nevirapine and efavirenz

nevirapine has been researched along with efavirenz in 693 studies

Research

Studies (693)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	12 (1.73)	18.2507
2000's	311 (44.88)	29.6817
2010's	330 (47.62)	24.3611
2020's	40 (5.77)	2.80

Authors

Authors	Studies
Bäckbro, K; Engelhardt, P; Fridborg, K; Högberg, M; Johansson, NG; Kangasmetsä, J; Lövgren, S; Noréen, R; Oberg, B; Sahlberg, BL; Sahlberg, C; Unge, T; Vrang, L; Zhang, H	1
Corbett, JW; Cordova, BC; Erickson-Viitanen, SK; Gearhart, LA; Klabe, RM; Ko, SS; Rodgers, JD	1
Anderson, PS; Bacheler, LT; Corbett, JW; Cordova, BC; Diamond, S; Erickson-Viitanen, SK; Garber, S; Gearhart, LA; Jeffrey, S; Klabe, RM; Ko, SS; Logue, K; Magnus, NA; Rodgers, JD; Trainor, GL	1
Andrews , CW; Boone, LR; Chan, JH; Cowan, JR; Creech, KL; Ferris, RG; Hazen, RJ; Hong, JS; Hopkins, A; Hunter , RN; Orr, GF; Ott, RJ; Reitter, BE; Ren, J; Roberts, GB; Sherman, DB; Short, SA; Sparks, SM; St Clair, M; Stammers, DK; Stuart, DI; Weaver, K	1
Aiello, F; Armaroli, S; Bergamini, A; Bolacchi, F; Bongiovanni, B; Caccia, S; Campiani, G; Capozzi, M; Coletta, M; Fabbrini, M; Garofalo, A; Greco, G; Guiso, G; Maga, G; Marini, S; Morelli, E; Nacci, V; Novellino, E; Ramunno, A; Spadari, S; Ventura, L	1
Artico, M; Greco, G; La Colla, M; La Colla, P; Lavecchia, A; Loddo, R; Mai, A; Massa, S; Murgioni, C; Musiu, C; Novellino, E; Ragno, R; Sbardella, G	1
Andries, K; Arnold, E; Azijn, H; Daeyaert, FF; Das, K; de Béthune, MP; De Corte, BL; de Jonge, MR; Heeres, J; Ho, CY; Janssen, PA; Kavash, RW; Koymans, LM; Kukla, MJ; Lewi, PJ; Lichtenstein, MA; Ludovici, DW; Pauwels, R; Van Aken, KJ; Ye, H	1
Jorgensen, WL; Rizzo, RC; Tirado-Rives, J; Wang, DP	1
Jorgensen, WL; Kroeger Smith, MB; Rizzo, RC; Smith, RH; Tirado-Rives, J; Udier-Blagović, M; Wang, DP; Watkins, EK	1
Boel, AM; Dahan, B; El-Brollosy, NR; Jørgensen, PT; Nielsen, C; Pedersen, EB	1
Artico, M; De Martino, G; La Colla, P; La Regina, G; Loi, AG; Marceddu, T; Massa, S; Mura, M; Silvestri, R; Vargiu, L	1
Andries, K; Benjahad, A; Grierson, DS; Guillemont, J; Nguyen, CH	1
Artico, M; Cadeddu, A; La Colla, P; Mai, A; Marturana, F; Massa, S; Mura, M; Musiu, C; Ragno, R; Sbardella, G	1
Andrews, CW; Boone, LR; Chan, JH; Cowan, JR; Creech, KL; Ferris, RG; Freeman, GA; Gonzales, SS; Hazen, RJ; Koszalka, GW; Lowell, GS; Reynolds, DJ; Roberts, GB; Romines, KR; Schaller, LT; Short, SA; St Clair, M; Tidwell, JH; Weaver, K	1
Singh, SK; Yadav, A	1
Andries, K; Arnold, E; Boyer, PL; Clark, AD; Clark, P; Daeyaert, F; Das, K; De Béthune, MP; De Corte, B; De Jonge, MR; Heeres, J; Ho, CY; Hughes, SH; Janssen, PA; Kavash, RW; Koymans, LM; Kukla, MJ; Lewi, PJ; Lichtenstein, MA; Ludovici, DW; Pauwels, R; Vinkers, HM; Ye, H	1
Balzarini, J; Chen, F; De Clercq, E; He, Y; Pannecouque, C; Sun, G; Wang, Y	1
Artico, M; De Martino, G; La Colla, M; La Colla, P; La Regina, G; Loddo, R; Mura, M; Silvestri, R	1
Andries, K; Benjahad, A; Bisagni, E; Coupa, S; Courté, K; Csoka, I; de Béthune, MP; Grierson, DS; Guillemont, J; Mabire, D; Monneret, C; Nguyen, CH; Pauwels, R; Poncelet, A	1
Baba, M; Fujii, M; Fujiwara, M; Fujiyasu, J; Hatta, T; Inoue, H; Kageyama, S; Kodama, E; Koga, H; Kontani, T; Kurihara, H; Masuda, N; Matsuoka, M; Moritomo, A; Nakahara, H; Ohgami, T; Ohta, M; Orita, M; Shigeta, S; Shimizu, Y; Sudo, K; Suzuki, H; Yamamoto, O; Yokota, T	1
Andrews Iii, CW; Boone, LR; Chan, JH; Cowan, JR; Creech, KL; Ferris, RG; Freeman, GA; Gonzales, SS; Hazen, RJ; Hopkins, AL; Koszalka, GW; Lowell, GS; Milton, J; Ren, J; Reynolds, DJ; Roberts, GB; Schaller, LT; Short, SA; Stammers, DK; Stuart, DI; Weaver, K	1
Artico, M; Coluccia, A; De Martino, G; Di Pasquali, A; La Regina, G; Ragno, R; Silvestri, R	1
De Corte, BL	1
Andries, K; Arnold, E; Bohets, H; Clark, AD; Daeyaert, F; Das, K; de Béthune, MP; De Clerck, F; de Jonge, M; De Knaep, F; Frenkel, YV; Guillemont, J; Heeres, J; Hughes, SH; Janssen, PA; Koymans, L; Kukla, M; Lampo, A; Lewi, PJ; Ludovici, D; Medaer, B; Pasquier, E; Pauwels, R; Stoffels, P; Vinkers, M; Williams, P	1
Andries, K; Arnold, E; Benjahad, A; Bisagni, E; Coupa, S; Croisy, M; Csoka, I; Das, K; de Béthune, MP; Grierson, DS; Guillemont, J; Himmel, DM; Mabire, D; Meyer, C; Monneret, C; Nguyen, CH; Pauwels, R; Poncelet, A	1
Andries, K; Arnold, E; Bettens, E; Daeyaert, FF; Das, K; de Béthune, MP; de Jonge, MR; Gaurrand, S; Guillemont, J; Heeres, J; Hertogs, K; Janssen, PA; Koymans, LM; Lewi, PJ; Palandjian, P; Pasquier, E; Pauwels, R; Timmerman, P; Vernier, D; Vinkers, MH; Wigerinck, P	1
Kang, X; Kollman, PA; Kuntz, ID; Wang, J	1
Artico, M; Bergamini, A; Ciaprini, C; Crespan, E; De Martino, G; Di Pasquali, A; La Regina, G; Maga, G; Ragno, R; Silvestri, R; Sinistro, A	1
Artico, M; Bartolini, S; Mai, A; Paesano, N; Rotili, D; Sbardella, G; Spadafora, C	1
Bergamini, A; Butini, S; Campiani, G; Catalanotti, B; Coletta, M; De Angelis, M; Fattorusso, C; Fiorini, I; Gemma, S; Greco, G; Huleatt, P; Maga, G; Marini, S; Nacci, V; Novellino, E; Persico, M; Ramunno, A; Rodriquez, M; Spadari, S	1
Alongi, M; Armand-Ugón, M; Bernardini, C; Botta, M; Cancio, R; Carmi, C; Clotet-Codina, I; Corelli, F; Crespan, E; Esté, JA; Maga, G; Manetti, F; Massa, S; Mugnaini, C; Petricci, E; Togninelli, A	1
Andrews, CW; Boone, LR; Chan, JH; Cowan, JR; Ferris, RG; Freeman, GA; Gonzales, SS; Hazen, RJ; Romines, KR; Schaller, LT; Short, SA; Stammers, DK; Tidwell, JH	1
Bieza, K; Bursulaya, B; Caldwell, J; He, Y; Jiang, T; Karanewsky, D; Kuhen, KL; Tuntland, T; Wolff, K; Yin, H; Zhang, K	1
Bieza, K; Bursulaya, B; Caldwell, J; He, Y; Jiang, T; Kuhen, KL; Wolff, K; Wu, TY; Yin, H	1
Deschamps, J; Krajewski, K; Parrish, D; Pathak, VK; Roller, PP; Zhang, Y	1
Botta, M; Cancio, R; Clotet-Codina, I; Corelli, F; Esté, JA; Maga, G; Manetti, F; Mugnaini, C	1
