Compounds > nevirapine

nevirapine and l-697661

nevirapine has been researched along with l-697661 in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's21 (91.30)18.2507
2000's2 (8.70)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bamberger, DL; Fisher, TE; Goldman, ME; Hoffman, JM; Jones, JH; Rooney, CS; Saari, WS; Smith, AM; Thomas, CM; Wai, JS1
Fisher, TE; Goldman, ME; Hoffman, JM; Nunberg, JH; O'Brien, JA; Rooney, CS; Saari, WS; Smith, AM; Thomas, CM; Wai, JS1
Bethell, RC; Cammack, N; Green, DV; Hancock, AP; Hann, MM; Lamont, RB; Livermore, DG; Noble, SA; Orr, DC; Payne, JJ1
Ball, RG; Britcher, SF; Goldman, ME; Lumma, WC; Lyle, TA; O'Brien, JA; Sanders, WM; Tucker, TJ; Wiscount, CM; Young, SD1
Bethell, RC; Cammack, N; Charon, D; Dodic, N; Dumaitre, B; Evans, DN; Green, DV; Hopewell, PL; Humber, DC; Wyatt, PG1
Bamberger, DL; Fisher, TE; Hoffman, JM; Hudcosky, RJ; MacTough, SC; Rooney, CS; Saari, WS; Thomas, CM; Wai, JS; Williams, TM1
Balani, SK; Ciccarone, TM; Condra, JH; Emini, EA; Goldman, ME; Greenlee, WJ; Kauffman, LR; MacTough, SC; Rooney, CS; Williams, TM1
Althaus, IW; Biles, C; Busso, M; Genin, MJ; Morge, RA; Resnick, L; Reusser, F; Romero, DL; Tarpley, WG; Thomas, RC1
Kampe, W; König, B; Leinert, H; Leser, U; Mertens, A; Poll, T; Schäfer, W; Seidel, H; Zilch, H1
Bell, FW; Cantrell, AS; Högberg, M; Jaskunas, SR; Johansson, NG; Jordan, CL; Kinnick, MD; Lind, P; Morin, JM; Noréen, R1
Altamura, S; Campiani, G; De Filippis, MP; Di Renzo, L; Fiorini, I; Garofalo, A; Greco, G; Nacci, V; Novellino, E1
Adams, WJ; Biles, C; Evans, DB; Friis, JM; Hosley, JD; Keiser, BJ; Kopta, LA; Morge, RA; Morris, J; Olmsted, RA; Poel, TJ; Romero, DL; Sharma, SK; Stefanski, KJ; Stehle, RG; Tarpley, WG; Thomas, RC; Voorman, RL; Wishka, DG; Yagi, Y1
Cantrell, AS; Engelhardt, P; Högberg, M; Jaskunas, SR; Johansson, NG; Jordan, CL; Kangasmetsä, J; Kinnick, MD; Lind, P; Morin, JM; Muesing, MA; Noreén, R; Oberg, B; Pranc, P; Sahlberg, C; Ternansky, RJ; Vasileff, RT; Vrang, L; West, SJ; Zhang, H1
Engelhardt, P; Högberg, M; Kangasmetsä, J; Noréen, R; Sahlberg, C; Vrang, L; Zhang, H1
Biles, C; Genin, MJ; Keiser, BJ; Poppe, SM; Romero, DL; Swaney, SM; Tarpley, WG; Yagi, Y1
Dornadula, G; Grobler, JA; Hazuda, DJ; Miller, MD; Rice, MR; Simcoe, AL1
Condra, JH; Emini, EA; Gotlib, L; Graham, DJ; Lineberger, DW; Long, WJ; Sardana, VV; Schlabach, AJ; Wolfgang, JA1
Bender, R; Kirsch, R; Kleim, JP; Meichsner, C; Paessens, A; Riess, G1
Byrnes, VW; Condra, JH; Emini, EA; Sardana, VV; Schleif, WA1
Bäckbro, K; Noréen, R; Oberg, B; Unge, T; Vrang, L; Zhang, H1
Evans, DB; Fan, N; Rank, KB; Sharma, SK; Tarpley, WG; Thomas, RC1
Chen, IS; Dueweke, TJ; Poppe, SM; Pushkarskaya, T; Stevenson, M; Swaney, SM; Tarpley, WG; Zhao, JQ1
Kilby, JM; Saag, MS1

