niacinamide has been researched along with kynurenine in 72 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 52 (72.22) | 18.7374 |
| 1990's | 3 (4.17) | 18.2507 |
| 2000's | 5 (6.94) | 29.6817 |
| 2010's | 6 (8.33) | 24.3611 |
| 2020's | 6 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Badawy, AA; Evans, M | 1 |
| Bühlen, E; Bühner, R; Byrd, DJ; Kochen, W | 1 |
| Kimmig, J; Kreysel, HW; Meyerhoff, K | 1 |
| Allegri, G; Costa, C; Crepaldi, G; De Antoni, A; Muggeo, M | 3 |
| Beisel, WR; Dinterman, RE; Powanda, MC; Wannemacher, RW | 1 |
| Brenner, A; Wapnir, RA | 1 |
| Annable, L; Chouinard, G; Sourkes, TL; Young, SN | 1 |
| Beaudoin, AR | 1 |
| Bender, DA; Njagi, EN | 2 |
| Bender, DA | 2 |
| Lester, G | 1 |
| Brown, RR; Madsen, PO; Price, JM; Wolf, H | 1 |
| Brown, RR; Hankes, LV; Lippincott, S; Schmaeler, M | 2 |
| Arakawa, T; Morikawa, T; Tada, K | 1 |
| Pasquariello, G; Tenconi, LT | 1 |
| Brown, RR; Hankes, LV; Schiffer, L; Schmaeler, M | 1 |
| Brown, RR; Hankes, LV | 1 |
| Luvarà, A; Magni, LA; Mainardi, L | 1 |
| Brown, RR; Leklem, JE; Woodford, J | 1 |
| Brown, RR; Price, JM; Rose, DP; Wolf, H | 1 |
| Bianchi-Donnasibilla, L; Curró, F; Luvara, A | 1 |
| Brown, RR; Burney, SW; Friedell, GH; Price, JM | 1 |
| Hardy, J; Heeley, AF; Heeley, ME; Soothill, JF | 1 |
| Brown, AT; Wagner, C | 1 |
| Brown, RR; Hankes, LV; Leklem, JE; Schmaeler, M | 1 |
| Brune, GG; Brune, RM; Wiskemann, A | 1 |
| Leklem, JE | 1 |
| Brown, RR; Hankes, LV; Leklem, JE; Mekel, RC | 1 |
| Curzon, G; Green, AR | 1 |
| Berg, CP; Loh, HH | 1 |
| Alperovitch, A; Bohuon, C; Chabenat, C; Flamant, R | 1 |
| Birnbaum, D; Böttcher, F; Samsonova, IA | 1 |
| Houpt, JB; Hunt, M; Ogryzlo, MA | 1 |
| Wolf, H | 1 |
| Mangoni, A | 1 |
| Kuntze, I; Schievelbein, H | 1 |
| McGinty, F; Rose, DP | 1 |
| Braidman, IP; Rose, DP | 1 |
| Brown, RR; Hankes, LV; Jansen, CR; Leklem, J; Mekel, RC | 1 |
| Scholz, G; Streffer, C | 1 |
| Streffer, C | 1 |
| Møller, SE | 1 |
| Perkins, MN; Stone, TW | 1 |
| Bender, DA; Magboul, BI | 1 |
| Lapin, IP | 1 |
| Braga, O; Brew, BJ; Grant, RS; Guillemin, GJ; Kerr, SJ; Smythe, GA; Walker, DW | 1 |
| DELAEY, P; HOOFT, C; SNOECK, J; TIMMERMANS, J | 1 |
| HUANG, PC; KAO, MS; LIU, DK | 1 |
| PASQUARIELLO, G | 1 |
| MAINARDI, L; TENCONI, LT | 1 |
| CHIANCONE, FM | 1 |
| Fukuwatari, T; Ohta, M; Sasaki, R; Shibata, K; Toriochi, M | 1 |
| Arvidsson, B; Bergquist, J; Bowyer, JF; Casida, JE; Dobrovolsky, VN; Doerge, DR; Heflich, RH; Pabarcus, MK; Williams, LD | 1 |
| Cwik, M; Llenos, IC; Miller, CL; Walkup, J; Weis, S | 1 |
| Egashira, Y; Sanada, H; Sasaki, N | 1 |
| Fukuwatari, T; Hiratsuka, C; Saito, K; Sano, M; Sasaki, S; Shibata, K | 1 |
| Fukuwatari, T; Funakoshi, H; Kadota, E; Kanai, M; Nakamura, T; Sano, M; Shibata, K; Terakata, M | 1 |
| da Cunha, DF; Maltos, AL; Monteiro, MC; Moraes, GV; Portari, GV; Vannucchi, H | 1 |
| Bipath, P; Levay, PF; Viljoen, M | 1 |
| Cooper, C; Crozier, SR; El-Heis, S; Godfrey, KM; Harvey, NC; Inskip, HM; Robinson, SM | 1 |
| Makino, R; Okuyama, H; Tachibana, T; Tomonaga, S | 1 |
| Becquemont, L; Boniface, B; Boursier-Neyret, C; Chanson, P; Colle, R; Corruble, E; David, DJ; Falissard, B; Fève, B; Masson, P; Verstuyft, C; Walther, B; Werner, E | 1 |