Anaclerio, B; Bieza, K; Caldwell, J; Ellis, D; He, X; He, Y; Karanewsky, D; Kuhen, K; Ngoc Nguyen, T; Wolff, K; Wu, B; Yang, K; Yin, H	1
Artico, M; Bergamini, A; Ciaprini, C; Coluccia, A; Crespan, E; De Martino, G; La Regina, G; Lavecchia, A; Maga, G; Novellino, E; Piscitelli, F; Ragno, R; Silvestri, R; Sinistro, A	1
Bursulaya, B; He, Y; Kuhen, KL; Nguyen, DG; Nguyen, TN; Wang, Z; Wu, B	1
Anaclerio, B; Bursulaya, B; Caldwell, J; Ellis, D; He, Y; Karanewsky, D; Kuhen, KL; Wolff, K; Wu, B; Yin, H	1
Anderson, KS; Bailey, CM; Domaoal, RA; Hamilton, AD; Jorgensen, WL; Kim, JT; Thakur, VV; Wang, L	1
Caldwell, J; Gadhachanda, VR; Havenhand, M; He, Y; Kuhen, KL; Walter, H; Wang, Z; Wu, B; Zondler, H	1
Aguiar, RS; Brindeiro, RM; Costa, LJ; Pereira, HS; Tanuri, A	1
Girardet, JL; Hamatake, RK; Hong, Z; Koh, YH; Shim, JH; Xu, W; Yeh, LT; Zhang, Z	1
Haefeli, WE; Ketabi-Kiyanvash, N; Lindenmaier, H; Theile, D; Weiss, J	1
Dornadula, G; Grobler, JA; Hazuda, DJ; Miller, MD; Rice, MR; Simcoe, AL	1
Bettens, E; Demestre, C; Guillemont, J; Heeres, J; Hertogs, K; Lewi, P; Masungi, C; Mordant, C; Pasquier, E; Peeters, A; Queguiner, L; Schmitt, B; Smeulders, L	1
Balzarini, J; Barreca, ML; Chimirri, A; De Clercq, E; De Luca, L; Iraci, N; Maga, G; Monforte, AM; Pannecouque, C; Rao, A	1
Buckheit, RW; Clercq, ED; Cullen, MD; Cushman, M; Deng, BL; Hartman, TL; Pannecouque, C; Watson, KM	1
Artico, M; Bergamini, A; Cavazza, A; Coluccia, A; Maga, G; Novellino, E; Piscitelli, F; Regina, GL; Samuele, A; Silvestri, R; Sinistro, A; Zanoli, S	1
Armand-Ugón, M; Artico, M; Clotet-Codina, I; Esté, JA; Maga, G; Mai, A; Nawrozkij, MB; Ragno, R; Rotili, D; Samuele, A; Sbardella, G; Simeoni, S; Tarantino, D	1
Anderson, KS; Bailey, CM; Barreiro, G; Domaoal, RA; Guimarães, CR; Jorgensen, WL; Kim, JT; Wang, L	1
Alongi, M; Angeli, L; Armand-Ugón, M; Bellucci, L; Bernardini, C; Botta, M; Brizzi, A; Clotet-Codina, I; Corelli, F; Esté, JA; Facchini, M; Gevariya, H; Maga, G; Manetti, F; Massa, S; Mugnaini, C; Samuele, A; Tafi, A; Togninelli, A	1
Barreca, ML; Chimirri, A; De Clercq, E; De Luca, L; Ferro, S; Iraci, N; Logoteta, P; Maga, G; Monforte, AM; Pannecouque, C; Rao, A	1
Armand-Ugón, M; Artico, M; Botta, G; Clotet-Codina, I; Eremiychuk, AS; Esté, JA; Maga, G; Mai, A; Musmuca, I; Nawrozkij, MB; Novakov, IA; Orlinson, BS; Ragno, R; Rotili, D; Samuele, A; Tarantino, D; Zanoli, S	1
Andrews, CW; Boone, L; Chamberlain, PP; Chan, JH; Ferris, RG; Freeman, A; Hazen, R; Ren, J; Romines, KR; Short, SA; Stammers, DK; Stamp, A; Weaver, KL	1
Cao, Y; De Clercq, E; Liu, X; Pannecouque, C; Wang, Y; Zhan, P	1
Angeli, L; Armand-Ugon, M; Botta, M; Contemori, L; Esté, JA; Franchi, L; Gonzalez, E; Llano, A; Maga, G; Radi, M; Samuele, A; Zanoli, S	1
Armanasco, N; Azijn, H; de Bethune, MP; Fletcher, P; Harman, S; Manlow, P; Nuttall, J; Perumal, D; Romano, J; Shattock, R	1
Chou, KC; González-Díaz, H; Martinez de la Vega, O; Prado-Prado, FJ; Ubeira, FM; Uriarte, E	1
Alongi, M; Angeli, L; Armand-Ugon, M; Baltzinger, M; Bec, G; Bellucci, L; Botta, M; Casaluce, G; Dumas, P; Ennifar, E; Esté, JA; Giorgi, G; Gonzalez, E; Maga, G; Radi, M; Samuele, A; Tafi, A; Zanoli, S	1
Bergamini, A; Borrelli, G; Brindisi, M; Butini, S; Campiani, G; Coccone, SS; Cosconati, S; Di Mattia, M; Galletti, B; Gemma, S; Giorgi, G; Lalli, S; Maga, G; Marinelli, L; Novellino, E; Ramunno, A; Samuele, A; Zanoli, S	1
Bachmann, MH; Fessel, WJ; Kagan, RM; Mitsuya, Y; Shafer, RW; Shahriar, R; Varghese, V	1
Balzarini, J; Brancale, A; Cirilli, R; Coluccia, A; Giordano, C; La Regina, G; La Torre, F; Lavecchia, A; Maga, G; Novellino, E; Piscitelli, F; Samuele, A; Sansone, A; Silvestri, R; Zanoli, S	1
DiStefano, DJ; Hazuda, DJ; Lai, MT; McKenna, PM; Miller, MD; Munshi, V; Touch, S; Tucker, TJ; Tynebor, RM; Williams, TM	1
Boland, S; Cauvin, C; de Walque, S; Demonté, D; Durant, F; Georges, B; Hevesi, L; Le Van, K; Martinelli, V; Van Lint, C	1
Chimirri, A; Clercq, ED; De Luca, L; Ferro, S; Iraci, N; Logoteta, P; Maga, G; Monforte, AM; Pannecouque, C	1
De Clercq, E; Fang, Z; Li, Z; Liu, X; Pannecouque, C; Zhan, P	1
Clercq, ED; Fang, Z; Li, Z; Liu, X; Pannecouque, C; Zhan, P; Zhu, J	1
Andries, K; Benjahad, A; de Béthune, MP; Decrane, L; Grierson, DS; Guillemont, J; Hertogs, K; Nguyen, CH; Oumouch, S; Palandjian, P; Queguiner, L; Vernier, D	1
Bar-Magen, T; Brenner, BG; Oliveira, M; Quan, Y; Schader, SM; Wainberg, MA; Xu, H	1
Carta, A; Fermeglia, M; La Colla, P; Loddo, R; Piras, S; Pricl, S	1
Azijn, H; Boven, K; de Béthune, MP; Jochmans, D; Kraus, G; Picchio, G; Rimsky, LT; Tirry, I; Van Craenenbroeck, E; Vingerhoets, J	1
Akonde, A; Calvez, V; Cisse, M; Costagliola, D; Derache, A; Descamps, D; Diarra, B; Katlama, C; Koita, V; Maïga, AI; Malet, I; Marcelin, AG; Masquelier, B; Morand-Joubert, L; Tounkara, A; Verlinden, Y; Wirden, M	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chimirri, A; De Clercq, E; De Luca, L; Ferro, S; Iraci, N; Logoteta, P; Maga, G; Monforte, AM; Pannecouque, C	1
Gatanaga, H; Hachiya, A; Hayashida, T; Ode, H; Oka, S; Sato, H	1
Fransen, S; Gupta, S; Huang, W; Paxinos, EE; Petropoulos, CJ; Stawiski, E	1
Anderson, KS; Bollini, M; Domaoal, RA; Jorgensen, WL; Leung, CS; Spasov, KA; Thakur, VV; Zeevaart, JG	1
Balzarini, J; Chen, FE; De Clercq, E; Feng, XQ; Liang, YH; Pannecouque, C; Zeng, ZS	1
Bar-Magen, T; Oliveira, M; Quan, Y; Schader, SM; Wainberg, MA; Xu, HT	1
Balzarini, J; Chen, FE; Clercq, ED; Feng, XQ; He, QQ; Liang, YH; Liu, ZQ; Pannecouque, C; Zeng, ZS	1
Balzarini, J; Chen, FE; De Clercq, E; Feng, XQ; He, QQ; Liang, YH; Pannecouque, C; Zeng, ZS	1
Corbau, R; Fishburn, L; Irving, S; Knöchel, T; Martin, A; Mori, J; Mowbray, C; Panton, W; Perros, M; Phillips, C; Ringrose, H; Smith-Burchnell, C; Thornberry, A; Westby, M; Wood, A	1
Bukhtiyarova, M; Chao, W; Dorsey, BD; Joseph, RW; Lee, Y; Liu, B; Michelotti, EL; Petrassi, HM; Springman, EB; Zou, J	1
Engelman, A; Haim, H; Koh, Y	1
