinamide nitrate (nicorandil; SG-75) and its derivatives on pancreatic exocrine secretion in the dog. Pancreas, 1990, Volume: 5, Issue:1 Topics: Amylases; Animals; Bicarbonates; Dogs; Female; Guanidines; Male; Niacinamide; Nicorandil; Nitroglycerin; Pancreatic Juice; Pinacidil; Secretory Rate; Structure-Activity Relationship; Tetraethylammonium Compounds	1990
Nitrate tolerance induced by nicorandil or nitroglycerin is associated with minimal loss of nicorandil vasodilator activity. Journal of cardiovascular pharmacology, 1990, Volume: 15, Issue:3 Topics: Animals; Arteries; Cattle; Coronary Vessels; Drug Tolerance; In Vitro Techniques; Isosorbide Dinitrate; Molsidomine; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitrates; Nitric Oxide; Nitroglycerin; Vasodilator Agents	1990
Nicorandil-induced vasorelaxation: functional evidence for K+ channel-dependent and cyclic GMP-dependent components in a single vascular preparation. Journal of cardiovascular pharmacology, 1991, Volume: 17, Issue:6 Topics: Animals; Calcium; Cyclic GMP; Drug Tolerance; Mesenteric Arteries; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Norepinephrine; Potassium; Potassium Channels; Rabbits; Vasodilator Agents	1991
Differential antagonism by glibenclamide of the relaxant effects of cromakalim, pinacidil and nicorandil on canine large coronary arteries. Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 343, Issue:1 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arteries; Benzopyrans; Coronary Vessels; Cromakalim; Dogs; Dose-Response Relationship, Drug; Female; Glyburide; Guanidines; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Pinacidil; Potassium; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Vasodilator Agents	1991
Coronary effects of nicorandil in comparison with nitroglycerin in chronic conscious dogs. Cardiovascular drugs and therapy, 1991, Volume: 5, Issue:1 Topics: Animals; Blood Pressure; Coronary Vessels; Dogs; Female; Heart Rate; Male; Niacinamide; Nicorandil; Nitroglycerin; Vasodilator Agents	1991
A new strategy for the reduction of acute myocardial infarction in variant angina. American heart journal, 1991, Volume: 122, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris, Variant; Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Coronary Angiography; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Humans; Male; Middle Aged; Myocardial Infarction; Niacinamide; Nicorandil; Nitroglycerin; Regression Analysis; Retrospective Studies; Vasodilator Agents	1991
[Drug therapy of unstable angina]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1990, Nov-10, Volume: 79, Issue:11 Topics: Adrenergic beta-Antagonists; Angina, Unstable; Aspirin; Calcium Channel Blockers; Drug Therapy, Combination; Heparin; Humans; Niacinamide; Nicorandil; Nitroglycerin	1990
Specific but differential antagonism by glibenclamide of the vasodepressor effects of cromakalim and nicorandil in spinally-anaesthetized dogs. British journal of pharmacology, 1990, Volume: 100, Issue:3 Topics: Anesthesia, Spinal; Animals; Benzopyrans; Blood Pressure; Calcium Channel Blockers; Cromakalim; Diltiazem; Dogs; Dose-Response Relationship, Drug; Female; Glyburide; Heart Rate; Hemodynamics; Male; Myocardial Contraction; Niacinamide; Nicorandil; Nitroglycerin; Norepinephrine; Potassium Channels; Pyrroles	1990
Left ventricular effects of nicorandil in comparison with nitroglycerin in chronic conscious dogs. Cardiovascular drugs and therapy, 1990, Volume: 4, Issue:6 Topics: Animals; Dogs; Heart Ventricles; Hemodynamics; Injections, Intravenous; Niacinamide; Nicorandil; Nitroglycerin; Vasodilator Agents	1990
Nicorandil increases coronary blood flow predominantly by K-channel opening mechanism. Cardiovascular drugs and therapy, 1990, Volume: 4, Issue:4 Topics: Adenosine Triphosphate; Animals; Benzopyrans; Coronary Circulation; Cromakalim; Dogs; Dose-Response Relationship, Drug; Female; Glyburide; In Vitro Techniques; Male; Myocardial Contraction; Niacinamide; Nicorandil; Nitroglycerin; Potassium Channels; Pyrroles; Vasodilator Agents	1990