| Berge, RK; Bjørndal, B; Lindquist, C; Lund, A; Nygård, O; Skorve, J; Slettom, G; Svardal, A | 1 |
| Badawy, AA | 1 |
| Davidson, JA; Frank, BS; Jaggers, J; Khailova, L; Klawitter, J; Twite, M; Urban, TT | 1 |
| Fathi, M; Hajibeygi, R; Jazi, K; Klegeris, A; McElhinney, A; Sayehmiri, F; Shool, S; Sodeifian, F; Tavasol, A; Tavirani, MR; Vakili, K; Yaghoobpoor, S | 1 |
| Axelsson, J; Balter, LJ; Erhardt, S; Lasselin, J; Lekander, M; Li, X; Olsson, MJ; Schwieler, L | 1 |
4 review(s) available for niacinamide and kynurenine
| Article | Year |
|---|---|
Quantitative aspects of tryptophan metabolism in humans and other species: a review.
Topics: Age Factors; Amides; Animals; Carbon Isotopes; Cats; Dogs; Female; Glucuronates; Glycine; Hippurates; Humans; Hydroxyindoleacetic Acid; Indican; Kynurenic Acid; Kynurenine; Lysine; Male; Mice; Niacinamide; Nicotinic Acids; ortho-Aminobenzoates; Pyridines; Pyridones; Pyridoxine; Rats; Serotonin; Sex Factors; Species Specificity; Swine; Time Factors; Tryptophan; Xanthurenates | 1971 |
Excretion of tryptophan metabolites as affected by pregnancy, contraceptive steroids, and steroid hormones.
Topics: Androsterone; Animals; Contraceptives, Oral; Enzyme Induction; Estradiol; Female; Humans; Hydrocortisone; Kynurenine; Liver; Male; Megestrol; NAD; Niacinamide; ortho-Aminobenzoates; Pregnancy; Pyridoxine; Rats; Tryptophan; Tryptophan Oxygenase; Xanthurenates | 1971 |
Immunotherapy of COVID-19 with poly (ADP-ribose) polymerase inhibitors: starting with nicotinamide.
Topics: Basic Helix-Loop-Helix Transcription Factors; Betacoronavirus; Cell Line; Coronavirus Infections; COVID-19; Cytokines; Humans; Immunotherapy; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Niacinamide; Pandemics; Pneumonia, Viral; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Receptors, Aryl Hydrocarbon; SARS-CoV-2 | 2020 |
Dynamic changes in metabolites of the kynurenine pathway in Alzheimer's disease, Parkinson's disease, and Huntington's disease: A systematic Review and meta-analysis.
Topics: 3-Hydroxyanthranilic Acid; Adenosine; Alzheimer Disease; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; NAD; Niacinamide; Parkinson Disease; Tryptophan | 2022 |
4 trial(s) available for niacinamide and kynurenine
| Article | Year |
|---|---|
Tryptophan-nicotinamide, imipramine and their combination in depression. A controlled study.
Topics: Adult; Bipolar Disorder; Clinical Trials as Topic; Depression; Double-Blind Method; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Female; Humans; Imipramine; Kynurenine; Male; Middle Aged; Niacinamide; Psychiatric Status Rating Scales; Tryptophan | 1979 |
Studies on tryptophan metabolism in male subjects treated with female sex hormones.
Topics: Aminohippuric Acids; Chlorotrianisene; Chromatography, Ion Exchange; Clinical Trials as Topic; Diethylstilbestrol; Glucuronates; Humans; Indican; Isonicotinic Acids; Kynurenic Acid; Kynurenine; Male; Mestranol; Niacinamide; Norethindrone; Norethynodrel; ortho-Aminobenzoates; Progestins; Prostatic Diseases; Prostatic Hyperplasia; Prostatitis; Pyridones; Pyridoxine; Spectrophotometry; Tryptophan; Tryptophan Oxygenase; Xanthurenates | 1970 |
Supplementing healthy women with up to 5.0 g/d of L-tryptophan has no adverse effects.