Haefeli, WE; Weiss, J; Zembruski, NC	1
Balzarini, J; Brancale, A; Coluccia, A; Gatti, V; La Regina, G; Maga, G; Novellino, E; Pannecouque, C; Piscitelli, F; Samuele, A; Schols, D; Silvestri, R	1
Artico, M; Clotet, B; Esté, JA; Gonzalez-Ortega, E; Maga, G; Mai, A; Nawrozkij, MB; Rotili, D; Samuele, A; Tarantino, D	1
De Clercq, E; Ge, W; Jiang, Y; Li, Z; Liu, X; Pannecouque, C; Wu, J; Zhan, P; Zhang, J	1
Bartolini, S; Castellano, S; Cirilli, R; Lavia, P; Mai, A; Milite, C; Orlando, S; Rotili, D; Santoriello, M; Sbardella, G; Sciamanna, I; Serafino, A; Spadafora, C	1
Balzarini, J; Chen, FE; De Clercq, E; Gu, SX; He, QQ; Ma, XD; Pannecouque, C; Yang, SQ	1
Chen, W; Chen, X; De Clercq, E; Li, D; Li, X; Liu, X; Pannecouque, C; Tian, Y; Zhan, P	1
Balzarini, J; Gurskaya, GV; Ivanov, AV; Ivanova, ON; Kochetkov, SN; Novikov, MS; Ozerov, AA; Pannecouque, C; Seley-Radtke, KL; Temburnikar, K; Valuev-Elliston, VT	1
Balzarini, J; Chen, FE; Clercq, ED; Dai, HF; Gu, SX; He, QQ; Ma, XD; Pannecouque, C; Yang, SQ	1
Anderson, KS; Bollini, M; Domaoal, RA; Gallardo-Macias, R; Jorgensen, WL; Spasov, KA; Thakur, VV	1
Balzarini, J; Chen, X; De Clercq, E; Liu, X; Pannecouque, C; Zhan, P	1
Artico, M; Ballante, F; Botta, G; Cirilli, R; Clotet, B; Esté, JA; Gonzalez, E; Maga, G; Mai, A; Morera, L; Musmuca, I; Nawrozkij, MB; Pierini, M; Ragno, R; Rotili, D; Samuele, A; Tarantino, D	1
Balzarini, J; Chen, FE; De Clercq, E; Gu, SX; He, QQ; Li, ZM; Ma, XD; Pannecouque, C; Yang, SQ	1
Chen, X; Cheng, Z; De Clercq, E; Liu, X; Meng, C; Pannecouque, C; Shao, S; Zhan, P	1
Borrell, JI; Clotet, B; Esté, JA; Giménez, L; Gonzalo, E; Pascual, R; Pettersson, S; Puig-de-la-Bellacasa, R; Teixidó, J	1
Brancale, A; Clotet, B; Coluccia, A; Cosconati, S; Esté, JA; Famiglini, V; Gonzalez, E; La Regina, G; Maga, G; Novellino, E; Piscitelli, F; Samuele, A; Schols, D; Silvestri, R	1
Balzarini, J; Chen, X; De Clercq, E; Li, D; Li, X; Liu, H; Liu, X; Pannecouque, C; Wang, L; Zhan, P	1
Chen, W; Chen, X; De Clercq, E; Li, X; Li, Z; Liu, X; Pannecouque, C; Tian, Y; Zhan, P	1
Chen, W; Chen, X; Clercq, ED; Li, X; Li, Z; Liu, X; Pannecouque, C; Tian, Y; Zhan, P	1
Anderson, KS; Bollini, M; Gallardo-Macias, R; Jorgensen, WL; Spasov, KA; Tirado-Rives, J	1
Andrei, G; Babkov, DA; Balzarini, J; Gavryushov, SA; Ivanov, AV; Khandazhinskaya, AL; Kochetkov, SN; Novikov, MS; Pannecouque, C; Paramonova, MP; Seley-Radtke, KL; Snoeck, R; Valuev-Elliston, VT	1
Cannizzaro, C; Chen, X; Desai, MC; Lansdon, EB; Parrish, J; Tong, L; Wang, M; Xu, L; Zheng, X	1
Balzarini, J; De Clercq, E; Li, D; Liu, H; Liu, X; Pannecouque, C; Zhan, P	1
Chen, FE; Daelemans, D; De Clercq, E; Liu, Y; Ma, XD; Pannecouque, C; Yang, S	1
Anderson, KS; Arnold, E; Bauman, JD; Bollini, M; Cisneros, JA; Das, K; Frey, KM; Jorgensen, WL; Spasov, KA	1
Anderson, KS; Bollini, M; Cisneros, JA; Jorgensen, WL; Spasov, KA	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Balzarini, J; Chen, FE; Chen, WX; Daelemans, D; De Clercq, E; He, QQ; Pannecouque, C; Wu, HQ; Yan, ZH	1
Balzarini, J; Chen, W; Chen, X; De Clercq, E; Liu, X; Pannecouque, C; Rai, D; Tian, Y; Zhan, P	1
Balzarini, J; Chen, X; De Clercq, E; Liu, H; Liu, X; Meng, Q; Pannecouque, C; Wang, D	1
Balzarini, J; Chen, X; De Clercq, E; Li, Z; Liu, H; Liu, X; Pannecouque, C; Xie, Z; Zhan, P; Zhang, L; Zhao, T	1
Ba, M; Gu, Q; Guo, Y; Li, D; Li, G; Li, L; Ma, X; Zhu, T	1
Balzarini, J; Chimirri, A; De Luca, L; Ferro, S; Lo Surdo, G; Monforte, AM; Morreale, F; Pannecouque, C	1
De Clercq, E; Li, Z; Liu, H; Liu, X; Pannecouque, C; Wang, J; Zhan, P	1
Chen, FE; Chen, WX; De Clercq, E; He, QQ; Huang, XY; Pannecouque, C; Wu, HQ; Yan, ZH	1
Badia, R; Brancale, A; Cirilli, R; Clotet, B; Coluccia, A; Crespan, E; Esté, JA; Famiglini, V; La Regina, G; Maga, G; Novellino, E; Pelliccia, S; Silvestri, R	1
Chen, FE; Chen, WX; De Clercq, E; He, QQ; Pannecouque, C; Piao, HR; Wu, HQ; Wu, Y; Yan, ZH	1
Collu, G; Giliberti, G; La Colla, P; Loddo, R; Loksha, YM; Pedersen, EB; Sanna, G	1
Babushkin, AS; Badia, R; Ballante, F; Botta, G; Cirilli, R; Crespan, E; Esté, JA; Maga, G; Mai, A; Marrocco, B; Menta, S; Nawrozkij, MB; Ragno, R; Rotili, D; Tarantino, D	1
Balzarini, J; Chen, F; Chen, W; De Clercq, E; Liu, Y; Meng, G; Pannecouque, C; Zheng, A	1
Ba, M; Cao, Y; Guo, C; Guo, Y; He, R; Li, Z; Liang, Y; Tang, C; Xu, Z; Yang, Y; Zhang, X; Zhou, H; Zhu, L	1
Balzarini, J; Chen, W; De Clercq, E; Li, X; Liu, H; Liu, X; Lu, X; Pannecouque, C; Zhan, P	1
Ariën, KK; Augustyns, K; Cos, P; Dirié, B; Heeres, J; Joossens, J; Lewi, PJ; Lyssens, S; Maes, L; Michiels, J; Van der Veken, P; Vanham, G; Venkatraj, M	1
Chen, W; De Clercq, E; Liu, X; Liu, Z; Pannecouque, C; Zhan, P	1
Anderson, KS; Bollini, M; Frey, KM; Gallardo-Macias, R; Jorgensen, WL; Lee, WG; Spasov, KA	1
Agostino, B; Badia, R; Botta, M; Brancale, A; Cirilli, R; Coluccia, A; Crespan, E; Esté, JA; Famiglini, V; Ferretti, R; La Regina, G; Limongelli, V; Maga, G; Novellino, E; Pelliccia, S; Riveira-Muñoz, E; Schols, D; Silvestri, R; Zamperini, C	1
Chen, FE; Chen, WX; Daelemans, D; De Clercq, E; He, QQ; Pannecouque, C; Wu, HQ; Yao, J	1
Balzarini, J; Chen, W; De Clercq, E; Fu, L; Huang, B; Li, C; Liu, H; Liu, T; Liu, X; Pannecouque, C; Sun, Y; Yu, M; Zhan, P	1
Babkov, DA; Balzarini, J; Chizhov, AO; Daelemans, D; Ivanov, AV; Khandazhinskaya, AL; Kochetkov, SN; Novikov, MS; Ozerov, AA; Pannecouque, C; Paramonova, MP; Seley-Radtke, KL; Valuev-Elliston, VT	1
Chen, W; De Clercq, E; Fu, L; Huang, B; Li, C; Li, X; Liang, X; Liu, H; Liu, T; Liu, X; Pannecouque, C; Sun, Y; Zhan, P	1
Chen, FE; Chen, WX; Daelemans, D; De Clercq, E; He, QQ; Mao, TQ; Pannecouque, C; Tang, GF; Wan, ZY	1
Chen, FE; Daelemans, D; De Clercq, E; Lu, YP; Mao, TQ; Pannecouque, C; Tao, Y; Wan, ZY; Wang, HF; Wang, XL; Wu, Y; Yao, J; Yin, H	1
Chen, FE; Daelemans, D; De Clercq, E; Mao, TQ; Pannecouque, C; Piao, HR; Tao, Y; Wan, ZY; Wang, YF; Yin, H	1
