Compounds > niacinamide

niacinamide and fk 866

niacinamide has been researched along with fk 866 in 18 studies

Research

Studies (18)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (16.67)	29.6817
2010's	14 (77.78)	24.3611
2020's	1 (5.56)	2.80

Authors

Authors	Studies
Bifulco, G; Caldarelli, A; Canonico, PL; Chini, MG; Colombano, G; Galli, U; Genazzani, AA; Sorba, G; Travelli, C; Tron, GC	1
Hasmann, M; Schemainda, I	1
Astarita, G; Kaluzova, M; Nakahata, Y; Sahar, S; Sassone-Corsi, P	1
Chiarugi, A; Formentini, L; Moroni, F	1
Bi, J; Ding, S; Li, H; Ye, SQ	1
Camacho-Pereira, J; Chini, CC; Chini, EN; Escande, C; Giri, S; Lou, Z; Matalonga, J; Nin, V	1
Felding-Habermann, B; Gay, LJ; LeBoeuf, SE; Matsuno-Yagi, A; Ritland, M; Santidrian, AF; Seo, BB; Yagi, T	1
Bam, R; Barlogie, B; Epstein, J; Khan, S; Li, X; Ling, W; Usmani, S; van Rhee, F; Venkateshaiah, SU; Yaccoby, S	1
Oblong, JE; Rovito, HA	1
Fukuwatari, T; Ito, M; Kaneko, I; Kido, S; Miyagawa, A; Miyamoto, K; Nomura, K; Sano, M; Sasaki, S; Segawa, H; Shibata, K; Shiozaki, Y; Tatsumi, S	1
Chang, YZ; Chen, MY; Hu, ML; Song, TY; Yang, NC	1
Acharya, C; Acharya, P; Adamia, S; Ballestrero, A; Bergamaschi, M; Bruzzone, S; Caffa, I; Cagnetta, A; Cea, M; Damonte, G; Fraternali, G; Garuti, A; Gobbi, M; Mastracci, L; Montecucco, F; Nencioni, A; Patrone, F; Pierri, I; Provenzani, A; Salis, A; Soncini, D; Zucal, C	1
Chen, MY; Hu, ML; Song, TY; Yang, NC; Yeh, SL	1
Bianchi, G; Bruzzone, S; Emionite, L; Magnone, M; Nahimana, A; Nencioni, A; Raffaelli, N; Raffaghello, L; Sociali, G; Sturla, L; Vigliarolo, T; Zamporlini, F	1
Baczkó, I; Blanc, J; Brenner, C; Breton, M; Decaux, JF; Deloux, R; Diguet, N; Garnier, A; Gouge, A; Gressette, M; Lavery, GG; Li, Z; Manoury, B; Mericskay, M; Mougenot, N; Piquereau, J; Tannous, C; Trammell, SAJ; Zoll, J	1
Brenner, C; Cambronne, XA; Cohen, MS; Goodman, RH; Liu, HW; Migaud, ME; Schmidt, MS; Smith, CB	1
Bellanger, S; Chin, T; Oblong, JE; Quek, LS; Rovito, HA; Tan, CL; Tan, CYR	1
Elnenaei, MO; Gujar, SA; Kennedy, BE; Reiman, A; Sadek, M	1