Reviews

2 review(s) available for nevirapine and l-697661

ArticleYear
The genetic and functional basis of HIV-1 resistance to nonnucleoside reverse transcriptase inhibitors.
    Archives of virology. Supplementum, 1994, Volume: 9

    Topics: Antiviral Agents; Benzodiazepines; Benzoxazoles; Clinical Trials as Topic; Drug Resistance, Microbial; Genetic Variation; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Imidazoles; Nevirapine; Pyridines; Pyridones; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase

1994
Clinical experience with non-nucleoside reverse transcriptase inhibitors: L-697,661 and nevirapine.
    Advances in experimental medicine and biology, 1996, Volume: 394

    Topics: Benzoxazoles; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Nevirapine; Pyridines; Pyridones; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase

1996

Other Studies

21 other study(ies) available for nevirapine and l-697661

ArticleYear
Synthesis and evaluation of 2-pyridinone derivatives as HIV-1-specific reverse transcriptase inhibitors. 2. Analogues of 3-aminopyridin-2(1H)-one.
    Journal of medicinal chemistry, 1992, Oct-16, Volume: 35, Issue:21

    Topics: Aminopyridines; Antiviral Agents; Benzoxazoles; Cells, Cultured; HIV Reverse Transcriptase; HIV-1; Pyridones; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

1992
2-Pyridinone derivatives: a new class of nonnucleoside, HIV-1-specific reverse transcriptase inhibitors.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:9

    Topics: Antiviral Agents; HIV-1; Pyridones; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase

1991
Synthesis and anti-HIV-1 activity of a series of imidazo[1,5-b]pyridazines.
    Journal of medicinal chemistry, 1993, Nov-26, Volume: 36, Issue:24

    Topics: Antiviral Agents; Cell Division; Cell Line; Crystallization; HIV Reverse Transcriptase; HIV-1; Imidazoles; Molecular Structure; Pyridazines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Virus Replication; Zidovudine

1993
Synthesis of a series of 4-(arylethynyl)-6-chloro-4-cyclopropyl-3,4-dihydroquinazolin-2(1H)-ones as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.
    Journal of medicinal chemistry, 1994, Jul-22, Volume: 37, Issue:15

    Topics: Cells, Cultured; Crystallography, X-Ray; HIV Reverse Transcriptase; HIV-1; Humans; Quinazolines; Reverse Transcriptase Inhibitors

1994
Benzophenone derivatives: a novel series of potent and selective inhibitors of human immunodeficiency virus type 1 reverse transcriptase.
    Journal of medicinal chemistry, 1995, May-12, Volume: 38, Issue:10

    Topics: Benzophenones; Cell Line; Crystallography, X-Ray; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

1995
Synthesis and evaluation of 2-pyridinone derivatives as specific HIV-1 reverse transcriptase inhibitors. 3. Pyridyl and phenyl analogs of 3-aminopyridin-2(1H)-one.
    Journal of medicinal chemistry, 1993, Jan-22, Volume: 36, Issue:2

    Topics: Aminopyridines; Animals; Antiviral Agents; Cells, Cultured; Haplorhini; HIV Reverse Transcriptase; Pyridones; Rats; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

1993
5-chloro-3-(phenylsulfonyl)indole-2-carboxamide: a novel, non-nucleoside inhibitor of HIV-1 reverse transcriptase.
    Journal of medicinal chemistry, 1993, Apr-30, Volume: 36, Issue:9

