niacinamide has been researched along with alpha-aminopyridine in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (35.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 10 (50.00) | 24.3611 |
| 2020's | 2 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kato, A; Nakamura, F; Sugimoto, T; Sumino, S; Tomaru, T; Uchida, Y | 1 |
| Sugimoto, T; Uchida, Y | 1 |
| Coldwell, MC; Cooper, SM; Hamilton, TC; Howlett, DR; Wilson, C | 1 |
| Kuromaru, O; Sakai, K | 1 |
| Kigoshi, S; Muramatsu, I; Nishio, M | 1 |
| Uchida, Y | 1 |
| Higuchi, M; Rokutanda, M; Sakanashi, M; Takeo, S | 1 |
| Molliver, ME; O'Hearn, E | 1 |
| Bonar, SL; Brustkern, SJ; Chen, NX; Christine, L; Heier, RF; Hu, Y; Huang, HC; Kishore, NN; Kurumbail, RG; Lennon, PJ; Li, X; Mathialagan, S; Poda, GI; Reding, MT; Selness, SR; Sommers, CD; Venkatraman, N; Wolfson, SG; Xie, J | 1 |
| Ai, J; Geng, M; Ji, Y; Jiang, H; Li, C; Liang, Z; Liu, H; Luo, C; Peng, X; Zhang, D | 1 |
| de Gramont, A; Dos Santos, C; Faivre, S; Raymond, E; Riveiro, ME; Serova, M; Slimane, K; Tijeras-Raballand, A | 1 |
| Fan, L; Han, TT; Li, JY; Xu, W | 1 |
| Beyene, J; Danska, JS; Grandal, I; Guidos, CJ; Hitzler, JK; Kowalski, PE; Matei, IR; Minden, MD; Nutter, LM; Papp, E; Perova, T | 1 |
| Galanis, A; Levis, M | 1 |
| Dou, H; Feng, K; Jiang, X; Li, Z; Wang, T; Zhang, Y; Zhou, F | 1 |
| Eriksson, LA; Gao, C; Grøtli, M | 1 |
| Acharya, BN; Acharya, J; Bhalerao, U; Karade, HN; Raviraju, G; Valiveti, AK | 1 |
| An, M; Cai, Z; Huang, X; Jiang, Y; Li, R; Ni, T; Xie, F; Zang, C; Zhang, D; Zhao, J | 1 |
| Bang, YJ; Bendell, J; Carlsen, M; Chow, KH; Chung, HC; de Miguel, MJ; Gandhi, L; Italiano, A; Lin, CC; Patnaik, A; Schmidt, S; Su, WC; Szpurka, AM; Vangerow, B; Xu, X; Yap, TA; Yu, D; Zhao, Y | 1 |
| D'Ursi, P; Ford, RC; Fossa, P; Meng, X; Milanesi, M; Orro, A; Padoan, R; Pedemonte, N; Pesce, E; Rondina, A; Rusnati, M; Uggeri, M; Urbinati, C | 1 |
1 review(s) available for niacinamide and alpha-aminopyridine
| Article | Year |
|---|---|
Role of chemokines and their receptors in chronic lymphocytic leukemia: function in microenvironment and targeted therapy.
Topics: Aminopyridines; Antineoplastic Agents; Benzylamines; Chemokine CXCL12; Clinical Trials as Topic; Cyclams; Dasatinib; Heterocyclic Compounds; Humans; Lenalidomide; Leukemia, Lymphocytic, Chronic, B-Cell; Molecular Targeted Therapy; Morpholines; Niacinamide; Oxazines; Phenylurea Compounds; Protein Kinase Inhibitors; Purines; Pyridines; Pyrimidines; Quinazolinones; Receptors, CXCR4; Sorafenib; Thalidomide; Thiazoles; Tumor Microenvironment | 2014 |
1 trial(s) available for niacinamide and alpha-aminopyridine
| Article | Year |
|---|---|
Safety and Clinical Activity of a New Anti-PD-L1 Antibody as Monotherapy or Combined with Targeted Therapy in Advanced Solid Tumors: The PACT Phase Ia/Ib Trial.
