niacinamide has been researched along with isonicotinamide in 74 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (10.81) | 18.7374 |
| 1990's | 4 (5.41) | 18.2507 |
| 2000's | 18 (24.32) | 29.6817 |
| 2010's | 36 (48.65) | 24.3611 |
| 2020's | 8 (10.81) | 2.80 |
| Authors | Studies |
|---|---|
| Awai, M; Kawabata, T; Mori, M; Ogino, T | 1 |
| Barra, R; Lanighan, K; Lea, MA; Randolph, V; Sumas, M | 1 |
| Toth, B | 1 |
| Funae, Y; Nemoto, N; Sakurai, J | 1 |
| Ogata, S; Okumura, K; Taguchi, H; Takeuchi, M | 1 |
| Taguchi, H | 1 |
| Fujita, H; Ogata, S; Okumura, K; Shibata, K; Taguchi, H; Takeuchi, M | 1 |
| An, D; Li, YS; Wang, Y; Wu, J; Zhang, Z | 1 |
| Frank, P; Ghosh, P; Hodgson, KO; Taube, H | 1 |
| CLARK, BB; ETSTEN, B | 1 |
| MARCHETTI, G; NOLI, S | 1 |
| WERNER, I | 1 |
| CLARK, BB; SMITH, ER | 1 |
| BURCHENAL, JH; COLEY, VC; KRAKOFF, IH; OETTGEN, HF; PURPLE, JR | 1 |
| PURCELL, WP; SINGER, JA | 1 |
| Bubnovskaya, L; Campanella, L; Ganusevich, I; Kovelskaya, A; Levitin, I; Osinsky, S; Sigan, A; Valkovskaya, N; Wardman, P | 1 |
| Moir, RD; Sauve, AA; Schramm, VL; Willis, IM | 1 |
| Kang, SK; Kim, CH; Lee, JH; Lee, YC | 1 |
| Bäckesjö, CM; Haldosén, LA; Li, Y; Lindgren, U | 2 |
| Ghaderi, N; Hatcher, ME; Leskowitz, GM; Mueller, LJ; Olsen, RA; Pederson, K | 1 |
| Doro, FG; Rodrigues-Filho, UP; Tfouni, E | 1 |
| Barrow, JC; Collusi, D; Espeseth, AS; Graham, SL; Gregro, AR; Hochman, JH; Holloway, MK; Lai, MT; McGaughey, GB; Munshi, SK; Nantermet, PG; Pietrak, BL; Rittle, KE; Selnick, HG; Shaffer, JR; Simon, AJ; Stanton, MG; Stauffer, SR; Steinbeiser, MA; Vacca, JP | 1 |
| Borba, A; Fausto, R; Gómez-Zavaglia, A | 1 |
| Arnott, G; Blaney, E; Brice, H; Clayden, J | 1 |
| Báthori, NB; Bourne, SA; Lemmerer, A | 1 |
| Smith, G; Wermuth, UD; White, JM | 1 |
| Hu, J; Yeung, K; Zhu, Y | 1 |
| Aleman, G; Chaco, E; Chiang, CM; Hakimi, P; Hanson, RW; Kong, X; Liu, GE; Martins-Santos, ME; Samols, D; Wu, SY; Yang, J | 1 |
| Daković, M; Popović, Z | 1 |
| Baur, JA | 1 |
| Cauchon, N; Cheetham, J; Liu, M; Ostovic, J; Ren, D; Ronk, M; Zhou, ZS | 1 |
| Back, K; Boyd, S; Chadwick, K; Davey, RJ; Seaton, CC | 1 |
| Carlos, IZ; Castellano, EE; de Souza, RA; Leite, CQ; Mauro, AE; Netto, AV; Pavan, FR; Stevanato, A; Treu-Filho, O | 1 |
| Bourne, SA; Caira, MR; Li, J | 1 |
| Arenas, A; Cabiscol, E; Nierga, C; Reverter-Branchat, G; Rodríguez-Colman, MJ; Ros, J; Sorolla, MA; Tamarit, J | 1 |
| Bastos, LF; Coelho, MM; Ferreira, WC; Godin, AM; Merlo, LA; Nascimento, EB; Paiva, AL; Rocha, LT; Seniuk, JG | 1 |
| Desiraju, GR; Dubey, R; Hathwar, VR; Pavan, MS; Row, TN; Thakur, TS | 1 |
| Kavuru, P; Shytle, RD; Smith, AJ; Wojtas, L; Zaworotko, MJ | 1 |
| Kang, YG; Kim, EC; Kim, SJ; Lee, SI; Lee, YM; Park, KH | 1 |
| Maqani, N; McClure, JM; Smith, JS; Wierman, MB | 1 |
| Desiraju, GR; Tothadi, S | 1 |