Other Studies

18 other study(ies) available for niacinamide and fk 866

Article	Year
A novel potent nicotinamide phosphoribosyltransferase inhibitor synthesized via click chemistry. Journal of medicinal chemistry, 2010, Jan-28, Volume: 53, Issue:2 Topics: Alkynes; Animals; Antineoplastic Agents; Autophagy; Azides; Cell Line, Tumor; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Nicotinamide Phosphoribosyltransferase; Protein Binding; Structure-Activity Relationship	2010
FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis. Cancer research, 2003, Nov-01, Volume: 63, Issue:21 Topics: Acrylamides; Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Enzyme Inhibitors; Humans; K562 Cells; Kinetics; Liver Neoplasms; Mitochondria, Liver; NAD; Niacin; Niacinamide; Nicotinamide Phosphoribosyltransferase; Oxygen Consumption; Pentosyltransferases; Piperidines	2003
Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1. Science (New York, N.Y.), 2009, May-01, Volume: 324, Issue:5927 Topics: Acrylamides; Animals; ARNTL Transcription Factors; Basic Helix-Loop-Helix Transcription Factors; Biological Clocks; Cell Line; Chromatin Assembly and Disassembly; Circadian Rhythm; CLOCK Proteins; Cytokines; Enzyme Inhibitors; Feedback, Physiological; Gene Expression Regulation; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; NAD; Niacinamide; Nicotinamide Phosphoribosyltransferase; Piperidines; Promoter Regions, Genetic; Sirtuin 1; Sirtuins; Trans-Activators; Transcription, Genetic	2009
Detection and pharmacological modulation of nicotinamide mononucleotide (NMN) in vitro and in vivo. Biochemical pharmacology, 2009, May-15, Volume: 77, Issue:10 Topics: Acetophenones; Acrylamides; Animals; Cell Survival; Chromatography, High Pressure Liquid; Cytokines; Enzyme Inhibitors; Formates; HeLa Cells; Humans; Male; Mice; NAD; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Organ Specificity; Piperidines; U937 Cells	2009
Pre-B-cell colony-enhancing factor exerts a neuronal protection through its enzymatic activity and the reduction of mitochondrial dysfunction in in vitro ischemic models. Journal of neurochemistry, 2012, Volume: 120, Issue:2 Topics: Acrylamides; Animals; Brain; Cell Death; Cells, Cultured; DNA, Mitochondrial; Embryo, Mammalian; Female; Glucose; Glutamic Acid; Hypoxia; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mitochondria; Mutation; NAD; Neurons; Neuroprotective Agents; Niacinamide; Nicotinamide Phosphoribosyltransferase; Piperidines; Pregnancy	2012
Role of deleted in breast cancer 1 (DBC1) protein in SIRT1 deacetylase activation induced by protein kinase A and AMP-activated protein kinase. The Journal of biological chemistry, 2012, Jul-06, Volume: 287, Issue:28 Topics: Acrylamides; Adaptor Proteins, Signal Transducing; Amino Acid Sequence; AMP-Activated Protein Kinases; Animals; Blotting, Western; Carbazoles; Cell Line, Tumor; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; HEK293 Cells; Hep G2 Cells; Humans; Mice; Mice, Knockout; Models, Biological; Mutation; NAD; Niacinamide; Phosphorylation; Piperidines; Resveratrol; RNA Interference; Signal Transduction; Sirtuin 1; Stilbenes	2012
Mitochondrial complex I activity and NAD+/NADH balance regulate breast cancer progression. The Journal of clinical investigation, 2013, Volume: 123, Issue:3 Topics: Acrylamides; Animals; Autophagy; Autophagy-Related Protein 5; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cytokines; Disease Progression; Electron Transport Complex I; Female; Gene Knockdown Techniques; Humans; Lung Neoplasms; Mammary Neoplasms, Experimental; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Inbred BALB C; Mice, SCID; Microtubule-Associated Proteins; Mitochondria; Multiprotein Complexes; NAD; Neoplasm Transplantation; Niacin; Niacinamide; Nicotinamide Phosphoribosyltransferase; Piperidines; Protein Transport; Proteins; Recombinant Proteins; Saccharomyces cerevisiae Proteins; TOR Serine-Threonine Kinases	2013
NAMPT/PBEF1 enzymatic activity is indispensable for myeloma cell growth and osteoclast activity. Experimental hematology, 2013, Volume: 41, Issue:6 Topics: Acrylamides; Animals; Bone and Bones; Cell Differentiation; Coculture Techniques; Cytokines; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Mice; Mice, SCID; Multiple Myeloma; NAD; Neoplasm Proteins; NF-kappa B; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Osteoclasts; Osteolysis; Piperidines; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Rabbits; Sirtuin 1; Tumor Cells, Cultured; Up-Regulation	2013
Nicotinamide preferentially protects glycolysis in dermal fibroblasts under oxidative stress conditions. The British journal of dermatology, 2013, Volume: 169 Suppl 2 Topics: Acrylamides; Adenosine Triphosphate; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Glycolysis; Humans; Hydrogen Peroxide; Niacinamide; Oxidative Phosphorylation; Oxidative Stress; Piperidines; Skin; Vitamin B Complex	2013
