niacinamide has been researched along with dibutyl phthalate in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (29.17) | 29.6817 |
| 2010's | 16 (66.67) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Atkins, AR; Beresford, IJ; Brackenborough, K; Briggs, MA; Calver, AR; Cilia, J; Cluderay, JE; Crook, B; Davis, JB; Davis, RK; Davis, RP; Dawson, LA; Foley, AG; Gartlon, J; Gonzalez, MI; Heslop, T; Hirst, WD; Jennings, C; Jones, DN; Lacroix, LP; Martyn, A; Medhurst, AD; Ociepka, S; Ray, A; Regan, CM; Roberts, JC; Schogger, J; Southam, E; Stean, TO; Trail, BK; Upton, N; Wadsworth, G; Wald, JA; White, T; Wilson, DM; Witherington, J; Woolley, ML; Worby, A | 1 |
| Herrmann, M; Huber, R; Klein, T; Postius, S; Senn-Bilfinger, J; Shin, JM; Simon, WA | 1 |
| Billinton, A; Bingham, S; Brass, A; Chessell, IP; Collins, SD; Dalziel, RG; Medhurst, AD; Medhurst, SJ; Roberts, JC | 1 |
| Brown, SH; Chen, CP; Lai, MK; Lee, J; Medhurst, AD; Roberts, JC; Roman, S | 1 |
| Anaclet, C; Brown, SH; Buda, C; Feng, JQ; Franco, P; Guidon, G; Guo, RX; Lin, JS; Medhurst, AD; Parmentier, R; Roberts, JC; Sastre, JP; Upton, N; Zhang, M | 1 |
| Barry, C; Foley, AG; Medhurst, AD; Prendergast, A; Regan, CM; Scully, D; Upton, N | 1 |
| Ballini, C; Blandina, P; Corte, LD; Giannoni, P; Giovannini, MG; Medhurst, AD; Passani, MB | 1 |
| Bender, D; Cunningham, VJ; Gee, AD; Gunn, RN; Laruelle, M; Medhurst, AD; Plisson, C; Roberts, JC; Salinas, CA | 1 |
| Ashworth, S; Comley, RA; Cunningham, VJ; Gee, AD; Gunn, RN; Lai, RY; Laruelle, M; Plisson, C; Rabiner, EA; Wilson, AA | 1 |
| Slifstein, M | 1 |
| Brioni, JD; Chandran, P; Cowart, MD; Decker, MW; Esbenshade, TA; Honore, P; Hsieh, GC; Liu, H; Pai, M; Salyers, AK; Wensink, EJ; Wetter, JM; Zhao, C | 1 |
| Browning, C; Clark, KL; Connor, HE; Ford, AJ; Hall, DA; Hodgson, ST; Luttmann, MA; Russell, LJ; Saunders, KA; Slack, RJ | 1 |
| Carruthers, NI; Carter, P; Fowler, JS; Jiang, X; King, P; Letavic, MA; Logan, J; Muench, L; Sands, S; Shea, C; Xu, Y | 1 |
| Brown-Proctor, C; Gao, M; Glick-Wilson, BE; Hutchins, GD; Shekhar, A; Steele, BL; Wang, M; Zheng, QH | 1 |
| Brioni, JD; Chu, KL; Cowart, MD; McGaraughty, S | 1 |
| Boström, E; Halldin, C; Jostell, KG; Jucaite, A; Nyberg, S; Segerdahl, M; Stenkrona, P; Takano, A | 1 |
| Carson, RE; Gunn, RN; Huang, Y; Labaree, D; Rabiner, EA; Ropchan, J; Salinas, C; Searle, G; Weinzimmer, D | 1 |
| Apps, J; Bailey, N; Bamford, MJ; Beresford, IJ; Brackenborough, K; Briggs, MA; Brough, S; Calver, AR; Crook, B; Davis, RK; Davis, RP; Davis, S; Dean, DK; Harris, L; Heslop, T; Holland, V; Jeffrey, P; Medhurst, AD; Panchal, TA; Parr, CA; Quashie, N; Schogger, J; Sehmi, SS; Steadman, JG; Stean, TO; Takle, AK; Trail, B; Wald, J; Wilson, DM; Witherington, J; Worby, A | 1 |
| Ashworth, S; Berges, A; Boardley, R; Comley, RA; Cunningham, VJ; Gunn, RN; Lai, RY; Laruelle, M; Rabiner, EA; Searle, G; Wilson, AA | 1 |
| Camussi, G; Chazot, PL; Grange, C; Lanzi, C; Moggio, A; Pini, A; Rosa, AC; Veglia, E | 1 |