    Topics: Animals; Antiviral Agents; Base Sequence; Biological Availability; HIV; HIV Reverse Transcriptase; HIV-1; Indoles; Macaca mulatta; Molecular Sequence Data; Molecular Structure; Reverse Transcriptase Inhibitors; Sulfoxides

1993
Bis(heteroaryl)piperazine (BHAP) reverse transcriptase inhibitors: structure-activity relationships of novel substituted indole analogues and the identification of 1-[(5-methanesulfonamido-1H-indol-2-yl)-carbonyl]-4-[3- [(1-methylethyl)amino]-pyridinyl]pi
    Journal of medicinal chemistry, 1993, May-14, Volume: 36, Issue:10

    Topics: Antiviral Agents; Delavirdine; Indoles; Piperazines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Virus Replication

1993
Selective non-nucleoside HIV-1 reverse transcriptase inhibitors. New 2,3-dihydrothiazolo[2,3-a]isoindol-5(9bH)-ones and related compounds with anti-HIV-1 activity.
    Journal of medicinal chemistry, 1993, Aug-20, Volume: 36, Issue:17

    Topics: Animals; Antiviral Agents; Cells, Cultured; HIV Reverse Transcriptase; Indoles; Rats; Reverse Transcriptase Inhibitors; Stereoisomerism; Structure-Activity Relationship; Thiazoles

1993
Phenethylthiazolethiourea (PETT) compounds, a new class of HIV-1 reverse transcriptase inhibitors. 1. Synthesis and basic structure-activity relationship studies of PETT analogs.
    Journal of medicinal chemistry, 1995, Dec-08, Volume: 38, Issue:25

    Topics: Animals; Antiviral Agents; Cell Line; HIV-1; Humans; Isothiocyanates; Rats; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thiazoles; Thiourea

1995
Pyrrolobenzothiazepinones and pyrrolobenzoxazepinones: novel and specific non-nucleoside HIV-1 reverse transcriptase inhibitors with antiviral activity.
    Journal of medicinal chemistry, 1996, Jul-05, Volume: 39, Issue:14

    Topics: Antiviral Agents; Cell Line; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Molecular Structure; Oxazepines; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Structure-Activity Relationship; Thiazepines

1996
Targeting delavirdine/atevirdine resistant HIV-1: identification of (alkylamino)piperidine-containing bis(heteroaryl)piperazines as broad spectrum HIV-1 reverse transcriptase inhibitors.
    Journal of medicinal chemistry, 1996, Sep-13, Volume: 39, Issue:19

    Topics: Animals; Anti-HIV Agents; Biological Availability; Cell Line; Delavirdine; Drug Resistance, Microbial; Drug Stability; HIV Reverse Transcriptase; HIV-1; Indoles; Molecular Structure; Piperazines; Piperidines; Pyridines; Rats; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

1996
Phenethylthiazolylthiourea (PETT) compounds as a new class of HIV-1 reverse transcriptase inhibitors. 2. Synthesis and further structure-activity relationship studies of PETT analogs.
    Journal of medicinal chemistry, 1996, Oct-11, Volume: 39, Issue:21

    Topics: Animals; Anti-HIV Agents; Cells, Cultured; HIV Reverse Transcriptase; Intercalating Agents; Structure-Activity Relationship; Thiazoles; Thiourea

1996
Synthesis and anti-HIV activities of urea-PETT analogs belonging to a new class of potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
    Bioorganic & medicinal chemistry letters, 1998, Jun-16, Volume: 8, Issue:12

    Topics: Anti-HIV Agents; Blood Proteins; Cell Line; HIV-1; Humans; Microbial Sensitivity Tests; Protein Binding; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thiazoles; Triazoles

1998
Novel 1,5-diphenylpyrazole nonnucleoside HIV-1 reverse transcriptase inhibitors with enhanced activity versus the delavirdine-resistant P236L mutant: lead identification and SAR of 3- and 4-substituted derivatives.
    Journal of medicinal chemistry, 2000, Mar-09, Volume: 43, Issue:5

