niacinamide and isomethyleugenol

niacinamide has been researched along with isomethyleugenol in 79 studies

Research

Studies (79)

TimeframeStudies, this research(%)All Research%
pre-199049 (62.03)18.7374
1990's8 (10.13)18.2507
2000's4 (5.06)29.6817
2010's15 (18.99)24.3611
2020's3 (3.80)2.80

Authors

AuthorsStudies
Mys'ko, GN1
Arndt, G; Christ, W; Schulze, G1
Matthysse, S1
Johansson-Brittebo, E; Tjälve, H1
Biswal, N; Sharma, S1
Buttrum, S; Green, S; Molloy, H; Pall, H; Steventon, G; Sturman, S; Waring, R; Williams, A1
Cox, R; Kuykendall, JR1
Henning, SM; McKee, RW; Swendseid, ME1
Hanski, C; Lawley, PD1
Fukui, S; Hirayama, T; Nohara, M; Uda, K; Yoshida, K1
Bickel, MH; Willi, P1
De Vincentiis, E; Papa, B; Tardio, B1
Brooke, D; Guttman, DE1
Zelinskiĭ, VG1
Borghesi, E; Gentili, C1
Dewaide, JH; Henderson, PT1
Bradshaw, RA; Deranleau, DA; Schwyzer, R1
Chagovets, RV; Shmat'ko, TM1
Jameson, D; Josephs, JA; Parker, CM; Sprince, H1
Ellerbrook, RC; Purdy, MB1
Kanig, K1
Bickel, MH; Gigon, PL1
Coubeils, JL; Courrière, P; Pullman, B1
Gholson, RK; Lee, YC; McKenzie, RM; Raica, N1
Holmes, LG; Robbins, FM1
Hirsch, GH1
Chaykin, S; Collins, PB; Higgins, TJ; Watson, JG1
Nath, MC; Nath, N; Sivakumar, B1
Bell, RR; Blanchard, CA; Haskell, BE1
Hayashi, Y1
Burkhalter, A; MacGregor, JT1
Casida, JE; Roger, JC; Upshall, DG1
Cohen, BS; Estabrook, RW2
Ackermann, E1
Akhtar, M; Bloxham, DP; Wilton, DC1
Blumenstein, M; Raftery, MA1
Hoshino, J; Kröger, H; Kühne, U1
Hoshino, J; Kröger, H; Schlüter, U1
Hoshino, J; Kröger, H; Seifert, R1
Ciusa, W1
Huang, SS; Pontzer, NJ; Shaikh, B1
Bennett, RA; Pegg, AE1
Boyle, JM; Durrant, LG; Margison, GP1
Cox, R1
Henning, SM; Jacob, RA; Pianalto, FS; Swendseid, ME; Zhang, JZ1
Boselli, L; Budillon, G; Capuano, G; Cuomo, R; Dattilo, M; Pumpo, R1
Buttrum, S; Green, S; Molloy, H; Pall, HS; Steventon, GB; Waring, RH; Williams, AC1
Budillon, G; Capuano, G; Cuomo, R; Pumpo, R; Sarnelli, G1
Kozak, CA; Otterness, DM; Weinshilboum, RM; Yan, L1
Bodennec, J; Brichon, G; Koul, O; Portoukalian, J; Zwingelstein, G1
Aoyama, K; Fukushima, S; Hayase, N; Kobayashi, S; Matsubara, K; Ohta, S; Okada, K; Satomi, M; Shimizu, K; Shiono, H; Uezono, T; Yamaguchi, S1
FATTERPAKER, P; MARFATIA, U; SREENIVASAN, A1
AUDETTE, RC; WORTHEN, LR; YOUNGKEN, HW1
Chow, BF; Ranke, B; Ranke, E1
CANTONI, GL1
BARENSE, D; BETHELL, FH; SWENDSEID, ME1
Ramsden, DB; Williams, AC2
Holman, WI; Wiegand, C1
Adsool, VA; Pansare, SV1
Gong, XJ; Guo, M; Jing, LX; Li, D; Lun, YZ; Sun, SX; Sun, WP; Xiao, FC; Zhang, LB; Zhou, SS1
Fukushima, T; Hayakawa, T; Kakamu, T; Kanda, H; Mori, Y; Sugawara, A; Tsuboi, S; Tsuji, M1
Prombona, A; Sekeri-Pataryas, KE; Sourlingas, TG; Xydous, M1
Cravatt, BF; Ulanovskaya, OA; Zuhl, AM1
Chan, PK; Chapman-Rothe, N; Festenstein, R; Giunti, P; Grosan, C; Khadayate, S; Law, PP; Mauri, M; Pook, M; Torres, R; Yandim, C1
Birringer, M; Cohen, HY; Groth, M; Guthke, R; Heiland, I; Hoppe, T; Kanfi, Y; Kuhlow, D; Mansfeld, J; Pfeiffer, AF; Platzer, M; Price, NL; Priebe, S; Ristow, M; Schmeisser, K; Schmeisser, S; Schuster, S; Segref, A; Sinclair, DA; Weimer, S; Zarse, K1
Cao, YJ; Fisniku, O; Nagasaka, Y; Nakada, N; Oda, K; Sawamoto, T; Sohda, KY1
Battle, SL; Bielas, JH; Blau, CA; Detraux, D; Devi, A; Ericson, NG; Ferreccio, A; Fiehn, O; Fischer, KA; Gu, H; Hawkins, RD; Hesson, J; Hockenbery, D; Margaretha, L; Margineantu, D; Margolin, AA; Mathieu, J; Moon, RT; Raftery, D; Robitaille, AM; Ruohola-Baker, H; Showalter, M; Sperber, H; Valensisi, C; Wang, Y; Ware, CB; Xu, Z1
Chen, NN; Guo, M; Li, D; Sun, WP; Zhai, MZ; Zhou, SS; Zhou, Y1
Athanasou, N; Bountra, C; Brennan, PE; Burgess-Brown, NA; Davies, F; England, KS; Fedorov, O; Hatch, SB; Hookway, ES; Johansson, C; Kawamura, A; La Thangue, NB; Morgan, G; Müller, S; Munro, S; Nowak, RP; Nuzzi, A; Oppermann, U; Pawlyn, C; Ruda, GF; Savitsky, P; Schofield, CJ; Strain-Damerell, C; Szykowska, A; Tumber, A; Velupillai, S; Wu, N; Yapp, C1
Chen, T; Cui, M; Cui, Y; Ge, C; Huo, Q; Li, H; Li, J; Sun, J; Tian, H; Xie, H; Yao, M; Zhao, F1
Miller, L; Nemmara, VV; Nguyen, SH; Salinger, AJ; Thompson, PR; Tilvawala, R; Weerapana, E1
Loring, HS; Thompson, PR1
Albrecht, LV; Bui, MH; De Robertis, EM1
Brown, TM; Daze, KD; Dev, A; Douglas, SF; Hirsch, AKH; Hof, F; Milosevich, N; Monjas, L; Simhadri, C; Wulff, JE1
El-Sheikh, M; Ko, J; Kong, IK; Mesalam, AA; Song, SH1
Dabelić, N; Fröbe, A; Mojzeš, A; Novak Kujundžić, R; Prpić, M; Tomljanović, M; Trošelj, KG; Đaković, N1
Barrows, RD; Galkin, MV; Golanov, AV; Jeffries, DE; Jin, S; Li, F; Li, X; Luan, H; Ma, Z; Ni, J; Rongshan, Y; Sergeeva, NA; Serova, NK; Shair, MD; Song, H; Tukachinsky, H; Vishe, M; Wen, L; Ying, C; Zagirov, RI; Zhang, R; Zhang, S; Zheng, SL1

