niacinamide and hexobarbital

niacinamide has been researched along with hexobarbital in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199020 (95.24)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (4.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Klinger, W; Muller, D1
Ahmad, N; Bederka, JP; Davitiyananda, D; Moses, ML1
Greene, FE; Hilliard, CC; Holl, JE; Molton, E; Wade, AE1
Coper, H; Deyhle, G; Veit, J; von Herrath, D1
Brenner, G; Trautmann, H1
Schenkman, JB1
Lison, H1
Bickel, MH; Gigon, PL1
Wilson, JT1
Absil, J; Buchel, L1
Brownie, AC; Elmamlouk, TH; Gessner, T1
Greengard, P; Quinn, GP; Reid, MB1
Franklin, MR1
Fouts, JR; Gram, TE1
Gigon, PL; Gillette, JR; Gram, TE2
Coper, H; Veit, J; von Herrath, D1
Gillette, JR; Sasame, HA1
Igarashi, T; Kitagawa, H; Satoh, T; Sugiyama, S; Ueno, K; Uzalp, B1
Badawy, AA; Morgan, CJ1

Reviews

1 review(s) available for niacinamide and hexobarbital

ArticleYear
Developmental pharmacology: a review of its application to clinical and basic science.
    Annual review of pharmacology, 1972, Volume: 12

    Topics: Aging; Androgens; Aniline Compounds; Animals; Estrogens; Ethanol; Female; Fetus; Fluorosis, Dental; Gestational Age; Glutethimide; Hexobarbital; Humans; Hyperbilirubinemia; Hyperbilirubinemia, Hereditary; Infant, Newborn; Infant, Newborn, Diseases; Liver; Male; Niacinamide; Oxidoreductases; Pharmacology; Phenobarbital; Pregnancy; Rabbits; Rats; Tetracycline

1972

Other Studies

20 other study(ies) available for niacinamide and hexobarbital

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developmental aspects of xenobiotic transformation.
    Environmental health perspectives, 1976, Volume: 18

    Topics: Aminopyrine; Aniline Compounds; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Ethylmorphine; Female; Glucosephosphates; Hexobarbital; Hydrogen-Ion Concentration; Metyrapone; Microsomes, Liver; NAD; NADP; Niacinamide; Oxidoreductases, N-Demethylating; Oxidoreductases, O-Demethylating; Phenobarbital; Pregnancy; Rats; Semicarbazides

1976
Drug-biomolecule interactions: drug toxicity and vitamin coenzyme depletion.
    Journal of pharmaceutical sciences, 1975, Volume: 64, Issue:3

    Topics: Animals; Coenzymes; Female; Hexobarbital; Lethal Dose 50; Mice; Motor Activity; NADP; Niacinamide; Nicotinic Acids; Nucleotides; Rats; Sleep; Time Factors

1975
Alteration of drug metabolism in rats and mice by an environment of cedarwood.
    Pharmacology, 1968, Volume: 1, Issue:5

    Topics: Aniline Compounds; Animals; Azo Compounds; Dextroamphetamine; Dicumarol; Environment; Glucose; Hexobarbital; Indenes; Liver; Magnesium Sulfate; Male; Mice; Microsomes; NADP; Naphthalenes; Niacinamide; Rats; Sleep; Sulfanilamides; Sulfonamides; Terpenes; Wood; Zoxazolamine

1968
[About mechanisms of sleep-extending effect of various drugs].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 260, Issue:4

    Topics: Animals; Central Nervous System; Female; Hexobarbital; Isoniazid; Isonicotinic Acids; Liver; Microsomes; Niacinamide; Pentosephosphates; Psychopharmacology; Pyridines; Rats; Sleep; Time Factors

1968
[Effect of xanthinol-nicotinate on detoxification processes in liver. Experimental studies on the model of hexobarbital-narcosis in rat].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:12

    Topics: Anesthesia, General; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Depression, Chemical; Female; Hexobarbital; Liver; Male; Niacinamide; Nicotinic Acids; Pyridines; Rats; Sex Factors; Sleep; Theophylline; Time Factors

1969
Studies on the nature of the type I and type II spectral changes in liver microsomes.
    Biochemistry, 1970, May-12, Volume: 9, Issue:10

    Topics: Aniline Compounds; Animals; Benzopyrenes; Binding Sites; Cytochromes; Heme; Hexobarbital; Male; Microsomes, Liver; Niacinamide; Phenobarbital; Proteins; Rats; Spectrophotometry; Ultraviolet Rays

1970
[Differentiation of functional disturbances of the central nervous system evoked by 6-aminonicotinamide, an antimetabolite of nicotinamide].
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1970, Volume: 267, Issue:2

    Topics: Animals; Antimetabolites; Blood Glucose; Body Temperature; Body Weight; Extrapyramidal Tracts; Female; Hexobarbital; Hyperglycemia; Movement Disorders; Muscle Spasticity; Niacinamide; Rats

1970
Drug metabolism by hepatic microsomes from phenobarbital-treated or starved male and female rats in the presence of inhibitors.
    Life sciences. Pt. 2: Biochemistry, general and molecular biology, 1971, Feb-08, Volume: 10, Issue:3

    Topics: Aminopyrine; Aniline Compounds; Animals; Cytochromes; Female; Hexobarbital; Liver; Male; Methylation; Microsomes, Liver; Morphinans; Niacinamide; Organ Size; Phenobarbital; Proadifen; Rats; Starvation

1971
[Demonstration of a depressive component in the central effects of nikethamide].
    Archives des sciences physiologiques, 1972, Volume: 26, Issue:2

    Topics: Animals; Body Temperature; Central Nervous System; Chloral Hydrate; Drug Synergism; Female; Hexobarbital; Hypnotics and Sedatives; Male; Mice; Niacinamide; Nikethamide; Pentobarbital; Proadifen; Sleep; Time Factors; Wakefulness

1972
Occurrence of cytochrome P-450 in hepatopancreas of Homarus americanus.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1974, Jul-15, Volume: 48, Issue:3

    Topics: Aniline Compounds; Animals; Binding Sites; Carbon Monoxide; Cytochrome P-450 Enzyme System; Digestive System; Female; Hexobarbital; Microsomes; Morphinans; Nephropidae; Niacinamide; Protein Binding; Species Specificity; Spectrophotometry; Spectrophotometry, Ultraviolet; Thiocyanates

1974
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism.
    Molecular pharmacology, 1966, Volume: 2, Issue:4

    Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine

1966
The incomplete conversion of hepatic cytochrome P-450 to P-420 by mercurials.
    Molecular pharmacology, 1972, Volume: 8, Issue:6

    Topics: Aniline Compounds; Animals; Cytochrome P-450 Enzyme System; Cytochromes; Electron Spin Resonance Spectroscopy; Hexobarbital; Hydrogen-Ion Concentration; Hydrolysis; Liver; Mercury; Microsomes, Liver; Morphinans; Niacinamide; Organomercury Compounds; Organometallic Compounds; Phenobarbital; Proteins; Rats; Spectrophotometry; Spectrum Analysis; Trypsin

1972
Further studies on the metabolism of drugs by subfractions of hepatic microsomes. 3. Effects of the NADPH-generating system.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 158, Issue:2

    Topics: Aminopyrine; Aniline Compounds; Animals; Buffers; Citrates; Enzyme Induction; Glucosephosphate Dehydrogenase; Hexobarbital; Hexosephosphates; Isocitrate Dehydrogenase; Liver; Male; Microsomes; Mixed Function Oxygenases; NADP; Niacinamide; Rabbits

1967
Effect of drug substrates on the reduction of hepatic microsomal cytochrome P-450 by NADPH.
    Biochemical and biophysical research communications, 1968, May-23, Volume: 31, Issue:4

    Topics: Aminopyrine; Aniline Compounds; Animals; Cytochromes; Ethylamines; Female; Hexobarbital; Imipramine; Kinetics; Liver; Male; Microsomes; Morphine; NADP; Niacinamide; Oxidation-Reduction; Pigments, Biological; Proadifen; Rats; Sex Factors; Spectrophotometry; Transferases

1968
On the mechanism of the sleep-prolonging effect of antimetabolites of nicotinamide.
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 259, Issue:2

    Topics: Anesthesia; Animals; Antimetabolites; Brain; Central Nervous System; Glucosephosphate Dehydrogenase; Hexobarbital; Malate Dehydrogenase; NADP; Niacinamide; Paralysis; Pentosephosphates; Pyridines; Rats; Sleep

1968
Studies on the rate of reduction of hepatic microsomal cytochrome P-450 by reduced nicotinamide adenine dinucleotide phosphate: effect of drug substrates.
    Molecular pharmacology, 1969, Volume: 5, Issue:2

    Topics: Aminopyrine; Aniline Compounds; Animals; Carbon Monoxide; Cytochromes; Ethylamines; Female; Hexobarbital; Imipramine; In Vitro Techniques; Kinetics; Liver; Male; Methylcholanthrene; Microsomes; Morphinans; NADP; Niacinamide; Oxidation-Reduction; Proadifen; Rats; Sex Factors; Spectrophotometry; Time Factors; Valerates

1969
Studies on the relationship between the effects of various substances on absorption spectrum of cytochrome P-450 and the reduction of p-nitrobenzoate by mouse liver microsomes.
    Molecular pharmacology, 1969, Volume: 5, Issue:2

    Topics: Aminopyrine; Aniline Compounds; Animals; Benzoates; Carbon Monoxide; Cytochromes; Ethylamines; Hexobarbital; Imidazoles; In Vitro Techniques; Kinetics; Liver; Male; Mice; Microsomes; Morphinans; NADP; Niacinamide; Oxidation-Reduction; Oxidoreductases; Proadifen; Pyridines; Spectrophotometry

1969
Effects of a single administration of 6-aminonicotinamide on hepatic microsomal drug metabolism in rats.
    Archives internationales de pharmacodynamie et de therapie, 1984, Volume: 269, Issue:1

    Topics: 6-Aminonicotinamide; Animals; Brain; Hexobarbital; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Mixed Function Oxygenases; Niacinamide; Pharmaceutical Preparations; Potassium Chloride; Rats; Rats, Inbred Strains; Sleep

1984
Tryptophan pyrrolase in haem regulation. The relationship between the depletion of rat liver tryptophan pyrrolase haem and the enhancement of 5-aminolaevulinate synthase activity by 2-allyl-2-isopropylacetamide.
    The Biochemical journal, 1980, Mar-15, Volume: 186, Issue:3

    Topics: 5-Aminolevulinate Synthetase; Acetamides; Allylisopropylacetamide; Animals; Heme; Hexobarbital; Kinetics; Liver; Male; Methylphenazonium Methosulfate; Niacinamide; Rats; Tryptophan Oxygenase

1980