Topics: Adult; Aged; Aged, 80 and over; Aminopyridines; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; B7-H1 Antigen; Benzimidazoles; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Indazoles; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Niacinamide; Prognosis; Ramucirumab | 2021 |
18 other study(ies) available for niacinamide and alpha-aminopyridine
| Article | Year |
|---|---|
Phasic contractions of canine and human coronary arteries induced by potassium channel blockers.
Topics: 4-Aminopyridine; Adult; Aged; Amifampridine; Aminopyridines; Angina Pectoris, Variant; Animals; Arteries; Coronary Vasospasm; Coronary Vessels; Dogs; Female; Humans; Ion Channels; Macaca mulatta; Male; Middle Aged; Models, Biological; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Swine; Tetraethylammonium Compounds; Vasoconstriction | 1986 |
The effects of nicorandil on phasic contractions of isolated canine coronary artery.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Calmodulin; Coronary Vessels; Dogs; Ergonovine; In Vitro Techniques; Membrane Potentials; Muscle Contraction; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Vasodilator Agents | 1987 |
Comparative effects of K+ channel blockade on the vasorelaxant activity of cromakalim, pinacidil and nicorandil.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Benzopyrans; Cardiovascular Agents; Cromakalim; Guanidines; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Procaine; Pyrroles; Rabbits; Rubidium Radioisotopes; Tetraethylammonium Compounds; Vasodilator Agents | 1988 |
Effects of nicorandil on the rhythmic contractile response of isolated miniature pig coronary artery to 3,4-diaminopyridine: comparison with nitroglycerin.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Coronary Vasospasm; Coronary Vessels; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Swine; Swine, Miniature | 1986 |
Mechanisms of tetraethylammonium-induced contraction in the canine coronary artery.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Cesium; Chlorides; Coronary Vessels; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Phenylephrine; Potassium; Tetraethylammonium Compounds; Vasodilator Agents; Verapamil | 1986 |
Decreasing potassium conductance--a possible mechanism of phasic coronary vasospasm.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Calcium; Coronary Vasospasm; Coronary Vessels; Dogs; Ergonovine; Female; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Macaca mulatta; Male; Membrane Potentials; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardium; Niacinamide; Nicorandil; Nifedipine; Potassium; Swine; Tetraethylammonium; Tetraethylammonium Compounds | 1985 |
Effects of 4-aminopyridine and tetraethylammonium on relaxant responses of isolated dog coronary arteries to 2-nicotinamidoethyl nitrate (SG-75).
Topics: 4-Aminopyridine; Aminopyridines; Animals; Coronary Vessels; Dinoprost; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Niacinamide; Nicorandil; Nitrates; Potassium; Prostaglandins F; Tetraethylammonium Compounds; Vasoconstriction | 1982 |
The olivocerebellar projection mediates ibogaine-induced degeneration of Purkinje cells: a model of indirect, trans-synaptic excitotoxicity.
Topics: Aminopyridines; Animals; Behavior, Animal; Cell Death; Cerebellar Cortex; Hallucinogens; Harmaline; Ibogaine; Immunohistochemistry; Male; Microglia; Nerve Degeneration; Neural Pathways; Neurotoxins; Niacinamide; Olivary Nucleus; Purkinje Cells; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 1997 |
Aminopyridinecarboxamide-based inhaled IKK-2 inhibitors for asthma and COPD: Structure-activity relationship.
Topics: Administration, Inhalation; Aminopyridines; Asthma; Binding, Competitive; Drug Design; HEK293 Cells; Humans; I-kappa B Kinase; Indazoles; Isonicotinic Acids; Microsomes, Liver; Models, Molecular; Molecular Structure; Molecular Targeted Therapy; Niacinamide; Phenethylamines; Potassium Channel Blockers; Protein Kinase Inhibitors; Pulmonary Disease, Chronic Obstructive; Pyrazoles; Structure-Activity Relationship; Sulfonamides | 2011 |
Discovery of novel 2-aminopyridine-3-carboxamides as c-Met kinase inhibitors.
Topics: Aminopyridines; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Structure; Niacinamide; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Structure-Activity Relationship | 2012 |
Benchmarking effects of mTOR, PI3K, and dual PI3K/mTOR inhibitors in hepatocellular and renal cell carcinoma models developing resistance to sunitinib and sorafenib.