Reviews

3 review(s) available for niacinamide and isomethyleugenol

ArticleYear
Capacity of stressed humans under mega dosages of nicotinic acid to synthesize methylated compounds.
    Diseases of the nervous system, 1970, Volume: 31, Issue:3

    Topics: Catecholamines; Creatinine; Epinephrine; Humans; Methionine; Methylation; Niacinamide; Nicotinic Acids; Norepinephrine; Stress, Psychological; Time Factors

1970
Autotoxicity, methylation and a road to the prevention of Parkinson's disease.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2005, Volume: 12, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Dopamine Agents; Humans; Methylation; Niacinamide; Parkinson Disease; Parkinson Disease, Secondary; Risk Factors; S-Adenosylmethionine

2005
Nicotinamide N-Methyltransferase in Acquisition of Stem Cell Properties and Therapy Resistance in Cancer.
    International journal of molecular sciences, 2021, May-26, Volume: 22, Issue:11

    Topics: Humans; Methylation; NAD; Neoplasm Proteins; Neoplasms; Neoplastic Stem Cells; Niacinamide; Nicotinamide N-Methyltransferase

2021

Trials

2 trial(s) available for niacinamide and isomethyleugenol

ArticleYear
In vivo methylation capacity is not impaired in healthy men during short-term dietary folate and methyl group restriction.
    The Journal of nutrition, 1995, Volume: 125, Issue:6

    Topics: Administration, Oral; Adult; Carnitine; Choline; Choline Deficiency; Creatinine; Cross-Over Studies; Diet; Folic Acid; Folic Acid Deficiency; Food, Fortified; Humans; Male; Methionine; Methylation; Middle Aged; Niacinamide; Time Factors

1995
N-methylation ability for azaheterocyclic amines is higher in Parkinson's disease: nicotinamide loading test.
    Journal of neural transmission (Vienna, Austria : 1996), 2000, Volume: 107, Issue:8-9

    Topics: Aged; Aging; Aldehyde Oxidase; Aldehyde Oxidoreductases; Brain; Carbolines; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Female; Humans; Isoquinolines; Male; Methylation; Middle Aged; Niacinamide; Parkinson Disease

2000

Other Studies

74 other study(ies) available for niacinamide and isomethyleugenol

ArticleYear
[Several indices of the methylation process in schizophrenic patients].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1977, Volume: 77, Issue:7

    Topics: Adult; Antipsychotic Agents; Automatism; Catechol O-Methyltransferase; Depression; Female; Hallucinations; Humans; Isoproterenol; Male; Methylation; Middle Aged; Niacinamide; Schizophrenia; Schizophrenia, Catatonic; Schizophrenia, Paranoid; Syndrome

1977
Separation behaviour of nicotinamide and thionicotinamide derivatives on Dowex 1-X8.
    Journal of chromatography, 1975, Mar-26, Volume: 106, Issue:2