Topics: Adolescent; Adult; Biomarkers; Body Mass Index; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Female; Humans; Kynurenic Acid; Kynurenine; Niacinamide; ortho-Aminobenzoates; Placebos; Tryptophan; Young Adult | 2013 |
Lipopolysaccharide-induced changes in the kynurenine pathway and symptoms of sickness behavior in humans.
Topics: Adult; Female; Humans; Illness Behavior; Kynurenic Acid; Kynurenine; Lipopolysaccharides; Niacinamide; Young Adult | 2023 |
64 other study(ies) available for niacinamide and kynurenine
| Article | Year |
|---|---|
The regulation of rat liver tryptophan pyrrolase activity by reduced nicotinamide-adenine dinucleotide (phosphate). Experiments with glucose and nicotinamide.
Topics: Animals; Diet; Fructose; Glucose; Kynurenine; Liver; Male; Methylphenazonium Methosulfate; NAD; NADP; Niacinamide; Rats; Sucrose; Time Factors; Tryptophan Oxygenase | 1976 |
[Studies on tryptophan metabolism in untreated phenylketonuric patients].
Topics: Acetophenones; Adolescent; Adult; Biotransformation; Child; Child, Preschool; Chromatography, Ion Exchange; Chromatography, Thin Layer; Female; Humans; Kynurenic Acid; Kynurenine; Male; Mass Spectrometry; Niacinamide; Nicotinic Acids; ortho-Aminobenzoates; Phenylalanine; Phenylketonurias; Quinolines; Tryptophan; Xanthurenates | 1975 |
[Tryptophan-load in progressive scleroderma (author's transl)].
Topics: 3-Hydroxyanthranilic Acid; Female; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Kynurenine; Male; Niacinamide; Scleroderma, Systemic; Serotonin; Skin; Tryptamines; Tryptophan; Xanthurenates | 1976 |
Tryptophan metabolism "via" nicotimic acid in patients with scleroderma.
Topics: Adult; Aged; Female; Humans; Kynurenine; Middle Aged; Niacinamide; Nicotinic Acids; Pyridoxine; Scleroderma, Localized; Scleroderma, Systemic; Tryptophan | 1976 |
Tryptophan metabolism in relation to amino acid alterations during typhoid fever.
Topics: Amino Acids; Humans; Kynurenine; Liver; Niacinamide; Tryptophan; Typhoid Fever; Xanthurenates | 1975 |
A pyridoxine-dependent behavioral disorder unmasked by isoniazid.
Topics: Child Behavior Disorders; Child, Preschool; Female; Humans; Hyperkinesis; Isoniazid; Kynurenine; Niacinamide; Pyridoxine; Substance Withdrawal Syndrome; Tryptophan | 1978 |
NAD precursors as antiteratogens against aminothiadiazole.
Topics: Animals; Dose-Response Relationship, Drug; Female; Fetal Resorption; Gestational Age; Kynurenine; Male; NAD; Niacinamide; Nicotinic Acids; Pregnancy; Quinolinic Acids; Rats; Teratogens; Thiadiazoles; Tryptophan | 1976 |
Tryptophan metabolism in mice infected with Schistosoma mansoni.
Topics: Animals; Cells, Cultured; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Liver; Male; Mice; Niacinamide; Schistosomiasis mansoni; Serotonin; Tryptophan; Xanthurenates | 1991 |
Inhibition of tryptophan----niacin metabolism by dietary leucine and by leucine and 2-oxo-isocaproate in vitro.
Topics: Animals; Cells, Cultured; Depression, Chemical; Dietary Proteins; Keto Acids; Kynurenine; Leucine; Liver; NADP; Niacin; Niacinamide; Pellagra; Rats; Tryptophan; Xanthurenates | 1991 |
Schistosoma mansoni: effects on tryptophan metabolism in mice.
Topics: Animals; Chemical Phenomena; Chemistry; Kynurenic Acid; Kynurenine; Liver; Male; Mice; Niacinamide; Oxidation-Reduction; Pyridoxine; Schistosomiasis mansoni; Tryptophan | 1990 |
Effects of a dietary excess of leucine and of the addition of leucine and 2-oxo-isocaproate on the metabolism of tryptophan and niacin in isolated rat liver cells.