| Arenas, JF; Castro, JL; Lopez-Ramirez, MR; Otero, JC; Soto, J | 1 |
| Brice, H; Clayden, J; Senczyszyn, J | 1 |
| Matczak-Jon, E; Slepokura, K; Sowa, M | 1 |
| Chiba, Y; Fukaya, M; Ido-Kitamura, Y; Inoue, Y; Kaneki, M; Kitamura, T; Mao, J; Tamura, Y; Tanioka, T; Waeber, C; Yamada, M | 1 |
| Hong, C; Li, G; Shen, H; Xie, Y; Yao, Y; Yuan, X | 1 |
| Bu, X; Chen, J; Jiang, Y; Li, W; Liu, K; Wu, J; Xu, Y; Xue, J; Yang, L; Zhang, G; Zhao, G | 1 |
| Chen, C; Lin, Y; Mei, X; Pan, G; Wang, JR; Yu, X; Zhou, C | 1 |
| Bekiranov, S; Li, M; Matecic, M; Smith, DL; Smith, JS; Valsakumar, V; Wierman, MB | 1 |
| Huang, CC; Liu, JJ; Ou, XP; Shi, W | 1 |
| Ali, MS; El-Asmy, AA; Jeragh, B | 1 |
| Chan, HM; Sung, HH; Tong, HH; Zheng, Y; Zhou, Z | 1 |
| Arora, V; Burton, CR; Cao, Y; Chen, L; Clarke, WJ; Dubowchik, GM; Kish, K; Krause, CM; Langley, DR; Lewis, HA; Lippy, J; Liu, N; Luo, G; Macor, JE; Pokross, M; Raybon, J; Sivaprakasam, P; Snow, K; Xiao, H | 1 |
| Bielenica, A; Caliendo, G; Capasso, R; Ciano, A; Corvino, A; Di Vaio, P; Fiorino, F; Frecentese, F; Izzo, AA; Kędzierska, E; Magli, E; Massarelli, P; Nencini, C; Orzelska-Gòrka, J; Perissutti, E; Rossi, I; Santagada, V; Severino, B | 1 |
| Deng, Z; Fu, X; Li, J; Ren, Q; Wang, L; Ye, YQ; Zhang, H | 1 |
| Haldar, M; Mallik, S; Srivastava, DK; Yu, J | 1 |
| Andrews, GP; Jones, DS; Li, S; McCoy, CP; Tian, Y; Yu, T | 1 |
| Churakov, AV; Drozd, KV; Manin, AN; Perlovich, GL | 1 |
| Gao, M; Wang, M; Zheng, QH | 1 |
| Ouyang, J; Zeng, QZ; Zhang, L; Zhang, S | 1 |
| Bao, J; Mei, X; Wang, JR; Yan, Z; Yu, Q | 1 |
| Healy, AM; Madi, AM; O'Connell, P; Serrano, DR; Twamley, B; Walsh, D; Worku, ZA | 1 |
| Cui, W; Fan, Q; Feng, N; He, Z; Zhang, Y | 1 |
| Kai, S; Li Na, D; Ling, F; Man, Z; Wen, L; Xiao-Hui, Z; Yan-Jie, H; Yu-Zhen, Y | 1 |
| Calvet, T; Ejarque, D; Font-Bardia, M; Pons, J; Sánchez-Férez, F | 1 |
| Chadha, R; Chakraborti, S; Grewal, MK; Jindal, A; Tomar, S | 1 |
| Aitipamula, S; Das, S | 1 |
| Chen, J; Chen, Y; Cui, J; Feng, P; Han, Y; Hu, K; Huang, S; Li, H; Li, L; Tang, G; Wang, J; Yang, S; Zhong, Y | 1 |
| Meng, FH; Tu, S; Zhang, TJ; Zhang, X; Zhang, Y; Zhang, ZH | 1 |
| Bebiano, SS; Bimbo, LM; Jones, ECL; Oswald, IDH; Ward, MR | 1 |
| Cai, Y; Deng, X; Lei, J; Li, Q; Li, Y; Shen, Y; Sun, Y; Yang, B | 1 |
| He, M; Liu, L; Sun, X; Wang, P; Yang, X; Zhang, Y; Zhao, H; Zhao, J; Zhu, Z | 1 |
| Almeida, AA; Boroni, M; Bressan, GC; Caetano, MMM; de Andrade Barros, MV; de Oliveira Santos, L; de Oliveira, LL; de Paiva, JC; de Souza, APM; do Vale, JA; Fietto, JLR; Gonçalves, VHS; Guimarães, GR; Machado-Neves, M; Martim, FRG; Moreira, GA; Silva, LVG; Silva-Júnior, A; Teixeira, RR | 1 |
2 review(s) available for niacinamide and isonicotinamide
| Article | Year |
|---|---|
[Vitamins and apoptosis--induction of apoptosis in human cancer cells by nicotinic acid-related compounds].