    Topics: Buffers; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Chromatography, Affinity; Glass; Ion Exchange Resins; Methods; Methylation; Methyltransferases; Niacinamide; Polystyrenes

1975
On lowering S-adenosylmethionine.
    Monographien aus dem Gesamtgebiete der Psychiatrie, 1978, Volume: 18

    Topics: Animals; Levodopa; Liver; Methylation; Methyltransferases; Niacinamide; Norepinephrine; Rats; S-Adenosylmethionine

1978
The fate of [14C]streptozotocin in nicotinamide-pretreated mice: observations on pancreatic islet radioactivity and urinary N1-methyl-14C]nicotinamide-excretion.
    Cancer letters, 1979, Volume: 8, Issue:2

    Topics: Animals; Carbon Radioisotopes; Female; Islets of Langerhans; Methylation; Mice; Niacinamide; Streptozocin; Tissue Distribution

1979
Studies on the in vivo methylation of replicating herpes simplex virus type 1 DNA.
    Virology, 1977, Oct-15, Volume: 82, Issue:2

    Topics: Animals; Culture Techniques; DNA Replication; DNA, Viral; Methylation; Niacinamide; Rabbits; Simplexvirus; Virus Replication

1977
N-methylation of pyridines in Parkinson's disease.
    Lancet (London, England), 1991, Jul-13, Volume: 338, Issue:8759

    Topics: Humans; Methylation; Middle Aged; Niacinamide; Parkinson Disease

1991
2-Aminobenzamide, an inhibitor of ADP-ribosylation, antagonizes induced DNA hypomethylation during differentiation of murine Friend erythroleukemia cells by N'-methylnicotinamide.
    Differentiation; research in biological diversity, 1990, Volume: 44, Issue:1

    Topics: Adenosine Diphosphate Ribose; Animals; Cell Differentiation; Cell Line; DNA, Neoplasm; Friend murine leukemia virus; Heme; Leukemia, Erythroblastic, Acute; Methylation; Mice; Niacinamide; ortho-Aminobenzoates

1990
Hepatic content of S-adenosylmethionine, S-adenosylhomocysteine and glutathione in rats receiving treatments modulating methyl donor availability.
    The Journal of nutrition, 1989, Volume: 119, Issue:10

    Topics: Animals; Biomarkers; Choline Deficiency; Cysteine; Diet; Fatty Liver; Folic Acid Deficiency; Glutathione; Homocysteine; Lipids; Liver; Male; Methionine; Methylation; Niacinamide; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine

1989
Urinary excretion of 3-methyladenine and 1-methylnicotinamide by rats, following administration of [methyl-14C]methyl methanesulphonate and comparison with administration of [14C]methionine or formate.
    Chemico-biological interactions, 1985, Volume: 55, Issue:1-2

    Topics: Adenine; Alkylation; Animals; Chromatography, Ion Exchange; Female; Formates; Methionine; Methyl Methanesulfonate; Methylation; Niacinamide; Rats

1985
High-performance liquid chromatographic determination of N1-alkylnicotinamide in urine.
    Analytical biochemistry, 1985, May-15, Volume: 147, Issue:1

    Topics: Adult; Alkylation; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Humans; Male; Methylation; Middle Aged; NAD; NADP; Naphthyridines; Niacinamide; Spectrometry, Fluorescence

1985
Liver metabolic reactions: tertiary amine N-dealkylation, tertiary amine N-oxidation, N-oxide reduction, and N-oxide N-dealkylation. II. N,N-dimethylaniline.
    Archives of biochemistry and biophysics, 1973, Volume: 156, Issue:2

    Topics: Acetates; Aniline Compounds; Animals; Calcium; Depression, Chemical; Edetic Acid; Formaldehyde; Glycols; Kinetics; Magnesium; Male; Methylation; Microsomes, Liver; NADP; Niacinamide; Nitrogen Oxides; Oxidation-Reduction; Phenobarbital; Proadifen; Rats; Species Specificity; Stimulation, Chemical; Sulfhydryl Reagents; Swine

1973
[Several aspects of hepatic function in the aged surgical patient].
    Giornale italiano di chirurgia, 1966, Volume: 22, Issue:4

    Topics: Aged; Humans; Liver; Liver Function Tests; Methionine; Methylation; Niacinamide; Surgical Procedures, Operative

1966
Salt effects in the spectrophotometric examination of a complex of N'-methylnicotinamide cation.
    Journal of pharmaceutical sciences, 1968, Volume: 57, Issue:7

    Topics: Chemical Phenomena; Chemistry; Methylation; Niacinamide; Salts; Spectrophotometry

1968
[Study of nicotinamide methylation in liver sections of rats irradiated with x-rays].
    Ukrains'kyi biokhimichnyi zhurnal, 1966, Volume: 38, Issue:5

    Topics: Adenosine Triphosphate; Animals; Glutathione; Liver; Methylation; Niacinamide; Radiation Effects; Rats; Stimulation, Chemical; Time Factors

1966
[Remarks on the level of transmethylases in schizophrenic patients. In vitro assays].
    Bollettino della Societa italiana di biologia sperimentale, 1967, Nov-30, Volume: 43, Issue:22

    Topics: Betaine; Humans; In Vitro Techniques; Methylation; Niacinamide; Schizophrenia