Hepatectomy-related hypophosphatemia: a novel phosphaturic factor in the liver-kidney axis. Journal of the American Society of Nephrology : JASN, 2014, Volume: 25, Issue:4 Topics: Acrylamides; Animals; Hepatectomy; Hypophosphatemia; Kidney; Male; Mice; Mice, Inbred C57BL; NAD; Niacinamide; Nicotinamide Phosphoribosyltransferase; Parathyroidectomy; Piperidines; Rats; Rats, Wistar; Sodium-Phosphate Cotransporter Proteins; Sodium-Phosphate Cotransporter Proteins, Type IIa	2014
Up-regulation of nicotinamide phosphoribosyltransferase and increase of NAD+ levels by glucose restriction extend replicative lifespan of human fibroblast Hs68 cells. Biogerontology, 2015, Volume: 16, Issue:1 Topics: Acrylamides; Benzamides; Cell Line; Cell Proliferation; Cell Survival; Cells, Cultured; Cellular Senescence; Cytokines; Dose-Response Relationship, Drug; Fibroblasts; Glucose; Humans; NAD; Naphthols; Niacinamide; Nicotinamide Phosphoribosyltransferase; Piperidines; Sirtuin 1; Up-Regulation	2015
APO866 Increases Antitumor Activity of Cyclosporin-A by Inducing Mitochondrial and Endoplasmic Reticulum Stress in Leukemia Cells. Clinical cancer research : an official journal of the American Association for Cancer Research, 2015, Sep-01, Volume: 21, Issue:17 Topics: Acrylamides; Adenosine Triphosphate; Aged; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Cell Line, Tumor; Cell Survival; Chromosome Aberrations; Cyclosporine; Drug Resistance, Neoplasm; Drug Synergism; Endoplasmic Reticulum Stress; Female; Gene Expression; Humans; Immunoglobulin Heavy Chains; Leukemia; Male; Membrane Potential, Mitochondrial; Middle Aged; Mitochondria; Mutation; NAD; Neoplasm Staging; Niacin; Niacinamide; Nicotinamide Phosphoribosyltransferase; Piperidines; Primary Cell Culture; Prognosis; Tumor Cells, Cultured; Unfolded Protein Response	2015
A Nampt inhibitor FK866 mimics vitamin B3 deficiency by causing senescence of human fibroblastic Hs68 cells via attenuation of NAD(+)-SIRT1 signaling. Biogerontology, 2015, Volume: 16, Issue:6 Topics: Acrylamides; AMP-Activated Protein Kinases; Cell Line; Cell Proliferation; Cellular Senescence; Cytokines; Enzyme Inhibitors; Fibroblasts; Glutathione; Humans; NAD; NADP; Niacin; Niacinamide; Nicotinamide Phosphoribosyltransferase; Piperidines; Signal Transduction; Sirtuin 1; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53	2015
Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model. Oncotarget, 2016, Jan-19, Volume: 7, Issue:3 Topics: 5'-Nucleotidase; Acrylamides; Adenosine Triphosphate; Animals; Cell Line, Tumor; Cytokines; Female; GPI-Linked Proteins; Humans; Mice; Mice, Nude; NAD; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Ovarian Neoplasms; Piperidines; Pyridinium Compounds; RNA Interference; RNA, Small Interfering	2016
Nicotinamide Riboside Preserves Cardiac Function in a Mouse Model of Dilated Cardiomyopathy. Circulation, 2018, 05-22, Volume: 137, Issue:21 Topics: Acrylamides; AMP-Activated Protein Kinases; Animals; Cardiomyopathy, Dilated; Citric Acid; Cytokines; Dietary Supplements; Disease Models, Animal; Gene Expression Profiling; Heart Failure; Metabolome; Mice; Mice, Transgenic; Myocytes, Cardiac; NAD; Niacinamide; Nicotinamide Phosphoribosyltransferase; Phosphotransferases (Alcohol Group Acceptor); Piperidines; PPAR alpha; Pyridinium Compounds; Rats; Serum Response Factor	2018
Pharmacological bypass of NAD Proceedings of the National Academy of Sciences of the United States of America, 2018, 10-16, Volume: 115, Issue:42 Topics: Acrylamides; Animals; Antineoplastic Agents, Phytogenic; Drug Combinations; Francisella tularensis; Ganglia, Spinal; NAD; Nerve Degeneration; Neurons; Niacinamide; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Piperidines; Pyridinium Compounds; Vincristine	2018
Nicotinamide Metabolism Modulates the Proliferation/Differentiation Balance and Senescence of Human Primary Keratinocytes. The Journal of investigative dermatology, 2019, Volume: 139, Issue:8 Topics: 3T3 Cells; Acrylamides; Adult; Animals; Cell Differentiation; Cell Proliferation; Cellular Senescence; Cytokines; Female; Healthy Volunteers; Humans; Keratinocytes; Mice; NAD; Niacinamide; Nicotinamide Phosphoribosyltransferase; Piperidines; Primary Cell Culture; Skin; Skin Aging; Stem Cells	2019
Targeting NAD Trends in cancer, 2020, Volume: 6, Issue:1 Topics: Acrylamides; Adenosine; Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase 1; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cytokines; Drug Synergism; Humans; Membrane Glycoproteins; Multiple Myeloma; NAD; Niacinamide; Nicotinamide Phosphoribosyltransferase; Piperidines; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Regulatory; Tumor Escape; Warburg Effect, Oncologic	2020