nevirapine and l 737126

nevirapine has been researched along with l 737126 in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's5 (71.43)29.6817
2010's0 (0.00)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Balani, SK; Ciccarone, TM; Condra, JH; Emini, EA; Goldman, ME; Greenlee, WJ; Kauffman, LR; MacTough, SC; Rooney, CS; Williams, TM1
Artico, M; De Martino, G; La Colla, P; La Regina, G; Loi, AG; Marceddu, T; Massa, S; Mura, M; Silvestri, R; Vargiu, L1
Artico, M; De Martino, G; La Colla, M; La Colla, P; La Regina, G; Loddo, R; Mura, M; Silvestri, R1
Artico, M; Coluccia, A; De Martino, G; Di Pasquali, A; La Regina, G; Ragno, R; Silvestri, R1
Artico, M; Bergamini, A; Ciaprini, C; Coluccia, A; Crespan, E; De Martino, G; La Regina, G; Lavecchia, A; Maga, G; Novellino, E; Piscitelli, F; Ragno, R; Silvestri, R; Sinistro, A1
Chou, KC; González-Díaz, H; Martinez de la Vega, O; Prado-Prado, FJ; Ubeira, FM; Uriarte, E1
Armijos Rivera, JI; Badia, R; Brambilla, A; Catalano, M; Cinquina, E; Coluccia, A; Crespan, E; Esté, JA; Falasca, F; La Regina, G; Limatola, C; Maga, G; Masci, D; Nalli, M; Riveira-Muñoz, E; Silvestri, R; Turriziani, O1

Other Studies

7 other study(ies) available for nevirapine and l 737126

ArticleYear
5-chloro-3-(phenylsulfonyl)indole-2-carboxamide: a novel, non-nucleoside inhibitor of HIV-1 reverse transcriptase.
    Journal of medicinal chemistry, 1993, Apr-30, Volume: 36, Issue:9

    Topics: Animals; Antiviral Agents; Base Sequence; Biological Availability; HIV; HIV Reverse Transcriptase; HIV-1; Indoles; Macaca mulatta; Molecular Sequence Data; Molecular Structure; Reverse Transcriptase Inhibitors; Sulfoxides

1993
Novel indolyl aryl sulfones active against HIV-1 carrying NNRTI resistance mutations: synthesis and SAR studies.
    Journal of medicinal chemistry, 2003, Jun-05, Volume: 46, Issue:12

    Topics: Anti-HIV Agents; Cell Line; Drug Resistance, Viral; HIV-1; Humans; Indoles; Mutation; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Sulfones

2003
Simple, short peptide derivatives of a sulfonylindolecarboxamide (L-737,126) active in vitro against HIV-1 wild type and variants carrying non-nucleoside reverse transcriptase inhibitor resistance mutations.
    Journal of medicinal chemistry, 2004, Jul-15, Volume: 47, Issue:15

    Topics: Anti-HIV Agents; Cell Line; Drug Resistance, Viral; HIV-1; Humans; Indoles; Mutation; Reverse Transcriptase Inhibitors; Sulfones

2004
Docking and 3-D QSAR studies on indolyl aryl sulfones. Binding mode exploration at the HIV-1 reverse transcriptase non-nucleoside binding site and design of highly active N-(2-hydroxyethyl)carboxamide and N-(2-hydroxyethyl)carbohydrazide derivatives.
    Journal of medicinal chemistry, 2005, Jan-13, Volume: 48, Issue:1

    Topics: Binding Sites; Cells, Cultured; Drug Design; Drug Evaluation, Preclinical; HIV Reverse Transcriptase; Humans; Hydrazines; Microbial Sensitivity Tests; Models, Molecular; Nucleosides; Protein Conformation; Quantitative Structure-Activity Relationship; Reverse Transcriptase Inhibitors; Software; Sulfones

2005
Design, molecular modeling, synthesis, and anti-HIV-1 activity of new indolyl aryl sulfones. Novel derivatives of the indole-2-carboxamide.
    Journal of medicinal chemistry, 2006, Jun-01, Volume: 49, Issue:11

    Topics: Anti-HIV Agents; Cells, Cultured; Drug Design; Drug Resistance, Viral; HIV-1; Humans; Indoles; Lymphocytes; Macrophages; Models, Molecular; Pyrrolidinones; Quantitative Structure-Activity Relationship; Solubility; Sulfones

2006
Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks.
    Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2

    Topics: Anti-Infective Agents; Antiviral Agents; Artificial Intelligence; Computer Simulation; Drug Evaluation, Preclinical; Molecular Structure; Quantitative Structure-Activity Relationship

2009
New indolylarylsulfone non-nucleoside reverse transcriptase inhibitors show low nanomolar inhibition of single and double HIV-1 mutant strains.
    European journal of medicinal chemistry, 2020, Dec-15, Volume: 208

    Topics: Anti-HIV Agents; Cell Line, Tumor; Drug Design; Drug Synergism; HIV Reverse Transcriptase; HIV-1; Humans; Indoles; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Mutation; Protein Binding; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Sulfones; Zidovudine

2020