niacinamide and alloxan

niacinamide has been researched along with alloxan in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199018 (62.07)18.7374
1990's5 (17.24)18.2507
2000's1 (3.45)29.6817
2010's4 (13.79)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Gunnarsson, R1
Amherdt, M; Malaisse, WJ; Malaisse-Lagae, F; Orci, L; Perrelet, A; Ravazzola, M; Renold, AE1
Kass, GE; Meier, P; Richter, C; Schlegel, J1
Meier, P; Richter, C1
Pipeleers, D; Van de Winkel, M1
Forbes, PM; Hall, CR; LeDoux, SP; Patton, NJ; Wilson, GL1
Miwa, A; Okamoto, H; Takasawa, S; Yamagami, T; Yamamoto, H1
Frei, B; Richter, C; Winterhalter, KH1
Lauschke, H; Rudolph, G1
Dean, PM; Matthews, EK1
Falany, J; Fischer, LJ; Fisher, R1
Sandler, S; Swenne, I1
Andersson, A; Sandler, S; Welsh, M1
McCord, JM; Mossman, BT; Mullins, DW; Patton, NJ; Wilson, GL1
Baba, S; Kazumi, T; Yoshino, G1
Okamoto, H; Uchigata, Y; Yamamoto, H1
Kawamura, A; Okamoto, H; Uchigata, Y; Yamamoto, H1
Kashiwada, J; Kato, Y; Kawaguchi, M; Seino, Y; Tamura, K; Tanigawa, K1
Andersson, A; Korsgren, O; Sandler, S1
Ashford, ML; Herson, PS1
Bloch, K; Bloch, O; Harel, A; Vardi, P1
ARAZ, A; ESER, S; TEKMAN, S2
CURLEY, FJ; INGALLS, TH; INGENITO, EF1
Bahrami, AR; Matin, MM; Moghimi, A; Neshati, Z1
Islam, MS; Wilson, RD1
Kamarul, T; Murali, MR; Raghavendran, H; Savatey, H; Vattam, KK1
Abdullah, KM; Alam, MM; Iqbal, Z; Naseem, I1
Ahmad, R; Bari, DG; Gaur, R; Gautam, GK; Parveen, K; Rais, N; Shukla, KS; Singh, AP; Ved, A1

Reviews

1 review(s) available for niacinamide and alloxan

ArticleYear
Model of Streptozotocin-nicotinamide Induced Type 2 Diabetes: a Comparative Review.
    Current diabetes reviews, 2022, Volume: 18, Issue:8

    Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Humans; NAD; Niacinamide; Poly(ADP-ribose) Polymerases; Rats; Streptozocin

2022

Other Studies

28 other study(ies) available for niacinamide and alloxan

ArticleYear
Inhibition of insulin biosynthesis by alloxan, streptozotocin, and N-nitrosomethylurea.
    Molecular pharmacology, 1975, Volume: 11, Issue:6

    Topics: Alloxan; Animals; Chromatography, Gel; Depression, Chemical; Insulin; Islets of Langerhans; Male; Methylnitrosourea; Mice; Mice, Inbred Strains; Niacinamide; Nitrosourea Compounds; Proinsulin; Proteins; Streptozocin

1975
Islet cell membrane alteration by diabetogenic drugs.
    Laboratory investigation; a journal of technical methods and pathology, 1976, Volume: 34, Issue:5

    Topics: Alloxan; Animals; Cell Membrane; Glucose; In Vitro Techniques; Islets of Langerhans; Niacinamide; Rats; Streptozocin

1976
Inhibition by cyclosporine A of the prooxidant-induced but not of the sodium-induced calcium release from rat kidney mitochondria.
    Biochemical pharmacology, 1991, Nov-06, Volume: 42, Issue:11

    Topics: Adenosine Diphosphate Ribose; Alloxan; Animals; Calcium; Cyclosporine; Female; Glutathione; Glutathione Disulfide; Hydrolysis; Kidney; Mitochondria; Mitochondria, Liver; NAD; Niacinamide; Oxidants; Peroxides; Rats; Rats, Inbred Strains; Sodium; tert-Butylhydroperoxide

1991
Inhibition of pro-oxidant-induced mitochondrial pyridine nucleotide hydrolysis and calcium release by 4-hydroxynonenal.
    The Biochemical journal, 1990, Aug-01, Volume: 269, Issue:3

    Topics: Adenosine Diphosphate Ribose; Aldehydes; Alloxan; Animals; Calcium; Female; Hydrolysis; Intracellular Fluid; Mitochondria, Liver; NAD; Niacinamide; Rats; Rats, Inbred Strains

1990
Pancreatic B cells possess defense mechanisms against cell-specific toxicity.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:14

    Topics: Alloxan; Animals; Antibodies; Cell Survival; Cells, Cultured; Drug Resistance; Glucose; Islets of Langerhans; Niacinamide; Peroxides; Rats; Rats, Inbred Strains; Streptozocin; tert-Butylhydroperoxide