Comparison of the inhibitory effects of nicorandil, nitroglycerin and isosorbide dinitrate on vascular smooth muscle of rabbit aorta. European journal of pharmacology, 1987, Sep-11, Volume: 141, Issue:2 Topics: Animals; Aorta; Calcium; Cyclic GMP; In Vitro Techniques; Ion Channels; Isosorbide Dinitrate; Male; Muscle Contraction; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Norepinephrine; Rabbits	1987
Effects of nicorandil on the conductive coronary artery of the dog. Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 8 Topics: Animals; Coronary Vessels; Dogs; Female; In Vitro Techniques; Lanthanum; Male; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Perfusion; Potassium; Vasoconstriction; Vasodilator Agents	1987
Effects of nicorandil on coronary hemodynamics in ischemic heart disease: comparison with nitroglycerin, nifedipine, and propranolol. Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 8 Topics: Adult; Aged; Cardiac Pacing, Artificial; Coronary Circulation; Coronary Disease; Hemodynamics; Humans; Lactates; Lactic Acid; Middle Aged; Myocardium; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Norepinephrine; Oxygen Consumption; Propranolol; Vasodilator Agents	1987
Effects of nicorandil on coronary circulation in patients with ischemic heart disease: comparison with nitroglycerin. Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 8 Topics: Coronary Circulation; Coronary Disease; Coronary Vasospasm; Female; Hemodynamics; Humans; Male; Middle Aged; Niacinamide; Nicorandil; Nitroglycerin; Vasodilation; Vasodilator Agents	1987
Nitrate tolerance: comparison of nicorandil, isosorbide dinitrate, and nitroglycerin in anesthetized dogs. Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 8 Topics: Anesthesia; Animals; Coronary Circulation; Dogs; Drug Tolerance; Female; Infusions, Intravenous; Injections, Intra-Arterial; Isosorbide Dinitrate; Male; Niacinamide; Nicorandil; Nitroglycerin; Vasodilator Agents	1987
Cyclic GMP in nicorandil-induced vasodilatation and tolerance development. Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 8 Topics: Acetylcysteine; Animals; Cattle; Coronary Vessels; Cyclic GMP; Drug Tolerance; In Vitro Techniques; Isosorbide Dinitrate; Niacinamide; Nicorandil; Nitroglycerin; Vasodilation; Vasodilator Agents	1987
The effects of nicorandil on phasic contractions of isolated canine coronary artery. Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 8 Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Calmodulin; Coronary Vessels; Dogs; Ergonovine; In Vitro Techniques; Membrane Potentials; Muscle Contraction; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Vasodilator Agents	1987
Comparative effects of nicorandil, nitroglycerin, nicotinic acid, and SG-86 on the metabolic status and functional recovery of the ischemic-reperfused myocardium. Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 8 Topics: Animals; Coronary Circulation; Coronary Disease; Dogs; Fatty Acids, Nonesterified; Female; Glucose; Heart; Hemodynamics; Male; Myocardial Contraction; Myocardium; Niacin; Niacinamide; Nicorandil; Nitroglycerin; Perfusion; Vasodilator Agents	1987
Effects of nicorandil and other antianginal drugs on myocardial pH in the ischemic dog heart. Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 8 Topics: Acidosis; Animals; Coronary Disease; Diltiazem; Dogs; Hydrogen-Ion Concentration; In Vitro Techniques; Myocardium; Niacinamide; Nicorandil; Nitroglycerin; Propranolol; Sotalol; Vasodilator Agents	1987
Examination of the direct effects of nicorandil, verapamil, propranolol, and nitroglycerin on the hypoxic canine myocardium. Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 8 Topics: Animals; Coronary Disease; Dogs; Female; Hemodynamics; In Vitro Techniques; Male; Myocardium; Niacinamide; Nicorandil; Nitroglycerin; Perfusion; Propranolol; Vasodilator Agents; Verapamil	1987
Differential antagonism by Bay K 8644 of vasodilator effects of nifedipine, diltiazem, nicorandil and nitroglycerin in dog femoral circulation. British journal of pharmacology, 1988, Volume: 93, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Diltiazem; Dogs; Dose-Response Relationship, Drug; Female; Femoral Artery; Femur; Male; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Regional Blood Flow; Vasodilator Agents	1988
