Compounds > nevirapine

nevirapine and uc-781

nevirapine has been researched along with uc-781 in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's8 (66.67)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jorgensen, WL; Rizzo, RC; Tirado-Rives, J; Wang, DP1
Jorgensen, WL; Kroeger Smith, MB; Rizzo, RC; Smith, RH; Tirado-Rives, J; Udier-Blagović, M; Wang, DP; Watkins, EK1
Kang, X; Kollman, PA; Kuntz, ID; Wang, J1
Anderson, KS; Basavapathruni, A; Hamilton, AD; Jorgensen, WL; Ruiz-Caro, J; Tirado-Rives, J1
Anderson, KS; Bailey, CM; Basavapathruni, A; Hamilton, AD; Jorgensen, WL; Kim, JT; Ruiz-Caro, J; Wang, L1
Anderson, KS; Bailey, CM; Barreiro, G; Domaoal, RA; Guimarães, CR; Jorgensen, WL; Kim, JT; Wang, L1
Anderson, KS; Bollini, M; Cisneros, JA; Jorgensen, WL; Spasov, KA1
Ariën, KK; Augustyns, K; Cos, P; Dirié, B; Heeres, J; Joossens, J; Lewi, PJ; Lyssens, S; Maes, L; Michiels, J; Van der Veken, P; Vanham, G; Venkatraj, M1
Barnard, J; Borkow, G; Parniak, MA1
Balzarini, J; Camarasa, MJ; Dmitrienko, GI; Parniak, MA; Sluis-Cremer, N1
Balzarini, J; Burt, V; Carbonez, A; De Clercq, E; Kleim, JP1
Ariën, KK; Heyndrickx, L; Michiels, J; Quiñones-Mateu, ME; Selhorst, P; Terrazas-Aranda, K; Vanham, G; Vazquez, AC; Vereecken, K; Weber, J1

Other Studies

12 other study(ies) available for nevirapine and uc-781

ArticleYear
Antiviral drug design: computational analyses of the effects of the L100I mutation for HIV-RT on the binding of NNRTIs.
    Bioorganic & medicinal chemistry letters, 2001, Nov-05, Volume: 11, Issue:21

    Topics: Drug Design; HIV Reverse Transcriptase; Models, Molecular; Mutation; Reverse Transcriptase Inhibitors

2001
Prediction of activity for nonnucleoside inhibitors with HIV-1 reverse transcriptase based on Monte Carlo simulations.
    Journal of medicinal chemistry, 2002, Jul-04, Volume: 45, Issue:14

    Topics: Alkynes; Anilides; Benzoxazines; Computer Simulation; Cyclopropanes; HIV Reverse Transcriptase; Hydrogen Bonding; Models, Molecular; Monte Carlo Method; Nevirapine; Oxazines; Protein Binding; Quinoxalines; Regression Analysis; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Uracil

2002
Hierarchical database screenings for HIV-1 reverse transcriptase using a pharmacophore model, rigid docking, solvation docking, and MM-PB/SA.
    Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7

    Topics: Allosteric Site; Anti-HIV Agents; Crystallography, X-Ray; Databases, Factual; Drug Design; HIV Reverse Transcriptase; Models, Molecular; Molecular Conformation; Molecular Structure; Protein Binding; Quantitative Structure-Activity Relationship; Reverse Transcriptase Inhibitors; Statistics as Topic; Thermodynamics

2005
Computer-aided design of non-nucleoside inhibitors of HIV-1 reverse transcriptase.
    Bioorganic & medicinal chemistry letters, 2006, Volume: 16, Issue:3

    Topics: Computer-Aided Design; Drug Resistance, Multiple, Viral; HIV Infections; HIV Reverse Transcriptase; Models, Molecular; Molecular Structure; Monte Carlo Method; Mutation; Reverse Transcriptase Inhibitors