Topics: Animals; Caproates; In Vitro Techniques; Keto Acids; Kynurenine; Leucine; Liver; Male; NAD; Niacin; Niacinamide; Rats; Rats, Inbred Strains; Tryptophan; Xanthurenates | 1989 |
End-product regulation of the tryptophan-nicotinic acid pathway in Neurospora crassa.
Topics: Arylformamidase; Cell-Free System; Culture Media; Fluorometry; Hydrolases; Kynurenine; Neurospora; Niacinamide; Nicotinic Acids; ortho-Aminobenzoates; Spectrophotometry; Spores, Fungal; Tryptophan; Tryptophan Oxygenase | 1971 |
Effects of L-tryptophan load on the metabolism of tryptophan-2-C14 in man.
Topics: Aged; Aminohippuric Acids; Carbon Dioxide; Female; Humans; Kynurenic Acid; Kynurenine; Male; Middle Aged; Niacinamide; Pyridines; Pyridones; Tryptophan; Tryptophan Oxygenase; Xanthurenates | 1967 |
Tryptophan load and uptake of tryptophan by leukocytes in Hartnup disease.
Topics: Adolescent; Amino Acids; Chromatography, Paper; Female; Hartnup Disease; Humans; Indoleacetic Acids; Kynurenine; Leukocytes; Male; Niacinamide; Tryptophan | 1966 |
[Elimination of the metabolites of the tryptophan--nicotinic acid pathway after corticoid treatment in the rat].
Topics: Adrenal Cortex Hormones; Animals; Hippurates; Hydrocortisone; Kynurenine; Niacinamide; Nicotinic Acids; Rats; Tryptophan; Xanthurenates | 1967 |
Tryptophan metabolism in humans with various types of anemias.
Topics: Adult; Aged; Anemia; Carbon Dioxide; Carbon Isotopes; Child; Female; Humans; Kynurenine; Male; Middle Aged; Niacinamide; ortho-Aminobenzoates; Pyridines; Pyridones; Pyridoxine; Spirometry; Thalassemia; Tryptophan; Tryptophan Oxygenase | 1968 |
Metabolism of D- and L-kynurenine-keto-14C in rats and the effects of unlabeled enantiomers.
Topics: Animals; Autoradiography; Carbon Dioxide; Carbon Isotopes; Chromatography, Paper; Injections, Intraperitoneal; Kynurenic Acid; Kynurenine; Methods; Niacinamide; Nicotinic Acids; Pyridines; Rats; Stereoisomerism; Xanthurenates | 1968 |
[Observations on the urinary elimination of N-methylnicotinamide after administration of prednisolone to newborn infants].
Topics: Animals; Humans; Infant, Newborn; Kynurenine; Male; Niacinamide; Prednisolone; Rats | 1969 |
Comparative tryptophan metabolism in cats and rats: differences in adaptation of tryptophan oxygenase and in vivo metabolism of tryptophan, kynurenine and hydroxykynurenine.
Topics: Amino Acids; Aminohippuric Acids; Animals; Cats; Enzyme Induction; Glucuronates; Hydrocortisone; Indican; Kynurenic Acid; Kynurenine; Male; Niacinamide; ortho-Aminobenzoates; Phenylbutyrates; Rats; Species Specificity; Sulfates; Tryptophan; Tryptophan Oxygenase; Urinary Bladder Neoplasms; Xanthurenates | 1969 |
Tryptophan metabolism as affected by anovulatory agents.
Topics: Aminohippuric Acids; Chlorotrianisene; Diethylstilbestrol; Estrogens; Female; Humans; Isoniazid; Kynurenine; Male; Menstruation; Mestranol; Niacinamide; Nicotinic Acids; Norethynodrel; Ovulation; Pregnancy; Progesterone; Pyridoxine; Scleroderma, Systemic; Tryptophan; Urinary Bladder Neoplasms; Vitamin B 6 Deficiency; Xanthurenates | 1969 |
[Observations on tryptophan-nicotinic acid metabolism after a load of tryptophan and lysine in rats with pyridoxine deficiency].
Topics: Animals; Chromatography; Kynurenine; Lysine; Niacinamide; Nicotinic Acids; Rats; Tryptophan; Vitamin B 6 Deficiency; Xanthurenates | 1969 |
Lack of effect of smoking on the excretion of tryptophan metabolites by man.