Topics: Apoptosis; Caspase Inhibitors; HeLa Cells; HL-60 Cells; Humans; K562 Cells; Neoplasms; Niacinamide; Nicotinic Acids; Picolinic Acids | 1999 |
Biochemical effects of SIRT1 activators.
Topics: Animals; Cardiotonic Agents; Energy Metabolism; Enzyme Activation; Heterocyclic Compounds, 4 or More Rings; Humans; Insulin Resistance; Learning; Longevity; Memory; Mice; Models, Biological; NAD; Neoplasms; Niacinamide; O-Acetyl-ADP-Ribose; Resveratrol; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 1; Stilbenes | 2010 |
72 other study(ies) available for niacinamide and isonicotinamide
| Article | Year |
|---|---|
Effects of nicotinamide and its isomers on iron-induced renal damage.
Topics: Amides; Animals; Creatinine; DNA Damage; Ferric Compounds; Kidney; Kidney Tubular Necrosis, Acute; Lipid Peroxidation; Male; Malondialdehyde; Niacinamide; Nitrilotriacetic Acid; Picolinic Acids; Rats; Rats, Wistar | 1992 |
Effects of nicotinamide, isonicotinamide, and bleomycin on DNA synthesis and repair in rat hepatocytes and hepatoma cells.
Topics: Animals; Bleomycin; Cell Division; DNA Repair; DNA Replication; Hydroxyurea; Liver; Liver Neoplasms, Experimental; Niacinamide; Rats; Rats, Inbred BUF | 1982 |
Lack of carcinogenicity of nicotinamide and isonicotinamide following lifelong administration to mice.
Topics: Animals; Diet; Female; Male; Mice; Neoplasms, Experimental; Niacinamide; Structure-Activity Relationship; Time Factors | 1983 |
Maintenance of phenobarbital-inducible Cyp2b gene expression in C57BL/6 mouse hepatocytes in primary culture as spheroids.
Topics: Animals; Base Sequence; Cells, Cultured; Culture Techniques; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Enzyme Induction; Gene Expression Regulation, Enzymologic; Liver; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Niacinamide; Oxidoreductases; Phenobarbital; RNA, Messenger | 1995 |
Apoptosis induced by niacin-related compounds in HL-60 cells.
Topics: Apoptosis; Caspase Inhibitors; DNA Fragmentation; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Enzyme Inhibitors; Flow Cytometry; HL-60 Cells; Humans; Iron Chelating Agents; Microscopy, Fluorescence; Niacin; Niacinamide; Picolinic Acids | 1998 |
Apoptosis induced by niacin-related compounds in K562 cells but not in normal human lymphocytes.
Topics: Antineoplastic Agents; Apoptosis; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphocytes; Niacin; Niacinamide; Peroxides; Picolinic Acids; Reactive Oxygen Species | 2000 |
Surface-enhanced raman spectra of some anti-tubercle bacillus drugs.
Topics: Antitubercular Agents; Isoniazid; Niacinamide; Pyrazinamide; Spectrum Analysis, Raman | 2000 |
Cooperative ligation, back-bonding, and possible pyridine-pyridine interactions in tetrapyridine-vanadium(II): a visible and X-ray spectroscopic study.
Topics: Crystallography, X-Ray; Electrochemistry; Ligands; Models, Molecular; Niacinamide; Oxidation-Reduction; Pyridines; Spectrophotometry, Ultraviolet; Vanadium | 2002 |
Pharmacologic and antiarrhythmic actions of ambonestyl (2-diethylaminoethyl-isonicotinamide) in man; preliminary report.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrocardiography; Humans; Niacin; Niacinamide; Nicotinic Acids | 1955 |
[Effect of 2-diethylaminoethyl isonicotinamide on some basic properties of myocardium & experimental arrhythmias].
Topics: Arrhythmias, Cardiac; Heart; Myocardium; Niacin; Niacinamide; Nicotinic Acids | 1957 |
The effect of 2-diethylaminoethyl-isonicotinamide on cardiac arrhythmia in man.