1967
Hepatic N-demethylation of aminopyrine in rat and trout.
    Biochemical pharmacology, 1968, Volume: 17, Issue:9

    Topics: Aminopyrine; Animals; Hydrogen-Ion Concentration; Liver; Methods; Methylation; Niacinamide; Rats; Salmonidae; Semicarbazides; Species Specificity; Temperature; Time Factors

1968
The use of n-methylnicotin amide chloride as a conformational probe for chicken egg-white lysozyme.
    Proceedings of the National Academy of Sciences of the United States of America, 1969, Volume: 63, Issue:3

    Topics: Animals; Chlorides; Methylation; Muramidase; Niacinamide; Ovalbumin; Spectrophotometry

1969
[Changes in methionine-S35 metabolism in liver of albino rats under the effect of nicotinic acid and nicotonamide and peculiarities of nicotinamide methylation].
    Ukrains'kyi biokhimichnyi zhurnal, 1969, Volume: 41, Issue:1

    Topics: Animals; Chromatography; Glutathione; Liver; Methionine; Methylation; Niacinamide; Nucleosides; Solubility; Stimulation, Chemical; Sulfur Isotopes; Water

1969
Experimental alteration of tryptophan metabolism by methionine: neuropharmacologic implications.
    International journal of neuropharmacology, 1969, Volume: 8, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Body Weight; Creatinine; Deficiency Diseases; Diet; Glycine; Indoleacetic Acids; Male; Methionine; Methylation; Niacinamide; Nicotinic Acids; Pyridoxine; Rats; Tryptophan; Xanthurenates

1969
[Biochemical mechanism of action of nicotinic acid, nicotinamide, methionine and D-penicillamine in treatment of psychoses].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:7

    Topics: Amines; Amino Acids; Biochemical Phenomena; Biochemistry; Humans; Methionine; Methylation; Niacinamide; Nicotinic Acids; Penicillamine; Psychopharmacology; Psychotic Disorders; Serotonin; Sulfhydryl Compounds; Tryptamines; Tryptophan

1970
Drug metabolism by hepatic microsomes from phenobarbital-treated or starved male and female rats in the presence of inhibitors.
    Life sciences. Pt. 2: Biochemistry, general and molecular biology, 1971, Feb-08, Volume: 10, Issue:3

    Topics: Aminopyrine; Aniline Compounds; Animals; Cytochromes; Female; Hexobarbital; Liver; Male; Methylation; Microsomes, Liver; Morphinans; Niacinamide; Organ Size; Phenobarbital; Proadifen; Rats; Starvation

1971
A molecular orbital study of the conformational properties of nicotinamides.
    Biochemical and biophysical research communications, 1971, Volume: 44, Issue:5

    Topics: Chemical Phenomena; Chemistry, Physical; Methylation; Models, Chemical; Models, Structural; Niacinamide; Oxidation-Reduction; Ribonucleosides; Thermodynamics

1971
A comparative study of the metabolism of nicotinamide and nicotinic acid in normal and germ-free rats.
    Biochimica et biophysica acta, 1972, Mar-30, Volume: 264, Issue:1

    Topics: Animals; Carbon Dioxide; Carbon Isotopes; Chromatography, Thin Layer; Electrophoresis, Paper; Germ-Free Life; Intestines; Male; Methylation; Niacinamide; Nicotinic Acids; Pyridones; Rats

1972
Binding of N-methyl nicotinamide chloride by tryptophan residues of -lactalbumin.
    The Journal of biological chemistry, 1972, May-25, Volume: 247, Issue:10

    Topics: Acetates; Albumins; Energy Transfer; Ethanol; Hydrogen-Ion Concentration; Methylation; Muramidase; Niacinamide; Protein Binding; Protein Denaturation; Spectrophotometry; Tryptophan; Ultraviolet Rays

1972
Stimulation of renal organic base transport by uranyl nitrate.
    Canadian journal of physiology and pharmacology, 1972, Volume: 50, Issue:6

    Topics: Aminohippuric Acids; Animals; Biological Transport; Body Weight; Carbon Isotopes; Kidney; Kinetics; Male; Methylation; Necrosis; Niacinamide; Nitrates; Organ Size; Potassium Chloride; Rats; Stimulation, Chemical; Tetraethylammonium Compounds; Uranium

1972
The mouse liver aldehyde oxidase locus (Aox).
    Biochemical genetics, 1972, Volume: 6, Issue:2

    Topics: Adrenal Glands; Adrenalectomy; Aldehyde Oxidoreductases; Animals; Carbon Isotopes; Chromatography, Paper; Female; Genetic Linkage; Kinetics; Lethal Dose 50; Liver; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Niacinamide; Recombination, Genetic

1972
Effect of ketone bodies and ACTH on the transmethylation reaction (S-adenosylmethionine dependent system) in rats. II.
    Enzymologia, 1969, Oct-31, Volume: 37, Issue:4

    Topics: Acetoacetates; Adrenocorticotropic Hormone; Animals; Enzyme Inhibitors; Growth; Hydroxybutyrates; In Vitro Techniques; Injections, Intraperitoneal; Ketone Bodies; Liver; Methionine; Methylation; Niacinamide; Rats