Effects of nicorandil on cytosolic calcium concentrations in quin2-loaded rat aortic vascular smooth muscle cells in primary culture. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:3 Topics: Aminoquinolines; Animals; Aorta; Caffeine; Calcium; Cells, Cultured; Cyclic GMP; Cytosol; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Norepinephrine; Potassium; Rats; Rats, Inbred Strains; Vasodilator Agents	1989
Differential effects of nifedipine, nicorandil and nitroglycerin on the pressor responses elicited by selective alpha-1 and alpha-adrenoceptor agonists in conscious dogs. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:3 Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Dogs; Female; Hemodynamics; Male; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Phenylephrine; Vasodilator Agents	1987
Guanylate cyclase activation by organic nitrates is not mediated via nitrite. Journal of molecular and cellular cardiology, 1988, Volume: 20, Issue:5 Topics: Enzyme Activation; Guanylate Cyclase; Isosorbide Dinitrate; Kinetics; Niacinamide; Nicorandil; Nitrates; Nitrites; Nitroglycerin; Sulfhydryl Compounds; Vasodilator Agents	1988
[Vasorelaxing action of nicorandil, in comparison with nitroglycerin and Ca antagonists]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1986, Volume: 87, Issue:2 Topics: Animals; Aorta; Aorta, Thoracic; Calcium Channel Blockers; Diltiazem; Drug Interactions; Male; Niacinamide; Nicorandil; Nitroglycerin; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Vasodilator Agents; Verapamil	1986
Different effects of various vasodilators on autoregulation of renal blood flow in anesthetized dogs. Japanese journal of pharmacology, 1986, Volume: 41, Issue:3 Topics: Animals; Blood Pressure; Diltiazem; Dogs; Female; Homeostasis; Male; Niacinamide; Nicorandil; Nitroglycerin; Nitroprusside; Papaverine; Renal Circulation; Sodium Nitrite; Vasodilator Agents	1986
Vasodilating effects of nicorandil and nitroglycerin in anaesthetized open-chest dogs. Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 333, Issue:4 Topics: Anesthesia; Animals; Coronary Circulation; Dogs; Female; Male; Niacinamide; Nicorandil; Nitroglycerin; Renal Circulation; Vascular Resistance; Vasodilator Agents	1986
Effects of nicorandil on the rhythmic contractile response of isolated miniature pig coronary artery to 3,4-diaminopyridine: comparison with nitroglycerin. Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 283, Issue:2 Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Coronary Vasospasm; Coronary Vessels; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Swine; Swine, Miniature	1986
Cardiovascular effects of isosorbide dinitrate infused intravenously into anaesthetized dogs. Clinical and experimental pharmacology & physiology, 1986, Volume: 13, Issue:8 Topics: Animals; Blood Pressure; Coronary Circulation; Dogs; Female; Hemodynamics; Infusions, Intravenous; Isosorbide Dinitrate; Male; Niacinamide; Nicorandil; Nitroglycerin; Stroke Volume	1986
Comparison of development of tolerance between nicorandil and nitroglycerin in anesthetized, open-chest dogs. Japanese journal of pharmacology, 1986, Volume: 42, Issue:2 Topics: Animals; Coronary Circulation; Coronary Vessels; Dogs; Drug Interactions; Drug Tolerance; Female; Hemodynamics; Infusions, Intravenous; Injections, Intra-Arterial; Male; Niacinamide; Nicorandil; Nitroglycerin; Vasodilator Agents	1986
[Influence of antianginal drugs on Lypressin induced T-wave enhancement in the electrocardiogram of the rat]. Arzneimittel-Forschung, 1986, Volume: 36, Issue:10 Topics: Administration, Oral; Angina Pectoris; Animals; Coronary Vasospasm; Electrocardiography; Hypoxia; Isosorbide Dinitrate; Lypressin; Male; Molsidomine; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Rats; Rats, Inbred Strains; Verapamil	1986
Examination of the direct effects of antianginal agents on the hypoxic canine myocardium. Japanese heart journal, 1987, Volume: 28, Issue:5 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cardiomyopathies; Coronary Circulation; Dogs; Female; Hypoxia; Male; Myocardial Contraction; Myocardium; Niacinamide; Nicorandil; Nitroglycerin; Vasodilator Agents	1987
