nevirapine and emivirine

nevirapine has been researched along with emivirine in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (38.10)18.2507
2000's9 (42.86)29.6817
2010's4 (19.05)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Artico, M; Greco, G; La Colla, P; Loi, AG; Mai, A; Marongiu, ME; Massa, S; Novellino, E; Sbardella, G; Tramontano, E1
Mao, C; Sudbeck, EA; Uckun, FM; Venkatachalam, TK1
Maher, D; Mao, C; Pendergrass, S; Tuel-Ahlgren, L; Uckun, FM; Venkatachalam, TK; Zhu, D2
Jorgensen, WL; Rizzo, RC; Tirado-Rives, J1
Artico, M; Greco, G; La Colla, M; La Colla, P; Lavecchia, A; Loddo, R; Mai, A; Massa, S; Murgioni, C; Musiu, C; Novellino, E; Ragno, R; Sbardella, G1
Jorgensen, WL; Rizzo, RC; Tirado-Rives, J; Wang, DP1
Jorgensen, WL; Kroeger Smith, MB; Rizzo, RC; Smith, RH; Tirado-Rives, J; Udier-Blagović, M; Wang, DP; Watkins, EK1
Andries, K; Benjahad, A; Grierson, DS; Guillemont, J; Nguyen, CH1
Artico, M; Cadeddu, A; La Colla, P; Mai, A; Marturana, F; Massa, S; Mura, M; Musiu, C; Ragno, R; Sbardella, G1
Andries, K; Benjahad, A; Bisagni, E; Coupa, S; Courté, K; Csoka, I; de Béthune, MP; Grierson, DS; Guillemont, J; Mabire, D; Monneret, C; Nguyen, CH; Pauwels, R; Poncelet, A1
Kang, X; Kollman, PA; Kuntz, ID; Wang, J1
Cui, Y; Guo, Y; Liu, C; Liu, J; Ma, L; Qin, H; Wang, R; Wang, X; Zhang, J; Zhang, Z1
Huang, Y; Jiang, S; Li, L; Liu, C; Liu, J; Ma, L; Ouyang, Y; Qiao, K; Shao, Y; Wang, R; Wang, X; Xu, W; Zhang, J; Zhang, L; Zhang, Z1
Collu, G; Giliberti, G; La Colla, P; Loddo, R; Loksha, YM; Pedersen, EB; Sanna, G1
Brennan, TM; Bridges, CG; Leyda, JP; Taylor, DL; Tyms, AS1
Baba, M; Makino, M; Nakade, K; Okamoto, M; Yamada, K; Yuasa, S1
Griffith, R; Keller, PA; Titmuss, SJ1
Crowe, S1
Balzarini, J; Burt, V; Carbonez, A; De Clercq, E; Kleim, JP1
Decha, P; Hannongbua, S; Intharathep, P; Parasuk, V; Sompornpisut, P; Udommaneethanakit, T; Wolschann, P1

Reviews

1 review(s) available for nevirapine and emivirine

ArticleYear
New reverse transcriptase inhibitors.
    Advances in experimental medicine and biology, 1999, Volume: 458

    Topics: Adenine; Alkynes; Benzoxazines; Cyclopropanes; Delavirdine; Dideoxynucleosides; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Nevirapine; Organophosphonates; Oxazines; Prodrugs; Reverse Transcriptase Inhibitors; Soman; Uracil

1999

Other Studies

20 other study(ies) available for nevirapine and emivirine

ArticleYear
5-Alkyl-2-(alkylthio)-6-(2,6-dihalophenylmethyl)-3, 4-dihydropyrimidin-4(3H)-ones: novel potent and selective dihydro-alkoxy-benzyl-oxopyrimidine derivatives.
    Journal of medicinal chemistry, 1999, Feb-25, Volume: 42, Issue:4

    Topics: Animals; Anti-HIV Agents; Cell Line; Cell Survival; Drug Design; HIV Reverse Transcriptase; HIV-1; Mice; Models, Molecular; Pyrimidines; Recombinant Proteins; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

1999
Rational design of N-[2-(2,5-dimethoxyphenylethyl)]-N'-[2-(5-bromopyridyl)]-thiourea (HI-236) as a potent non-nucleoside inhibitor of drug-resistant human immunodeficiency virus.
    Bioorganic & medicinal chemistry letters, 1999, Jun-07, Volume: 9, Issue:11

    Topics: Anti-HIV Agents; Delavirdine; Drug Design; Humans; Inhibitory Concentration 50; Kinetics; Models, Molecular; Nevirapine; Pyridines; Thiourea

