niacinamide has been researched along with methotrexate in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (23.08) | 18.7374 |
| 1990's | 2 (7.69) | 18.2507 |
| 2000's | 3 (11.54) | 29.6817 |
| 2010's | 10 (38.46) | 24.3611 |
| 2020's | 5 (19.23) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Zackheim, HS | 1 |
| Enomoto, T; Tanuma, S; Yamada, M | 1 |
| Besseghir, K; Mosig, D; Roch-Ramel, F | 1 |
| Birdsall, B; Feeney, J; Hammond, SJ; Roberts, GC; Tendler, SJ | 1 |
| Krakoff, IH | 1 |
| Bache, K; Ehrlich, W; Hauschild, A; Kröger, H; Krüger, D; Ohde, M; Thefeld, W | 1 |
| Bache, K; Hauschild, A; Kröger, H; Krüger, D; Ohde, M; Thefeldt, W; Voigt, WP | 1 |
| WILLIAMS, DC | 1 |
| Ainavarapu, SR; Badilla, CL; Fernandez, JM; Li, L | 1 |
| Ainavarapu, SR; Fernandez, JM; Li, L | 1 |
| Kitamura, S; Moriyasu, A; Ohta, S; Sugihara, K; Tayama, Y | 1 |
| Borradori, L; Daniel, BS; Hall, RP; Murrell, DF | 1 |
| Abali, EE; Adebisi Lawal, R; Banerjee, D; Bertino, JR; Hsieh, YC; Johnson-Farley, N; Kerrigan, JE; Lee, KC; Scotto, K; Tedeschi, P | 1 |
| Hagström, MV; Hirvonen, JT; Kaasalainen, MH; Mäkilä, EM; Salonen, JJ; Santos, HA; Wang, CF | 1 |
| Dinçaslan, H; Ensari, A; Kiremitçi, S; Özçakar, ZB; Taktak, A; Yalçınkaya, F; Yılmaz, S | 1 |
| Durmus, S; Schinkel, AH; van Hoppe, S | 1 |
| Garg, JP; Genovese, MC; Gutierrez-Ureña, SR; Kivitz, AJ; Kristy, R; Poiley, J; Shay, K; Wang, X; Zubrzycka-Sienkiewicz, A | 1 |
| Albrecht, LV; Bui, MH; De Robertis, EM | 1 |
| Feng, Q; Guo, M; Qiu, Q; Tan, X | 1 |
| Iwasaki, M; Izutsu, H; Kaneko, Y; Katayama, K; Kawakami, A; Rokuda, M; Shiomi, T; Takeuchi, T; Tanaka, S; Tanaka, Y; Ushijima, S; van der Heijde, D; Yamada, E | 1 |
| Chen, YH; Izutsu, H; Kaneko, Y; Kawakami, A; Nakashima, Y; Rokuda, M; Shiomi, T; Song, YW; Takeuchi, T; Tanaka, S; Tanaka, Y; Ushijima, S; Yamada, E | 1 |
| Akinlade, B; Cao, Y; Chindalore, V; Moy, S; Sawamoto, T; Valluri, U; Zhang, W; Zhu, T | 1 |
| Pang, M; Tang, Y; Wang, M; Wang, W; Wang, Y; Xu, Y; Yang, X | 1 |
| Fukuda, M; Izutsu, H; Kaneko, Y; Kato, D; Rokuda, M; Schultz, NM; Takeuchi, T; Tanaka, Y | 1 |
| Hsieh, CY; Tsai, TF | 1 |
4 review(s) available for niacinamide and methotrexate
| Article | Year |
|---|---|
Evidence-based management of bullous pemphigoid.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Autoantibodies; Azathioprine; Clinical Trials as Topic; Dermatologic Agents; Evidence-Based Medicine; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Methotrexate; Niacinamide; Pemphigoid, Bullous; Randomized Controlled Trials as Topic | 2011 |
The impact of Organic Anion-Transporting Polypeptides (OATPs) on disposition and toxicity of antitumor drugs: Insights from knockout and humanized mice.
Topics: Animals; Antineoplastic Agents; Camptothecin; Doxorubicin; Drug Interactions; Gene Expression; Hepatocytes; Humans; Inactivation, Metabolic; Irinotecan; Liver; Liver-Specific Organic Anion Transporter 1; Methotrexate; Mice; Mice, Transgenic; Neoplasms; Niacinamide; Organic Cation Transport Proteins; Phenylurea Compounds; Platinum Compounds; Sorafenib; Taxoids | 2016 |
JAK3-selective inhibitor peficitinib for the treatment of rheumatoid arthritis.
Topics: Adamantane; Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Cell Proliferation; Humans; Janus Kinase 3; Janus Kinase Inhibitors; Methotrexate; Niacinamide; Piperidines; Pyrimidines; Pyrroles | 2019 |
Management of Coexisting Bullous Pemphigoid and Psoriasis: A Review.
