niacinamide has been researched along with allopurinol in 47 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (51.06) | 18.7374 |
| 1990's | 8 (17.02) | 18.2507 |
| 2000's | 6 (12.77) | 29.6817 |
| 2010's | 7 (14.89) | 24.3611 |
| 2020's | 2 (4.26) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Curzon, G; Fernando, JC; Joseph, MH | 1 |
| Badawy, AA; Evans, M | 2 |
| Huh, K; Iwata, H; Yamamoto, I | 1 |
| Di Stefano, A; Marinello, E; Pizzichini, M | 1 |
| Andreoli, SP | 1 |
| Banks, RB; Cooke, RT | 1 |
| Chaykin, S; Murray, KN; Watson, JG | 1 |
| Chaykin, S; McDaniel, D; Murashige, K | 1 |
| Hori, M; Komai, T; Kunimoto, T; Tsukada, I | 1 |
| Arneson, RM | 1 |
| Chaykin, S; Sparthan, M | 1 |
| Curzon, G; Green, AR | 1 |
| Chaykin, S; Stanulović, M | 1 |
| Fox, IH; Kelley, WN | 1 |
| Chaykin, S; Chu, AE | 1 |
| Chaykin, S; Murray, KN | 1 |
| Fuji, M; Fukumoto, Y; Nagamatsu, A; Shimeno, H | 1 |
| Baue, AE; Chaudry, IH | 1 |
| Bunting, JW; Laderoute, KR; Norris, DJ | 1 |
| Aronson, JK; Curzon, G; Green, AR; Woods, HF | 1 |
| Annable, L; Chouinard, G; Young, SN | 1 |
| Wang, M; Wu, X | 1 |
| Burkart, V; Bürkle, A; Fengler, E; Heller, B; Jalowy, A; Kolb, H; Müller, M; Radons, J | 1 |
| Gu, K; Kin, S; Nakayama, K; Nosaka, S; Saitoh, Y; Sasaki, T; Yamauchi, M | 2 |
| Bahn, RS; Barnes, S; Burch, HB; Lahiri, S | 1 |
| Demiryürek, AT; Kane, KA; Kennedy, S; Wadsworth, RM; Wainwright, CL | 1 |
| Burkart, V; Bürkle, A; Fengler, E; Heller, B; Kolb, H; Müller, M; Radons, J | 1 |
| Endo, T; Iwamura, M; Koshiba, K; Kumano, K; Masaki, Y; Okubo, M; Yokota, K | 1 |
| Bouzas, EA; Karadimas, P; Koutras, DA; Mastorakos, G | 1 |
| Decker, RW; Malejka-Giganti, D; Ritter, CL | 1 |
| Castro, GD; Castro, JA; Costantini, MH; Delgado de Layño, AM | 1 |
| GREENLEE, L; HANDLER, P | 2 |
| Li, PL; Teggatz, EG; Yi, F; Zhang, AY; Zou, AP | 1 |
| Iwanaga, Y; Kobayashi, N; Matsumoto, S; Nagata, H; Nakai, Y; Nakamura, T; Noguchi, H; Okitsu, T; Ueda, M; Wada, H; Yonekawa, Y | 1 |
| Alejandro, R; Alvarez, A; Fraker, C; Goss, JA; Ichii, H; Inverardi, L; Khan, A; Kuroda, Y; Messinger, S; Ricordi, C; Wang, X | 1 |
| Kitamura, S; Miyake, K; Morita, S; Ohta, S; Sanoh, S; Sugihara, K; Tayama, Y | 1 |
| Chujo, D; Fujita, Y; Kobayashi, N; Lamont, J; Levy, MF; Matsumoto, S; Naziruddin, B; Noguchi, H; Onaca, N; Shimoda, M; Takita, M; Tate, C | 1 |
| Brown, MB; Feldman, EL; Mehta, M; Plunkett, CD; Pop-Busui, R; Raffel, DM; Stevens, MJ; White, EA | 1 |
| Li, SY; Meng, FH; Sun, Q; Wang, L; Wu, QX; Zhang, TJ; Zhang, Y | 1 |
| Meng, FH; Tu, S; Wu, YH; Zhang, TJ; Zhang, Y; Zhang, ZH | 1 |
| Agunbiade, TB; Ajadi, IO; Ajadi, MB; Akinnagbe, NT; Amusa, OA; Michael, OS; Olaniyi, KS | 1 |
| Meng, FH; Tu, S; Zhang, TJ; Zhang, X; Zhang, Y; Zhang, ZH | 1 |
3 trial(s) available for niacinamide and allopurinol
| Article | Year |
|---|---|
Metabolism of an oral tryptophan load. II: Effect of pretreatment with the putative tryptophan pyrrolase inhibitors nicotinamide or allopurinol.