Topics: Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Heart Conduction System; Humans; Male; Niacin; Niacinamide; Nicotinic Acids | 1957 |
The actions of ambonestyl [N(2-diethylaminoethyl)-isonicotinamide] and quinidine on isolated rabbit atria.
Topics: Animals; Anti-Arrhythmia Agents; Heart Atria; Niacinamide; Quinidine; Rabbits | 1960 |
POTENTIATION OF THE ANTI-LEUKEMIC EFFECTS OF 2-AMINOTHIADIAZOLE BY ISONICOTINAMIDE AND DERIVATIVES.
Topics: Amides; Animals; Antineoplastic Agents; Isonicotinic Acids; Leukemia; Leukemia L1210; Leukemia, Experimental; Mice; Niacinamide; Pharmacology; Pyridines; Research; Thiadiazoles; Thiazoles | 1964 |
ELECTRIC MOMENT OF ISONICOTINAMIDE IN BENZENE AND DIOXANE SOLUTIONS.
Topics: Benzene; Chemical Phenomena; Chemistry, Physical; Dioxanes; Dioxins; Isonicotinic Acids; Niacin; Niacinamide; Research | 1965 |
Selectivity of effects of redox-active cobalt(III) complexes on tumor tissue.
Topics: Adenocarcinoma; Animals; Carcinoma, Lewis Lung; Cobalt; DNA Damage; Ethylenediamines; Female; Hypoxia; Ligands; Lipid Peroxidation; Malondialdehyde; Mammary Neoplasms, Experimental; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Niacin; Niacinamide; Oxidation-Reduction; Pentanones | 2004 |
Chemical activation of Sir2-dependent silencing by relief of nicotinamide inhibition.
Topics: Acetylation; Gene Expression Regulation, Fungal; Gene Silencing; Histone Deacetylase Inhibitors; Histone Deacetylases; NAD; Niacinamide; Nicotinamidase; Pentosyltransferases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 2; Sirtuins; Telomere; Transcription, Genetic | 2005 |
Catalase-peroxidase of Mycobacterium bovis BCG converts isoniazid to isonicotinamide, but not to isonicotinic acid: differentiation parameter between enzymes of Mycobacterium bovis BCG and Mycobacterium tuberculosis.
Topics: Bacterial Proteins; Isoniazid; Isonicotinic Acids; Molecular Weight; Mycobacterium bovis; Mycobacterium tuberculosis; Niacinamide; Peroxidases | 2006 |
Activation of Sirt1 decreases adipocyte formation during osteoblast differentiation of mesenchymal stem cells.
Topics: Adipocytes; Animals; Calcification, Physiologic; Cell Differentiation; Cell Line; Enzyme Inhibitors; Mesenchymal Stem Cells; Mice; Niacinamide; Osteoblasts; Osteogenesis; PPAR gamma; Rats; Rats, Wistar; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes | 2006 |
The amide rotational barrier in isonicotinamide: Dynamic NMR and ab initio studies.
Topics: Algorithms; Amides; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Structure; Niacinamide; Picolinic Acids; Quantum Theory; Rotation | 2005 |
A regenerable ruthenium tetraammine nitrosyl complex immobilized on a modified silica gel surface: preparation and studies of nitric oxide release and nitrite-to-NO conversion.
Topics: Amines; Niacinamide; Nitric Oxide; Nitrites; Organometallic Compounds; Ruthenium; Silica Gel; Silicon Dioxide | 2007 |
Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind beta-secretase in a N-terminal 10s-loop down conformation.
Topics: Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Baculoviridae; Biological Availability; Cells, Cultured; Enzyme Inhibitors; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Weight; Niacinamide; Rats; Structure-Activity Relationship | 2007 |
Molecular structure, vibrational spectra, quantum chemical calculations and photochemistry of picolinamide and isonicotinamide isolated in cryogenic inert matrixes and in the neat low-temperature solid phases.
Topics: Amides; Cold Temperature; Hydrogen Bonding; Molecular Structure; Niacinamide; Photochemistry; Picolinic Acids; Quantum Theory | 2008 |
Electrophile-induced dearomatizing spirocyclization of N-arylisonicotinamides: a route to spirocyclic piperidines.
Topics: Combinatorial Chemistry Techniques; Crystallography, X-Ray; Cyclization; Molecular Conformation; Niacinamide; Piperidines; Spiro Compounds | 2008 |
Chiral carboxylic acids and their effects on melting-point behaviour in co-crystals with isonicotinamide.