Topics: Acitretin; Adrenal Cortex Hormones; Anti-Bacterial Agents; Azathioprine; Biological Factors; Biological Products; Cyclosporins; Dermatologic Agents; Etanercept; Humans; Immunosuppressive Agents; Methotrexate; Niacinamide; Pemphigoid, Bullous; Psoriasis; Rituximab; Ustekinumab; Vitamins | 2022 |
6 trial(s) available for niacinamide and methotrexate
| Article | Year |
|---|---|
Treatment of psoriasis with 6-aminonicotinamide.
Topics: Acid-Base Equilibrium; Administration, Oral; Administration, Topical; Adult; Aged; Amines; Biopsy; Clinical Trials as Topic; Female; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Niacinamide; Nicotinic Acids; Psoriasis; Skin; Solvents | 1975 |
Peficitinib, a JAK Inhibitor, in the Treatment of Moderate-to-Severe Rheumatoid Arthritis in Patients With an Inadequate Response to Methotrexate.
Topics: Adamantane; Antirheumatic Agents; Arthritis, Rheumatoid; Double-Blind Method; Female; Humans; Janus Kinases; Male; Methotrexate; Middle Aged; Niacinamide; Severity of Illness Index; Treatment Outcome | 2017 |
Efficacy and safety of peficitinib (ASP015K) in patients with rheumatoid arthritis and an inadequate response to methotrexate: results of a phase III randomised, double-blind, placebo-controlled trial (RAJ4) in Japan.
Topics: Adamantane; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Double-Blind Method; Drug Substitution; Female; Herpes Zoster; Humans; Immunosuppressive Agents; Infections; Janus Kinase Inhibitors; Japan; Male; Methotrexate; Middle Aged; Niacinamide; Severity of Illness Index; Treatment Outcome | 2019 |
Safety and effectiveness of peficitinib (ASP015K) in patients with rheumatoid arthritis: interim data (22.7 months mean peficitinib treatment) from a long-term, open-label extension study in Japan, Korea, and Taiwan.
Topics: Adamantane; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; C-Reactive Protein; Female; Herpes Zoster; Humans; Janus Kinase Inhibitors; Japan; Male; Methotrexate; Middle Aged; Nasopharyngitis; Niacinamide; Republic of Korea; Severity of Illness Index; Taiwan; Treatment Outcome | 2020 |
Investigation of Potential Drug-Drug Interactions between Peficitinib (ASP015K) and Methotrexate in Patients with Rheumatoid Arthritis.
Topics: Adamantane; Adult; Antirheumatic Agents; Area Under Curve; Arthritis, Rheumatoid; Drug Interactions; Female; Half-Life; Humans; Male; Methotrexate; Middle Aged; Niacinamide | 2020 |
Patient- and physician-reported outcomes from two phase 3 randomized studies (RAJ3 and RAJ4) of peficitinib (ASP015K) in Asian patients with rheumatoid arthritis.
Topics: Adamantane; Antirheumatic Agents; Arthritis, Rheumatoid; Double-Blind Method; Humans; Methotrexate; Niacinamide; Patient Reported Outcome Measures; Physicians; Treatment Outcome | 2021 |
16 other study(ies) available for niacinamide and methotrexate
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Effect of thymidine on poly(ADP-ribosyl)ation in vivo.
Topics: Cell Nucleus; DNA Replication; DNA, Neoplasm; HeLa Cells; Humans; Hydroxyurea; Kinetics; Methotrexate; Niacinamide; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Thymidine | 1979 |
Facilitation by serum albumin of renal tubular secretion of organic anions.
Topics: Animals; Dextrans; In Vitro Techniques; Kidney Tubules, Proximal; Kinetics; Methotrexate; Niacinamide; p-Aminohippuric Acid; Protein Binding; Rabbits; Serum Albumin, Bovine | 1989 |
Dihydrofolate reductase: multiple conformations and alternative modes of substrate binding.
Topics: Escherichia coli; Hydrogen-Ion Concentration; Lacticaseibacillus casei; Ligands; Magnetic Resonance Spectroscopy; Methotrexate; Models, Molecular; NADH, NADPH Oxidoreductases; NADP; Niacinamide; Protein Conformation; Substrate Specificity; Tetrahydrofolate Dehydrogenase | 1989 |
Increase in uric acid biosynthesis produced by 2-substituted thiadiazoles.
Topics: Azaserine; Azoles; Diazooxonorleucine; Mercaptopurine; Methotrexate; Niacinamide; Nicotinic Acids; Tryptophan; Uric Acid | 1965 |
Enhancement of the effect of methotrexate on collagen II induced arthritis in mice by nicotinamide.