1969
Metabolism of vitamin B 6 in the I-strain mouse. II. Oxidation of pyridoxal.
    Archives of biochemistry and biophysics, 1971, Volume: 147, Issue:2

    Topics: Acetone; Aldehydes; Ammonium Sulfate; Animals; Brain; Chemical Precipitation; Diet; Drug Stability; Hot Temperature; Hydrogen-Ion Concentration; Isonicotinic Acids; Kinetics; Liver; Male; Methylation; Mice; Mice, Inbred Strains; Niacinamide; Oxidoreductases; Phosphoric Monoester Hydrolases; Picolines; Pyridoxal Phosphate; Pyridoxine; Species Specificity; Vitamin B 6 Deficiency

1971
[Experimental pancreatic tumor].
    Nihon rinsho. Japanese journal of clinical medicine, 1972, Volume: 30, Issue:1

    Topics: Adenoma, Islet Cell; Animals; Carcinogens; Cyclic N-Oxides; Dogs; Guinea Pigs; Methylation; Neoplasms, Experimental; Niacinamide; Nitrosourea Compounds; Pancreatic Neoplasms; Quinolines; Rats; Streptozocin

1972
Biliary excretion of nicotinamide riboside. A possible role in the regulation of hepatic pyridine nucleotide dynamics.
    Biochemical pharmacology, 1973, Nov-01, Volume: 22, Issue:21

    Topics: Animals; Bile; Carbon Radioisotopes; Chromatography, Gel; Chromatography, Paper; Electrophoresis, Paper; Female; Fluorometry; Freeze Drying; Liver; Methylation; NAD; Niacinamide; Nicotinamide Mononucleotide; Nicotinic Acids; Rats; Ribonucleosides; Time Factors

1973
Structure--activity and metabolism studies on organophosphate teratogens and their alleviating agents in developing hen eggs with special emphasis on Bidrin.
    Biochemical pharmacology, 1969, Volume: 18, Issue:2

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Butyrates; Chick Embryo; Cholinesterase Inhibitors; Methylation; NAD; NADP; Niacinamide; Nicotinic Acids; Nucleotides; Phosphoric Acids; Phosphorus Isotopes; Time Factors

1969
Microsomal electron transport reactions. I. Interaction of reduced triphosphopyridine nucleotide during the oxidative demethylation of aminopyrine and cytochrome b 5 reduction.
    Archives of biochemistry and biophysics, 1971, Volume: 143, Issue:1

    Topics: Aminopyrine; Animals; Cytochromes; Dealkylation; Electron Transport; Fasting; Fluorometry; Formaldehyde; Isocitrate Dehydrogenase; Kinetics; Male; Methylation; Microsomes, Liver; NADP; Niacinamide; Oxidation-Reduction; Oxidoreductases; Rabbits; Spectrophotometry; Ultraviolet Rays

1971
Microsomal electron transport reactions. II. The use of reduced triphosphopyridine nucleotide and-or reduced diphosphopyridine nucleotide for the oxidative N-demethylation of aminopyrine and other drug substrates.
    Archives of biochemistry and biophysics, 1971, Volume: 143, Issue:1

    Topics: Aminopyrine; Animals; Codeine; Dealkylation; Electron Transport; Fasting; Formaldehyde; Kinetics; Male; Methylation; Microsomes; Microsomes, Liver; Morphinans; NAD; NADP; Niacinamide; Oxidation-Reduction; Oxidoreductases; Rabbits

1971
[Demethylation of aminophenazone and codeine in human liver. An investigation of microsomal electron transport].
    Biochemical pharmacology, 1970, Volume: 19, Issue:6

    Topics: Aminopyrine; Animals; Codeine; Cyanides; Cytochromes; Dealkylation; Electron Spin Resonance Spectroscopy; Electron Transport; Female; Glucosephosphate Dehydrogenase; Half-Life; Humans; Kinetics; Lysosomes; Male; Mathematics; Methylation; Microsomes, Liver; Middle Aged; Mitochondria, Liver; NADP; Niacinamide; Oxidoreductases; Pentosephosphates; Phosphogluconate Dehydrogenase; Proadifen; Rats; Sex Factors; Species Specificity; Spectrophotometry

1970
Studies on the mechanism and regulation of C-4 demethylation in cholesterol biosynthesis. The role of adenosine 3':5'-cyclic monophosphate.
    The Biochemical journal, 1971, Volume: 125, Issue:2

    Topics: Aerobiosis; Anaerobiosis; Animals; Carboxylic Acids; Cholestanes; Cholesterol; Cyclic AMP; Glutamate Dehydrogenase; Glutamates; Glutarates; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Ketosteroids; Methods; Methylation; Microsomes, Liver; NAD; NADP; Niacinamide; Rats; Sterols; Tritium

1971
31 P and 13 C nuclear magnetic resonance studies of nicotinamide-adenine dinucleotide and related compounds.
    Biochemistry, 1972, Apr-25, Volume: 11, Issue:9

    Topics: Acetates; Adenine Nucleotides; Adenosine Monophosphate; Alcohol Oxidoreductases; Carbon Isotopes; Carbonates; Chemical Phenomena; Chemistry; Hydrogen-Ion Concentration; Isotope Labeling; Magnetic Resonance Spectroscopy; Methylation; N-Glycosyl Hydrolases; NAD; NADP; Niacinamide; Nicotinic Acids; Nucleoside Diphosphate Sugars; Nucleotides; Oxidation-Reduction; Phosphoric Diester Hydrolases; Phosphorus; Pyridines; Ribose