Topics: Aminopyridines; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Carcinoma, Hepatocellular; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Everolimus; Humans; Imidazoles; Indoles; Kidney Neoplasms; Liver Neoplasms; Mechanistic Target of Rapamycin Complex 1; Morpholines; Multiprotein Complexes; Niacinamide; Phenylurea Compounds; Phosphoinositide-3 Kinase Inhibitors; Pyrimidines; Pyrroles; Quinolines; Signal Transduction; Sirolimus; Sorafenib; Sunitinib; TOR Serine-Threonine Kinases | 2013 |
Therapeutic potential of spleen tyrosine kinase inhibition for treating high-risk precursor B cell acute lymphoblastic leukemia.
Topics: Administration, Oral; Adult; Aminopyridines; Animals; Cell Proliferation; Cell Survival; Child; Female; Humans; Intracellular Signaling Peptides and Proteins; Leukemia; Male; Mice; Mice, SCID; Morpholines; Mutation; Neoplasm Transplantation; Niacinamide; Oligonucleotide Array Sequence Analysis; Oxazines; Phosphorylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cells, B-Lymphoid; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Recurrence; Signal Transduction; Spleen; Syk Kinase; Treatment Outcome | 2014 |
Inhibition of c-Kit by tyrosine kinase inhibitors.
Topics: Aminopyridines; Antineoplastic Agents; Benzothiazoles; Biomarkers; Bone Marrow; Cell Line, Tumor; Clinical Trials as Topic; Dasatinib; fms-Like Tyrosine Kinase 3; Gene Expression; Hair; Hematopoietic Stem Cells; Humans; Indazoles; Leukemia, Myeloid, Acute; Niacinamide; Phenylurea Compounds; Pigmentation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sorafenib; Sulfonamides; Thiazoles | 2015 |
Sorafenib and DE605, a novel c-Met inhibitor, synergistically suppress hepatocellular carcinoma.
Topics: Aminopyridines; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzoxazoles; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Liver Neoplasms; Mice; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Real-Time Polymerase Chain Reaction; Sorafenib; Transfection; Xenograft Model Antitumor Assays | 2015 |
Characterization of interactions and pharmacophore development for DFG-out inhibitors to RET tyrosine kinase.
Topics: Aminopyridines; Binding Sites; Humans; Indoles; Kinetics; Molecular Docking Simulation; Molecular Dynamics Simulation; Naphthalenes; Niacinamide; Oligonucleotides; Phenylurea Compounds; Protein Binding; Protein Conformation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-ret; Pyrazoles; Sorafenib; Structural Homology, Protein; Thermodynamics; Vascular Endothelial Growth Factor Receptor-2 | 2015 |
Synthesis and in vitro reactivation study of isonicotinamide derivatives of 2-(hydroxyimino)-N-(pyridin-3-yl)acetamide as reactivators of Sarin and VX inhibited human acetylcholinesterase (hAChE).
Topics: Acetamides; Aminopyridines; Cholinesterase Inhibitors; Cholinesterase Reactivators; Erythrocyte Membrane; Humans; Kinetics; Niacinamide; Obidoxime Chloride; Organothiophosphorus Compounds; Oximes; Pralidoxime Compounds; Sarin | 2016 |
Synthesis and Biological Evaluation of Novel 2-Aminonicotinamide Derivatives as Antifungal Agents.
Topics: Aminopyridines; Antifungal Agents; Candida; Candida albicans; Cryptococcus neoformans; Drug Resistance, Fungal; Isoxazoles; Microbial Sensitivity Tests; Microscopy, Confocal; Microscopy, Electron; Niacinamide; Structure-Activity Relationship | 2017 |
Virtual Drug Repositioning as a Tool to Identify Natural Small Molecules That Synergize with Lumacaftor in F508del-CFTR Binding and Rescuing.
Topics: Aminopyridines; Benzodioxoles; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Repositioning; Humans; Mutation; Niacinamide; Proteasome Endopeptidase Complex; Ubiquitins | 2022 |