Topics: Calorimetry, Differential Scanning; Crystallization; Crystallography, X-Ray; Models, Molecular; Molecular Conformation; Niacinamide; Phenylbutyrates; Phenylpropionates; Stereoisomerism; Transition Temperature | 2008 |
Zero-, one- and two-dimensional hydrogen-bonded structures in the 1:1 proton-transfer compounds of 4,5-dichlorophthalic acid with the monocyclic heteroaromatic Lewis bases 2-aminopyrimidine, nicotinamide and isonicotinamide.
Topics: Hydrogen Bonding; Molecular Structure; Niacinamide; Phthalic Acids; Protons; Pyrimidines | 2009 |
Resveratrol inhibits proliferation and promotes apoptosis of osteosarcoma cells.
Topics: Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Growth Inhibitors; Humans; Niacinamide; Osteosarcoma; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes | 2009 |
Effect of soft segment crystallization and hard segment physical crosslink on shape memory function in antibacterial segmented polyurethane ionomers.
Topics: Anti-Bacterial Agents; Biocompatible Materials; Butylene Glycols; Cross-Linking Reagents; Crystallization; Hydrogen Bonding; Isocyanates; Materials Testing; Microbial Sensitivity Tests; Molecular Structure; Niacinamide; Nuclear Magnetic Resonance, Biomolecular; Polyesters; Polyurethanes; Spectroscopy, Fourier Transform Infrared; Temperature; Tensile Strength | 2009 |
Activation of SIRT1 by resveratrol represses transcription of the gene for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) by deacetylating hepatic nuclear factor 4alpha.
Topics: Acetylation; Animals; Base Sequence; Binding Sites; Cell Line; Cytosol; DNA; Enzyme Activation; Gene Expression Regulation, Enzymologic; Hepatocyte Nuclear Factor 4; Humans; Molecular Sequence Data; Niacinamide; Phosphoenolpyruvate Carboxykinase (GTP); Promoter Regions, Genetic; Resveratrol; Sirtuins; Stilbenes; Transcription Factor AP-1; Transcription, Genetic | 2009 |
Uncommon isonicotinamide supramolecular synthons in copper(II) complexes directed by nitrate and perchlorate anions.
Topics: Anions; Copper; Crystallography, X-Ray; Hydrogen Bonding; Models, Molecular; Niacinamide; Nitrates; Organometallic Compounds; Perchlorates | 2009 |
Structure elucidation of highly polar basic degradants by on-line hydrogen/deuterium exchange hydrophilic interaction chromatography coupled to tandem mass spectrometry.
Topics: Chromatography, Liquid; Deuterium Exchange Measurement; Deuterium Oxide; Isonicotinic Acids; Niacinamide; Pyridines; Tandem Mass Spectrometry; Temperature | 2010 |
Solubility, metastable zone width measurement and crystal growth of the 1:1 benzoic acid/isonicotinamide cocrystal in solutions of variable stoichiometry.
Topics: Benzoic Acid; Crystallization; Models, Molecular; Niacinamide; Powder Diffraction; Solubility; Solutions; X-Ray Diffraction | 2010 |
Antimycobacterial and antitumor activities of palladium(II) complexes containing isonicotinamide (isn): X-ray structure of trans-[Pd(N3)2(isn)(2)].
Topics: Animals; Antineoplastic Agents; Antitubercular Agents; Cell Line, Tumor; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Magnetic Resonance Spectroscopy; Mice; Mycobacterium tuberculosis; Niacinamide; Palladium; Spectrophotometry, Infrared | 2010 |
New polymorphs of isonicotinamide and nicotinamide.
Topics: Crystallization; Hydrogen Bonding; Models, Chemical; Molecular Structure; Niacinamide | 2011 |
Sir2 is induced by oxidative stress in a yeast model of Huntington disease and its activation reduces protein aggregation.
Topics: Humans; Huntington Disease; Mutant Proteins; Mutation; Niacinamide; Oxidative Stress; Peptides; Saccharomyces cerevisiae; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 2 | 2011 |
Antinociceptive and anti-inflammatory activities of nicotinamide and its isomers in different experimental models.
Topics: Amides; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Dipyrone; Edema; Female; Formaldehyde; Hot Temperature; Isomerism; Mice; Motor Activity; Niacinamide; Pain Measurement; Picolinic Acids; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Postural Balance; Rats; Rats, Wistar | 2011 |
Extending the supramolecular synthon based fragment approach (SBFA) for transferability of multipole charge density parameters to monofluorobenzoic acids and their cocrystals with isonicotinamide: importance of C-H···O, C-H···F, and F···F intermolecular r
Topics: Benzoates; Crystallization; Macromolecular Substances; Niacinamide; Quantum Theory | 2011 |
Cocrystals of quercetin with improved solubility and oral bioavailability.