Chen, FE; Chen, WX; Daelemans, D; De Clercq, E; Mao, TQ; Pannecouque, C; Wan, ZY; Wang, HF; Wang, XL; Yao, J; Yin, H	1
Balzarini, J; De Clercq, E; Gu, SX; Ju, XL; Liu, H; Pannecouque, C; Qiao, H; Shu, QC; Zhu, YY	1
Chen, W; Daelemans, D; De Clercq, E; Huang, B; Kang, D; Li, X; Liu, X; Liu, Z; Lu, X; Pannecouque, C; Yang, J; Zhan, P	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Chen, X; Daelemans, D; De Clercq, E; Huang, B; Kang, D; Li, W; Liu, X; Meng, Q; Pannecouque, C; Zhan, P	1
Chizhov, AO; Geisman, AN; Khandazhinskaya, AL; Kochetkov, SN; Naesens, L; Novikov, MS; Ozerov, AA; Pannecouque, C; Seley-Radtke, KL; Valuev-Elliston, VT	1
Buckheit, RW; Cushman, M; Hartman, TL; Hoshi, A; Okazaki, M; Pannecouque, C; Sakamoto, T; Takayama, J; Xuan, M	1
Chen, W; Daelemans, D; De Clercq, E; Huang, B; Liu, X; Pannecouque, C; Yang, J; Zhan, P	1
Elgaher, WA; Hartmann, RW; Haupenthal, J; Mély, Y; Pires, M; Real, E; Saladini, F; Sharma, KK	1
Detorio, M; Domaoal, RA; Ehteshami, M; Feraud, M; Hammond, ET; Lu, X; Montero, C; Nettles, JH; Schinazi, RF; Stanton, RA	1
Ba, M; Cao, Y; Guo, C; Guo, J; Guo, Y; He, R; Huang, X; Li, X; Li, Z; Xu, Z; Yang, Y; Yu, M; Zhang, M; Zhou, H	1
Jorgensen, WL	1
Daelemans, D; De Clercq, E; Huang, B; Kang, D; Li, X; Liu, X; Lu, X; Pannecouque, C; Yang, J; Zhan, P; Zhao, F; Zhou, Z	1
Daelemans, D; De Clercq, E; Ding, X; Fang, Z; Huang, B; Kang, D; Li, Z; Liu, X; Lu, X; Pannecouque, C; Xu, H; Zhan, P; Zhang, H; Zhou, Z	1
De Clercq, E; Huo, Z; Kang, D; Liu, H; Liu, X; Pannecouque, C; Tian, Y; Zhan, P; Zhang, H; Zhou, Z	1
Gu, SX; Ju, XL; Li, TT; Lu, HH; Pannecouque, C; Xiao, T; Xue, P; Zhang, X; Zheng, XJ; Zhu, YY	1
Gu, SX; Ju, XL; Liu, GY; Lu, HH; Pannecouque, C; Xue, P; Zhang, XL; Zheng, XJ; Zhu, YY	1
Daelemans, D; De Clercq, E; Ding, X; Fang, Z; Huang, B; Huo, Z; Kang, D; Liu, X; Lu, X; Meng, Q; Pannecouque, C; Tian, Y; Wu, G; Xu, H; Yu, Z; Zhan, P; Zhang, H; Zhou, Z	1
Agharbaoui, FE; Buemi, MR; De Luca, L; Ferro, S; Monforte, AM; Pannecouque, C	2
Badia, R; Brambilla, A; Brancale, A; Catalano, M; Cirilli, R; Coluccia, A; Crespan, E; Esté, JA; Famiglini, V; Formica, FR; La Regina, G; Limatola, C; Maga, G; Masci, D; Novellino, E; Riveira-Muñoz, E; Silvestri, R	1
Daelemans, D; De Clercq, E; Huang, B; Kang, D; Liu, J; Liu, X; Liu, Z; Pannecouque, C; Tian, Y; Zhan, P	1
Chen, F; De Clercq, E; Jin, K; Meng, G; Pannecouque, C; Yin, H	1
Daelemans, D; De Clercq, E; Huang, B; Kang, D; Liu, X; Pannecouque, C; Tian, Y; Zhan, P; Zhou, Z	1
Daelemans, D; De Clercq, E; Gao, P; Kang, D; Liu, X; Lu, X; Pannecouque, C; Yang, J; Zhan, P	1
Chen, CH; Daelemans, D; De Clercq, E; Huang, B; Kang, D; Lee, KH; Liu, J; Liu, X; Liu, Z; Pannecouque, C; Tian, Y; Zhan, P; Zhang, H	1
Daelemans, D; De Clercq, E; Desta, S; Ding, X; Huo, Z; Jing, L; Kang, D; Liu, X; Pannecouque, C; Wang, Z; Wu, G; Zhan, P; Zhang, H; Zhou, Z; Zuo, X	1
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De Clercq, E; Jin, K; Meng, G; Pannecouque, C; Sang, Y	1
Byrareddy, SN; Kongsted, J; Kramer, VG; Kurup, S; Liu, X; Namasivayam, V; Vanangamudi, M; Zhan, P	1
Armijos Rivera, JI; Badia, R; Cirilli, R; Crespan, E; Esté, JA; Forgione, M; Hailu, GS; Kirillov, IA; Lucidi, A; Maga, G; Mai, A; Nawrozkij, MB; Panella, C; Patsilinakos, A; Ragno, R; Riveira-Muñoz, E; Rotili, D; Tomaselli, D; Yablokov, AS	1
Daelemans, D; De Clercq, E; Kang, D; Liu, X; Pannecouque, C; Tian, Y; Wang, Z; Yu, Z; Zhan, P; Zhang, J	1
Chen, F; De Clercq, E; Han, S; Jin, K; Meng, G; Pannecouque, C; Sang, Y	1
Chen, F; De Clercq, E; Han, S; Pannecouque, C; Sang, Y; Zhuang, C	2
Chen, FE; De Clercq, E; Han, S; Pannecouque, C; Sang, Y; Tao, Y; Wu, Y; Zhuang, C	1
Chen, FE; Gu, SX; Liu, GY; Meng, G; Pannecouque, C; Tang, JF; Wu, FS; Xiao, T; Xu, ZQ; Zhu, YY	1
Cen, S; Dong, B; Guo, Y; Liang, C; Ma, L; Wang, J; Wang, Y; Wang, Z; Wen, J; Zhang, G; Zhou, J; Zhu, M	1
Arnold, E; De Clercq, E; Fang, Z; Feng, D; Kang, D; Liu, X; Pannecouque, C; Pilch, A; Ruiz, FX; Sun, Y; Wang, Z; Wei, F; Zhan, P; Zhao, T	1
De Clercq, E; Feng, D; Jiang, X; Jing, L; Kang, D; Liu, X; Pannecouque, C; Sun, Y; Wei, F; Wu, G; Zhan, P	1
Chen, FE; Chen, X; De Clercq, E; Ding, L; Pannecouque, C; Tao, Y; Zhuang, C	1
Armijos Rivera, JI; Badia, R; Brambilla, A; Catalano, M; Cinquina, E; Coluccia, A; Crespan, E; Esté, JA; Falasca, F; La Regina, G; Limatola, C; Maga, G; Masci, D; Nalli, M; Riveira-Muñoz, E; Silvestri, R; Turriziani, O	1
Cherukupalli, S; De Clercq, E; Feng, D; Fu, Z; Jiang, X; Kang, D; Liu, X; Pannecouque, C; Wang, Z; Zhan, P	1
De Clercq, E; Huang, B; Jiang, X; Kang, D; Li, J; Liu, X; Olotu, FA; Pannecouque, C; Soliman, MES; Wang, Z; Zhan, P	1
Chen, CH; De Clercq, E; Feng, D; Jing, L; Kang, D; Lee, KH; Lin, H; Liu, X; Olotu, FA; Pannecouque, C; Soliman, M; Zhan, P; Zuo, X	1
Chen, FE; De Clercq, E; Ding, L; Pannecouque, C; Zhuang, C	3
De Clercq, E; Gao, P; Liu, X; Pannecouque, C; Song, S; Sun, L; Wang, Z; Zhan, P; Zhang, J	1
Cherukupalli, S; De Clercq, E; Fu, Z; Gao, S; Kang, D; Liu, X; Pannecouque, C; Sun, L; Zhan, P; Zhang, T; Zhou, Z	1
Chen, FE; De Clercq, E; Jin, X; Pannecouque, C; Piao, HR; Zhuang, C	1
Cherukupalli, S; De Clercq, E; Jia, R; Jiang, X; Kang, D; Liu, X; Pannecouque, C; Wang, W; Wang, Z; Xie, M; Zhan, P	1
Cheng, Y; De Clercq, E; Gao, P; Gao, S; Kang, D; Liu, X; Pannecouque, C; Song, L; Song, S; Sun, L; Xu, S; Zhan, P; Zhao, F	1
Chen, FE; De Clercq, E; Huang, WJ; Jin, X; Pannecouque, C; Wang, S; Zhang, YX; Zhao, LM	1
Chen, FE; Clercq, E; Hao, QQ; Ling, X; Pannecouque, C	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
De Clercq, E	1
Saag, MS; Schooley, RT	1
Gatell, JM; Martínez, E	1
Crowe, S	1
Temesgen, Z; Wright, AJ	1
Clotet, B	1
Arnó, A; Blazquez, J; Bloor, S; Bonjoch, A; Casado, JL; Clotet, B; Dronda, F; Garcia-Arata, I; Hertogs, K; Larder, B; Ruiz, L; Van Cauwenberge, A	1
