Compounds > niacinamide

niacinamide and fenofibrate

niacinamide has been researched along with fenofibrate in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (23.08)29.6817
2010's9 (69.23)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Ji, M; Li, Y; Lin, Q; Lin, R; Ren, F; Wang, W; Zhang, J1
Bai, L; Ji, M; Lin, R; Lu, Y; Qiao, H; Ren, F; Wang, W; Yang, L; Zhang, J1
Abdelaal, M; Abrahamsson, S; Brennan, EP; Chuah, YHD; Docherty, NG; Eckhardt, H; Elliott, JA; Fändriks, L; Fearon, N; Godson, C; Hutter, M; le Roux, CW; Malmodin, D; Martin, WP; Nair, M; Pedersen, A1
Berger, SL; Brent, M; Dang, W; Howitz, K; Jackson, B; Marmorstein, R; Sanders, BD; Schreiber, SL; Taylor, AM1
He, B; Huang, W; Li, Y; Xie, T; You, L1
He, B; Huang, W; Li, Y; Liu, J; You, L; Zhu, H1
Forgione, M; Hailu, GS; Mai, A; Robaa, D; Rotili, D; Sippl, W1
Kang, MR; Kho, JH; Kim, EJ; Um, SJ1
Biacsi, R; Kumari, D; Usdin, K1
Hadjipavlou-Litina, D; Pontiki, E1
Li, YJ; Wang, YH; Zheng, GX1

Reviews

2 review(s) available for niacinamide and fenofibrate

ArticleYear
Lysine Deacetylase Inhibitors in Parasites: Past, Present, and Future Perspectives.
    Journal of medicinal chemistry, 2017, 06-22, Volume: 60, Issue:12

    Topics: Animals; Antiparasitic Agents; Drug Repositioning; Helminth Proteins; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Leishmania; Plasmodium; Protozoan Proteins; Schistosoma; Toxoplasma; Trypanosoma

2017
Histone deacetylase inhibitors (HDACIs). Structure--activity relationships: history and new QSAR perspectives.
    Medicinal research reviews, 2012, Volume: 32, Issue:1

    Topics: Antineoplastic Agents; Benzamides; Chemical Phenomena; Fatty Acids; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydrogen Bonding; Hydroxamic Acids; Indoles; Naphthalenes; Naphthols; Niacinamide; Peptides, Cyclic; Phenylbutyrates; Pyrones; Quantitative Structure-Activity Relationship; Structure-Activity Relationship

2012

Other Studies

11 other study(ies) available for niacinamide and fenofibrate

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
PPARα agonist fenofibrate attenuates TNF-α-induced CD40 expression in 3T3-L1 adipocytes via the SIRT1-dependent signaling pathway.
    Experimental cell research, 2013, Jun-10, Volume: 319, Issue:10

    Topics: 3T3-L1 Cells; Adipocytes; AMP-Activated Protein Kinases; Animals; Benzamides; Blotting, Western; CD40 Antigens; Fenofibrate; Mice; Naphthols; NF-kappa B; Niacinamide; Oxazoles; PPAR alpha; Pyrrolidines; RNA, Messenger; Signal Transduction; Sirtuin 1; Thiocarbamates; Tumor Necrosis Factor-alpha; Tyrosine

2013
The protective effect of fenofibrate against TNF-α-induced CD40 expression through SIRT1-mediated deacetylation of NF-κB in endothelial cells.
    Inflammation, 2014, Volume: 37, Issue:1

    Topics: Acetylation; Antioxidants; Benzamides; CD40 Antigens; Cells, Cultured; Fenofibrate; Human Umbilical Vein Endothelial Cells; Humans; Hypolipidemic Agents; Inflammation; Naphthols; Niacinamide; Oxazoles; PPAR alpha; Pyrrolidines; RNA Interference; RNA, Small Interfering; Signal Transduction; Sirtuin 1; Thiocarbamates; Transcription Factor RelA; Tumor Necrosis Factor-alpha; Tyrosine; Up-Regulation

2014
Dietary restriction and medical therapy drives PPARα-regulated improvements in early diabetic kidney disease in male rats.
    Clinical science (London, England : 1979), 2022, 11-11, Volume: 136, Issue:21

    Topics: Animals; Diabetes Mellitus; Diabetic Nephropathies; Fenofibrate; Kidney; Male; Niacinamide; PPAR alpha; Rats; Rats, Sprague-Dawley; Rats, Zucker; Weight Loss

2022
Identification and characterization of novel sirtuin inhibitor scaffolds.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Drug Evaluation, Preclinical; Enzyme Inhibitors; Fibroblast Growth Factor 6; Fungal Proteins; Humans; Inhibitory Concentration 50; Kinetics; Sirtuins; Structure-Activity Relationship

2009
A FRET-based assay for screening SIRT5 specific modulators.
    Bioorganic & medicinal chemistry letters, 2015, Apr-15, Volume: 25, Issue:8

    Topics: Amino Acid Sequence; Coumarins; Enzyme Assays; Enzyme Inhibitors; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Kinetics; Molecular Sequence Data; p-Dimethylaminoazobenzene; Peptides; Sirtuins; Substrate Specificity

2015
A FRET-based assay for screening SIRT6 modulators.
    European journal of medicinal chemistry, 2015, Volume: 96

    Topics: Coumarins; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Humans; Molecular Structure; Sirtuins; Structure-Activity Relationship

2015
Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity.
    Molecular cell, 2007, Oct-26, Volume: 28, Issue:2

    Topics: Acetylation; Amino Acid Sequence; Apoptosis; Base Sequence; Cell Nucleus; Cell Proliferation; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; DNA Damage; Down-Regulation; Enzyme Inhibitors; Etoposide; G1 Phase; HCT116 Cells; HeLa Cells; Humans; Hydroxamic Acids; Molecular Sequence Data; Mutation; Naphthalenes; Niacinamide; Nuclear Proteins; Pyrones; Resting Phase, Cell Cycle; RNA Interference; RNA, Small Interfering; Sirtuin 1; Sirtuins; Transcription Factors; Transcriptional Activation; Transfection; Tumor Suppressor Protein p53

2007
SIRT1 inhibition alleviates gene silencing in Fragile X mental retardation syndrome.
    PLoS genetics, 2008, Mar-07, Volume: 4, Issue:3

    Topics: Alleles; Azacitidine; Base Sequence; Cell Line; Decitabine; DNA Methylation; DNA Primers; Enzyme Inhibitors; Female; Fragile X Mental Retardation Protein; Fragile X Syndrome; Gene Silencing; Histones; Humans; Hydroxamic Acids; Models, Biological; Mutation; Naphthalenes; Niacinamide; Promoter Regions, Genetic; Pyrones; Sirtuin 1; Sirtuins; Trinucleotide Repeat Expansion

2008
Giardia duodenalis GlSir2.2, homolog of SIRT1, is a nuclear-located and NAD(+)-dependent deacethylase.
    Experimental parasitology, 2016, Volume: 169

    Topics: Amino Acid Sequence; Benzamides; Cell Nucleus; Fluorescent Antibody Technique, Indirect; Giardia lamblia; Group III Histone Deacetylases; Humans; Inhibitory Concentration 50; Naphthalenes; Naphthols; Niacinamide; Phylogeny; Pyrones; Sequence Alignment; Sirtuins

2016