Topics: Animals; Antioxidants; Caffeine; Calorimetry, Differential Scanning; Chemical Phenomena; Crystallography, X-Ray; Dietary Supplements; Half-Life; Intestinal Absorption; Male; Methanol; Molecular Conformation; Niacinamide; Powder Diffraction; Quercetin; Rats; Rats, Sprague-Dawley; Solubility; Spectroscopy, Fourier Transform Infrared; Theobromine | 2011 |
Mechanical stress-activated immune response genes via Sirtuin 1 expression in human periodontal ligament cells.
Topics: Acetylcysteine; Benzamides; Cell Line; Chemokines; Cytokines; Defensins; Extracellular Signal-Regulated MAP Kinases; Glutathione; Humans; JNK Mitogen-Activated Protein Kinases; Naphthols; NF-kappa B; Niacinamide; p38 Mitogen-Activated Protein Kinases; Periodontal Ligament; Protein Kinase C; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Resveratrol; RNA Interference; Signal Transduction; Sirtuin 1; Stilbenes; Stress, Mechanical; Toll-Like Receptors | 2012 |
Isonicotinamide enhances Sir2 protein-mediated silencing and longevity in yeast by raising intracellular NAD+ concentration.
Topics: DNA, Fungal; DNA, Ribosomal; Gene Silencing; Genetic Loci; NAD; Niacinamide; Nicotinamidase; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 2 | 2012 |
Unusual co-crystal of isonicotinamide: the structural landscape in crystal engineering.
Topics: Crystallization; Macromolecular Substances; Models, Chemical; Models, Molecular; Molecular Conformation; Nanostructures; Niacinamide | 2012 |
Surface-enhanced Raman scattering of picolinamide, nicotinamide, and isonicotinamide: unusual carboxamide deprotonation under adsorption on silver nanoparticles.
Topics: Adsorption; Amides; Colloids; Metal Nanoparticles; Niacinamide; Picolinic Acids; Protons; Silver; Spectrum Analysis, Raman | 2013 |
Spirocyclic dihydropyridines by electrophile-induced dearomatizing cyclization of N-alkenyl pyridinecarboxamides.
Topics: Acylation; Calcium Channel Blockers; Combinatorial Chemistry Techniques; Cyclization; Dihydropyridines; Molecular Structure; Niacinamide; Spiro Compounds | 2013 |
A 1:2 cocrystal of genistein with isonicotinamide: crystal structure and Hirshfeld surface analysis.
Topics: Chemistry, Pharmaceutical; Crystallography, X-Ray; Hydrogen Bonding; Molecular Structure; Niacinamide; Polyphenols | 2013 |
Protective effects of a nicotinamide derivative, isonicotinamide, against streptozotocin-induced β-cell damage and diabetes in mice.
Topics: Animals; Apoptosis; Cytoprotection; Diabetes Mellitus, Experimental; Diet, High-Fat; Hypoglycemic Agents; Insulin-Secreting Cells; Male; Mice; Mice, Inbred C57BL; Niacinamide; Sirtuin 1; Streptozocin | 2013 |
A novel strategy for pharmaceutical cocrystal generation without knowledge of stoichiometric ratio: myricetin cocrystals and a ternary phase diagram.
Topics: Caffeine; Calorimetry, Differential Scanning; Crystallization; Flavonoids; Microscopy, Electron, Scanning; Molecular Structure; Niacinamide; Nitriles; Phase Transition; Pyridines; Solubility; Spectroscopy, Fourier Transform Infrared; Surface Properties; Technology, Pharmaceutical; X-Ray Diffraction | 2015 |
Structures and spectroscopic characterization of calcium chloride-nicotinamide, -isonicotinamide, -picolinamide and praseodymium bromide-nicotinamide complexes.
Topics: Amides; Bromides; Calcium; Calcium Chloride; Carbon; Hydrogen Bonding; Ions; Ligands; Metals; Niacinamide; Nitrogen; Oxygen; Picolinic Acids; Praseodymium; Spectrophotometry; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; X-Ray Diffraction | 2015 |
Improving the dissolution and bioavailability of 6-mercaptopurine via co-crystallization with isonicotinamide.