Consiglio, E; Ferrer, E; Gudiol, F; Podzamczer, D	1
Balzarini, J; Burt, V; Carbonez, A; De Clercq, E; Kleim, JP	1
Barreiro, P; Briones, C; Dona, C; González-Lahoz, J; Soriano, V	1
Blayac, JP; Faucherre, V; Peyriere, H; Pinzani, V	1
Cheesbrough, A; Gazzard, BG; Leen, C; Moyle, GJ; Reynolds, B; Wilkins, E	1
Baldwin, C; Moyle, G	1
Eap, CB	1
Barreiro, P; Dona, C; González-Lahoz, J; Soriano, V	1
Bower, M; Gazzard, BG; Mandalia, S; Matthews, GV; Moyle, GJ; Nelson, M	1
Barry, M; Clarke, S; Harrington, P; Mulcahy, F	1
Milton, J; Ren, J; Short, SA; Stammers, DK; Stuart, DI; Weaver, KL	1
Moyle, G	1
Daily, JP; Duan, SX; Giancarlo, GM; Granda, BW; Greenblatt, DJ; Harmatz, JS; Shader, RI; von Moltke, LL	1
Gosselin, G; Hübscher, U; Maga, G; Pregnolato, M; Spadari, S; Ubiali, D	1
Deeks, SG	1
Soriano, V	1
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Cadman, J	1
Fornataro, K	2
Chiodo, F; Manfredi, R	1
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Adachi, A; Fujiwara, T; Hayami, M; Isaka, Y; Kawauchi, S; Miki, S; Miura, T; Sato, A; Sugimoto, H; Suyama, A; Yoshie, O	1
Bartoli, A; Feroggio, M; Gianelli, L; Maserati, R; Montagna, M; Regazzi, MB; Villani, P	1
Chou, TC; Giguel, F; Hirsch, MS; Kollmann, C; Tremblay, C	1
Nelson, M	1
Arribas, J	1
Maggiolo, F	1
Lafeuillade, A	1
Stellbrink, HJ	1
Agher, R; Calvez, V; Delaugerre, C; Huraux, JM; Katlama, C; Mouroux, M; Rohban, R; Simon, A; Tricot, C	1
DiCenzo, R; Morse, GD; Smith, PF	1
Bower, M; Gazzard, BG; Johnson, MA; Lampe, F; Mandalia, S; Matthews, GV; Nelson, MR; Phillips, AN; Sabin, CA	1
Chaisson, RE; Mehta, SH; Moore, RD; Sulkowski, MS; Thomas, DL	1
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Olivieri, J	1
de Groot, R; Fraaij, PL; van Rossum, AM	1
Arendt, G; Köller, H; Theisen, A; von Giesen, HJ	1
Abrescia, N; Cozzi-Lepri, A; d'Arminio Monforte, A; Leoncini, F; Moroni, M; Orani, A; Petrosillo, N; Phillips, AN; Piersantelli, N; Scerbo, A; Tundo, P	1
Campiani, G; Catalanotti, B; Fattorusso, C; Maga, G; Morelli, E; Nacci, V; Novellino, E; Ramunno, A	1
Airoldi, M; Carosi, G; Casari, S; Castelli, F; Fausti, C; Moretti, F; Pan, A; Quiros-Roldan, E; Torti, C	1
Erickson-Viitanen, SK; King, RW; Klabe, RM; Reid, CD	1
Edno-Mcheik, L; Lagrange, F; Molimard, M; Moore, N; Péhourcq, F; Titier, K	1
Kashuba, AD; Rezk, NL; Tidwell, RR	1
Brenner, B; Detorio, M; Loemba, H; Ma'ayan, S; Moisi, D; Oliveira, M; Parniak, MA; Spira, B; Wainberg, MA	1
Casado, JL; Dronda, F; Hertogs, K; Moreno, A; Moreno, S	1
Greenblatt, DJ; Perloff, MD; Störmer, E; von Moltke, LL	1
Flexner, C; Gandhi, R	1
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Bahar, I; Temiz, NA	1
Aarnoutse, RE; Burger, DM; Droste, JA; Hekster, YA; Koopmans, PP	1
Bell, C; Matthews, GV; Nelson, MR	1
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Oka, S; Teruya, K	1
Pulido, F; Torralba, M	1
Carro, JA; Cuevas, MJ; Martín, V; Mostaza, JL; Ortega, L; Pérez-Simón, MR	1
Calvez, V; Delaugerre, C; Herson, S; Katlama, C; Legrand, M; Marcelin, AG; Paris, L; Peytavin, G; Schneider, L; Simon, A; Tubiana, R; Wirden, M	1
Antela, A; Casado, JL; Dronda, F; Gutiérrez, C; Moreno, A; Moreno, S; Pérez-Elías, MJ	1
Dieterich, DT; Kontorinis, N	1
Burns, DJ; Chen, CM; David, CA; Lim, B; Middleton, TR; Pithawalla, R; Tripathi, RL; Warrior, U; Xuei, X	1
Beijnen, JH; Huitema, AD; Kappelhoff, BS; Rosing, H	1
Moyle, GJ	2
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Bossi, P; Bricaire, F; Caumes, E; Katlama, C	1
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Boyd, MA; Cooper, DA; Dore, GJ; Duncombe, CJ; Lange, JM; Law, WP; Mahanontharit, A; Phanuphak, P; Ruxrungtham, K	1
Boyle, BA	2
Fowler, MG; Greenberg, AE; Holmberg, S; Moorman, A; Tong, TC	1
Amador, C; Benito, C; Ena, J; Fenoll, V; Pasquau, F	1
Hirschel, B	1
de la Rosa, R; Heath, KV; Hogg, RS; Lee, N; Montaner, JS; O'Shaughnessy, MV; Wood, E; Yip, B	1
Carroll, H; Conlon, V; Green, A; Green, DC; Green, R; Jefferson, R; Jordan, WC; Tolbert, L; Yemofio, F	1
Manosuthi, W; Rattanasiri, S; Sungkanuparph, S; Thakkinstian, A; Vibhagool, A	1
Arranz-Caso, JA; Estrada, V; García-Diaz, JD; Gorgolas, M	1
Calza, L; Chiodo, F; Manfredi, R	2
Averbuch, D; Bar Yaacov, N; Burke, M; Chowers, M; Grossman, Z; Istomin, V; Levi, I; Lorber, M; Risenberg, K; Schapiro, JM	1
Back, D; Fletcher, C; Gazzard, B; Gibbons, S; Mandalia, S; Nelson, M; Parmar, D; Pozniak, A; Smith, N; Winston, A	1
Carr, A	1
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Bouvet, E; Descamps, D; Larouzé, B; Massari, V; Parienti, JJ; Vabret, A; Verdon, R	1
Bower, M; Gazzard, B; Jones, R; Mandalia, S; Michailidis, C; Nelson, M; Sawleshwarkar, S; Stebbing, J; Waters, L	1
Meyer-Kleinmann, J	1
Bordenave, B; Claxton, S; Henry, K; Kane, E; Klebert, M; Powderly, WG; Tebas, P; Yarasheski, K	1
Hamatake, R; Hong, Z; Zhang, Z	1
Chiesi, A; Fisher, M; Horban, A; Kirk, O; Ledergerber, B; Lundgren, JD; Machala, L; Mulchany, F; Phillips, AN; Reiss, P	1
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Conway, B; Fisher, M; Jelaska, A; Lange, JM; Laplumé, H; Martin, D; van Leth, F; Wit, FW	1
Xie, L; Zhou, T	1
Corral, A; Gallego, O; González de Requena, D; Jiménez-Nácher, I; Soriano, V	1
Clavel, F; Hance, AJ; Joly, V; Lecossier, D; Morand-Joubert, L; Shafer, RW; Shulman, NS; Zolopa, AR	1
Gerber, JG; Wyles, DL	1
Goff, SP; Moore, KL; Sluis-Cremer, N; Tachedjian, G	1
Boeri, E; Castagna, A; Gallotta, G; Gianotti, N; Maillard, M; Ratti, D; Serra, G; Tremolada, Y; Vacchini, D	1
Ananworanich, J; Cardiello, P; Chan, J; Cooper, DA; Duncombe, C; Lange, J; Moor, Z; Phanuphak, P; Ruxrungtham, K; Siangphoe, U	1
Blanco, JL; Gatell, JM; Laguno, M; León, A; Mallolas, J; Martinez, E; Pumarola, T	1
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Friedland, G	1
Brust, J; Hartmann, M; Klinker, H; Mosthaf, F; Petzoldt, D; Procaccianti, M; Rump, JA; Schuster, D	1