Topics: Administration, Oral; Adult; Allopurinol; Humans; Male; Niacinamide; Tryptophan; Tryptophan Oxygenase | 1980 |
Antioxidant agents in the treatment of Graves' ophthalmopathy.
Topics: Administration, Oral; Adult; Allopurinol; Antioxidants; Drug Evaluation; Female; Graves Disease; Humans; Intraocular Pressure; Male; Middle Aged; Niacinamide; Patient Satisfaction; Pilot Projects; Prospective Studies; Treatment Outcome; Visual Acuity | 2000 |
Effects of triple antioxidant therapy on measures of cardiovascular autonomic neuropathy and on myocardial blood flow in type 1 diabetes: a randomised controlled trial.
Topics: Adolescent; Adult; Aged; Allopurinol; Antioxidants; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Female; Humans; Male; Middle Aged; Myocardium; Niacinamide; Regional Blood Flow; Young Adult | 2013 |
44 other study(ies) available for niacinamide and allopurinol
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Letter: Tryptophan plus a pyrrolase inhibitor for depression?
Topics: Allopurinol; Brain; Depression; Drug Synergism; Drug Therapy, Combination; Humans; Niacinamide; Time Factors; Tryptophan | 1975 |
Letter: Tryptophan plus a pyrrolase inhibitor for depression.
Topics: Allopurinol; Animals; Depression; Drug Synergism; Drug Therapy, Combination; Glucose; Humans; Niacinamide; Rats; Rats, Inbred Strains; Tryptophan; Tryptophan Oxygenase | 1975 |
[Hepatic allopurinol oxidizing enzyme in mice].
Topics: Aldehyde Oxidoreductases; Allopurinol; Animals; Chlorpromazine; Desipramine; Dexamethasone; Dialysis; Diphenhydramine; Hot Temperature; Imipramine; Ions; Liver; Male; Mice; Niacinamide; Oxypurinol; Testosterone; Time Factors; Vitamin K; Xanthine Oxidase | 1975 |
Nicotinamide and liver xanthine oxidase.
Topics: Animals; Enzyme Activation; Kinetics; Liver; Male; Niacinamide; Nicotinic Acids; Rats; Xanthine Oxidase | 1979 |
Mechanisms of endothelial cell ATP depletion after oxidant injury.
Topics: Adenosine Triphosphate; Benzamides; Cells, Cultured; DNA Damage; Endothelium, Vascular; Enzyme Activation; Glucose Oxidase; Humans; NAD; Niacinamide; Oxidation-Reduction; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Umbilical Veins; Xanthine Oxidase | 1989 |
Chromate reduction by rabbit liver aldehyde oxidase.
Topics: Aldehyde Oxidase; Aldehyde Oxidoreductases; Allopurinol; Animals; Chromates; Cytosol; In Vitro Techniques; Kinetics; Liver; Niacinamide; Oxidation-Reduction; Potassium Cyanide; Rabbits; Vitamin K | 1986 |
Letter: Tryptophan plus a pyrrolase inhibitor for depression?