1999
N-[2-(1-cyclohexenyl)ethyl]-N'-[2-(5-bromopyridyl)]-thiourea and N'-[2-(1-cyclohexenyl)ethyl]-N'-[2-(5-chloropyridyl)]-thiourea as potent inhibitors of multidrug-resistant human immunodeficiency virus-1.
    Bioorganic & medicinal chemistry letters, 1999, Sep-20, Volume: 9, Issue:18

    Topics: Aminopyridines; Anti-HIV Agents; Drug Resistance, Microbial; Drug Resistance, Multiple; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Reverse Transcriptase Inhibitors; Thiourea

1999
N'-[2-(2-thiophene)ethyl]-N'-[2-(5-bromopyridyl)] thiourea as a potent inhibitor of NNI-resistant and multidrug-resistant human immunodeficiency virus-1.
    Bioorganic & medicinal chemistry letters, 1999, Dec-20, Volume: 9, Issue:24

    Topics: Anti-HIV Agents; Cells, Cultured; HIV-1; Humans; Microbial Sensitivity Tests; Models, Molecular; Pyridines; Reverse Transcriptase Inhibitors; Thiourea; Virus Replication

1999
Estimation of binding affinities for HEPT and nevirapine analogues with HIV-1 reverse transcriptase via Monte Carlo simulations.
    Journal of medicinal chemistry, 2001, Jan-18, Volume: 44, Issue:2

    Topics: Anti-HIV Agents; HIV Reverse Transcriptase; Models, Molecular; Monte Carlo Method; Nevirapine; Protein Binding; Pyrimidinones; Regression Analysis; Reverse Transcriptase Inhibitors; Thermodynamics; Uracil

2001
Structure-based design, synthesis, and biological evaluation of conformationally restricted novel 2-alkylthio-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
    Journal of medicinal chemistry, 2001, Aug-02, Volume: 44, Issue:16

    Topics: Animals; Cell Line; Drug Design; HIV Reverse Transcriptase; HIV-1; Models, Molecular; Molecular Conformation; Mutation; Pyrimidines; Pyrimidinones; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2001
Antiviral drug design: computational analyses of the effects of the L100I mutation for HIV-RT on the binding of NNRTIs.
    Bioorganic & medicinal chemistry letters, 2001, Nov-05, Volume: 11, Issue:21

    Topics: Drug Design; HIV Reverse Transcriptase; Models, Molecular; Mutation; Reverse Transcriptase Inhibitors

2001
Prediction of activity for nonnucleoside inhibitors with HIV-1 reverse transcriptase based on Monte Carlo simulations.
    Journal of medicinal chemistry, 2002, Jul-04, Volume: 45, Issue:14

    Topics: Alkynes; Anilides; Benzoxazines; Computer Simulation; Cyclopropanes; HIV Reverse Transcriptase; Hydrogen Bonding; Models, Molecular; Monte Carlo Method; Nevirapine; Oxazines; Protein Binding; Quinoxalines; Regression Analysis; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Uracil

2002
3-iodo-4-phenoxypyridinones (IOPY's), a new family of highly potent non-nucleoside inhibitors of HIV-1 reverse transcriptase.
    Bioorganic & medicinal chemistry letters, 2003, Dec-15, Volume: 13, Issue:24

    Topics: HIV-1; Models, Molecular; Molecular Conformation; Pyridones; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2003
Computer-aided design, synthesis, and anti-HIV-1 activity in vitro of 2-alkylamino-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as novel potent non-nucleoside reverse transcriptase inhibitors, also active against the Y181C varia
    Journal of medicinal chemistry, 2004, Feb-12, Volume: 47, Issue:4

    Topics: Cell Line; Computer Simulation; Drug Design; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Models, Molecular; Mutation; Pyrimidinones; Quantitative Structure-Activity Relationship; Reverse Transcriptase Inhibitors

2004
4-benzyl- and 4-benzoyl-3-dimethylaminopyridin-2(1H)-ones, a new family of potent anti-HIV agents: optimization and in vitro evaluation against clinically important HIV mutant strains.
    Journal of medicinal chemistry, 2004, Oct-21, Volume: 47, Issue:22

    Topics: Alkynes; Aminopyridines; Anti-HIV Agents; Benzene Derivatives; Benzoates; Benzoxazines; Cell Line; Cyclopropanes; HIV-1; Humans; Mutagenesis, Site-Directed; Mutation; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Uracil

2004
Hierarchical database screenings for HIV-1 reverse transcriptase using a pharmacophore model, rigid docking, solvation docking, and MM-PB/SA.
    Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7