Topics: Adult; Aminohippuric Acids; Female; Glucuronates; Humans; Kynurenic Acid; Kynurenine; Male; Middle Aged; Niacinamide; Pyridinium Compounds; Smoking; Tryptophan; Urinary Bladder Neoplasms; Xanthurenates | 1970 |
A disorder of tryptophan metabolism in chronic granulomatous disease.
Topics: Child; Child, Preschool; Chromatography, Paper; Chronic Disease; Granuloma; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infections; Kynurenic Acid; Kynurenine; Lymphadenitis; Male; Niacinamide; Pyridoxine; Tryptophan; Xanthurenates | 1970 |
Regulation of tryptophan pyrrolase activity in Xanthomonas pruni.
Topics: Ascorbic Acid; Heme; Kinetics; Kynurenine; Niacinamide; Nicotinic Acids; ortho-Aminobenzoates; Porphyrins; Tryptophan Oxygenase; Xanthomonas | 1970 |
The influence of nicotinamide on the urinary excretion of tryptophan metabolites in Hodgkin's disease.
Topics: Adolescent; Adult; Amino Acids; Female; Hodgkin Disease; Humans; Kynurenine; Male; Metabolism; Middle Aged; Niacinamide; ortho-Aminobenzoates; Phenylbutyrates; Pyridoxine; Tryptophan; Xanthurenates | 1970 |
Tryptophan metabolism in the cat: a study with carbon-14-labeled compounds.
Topics: Aminohippuric Acids; Animals; Carbon Dioxide; Carbon Isotopes; Cat Diseases; Cats; Kynurenine; Male; Niacinamide; Nicotinic Acids; ortho-Aminobenzoates; Picolinic Acids; Pyridines; Tryptophan; Urinary Bladder Neoplasms; Xanthurenates | 1971 |
[Tryptophan metabolism in patients with pellagra].
Topics: Acetaminophen; Administration, Oral; Adult; Aged; Child, Preschool; Female; Hartnup Disease; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Kynurenine; Middle Aged; Niacinamide; Pellagra; Tryptamines; Tryptophan | 1970 |
Tryptophan metabolism in patients with pellagra: problem of vitamin B 6 enzyme activity and feedback control of tryptophan pyrrolase enzyme.
Topics: Black or African American; Black People; Feedback; Female; Humans; Kynurenine; Male; Niacinamide; Nicotinic Acids; Pellagra; Pyridines; Pyridones; Pyridoxine; South Africa; Tryptophan; Tryptophan Oxygenase; United States; White People; Xanthurenates | 1971 |
The effect of tryptophan metabolites on brain 5-hydroxytryptamine metabolism.
Topics: Alanine; Allopurinol; Amino Acids; Animals; Brain; Brain Chemistry; Carbon Isotopes; Carboxy-Lyases; Histamine; Kynurenic Acid; Kynurenine; Male; Methanol; Methyldopa; Mixed Function Oxygenases; Niacinamide; Nicotinic Acids; Nitroglycerin; ortho-Aminobenzoates; Phenylalanine; Phenylbutyrates; Picolinic Acids; Pyridines; Pyridoxal Phosphate; Pyridoxine; Rats; Serotonin; Sulfuric Acids; Time Factors; Tryptophan; Tryptophan Oxygenase; Xanthurenates | 1970 |
Conversion of D-tryptophan to nicotinic acid in the rat.
Topics: Animals; Deficiency Diseases; Indoles; Kidney; Kynurenic Acid; Kynurenine; Liver; Male; Niacinamide; Nicotinic Acids; ortho-Aminobenzoates; Pyruvates; Rats; Stereoisomerism; Sulfuric Acids; Tryptophan; Xanthurenates | 1971 |
[Absence of change in urinary levels of metabolites of tryptophan and tobacco].
Topics: Adult; Female; Humans; Kynurenine; Male; Niacinamide; Nicotiana; ortho-Aminobenzoates; Phenols; Plants, Toxic; Smoking; Tryptophan | 1971 |
The influence of simultaneous administration of vitamin B 6 and nicotinamide on tryptophan metabolism in Hodgkin's disease.
Topics: Acylation; Administration, Oral; Aminohippuric Acids; Hodgkin Disease; Humans; Hydroxylation; Infusions, Parenteral; Kynurenic Acid; Kynurenine; Methyl Ethers; Niacinamide; ortho-Aminobenzoates; Pyridoxine; Tryptophan; Xanthurenates | 1972 |
[Biosynthesis of nicotinic acid in Rhodotorula glutinis].