| Ahlgren, C; Amini, N; Brown, DG; Farde, L; Finnema, SJ; Häggkvist, J; Johnström, P; Jureus, A; Malmquist, J; Nakao, R; Nilsson, M; Schou, M; Takano, A; Tari, L; Throner, SR; Varnäs, K; Wesolowski, SS | 1 |
| Chazot, PL; Lethbridge, NL | 1 |
| Cachope, R; Colwell, CS; Loh, DH; Wang, HB; Whittaker, DS | 1 |
| Attia, K; de Vries, EFJ; Dierckx, RAJO; Doorduin, J; Elsinga, PH; Ghazanfari, N; Heeres, A; Koelewijn, M; Kominia, M; Sijbesma, JWA; van Waarde, A; Visser, TJ; Willemsen, ATM | 1 |
2 trial(s) available for niacinamide and dibutyl phthalate
| Article | Year |
|---|---|
AZD5213: a novel histamine H3 receptor antagonist permitting high daytime and low nocturnal H3 receptor occupancy, a PET study in human subjects.
Topics: Adult; Autoradiography; Benzazepines; Brain; Carbon Radioisotopes; Circadian Rhythm; Dose-Response Relationship, Drug; Histamine H3 Antagonists; Humans; Male; Niacinamide; Positron-Emission Tomography; Protein Binding; Radioligand Assay; Receptors, Histamine H3; Young Adult | 2013 |
Unexpectedly high affinity of a novel histamine H(3) receptor antagonist, GSK239512, in vivo in human brain, determined using PET.
Topics: Adult; Benzazepines; Brain; Histamine Antagonists; Humans; Male; Middle Aged; Niacinamide; Positron-Emission Tomography; Radiopharmaceuticals; Receptors, Histamine H3 | 2014 |
22 other study(ies) available for niacinamide and dibutyl phthalate
| Article | Year |
|---|---|
GSK189254, a novel H3 receptor antagonist that binds to histamine H3 receptors in Alzheimer's disease brain and improves cognitive performance in preclinical models.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Animals; Benzazepines; Binding, Competitive; Brain; Cell Line; Dogs; Histamine Agonists; Histamine Antagonists; Humans; Male; Maze Learning; Mice; Middle Aged; Neurotransmitter Agents; Niacinamide; Nootropic Agents; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Histamine H3; Sus scrofa | 2007 |
Soraprazan: setting new standards in inhibition of gastric acid secretion.
Topics: Animals; Anti-Ulcer Agents; Benzazepines; Dogs; Enzyme Inhibitors; Esomeprazole; Gastric Acid; Gastric Mucosa; Gene Expression; H(+)-K(+)-Exchanging ATPase; Humans; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Male; Molecular Structure; Naphthyridines; Niacinamide; Nigericin; Potassium; Proton Pump Inhibitors; Rabbits; Sodium-Potassium-Exchanging ATPase; Stomach; Swine | 2007 |
Novel histamine H3 receptor antagonists GSK189254 and GSK334429 are efficacious in surgically-induced and virally-induced rat models of neuropathic pain.
Topics: Animals; Azepines; Benzazepines; Disease Models, Animal; Herpes Zoster; Histamine H3 Antagonists; Humans; Male; Neuralgia; Niacinamide; Pain Measurement; Pain, Postoperative; Pyridines; Rats; Receptors, Histamine H3; Spinal Cord; Tissue Distribution | 2008 |
Characterization of histamine H3 receptors in Alzheimer's Disease brain and amyloid over-expressing TASTPM mice.