Topics: Adult; Allopurinol; Animals; Depression; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Humans; In Vitro Techniques; Niacinamide; Rats; Tryptophan; Tryptophan Oxygenase | 1974 |
Catalysis of the direct transfer of oxygen from nicotinamide N-oxide to xanthine by xanthine oxidase.
Topics: Animals; Catalysis; Liver; Milk; Niacinamide; Oxides; Oxygen; Oxygen Isotopes; Uric Acid; Xanthine Oxidase | 1966 |
N-methylnicotinamide oxidation in hog liver.
Topics: Animals; Chromatography, Paper; Cyanides; Hot Temperature; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Niacinamide; Pyridones; Swine; Xanthine Oxidase | 1966 |
Isolation and properties of the enzyme which catalyzes of oxidation of formycin B.
Topics: Allopurinol; Animals; Anti-Bacterial Agents; Hypoxanthines; Liver; Niacinamide; Nucleosides; Oxidation-Reduction; Oxidoreductases; Rabbits; Ultracentrifugation | 1969 |
Substrate-induced chemiluminescence of xanthine oxidase and aldehyde oxidase.
Topics: Aldehydes; Animals; Catalase; Cattle; Chemical Phenomena; Chemistry; Cysteine; Erythrocytes; Free Radicals; Hydrogen Peroxide; Kinetics; Liver; Luminescent Measurements; Milk; Niacinamide; Nucleotides; Oxidoreductases; Oxygen; Rabbits; Sulfites; Xanthine Oxidase | 1970 |
Determination of ncotinamide N-oxide--a human excretory product.
Topics: Adult; Animals; Cricetinae; Cyanides; Diet; Female; Humans; Kinetics; Male; Methods; Mice; Niacinamide; Oxides; Radioisotope Dilution Technique; Rats; Species Specificity; Xanthine Oxidase | 1969 |
The effect of tryptophan metabolites on brain 5-hydroxytryptamine metabolism.
Topics: Alanine; Allopurinol; Amino Acids; Animals; Brain; Brain Chemistry; Carbon Isotopes; Carboxy-Lyases; Histamine; Kynurenic Acid; Kynurenine; Male; Methanol; Methyldopa; Mixed Function Oxygenases; Niacinamide; Nicotinic Acids; Nitroglycerin; ortho-Aminobenzoates; Phenylalanine; Phenylbutyrates; Picolinic Acids; Pyridines; Pyridoxal Phosphate; Pyridoxine; Rats; Serotonin; Sulfuric Acids; Time Factors; Tryptophan; Tryptophan Oxygenase; Xanthurenates | 1970 |
Metabolic origins of the pyridones of N 1 -methylnicotinamide in man and rat.
Topics: Aldehydes; Allopurinol; Animals; Carbon Isotopes; Catalysis; Chromatography, Paper; Enzyme Activation; Genotype; Humans; Hydrogen-Ion Concentration; Kinetics; Liver; Niacinamide; Oxidoreductases; Picolines; Pyridones; Rats; Species Specificity; Xanthine Oxidase | 1971 |
Pharmacological alterations of intracellular phosphoribosylpyrophosphate (PP-ribose-P) in human tissues.
Topics: Adenine; Allopurinol; Deoxy Sugars; Erythrocytes; Fibroblasts; Glucose; Guanine Nucleotides; Humans; Inosine Nucleotides; Methylene Blue; Niacinamide; Nicotinic Acids; Orotic Acid; Pentosephosphates; Pentosyltransferases; Purines; Skin; Time Factors | 1973 |
Structural requirement of ligands for affinity chromatography absorbents: purification of aldehyde and xanthine oxidases.
Topics: Adsorption; Aldehyde Oxidoreductases; Animals; Benzyl Compounds; Binding Sites; Binding, Competitive; Chromatography, Affinity; Evaluation Studies as Topic; Hydrogen-Ion Concentration; Kinetics; Ligands; Liver; Methods; Molecular Conformation; Niacinamide; Protein Binding; Structure-Activity Relationship; Xanthine Oxidase | 1974 |
The reduction of nicotinamide N-oxide by xanthine oxidase.