Badaro, R; de Wet, J; Hall, DB; Huisamen, CB; Lange, JM; Montaner, JS; van Leth, F; Vandercam, B; Wit, FW	1
Andréola, M; Cruchaga, C; Martínez-Irujo, JJ; Odriozola, L; Tarrago-Litvak, L	1
Beijnen, JH; Huitema, AD; Kappelhoff, BS; Lange, J; MacGregor, TR; van Leth, F	1
Andrews, S; Grinsztejn, B; Lange, JM; Lazanas, MK; Montaner, J; van Leth, F; Wilkins, E	1
Mallal, S; Nolan, D; Reiss, P	1
Jaillon, P; Poirier, JM; Robidou, P	1
Lee, J	1
Biollaz, J; Bleiber, G; Buclin, T; Colombo, S; Décosterd, L; Furrer, H; Keiser, O; Lee, BL; Rotger, M; Telenti, A	1
Heseltine, PN; Kagan, RM; Kovari, L; Merigan, TC; Winters, MA	1
Balzarini, J; Gago, F; Rodríguez-Barrios, F	1
Crespo, M; Ferrer, E; Fisac, C; Fumero, E; Gatell, JM; Podzamczer, D; Ribera, E; Roson, B; Virgili, N	1
Akarathum, N; Kanjanavanit, S; Oberdorfer, A; Puthanakit, T; Sirisanthana, T; Sirisanthana, V; Wannarit, P	1
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Calza, L; Chiodo, F; Colangeli, V; Manfredi, R; Pocaterra, D; Sebastiani, T; Tampellini, L	1
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Brust, J; Hartmann, M; Klinker, H; Mosthaf, F; Petzoldt, D; Procaccianti, M; Rump, JA; Schuster, D; Witte, S	1
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Arendt, V; Fundira, L; Lemmer, P; Omes, C; Schneider, S; Schuman, M; Tayari, JC; Wennig, R	1
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Kabra, SK; Lodha, R; Upadhyay, A	1
Huang, MH; Wu, L; Yang, MS; Zhao, JL	1
Billaud, E; Bugnon, F; Cua, E; Cuzin, L; Dellamonica, P; Delpierre, C; Massip, P; Pugliese, P; Raffi, F	1
Nolan, D	1
Burger, DM; Droste, JA; Hekster, YA; Kearney, BP	1
Baker, A; Crawford, W; Jassen, A; Jooste, JP; Van Zyl, AJ	1
Black, FT; Jørgensen, LB; Kjems, J; Mohey, R; Møller, BK; Obel, N; Tolstrup, M	1
Beijnen, JH; Boron-Kaczmarska, A; Hall, DB; Huitema, AD; Johnson, D; Kappelhoff, BS; Lange, JM; Leith, J; Leth, FV; Livrozet, JM; Losso, MH; Saag, MS; Wit, FW	1
Eshleman, SH; Galovich, J; Jackson, JB; Jones, D; Parkin, N; Paxinos, EE; Petropoulos, CJ	1
Bosch, RJ; Clark, SA; Mellors, JW; Shulman, NS	1
Danielson, UH; Geitmann, M; Unge, T	1
Talbot, M	2
Amin, J; Cooper, DA; Emery, S; Hales, G; Winston, A	1
Bourdet, DL; Brouwer, KL; Ho, RH; Kashuba, AD; Kim, RB; Leake, BF; Lowe, CM; McRae, MP; Tian, X	1
Arvieux, C; Dailly, E; Jolliet, P; Perré, P; Raffi, F; Tattevin, P; Tribut, O	1
Curtin, JM; Ward, DJ	1
Hall, DB; Lange, JM; Reiss, P; van Leth, F	1
Chumpathat, N; Manosuthi, W; Muangchana, K; Sungkanuparph, S; Thongyen, S	1
Donahue, JP; Erdem, H; George, AL; Haas, DW; Haines, JL; Kim, RB; Motsinger, AA; Raffanti, S; Rebeiro, P; Ritchie, MD; Sterling, TR	1
Lange, JM; van Leth, F	1
Faucette, SR; LeCluyse, EL; Moore, R; Negishi, M; Omiecinski, CJ; Sueyoshi, T; Wang, H; Zhang, TC	1
Abgrall, S; Bouchaud, O; Costagliola, D; Yeni, PG	2
Balfour, HH; Brundage, RC; Vezina, HE; Weller, DR	1
Calza, L; Manfredi, R	1
de Bethune, MP; Figueiredo, A; Mak, J; Moore, KL; Sluis-Cremer, N; Tachedjian, G	1
Ditangco, R; Kamarulzaman, A; Kiertiburanakul, S; Phanupak, P; Pujary, S; Zhou, J	1
Clax, PA; Cohn, SE; Hitti, J; Lertora, JJ; Park, JG; Stek, A; Watts, DH; Yu, S	1
Deadman, J; Garner, J; Griffith, R; Keller, PA; Rhodes, D	1
Choi, SO; Kashuba, AD; Rezk, NL	1
Dahri, K; Ensom, MH	1
Mira, JA; Pineda, JA; Rivero, A	1
Arnaiz, JA; Dalmau, D; de Lazzari, E; Domingo, P; Force, L; Gatell, JM; Knobel, H; Leyes, M; Martínez, E; Pedrol, E; Podzamczer, D; Ribera, E	1
Asiimwe, F; Behumbiize, P; Brooks, JT; Forna, F; Liechty, CA; Mermin, J; Solberg, P; Tong, T; Weidle, PJ; Were, W	1
Barreiro, P; Gonzalez-Lahoz, J; Jiménez-Nácher, I; Labarga, P; Martín-Carbonero, L; Rodríguez-Novoa, S; Ruiz, A; Soriano, V	1
Gupte, N; Patel, AK; Patel, B; Patel, J; Patel, K; Pujari, S; Shah, N	1
Lange, JM; van Leth, F; Wit, FW	1
Arendt, G; de Nocker, D; Nolting, T; von Giesen, HJ	1
Anastos, K; Cohen, M; Cole, S; Hessol, NA; Justman, J; Kaplan, RC; Lu, D; Shi, Q; Tien, PC; Vigen, C; Young, M	1
Ainsworth, JG; Haddow, LJ; Wood, CW	1
Gangakhedkar, RR; Hayatnagarkar, SS; Kurle, SN; Paranjape, RS; Sen, S; Tripathy, SP	1
Bertelsen, L; Jakobsen, MR; Laursen, A; Mohey, R; Obel, N; Ostergaard, L; Tolstrup, M	1
Massari, V; Parienti, JJ; Poubeau, P; Rey, D; Verdon, R	1
Dia Badiane, NM; Diop, BM; Faye, MM; Manga, NM; Ndour, CT; Ngom Gueye, NF; Seydi, M; Soumare, M; Sow, AI; Sow, PS	1
Anderson, KS; Radzio, J; Sluis-Cremer, N; Xia, Q	1
Cecelia, AJ; Devaleenal, B; Flanigan, T; Kumarasamy, N; Mayer, KH; Muthu, S; Palanivel, V; Venkatesh, KK; Yepthomi, T	1
Anitha, S; Hemanth Kumar, AK; Kumar, P; Rajasekaran, S; Ramachandran, G; Swaminathan, S	1
Maartens, G; Mehta, U	1
Barnard, RJ; Felock, P; Hazuda, DJ; Lai, MT; Lu, M; Miller, MD; Munshi, V	1
Antinori, A; Baxter, J; Cauda, R; Clevenbergh, P; Colafigli, M; De Luca, A; Giambenedetto, SD; Perno, CF; Prosperi, M; Ruiz, L; Trotta, MP	1
Aweeka, F; Burchett, SK; Capparelli, E; Fenton, T; Kovacs, A; Nachman, S; Saitoh, A; Sarles, E; Spector, SA; Wiznia, A	1
Franklin, AM; Jorgensen, WL; Rader, LH; Smith, KD; Smith, MB; Smith, RH; Taylor, EV; Tirado-Rives, J	1
Alvarez, E; Bellón, JM; Berenguer, J; Castillo, I; Cosín, J; López, JC; Miralles, P; Padilla, B; Resino, S; Sánchez Conde, M	1
Bannister, WP; Clotet, B; Cozzi-Lepri, A; Karlsson, A; Kirk, O; Loveday, C; Lundgren, JD; Mocroft, A; Monforte, Ad; Ruiz, L; Staszewski, S	1
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Clax, PA; Cohn, SE; Hitti, J; Lertora, JJ; Muderspach, L; Park, JG; Stek, A; Watts, DH; Yu, S	1
Aurpibul, L; Lee, B; Mangklabruks, A; Puthanakit, T; Sirisanthana, T; Sirisanthana, V	1
Allavena, C; Biron, C; Dailly, E; Jolliet, P; Raffi, F	1
Alonzi, T; Ascenzi, P; Mancone, C; Narciso, P; Notari, S; Tripodi, M	1
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Doerries, R; Drechsler, H; Gass, A; Hardmeier, M; Kuhle, J; Mehling, M; Ruegg, S	1