    Topics: Allosteric Site; Anti-HIV Agents; Crystallography, X-Ray; Databases, Factual; Drug Design; HIV Reverse Transcriptase; Models, Molecular; Molecular Conformation; Molecular Structure; Protein Binding; Quantitative Structure-Activity Relationship; Reverse Transcriptase Inhibitors; Statistics as Topic; Thermodynamics

2005
Synthesis and biological evaluation of novel C5 halogen-functionalized S-DABO as potent HIV-1 non-nucleoside reverse transcriptase inhibitors.
    Bioorganic & medicinal chemistry, 2010, May-01, Volume: 18, Issue:9

    Topics: Drug Design; Halogens; HIV Reverse Transcriptase; HIV-1; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Molecular Structure; Nevirapine; Pyrimidinones; Quantitative Structure-Activity Relationship; Reverse Transcriptase Inhibitors; Sulfur

2010
Design, synthesis, and biological evaluation of 1-[(2-benzyloxyl/alkoxyl)methyl]-5-halo-6-aryluracils as potent HIV-1 non-nucleoside reverse transcriptase inhibitors with an improved drug resistance profile.
    Journal of medicinal chemistry, 2012, Mar-08, Volume: 55, Issue:5

    Topics: Anti-HIV Agents; Cell Line, Tumor; Drug Design; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Hydrogen Bonding; Models, Molecular; Structure-Activity Relationship; Uracil

2012
Synthesis of novel fluoro analogues of MKC442 as microbicides.
    Journal of medicinal chemistry, 2014, Jun-26, Volume: 57, Issue:12

    Topics: Anti-HIV Agents; Cell Line; Drug Resistance, Viral; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Pyrimidinones; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Uracil

2014
The inhibition of human immunodeficiency virus type 1 in vitro by a non-nucleoside reverse transcriptase inhibitor MKC-442, alone and in combination with other anti-HIV compounds.
    Antiviral research, 1995, Volume: 26, Issue:2

    Topics: Antiviral Agents; Cells, Cultured; Cytotoxicity Tests, Immunologic; Didanosine; Drug Interactions; HIV Reverse Transcriptase; HIV-1; Humans; Indolizines; Isoquinolines; Leukocytes, Mononuclear; Molecular Structure; Nevirapine; Pyridines; Quinolines; Reverse Transcriptase Inhibitors; Saquinavir; Uracil; Zalcitabine; Zidovudine

1995
Complete inhibition of viral breakthrough by combination of MKC-442 with AZT during a long-term culture of HIV-1 infected cells.
    Antiviral research, 1996, Volume: 31, Issue:1-2

    Topics: Acetamides; Acetophenones; Cell Line, Transformed; HIV; HIV Core Protein p24; HIV-1; Humans; Nevirapine; Pyridines; Reverse Transcriptase Inhibitors; Uracil; Zidovudine

1996
Docking experiments in the flexible non-nucleoside inhibitor binding pocket of HIV-1 reverse transcriptase.
    Bioorganic & medicinal chemistry, 1999, Volume: 7, Issue:6

    Topics: Binding Sites; Databases, Factual; HIV; HIV Reverse Transcriptase; Ligands; Molecular Structure; Nevirapine; Protein Conformation; Reproducibility of Results; Reverse Transcriptase Inhibitors; Uracil

1999
Long-term exposure of HIV type 1-infected cell cultures to combinations of the novel quinoxaline GW420867X with lamivudine, abacavir, and a variety of nonnucleoside reverse transcriptase inhibitors.
    AIDS research and human retroviruses, 2000, Apr-10, Volume: 16, Issue:6

    Topics: Alkynes; Anilides; Anti-HIV Agents; Benzoxazines; Cell Line; Cyclopropanes; Delavirdine; Dideoxynucleosides; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance, Microbial; Furans; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Microbial Sensitivity Tests; Mutation; Nevirapine; Oxazines; Quinoxalines; Reverse Transcriptase Inhibitors; Thioamides; Uracil

2000
Theoretical studies on the molecular basis of HIV-1RT/NNRTIs interactions.
    Journal of enzyme inhibition and medicinal chemistry, 2011, Volume: 26, Issue:1

    Topics: Alkynes; Amino Acids; Benzoxazines; Binding Sites; Cyclopropanes; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Models, Biological; Molecular Dynamics Simulation; Mutation; Nevirapine; Nitriles; Protein Binding; Protein Conformation; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; Thermodynamics; Uracil; Water

2011