Comparative vasorelaxing profiles of nicorandil, isosorbide dinitrate and nitroglycerin in isolated coronary arteries of the dog. Japanese journal of pharmacology, 1987, Volume: 45, Issue:3 Topics: Acetylcysteine; Animals; Coronary Vessels; Dinoprost; Dogs; Endothelium; Female; In Vitro Techniques; Isosorbide Dinitrate; Male; Methylene Blue; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Potassium Chloride; Prostaglandins F; Vasodilator Agents	1987
Tetraethylammonium-induced contraction of rabbit coronary artery. Heart and vessels, 1988, Volume: 4, Issue:3 Topics: Animals; Arteries; Coronary Vessels; Ergonovine; Isoproterenol; Muscle Contraction; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Rabbits; Tetraethylammonium Compounds; Vasoconstriction	1988
Abolition of spontaneous rhythmic contractions of isolated monkey coronary arteries by diltiazem, nifedipine, verapamil and nicorandil but not by nitroglycerin. The Tohoku journal of experimental medicine, 1985, Volume: 145, Issue:1 Topics: Animals; Calcium Channel Blockers; Coronary Vessels; Diltiazem; Erythrocebus patas; Female; In Vitro Techniques; Macaca mulatta; Male; Muscle Contraction; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Verapamil	1985
Protective effects of the antianginal agent nicorandil on arachidonate-induced sudden death in rats: comparison with several antianginal agents and cyclooxygenase inhibitors. Japanese journal of pharmacology, 1985, Volume: 37, Issue:1 Topics: Angina Pectoris; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Death, Sudden; Diltiazem; Indomethacin; Male; Mice; Niacinamide; Nicorandil; Nitroglycerin; Rats; Rats, Inbred Strains; Vasodilator Agents	1985
The effect of tryptophan metabolites on brain 5-hydroxytryptamine metabolism. Biochemical pharmacology, 1970, Volume: 19, Issue:6 Topics: Alanine; Allopurinol; Amino Acids; Animals; Brain; Brain Chemistry; Carbon Isotopes; Carboxy-Lyases; Histamine; Kynurenic Acid; Kynurenine; Male; Methanol; Methyldopa; Mixed Function Oxygenases; Niacinamide; Nicotinic Acids; Nitroglycerin; ortho-Aminobenzoates; Phenylalanine; Phenylbutyrates; Picolinic Acids; Pyridines; Pyridoxal Phosphate; Pyridoxine; Rats; Serotonin; Sulfuric Acids; Time Factors; Tryptophan; Tryptophan Oxygenase; Xanthurenates	1970
Hypotensive effects and biotransformation of nicorandil, a new antianginal agent, administered to rats by different routes: comparison with nitroglycerin and isosorbide dinitrate. The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:3 Topics: Animals; Antihypertensive Agents; Biotransformation; Blood Pressure; Dogs; Guinea Pigs; In Vitro Techniques; Isosorbide Dinitrate; Liver; Macaca mulatta; Male; Niacinamide; Nicorandil; Nitroglycerin; Rats; Rats, Inbred Strains; Swine; Vasodilator Agents	1984
Effects of 2-nicotinamidoethyl nitrate on smooth muscle cells of the guinea-pig mesenteric and portal veins. The Journal of pharmacology and experimental therapeutics, 1982, Volume: 221, Issue:2 Topics: Acetylcholine; Animals; Female; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Membranes; Mesenteric Veins; Muscle Contraction; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitrates; Nitroglycerin; Norepinephrine; Portal Vein; Vasodilator Agents	1982
Effects of a new antianginal agent, nicorandil, on the cardiovascular system of the miniature pig: with special reference to coronary vasospasm. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:1 Topics: Animals; Blood Pressure; Cardiovascular System; Coronary Circulation; Coronary Vasospasm; Dipyridamole; Female; Male; Myocardium; Niacinamide; Nicorandil; Nitroglycerin; Oxygen Consumption; Swine; Swine, Miniature; Vascular Resistance; Vasomotor System	1983
Mechanism of relaxant effects of nicorandil on the dog coronary artery. Archives internationales de pharmacodynamie et de therapie, 1983, Volume: 265, Issue:2 Topics: Animals; Caffeine; Calcium; Coronary Vessels; Dogs; Female; Lanthanum; Male; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Potassium; Vasoconstriction; Vasodilation; Vasodilator Agents	1983