Topics: Animals; Cyanides; Hot Temperature; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Mercaptoethanol; Milk; NAD; Niacinamide; Oxides; Spectrophotometry; Swine; Xanthine Oxidase | 1966 |
Effect of combined administration of tryptophan with putative tryptophan pyrrolase inhibitors, DL-3-pyridylalanine, allopurinol or nicotinamide, on brain serotonin concentration.
Topics: Alanine; Allopurinol; Animals; Brain Chemistry; Liver; Male; Niacinamide; Rats; Rats, Inbred Strains; Serotonin; Tryptophan; Tryptophan Oxygenase | 1984 |
The use of substrates and energy in the treatment of shock.
Topics: Adenosine; Adenosine Triphosphate; Allopurinol; Animals; Cyclic AMP; Dogs; Glucose; Humans; Inosine; Insulin; Niacinamide; Rabbits; Rats; Shock | 1980 |
The pH dependence of xanthine oxidase catalysis in basic solution.
Topics: Deuterium; Hydrogen-Ion Concentration; Kinetics; Niacinamide; Nicotinic Acids; Pyridinium Compounds; Quinolinium Compounds; Xanthine Oxidase | 1980 |
Tryptophan in the treatment of depression.
Topics: Allopurinol; Antidepressive Agents, Tricyclic; Ascorbic Acid; Bipolar Disorder; Depression; Electroconvulsive Therapy; Humans; Monoamine Oxidase Inhibitors; Niacinamide; Pyridoxine; Tryptophan | 1981 |
Dietary nicotinamide supplementation increases xanthine oxidoreductase activity in the kidney and heart but not liver of obese Zucker rats.
Topics: Animals; Female; Food, Fortified; Heart; Kidney; Liver; Myocardium; Niacinamide; Obesity; Organ Size; Rats; Rats, Mutant Strains; Rats, Zucker; Xanthine Dehydrogenase; Xanthine Oxidase | 1995 |
Analysis of oxygen radical toxicity in pancreatic islets at the single cell level.
Topics: Animals; Cell Death; Cell Survival; Cells, Cultured; DNA Damage; Fluorescent Antibody Technique; Hypoxanthine; Hypoxanthines; Islets of Langerhans; Kinetics; NAD; Niacinamide; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Reactive Oxygen Species; Xanthine Oxidase | 1994 |
The HTK solution with nicorandil can improve cardiac function after simple cold storage.
Topics: Adenosine; Allopurinol; Animals; Biomarkers; Blood Pressure; Cardiac Output; Cardioplegic Solutions; Cold Temperature; Coronary Circulation; Glucose; Glutathione; Heart; Heart Rate; Hemodynamics; Insulin; Male; Mannitol; Niacinamide; Nicorandil; Organ Preservation; Organ Preservation Solutions; Potassium Chloride; Procaine; Raffinose; Rats; Rats, Wistar; Troponin; Troponin T; Vasodilator Agents | 1996 |
Cardioprotective effect of nicorandil in histidine-tryptophan-ketoglurate solution during the cold storage of isolated hearts.
Topics: Adenosine; Allopurinol; Animals; Cardioplegic Solutions; Cold Temperature; Cyclic GMP; Glucose; Glutathione; Heart; Insulin; Male; Mannitol; Niacinamide; Nicorandil; Organ Preservation; Organ Preservation Solutions; Potassium Chloride; Procaine; Raffinose; Rats; Rats, Wistar; Vasodilator Agents | 1996 |
Superoxide radical production stimulates retroocular fibroblast proliferation in Graves' ophthalmopathy.