2006
Optimization of diarylamines as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
    Bioorganic & medicinal chemistry letters, 2006, Volume: 16, Issue:3

    Topics: Amines; Drug Resistance, Multiple, Viral; Heterocyclic Compounds; HIV Infections; HIV Reverse Transcriptase; Hydrophobic and Hydrophilic Interactions; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thiazoles

2006
From docking false-positive to active anti-HIV agent.
    Journal of medicinal chemistry, 2007, Nov-01, Volume: 50, Issue:22

    Topics: Anti-HIV Agents; Cell Line; Databases, Factual; HIV Reverse Transcriptase; HIV-1; Humans; Ligands; Models, Molecular; Molecular Conformation; Oxadiazoles; Quantitative Structure-Activity Relationship; Reverse Transcriptase Inhibitors; Thermodynamics

2007
Optimization of diarylazines as anti-HIV agents with dramatically enhanced solubility.
    Bioorganic & medicinal chemistry letters, 2013, Sep-15, Volume: 23, Issue:18

    Topics: Anti-HIV Agents; Cell Line, Transformed; Cell Proliferation; Dose-Response Relationship, Drug; HIV-1; Humans; Hydrazines; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Solubility; Structure-Activity Relationship

2013
From human immunodeficiency virus non-nucleoside reverse transcriptase inhibitors to potent and selective antitrypanosomal compounds.
    Bioorganic & medicinal chemistry, 2014, Oct-01, Volume: 22, Issue:19

    Topics: Anti-HIV Agents; Cell Line; Cell Survival; Dose-Response Relationship, Drug; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Parasitic Sensitivity Tests; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense

2014
The thiocarboxanilide nonnucleoside UC781 is a tight-binding inhibitor of HIV-1 reverse transcriptase.
    Biochemistry, 1997, Jun-24, Volume: 36, Issue:25

    Topics: Anilides; Benzodiazepinones; Furans; HIV Reverse Transcriptase; Kinetics; Nevirapine; Protein Binding; Pyridines; Reverse Transcriptase Inhibitors; Spectrometry, Fluorescence; Thioamides

1997
Human immunodeficiency virus type 1 reverse transcriptase dimer destabilization by 1-[Spiro[4"-amino-2",2" -dioxo-1",2" -oxathiole-5",3'-[2', 5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]]]-3-ethylthy mine.
    Biochemistry, 2000, Feb-15, Volume: 39, Issue:6

    Topics: Anilides; Anti-HIV Agents; Binding Sites; Chromatography, High Pressure Liquid; Dimerization; Enzyme Activation; Enzyme Stability; Furans; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Nevirapine; Protein Denaturation; Reverse Transcriptase Inhibitors; Spiro Compounds; Thioamides; Thymidine; Urea

2000
Long-term exposure of HIV type 1-infected cell cultures to combinations of the novel quinoxaline GW420867X with lamivudine, abacavir, and a variety of nonnucleoside reverse transcriptase inhibitors.
    AIDS research and human retroviruses, 2000, Apr-10, Volume: 16, Issue:6

    Topics: Alkynes; Anilides; Anti-HIV Agents; Benzoxazines; Cell Line; Cyclopropanes; Delavirdine; Dideoxynucleosides; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance, Microbial; Furans; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Microbial Sensitivity Tests; Mutation; Nevirapine; Oxazines; Quinoxalines; Reverse Transcriptase Inhibitors; Thioamides; Uracil

2000
Human immunodeficiency virus type 1 resistance or cross-resistance to nonnucleoside reverse transcriptase inhibitors currently under development as microbicides.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:4

    Topics: Alkynes; Anilides; Anti-Infective Agents; Benzoxazines; Cell Line; Cells, Cultured; Cyclopropanes; Delavirdine; Drug Resistance, Viral; Furans; Genotype; HIV-1; Humans; Nevirapine; Reverse Transcriptase Inhibitors; Thiazoles; Thioamides; Thiourea

2011