niacinamide has been researched along with ex 527 in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 12 (85.71) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| He, W; Jung, M; Maurer, B; Rumpf, T; Scharfe, M; Schmitt, ML; Sippl, W; Stolfa, DA; Verdin, E | 1 |
| Ai, T; Chen, L; Cui, H; Kamal, Z; More, SS; Wilson, DJ; Xu, Y | 1 |
| Chen, X; Go, ML; Jin, HX; Sethi, G; Yang, T | 1 |
| Bai, JJ; Cao, J; Farooqi, AS; Hong, JY; Kosciuk, T; Lin, H; Lu, X; Price, IR; Yang, M; Zhao, Q | 1 |
| Amouzegh, P; Barker, J; Curtis, R; DiStefano, PS; Flegg, A; Hamelin, E; Hixon, J; Jones, S; Kates, M; Keavey, K; McDonagh, T; Napper, AD; Navia, MA; Pons, JF; Saunders, JO; Thomas, RJ; Yau, WT | 1 |
| Caton, PW; Corder, R; Khan, NQ; Nayuni, NK; Wood, EG | 1 |
| Andersson, G; Anderstam, B; He, J; He, X; Li, Y; Lindgren, U | 1 |
| Camacho-Pereira, J; Chini, CC; Chini, EN; Escande, C; Giri, S; Lou, Z; Matalonga, J; Nin, V | 1 |
| Avner, ED; Denu, JM; Fan, LX; Li, X; Sweeney, WE; Zhou, X | 1 |
| Jarho, E; Kokkola, T; Kokkonen, P; Lahtela-Kakkonen, M; Mellini, P; Rahnasto-Rilla, M | 1 |
| Haldar, M; Mallik, S; Srivastava, DK; Yu, J | 1 |
| Bartolomé, A; Benito, M; García-Aguilar, A; Guillén, C; Nellist, M | 1 |
| Guarente, L; Igarashi, M; Jaksch, F; Kadowaki, T; Miura, M; Williams, E; Yamauchi, T | 1 |
| Alves, EGL; Araújo, FR; Bertassoli, BM; Camara, BOS; Jorge, EC; Malm, C; Ocarino, NM; Reis, AMS; Serakides, R | 1 |
14 other study(ies) available for niacinamide and ex 527
| Article | Year |
|---|---|
Inhibitors of the NAD(+)-Dependent Protein Desuccinylase and Demalonylase Sirt5.
Topics: | 2012 |
Discovery of potent and selective sirtuin 2 (SIRT2) inhibitors using a fragment-based approach.
Topics: Animals; Dogs; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; Enzyme Inhibitors; Humans; Ligands; Madin Darby Canine Kidney Cells; MCF-7 Cells; Molecular Structure; Niacinamide; Sirtuin 2; Structure-Activity Relationship; Sulfonic Acids; Suramin | 2014 |
Functionalized tetrahydro-1H-pyrido[4,3-b]indoles: a novel chemotype with Sirtuin 2 inhibitory activity.
Topics: Dose-Response Relationship, Drug; Humans; Indoles; Models, Molecular; Molecular Structure; Pyridines; Sirtuin 2; Structure-Activity Relationship | 2015 |
Novel Lysine-Based Thioureas as Mechanism-Based Inhibitors of Sirtuin 2 (SIRT2) with Anticancer Activity in a Colorectal Cancer Murine Model.
Topics: Animals; Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Disease Models, Animal; Drug Design; Drug Screening Assays, Antitumor; Female; Humans; Lysine; Male; Mice; Mice, Transgenic; Molecular Docking Simulation; Protein Isoforms; Sirtuin 2; Structure-Activity Relationship; Thiourea | 2019 |
Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1.
Topics: Animals; Biological Availability; Carbazoles; Cell Membrane Permeability; CHO Cells; Cricetinae; Cricetulus; Drug Stability; Fluorometry; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; In Vitro Techniques; Indoles; Kinetics; Mice; Mice, Inbred C57BL; Microsomes, Liver; NAD; NAD+ Nucleosidase; Niacinamide; Rats; Recombinant Proteins; Sirtuin 1; Sirtuins; Stereoisomerism; Structure-Activity Relationship | 2005 |
Fructose induces gluconeogenesis and lipogenesis through a SIRT1-dependent mechanism.