Borot, N; Hovnanian, A; Ledger, TN; Lefebvre, A; Lonjou, C; Milpied, B; Vitezica, ZG	1
Bacchetti, P; Grunfeld, C; Heymsfield, S; Kotler, DP; Lee, G; Lewis, CE; Madden, E; Scherzer, R; Shlipak, MG; Tracy, R; Wanke, C	1
Cheng, J; Han, N; Liu, YN; Liu, ZY; Wei, HS; Zhang, FJ; Zhao, HX; Zhao, Y	1
Borkowf, CB; Brooks, JT; Buchacz, K; Downing, R; Kigozi, A; Mermin, J; Moore, D; Ndazima, V; Weidle, PJ; Were, W	1
Chimsuntorn, S; Lueangniyomkul, A; Mankatitham, W; Manosuthi, W; Sungkanuparph, S	1
Burger, DM; Compagnucci, A; Cressey, TR; Gibb, DM; Green, H; Khoo, S; Lallemant, M; Saidi, Y; Treluyer, JM	1
Lankoandé, D; Millogo, A; Sawadogo, AB; Yaméogo, AA; Yaméogo, I	1
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Basseila, GB; Bokilo, AD; Dokekias, AE; Galiba, FO; Malanda, F; Nsitou, MB; Ntsimba, P	1
Chhneang, V; Fernandez, M; Laureillard, D; Moeung, S; Ngeth, C; Piketty, C; Prak, N; Quillet, C; Riel, V; Song, S	1
Chearskul, P; Chearskul, S; Chokephaibulkit, K; Lapphra, K; Phongsamart, W; Prasitsuebsai, W; Vanprapar, N	1
Bain, AM; Busti, AJ; Rahman, AP; Rutherford, WS; White, EA	1
Chuturgoon, AA; Dawood, H; Karamchand, L	1
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Gibbins, S; Kon, O; O'Donoghue, M; Obiorah, I; Sathia, L; Taylor, G; Walsh, J; Winston, A	1
Roca, B	1
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Brück, S; Brust, J; Hartmann, M; Klinker, H; Mosthaf, F; Petzold, D; Procaccianti, M; Rump, JA; Schuster, D; Witte, S	1
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Fochesato, CM; Moreira, J; Rezin, GT; Romão, PR; Scaini, G; Streck, EL	1
Camacho, RJ; Deforche, K; Grossman, Z; Harrigan, PR; Kantor, R; Katzenstein, DA; Shafer, R; Soares, MA; Van Laethem, K; Vandamme, AM	1
Chaisson, RE; Dowdy, DW; Gallant, JE; Hislop, M; Maartens, G; Nachega, JB; Regensberg, L	1
Djoerban, Z; Sumantri, S	1
Billheimer, JT; Fuki, IV; Millar, JS; Rader, DJ; Rothblat, GH; Tohyama, J	1
Boesmans, D; Di Fazio, V; Elens, L; Haufroid, V; Vanbinst, R; Veriter, S; Wallemacq, P	1
Bellido, R; Clotet, B; Darwich, L; Esteve, A; Martinez-Picado, J; Ruiz, L	1
Burgisser, P; Cavassini, M; Giulieri, SG; Günthard, HF; Knoepfel, SA; Metzner, KJ; Rauch, P; Yerly, S	1
George, C; Jayakumar, B; Lal, L; Yesoda, A	1
Hemanth Kumar, AK; Jagan, I; Narendran, G; Padmapriyadarsini, C; Rajasekaran, S; Ramachandran, G; Ramesh, K; Swaminathan, S; Vasantha, M	1
Acosta, EP; Floyd, M; Gebretsadik, T; Haas, DW; Mayo, G; Menon, UN; Shintani, A; Stein, CM; Wilkinson, GR	1
Kulsomboon, V; Maleewong, U; Teerawattananon, Y	1
Kiertiburanakul, S; Malathum, K; Sathapatayavongs, B; Sungkanuparph, S; Watcharananan, S	1
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Fisac, C; Gatell, JM; Martínez, E; Podzamczer, D; Ribera, E; Virgili, N	1
Annan, NT; Bower, M; Gazzard, BG; Mandalia, S; Nelson, M; Stebbing, J	1
Barril, J; Esteban, J; Garcia-Pérez, AG; Giménez, J; Gimeno, C; Mora, E; Pellín, Mde L	1
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Lalloo, UG	1
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Cao, YL; Chen, H; Guo, Y; Li, SX	1
Hanekom, WA; Maartens, G; Meintjes, G; Rangaka, MX; Seldon, R; Wilkinson, KA; Wilkinson, RJ	1
Tozzi, V	1
Back, DJ; Chandler, B; Evans, S; Hartkoorn, R; Janneh, O; Jenkinson, C; Khoo, SH; Kwan, WS; Owen, A	1
Booth, CL; Fox, ZV; Geretti, AM; Heneine, W; Johnson, JA; Johnson, M; Li, JF; Phillips, AN; Smith, CJ	1
Karunaianantham, R; Narayanan, PR; Rajesh, L; Swaminathan, S	1
Kwara, A; Ramachandran, G; Swaminathan, S	1
Asahchop, EL; Brenner, BG; Moisi, D; Ntemgwa, M; Toni, TA; Wainberg, MA	1
Andrade, VM; Boeck, CR; Castro, AA; de Chaves, G; Gavioli, EC; Lemos, JC; Moreira, J; Moretti, M; Quevedo, J; Romão, PR	1
Anta, L; Blanco, JL; de Mendoza, C; García, F; Gutiérrez, F; Leal, M; Pérez-Elías, MJ; Poveda, E; Ribera, E; Soriano, V	1
Battegay, M; Bernasconi, E; Cavassini, M; Elzi, L; Furrer, H; Hirschel, B; Ledergerber, B; Marzolini, C; Vernazza, P; Weber, R	1
Gulick, RM; Kmack, A; Krambrink, A; Kuritzkes, DR; Ribaudo, HJ; Schouten, JT; Shikuma, C; Webb, N	1
de Souza, DF; Diaz, RS; Inocencio, LA; Janini, LM; Munerato, P; Oliveros, MP; Pereira, AA; Sucupira, MC	1
Bartlett, JA; Crump, JA; Cunningham, CK; Emmett, SD; Kinabo, GD; Mmbaga, BT; Reddy, EA; Schimana, W; Swai, ME	1
Deshpande, A; Fleury, HJ; Jeannot, AC; Pinson, P; Schrive, MH; Wittkop, L	1
Asboe, D; Dunn, D; Fearnhill, E; Gazzard, B; Pillay, D; Pozniak, A; Price, H	1
Chassany, O; Costagliola, D; Lavignon, M; Potard, V; Spire, B	1
Dickinson, L; Gibb, DM; Gilks, CF; Kayiwa, J; Khoo, S; Kityo, C; Lutwama, F; Munderi, P; Nalumenya, R; Reid, A; Ssali, F; Tumukunde, D; Walker, AS	1
Coquerel, A; Parienti, JJ; Peytavin, G; Reliquet, V; Verdon, R	1
Andreotti, M; Bucciardini, R; Fragola, V; Galluzzo, C; Giuliano, M; Marchei, E; Palmisano, L; Pellegrini, M; Pichini, S; Pirillo, M; Vella, S; Weimer, L	1
Holmes, SP; Reuman, EC; Rhee, SY; Shafer, RW	1
Butler, DM; Chantratita, W; Manosuthi, W; Richman, DD; Smith, DM; Sukasem, C	1
Beilhartz, GL; Biondi, MJ; Götte, M; McCormick, S	1
Burger, DM; Gelinck, LB	1
Decha, P; Hannongbua, S; Intharathep, P; Parasuk, V; Sompornpisut, P; Udommaneethanakit, T; Wolschann, P	1
Chen, J; Li, L; Lu, H; Ma, Q; Sun, F; Sun, J; Wang, Z; Yao, Y; Zhang, L	1
Fätkenheuer, G; Gatell, J; Katlama, C; Ledergerber, B; Lundgren, JD; Mocroft, A; Parczewski, M; Reekie, J; Reiss, P; Sedlacek, D	1
Bar-Magen, T; Oliveira, M; Quan, Y; Wainberg, MA; Xu, HT	1
Castelnuovo, B; Kamya, MR; Kiragga, A; Manabe, Y	1
Bachani, D; Chan, PL; Deshpande, A; Rajasekaran, S; Rewari, BB; Srikantiah, P	1
Rutherford, GW; Siegfried, N; Spaulding, A	1
Amani-Bosse, C; Anglaret, X; Coffie, PA; Dabis, F; Danel, C; Eholié, SP; Ekouevi, DK; Messou, E; Moh, R; Ouattara, E; Sissoko, M	1
Delaporte, E; Diouf, A; Etard, JF; Girard, PM; Landman, R; Laurent, C; Molinari, N; Ndoye, I; Ngom Guèye, NF; Sow, PS; Tchatchueng Mbougua, JB	1