1986
Mechanisms of nicotinamide and thymidine protection from alloxan and streptozocin toxicity.
    Diabetes, 1988, Volume: 37, Issue:8

    Topics: Alloxan; Animals; Cell Line; DNA Damage; DNA, Superhelical; Free Radicals; Hydroxylation; Insulin; Insulin Secretion; Methylnitrosourea; Niacinamide; Rats; Streptozocin; Thymidine

1988
Induction of rat pancreatic B-cell tumors by the combined administration of streptozotocin or alloxan and poly(adenosine diphosphate ribose) synthetase inhibitors.
    Cancer research, 1985, Volume: 45, Issue:4

    Topics: Adenoma, Islet Cell; Alloxan; Amides; Animals; Insulinoma; Male; NAD+ Nucleosidase; Niacinamide; Pancreatic Neoplasms; Picolinic Acids; Poly(ADP-ribose) Polymerase Inhibitors; Proinsulin; Rats; Rats, Inbred Strains; RNA, Messenger; Streptozocin

1985
Mechanism of alloxan-induced calcium release from rat liver mitochondria.
    The Journal of biological chemistry, 1985, Jun-25, Volume: 260, Issue:12

    Topics: Alloxan; Animals; Calcium; Egtazic Acid; Female; Intracellular Membranes; Kinetics; Membrane Potentials; Mitochondria, Liver; NAD; NADP; Niacin; Niacinamide; Oxygen Consumption; Rats; Rats, Inbred Strains; Selenium

1985
[Enzym- and cytotoxic effects of alloxan on the islet system of the pancreas of rats in correlation to the blood-sugar course].
    Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimentelle Chirurgie, 1969, Volume: 150, Issue:1

    Topics: Alloxan; Animals; Blood Glucose; Cell Nucleus; Cytoplasm; Cytoplasmic Granules; Depression, Chemical; Fasting; Glucosephosphate Dehydrogenase; Histocytochemistry; Histological Techniques; Injections, Intraperitoneal; Islets of Langerhans; Male; Niacinamide; Nucleotidases; Pancreas; Rats; Succinate Dehydrogenase

1969
The bioelectrical properties of pancreatic islet cells: effects of diabetogenic agents.
    Diabetologia, 1972, Volume: 8, Issue:3

    Topics: Action Potentials; Alloxan; Animals; Anti-Bacterial Agents; Diabetes Mellitus, Experimental; Female; Glucosamine; Glucose; Glutathione; Glyceraldehyde; Heptoses; In Vitro Techniques; Islets of Langerhans; Leucine; Male; Mice; Niacinamide; Nitroso Compounds; Tolbutamide; Urea

1972
Characteristics of nicotinamide and N1-methylnicotinamide protection from alloxan diabetes in mice.
    Toxicology and applied pharmacology, 1983, Volume: 70, Issue:1

    Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; NAD; Niacinamide

1983
Streptozotocin, but not alloxan, induces DNA repair synthesis in mouse pancreatic islets in vitro.
    Diabetologia, 1983, Volume: 25, Issue:5

    Topics: Alloxan; Animals; DNA Repair; DNA Replication; Islets of Langerhans; Methylurea Compounds; Mice; Mice, Inbred Strains; Niacinamide; Streptozocin; Theophylline

1983
Nicotinamide does not protect islet B-cell metabolism against alloxan toxicity.
    Diabetes, 1984, Volume: 33, Issue:10

    Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Mice; NAD; Niacinamide; Oxidation-Reduction; Oxygen Consumption; Proinsulin

1984
Mechanisms of streptozotocin- and alloxan-induced damage in rat B cells.
    Diabetologia, 1984, Volume: 27, Issue:6

    Topics: Alloxan; Animals; Animals, Newborn; Benzamides; Cells, Cultured; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Methylurea Compounds; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Streptozocin; Superoxide Dismutase

1984
Pancreatic islet cell tumors found in rats given alloxan and nicotinamide.
    Endocrinologia japonica, 1980, Volume: 27, Issue:3

    Topics: Adenoma, Islet Cell; Alloxan; Animals; Glycosuria; Islets of Langerhans; Male; Niacinamide; Pancreatic Neoplasms; Rats

1980
Streptozotocin and alloxan induce DNA strand breaks and poly(ADP-ribose) synthetase in pancreatic islets.
    Nature, 1981, Nov-19, Volume: 294, Issue:5838

    Topics: Alloxan; Amides; Animals; DNA; Islets of Langerhans; Kinetics; NAD; NAD+ Nucleosidase; Niacinamide; Picolinic Acids; Poly(ADP-ribose) Polymerases; Proinsulin; Rats; Streptozocin

1981
Protection by superoxide dismutase, catalase, and poly(ADP-ribose) synthetase inhibitors against alloxan- and streptozotocin-induced islet DNA strand breaks and against the inhibition of proinsulin synthesis.
    The Journal of biological chemistry, 1982, Jun-10, Volume: 257, Issue:11