1972
Methylation of nicotinamide in rat liver cytosol and its correlation with hepatocellular proliferation.
    Biochimica et biophysica acta, 1982, Dec-17, Volume: 719, Issue:3

    Topics: Animals; Cytosol; Kinetics; Liver; Liver Regeneration; Male; Methylation; Methyltransferases; Niacinamide; Nicotinamide N-Methyltransferase; Rats; Rats, Inbred Strains; Thioacetamide

1982
Nicotinamide methylation and its relation to NAD synthesis in rat liver tissue culture. Biochemical basis for the physiological activities of 1-methylnicotinamide.
    Biochimica et biophysica acta, 1984, Sep-28, Volume: 801, Issue:2

    Topics: Adenosine Triphosphate; Animals; Carbon Radioisotopes; Cells, Cultured; Cytosol; Female; In Vitro Techniques; Kinetics; Liver; Methylation; NAD; Niacinamide; Oxidation-Reduction; Rats; Rats, Inbred Strains

1984
Nicotinamide methylation. Tissue distribution, developmental and neoplastic changes.
    Biochimica et biophysica acta, 1984, Sep-28, Volume: 801, Issue:2

    Topics: Aging; Animals; Brain; Carcinoma, Ehrlich Tumor; Cell Line; Female; Kidney; Liver; Liver Neoplasms, Experimental; Methylation; Methyltransferases; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Niacinamide; Nicotinamide N-Methyltransferase; Rats; Rats, Inbred Strains; Sarcoma 180; Sarcoma, Yoshida; Tissue Distribution

1984
[Donors and receptors of biologically labile methyl groups: characterization with a nicotinamide-trigonelline system].
    Acta vitaminologica et enzymologica, 1984, Volume: 6, Issue:4

    Topics: Alkaloids; Animals; Cattle; Lens, Crystalline; Methylation; Niacinamide; Thiamine

1984
Urinary excretion of methylated purines and 1-methyl-nicotinamide following administration of methylating carcinogens.
    Chemico-biological interactions, 1980, Volume: 30, Issue:2

    Topics: 1,2-Dimethylhydrazine; Adenine; Alkylating Agents; Animals; Carcinogens; Dimethylhydrazines; Dimethylnitrosamine; Guanine; Male; Methyl Methanesulfonate; Methylation; Methylnitronitrosoguanidine; Niacinamide; Rats

1980
Alkylation of DNA in rat tissues following administration of streptozotocin.
    Cancer research, 1981, Volume: 41, Issue:7

    Topics: Animals; Carcinogens; Chromatography, High Pressure Liquid; DNA; Female; Injections, Intravenous; Intestinal Mucosa; Methylation; Methylnitrosourea; Niacinamide; Pancreas; Purines; Rats; Streptozocin

1981
Effects of 5-methylnicotinamide on mouse L1210 cells exposed to N-methyl-N-nitrosourea: mutation induction, formation and removal of methylation products in DNA, and unscheduled DNA synthesis.
    Carcinogenesis, 1981, Volume: 2, Issue:10

    Topics: Animals; Cells, Cultured; DNA Repair; DNA, Neoplasm; Leukemia L1210; Methylation; Methylnitrosourea; Mice; Mutagens; Niacinamide; Nitrosourea Compounds; Purines

1981
Ethionine alters the urinary excretion of N1-methylnicotinamide.
    Cancer letters, 1981, Volume: 14, Issue:2

    Topics: Animals; Ethionine; Liver; Male; Methylation; Methyltransferases; NAD; Niacinamide; Rats; Time Factors

1981
Nicotinamide methylation in patients with cirrhosis.
    Journal of hepatology, 1994, Volume: 20, Issue:1

    Topics: Female; Humans; Liver; Liver Cirrhosis; Male; Methylation; Methyltransferases; Middle Aged; Niacinamide; Nicotinamide N-Methyltransferase

1994
N-methylation of pyridines and Parkinson's disease.
    Advances in neurology, 1993, Volume: 60

    Topics: Humans; Methylation; Methyltransferases; Niacinamide; Parkinson Disease; Pyridines; Pyridones

1993
Nicotinamide methylation and hepatic energy reserve: a study by liver perfusion in vitro.
    Journal of hepatology, 1995, Volume: 23, Issue:4

    Topics: Adenosine Triphosphate; Animals; In Vitro Techniques; Liver; Methylation; NAD; Niacinamide; Perfusion; Rats; Rats, Sprague-Dawley

1995
Mouse nicotinamide N-methyltransferase gene: molecular cloning, structural characterization, and chromosomal localization.
    DNA and cell biology, 1998, Volume: 17, Issue:8

    Topics: Amino Acid Sequence; Animals; Base Sequence; Chromosome Mapping; Cloning, Molecular; Liver; Methylation; Methyltransferases; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Molecular Sequence Data; Niacinamide; Nicotinamide N-Methyltransferase; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Species Specificity

1998
Phytosphingosine biosynthesis differs from sphingosine in fish leukocytes and involves a transfer of methyl groups from [3H-methyl]methionine precursor.
    Biochemical and biophysical research communications, 1998, Sep-08, Volume: 250, Issue:1