Effects of a new antianginal agent, nicorandil, on normoxic and anoxic contractions in isolated miniature pig coronary arteries exposed to 5-hydroxytryptamine and norepinephrine: comparison with nitroglycerin and diltiazem. European journal of pharmacology, 1983, Dec-09, Volume: 96, Issue:1-2 Topics: Animals; Benzazepines; Coronary Vessels; Diltiazem; Drug Interactions; Female; Male; Muscle Contraction; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Norepinephrine; Oxygen; Serotonin Antagonists; Swine; Swine, Miniature	1983
Effects of vasodilators on the systemic capacitance vessels, a study with the measurement of the mean circulatory pressure in dogs. Japanese circulation journal, 1984, Volume: 48, Issue:4 Topics: Animals; Blood Pressure; Blood Vessels; Blood Volume; Cardiac Output; Diltiazem; Dogs; Heart Rate; Isosorbide Dinitrate; Molsidomine; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Prazosin; Sydnones; Trapidil; Vascular Resistance; Vasodilator Agents; Venous Pressure; Verapamil	1984
Comparative effects of nicorandil and nitroglycerin on tracheal and vascular smooth muscle in the dog, in vivo and in vitro. Japanese journal of pharmacology, 1984, Volume: 34, Issue:3 Topics: Animals; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Female; Hemodynamics; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Potassium Chloride; Regional Blood Flow; Trachea; Vasodilator Agents	1984
Relaxing effect of nicorandil (N-2-(hydroxyethyl)-nicotinamide nitrate), a new anti-angina agent, on the isolated vascular smooth muscle. European journal of pharmacology, 1984, Mar-23, Volume: 99, Issue:2-3 Topics: Animals; Aorta, Thoracic; Basilar Artery; Calcium; Cats; Coronary Vessels; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Norepinephrine; Potassium Chloride; Rabbits; Vasodilator Agents	1984
Effects of 2-nicotinamidethyl nitrate (SG-75) and/or nitroglycerin on systemic hemodynamics and coronary blood flow in conscious dogs. Arzneimittel-Forschung, 1981, Volume: 31, Issue:8 Topics: Animals; Blood Pressure; Coronary Circulation; Dogs; Heart Rate; Hemodynamics; Niacinamide; Nicorandil; Nitrates; Nitroglycerin; Vascular Resistance; Vasodilator Agents	1981
[Studies on the relation between collateral development and the effects of antianginal drugs--effects of nitroglycerin and 2-nicotinamidethyl nitrate on collateral circulation (author's transl)]. Fukuoka igaku zasshi = Hukuoka acta medica, 1981, Volume: 72, Issue:8 Topics: Angina Pectoris; Animals; Collateral Circulation; Coronary Circulation; Dogs; Niacinamide; Nicorandil; Nitrates; Nitroglycerin	1981
Effects of a new coronary vasodilator, N-(2-hydroxyethyl)nicotinamide nitrate (SG-75) and nitroglycerin on cardiovascular hemodynamics in young and aged beagle dogs. Japanese journal of pharmacology, 1981, Volume: 31, Issue:2 Topics: Age Factors; Animals; Dogs; Dose-Response Relationship, Drug; Female; Hemodynamics; Male; Niacinamide; Nicorandil; Nitrates; Nitroglycerin; Vasodilator Agents	1981
Glibenclamide-induced oscillation of canine coronary artery is independent of myocardial ischemia. Journal of cardiovascular pharmacology, 1994, Volume: 23, Issue:3 Topics: Adenosine Triphosphate; Animals; Arginine; Benzopyrans; Coronary Circulation; Coronary Vessels; Cromakalim; Diltiazem; Dogs; Female; Glyburide; In Vitro Techniques; Male; Muscle Tonus; Muscle, Smooth, Vascular; Myocardial Ischemia; Niacinamide; Nicorandil; Nitroarginine; Nitroglycerin; Potassium Channels; Pyrroles; Vasodilator Agents	1994
Comparative study on the effects of intracoronary nicorandil and nitroglycerin in ischaemic, reperfused porcine hearts. European heart journal, 1995, Volume: 16, Issue:5 Topics: Animals; Female; Hemodynamics; Injections, Intra-Arterial; Male; Niacinamide; Nicorandil; Nitroglycerin; Oxygen Consumption; Potassium Channels; Reperfusion Injury; Swine; Vasodilator Agents	1995
Effect of KRN2391 on venous return: comparison with other vasodilators. Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:1 Topics: Animals; Benzopyrans; Cromakalim; Dogs; Female; Glyburide; Hemodynamics; Male; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Potassium Channels; Pyridines; Pyrroles; Vasodilator Agents; Veins	1993