Topics: Animals; Antimetabolites, Antineoplastic; Crystallization; Crystallography, X-Ray; Mercaptopurine; Models, Molecular; Niacinamide; Powder Diffraction; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; X-Ray Diffraction | 2015 |
Functional genomic analysis reveals overlapping and distinct features of chronologically long-lived yeast populations.
Topics: Biomarkers; Caloric Restriction; Culture Media, Conditioned; Gene Expression Profiling; Mutation; Niacinamide; Saccharomyces cerevisiae | 2015 |
A three-dimensional cadmium(II) coordination polymer with unequal homochiral double-stranded concentric helical chains.
Topics: Cadmium; Coordination Complexes; Crystallography, X-Ray; Hydrogen Bonding; Ligands; Molecular Structure; Niacinamide; Polymers | 2015 |
Synthesis, crystal structure, characterization and biological activity of 2,5-hexanedione bis(isonicotinylhydrazone) and N-(2,5-dimethyl-1H-pyrrol-1-yl)isonicotinamide complexes.
Topics: Anti-Bacterial Agents; Coordination Complexes; Crystallography, X-Ray; Hydrazones; Isonicotinic Acids; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Niacinamide; X-Ray Diffraction | 2015 |
Identification of New Cocrystal Systems with Stoichiometric Diversity of Salicylic Acid Using Thermal Methods.
Topics: Anti-Infective Agents; Benzamides; Calorimetry, Differential Scanning; Crystallization; Crystallography, X-Ray; Models, Molecular; Niacinamide; Powder Diffraction; Salicylic Acid; Temperature | 2016 |
Discovery of Isonicotinamides as Highly Selective, Brain Penetrable, and Orally Active Glycogen Synthase Kinase-3 Inhibitors.
Topics: Administration, Oral; Animals; Brain; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Discovery; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Molecular; Molecular Structure; Niacinamide; Protein Kinase Inhibitors; Structure-Activity Relationship | 2016 |
Synthesis, in vitro and in vivo pharmacological evaluation of serotoninergic ligands containing an isonicotinic nucleus.
Topics: Animals; Body Temperature; Humans; Ligands; Locomotion; Male; Mice; Niacinamide; Piperazine; Piperazines; Protein Binding; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A | 2016 |
Improving the solubility of dexlansoprazole by cocrystallization with isonicotinamide.
Topics: Calorimetry, Differential Scanning; Crystallization; Dexlansoprazole; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Niacinamide; Powder Diffraction; Proton Pump Inhibitors; Solubility; Solvents; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2016 |
Role of the Substrate Specificity-Defining Residues of Human SIRT5 in Modulating the Structural Stability and Inhibitory Features of the Enzyme.
Topics: Amino Acids; Biocatalysis; Calorimetry; Carbazoles; Catalytic Domain; Circular Dichroism; Enzyme Stability; Humans; Kinetics; Models, Molecular; Mutant Proteins; Mutation; Niacinamide; Protein Denaturation; Protein Structure, Secondary; Sirtuin 1; Sirtuins; Structure-Activity Relationship; Substrate Specificity; Temperature | 2016 |
Mechanochemical Synthesis of Pharmaceutical Cocrystal Suspensions via Hot Melt Extrusion: Feasibility Studies and Physicochemical Characterization.
Topics: Chemistry, Pharmaceutical; Drug Carriers; Feasibility Studies; Ibuprofen; Molecular Structure; Niacinamide; Suspensions | 2016 |
Drug-drug cocrystals of antituberculous 4-aminosalicylic acid: Screening, crystal structures, thermochemical and solubility studies.
Topics: Aminosalicylic Acid; Antitubercular Agents; Caffeine; Crystallization; Crystallography, X-Ray; Drug Stability; Isoniazid; Models, Molecular; Niacinamide; Powder Diffraction; Pyrazinamide; Solubility; Theophylline; X-Ray Diffraction | 2017 |
Synthesis of carbon-11-labeled isonicotinamides as new potential PET agents for imaging of GSK-3 enzyme in Alzheimer's disease.
Topics: Alzheimer Disease; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Glycogen Synthase Kinase 3; Humans; Isotope Labeling; Niacinamide; Positron-Emission Tomography; Radiopharmaceuticals; Solid Phase Extraction | 2017 |
Structural characterization and dissolution profile of mycophenolic acid cocrystals.
Topics: 2,2'-Dipyridyl; Calorimetry, Differential Scanning; Crystallization; Drug Liberation; Hydrogen Bonding; Hydrogen-Ion Concentration; Minoxidil; Models, Molecular; Molecular Structure; Mycophenolic Acid; Niacinamide; Powder Diffraction; Powders; Solubility; X-Ray Diffraction | 2017 |
Taming photo-induced oxidation degradation of dihydropyridine drugs through cocrystallization.