Topics: Aged; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Autoradiography; Benzazepines; Brain; Female; Histamine H3 Antagonists; Humans; Male; Mice; Mice, Transgenic; Mutation; Neocortex; Niacinamide; Radioligand Assay; Receptors, Histamine H3; Severity of Illness Index | 2009 |
Differential effects of acute and repeat dosing with the H3 antagonist GSK189254 on the sleep-wake cycle and narcoleptic episodes in Ox-/- mice.
Topics: Animals; Autoradiography; Benzazepines; Benzhydryl Compounds; Brain; Dose-Response Relationship, Drug; Electroencephalography; Electromyography; Histamine H3 Antagonists; Intracellular Signaling Peptides and Proteins; Mice; Mice, Knockout; Modafinil; Narcolepsy; Neuropeptides; Niacinamide; Orexins; Radioligand Assay; Receptors, Histamine H3; Sleep; Wakefulness | 2009 |
H3 receptor antagonism enhances NCAM PSA-mediated plasticity and improves memory consolidation in odor discrimination and delayed match-to-position paradigms.
Topics: Amnesia; Animals; Benzazepines; Brain; Cell Survival; Discrimination Learning; Dose-Response Relationship, Drug; Histamine H3 Antagonists; Male; Maze Learning; Memory; Neural Cell Adhesion Molecules; Neurogenesis; Neuronal Plasticity; Neurons; Neuropsychological Tests; Niacinamide; Olfactory Perception; Rats; Rats, Wistar; Scopolamine; Time Factors | 2009 |
Regional differential effects of the novel histamine H3 receptor antagonist 6-[(3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-N-methyl-3-pyridinecarboxamide hydrochloride (GSK189254) on histamine release in the central nervous system of freely
Topics: Acetylcholine; Animals; Behavior, Animal; Benzazepines; Brain; Cognition; Dopamine; Histamine H3 Antagonists; Histamine Release; Hypothalamic Area, Lateral; Male; Memory, Short-Term; Microdialysis; Motor Activity; Neurons; Niacinamide; Perfusion; Rats; Rats, Sprague-Dawley; Receptors, Histamine H3 | 2010 |
11C-GSK189254: a selective radioligand for in vivo central nervous system imaging of histamine H3 receptors by PET.
Topics: Animals; Autoradiography; Benzazepines; Brain; Carbon Radioisotopes; Central Nervous System; Female; Humans; Hydrophobic and Hydrophilic Interactions; Isotope Labeling; Kinetics; Ligands; Molecular Imaging; Niacinamide; Positron-Emission Tomography; Radiochemistry; Receptors, Histamine H3; Swine; Tritium | 2009 |
Evaluation of 11C-GSK189254 as a novel radioligand for the H3 receptor in humans using PET.
Topics: Adult; Aged; Algorithms; Benzazepines; Biotransformation; Brain; Carbon Radioisotopes; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Models, Statistical; Niacinamide; Positron-Emission Tomography; Radiopharmaceuticals; Receptors, Histamine H3; Reproducibility of Results | 2010 |
When reversible ligands do not reverse, and other modelers' dilemmas.
Topics: Benzazepines; Ligands; Models, Structural; Nervous System; Niacinamide; Positron-Emission Tomography; Radiopharmaceuticals; Receptors, Drug; Receptors, Histamine H3; Reference Standards; Tomography, Emission-Computed, Single-Photon | 2010 |
Antinociceptive effects of histamine H3 receptor antagonist in the preclinical models of pain in rats and the involvement of central noradrenergic systems.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Benzazepines; Dose-Response Relationship, Drug; Formaldehyde; Hand Strength; Histamine H3 Antagonists; Injections, Spinal; Male; Motor Activity; Neurons; Niacinamide; Norepinephrine; Pain; Pain Measurement; Pain Perception; Phentolamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H3 | 2010 |
Pharmacological characterization of GSK1004723, a novel, long-acting antagonist at histamine H(1) and H(3) receptors.