The inhibitory mechanisms of nicorandil in isolated rat urinary bladder and femoral artery. European journal of pharmacology, 1995, Jan-24, Volume: 273, Issue:1-2 Topics: Acetylcholine; Animals; Benzopyrans; Cromakalim; Cyclic GMP; Electric Stimulation; Femoral Artery; Guanylate Cyclase; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Potassium Channels; Potassium Chloride; Pyrroles; Rats; Rats, Wistar; Urinary Bladder; Vasodilator Agents	1995
Effects of nicorandil and glyceryl trinitrate on infarct size, adenosine release, and neutrophil infiltration in the dog. Cardiovascular research, 1995, Volume: 29, Issue:4 Topics: Adenosine; Animals; Cell Movement; Coronary Circulation; Dogs; Female; Male; Myocardial Infarction; Myocardial Reperfusion; Myocardium; Neutrophils; Niacinamide; Nicorandil; Nitroglycerin; Peroxidase; Regional Blood Flow; Vasodilator Agents	1995
Antioxidative action of the nitrovasodilator nicorandil: inhibition of oxidative activation of liver microsomal glutathione S-transferase and lipid peroxidation. Japanese journal of pharmacology, 1994, Volume: 65, Issue:3 Topics: Animals; Antioxidants; Dose-Response Relationship, Drug; Enzyme Activation; Glutathione Transferase; Isosorbide Dinitrate; Lipid Peroxidation; Male; Microsomes, Liver; Niacinamide; Nicorandil; Nitroglycerin; Oxidation-Reduction; Propanolamines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Structure-Activity Relationship; Sympathetic Nervous System; Vasodilator Agents	1994
New antianginal nitro esters with reduced hypotensive activity. Synthesis and pharmacological evaluation of 3-[(nitrooxy)alkyl]-2H-1,3-benzoxazin-4(3H)-ones. Journal of medicinal chemistry, 1995, Jan-06, Volume: 38, Issue:1 Topics: Angina Pectoris; Animals; Benzoxazines; Blood Pressure; Hemodynamics; Hypotension; In Vitro Techniques; Ischemia; Male; Niacinamide; Nicorandil; Nitrates; Nitroglycerin; Oxazines; Rabbits; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Vasodilator Agents	1995
Comparisons of the effects of nicorandil, pinacidil, nicardipine and nitroglycerin on coronary vessels in the conscious dog: role of the endothelium. British journal of pharmacology, 1995, Volume: 114, Issue:2 Topics: Acetylcholine; Animals; Blood Pressure; Coronary Circulation; Coronary Vessels; Dogs; Endothelium, Vascular; Guanidines; Heart Rate; Niacinamide; Nicardipine; Nicorandil; Nitroglycerin; Pinacidil; Vascular Resistance; Vasodilator Agents	1995
The contribution of guanylate cyclase stimulation and K+ channel opening to nicorandil-induced vasorelaxation depends on the conduit vessel and on the nature of the spasmogen. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:3 Topics: Animals; Aorta; Enzyme Activation; Guanylate Cyclase; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Niacinamide; Nicorandil; Nitroglycerin; Norepinephrine; Picolines; Potassium Channels; Potassium Chloride; Pulmonary Artery; Pyrans; Rabbits; Vascular Resistance; Vasodilator Agents	1994
Long term increases in coronary arterial conductance during five day infusion of low dose nicorandil. Cardiovascular research, 1994, Volume: 28, Issue:6 Topics: Animals; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Delivery Systems; Female; Male; Niacinamide; Nicorandil; Nitroglycerin; Time Factors; Vasodilator Agents	1994
Inhibitory effects of nicorandil on sympathetic coronary vasoconstriction. Cardiovascular research, 1994, Volume: 28, Issue:6 Topics: Animals; Arginine; Coronary Vessels; Dogs; Electric Stimulation; Neuropeptide Y; Niacinamide; Nicorandil; Nitroarginine; Nitroglycerin; Norepinephrine; Sympathetic Nervous System; Vascular Resistance; Vasoconstriction	1994
Effects of a novel dihydropyridine calcium antagonist on venous capacitance in Wistar-Kyoto rats. Drugs under experimental and clinical research, 1994, Volume: 20, Issue:2 Topics: Animals; Blood Pressure; Blood Volume; Calcium Channel Blockers; Drug Interactions; Ethanol; Hemodynamics; Hexamethonium Compounds; Male; Niacinamide; Nifedipine; Nitroglycerin; Phenylephrine; Rats; Rats, Inbred WKY; Sympathectomy, Chemical; Vascular Resistance	1994