Topics: Kynurenine; Mitosporic Fungi; Mutation; Neurospora; Niacinamide; Nicotinic Acids; ortho-Aminobenzoates; Radiation Genetics; Tryptophan; Ultraviolet Rays | 1972 |
Tryptophan metabolism in man (with special reference to rheumatoid arthritis and scleroderma).
Topics: Arthritis, Rheumatoid; Aspirin; Cystinuria; Drug Synergism; Edetic Acid; Humans; Kynurenic Acid; Kynurenine; Methods; Niacinamide; Penicillamine; Pyridoxine; Scleroderma, Systemic; Tryptophan; Xanthurenates | 1973 |
The effect of hormones and vitamin B6 on urinary excretion of metabolites of the kynurenine pathway.
Topics: Adolescent; Adult; Aged; Androgens; Animals; Estrogens; Female; Humans; Hydrocortisone; Hydrolases; Indican; Isoniazid; Kynurenine; Male; Menstruation; Middle Aged; Niacinamide; Nicotinic Acids; ortho-Aminobenzoates; Pregnancy; Pyridones; Pyridoxine; Rats; Transaminases; Tryptophan | 1974 |
The "kynurenine shunt" and depression.
Topics: Adrenal Glands; Adrenalectomy; Amitriptyline; Animals; Antidepressive Agents; Depression; Humans; Imipramine; Kynurenine; Liver; Niacinamide; Psychiatric Status Rating Scales; Rats; Tranylcypromine; Tryptophan Oxygenase; Xanthurenates | 1974 |
[Proceedings: Tryptophan metabolism, bladder carcinoma and smoking habits].
Topics: 3-Hydroxyanthranilic Acid; Carcinoma; Humans; Kynurenine; Niacinamide; Smoking; Tryptophan; Urinary Bladder Neoplasms | 1972 |
The influence of adrenocortical hormones and vitamins upon tryptophan metabolism in man.
Topics: Adrenocorticotropic Hormone; Adult; Benzoates; Breast Neoplasms; Female; Humans; Hydrocortisone; Kynurenine; Liver; Male; Niacinamide; Pyridoxine; Riboflavin; Stimulation, Chemical; Stress, Physiological; Tryptophan; Tryptophan Oxygenase; Xanthurenates | 1968 |
Abnormal tryptophan metabolism in patients with scurvy-type skin.
Topics: Acetates; Adult; Aminohippuric Acids; Black or African American; Black People; Ethnicity; Glucuronates; Hemosiderosis; Humans; Indoles; Kynurenic Acid; Kynurenine; Male; NAD; Niacinamide; Nicotinic Acids; ortho-Aminobenzoates; Pyridines; Scurvy; South Africa; Sulfuric Acids; Tryptophan; Xanthurenates | 1973 |
Metabolism of pyridine nucleotides and its relation to DNA synthesis in regenerating mouse liver.
Topics: Adenine Nucleotides; Animals; DNA; Female; Hepatectomy; Hydrolases; Kynurenine; Liver; Liver Regeneration; Mice; Mice, Inbred Strains; NAD; Niacinamide; Nicotinamide Mononucleotide; Nucleotidyltransferases; ortho-Aminobenzoates; Pentosyltransferases; Transaminases; Tryptophan | 1972 |
[Proceedings: NAD biosynthesis from tryptophan in mouse liver].
Topics: Animals; DNA; Hydrolases; Kynurenine; Liver; Liver Regeneration; Mice; NAD; Niacinamide; Nicotinic Acids; Thymidine; Tryptophan | 1972 |
Pharmacokinetics of tryptophan, renal handling of kynurenine and the effect of nicotinamide on its appearance in plasma and urine following L-tryptophan loading of healthy subjects.
Topics: Adult; Female; Humans; Kidney; Kinetics; Kynurenine; Male; Niacinamide; Tryptophan; Tryptophan Oxygenase | 1981 |
An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid.
Topics: Acetylcholine; Animals; Aspartic Acid; Cerebral Cortex; Convulsants; Drug Interactions; Kynurenic Acid; Kynurenine; Male; N-Methylaspartate; Neuromuscular Depolarizing Agents; Niacinamide; Oxadiazoles; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats | 1982 |
The effects of a dietary excess of leucine on the synthesis of nicotinamide nucleotides in the rat.
