niacin and mk 0354

niacin has been researched along with mk 0354 in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Behan, DP; Boatman, PD; Cai, TQ; Carballo-Jane, E; Chen, R; Cheng, K; Cherrier, MC; Colletti, SL; Connolly, DT; Gharbaoui, T; Jung, JK; Richman, JG; Sage, CR; Schrader, TO; Semple, G; Shin, YJ; Skinner, PJ; Taggart, AK; Tamura, SY; Tata, JR; Waters, MG; Webb, PJ1
Carballo-Jane, E; Chang, S; Cheng, K; Colletti, SL; Esser, C; Gerard Waters, M; Imbriglio, JE; Jung, JK; Liang, R; Raghavan, S; Schmidt, D; Schrader, TO; Smenton, A; Taggart, AK; Tata, JR; Tria, S1
Boatman, PD; Carballo-Jane, E; Chen, R; Cherrier, MC; Johnson, BR; Jung, JK; Kasem, M; Knudsen, J; Richman, JG; Sage, CR; Schrader, TO; Semple, G; Skinner, PJ; Taggart, AK; Webb, PJ; Xu, J1
Carballo-Jane, E; Chang, S; Cheng, K; Colletti, SL; Esser, C; Holt, TG; Imbriglio, JE; Jung, JK; Liang, R; Raghavan, S; Schmidt, D; Schrader, TO; Smenton, A; Taggart, AK; Tata, JR; Tria, S; Waters, MG; Wolff, MS1
Boatman, PD; Carballo-Jane, E; Caro, L; Chen, R; Cherrier, MC; Colletti, SL; Connolly, DT; Cote, J; Hammond, M; Johnson, BR; Jung, JK; Kasem, M; Knudsen, J; Lai, E; Lauring, B; Luo, WL; Richman, JG; Sage, CR; Schrader, TO; Semple, G; Skinner, P; Taggart, AK; Tata, JR; Wagner, J; Waters, MG; Webb, PJ; Xu, J1

Trials

1 trial(s) available for niacin and mk 0354

ArticleYear
(1aR,5aR)1a,3,5,5a-Tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalene-4-carboxylic acid (MK-1903): a potent GPR109a agonist that lowers free fatty acids in humans.
    Journal of medicinal chemistry, 2012, Apr-26, Volume: 55, Issue:8

    Topics: Animals; Fatty Acids, Nonesterified; Humans; Hypolipidemic Agents; Male; Niacin; Pyrazoles; Rats; Receptors, G-Protein-Coupled; Receptors, Nicotinic; Stereoisomerism; Vasodilator Agents

2012

Other Studies

4 other study(ies) available for niacin and mk 0354

ArticleYear
3-(1H-tetrazol-5-yl)-1,4,5,6-tetrahydro-cyclopentapyrazole (MK-0354): a partial agonist of the nicotinic acid receptor, G-protein coupled receptor 109a, with antilipolytic but no vasodilatory activity in mice.
    Journal of medicinal chemistry, 2008, Aug-28, Volume: 51, Issue:16

    Topics: Adipocytes; Animals; Fatty Acids, Nonesterified; Humans; Hypolipidemic Agents; Lipolysis; Male; Mice; Mice, Inbred C57BL; Pyrazoles; Receptors, G-Protein-Coupled; Receptors, Nicotinic; Tetrazoles; Vasodilation

2008
GPR109a agonists. Part 1: 5-Alkyl and 5-aryl-pyrazole-tetrazoles as agonists of the human orphan G-protein coupled receptor GPR109a.
    Bioorganic & medicinal chemistry letters, 2009, Apr-15, Volume: 19, Issue:8

    Topics: Animals; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotinic Agonists; Pyrazoles; Receptors, G-Protein-Coupled; Receptors, Nicotinic; Tetrazoles; Vasodilation

2009
Potent tricyclic pyrazole tetrazole agonists of the nicotinic acid receptor (GPR109a).
    Bioorganic & medicinal chemistry letters, 2010, May-01, Volume: 20, Issue:9

    Topics: Animals; Dogs; Haplorhini; Humans; Mice; Pyrazoles; Rats; Receptors, G-Protein-Coupled; Receptors, Nicotinic; Tetrazoles; Vasodilator Agents

2010
GPR109a agonists. Part 2: pyrazole-acids as agonists of the human orphan G-protein coupled receptor GPR109a.
    Bioorganic & medicinal chemistry letters, 2010, Aug-01, Volume: 20, Issue:15

    Topics: Animals; Fatty Acids; Humans; Mice; Niacin; Pyrazoles; Receptors, G-Protein-Coupled; Receptors, Nicotinic

2010
chemdatabank.com