    Topics: Animals; Bass; Chromatography, Gas; Chromatography, Thin Layer; Folic Acid; Leukocytes; Methylation; Niacinamide; Sphingosine; Tritium

1998
Rôle of folic acid and vitamin B12 in transmethylations. III. An influence of folic acid on the methylation of nicotinamide.
    The Indian journal of medical research, 1955, Volume: 43, Issue:2

    Topics: Folic Acid; Humans; Methylation; Niacin; Niacinamide; Nicotinic Acids; Vitamin B 12; Vitamin B Complex

1955
ENZYMATIC METHYLATION ON NICOTINAMIDE BY CLAVICEPS PURPUREA.
    Journal of pharmaceutical sciences, 1964, Volume: 53

    Topics: Alkylation; Ascomycota; Claviceps; Enzymes; Metabolism; Methylation; Niacinamide; Research; Serotonin; Tryptamines; Tyramine

1964
Methylation of nicotinamide in vitamin B12- and vitamin B6-deficient rats.
    The Journal of nutrition, 1962, Volume: 76, Issue:4

    Topics: Animals; Methylation; Niacin; Niacinamide; Nicotinic Acids; Rats; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency; Vitamin B Complex

1962
Methylation of nicotinamide with soluble enzyme system from rat liver.
    The Journal of biological chemistry, 1951, Volume: 189, Issue:1

    Topics: Animals; Liver; Methylation; Niacin; Niacinamide; Rats

1951
Methylation of nicotinamide in patients with pernicious anemia.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1951, Volume: 78, Issue:1

    Topics: Anemia; Anemia, Pernicious; Humans; Methylation; Niacin; Niacinamide; Tracheophyta

1951
Nicotinamide homeostasis: a xenobiotic pathway that is key to development and degenerative diseases.
    Medical hypotheses, 2005, Volume: 65, Issue:2

    Topics: Animals; Choline; Embryonic Development; Epigenesis, Genetic; Evolution, Molecular; Homeostasis; Humans; Methylation; Models, Theoretical; Niacinamide; Parkinson Disease; Xenobiotics

2005
The chemical conversion of nicotinic acid and nicotinamide to derivatives of N-methyl-2-pyridone by methylation and oxidation.
    The Biochemical journal, 1948, Volume: 43, Issue:3

    Topics: Methylation; Niacin; Niacinamide; Nicotinic Acids; Oxidation-Reduction; Pyridones

1948
Enantioselective synthesis of functionalized medium-sized oxacycles.
    Organic letters, 2006, Dec-07, Volume: 8, Issue:25

    Topics: Cyclization; Electrons; Heterocyclic Compounds, 1-Ring; Indicators and Reagents; Lactams; Lithium; Methylation; Niacin; Niacinamide; Piperidines; Pyridines

2006
Excess nicotinamide inhibits methylation-mediated degradation of catecholamines in normotensives and hypertensives.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2012, Volume: 35, Issue:2

    Topics: Adult; Betaine; Blood Pressure; Catecholamines; Female; Homocysteine; Humans; Hypertension; Indicators and Reagents; Male; Methylation; Niacinamide; Vitamins

2012
Toxic effects of nicotinamide methylation on mouse brain striatum neuronal cells and its relation to manganese.
    Environmental health and preventive medicine, 2012, Volume: 17, Issue:5

    Topics: Animals; Cell Survival; Dithiothreitol; Manganese; Methylation; Mice; Neostriatum; Niacinamide; Nicotinamide N-Methyltransferase

2012
Nicotinamide treatment reduces the levels of histone H3K4 trimethylation in the promoter of the mper1 circadian clock gene and blocks the ability of dexamethasone to induce the acute response.
    Biochimica et biophysica acta, 2012, Volume: 1819, Issue:8

    Topics: Animals; Circadian Clocks; Circadian Rhythm; Dexamethasone; Gene Expression Regulation; Histones; Methylation; Mice; Niacinamide; Oxidoreductases, N-Demethylating; Period Circadian Proteins; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Promoter Regions, Genetic; Sirtuin 1

2012
NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink.
    Nature chemical biology, 2013, Volume: 9, Issue:5

    Topics: Epigenesis, Genetic; Humans; Methionine; Methylation; Models, Genetic; Neoplasms; Niacinamide; Nicotinamide N-Methyltransferase

2013
Heterochromatinization induced by GAA-repeat hyperexpansion in Friedreich's ataxia can be reduced upon HDAC inhibition by vitamin B3.
    Human molecular genetics, 2013, Jul-01, Volume: 22, Issue:13

    Topics: Acetylation; Animals; Cell Line, Transformed; Chromatin; Deoxyribonuclease I; Epistasis, Genetic; Frataxin; Friedreich Ataxia; Gene Expression Regulation; Gene Order; Genetic Loci; Heterochromatin; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Iron-Binding Proteins; Methylation; Mice; Mice, Transgenic; Models, Biological; Niacinamide; Trinucleotide Repeat Expansion

2013
Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide.
    Nature chemical biology, 2013, Volume: 9, Issue:11

    Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Longevity; Methylation; Niacinamide; Sirtuins