Topics: Acetyl-CoA Carboxylase; Animals; Carbazoles; Cholesterol; Fructose; Gluconeogenesis; Hepatocytes; Heterocyclic Compounds, 4 or More Rings; Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent; Lipogenesis; Male; NAD; Niacinamide; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphoenolpyruvate Carboxykinase (ATP); Rats; Rats, Sprague-Dawley; RNA-Binding Proteins; Rotenone; Sirtuin 1; Sterol Regulatory Element Binding Protein 1; Transcription Factors | 2011 |
Nicotinamide phosphoribosyltransferase (Nampt) affects the lineage fate determination of mesenchymal stem cells: a possible cause for reduced osteogenesis and increased adipogenesis in older individuals.
Topics: Adipocytes; Adipogenesis; Aging; Animals; Bone Marrow Cells; Carbazoles; Cell Line; Cell Lineage; Culture Media; Cytokines; Humans; Intracellular Space; Male; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; NAD; Niacinamide; Nicotinamide Phosphoribosyltransferase; Osteogenesis; Sirtuin 1; Stromal Cells | 2011 |
Role of deleted in breast cancer 1 (DBC1) protein in SIRT1 deacetylase activation induced by protein kinase A and AMP-activated protein kinase.
Topics: Acrylamides; Adaptor Proteins, Signal Transducing; Amino Acid Sequence; AMP-Activated Protein Kinases; Animals; Blotting, Western; Carbazoles; Cell Line, Tumor; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; HEK293 Cells; Hep G2 Cells; Humans; Mice; Mice, Knockout; Models, Biological; Mutation; NAD; Niacinamide; Phosphorylation; Piperidines; Resveratrol; RNA Interference; Signal Transduction; Sirtuin 1; Stilbenes | 2012 |
Sirtuin 1 inhibition delays cyst formation in autosomal-dominant polycystic kidney disease.
Topics: Acetylation; Animals; Apoptosis; Carbazoles; Cell Proliferation; Cells, Cultured; Drug Evaluation, Preclinical; Epithelial Cells; Female; Gene Expression Regulation, Enzymologic; Kidney; Male; Mice; Mice, Knockout; Niacinamide; Phosphorylation; Polycystic Kidney, Autosomal Dominant; Protein Kinase C; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-myc; Retinoblastoma Protein; Sirtuin 1; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53 | 2013 |
Studying SIRT6 regulation using H3K56 based substrate and small molecules.
Topics: Acetylation; Carbazoles; Histones; Humans; Molecular Structure; Niacinamide; Peptides; Quercetin; Recombinant Proteins; Sirtuins; Structure-Activity Relationship | 2014 |
Role of the Substrate Specificity-Defining Residues of Human SIRT5 in Modulating the Structural Stability and Inhibitory Features of the Enzyme.
Topics: Amino Acids; Biocatalysis; Calorimetry; Carbazoles; Catalytic Domain; Circular Dichroism; Enzyme Stability; Humans; Kinetics; Models, Molecular; Mutant Proteins; Mutation; Niacinamide; Protein Denaturation; Protein Structure, Secondary; Sirtuin 1; Sirtuins; Structure-Activity Relationship; Substrate Specificity; Temperature | 2016 |
TSC2 N-terminal lysine acetylation status affects to its stability modulating mTORC1 signaling and autophagy.
Topics: Acetylation; Animals; Autophagy; Carbazoles; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; HEK293 Cells; Histone Deacetylase Inhibitors; Humans; Lysine; Mechanistic Target of Rapamycin Complex 1; Mice; Multiprotein Complexes; Niacinamide; Protein Domains; Protein Processing, Post-Translational; Protein Stability; Resveratrol; RNA Interference; Signal Transduction; Sirtuin 1; Stilbenes; Time Factors; TOR Serine-Threonine Kinases; Transfection; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins | 2016 |
NAD
Topics: Adult Stem Cells; Aging; Animals; Carbazoles; Cell Proliferation; Cells, Cultured; Dextran Sulfate; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; NAD; Niacinamide; Pyridinium Compounds; Rejuvenation; Sirolimus | 2019 |
Differentiation of canine adipose mesenchymal stem cells into insulin-producing cells: comparison of different culture medium compositions.
Topics: Adipogenesis; Animals; Carbazoles; Cell Differentiation; Chondrogenesis; Culture Media; Dogs; Immunophenotyping; Insulin; Mercaptoethanol; Mesenchymal Stem Cells; Niacinamide; Osteogenesis | 2021 |