Cytoprotective effects of nicorandil on hypothermic injury to immature cardiac myocytes--comparison with nitroglycerin, diltiazem and prostaglandin E1. Japanese circulation journal, 1994, Volume: 58, Issue:8 Topics: Alprostadil; Animals; Cells, Cultured; Cold Temperature; Creatine Kinase; Cryopreservation; Cryoprotective Agents; Diltiazem; Heart; L-Lactate Dehydrogenase; Myocardium; Niacinamide; Nicorandil; Nitroglycerin; Rats; Vasodilator Agents	1994
Mechanisms of vasodilation of cerebral vessels induced by the potassium channel opener nicorandil in canine in vivo experiments. Stroke, 1994, Volume: 25, Issue:8 Topics: Administration, Topical; Animals; Arterioles; Benzopyrans; Cromakalim; Dimethyl Sulfoxide; Dogs; Glyburide; Methylene Blue; Microcirculation; Niacinamide; Nicorandil; Nitroglycerin; Pia Mater; Pyrroles; Vasodilation; Vasodilator Agents; Venules	1994
In vitro protective effects of nicorandil on hypothermic injury to immature cardiac myocytes: comparison with nitroglycerin. Cardiovascular drugs and therapy, 1994, Volume: 8, Issue:1 Topics: Animals; Cell Survival; Cells, Cultured; Creatine Kinase; Heart; Hypothermia; L-Lactate Dehydrogenase; Male; Myocardial Contraction; Myocardium; Niacinamide; Nicorandil; Nitroglycerin; Organ Preservation; Rats; Rats, Wistar; Vasodilator Agents	1994
Mechanism of the vasodilatory action of nicorandil on coronary circulation in dogs. Cardiovascular drugs and therapy, 1994, Volume: 8, Issue:1 Topics: Animals; Benzopyrans; Coronary Circulation; Coronary Vessels; Cromakalim; Dogs; Dose-Response Relationship, Drug; Female; Glyburide; Hemodynamics; Injections, Intravenous; Male; Niacinamide; Nicorandil; Nitroglycerin; Potassium Channels; Pyrroles; Vasodilator Agents	1994
Effects of nicorandil on cytosolic calcium concentrations and on tension development in the rabbit femoral artery. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:2 Topics: Animals; Benzopyrans; Calcium; Cromakalim; Cyclic GMP; Femoral Artery; Glyburide; In Vitro Techniques; Male; Niacinamide; Nicorandil; Nitroglycerin; Norepinephrine; Potassium; Potassium Channels; Pyrroles; Rabbits; Vasodilation; Vasodilator Agents	1994
Effect of nicorandil on post-ischaemic contractile dysfunction in the heart: roles of its ATP-sensitive K+ channel opening property and nitrate property. Clinical and experimental pharmacology & physiology, 1993, Volume: 20, Issue:9 Topics: Adenosine Triphosphate; Animals; Glyburide; Hemodynamics; Infusions, Intravenous; Ion Channel Gating; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardial Stunning; Niacinamide; Nicorandil; Nitrates; Nitroglycerin; Potassium Channels; Premedication; Rabbits; Vasodilator Agents	1993
Vasorelaxant mechanism of KRN2391 and nicorandil in porcine coronary arteries of different sizes. British journal of pharmacology, 1993, Volume: 109, Issue:3 Topics: Animals; Benzopyrans; Coronary Vessels; Cromakalim; Glyburide; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Oxyhemoglobins; Potassium Channels; Pyridines; Pyrroles; Swine; Vasodilator Agents	1993
Protection by nicorandil against the dysfunction of the central vagal baroreflex system following transient global cerebral ischaemia in dogs. British journal of pharmacology, 1993, Volume: 109, Issue:4 Topics: Animals; Aorta, Thoracic; Blood Pressure; Cerebrovascular Circulation; Dogs; Female; Heart Rate; Ischemic Attack, Transient; Male; Niacinamide; Nicardipine; Nicorandil; Nitroglycerin; Pressoreceptors; Reflex; Stereotaxic Techniques; Vagus Nerve; Vasodilator Agents	1993
Activation of ATP-dependent K+ channels enhances myocardial protection due to cold high potassium cardioplegia: a force-frequency relationship study. Journal of molecular and cellular cardiology, 1995, Volume: 27, Issue:9 Topics: Animals; Cold Temperature; Glyburide; Guinea Pigs; Heart; Heart Arrest, Induced; Ion Channel Gating; Muscle Contraction; Myocardium; Niacinamide; Nicorandil; Nitroglycerin; Potassium; Potassium Channels; Vasodilator Agents	1995
Cardiovascular interactions characterizing the vasodilator components of nicorandil in conscious dogs. Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:5 Topics: Animals; Blood Pressure; Cyclic GMP; Dogs; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Heart Rate; Male; Niacinamide; Nicorandil; Nitroglycerin; Potassium Channels; Vasodilator Agents	1995