Topics: Animals; Diet; Enzyme Activation; Hydrolases; Kynurenine; Leucine; Liver; Male; NADP; Niacin; Niacinamide; Pellagra; Rats; Rats, Inbred Strains; Tryptophan; Tryptophan Oxygenase | 1983 |
Nicotinamide, inosine and hypoxanthine, putative endogenous ligands of the benzodiazepine receptor, opposite to diazepam are much more effective against kynurenine-induced seizures than against pentylenetetrazol-induced seizures.
Topics: Animals; Anticonvulsants; Binding, Competitive; Diazepam; Hypoxanthines; Inosine; Kynurenine; Ligands; Male; Mice; Mice, Inbred Strains; Niacinamide; Pentylenetetrazole; Receptors, Drug; Receptors, GABA-A; Seizures | 1981 |
Concurrent quantification of quinolinic, picolinic, and nicotinic acids using electron-capture negative-ion gas chromatography-mass spectrometry.
Topics: Animals; Female; Fetus; Gas Chromatography-Mass Spectrometry; Humans; Kynurenine; Niacin; Niacinamide; Picolinic Acids; Quinolinic Acid; Sheep | 2002 |
BIOCHEMICAL ASPECTS OF THE HARTNUP DISEASE. II. SOME OBSERVATIONS ON RATS ABOUT TRYPTOPHAN METABOLISM.
Topics: Child; Clinical Enzyme Tests; Hartnup Disease; Humans; Indican; Indoles; Kidney; Kynurenine; Metabolic Diseases; Neomycin; Niacin; Niacinamide; Nicotinic Acids; Nystatin; Pellagra; Rats; Renal Aminoacidurias; Tryptophan; Urine | 1964 |
METABOLISM OF 3-HYDROXYANTHRANILIC ACID-CARBOXYL-C14 IN THE HUMAN.
Topics: 3-Hydroxyanthranilic Acid; Achondroplasia; Blood; Carbon Isotopes; Chromatography; Hippurates; Humans; Kynurenic Acid; Kynurenine; Metabolism; Niacin; Niacinamide; Nicotinic Acids; ortho-Aminobenzoates; Pyridines; Rats; Research; Tryptophan; Urine; Xanthurenates | 1964 |
THE METABOLISM OF ALPHA-N-MONOMETHYL-L-TRYPTOPHAN (L-ABRIN) IN MAN AND IN NORMAL AND PYRIDOXINE DEFICIENT RATS.
Topics: Abrin; Amino Acids; Body Fluids; Eclampsia; Female; Humans; Kynurenine; Male; Niacin; Niacinamide; Pregnancy; Pyridoxine; Rats; Research; Tryptophan; Urine; Vitamin B 6 Deficiency; Xanthurenates | 1964 |
[RESEARCH ON THE TRYPTOPHAN--NICOTINIC ACID PATHWAY IN DIABETES MELLITUS].
Topics: Diabetes Mellitus; Geriatrics; Hippurates; Insulin; Kynurenic Acid; Kynurenine; Metabolism; Niacin; Niacinamide; Nicotinic Acids; Research; Tryptophan; Urine | 1964 |
[CONTRIBUTION TO THE STUDY OF METABOLITES OF THE TRYPTOPHAN TO NICOTINIC ACID PATHWAY IN RELATION TO SEX].
Topics: Humans; Kynurenic Acid; Kynurenine; Metabolism; Niacin; Niacinamide; Nicotinic Acids; Research; Sex; Tryptophan; Urine; Xanthurenates | 1964 |
[ELIMINATION OF METABOLITES OF TRYPTOPHAN IN THE PYRIDOXINE-DEFICIENT RAT AFTER DIFFERENT DOSES OF TRYPTOPHAN AND IN DIVERSE URINARY FRACTIONS].
Topics: Body Fluids; Hippurates; Kynurenine; Metabolism; Niacin; Niacinamide; Pyridoxine; Rats; Research; Tryptophan; Urinary Tract; Urine; Vitamin B 6 Deficiency; Xanthurenates | 1965 |
[Metabolic disturbance of tryptophan-nicotinamide conversion pathway by putative endocrine disruptors, bisphenol A and styrene monomer].
Topics: Animals; Benzhydryl Compounds; Body Weight; Eating; Hydrolases; Kynurenine; Liver; Male; Niacinamide; Phenols; Rats; Styrene; Tryptophan | 2004 |
Effect of arylformamidase (kynurenine formamidase) gene inactivation in mice on enzymatic activity, kynurenine pathway metabolites and phenotype.