2013
Human mass balance, metabolite profile and identification of metabolic enzymes of [¹⁴C]ASP015K, a novel oral janus kinase inhibitor.
    Xenobiotica; the fate of foreign compounds in biological systems, 2015, Volume: 45, Issue:10

    Topics: Adamantane; Administration, Oral; Adolescent; Adult; Carbon Radioisotopes; Feces; Humans; Janus Kinases; Male; Metabolic Clearance Rate; Methylation; Middle Aged; Niacinamide; Nicotinamide N-Methyltransferase; Protein Kinase Inhibitors; Sulfotransferases; Young Adult

2015
The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition.
    Nature cell biology, 2015, Volume: 17, Issue:12

    Topics: Animals; Blotting, Western; Cell Differentiation; Cells, Cultured; Embryonic Stem Cells; Epigenesis, Genetic; Gas Chromatography-Mass Spectrometry; Gene Expression Profiling; Gene Knockdown Techniques; Histones; Human Embryonic Stem Cells; Humans; Lysine; Mass Spectrometry; Metabolome; Metabolomics; Methylation; Mice; Niacinamide; Nicotinamide N-Methyltransferase; Proteomics; Reverse Transcriptase Polymerase Chain Reaction; S-Adenosylmethionine; Signal Transduction

2015
Comparison of the effects of nicotinic acid and nicotinamide degradation on plasma betaine and choline levels.
    Clinical nutrition (Edinburgh, Scotland), 2017, Volume: 36, Issue:4

    Topics: Adult; Betaine; Blood Pressure; Choline; Dietary Supplements; Food, Fortified; Homocysteine; Humans; Hydrolysis; Kinetics; Male; Metanephrine; Methylation; Niacin; Niacinamide; Normetanephrine; Pyridones; Random Allocation; Young Adult

2017
Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells.
    Cell chemical biology, 2017, Mar-16, Volume: 24, Issue:3

    Topics: Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Crystallography, X-Ray; Glycine; HeLa Cells; Histones; Humans; Kaplan-Meier Estimate; Ketoglutaric Acids; Methylation; Multiple Myeloma; Niacinamide; Protein Isoforms; Pyridines; Retinoblastoma-Binding Protein 2; Transcription Initiation Site

2017
Dysfunction of IKZF1/MYC/MDIG axis contributes to liver cancer progression through regulating H3K9me3/p21 activity.
    Cell death & disease, 2017, 05-04, Volume: 8, Issue:5

    Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Dioxygenases; Disease Progression; Histone Demethylases; Histones; Humans; Ikaros Transcription Factor; Liver Neoplasms; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Niacinamide; Nuclear Proteins; Phenylurea Compounds; Promoter Regions, Genetic; Proto-Oncogene Proteins c-myc; Signal Transduction; Sorafenib; Transplantation, Heterologous

2017
Citrullination Inactivates Nicotinamide- N-methyltransferase.
    ACS chemical biology, 2018, 09-21, Volume: 13, Issue:9

    Topics: Citrullination; Enzyme Activation; Humans; Kinetics; Methylation; Models, Molecular; Mutagenesis, Site-Directed; Niacinamide; Nicotinamide N-Methyltransferase; Protein Conformation

2018
Kinetic Mechanism of Nicotinamide N-Methyltransferase.
    Biochemistry, 2018, 09-25, Volume: 57, Issue:38

    Topics: Humans; Kinetics; Methylation; NAD; Niacinamide; Nicotinamide N-Methyltransferase; S-Adenosylmethionine

2018
Canonical Wnt is inhibited by targeting one-carbon metabolism through methotrexate or methionine deprivation.
    Proceedings of the National Academy of Sciences of the United States of America, 2019, 02-19, Volume: 116, Issue:8

    Topics: Carbon; Endosomes; Glycogen Synthase Kinase 3 beta; HEK293 Cells; HeLa Cells; Humans; Lysosomes; Methionine; Methotrexate; Methylation; Niacinamide; Protein-Arginine N-Methyltransferases; Repressor Proteins; S-Adenosylmethionine; Wnt Signaling Pathway

2019
Rational Adaptation of L3MBTL1 Inhibitors to Create Small-Molecule Cbx7 Antagonists.
    ChemMedChem, 2019, 08-06, Volume: 14, Issue:15

    Topics: Amino Acid Sequence; Enzyme Inhibitors; Humans; Lysine; Methylation; Models, Molecular; Molecular Structure; Niacinamide; Polycomb Repressive Complex 1; Protein Binding; Protein Conformation; Repressor Proteins; Structure-Activity Relationship; Sulfonamides; Tumor Suppressor Proteins

2019
Melatonin Alleviates the Toxicity of High Nicotinamide Concentrations in Oocytes: Potential Interaction with Nicotinamide Methylation Signaling.
    Oxidative medicine and cellular longevity, 2021, Volume: 2021

    Topics: Apoptosis; Female; Humans; Melatonin; Methylation; Niacinamide; Oocytes; Signal Transduction

2021
    Vestnik oftalmologii, 2022, Volume: 138, Issue:5

    Topics: Binding Sites; Dose Fractionation, Radiation; Humans; Meningeal Neoplasms; Meningioma; Methylation; Niacinamide; Nicotinamide N-Methyltransferase; Optic Nerve; Optic Nerve Neoplasms; Prospective Studies; Treatment Outcome; Visual Acuity

2022