Comparison of the effects of nicorandil, pinacidil and nitroglycerin on hypoxic and hypercapnic pulmonary vasoconstriction in the isolated perfused lung of rat. British journal of pharmacology, 1996, Volume: 117, Issue:4 Topics: Acidosis; Animals; Guanidines; Hypercapnia; Hypoxia; In Vitro Techniques; Lung; Male; Niacinamide; Nicorandil; Nitric Oxide; Nitroglycerin; Pinacidil; Potassium Channel Blockers; Rats; Rats, Wistar; Vasoconstriction; Vasodilator Agents	1996
KATP channel activation mediates nicorandil-induced relaxation of nitrate-tolerant coronary arteries. Journal of cardiovascular pharmacology, 1996, Volume: 27, Issue:6 Topics: Animals; Coronary Vessels; Dose-Response Relationship, Drug; Drug Tolerance; Glyburide; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Potassium Channels; Swine; Vasodilator Agents	1996
Infarct size-reducing effect of nicorandil is mediated by the KATP channel but not by its nitrate-like properties in dogs. Cardiovascular research, 1996, Volume: 32, Issue:2 Topics: Adenosine; Animals; Dogs; Female; Glyburide; Ion Channel Gating; Male; Methylene Blue; Myocardial Infarction; Myocardial Reperfusion; Myocardium; Niacinamide; Nicorandil; Nitric Oxide; Nitroglycerin; Potassium Channels; Vasodilator Agents	1996
Effect of the new nitrate ester ITF 296 on coronary and systemic hemodynamics in the conscious dog: comparison with nitroglycerin and nicorandil. Journal of cardiovascular pharmacology, 1995, Volume: 26 Suppl 4 Topics: Animals; Benzoxazines; Coronary Circulation; Coronary Vessels; Dogs; Female; Hemodynamics; Injections, Intravenous; Male; Niacinamide; Nicorandil; Nitrates; Nitroglycerin; Oxazines; Vasodilator Agents	1995
Effect of JTV-506, a novel vasodilator, on coronary blood flow in conscious dogs. Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:3 Topics: Administration, Oral; Animals; Benzopyrans; Blood Pressure; Chromans; Coronary Circulation; Cromakalim; Diltiazem; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Injections, Intravenous; Male; Niacinamide; Nicorandil; Nitroglycerin; Pyrroles; Vasodilator Agents	1997
Heterogeneity in the vasorelaxing effect of nicorandil on dog epicardial coronary arteries: comparison with other NO donors. Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:6 Topics: Animals; Atrial Natriuretic Factor; Benzopyrans; Coronary Vessels; Cromakalim; Cyclic GMP; Dogs; Female; Glyburide; In Vitro Techniques; Male; Methylene Blue; Molsidomine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitric Oxide; Nitroglycerin; Nitroprusside; Oxyhemoglobins; Pyrroles; Vasodilator Agents	1997
Vasodilation profile of CD-832, a novel dihydropyridine derivative in rabbit aorta. General pharmacology, 1997, Volume: 29, Issue:3 Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Calcium Channel Blockers; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Niacinamide; Nicorandil; Nifedipine; Nitrendipine; Nitroglycerin; Norepinephrine; Potassium Chloride; Rabbits; Vasodilation; Vasodilator Agents	1997
Synthesis and biological activity of novel 2-(alpha-alkoxyimino)benzylpyridine derivatives as K+ channel openers. Chemical & pharmaceutical bulletin, 1997, Volume: 45, Issue:12 Topics: Administration, Oral; Animals; Aorta, Thoracic; Blood Pressure; Coronary Circulation; Cromakalim; Cyclic N-Oxides; Diltiazem; Dogs; Hypertension; Male; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Potassium Channels; Pyridines; Rats; Rats, Inbred SHR; Rats, Wistar; Structure-Activity Relationship; Vasodilation; Vasodilator Agents	1997
Beneficial hemodynamic effects of nicorandil in a canine model of acute congestive heart failure: comparison with nitroglycerin and cromakalim. Fundamental & clinical pharmacology, 1998, Volume: 12, Issue:3 Topics: Acute Disease; Animals; Blood Pressure; Coronary Circulation; Cromakalim; Disease Models, Animal; Dogs; Female; Heart; Heart Failure; Heart Rate; Male; Myocardial Contraction; Myocardium; Niacinamide; Nicorandil; Nitroglycerin; Saponins; Vasodilator Agents	1998