    Topics: Alloxan; Amides; Animals; Benzamides; Catalase; DNA Replication; Glutathione; In Vitro Techniques; Islets of Langerhans; Male; NAD+ Nucleosidase; Niacinamide; Picolinic Acids; Poly(ADP-ribose) Polymerase Inhibitors; Proinsulin; Rats; Rats, Inbred Strains; Streptozocin; Superoxide Dismutase; Theophylline

1982
Differential insulin secretory activity in rat pancreatic islets and HIT cells.
    Diabetes research (Edinburgh, Scotland), 1994, Volume: 26, Issue:1

    Topics: Alloxan; Animals; Arginine; Cell Line; Cells, Cultured; Cricetinae; Glucose; Insulin; Insulin Antagonists; Insulin Secretion; Islets of Langerhans; Leucine; Male; Niacinamide; Rats; Rats, Wistar; Species Specificity; Streptozocin

1994
Pretreatment of fetal porcine pancreas in culture with nicotinamide accelerates reversal of diabetes after transplantation to nude mice.
    Surgery, 1993, Volume: 113, Issue:2

    Topics: Alloxan; Animals; Blood Glucose; Cell Differentiation; Cells, Cultured; Diabetes Mellitus, Experimental; DNA; Glucose; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Mice; Mice, Nude; Niacinamide; Oxidation-Reduction; Swine; Theophylline

1993
Activation of a novel non-selective cation channel by alloxan and H2O2 in the rat insulin-secreting cell line CRI-G1.
    The Journal of physiology, 1997, May-15, Volume: 501 ( Pt 1)

    Topics: Alloxan; Animals; Cell Polarity; Cysteine; Free Radical Scavengers; Hydrogen Peroxide; Insulinoma; Islets of Langerhans; Membrane Potentials; Niacinamide; Patch-Clamp Techniques; Rats; Reactive Oxygen Species; Thiourea; Tumor Cells, Cultured

1997
Sensitivity of HaCat keratinocytes to diabetogenic toxins.
    Biochemical pharmacology, 2002, Jan-15, Volume: 63, Issue:2

    Topics: Alloxan; Analysis of Variance; Apoptosis; Benzamides; Cell Line; Cell Survival; Enzyme Inhibitors; Guanosine; Humans; Keratinocytes; Necrosis; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Streptozocin

2002
[Effect of nicotinic acid amide on metabolism of alloxan diabetic rat liver in vitro. I. Oxygen consumption in liver cultured in medium containing sodium aceto-acetate and nicotinic acid amide].
    Tip Fakultesi mecmuasi, 1957, Volume: 20, Issue:4

    Topics: Alloxan; Amides; Diabetes Mellitus; In Vitro Techniques; Liver; Niacin; Niacinamide; Nicotinic Acids; Oxygen Consumption; Sodium; Sodium Acetate

1957
[Effects of nicotinamide on ketone metabolism by liver of alloxan diabetic rats in vitro. II. Study of acetoacetate utilization by distillation method].
    Tip Fakultesi mecmuasi, 1958, Volume: 21, Issue:3

    Topics: Acetoacetates; Alloxan; Animals; Diabetes Mellitus, Experimental; Distillation; In Vitro Techniques; Liver; Niacin; Niacinamide; Nicotinic Acids; Rats

1958
ACQUIRED CHROMOSOMAL ANOMALIES INDUCED IN MICE BY KNOWN TERATOGEN.
    JAMA, 1964, Mar-14, Volume: 187

    Topics: Alloxan; Animals; Chromosome Aberrations; Cleft Palate; Embryo, Mammalian; Embryo, Nonmammalian; Female; Fetal Diseases; Hydrocortisone; Hypoxia; Mice; Niacin; Niacinamide; Pregnancy; Pregnancy, Animal; Research; Teratogens; Toxicology

1964
Differentiation of mesenchymal stem cells to insulin-producing cells and their impact on type 1 diabetic rats.
    Journal of physiology and biochemistry, 2010, Volume: 66, Issue:2

    Topics: Alloxan; Animals; Cell Differentiation; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Glucose; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Mercaptoethanol; Mesenchymal Stem Cells; Niacinamide; Rats; Rats, Wistar

2010
Experimentally induced rodent models of type 2 diabetes.
    Methods in molecular biology (Clifton, N.J.), 2012, Volume: 933

    Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Fetal Growth Retardation; Fructose; Mice; Niacinamide; Pancreas; Pancreatectomy; Rats; Sodium Glutamate; Streptozocin

2012
Coadministration of alloxan and nicotinamide in rats produces biochemical changes in blood and pathological alterations comparable to the changes in type II diabetes mellitus.
    Human & experimental toxicology, 2016, Volume: 35, Issue:8

    Topics: Adiponectin; Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Synergism; Insulin; Kidney; Liver; Male; Niacinamide; Pancreas; Rats, Sprague-Dawley

2016
Therapeutic effect of vitamin B
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 105

    Topics: Alloxan; Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Supplements; DNA Damage; Hyperglycemia; Liver; Male; Niacinamide; Oxidative Stress; Rats; Rats, Wistar

2018