Topics: Animals; Arylformamidase; Gene Silencing; Kidney; Kynurenine; Liver; Lymphocyte Activation; Mice; Mice, Knockout; Niacinamide; Phenotype; Renal Insufficiency; Thymidine Kinase; Tryptophan | 2005 |
Alterations in kynurenine precursor and product levels in schizophrenia and bipolar disorder.
Topics: 3-Hydroxyanthranilic Acid; Adult; Biomarkers; Bipolar Disorder; Brain; Chromatography, High Pressure Liquid; Female; Gyrus Cinguli; Humans; Kynurenine; Middle Aged; Niacinamide; Predictive Value of Tests; Schizophrenia; Signal Transduction; Suicide; Tryptophan; Tryptophan Oxygenase | 2008 |
Production of L-tryptophan-derived catabolites in hepatocytes from streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Carboxy-Lyases; Diabetes Mellitus, Experimental; Hepatocytes; Kynurenine; Male; Niacinamide; Picolinic Acids; Quinolinic Acid; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tritium; Tryptophan; Water | 2009 |
The niacin required for optimum growth can be synthesized from L-tryptophan in growing mice lacking tryptophan-2,3-dioxygenase.
Topics: 3-Hydroxyanthranilic Acid; Animals; Body Weight; Diet; Female; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenic Acid; Kynurenine; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Niacin; Niacinamide; Quinolinic Acid; Tryptophan; Tryptophan Oxygenase; Xanthurenates | 2013 |
Niacin metabolism and indoleamine 2,3-dioxygenase activation in malnourished patients with flaky paint dermatosis.
Topics: Acute-Phase Reaction; Adult; Aged; C-Reactive Protein; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Indoles; Kwashiorkor; Kynurenine; Middle Aged; Niacin; Niacinamide; Pellagra; Skin; Skin Diseases; Tryptophan | 2015 |
The kynurenine pathway activities in a sub-Saharan HIV/AIDS population.
Topics: Acquired Immunodeficiency Syndrome; Adult; Africa South of the Sahara; Antiretroviral Therapy, Highly Active; Case-Control Studies; CD4 Lymphocyte Count; Cross-Sectional Studies; Cytokines; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Gas Chromatography-Mass Spectrometry; HIV Infections; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Interferon-gamma; Interleukin-6; Kynurenine; Male; Middle Aged; Neopterin; Niacinamide; Pentosyltransferases; Poverty; Quinolinic Acid; South Africa; Tryptophan | 2015 |
Higher maternal serum concentrations of nicotinamide and related metabolites in late pregnancy are associated with a lower risk of offspring atopic eczema at age 12 months.
Topics: Adult; Age Factors; Biomarkers; Comorbidity; Dermatitis, Atopic; Female; Humans; Infant; Kynurenine; Male; Maternal Exposure; Metabolic Networks and Pathways; Niacinamide; Odds Ratio; Pregnancy; Prenatal Exposure Delayed Effects; Prognosis; Risk; Risk Factors | 2016 |
Effects of high ambient temperature on plasma metabolomic profiles in chicks.
Topics: Amino Acids, Sulfur; Animals; Chickens; Cystathionine; Cysteine; Cystine; Environmental Exposure; Gas Chromatography-Mass Spectrometry; Homocysteine; Hot Temperature; Kynurenine; Molecular Weight; Niacinamide; Oxidative Stress; Quinolinic Acid; Taurine; Tryptophan | 2018 |
Peripheral tryptophan, serotonin, kynurenine, and their metabolites in major depression: A case-control study.
Topics: 3-Hydroxyanthranilic Acid; Adult; Case-Control Studies; Cohort Studies; Depressive Disorder, Major; Female; Humans; Kynurenine; Male; Middle Aged; Niacinamide; Picolinic Acids; Serotonin; Tryptophan; Xanthurenates | 2020 |
Increased fatty acid oxidation and mitochondrial proliferation in liver are associated with increased plasma kynurenine metabolites and nicotinamide levels in normolipidemic and carnitine-depleted rats.
Topics: Animals; Carnitine; Cell Proliferation; Kynurenine; Lipid Metabolism; Liver; Male; Metabolic Networks and Pathways; Methylhydrazines; Mitochondria; NAD; Niacinamide; Oxidation-Reduction; Peroxisomes; Rats; Tryptophan | 2020 |
Serum metabolic profile of postoperative acute kidney injury following infant cardiac surgery with cardiopulmonary bypass.
Topics: Acute Kidney Injury; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Humans; Infant; Kynurenine; Metabolome; Methionine; Niacinamide; Postoperative Complications; Purines | 2021 |