Topics: Allergens; Animals; Benzazepines; Binding, Competitive; Bronchi; Bronchial Provocation Tests; Bronchoconstriction; Carbachol; Cell Line; CHO Cells; Cricetinae; Cricetulus; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine H3 Antagonists; Humans; In Vitro Techniques; Niacinamide; Ovalbumin; Phthalazines; Piperidines; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H3; Recombinant Proteins; Rhinitis, Allergic, Perennial; Transfection | 2011 |
Blockade of the brain histamine H3 receptor by JNJ-39220675: preclinical PET studies with [¹¹C]GSK189254 in anesthetized baboon.
Topics: Administration, Oral; Animals; Azepines; Benzazepines; Blood-Brain Barrier; Brain; Dose-Response Relationship, Drug; Female; Histamine H3 Antagonists; Injections, Intravenous; Niacinamide; Papio; Positron-Emission Tomography; Pyridines; Radiopharmaceuticals; Receptors, Histamine H3; Sensitivity and Specificity; Time Factors; Tissue Distribution | 2012 |
A new facile synthetic route to [11C]GSK189254, a selective PET radioligand for imaging of CNS histamine H3 receptor.
Topics: Benzazepines; Carbon Isotopes; Molecular Structure; Niacinamide; Positron-Emission Tomography; Radioligand Assay; Receptors, Histamine H3 | 2012 |
Antagonism of supraspinal histamine H3 receptors modulates spinal neuronal activity in neuropathic rats.
Topics: Animals; Benzazepines; Histamine H3 Antagonists; Locus Coeruleus; Male; Neuralgia; Neurons; Niacinamide; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Receptors, Histamine H3; Spinal Cord | 2012 |
Kinetic analysis of drug-target interactions with PET for characterization of pharmacological hysteresis.
Topics: Algorithms; Animals; Benzazepines; Brain; Computer Simulation; Female; Histamine H3 Antagonists; Kinetics; Models, Biological; Niacinamide; Papio; Positron-Emission Tomography | 2013 |
Identification of clinical candidates from the benzazepine class of histamine H3 receptor antagonists.
Topics: Animals; Benzazepines; Dogs; Half-Life; Haplorhini; Histamine H3 Antagonists; Humans; Male; Microsomes, Liver; Niacinamide; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Histamine H3; Structure-Activity Relationship | 2013 |
Histamine receptor expression in human renal tubules: a comparative pharmacological evaluation.
Topics: Benzazepines; Cell Line; Chlorpheniramine; Dose-Response Relationship, Drug; Epithelial Cells; Histamine; Histamine Antagonists; Humans; In Vitro Techniques; Indoles; Kidney Tubules; Niacinamide; Piperazines; Ranitidine; Receptors, Histamine; Second Messenger Systems | 2015 |
Discovery and Preclinical Validation of [(11)C]AZ13153556, a Novel Probe for the Histamine Type 3 Receptor.
Topics: Alzheimer Disease; Animals; Autoradiography; Benzamides; Benzazepines; Brain; Carbon Radioisotopes; Dose-Response Relationship, Drug; Female; Guinea Pigs; Haplorhini; Histamine Agents; Humans; Male; Mice; Mice, Inbred C57BL; Niacinamide; Piperazines; Protein Binding; Rats; Receptors, Histamine H3; Reproducibility of Results; Time Factors; Tissue Distribution; Tritium | 2016 |
Ligand autoradiographical quantification of histamine H
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Autoradiography; Benzazepines; Cerebellar Cortex; Dementia; Depression; Female; Globus Pallidus; Hallucinations; Humans; Lewy Body Disease; Ligands; Male; Middle Aged; Niacinamide; Receptors, Histamine H3 | 2016 |
Possible use of a H3R antagonist for the management of nonmotor symptoms in the Q175 mouse model of Huntington's disease.
Topics: Animals; Benzazepines; Cognition; Disease Models, Animal; Drug Administration Schedule; Histamine H3 Antagonists; Humans; Huntington Disease; Male; Maze Learning; Mice; Motor Activity; Niacinamide; Receptors, Histamine H3 | 2017 |
Pharmacokinetic Modeling of [
Topics: Animals; Benzazepines; Brain; Carrier Proteins; Histamine; Neurodegenerative Diseases; Niacinamide; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Wistar | 2022 |