Topics: Alanine Transaminase; Animals; Antirheumatic Agents; Arthritis; Aspartate Aminotransferases; Cattle; Collagen; Drug Synergism; Luminescent Measurements; Male; Methotrexate; Mice; Mice, Inbred DBA; Niacinamide; Respiratory Burst | 1998 |
Nicotinamide and methionine reduce the liver toxic effect of methotrexate.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Antirheumatic Agents; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Liver Diseases; Male; Methionine; Methotrexate; Mice; Mice, Inbred DBA; Niacinamide | 1999 |
THE RELATIONSHIP BETWEEN 3 ALPHA-HYDROXYSTEROID NICOTINAMIDE NUCLEOTIDE COENZYME TRANSHYDROGENATION AND BETA-GLUCURONIDASE IN REGENERATING RAT LIVER.
Topics: Androsterone; Coenzymes; Dialysis; Glucuronates; Glucuronidase; Heparin; Hepatectomy; Hydroxysteroids; Lactones; Liver; Liver Extracts; Liver Regeneration; Mercaptopurine; Methotrexate; NAD; NADP; Niacin; Niacinamide; Nucleotides; Oxidoreductases; Perfusion; Pharmacology; Rats; Renal Dialysis; Research; Spectrophotometry | 1964 |
Ligand binding modulates the mechanical stability of dihydrofolate reductase.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biophysical Phenomena; Biophysics; CHO Cells; Chromatography, Affinity; Cricetinae; Folic Acid; Folic Acid Antagonists; Humans; Ligands; Methotrexate; Microscopy, Atomic Force; NAD; NADP; Niacinamide; Proteasome Endopeptidase Complex; Protein Binding; Protein Conformation; Protein Denaturation; Protein Engineering; Protein Folding; Protein Transport; Spectrophotometry; Stress, Mechanical; Tensile Strength; Tetrahydrofolate Dehydrogenase; Thermodynamics | 2005 |
Fingerprinting DHFR in single-molecule AFM studies.
Topics: Animals; Biophysical Phenomena; Biophysics; CHO Cells; Chromatography, Affinity; Cricetinae; Cricetulus; Folic Acid; Folic Acid Antagonists; Humans; Ligands; Methotrexate; Microscopy, Atomic Force; NAD; NADP; Niacinamide; Peptide Mapping; Proteasome Endopeptidase Complex; Protein Binding; Protein Conformation; Protein Denaturation; Protein Engineering; Protein Folding; Protein Transport; Spectrophotometry; Stress, Mechanical; Tensile Strength; Tetrahydrofolate Dehydrogenase; Thermodynamics | 2006 |
Developmental changes of aldehyde oxidase in postnatal rat liver.
Topics: Age Factors; Aldehyde Oxidase; Animals; Benzaldehydes; Blotting, Western; Cytosol; Hydroxylation; Liver; Methotrexate; Niacinamide; Oxidation-Reduction; Rats; Rats, Sprague-Dawley | 2007 |
Enhanced degradation of dihydrofolate reductase through inhibition of NAD kinase by nicotinamide analogs.
Topics: Biological Transport; Cell Line, Tumor; Half-Life; Humans; Methotrexate; NADP; Niacinamide; Phosphotransferases (Alcohol Group Acceptor); Proteolysis; Tetrahydrofolate Dehydrogenase; Transcription, Genetic; Up-Regulation | 2013 |
Dual-drug delivery by porous silicon nanoparticles for improved cellular uptake, sustained release, and combination therapy.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; Delayed-Action Preparations; Drug Delivery Systems; Endocytosis; Humans; Methotrexate; Nanoparticles; Niacinamide; Particle Size; Phenylurea Compounds; Porosity; Silicon; Sorafenib; Spectroscopy, Fourier Transform Infrared; Static Electricity | 2015 |
Anti-VEGF-related thrombotic microangiopathy in a child presenting with nephrotic syndrome.
Topics: Adolescent; Angiogenesis Inhibitors; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Bone Neoplasms; Cisplatin; Doxorubicin; Humans; Ifosfamide; Male; Methotrexate; Nephrotic Syndrome; Niacinamide; Osteosarcoma; Phenylurea Compounds; Proteinuria; Remission, Spontaneous; Sorafenib; Thrombotic Microangiopathies; Vascular Endothelial Growth Factor A; Withholding Treatment | 2016 |
Canonical Wnt is inhibited by targeting one-carbon metabolism through methotrexate or methionine deprivation.
Topics: Carbon; Endosomes; Glycogen Synthase Kinase 3 beta; HEK293 Cells; HeLa Cells; Humans; Lysosomes; Methionine; Methotrexate; Methylation; Niacinamide; Protein-Arginine N-Methyltransferases; Repressor Proteins; S-Adenosylmethionine; Wnt Signaling Pathway | 2019 |
Co-delivery of methotrexate and nicotinamide by cerosomes for topical psoriasis treatment with enhanced efficacy.
Topics: Administration, Topical; Animals; Imiquimod; Methotrexate; Mice; Mice, Inbred BALB C; Niacinamide; Psoriasis; Skin | 2021 |