Compounds > nevirapine

nevirapine and fluconazole

nevirapine has been researched along with fluconazole in 19 studies

Research

Studies (19)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	9 (47.37)	29.6817
2010's	10 (52.63)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Duffy, EM; Jorgensen, WL	1
Topliss, JG; Yoshida, F	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bala, V; Bhatta, RS; Chandasana, H; Chhonker, YS; Gupta, G; Gupta, S; Jangir, S; Krishna, A; Krishna, S; Kushwaha, B; Maikhuri, JP; Mandalapu, D; Rawat, K; Sankhwar, SN; Sharma, VL; Shukla, PK; Siddiqi, MI; Singh, M; Tripathi, R	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Igarashi, T; Ishiguro, N; Kishimoto, W; Sakai, K; Senda, C; Takano, J	1
Chaovavanich, A; Chumpathat, N; Manosuthi, W; Sungkanuparph, S	1
Athichathanabadi, C; Manosuthi, W; Phoorisri, T; Sungkanuparph, S; Uttayamakul, S	1
Ggayi, AB; Khoo, S; Lalloo, DG; Parkes-Ratanshi, R; Wakeham, K; Watson, V	1
Boulware, DR	1

Reviews

1 review(s) available for nevirapine and fluconazole

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for nevirapine and fluconazole

Article	Year
Co-administration of fluconazole increases nevirapine concentrations in HIV-infected Ugandans. The Journal of antimicrobial chemotherapy, 2010, Volume: 65, Issue:2 Topics: Adult; Anti-HIV Agents; Antifungal Agents; Cryptococcosis; Drug Interactions; Female; Fluconazole; HIV Infections; Humans; Male; Nevirapine; Placebos; Plasma; Uganda	2010

Other Studies

17 other study(ies) available for nevirapine and fluconazole

Article	Year
Prediction of drug solubility from Monte Carlo simulations. Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11 Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
N-Alkyl/aryl-4-(3-substituted-3-phenylpropyl)piperazine-1-carbothioamide as dual-action vaginal microbicides with reverse transcriptase inhibition. European journal of medicinal chemistry, 2015, Aug-28, Volume: 101 Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Dose-Response Relationship, Drug; Female; HeLa Cells; Humans; Lactobacillus acidophilus; Male; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Parasitic Sensitivity Tests; Piperazines; Rabbits; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Spermatocidal Agents; Spermatozoa; Structure-Activity Relationship; Thioamides; Trichomonas vaginalis; Vagina	2015
Quantitative prediction of in vivo drug interactions between nevirapine and antifungal agents from in vitro data in rats. Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:9 Topics: Albumins; Animals; Anti-HIV Agents; Antifungal Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Fluconazole; Ketoconazole; Male; Microsomes, Liver; Nevirapine; Oxidoreductases, N-Demethylating; Rats; Rats, Sprague-Dawley	2000
South Africa cuts agreement for one AIDS drug but ignores another. IAPAC monthly, 2001, Volume: 7, Issue:2 Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Cost Savings; Drug Industry; Female; Fluconazole; Humans; Infant, Newborn; Male; Nevirapine; Pregnancy; South Africa	2001
Safety and tolerability of nevirapine-based antiretroviral therapy in HIV-infected patients receiving fluconazole for cryptococcal prophylaxis: a retrospective cohort study. BMC infectious diseases, 2005, Aug-24, Volume: 5 Topics: Adult; Alanine Transaminase; Anti-HIV Agents; Antifungal Agents; Antiretroviral Therapy, Highly Active; Aspartate Aminotransferases; Cohort Studies; Female; Fluconazole; HIV Infections; Humans; Logistic Models; Male; Middle Aged; Nevirapine; Odds Ratio; Retrospective Studies; Risk Factors	2005
Plasma nevirapine levels, adverse events and efficacy of antiretroviral therapy among HIV-infected patients concurrently receiving nevirapine-based antiretroviral therapy and fluconazole. BMC infectious diseases, 2007, Mar-12, Volume: 7 Topics: Anti-HIV Agents; Antifungal Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; Fluconazole; HIV Infections; Humans; Male; Nevirapine; Pregnancy	2007
Safety, censoring, and intent-to-treat analysis: dangers to generalizability. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2010, Oct-15, Volume: 51, Issue:8 Topics: Acquired Immunodeficiency Syndrome; Africa South of the Sahara; Alanine Transaminase; Anti-HIV Agents; Antifungal Agents; Antiretroviral Therapy, Highly Active; Fluconazole; Humans; Liver; Liver Function Tests; Meningitis, Cryptococcal; Nevirapine	2010