Topics: Allopurinol; Analysis of Variance; Antioxidants; Antithyroid Agents; Cell Division; Connective Tissue; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Graves Disease; Humans; Methimazole; Niacinamide; Reactive Oxygen Species; Smoking; Superoxides; Xanthine Oxidase | 1997 |
Influence of nitric oxide on luminol-enhanced chemiluminescence measured from porcine-stimulated leukocytes.
Topics: Animals; Arginine; Cell-Free System; Indicators and Reagents; Leukocytes; Luminescent Measurements; Luminol; NG-Nitroarginine Methyl Ester; Niacinamide; Nicorandil; Nitric Oxide; Swine; Sydnones; Tetradecanoylphorbol Acetate; Vasodilator Agents; Xanthine; Xanthine Oxidase; Xanthines | 1997 |
DNA-damage and NAD(+)-depletion are initial events in oxygen radical induced islet cell death.
Topics: Animals; Cell Death; Cell Survival; Cells, Cultured; DNA Damage; Hypoxanthine; Islets of Langerhans; NAD; Niacinamide; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Reactive Oxygen Species; Xanthine Oxidase | 1997 |
Protective effect of nicaraven against prolonged cold kidney preservation and reperfusion injury.
Topics: Adenosine; Allopurinol; Animals; Antioxidants; Cold Temperature; Creatinine; Diuresis; Dogs; Glutathione; Hypertonic Solutions; In Vitro Techniques; Insulin; Kidney; Kidney Transplantation; Male; Niacinamide; Organ Preservation; Organ Preservation Solutions; Raffinose; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Transplantation, Autologous | 1998 |
Reductions of nitro and 9-Oxo groups of environmental nitrofluorenes by the rat mammary gland in vitro.
Topics: Air Pollutants; Allopurinol; Animals; Breast; Cytosol; Dicumarol; Female; Fluorenes; Hypoxanthine; Indomethacin; Microsomes; Niacinamide; Oxidation-Reduction; Oxygen; Pyrazoles; Pyrimidines; Rats; Rats, Sprague-Dawley; Rutin; Vitamin K; Xanthine | 2000 |
Rat ventral prostate xanthine oxidase bioactivation of ethanol to acetaldehyde and 1-hydroxyethyl free radicals: analysis of its potential role in heavy alcohol drinking tumor-promoting effects.
Topics: Acetaldehyde; Alcohol Drinking; Allopurinol; Animals; Antimetabolites; Caffeine; Carcinogens; Chromatography, Gas; Cytosol; Diet; Enzyme Inhibitors; Ethanol; Free Radicals; Gas Chromatography-Mass Spectrometry; Hypoxanthine; Male; Meat; NAD; Neoplasms; Niacinamide; Phosphodiesterase Inhibitors; Prostate; Prostatic Neoplasms; Purines; Rats; Rats, Sprague-Dawley; Spin Trapping; Temperature; Theobromine; Theophylline; Time Factors; Vasodilator Agents; Xanthine; Xanthine Oxidase | 2001 |
XANTHINE OXIDASE. VI. INFLUENCE OF PH ON SUBSTRATE SPECIFICITY.
Topics: Acetaldehyde; Aldehydes; Hydrogen-Ion Concentration; Hypoxanthines; Milk; Niacin; Niacinamide; Nicotinic Acids; Oxidoreductases; Purines; Pyridines; Quinolines; Research; Spectrophotometry; Substrate Specificity; Xanthine Oxidase; Xanthines | 1964 |
XANTHINE OXIDASE. VII. INHIBITION BY AMINO GROUP REAGENTS.
Topics: Aldehydes; Carbon Isotopes; Chromatography; Dialysis; Enzyme Inhibitors; Flavin-Adenine Dinucleotide; Humans; Indicators and Reagents; Milk; Niacin; Niacinamide; Nitrobenzenes; Oxidoreductases; Renal Dialysis; Research; Spectrum Analysis; Sulfonic Acids; Xanthine Oxidase | 1964 |
Enhanced production and action of cyclic ADP-ribose during oxidative stress in small bovine coronary arterial smooth muscle.