Domingo, P; Gutierrez, Mdel M; Mateo, MG; Vidal, F	1
Giuliano, M; Marazzi, MC; Nielsen-Saines, K; Palombi, L	1
Irlam, JH; Mbuagbaw, LC; Rutherford, GW; Siegfried, N; Spaulding, A	1
Calvez, V; Flandre, P; Fourati, S; Girard, PM; Haïm-Boukobza, S; Katlama, C; Lavignon, M; Marcelin, AG; Morand-Joubert, L; Sayon, S; Simon, A; Valin, N	1
Burger, DM; de Wolf, F; Franssen, EJ; Kroon, F; Richter, C; Rigter, IM; Smit, C; van Luin, M; Wit, FW	1
Dewar, RL; Dlamini, JN; Follmann, DA; Highbarger, HC; Hu, Z; Pau, AK; Somaroo, H	1
Chirara, M; Crombe, A; Goodall, RL; Gupta, RK; Kaleebu, P; Kityo, C; McCormick, AL; Parry, CM; Pillay, D; Towers, GJ	1
Ariën, KK; Heyndrickx, L; Michiels, J; Quiñones-Mateu, ME; Selhorst, P; Terrazas-Aranda, K; Vanham, G; Vazquez, AC; Vereecken, K; Weber, J	1
Bolhaar, MG; Karstaedt, AS	1
Ferreira, GC; Ferreira, GK; Fochesato, CM; Gonçalves, CL; Jeremias, IC; Moreira, J; Rezin, GT; Romão, PR; Scaini, G; Streck, EL; Zugno, AI	1
Angarano, G; Angiletta, D; Bellacosa, C; Carito, V; Lillo, A; Maggi, P; Perilli, F; Regina, G; Trillo, G; Volpe, A	1
Childs, K; Post, FA; Welz, T	1
Chaddha, U; Goray, A; Kumar, AK; Lala, M; Ramachandran, G; Shah, I; Swaminathan, S; Tayal, S	1
De Gruttola, V; Stitelman, OM; van der Laan, MJ; Wester, CW	1
del Mar Gutiérrez, M; Díaz-Delfín, J; Domingo, JC; Domingo, P; Gallego-Escuredo, JM; Giralt, M; Gracia Mateo, M; Villarroya, F	1
Abgrall, S; Bommenel, T; Costagliola, D; Gilquin, J; Katlama, C; Lascaux, AS; Launay, O; Mahamat, A; Martinez, V; Meynard, JL; Pradier, C; Rouveix, E; Simon, A	1
Dia, AT; Diallo, PD; Gaye, AM; Sow, PG	1
Besson, J; Cavassini, M; Eap, CB; Favrat, B; Monnat, M; Pelet, A	1
Lueangniyomkul, A; Mankhatitham, W; Manosuthi, W	1
Debyser, Z; Desimmie, BA; Schrijvers, R	1
Bambara, RA; Demeter, LM; Dykes, C; Li, D; Liang, H; Lowe, NR; Smith, HM; Wang, J; Wu, H; Zhang, G	1
Claassen, M; Preiser, W; van der Merwe, L; van Zyl, GU; Zeier, M	1
Bánhegyi, D; Bannister, W; Bellido, R; Betancor, G; Bogner, J; Clotet, B; Cozzi-Lepri, A; Gargalianos, P; Kisic, M; Lundgren, J; Martinez-Picado, J; Menéndez-Arias, L; Paredes, R; Pou, C; Puertas, MC	1
Bogner, JR; Castagna, A; Clotet, B; Cozzi-Lepri, A; Kjaer, J; Kronborg, G; Lundgren, JD; Phillips, AN; Von Wyl, V	1
Aleixo, AW; Arruda, MB; de M Brindeiro, R; Greco, DB; Martins, AN; Pires, AF; Tanuri, A	1
Calis, JC; de Wit, TF; Geelen, SP; Sigaloff, KC; van Vugt, M	1
Nsanzabana, C; Rosenthal, PJ	1
Bhavani, PK; Dilip, M; Iliayas, S; Menon, PA; Narendran, G; Padmapriyadarsini, C; Ponnuraja, C; Pooranagangadevi, NP; Ramachandran, R; Ramesh Kumar, S; Selvaraju, S; Swaminathan, S; Venkatesan, P	1
Alcaro, S; Alteri, C; Artese, A; Bertoli, A; Calvez, V; Ceccherini-Silberstein, F; Costa, G; Descamps, D; Flandre, P; Forbici, F; Marcelin, AG; Masquelier, B; Ortuso, F; Parrotta, L; Perno, CF; Santoro, MM; Sing, T; Svicher, V	1
Anwikar, SR; Bandekar, MS; Kshirsagar, NA; Pazare, AP; Smrati, B; Tatke, PA	1
Ananworanich, J; Bhakeecheep, S; Bowonwattanuwong, C; Bunupuradah, T; Chetchotisakd, P; Hirschel, B; Jirajariyavej, S; Kantipong, P; Klinbuayaem, V; Munsakul, W; Petoumenos, K; Prasithsirikul, W; Ruxrungtham, K; Sirivichayakul, S; Sungkanuparph, S	1
Giaquinto, C; Penazzato, M	1
Davis, PH; Minkara, MS; Radhakrishnan, ML	1
Chandy, S; Ekstrand, M; Heylen, E; Vallabhaneni, S	1
Amzal, B; Buranawanitchakorn, Y; Eiamsirikit, N; Jourdain, G; Lallemant, M; Lertkoonalak, R; McIntosh, K; Mekviwattanawong, S; Ngo-Giang-Huong, N; Sang-a-gad, P; Tansuphasawasdikul, S; Yutthakasemsunt, N	1
Beck-Sagué, CM; Fernandez, AD; Leonardo-Guerrero, J; Nicholas, SW; Roman-Pouriet, J; Schmidt, NC	1
Manosuthi, W; Wongsawat, J	1
Bettinger, D; Bouvier-Alias, M; Calvez, V; Cottalorda, J; Delaugerre, C; Descamps, D; Flandre, P; Henquell, C; Izopet, J; Marcelin, AG; Masquelier, B; Morand-Joubert, L; Rogez, S; Ruffault, A; Signori-Schmuck, A; Tamalet, C; Trabaud, MA; Vallet, S	1
Beijnen, JH; Huitema, AD; Kromdijk, W; Mulder, JW; Rosing, H; Smit, PM	1
Bussmann, H; deGruttola, V; Marlink, RG; Stitelman, OM; van der Laan, MJ; Wester, CW	1
Burger, D; Heil, SG; Lindemans, J; Schenk, PW; van der Ende, ME; van der Heiden, I; van Schaik, RH	1
Kanki, PJ; Shafer, RW; Tang, MW	1
Agu, KA; Akpoigbe, KJ; Badru, T; Chabikuli, O; Eluwa, GI; Hamelmann, C	1
Anglaret, X; Chu, J; Danel, C; Eholié, S; Freedberg, KA; Gabillard, D; Hsu, HE; Moh, R; Ouattara, EN; Walensky, RP; Wong, AY	1
Mofenson, LM; Nachega, JB; Uthman, O	1
Luaengniyomkul, A; Mankhatitham, W; Manosuthi, W	1
Anquetil, D; Deshpande, A; Fleury, HJ; Le Bihan, L; Pinson, PR; Zongo, D	1
Abgrall, S; Bansi, L; Bucher, HC; Cain, LE; Casabona, J; Costagliola, D; de Wolf, F; del Amo, J; Elzi, L; Esteve, A; Hernán, MA; Justice, A; Lodi, S; Logan, R; Meyer, L; Moreno, S; Muga, R; Pérez-Hoyos, S; Phillips, A; Robins, JM; Sabin, C; Seng, R; Sterne, JA; Tate, J; Touloumi, G; van Sighem, A; Vourli, G	1
Balamane, M; Fessel, WJ; Katzenstein, DA; Melikian, GL; Shafer, RW; Varghese, V	1
Back, D; Byakika-Kibwika, P; de Vries, PJ; Hanpithakpong, W; Katabira, E; Khoo, S; Lamorde, M; Lindegardh, N; Mayanja-Kizza, H; Mayito, J; Merry, C; Nabukeera, L; Namakula, R; Ntale, M; Pakker, N; Ryan, M; Tarning, J	1
Dellamonica, P; Di Perri, G; Garraffo, R	1
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Kamuhabwa, AA; Maganda, BA; Minzi, OM; Ngasala, B; Sasi, PG	1
Chen, HJ; Deng, M; Jiang, HY; Ruan, B; Yang, Y; Zhang, MN	1
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Cavadas, C; Costa, S; do Céu Sousa, M; Machado, M	1
Castelnuovo, B; Kambugu, A; Kamya, M; Kiragga, A; Mubiru, F; Reynolds, SJ	1
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Dudley, D; Fernandes, JC; Gonçalves, GS; Keiko Toma, H; L Machado, S; O'Connor, D; Tanuri, A	1
Bonczkowski, P; Borch, A; De Scheerder, MA; De Spiegelaere, W; Koenig, R; Malatinkova, E; Melkova, