niacinamide has been researched along with glyburide in 90 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.11) | 18.7374 |
| 1990's | 76 (84.44) | 18.2507 |
| 2000's | 3 (3.33) | 29.6817 |
| 2010's | 8 (8.89) | 24.3611 |
| 2020's | 2 (2.22) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Auchampach, JA; Cavero, I; Gross, GJ | 1 |
| Kreye, VA; Lenz, T; Pfründer, D; Theiss, U | 1 |
| Lathrop, DA; Refsum, H; Tande, PM; Yang, T | 1 |
| Gross, GJ; Pieper, GM | 1 |
| Braida, C; Holzmann, S; Kukovetz, WR; Pöch, G | 1 |
| Cook, D; Stockbridge, N; Vollrath, B; Weir, B; Zhang, H | 1 |
| Akima, M; Imagawa, J; Nabata, H; Taira, N | 1 |
| Fukata, Y; Fukushima, H; Jinno, Y; Kaneta, S; Nishikori, K; Ogawa, N | 1 |
| Kau, ST; Li, JH; Zografos, P | 1 |
| Kamijo, T; Kido, H; Miwa, A; Nakamura, F; Sugimoto, T; Tomaru, T; Uchida, Y | 1 |
| Hamaguchi, M; Imai, S; Ishibashi, T | 1 |
| Borg, C; Cavero, I; Mestre, M; Mondot, S | 1 |
| Higuera, TR; Kadowitz, PJ; Kvamme, P; Minkes, RK; Nossaman, BD | 1 |
| Kreye, VA; Lenz, T; Theiss, U | 1 |
| Satoh, K; Taira, N; Yamada, H | 1 |
| Ksoll, E; Mackert, JR; Parsons, AA; Schilling, L; Wahl, M | 1 |
| Arakawa, C; Kasuya, Y; Masuda, Y; Miyajima, M; Shigenobu, K; Tanaka, S; Yamashita, T | 1 |
| Fan, Z; Hiraoka, M; Marumo, F; Nakayama, K; Sawanobori, T | 1 |
| Fukamachi, K; Fukumura, F; Kinoshita, K; Kurisu, K; Mitani, A; Nakashima, A; Sakamoto, M; Tokunaga, K; Tsuruhara, Y | 1 |
| Fukushima, H; Harada, K; Jinno, Y; Nishikori, K; Ogawa, N; Ohta, H | 1 |
| Satoh, K; Taira, N; Yamada, H; Yoneyama, F | 1 |
| Taira, N; Teshigawara, T; Yanagisawa, T | 1 |
| Satoh, E; Taira, N; Yanagisawa, T | 1 |
| Satoh, K; Taira, N; Yoneyama, F | 1 |
| Eltze, M | 1 |
| Satoh, H | 2 |
| Kinoshita, M; Nakae, I; Quan, L; Sugimoto, Y; Tsutamoto, T | 1 |
| Fukushima, H; Harada, K; Izawa, T; Kaneta, S; Miwa, A; Ogawa, N | 1 |
| Fukushima, H; Jinno, Y; Kaneta, S; Miwa, A; Ogawa, N | 1 |
| Dawodu, AA; Iwashiro, K; Monti, F; Puddu, PE; Schiariti, M; Sugimoto, S | 1 |
| Masuda, Y; Tanaka, S; Yamashita, T | 1 |
| Bender, AS; White, HS; Woodbury, DM | 1 |
| Orito, K; Satoh, K; Taira, N; Yoneyama, F | 1 |
| Auchampach, JA; Gross, GJ; Pieper, GM; Yao, Z | 1 |
| Akamatsu, S; Dohi, S; Iida, H; Ishiyama, T; Ohta, S; Shimonaka, H | 1 |
| Inukai, H; Murase, K; Park, JB; Ryu, PD; Tanifuji, M; Yamashita, S | 1 |
| Campa, PP; Marino, B; Monti, F; Puddu, PE; Schiariti, M; Sugimoto, S | 1 |
| Hashimoto, K; Kinoshita, M; Nakae, I; Quan, L; Sugimoto, Y; Tsutamoto, T | 1 |
| Fukata, Y; Fukushima, H; Harada, K; Kasai, H; Ogawa, N | 1 |
| Fukata, Y; Fukushima, H; Jinno, Y; Kaneta, S; Ogawa, N; Okada, Y; Yokoyama, T | 1 |
| Abe, S; Kanaide, H; Nakamura, M; Nishimura, J | 1 |
| Jun, JY; Kim, KW; Kim, SJ | 1 |
| Iimura, O; Itoya, M; Iwamoto, T; Miura, T; Shimamoto, K; Urabe, K | 1 |
| Mori, T; Satoh, K; Taira, N; Yamada, H | 1 |
| Fukata, Y; Fukushima, H; Jinno, Y; Kaneta, S; Miwa, A; Ogawa, N | 1 |
| Nakaya, H | 1 |
| Fukushima, H; Jinno, Y; Kaneta, S; Kasai, H; Miwa, A; Motoki, K; Ogawa, N; Okada, Y | 1 |
| Allard, B; Lazdunski, M | 1 |
| Okamoto, K; Sakuta, H; Watanabe, Y | 1 |
| Okamoto, K; Sakuta, H | 1 |
| Auchampach, JA; Gross, GJ; Warltier, DC | 1 |
| Campa, PP; Dawodu, AA; del Monte, F; Marino, B; Monti, F; Puddu, PE; Schiariti, M; Sugimoto, S | 1 |
| Bloch, G; Grousset, C; Kevelaitis, E; Menasché, P; Mouas, C; Piwnica, A | 1 |
| Akai, K; Kanatsuka, H; Komaru, T; Kumagai, T; Sato, K; Sekiguchi, N; Shirato, K; Sugimura, A; Wang, Y | 1 |
| Hara, Y; Kimura, S; Kobayashi, S; Masuda, Y; Nakaya, H; Saito, T; Takizawa, T | 1 |
| O'Rourke, ST | 1 |
| Gross, GJ; Mizumura, T; Nithipatikom, K | 1 |
| Jahangir, A; Jahangir, R; López, JR; Shen, WK; Terzic, A | 1 |
| Asayama, J; Katamura, M; Kawahara, A; Kobara, M; Matoba, S; Nakagawa, C; Nakagawa, M; Ohta, B; Tanaka, T; Tatsumi, T; Tsuruyama, K | 1 |
| Chujo, M; Hori, M; Inoue, M; Kamada, T; Kitakaze, M; Komamura, K; Minamino, T; Mori, H; Node, K; Shinozaki, Y | 1 |
| Angus, JA; Fujiwara, T | 1 |
| Brading, AF; Teramoto, N | 1 |
| Horio, Y; Isomoto, S; Kondo, C; Kurachi, Y; Matsumoto, S; Shindo, T; Yamada, M | 1 |
| Cavero, I; Gross, GJ; Schultz, JE; Yao, Z | 1 |
| Kinoshita, M; Liu, Q; Matsumoto, T; Nakae, I; Omura, T; Takahashi, M; Takaoka, A | 1 |
| Houchi, H; Nakaya, Y; Oka, M; Shono, M | 1 |
| André-Fouät, X; Loufoua, J; Minaire, Y; Ovize, M; Pop, C; Rioufol, G | 1 |
| Arai, M; Fujiwara, H; Fujiwara, T; Kariya, T; Minatoguchi, S; Ohno, Y; Uno, Y; Yamashita, K | 1 |
| Saito, K; Sakai, K | 4 |
| Cogolludo, AL; Pérez-Vizcaíno, F; Tamargo, J; Villamor, E | 1 |
| Asanagi, M; Miyazaki, T; Miyoshi, S; Moritani, K; Ogawa, S | 1 |
| Davie, CS; Standen, NB | 1 |
| Akima, M; Kamachi, S; Kitajima, S; Moriyasu, M; Sakai, K | 1 |
| Heywood, GJ; Thomas, PS | 1 |
| Di Girolamo, N; Heywood, GJ; Thomas, PS; Wei, XM | 1 |
| Hayakawa, M; Matsuyama-Yokono, A; Nakano, R; Shibasaki, M; Shiraki, K; Someya, Y; Tahara, A | 1 |
| Badole, SL; Bodhankar, SL | 1 |
| Husain, GM; Kumar, V; Singh, PN; Singh, RK | 1 |
| Beil, W; Holstein, A; Kovacs, P | 1 |
| Chellappan, DR; Krishnasamy, G; Muthusamy, K; Subbiah, N | 1 |
| Abdellatief, SA; Beheiry, RR; El-Mandrawy, SAM | 1 |
| Indumathi, D; Srinivasan, S; Sujithra, K; Vinothkumar, V | 1 |
| Boone, K; Ezike, T; Omizu, B; Omoaghe, A; Oyesola, O | 1 |
| Abdollahi, M; Farahani, H; Heidari, H; Khalaj, A; Khani, S | 1 |
1 review(s) available for niacinamide and glyburide
| Article | Year |
|---|---|
[Potential role of ATP-sensitive K+ channels in ischemia- and reperfusion-induced arrhythmias].
Topics: Action Potentials; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Benzopyrans; Cromakalim; Glyburide; Guanidines; Humans; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Niacinamide; Nicorandil; Pinacidil; Potassium; Potassium Channels; Pyrroles; Tolbutamide | 1993 |
89 other study(ies) available for niacinamide and glyburide
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Nicorandil attenuates myocardial dysfunction associated with transient ischemia by opening ATP-dependent potassium channels.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Blood Pressure; Coronary Circulation; Dogs; Female; Glyburide; Heart; Heart Rate; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Niacinamide; Nicorandil; Potassium Channels; Ventricular Function, Left | 1992 |
Pharmacological characterization of nicorandil by 86Rb efflux and isometric vasorelaxation studies in vascular smooth muscle.
Topics: Animals; Aorta; Benzopyrans; Cromakalim; Glyburide; In Vitro Techniques; Niacinamide; Nicorandil; Nitroprusside; Potassium Channels; Pyrroles; Rabbits; Rubidium Radioisotopes; Vasodilation; Vasodilator Agents | 1992 |
Class III antiarrhythmic action by potassium channel blockade: dofetilide attenuates hypoxia induced electromechanical changes.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Glyburide; Guinea Pigs; Muscles; Niacinamide; Nicorandil; Oxygen; Papillary Muscles; Phenethylamines; Potassium Channels; Sulfonamides; Vasodilator Agents | 1992 |
Anti-free-radical and neutrophil-modulating properties of the nitrovasodilator, nicorandil.
Topics: Animals; Dogs; Dose-Response Relationship, Drug; Free Radical Scavengers; Free Radicals; Glyburide; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Neutrophils; Niacinamide; Nicorandil; Nitroglycerin; Opsonin Proteins; Superoxides; Tetradecanoylphorbol Acetate; Vasodilator Agents | 1992 |
Pharmacological interaction experiments differentiate between glibenclamide-sensitive K+ channels and cyclic GMP as components of vasodilation by nicorandil.
Topics: Animals; Benzopyrans; Cattle; Coronary Vessels; Cromakalim; Cyclic GMP; Drug Interactions; Glyburide; Guanidines; In Vitro Techniques; Methylene Blue; Molsidomine; Muscle Relaxation; Niacinamide; Nicorandil; Nitroprusside; Pinacidil; Potassium Channels; Pyrroles; Sensitivity and Specificity; Vasodilator Agents | 1992 |
Vasodilatation of canine cerebral arteries by nicorandil, pinacidil and lemakalim.
Topics: Animals; Basilar Artery; Benzopyrans; Cerebral Arteries; Cromakalim; Dogs; Female; Glyburide; Guanidines; Guanylate Cyclase; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Pyrroles; Vasodilation; Vasodilator Agents | 1992 |
Spasmolytic action of nicorandil in canine conductive coronary arteries in vivo is not modified by glibenclamide.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiocardiography; Animals; Benzopyrans; Coronary Circulation; Coronary Vasospasm; Coronary Vessels; Cromakalim; Dogs; Female; Glyburide; Male; Niacinamide; Nicorandil; Nitroglycerin; Parasympatholytics; Potassium Channels; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Vasodilator Agents | 1992 |
Comparison of KRN2391 with nicorandil and nifedipine on canine coronary blood flow: antagonism by glibenclamide.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Female; Glyburide; Heart Rate; Male; Niacinamide; Nicorandil; Nifedipine; Potassium Channels; Pyridines; Vascular Resistance | 1992 |
Comparison of the in vitro effects of K+ channel modulators on detrusor and portal vein strips from guinea pigs.
Topics: Animals; Benzopyrans; Cromakalim; Dose-Response Relationship, Drug; Glyburide; Guanidines; Guinea Pigs; In Vitro Techniques; Male; Minoxidil; Muscle, Smooth; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Pinacidil; Portal Vein; Potassium Channels; Potassium Chloride; Pyrroles; Vasoconstriction; Vasodilator Agents | 1992 |
[The vasospasmolytic effects of nicorandil, cromakalim and pinacidil on 3,4-diaminopyridine-induced phasic contractions in canine coronary arteries as an experimental vasospasm model].
Topics: 4-Aminopyridine; Amifampridine; Animals; Benzopyrans; Coronary Vasospasm; Cromakalim; Disease Models, Animal; Dogs; Female; Glyburide; Guanidines; In Vitro Techniques; Ion Channel Gating; Male; Methylene Blue; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Pyrroles; Vasodilator Agents | 1992 |
2-Nicotinamidoethyl acetate (SG-209) is a potassium channel opener: structure activity relationship among nicorandil derivatives.
Topics: Animals; Cyclic GMP; Glyburide; Male; Methylene Blue; Niacinamide; Nicorandil; Phenylephrine; Potassium Channels; Rabbits; Structure-Activity Relationship; Vasodilation; Vasodilator Agents | 1991 |
Nicorandil: differential contribution of K+ channel opening and guanylate cyclase stimulation to its vasorelaxant effects on various endothelin-1-contracted arterial preparations. Comparison to aprikalim (RP 52891) and nitroglycerin.
Topics: Animals; Coronary Vessels; Endothelins; Endothelium, Vascular; Glyburide; Guanylate Cyclase; Heart; Hemodynamics; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Picolines; Potassium Channels; Purinones; Pyrans; Rats; Rats, Inbred Strains; Stimulation, Chemical; Swine; Swine, Miniature; Vasodilator Agents | 1991 |
Analysis of pulmonary and systemic vascular responses to cromakalim, an activator of K+ATP channels.
Topics: Adenosine Triphosphate; Animals; Antihypertensive Agents; Benzopyrans; Blood Circulation; Cats; Cromakalim; Endothelins; Glyburide; Guanidines; Heart Rate; Hindlimb; Myocardial Contraction; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Pulmonary Circulation; Pyrroles; Vascular Resistance; Vasodilator Agents; Ventricular Function, Right | 1991 |
The dualistic mode of action of the vasodilator drug, nicorandil, differentiated by glibenclamide in 86Rb flux studies in rabbit isolated vascular smooth muscle.
Topics: Animals; Aorta; Benzopyrans; Cromakalim; Glyburide; Membranes; Muscle Contraction; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Norepinephrine; Potassium; Potassium Channels; Pyrroles; Rabbits; Rubidium Radioisotopes; Stimulation, Chemical; Vasodilator Agents | 1991 |
Differential antagonism by glibenclamide of the relaxant effects of cromakalim, pinacidil and nicorandil on canine large coronary arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arteries; Benzopyrans; Coronary Vessels; Cromakalim; Dogs; Dose-Response Relationship, Drug; Female; Glyburide; Guanidines; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Pinacidil; Potassium; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Vasodilator Agents | 1991 |
Analysis of cromakalim-, pinacidil-, and nicorandil-induced relaxation of the 5-hydroxytryptamine precontracted rat isolated basilar artery.
Topics: Animals; Basilar Artery; Benzopyrans; Cromakalim; Drug Interactions; Glyburide; Guanidines; Male; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Pyrroles; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Vasoconstriction; Vasodilation; Vasodilator Agents | 1991 |
Potassium channel opening properties of a novel compound, NIP-121, cromakalim and nicorandil in rat aorta and portal vein.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Benzopyrans; Cromakalim; Glyburide; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Oxadiazoles; Phentolamine; Piperidines; Portal Vein; Potassium Channels; Potassium Chloride; Pyrroles; Rats; Rats, Inbred Strains; Rubidium Radioisotopes | 1991 |
Action of nicorandil on ATP-sensitive K+ channel in guinea-pig ventricular myocytes.
Topics: Adenosine Triphosphate; Animals; Glyburide; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Kinetics; Myocardium; Niacinamide; Nicorandil; Potassium Channels; Vasodilator Agents | 1991 |
Effects of glibenclamide and nicorandil on cardiac function during ischemia and reperfusion in isolated perfused rat hearts.
Topics: Adenosine Triphosphate; Animals; Coronary Disease; Glyburide; Heart; Kinetics; Male; Myocardial Contraction; Myocardial Reperfusion; Niacinamide; Nicorandil; Potassium; Potassium Channels; Rats; Rats, Inbred Strains; Ventricular Function, Left | 1991 |
Cardioprotective effects of KRN2391 and nicorandil on ischemic dysfunction in perfused rat heart.
Topics: Animals; Coronary Disease; Cytosol; Glyburide; Heart Rate; In Vitro Techniques; Male; Myocardium; Niacinamide; Nicorandil; Perfusion; Pyridines; Rats; Rats, Inbred Strains; Vasodilator Agents | 1991 |
Specific but differential antagonism by glibenclamide of the vasodepressor effects of cromakalim and nicorandil in spinally-anaesthetized dogs.
Topics: Anesthesia, Spinal; Animals; Benzopyrans; Blood Pressure; Calcium Channel Blockers; Cromakalim; Diltiazem; Dogs; Dose-Response Relationship, Drug; Female; Glyburide; Heart Rate; Hemodynamics; Male; Myocardial Contraction; Niacinamide; Nicorandil; Nitroglycerin; Norepinephrine; Potassium Channels; Pyrroles | 1990 |
Cytoplasmic calcium and the relaxation of canine coronary arterial smooth muscle produced by cromakalim, pinacidil and nicorandil.
Topics: Adenosine Triphosphate; Animals; Benzopyrans; Calcium; Coronary Vessels; Cromakalim; Cytoplasm; Dogs; Female; Fluorescence; Glyburide; Guanidines; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Pinacidil; Potassium Chloride; Pyrroles; Quaternary Ammonium Compounds | 1990 |
Specific antagonism by glibenclamide of negative inotropic effects of potassium channel openers in canine atrial muscle.
Topics: Animals; Benzopyrans; Carbachol; Cromakalim; Dogs; Female; Glyburide; Guanidines; Heart Atria; Male; Myocardial Contraction; Niacinamide; Nicorandil; Nifedipine; Pinacidil; Potassium Channels; Pyrroles; Vasodilator Agents | 1990 |
Nicorandil increases coronary blood flow predominantly by K-channel opening mechanism.
Topics: Adenosine Triphosphate; Animals; Benzopyrans; Coronary Circulation; Cromakalim; Dogs; Dose-Response Relationship, Drug; Female; Glyburide; In Vitro Techniques; Male; Myocardial Contraction; Niacinamide; Nicorandil; Nitroglycerin; Potassium Channels; Pyrroles; Vasodilator Agents | 1990 |
Glibenclamide is a competitive antagonist of cromakalim, pinacidil and RP 49356 in guinea-pig pulmonary artery.
Topics: Animals; Benzopyrans; Cromakalim; Glyburide; Guanidines; Guinea Pigs; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Picolines; Pinacidil; Potassium Channels; Potassium Chloride; Pulmonary Artery; Purinones; Pyrans; Pyrroles; Tetraethylammonium Compounds | 1989 |
Effects of ATP-sensitive K+ channel openers on pacemaker activity in isolated single rabbit sino-atrial node cells.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Electrophysiology; Glyburide; Guanidines; Heart Rate; In Vitro Techniques; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Pyrroles; Rabbits; Sinoatrial Node; Vasodilator Agents | 1993 |
Glibenclamide-induced oscillation of canine coronary artery is independent of myocardial ischemia.
Topics: Adenosine Triphosphate; Animals; Arginine; Benzopyrans; Coronary Circulation; Coronary Vessels; Cromakalim; Diltiazem; Dogs; Female; Glyburide; In Vitro Techniques; Male; Muscle Tonus; Muscle, Smooth, Vascular; Myocardial Ischemia; Niacinamide; Nicorandil; Nitroarginine; Nitroglycerin; Potassium Channels; Pyrroles; Vasodilator Agents | 1994 |
Effects of KRN2391, nicorandil and diltiazem on the changes in the electrocardiogram caused by endothelin-1 in anaesthetized rats.
Topics: Action Potentials; Anesthesia; Animals; Blood Pressure; Cardiac Complexes, Premature; Diltiazem; Electrocardiography; Electrophysiology; Endothelins; Glyburide; Guinea Pigs; Heart Rate; In Vitro Techniques; Male; Methacholine Compounds; Niacinamide; Nicorandil; Pyridines; Rats; Rats, Wistar; Vasodilator Agents; Ventricular Fibrillation | 1993 |
Effect of KRN2391 on venous return: comparison with other vasodilators.
Topics: Animals; Benzopyrans; Cromakalim; Dogs; Female; Glyburide; Hemodynamics; Male; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Potassium Channels; Pyridines; Pyrroles; Vasodilator Agents; Veins | 1993 |
The risk of myocardial stunning is decreased concentration-dependently by KATP channel activation with nicorandil before high K+ cardioplegia.
Topics: Adenosine Triphosphate; Animals; Cardioplegic Solutions; Cardiotonic Agents; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glyburide; Guinea Pigs; Heart Arrest, Induced; Hypothermia, Induced; Isotonic Solutions; Models, Cardiovascular; Multivariate Analysis; Myocardial Contraction; Myocardial Stunning; Niacinamide; Nicorandil; Potassium Channels; Pressure; Risk Factors; Time Factors; Vasodilator Agents | 1995 |
The effects of potassium channel openers and blockers on the specific binding sites for [3H]glibenclamide in rat tissues.
Topics: Animals; Binding Sites; Brain; Cell Membrane; Dose-Response Relationship, Drug; Glyburide; Heart Ventricles; Male; Muscle Contraction; Niacinamide; Nicorandil; Oxadiazoles; Piperidines; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Rubidium; Vasodilator Agents | 1995 |
Ionic dependence of adenosine uptake into cultured astrocytes.
Topics: Adenosine; Animals; Animals, Newborn; Astrocytes; Benzopyrans; Biological Transport; Calcimycin; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cells, Cultured; Cerebral Cortex; Cromakalim; Furosemide; Glyburide; Ionophores; Kinetics; Mice; Niacinamide; Nicorandil; Nigericin; Omeprazole; Potassium; Pyrroles; Sodium; Valinomycin; Vasodilator Agents | 1994 |
A further study of the vasodilator and negative inotropic mechanisms of action of nicorandil and its congeners in the canine heart.
Topics: Animals; Coronary Circulation; Depression, Chemical; Dogs; Drug Interactions; Female; Glyburide; Heart; In Vitro Techniques; Male; Myocardial Contraction; Niacinamide; Nicorandil; Papillary Muscles; Potassium Channels; Vasodilator Agents | 1994 |
The ATP-regulated potassium channel in ischemia-reperfusion injury.
Topics: Adenosine Triphosphate; Animals; Dogs; Glyburide; Ion Channel Gating; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion Injury; Niacinamide; Nicorandil; Picolines; Potassium Channels; Pyrans; Tolbutamide | 1994 |
Mechanisms of vasodilation of cerebral vessels induced by the potassium channel opener nicorandil in canine in vivo experiments.
Topics: Administration, Topical; Animals; Arterioles; Benzopyrans; Cromakalim; Dimethyl Sulfoxide; Dogs; Glyburide; Methylene Blue; Microcirculation; Niacinamide; Nicorandil; Nitroglycerin; Pia Mater; Pyrroles; Vasodilation; Vasodilator Agents; Venules | 1994 |
Possible presence of the ATP-sensitive K+ channel in isolated spinal dorsal horn neurons of the rat.
Topics: Adenosine Triphosphate; Animals; Cell Separation; Electric Stimulation; Electrophysiology; Glyburide; Minoxidil; Neurons; Niacinamide; Nicorandil; Potassium Channels; Rats; Rats, Sprague-Dawley; Spinal Cord | 1994 |
Pretreatment with the adenosine triphosphate-sensitive potassium channel opener nicorandil and improved myocardial protection during high-potassium cardioplegic hypoxia.
Topics: Action Potentials; Animals; Cardioplegic Solutions; Female; Glyburide; Guinea Pigs; Heart Arrest, Induced; Hypothermia, Induced; In Vitro Techniques; Myocardial Contraction; Niacinamide; Nicorandil; Papillary Muscles; Potassium; Potassium Channels; Time Factors; Vasodilator Agents | 1994 |
Mechanism of the vasodilatory action of nicorandil on coronary circulation in dogs.
Topics: Animals; Benzopyrans; Coronary Circulation; Coronary Vessels; Cromakalim; Dogs; Dose-Response Relationship, Drug; Female; Glyburide; Hemodynamics; Injections, Intravenous; Male; Niacinamide; Nicorandil; Nitroglycerin; Potassium Channels; Pyrroles; Vasodilator Agents | 1994 |
Dissimilarity in the mechanisms of action of KRN2391, nicorandil and cromakalim in canine renal artery.
Topics: Animals; Benzopyrans; Cromakalim; Dogs; Female; Glyburide; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitrates; Potassium Channels; Potassium Chloride; Pyridines; Pyrroles; Renal Artery; Vasodilator Agents | 1993 |
Mechanism of action of KRN2391 in canine coronary vascular bed.
Topics: Animals; Antihypertensive Agents; Arteries; Benzopyrans; Coronary Circulation; Coronary Vessels; Cromakalim; Dogs; Drug Interactions; Female; Glyburide; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Pyridines; Pyrroles; Vasodilator Agents | 1993 |
Effects of nicorandil on cytosolic calcium concentrations and on tension development in the rabbit femoral artery.
Topics: Animals; Benzopyrans; Calcium; Cromakalim; Cyclic GMP; Femoral Artery; Glyburide; In Vitro Techniques; Male; Niacinamide; Nicorandil; Nitroglycerin; Norepinephrine; Potassium; Potassium Channels; Pyrroles; Rabbits; Vasodilation; Vasodilator Agents | 1994 |
Effects of K-channel openers on the contractility and electrical activity of antral circular muscle in guinea-pig stomach.
Topics: Action Potentials; Animals; Benzopyrans; Cromakalim; Glyburide; Guinea Pigs; In Vitro Techniques; Ion Channel Gating; Muscle Contraction; Muscle, Smooth; Niacinamide; Nicorandil; Potassium Channels; Pyrroles; Stomach | 1993 |
Effect of nicorandil on post-ischaemic contractile dysfunction in the heart: roles of its ATP-sensitive K+ channel opening property and nitrate property.
Topics: Adenosine Triphosphate; Animals; Glyburide; Hemodynamics; Infusions, Intravenous; Ion Channel Gating; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardial Stunning; Niacinamide; Nicorandil; Nitrates; Nitroglycerin; Potassium Channels; Premedication; Rabbits; Vasodilator Agents | 1993 |
Nicorandil as a nitrate, and cromakalim as a potassium channel opener, dilate isolated porcine large coronary arteries in an agonist-nonselective manner.
Topics: Animals; Benzopyrans; Coronary Vessels; Cromakalim; Glyburide; In Vitro Techniques; Niacinamide; Nicorandil; Nitrates; Potassium Channels; Pyrroles; Swine; Vasodilator Agents | 1993 |
Mechanism of action of KRN2391, a novel vasodilator, in canine mesenteric artery.
Topics: Animals; Arterioles; Benzopyrans; Cromakalim; Dogs; Female; Glyburide; In Vitro Techniques; Male; Mesenteric Arteries; Methylene Blue; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Pyridines; Pyrroles; Splanchnic Circulation; Vascular Resistance; Vasodilator Agents | 1993 |
Vasorelaxant mechanism of KRN2391 and nicorandil in porcine coronary arteries of different sizes.
Topics: Animals; Benzopyrans; Coronary Vessels; Cromakalim; Glyburide; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Oxyhemoglobins; Potassium Channels; Pyridines; Pyrroles; Swine; Vasodilator Agents | 1993 |
Pharmacological properties of ATP-sensitive K+ channels in mammalian skeletal muscle cells.
Topics: Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Electrophysiology; Glyburide; Guanidines; In Vitro Techniques; Mice; Muscles; Niacinamide; Nicorandil; Organic Chemicals; Pinacidil; Potassium Channels; Pyrroles; Vasodilator Agents | 1993 |
Comparative electrophysiological and mechanical actions of ATP-sensitive potassium channel openers in canine Purkinje fibers.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Dogs; Electrophysiology; Glyburide; Guanidines; In Vitro Techniques; Myocardial Contraction; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Purkinje Fibers; Pyrroles; Tetraethylammonium Compounds; Vasodilator Agents | 1993 |
Modification by cGMP of glibenclamide-sensitive K+ currents in Xenopus oocytes.
Topics: Animals; Benzopyrans; Cromakalim; Cyclic GMP; Female; Glyburide; In Vitro Techniques; Membrane Potentials; Methylene Blue; Niacinamide; Nicorandil; Nitroprusside; Oocytes; Potassium Channels; Pyridines; Pyrroles; Xenopus laevis | 1993 |
Activation by KRN2391 and nicorandil of glibenclamide-sensitive K+ channels in Xenopus oocytes.
Topics: Animals; Benzopyrans; Cromakalim; Electrophysiology; Epinephrine; Female; Glyburide; Niacinamide; Nicorandil; Oocytes; Phentolamine; Potassium Channels; Pyridines; Pyrroles; Trifluoperazine; Vasodilator Agents; Xenopus laevis | 1993 |
Relationship of severity of myocardial stunning to ATP dependent potassium channel modulation.
Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Dogs; Glyburide; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Niacinamide; Nicorandil; Potassium Channels; Vasodilator Agents | 1993 |
Activation of ATP-dependent K+ channels enhances myocardial protection due to cold high potassium cardioplegia: a force-frequency relationship study.
Topics: Animals; Cold Temperature; Glyburide; Guinea Pigs; Heart; Heart Arrest, Induced; Ion Channel Gating; Muscle Contraction; Myocardium; Niacinamide; Nicorandil; Nitroglycerin; Potassium; Potassium Channels; Vasodilator Agents | 1995 |
Preconditioning with potassium channel openers. A new concept for enhancing cardioplegic protection?
Topics: Animals; Coronary Circulation; Glyburide; Heart Arrest, Induced; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Niacinamide; Nicorandil; Potassium Channels; Rats; Rats, Wistar; Ventricular Function, Left | 1995 |
Vasodilatory effect of nicorandil on coronary arterial microvessels: its dependency on vessel size and the involvement of the ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Blood Glucose; Coronary Circulation; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Female; Glyburide; Hemodynamics; Hydrogen-Ion Concentration; Hypoglycemic Agents; Infusions, Intra-Arterial; Male; Niacinamide; Nicorandil; Potassium Channels; Vasodilator Agents | 1995 |
Endothelin-1 partially inhibits ATP-sensitive K+ current in guinea pig ventricular cells.
Topics: Action Potentials; Adenosine Triphosphate; Alkaloids; Animals; Azepines; Benzopyrans; Cromakalim; Endothelin Receptor Antagonists; Endothelins; Female; Glyburide; Guinea Pigs; Heart; Heart Ventricles; Hypoglycemic Agents; Male; Niacinamide; Nicorandil; Oligopeptides; Papillary Muscles; Potassium Channels; Protein Kinase C; Pyrroles; Staurosporine; Sulfonamides; Vasodilator Agents | 1996 |
KATP channel activation mediates nicorandil-induced relaxation of nitrate-tolerant coronary arteries.
Topics: Animals; Coronary Vessels; Dose-Response Relationship, Drug; Drug Tolerance; Glyburide; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Potassium Channels; Swine; Vasodilator Agents | 1996 |
Infarct size-reducing effect of nicorandil is mediated by the KATP channel but not by its nitrate-like properties in dogs.
Topics: Adenosine; Animals; Dogs; Female; Glyburide; Ion Channel Gating; Male; Methylene Blue; Myocardial Infarction; Myocardial Reperfusion; Myocardium; Niacinamide; Nicorandil; Nitric Oxide; Nitroglycerin; Potassium Channels; Vasodilator Agents | 1996 |
Potassium channel openers prevent potassium-induced calcium loading of cardiac cells: possible implications in cardioplegia.
Topics: Adenosine Triphosphate; Aniline Compounds; Animals; Calcium; Calcium Channel Blockers; Cardioplegic Solutions; Cells, Cultured; Fluorescent Dyes; Glyburide; Guinea Pigs; Heart Arrest, Induced; Heart Ventricles; Hypertonic Solutions; Image Processing, Computer-Assisted; Ion Channel Gating; Microscopy, Confocal; Myocardium; Niacinamide; Nicorandil; Picolines; Potassium; Potassium Channel Blockers; Potassium Channels; Pyrans; Ventricular Dysfunction; Xanthenes | 1996 |
Effects of glibenclamide and nicorandil in post-ischaemic contractile dysfunction of perfused hearts in normotensive and spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Cardiac Volume; Creatine Kinase; Glyburide; Heart Rate; Hemodynamics; Hypertension; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Niacinamide; Nicorandil; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors | 1996 |
Role of activation of ectosolic 5'-nucleotidase in the cardioprotection mediated by opening of K+c channels.
Topics: 5'-Nucleotidase; Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Dogs; Enzyme Activation; Glyburide; Heart; Hemodynamics; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Niacinamide; Nicorandil; Potassium Channels; Pyrroles; Recurrence | 1996 |
Analysis of relaxation and repolarization mechanisms of nicorandil in rat mesenteric artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Benzopyrans; Calcium Channel Blockers; Cromakalim; Electrophysiology; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Arteries; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Potassium Channels; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Rats; Rats, Sprague-Dawley; Thromboxane A2; Vasoconstrictor Agents; Vasodilator Agents | 1996 |
Nicorandil activates glibenclamide-sensitive K+ channels in smooth muscle cells of pig proximal urethra.
Topics: Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Cyclic GMP; Female; Glyburide; Membrane Potentials; Muscle, Smooth; Niacinamide; Nicorandil; Potassium Channels; Pyrroles; Swine; Urethra | 1997 |
Sulphonylurea receptor 2B and Kir6.1 form a sulphonylurea-sensitive but ATP-insensitive K+ channel.
Topics: Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Cloning, Molecular; Glyburide; Guanidines; Guanosine Diphosphate; Guanosine Triphosphate; Hypoglycemic Agents; KATP Channels; Macromolecular Substances; Magnesium; Mice; Molecular Sequence Data; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Patch-Clamp Techniques; Pinacidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sulfonylurea Compounds; Sulfonylurea Receptors; Uridine Diphosphate; Vasodilator Agents | 1997 |
Glibenclamide-induced blockade of ischemic preconditioning is time dependent in intact rat heart.
Topics: Animals; Antihypertensive Agents; Blood Glucose; Glyburide; Heart; Hemodynamics; Hypotension; Ischemic Preconditioning; Male; Myocardial Infarction; Niacinamide; Nicorandil; Rats; Rats, Wistar; Time Factors | 1997 |
Heterogeneity in the vasorelaxing effect of nicorandil on dog epicardial coronary arteries: comparison with other NO donors.
Topics: Animals; Atrial Natriuretic Factor; Benzopyrans; Coronary Vessels; Cromakalim; Cyclic GMP; Dogs; Female; Glyburide; In Vitro Techniques; Male; Methylene Blue; Molsidomine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitric Oxide; Nitroglycerin; Nitroprusside; Oxyhemoglobins; Pyrroles; Vasodilator Agents | 1997 |
Effects of nitroprusside and nicorandil on catecholamine secretion and calcium mobilization in cultured bovine adrenal chromaffin cells.
Topics: Adrenal Medulla; Animals; Calcium; Catecholamines; Cattle; Cells, Cultured; Chromaffin Cells; Glyburide; Niacinamide; Nicorandil; Nifedipine; Nitroprusside; Vasodilator Agents | 1997 |
Ventricular fibrillation in preconditioned pig hearts: role of K+ATP channels.
Topics: Action Potentials; Animals; Blood Glucose; Blood Pressure; Glyburide; Heart; Heart Rate; Ischemic Preconditioning, Myocardial; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Niacinamide; Nicorandil; Potassium Channel Blockers; Potassium Channels; Swine; Time Factors; Vasodilator Agents; Ventricular Fibrillation | 1997 |
Nicorandil reduces myocardial infarct size by opening the K(ATP) channel in rabbits.
Topics: Analysis of Variance; Animals; Blood Pressure; Dose-Response Relationship, Drug; Glyburide; Heart Rate; Linear Models; Male; Myocardial Infarction; Niacinamide; Nicorandil; Potassium Channel Blockers; Potassium Channels; Rabbits; Time Factors; Vasodilator Agents; Ventricular Fibrillation | 1997 |
Enhancement of the vasodepressor response to adenosine by nicorandil in rats: comparison with cromakalim.
Topics: Adenosine; Adenosine Triphosphate; Animals; Blood Pressure; Cromakalim; Drug Synergism; Glyburide; Heart Rate; Male; Niacinamide; Nicorandil; Potassium Channels; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 1998 |
Role of K+ channel opening and stimulation of cyclic GMP in the vasorelaxant effects of nicorandil in isolated piglet pulmonary and mesenteric arteries: relative efficacy and interactions between both pathways.
Topics: Animals; Cromakalim; Cyclic GMP; Enzyme Activation; Enzyme Inhibitors; Glyburide; Guanylate Cyclase; In Vitro Techniques; Male; Mesenteric Arteries; Niacinamide; Nicorandil; Nitroprusside; Potassium Channels; Pulmonary Artery; Swine; Vasodilator Agents; Verapamil | 1998 |
Differential role of epicardial and endocardial K(ATP) channels in potassium accumulation during regional ischemia induced by embolization of a coronary artery with latex.
Topics: Adenosine Triphosphate; Algorithms; Animals; Coronary Vessels; Dogs; Embolization, Therapeutic; Endocardium; Glyburide; Microelectrodes; Microspheres; Myocardial Ischemia; Niacinamide; Nicorandil; Pericardium; Potassium; Potassium Channel Blockers; Potassium Channels; Vasodilator Agents | 1998 |
Potentiating effect of nicorandil on the adenosine A2 receptor-mediated vasodepression in rats: potential role for KATP channels.
Topics: Adenosine; Animals; Antihypertensive Agents; Blood Pressure; Cromakalim; Dose-Response Relationship, Drug; Glyburide; Heart Rate; Injections, Intravenous; Male; Niacinamide; Nicorandil; Potassium Channels; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theobromine; Vasodilator Agents | 1998 |
Enhancement of the vasorelaxant potency of nicorandil by metabolic inhibition and adenosine in the pig coronary artery.
Topics: 2-Chloroadenosine; Animals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Coronary Vessels; Glucose; Glyburide; Hydrogen-Ion Concentration; Hypoglycemic Agents; In Vitro Techniques; Ionophores; Niacinamide; Nicorandil; Potassium Channels; Swine; Vasodilator Agents | 1998 |
Interrelationship of cardiovascular effects, plasma levels of nicorandil, and vascular cGMP formation in conscious rats.
Topics: Administration, Oral; Animals; Blood Pressure; Cyclic GMP; Glyburide; Hypoglycemic Agents; Male; Niacinamide; Nicorandil; Rats; Rats, Sprague-Dawley; Time Factors; Vasodilator Agents | 1998 |
Comparison of the potentiating effects of nicorandil and its denitrated metabolite (SG-86) on the adenosine-induced vasodepression in rats.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Drug Synergism; Glyburide; Hypoglycemic Agents; Injections, Intravenous; Male; Niacinamide; Nicorandil; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasodilator Agents | 1998 |
Nicorandil, its denitrated metabolite, SG-86 and naturally occurring vasodilators synergistically interact on adenosine-induced vasodepression in rats: special reference to adrenomedullin.
Topics: Adenosine; Adrenomedullin; Animals; Blood Pressure; Blood Vessels; Calcitonin Gene-Related Peptide; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Glyburide; Heart Rate; Hypoglycemic Agents; Infusions, Intravenous; Injections, Intravenous; Male; Niacinamide; Nicorandil; Peptides; Rats; Rats, Sprague-Dawley; Vasoactive Intestinal Peptide; Vasodilator Agents | 1999 |
Nicorandil inhibits degranulation and TNF-alpha release from RBL-2H3 cells.
Topics: Animals; beta-N-Acetylhexosaminidases; Calcium; Cell Degranulation; Cell Line; Cytoplasmic Granules; Cytosol; Dinitrophenols; Enzyme Inhibitors; Glyburide; Guanylate Cyclase; Hemoglobins; Indicators and Reagents; Mast Cells; Niacinamide; Nicorandil; Nitric Oxide; Nitric Oxide Donors; Pinacidil; Potassium; Potassium Channel Blockers; Potassium Channels; Rats; Tumor Necrosis Factor-alpha | 2002 |
Nicorandil inhibits the release of TNFalpha from a lymphocyte cell line and peripheral blood lymphocytes.
Topics: B-Lymphocytes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glyburide; Herpesvirus 4, Human; Humans; Immunoglobulin G; Leukocytes, Mononuclear; Niacinamide; Nicorandil; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Oxadiazoles; Pinacidil; Potassium Channels; Quinoxalines; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2003 |
Antidiabetic effects of dipeptidyl peptidase-IV inhibitors and sulfonylureas in streptozotocin-nicotinamide-induced mildly diabetic mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Gliclazide; Glucagon-Like Peptide 1; Glucose Intolerance; Glyburide; Hypoglycemic Agents; Insulin; Male; Mice; Mice, Inbred ICR; Niacinamide; Piperidines; Pyrrolidines; Sulfonylurea Compounds | 2009 |
Antidiabetic activity of cycloart-23-ene-3beta, 25-diol (B2) isolated from Pongamia pinnata (L. Pierre) in streptozotocin-nicotinamide induced diabetic mice.
Topics: Animals; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Glyburide; Hypoglycemic Agents; Mice; Millettia; Models, Chemical; Niacinamide; Streptozocin; Triterpenes | 2010 |
Antidiabetic activity of standardized extract of Quassia amara in nicotinamide-streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Glyburide; Hypoglycemic Agents; Male; Niacinamide; Phytotherapy; Plant Extracts; Quassia; Rats; Streptozocin; Triglycerides | 2011 |
Severe hypoglycemia due to possible interaction between glibenclamide and sorafenib in a patient with hepatocellular carcinoma.
Topics: Aged; Antineoplastic Agents; Blood Glucose; Carcinoma, Hepatocellular; Diabetes Mellitus, Type 2; Drug Interactions; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Liver Neoplasms; Male; Niacinamide; Phenylurea Compounds; Severity of Illness Index; Sorafenib | 2013 |
Antidiabetic, antihyperlipidaemic, and antioxidant activity of Syzygium densiflorum fruits in streptozotocin and nicotinamide-induced diabetic rats.
Topics: Animals; Antioxidants; Biomarkers; Blood Glucose; Cell Proliferation; Diabetes Mellitus, Experimental; Female; Fruit; Glucose Tolerance Test; Glyburide; Glycogen; Hypoglycemic Agents; Hypolipidemic Agents; Insulin-Secreting Cells; Lipid Peroxidation; Lipids; Liver; Male; Niacinamide; Oxidative Stress; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats, Wistar; Regeneration; Streptozocin; Syzygium | 2016 |
Peppermint essential oil alleviates hyperglycemia caused by streptozotocin- nicotinamide-induced type 2 diabetes in rats.
Topics: Administration, Oral; Animals; Antioxidants; Diabetes Mellitus, Type 2; Free Radical Scavengers; Glyburide; Hyperglycemia; Hypoglycemic Agents; Insulin; Liver; Mentha piperita; Niacinamide; Oxidants; Pancreas; Plant Oils; Proto-Oncogene Proteins c-bcl-2; Rats; Streptozocin | 2017 |
Betanin exhibits significant potential as an antihyperglycemic and attenuating the glycoprotein components in streptozotocin-nicotinamide-induced experimental rats.
Topics: Animals; Betacyanins; Biomarkers; Body Weight; Combined Modality Therapy; Diabetes Mellitus, Experimental; Dietary Supplements; Glyburide; Glycoproteins; Hyperglycemia; Hypoglycemic Agents; Kidney; Liver; Male; Niacinamide; Organ Specificity; Pancreas; Random Allocation; Rats, Wistar; Streptozocin | 2018 |
Effects of Combined
Topics: Animals; Aryldialkylphosphatase; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Garcinia kola; Glyburide; Hypoglycemic Agents; Insulin; Male; Metformin; Niacinamide; Plant Extracts; Rats; Rats, Wistar; Streptozocin | 2022 |
Hypoglycemic, hypolipidemic and hepatoprotective effects of
Topics: Alpinia; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glyburide; Hypoglycemic Agents; Lipids; Male; Niacinamide; Phytochemicals; Plant Extracts; Rats; Rats, Wistar; Streptozocin | 2022 |