niacin and mk 6892

niacin has been researched along with mk 6892 in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Cai, TQ; Carballo-Jane, E; Chen, Q; Cheng, K; Colletti, SL; Deng, Q; Ding, FX; Forrest, MJ; Hammond, ML; Holt, TG; Krsmanovic, ML; Luell, S; Raghavan, S; Ren, N; Shen, HC; Taggart, AK; Tata, JR; Tong, X; Wang, J; Waters, MG; Wilsie, LC; Wolff, MS; Wu, KK; Wu, TJ1
Cho, H; Jadhav, VB; Jeong, DY; Kim, HY; Lee, S; Park, WK; Song, JH1
Cheng, X; Duan, J; Duan, X; He, X; Li, J; Li, X; Shen, S; Wang, D; Xu, HE; Yuan, Q; Zhu, S1

Other Studies

3 other study(ies) available for niacin and mk 6892

ArticleYear
Discovery of a biaryl cyclohexene carboxylic acid (MK-6892): a potent and selective high affinity niacin receptor full agonist with reduced flushing profiles in animals as a preclinical candidate.
    Journal of medicinal chemistry, 2010, Mar-25, Volume: 53, Issue:6

    Topics: Animals; Area Under Curve; Binding, Competitive; Carboxylic Acids; CHO Cells; Cricetinae; Cricetulus; Cyclohexanecarboxylic Acids; Cyclohexenes; Dogs; Drug Discovery; Drug Evaluation, Preclinical; Fatty Acids, Nonesterified; Humans; Metabolic Clearance Rate; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Chemical; Molecular Structure; Oxadiazoles; Rats; Receptors, G-Protein-Coupled; Receptors, Nicotinic; Structure-Activity Relationship; Vasodilation

2010
Discovery of 4-(phenyl)thio-1H-pyrazole derivatives as agonists of GPR109A, a high affinity niacin receptor.
    Archives of pharmacal research, 2015, Volume: 38, Issue:6

    Topics: Animals; Arrestins; beta-Arrestins; beta-Lactamases; Calcium Signaling; CHO Cells; Cricetinae; Cricetulus; Cyclohexanecarboxylic Acids; High-Throughput Screening Assays; Humans; Indicators and Reagents; Niacin; Nicotinic Agonists; Oxadiazoles; Pyrazoles; Receptors, G-Protein-Coupled; Receptors, Nicotinic; Structure-Activity Relationship

2015
Molecular recognition of niacin and lipid-lowering drugs by the human hydroxycarboxylic acid receptor 2.
    Cell reports, 2023, Nov-28, Volume: 42, Issue:11

    Topics: Cryoelectron Microscopy; Cyclohexanecarboxylic Acids; Humans; Ligands; Lipids; Niacin; Receptors, G-Protein-Coupled

2023
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