Topics: Calcium Channel Blockers; Crystallization; Dihydropyridines; Molecular Conformation; Niacinamide; Nifedipine; Oxidation-Reduction; Photochemical Processes; Thermodynamics | 2017 |
Engineering of pharmaceutical cocrystals in an excipient matrix: Spray drying versus hot melt extrusion.
Topics: Crystallization; Desiccation; Drug Compounding; Excipients; Hot Temperature; Ibuprofen; Mannitol; Niacinamide; Polyethylene Glycols; Polyvinyls; Pyrrolidines; Xylitol | 2018 |
Naringenin Cocrystals Prepared by Solution Crystallization Method for Improving Bioavailability and Anti-hyperlipidemia Effects.
Topics: Animals; Betaine; Biological Availability; Caffeine; Calorimetry, Differential Scanning; Crystallization; Flavanones; Hypolipidemic Agents; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Niacinamide; Proline; Rats; Rats, Sprague-Dawley; Solutions; Spectroscopy, Fourier Transform Infrared | 2019 |
Dissolution rate enhancement of new co-crystals of ezetimibe with maleic acid and isonicotinamide.
Topics: Anticholesteremic Agents; Calorimetry, Differential Scanning; Crystallization; Drug Combinations; Ezetimibe; Maleates; Microscopy, Electron, Scanning; Niacinamide; Powders; Spectrophotometry, Infrared; X-Ray Diffraction | 2019 |
Isonicotinamide-Based Compounds: From Cocrystal to Polymer.
Topics: Coordination Complexes; Crystallography, X-Ray; Models, Molecular; Molecular Structure; Niacinamide; Polymers | 2019 |
Cocrystals of diacerein: Towards the development of improved biopharmaceutical parameters.
Topics: Anthraquinones; Biological Availability; Biological Products; Calorimetry, Differential Scanning; Crystallization; Niacinamide; Powder Diffraction; Solubility; Spectroscopy, Fourier Transform Infrared; Theophylline; X-Ray Diffraction | 2020 |
Cocrystal formulations: A case study of topical formulations consisting of ferulic acid cocrystals.
Topics: Administration, Topical; Antioxidants; Chemistry, Pharmaceutical; Coumaric Acids; Crystallization; Delayed-Action Preparations; Drug Stability; Niacinamide; Organic Chemicals; Solubility; Urea; X-Ray Diffraction | 2020 |
Novel
Topics: Alzheimer Disease; Animals; Bipolar Disorder; Blood-Brain Barrier; Brain; Cell Line, Tumor; Diabetes Mellitus; Fluorine Radioisotopes; Glycogen Synthase Kinase 3 beta; Humans; Ligands; Neoplasms; Niacinamide; Positron-Emission Tomography; Radiopharmaceuticals; Rats | 2021 |
N-(3-cyano-1H-indol-5-yl)isonicotinamide and N-(3-cyano-1H-indol-5-yl)-1H-benzo[d]imidazole-5-carboxamide derivatives: Novel amide-based xanthine oxidase inhibitors.
Topics: Amides; Animals; Drug Design; Enzyme Inhibitors; Female; Hyperuricemia; Imidazoles; Male; Molecular Docking Simulation; Niacinamide; Rats, Sprague-Dawley; Structure-Activity Relationship; Xanthine Oxidase | 2021 |
Pressure-induced superelastic behaviour of isonicotinamide.
Topics: Elasticity; Hydrogen Bonding; Models, Chemical; Niacinamide; Phase Transition; Pressure | 2021 |
Temperature-Dependent Terahertz Spectra of Isonicotinamide in the Form I Studied Using the Quasi-Harmonic Approximation.
Topics: Molecular Conformation; Niacinamide; Temperature; Terahertz Spectroscopy; Vibration | 2022 |
The fingerprints of nifedipine/isonicotinamide cocrystal polymorph studied by terahertz time-domain spectroscopy.
Topics: Niacinamide; Nifedipine; Pharmaceutical Preparations; Terahertz Spectroscopy; Vibration | 2022 |
The SRPK inhibitor N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl) isonicotinamide (SRPIN340) increases the immune response against metastatic melanoma in mice.
Topics: Animals; Humans; Immunity; Melanoma; Mice; Niacinamide; Piperidines; Protein Serine-Threonine Kinases; Skin Neoplasms; Tumor Microenvironment | 2022 |