    Topics: Anti-HIV Agents; Delavirdine; Drug Resistance, Microbial; HIV Reverse Transcriptase; Mutation; Pyrazoles; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2000
HIV-1 reverse transcriptase plus-strand initiation exhibits preferential sensitivity to non-nucleoside reverse transcriptase inhibitors in vitro.
    The Journal of biological chemistry, 2007, Mar-16, Volume: 282, Issue:11

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Benzoxazoles; Cyclopropanes; DNA; Dose-Response Relationship, Drug; Drug Resistance, Viral; Enzyme Inhibitors; HIV Reverse Transcriptase; In Vitro Techniques; Inhibitory Concentration 50; Ligands; Models, Genetic; Oxazines; Pyridones; Reverse Transcriptase Inhibitors; Stochastic Processes; Transcription, Genetic; Virus Replication

2007
Functional analysis of HIV-1 reverse transcriptase amino acids involved in resistance to multiple nonnucleoside inhibitors.
    The Journal of biological chemistry, 1992, Sep-05, Volume: 267, Issue:25

    Topics: Amino Acid Sequence; Antiviral Agents; Azepines; Benzodiazepines; Benzoxazoles; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Imidazoles; Kinetics; Mutagenesis, Site-Directed; Nevirapine; Pyridines; Pyridones; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Structure-Activity Relationship

1992
Mutational analysis of residue 190 of human immunodeficiency virus type 1 reverse transcriptase.
    Virology, 1994, May-01, Volume: 200, Issue:2

    Topics: Antiviral Agents; Base Sequence; Benzodiazepines; Benzoxazoles; Delavirdine; DNA Mutational Analysis; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Imidazoles; Indoles; Molecular Sequence Data; Mutagenesis, Site-Directed; Nevirapine; Piperazines; Pyridines; Pyridones; Quinoxalines; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Selection, Genetic; Structure-Activity Relationship

1994
Enzymatic properties and sensitivity to inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase with Glu-138-->Arg and Tyr-188-->His mutations.
    Antiviral research, 1994, Volume: 24, Issue:1

    Topics: Amino Acids; Antiviral Agents; Base Sequence; Benzodiazepines; Benzoxazoles; Binding, Competitive; Deoxyguanine Nucleotides; Dideoxynucleotides; Foscarnet; HIV Reverse Transcriptase; Humans; Imidazoles; Kinetics; Molecular Sequence Data; Mutation; Nevirapine; Pyridines; Pyridones; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Sensitivity and Specificity

1994
Simultaneous mutations at Tyr-181 and Tyr-188 in HIV-1 reverse transcriptase prevents inhibition of RNA-dependent DNA polymerase activity by the bisheteroarylpiperazine (BHAP) U-90152s.
    FEBS letters, 1995, Aug-14, Volume: 370, Issue:1-2

    Topics: Amino Acid Sequence; Antiviral Agents; Benzodiazepines; Benzoxazoles; Cloning, Molecular; Delavirdine; HIV Reverse Transcriptase; HIV-1; HIV-2; Imidazoles; Indoles; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Nevirapine; Piperazines; Point Mutation; Pyridines; Pyridones; Recombinant Fusion Proteins; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Tyrosine

1995
A mutation in reverse transcriptase of bis(heteroaryl)piperazine-resistant human immunodeficiency virus type 1 that confers increased sensitivity to other nonnucleoside inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, May-15, Volume: 90, Issue:10

    Topics: Antiviral Agents; Base Sequence; Benzodiazepines; Benzoxazoles; Cloning, Molecular; Delavirdine; Drug Resistance; HIV Reverse Transcriptase; Imidazoles; Indoles; Molecular Sequence Data; Mutation; Nevirapine; Oligodeoxyribonucleotides; Piperazines; Pyridines; Pyridones; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase

1993