niacinamide and ketoconazole

niacinamide has been researched along with ketoconazole in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cihon, F; Gallentine, M; Lathia, C; Lettieri, J; Radtke, M; Sundaresan, P1
Chen, L; Heath, EI; Ingram, M; Lorusso, P; Malburg, L; McGreivy, J; Melara, R; Pilat, MJ; Sun, YN; Wiezorek, J; Yan, L1
Aggarwal, AK; Jain, S1
Banovic, F; Linder, KE; Olivry, T1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1

Trials

1 trial(s) available for niacinamide and ketoconazole

ArticleYear
Effect of coadministration of ketoconazole, a strong CYP3A4 inhibitor, on pharmacokinetics and tolerability of motesanib diphosphate (AMG 706) in patients with advanced solid tumors.
    Investigational new drugs, 2008, Volume: 26, Issue:5

    Topics: Aged; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Administration Schedule; Female; Humans; Indoles; Ketoconazole; Male; Middle Aged; Neoplasms; Niacinamide; Oligonucleotides

2008

Other Studies

5 other study(ies) available for niacinamide and ketoconazole

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Lack of effect of ketoconazole-mediated CYP3A inhibition on sorafenib clinical pharmacokinetics.
    Cancer chemotherapy and pharmacology, 2006, Volume: 57, Issue:5

    Topics: Adult; Antifungal Agents; Benzenesulfonates; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Humans; Ketoconazole; Male; Middle Aged; Niacinamide; Phenylurea Compounds; Pyridines; Sorafenib

2006
Physicochemical characterization and dissolution study of solid dispersions of ketoconazole with nicotinamide.
    Chemical & pharmaceutical bulletin, 2011, Volume: 59, Issue:5

    Topics: Antifungal Agents; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Chemistry, Physical; Hydrogen-Ion Concentration; Ketoconazole; Kinetics; Niacinamide; Solubility; Spectroscopy, Fourier Transform Infrared; Vitamin B Complex; X-Ray Diffraction

2011
Ciclosporin therapy for canine generalized discoid lupus erythematosus refractory to doxycycline and niacinamide.
    Veterinary dermatology, 2014, Volume: 25, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Cyclosporine; Dermatologic Agents; Dog Diseases; Dogs; Doxycycline; Drug Therapy, Combination; Ketoconazole; Lupus Erythematosus, Discoid; Male; Niacinamide; Treatment Failure; Treatment Outcome

2014
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016