Topics: ADP-ribosyl Cyclase; Animals; Calcium Signaling; Cattle; Cells, Cultured; Chromatography, High Pressure Liquid; Coronary Vessels; Cyclic ADP-Ribose; Hydrogen Peroxide; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Niacinamide; Oxidative Stress; Ryanodine; Second Messenger Systems; Superoxides; Tetracaine; Vasoconstriction; Xanthine Oxidase | 2004 |
Modified two-layer preservation method (M-Kyoto/PFC) improves islet yields in islet isolation.
Topics: Adenosine; Adenosine Triphosphate; Allopurinol; Animals; Collagenases; Epoprostenol; Fluorocarbons; Glutamine; Glutathione; Hydroxyethyl Starch Derivatives; In Vitro Techniques; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Magnesium Sulfate; Mice; Mice, SCID; Niacinamide; Organ Preservation; Organ Preservation Solutions; Raffinose; Swine; Trehalose; Trypsin | 2006 |
Improved human islet isolation using nicotinamide.
Topics: Adenosine; Adult; Allopurinol; Cell Separation; Diabetes Mellitus, Type 1; Glutathione; Humans; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Middle Aged; Niacinamide; Organ Preservation; Organ Preservation Solutions; Pancreas; Raffinose; Retrospective Studies | 2006 |
Effect of tea beverages on aldehyde oxidase activity.
Topics: Aldehyde Oxidase; Animals; Beverages; Catechin; Cytosol; Herb-Drug Interactions; Humans; Liver; Male; Niacinamide; Rats; Tea; Xanthine Oxidase | 2011 |
Improved pancreatic islet isolation outcome in autologous transplantation for chronic pancreatitis.
Topics: Adenosine; Adult; Allopurinol; Body Weight; C-Peptide; Epoprostenol; Female; Fluorocarbons; Follow-Up Studies; Glutamine; Glutathione; Humans; Hydroxyethyl Starch Derivatives; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Magnesium Sulfate; Male; Middle Aged; Niacinamide; Organ Preservation; Organ Preservation Solutions; Pancreatitis, Chronic; Raffinose; Transplantation, Autologous; Trehalose | 2012 |
Design, synthesis and biological evaluation of N-(4-alkoxy-3-cyanophenyl)isonicotinamide/nicotinamide derivatives as novel xanthine oxidase inhibitors.
Topics: Animals; Cattle; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Models, Molecular; Molecular Structure; Niacinamide; Structure-Activity Relationship; Xanthine Oxidase | 2017 |
Design, synthesis and biological evaluation of N-(3-(1H-tetrazol-1-yl)phenyl)isonicotinamide derivatives as novel xanthine oxidase inhibitors.
Topics: Animals; Benzamides; Cattle; Drug Design; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Niacinamide; Nitriles; Protein Binding; Pyridines; Structure-Activity Relationship; Tetrazoles; Uric Acid; Xanthine Oxidase | 2019 |
Acetate ameliorates nephrotoxicity in streptozotocin-nicotinamide-induced diabetic rats: Involvement of xanthine oxidase activity.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Atherosclerosis; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Fasting; Glutathione; Inflammation Mediators; Insulin; Kidney; Lipid Peroxidation; Male; Models, Biological; Niacinamide; Nitric Oxide; Rats, Wistar; Sodium Acetate; Streptozocin; Triglycerides; Xanthine Oxidase | 2021 |
N-(3-cyano-1H-indol-5-yl)isonicotinamide and N-(3-cyano-1H-indol-5-yl)-1H-benzo[d]imidazole-5-carboxamide derivatives: Novel amide-based xanthine oxidase inhibitors.
Topics: Amides; Animals; Drug Design; Enzyme Inhibitors; Female; Hyperuricemia; Imidazoles; Male; Molecular Docking Simulation; Niacinamide; Rats, Sprague-Dawley; Structure-Activity Relationship; Xanthine Oxidase | 2021 |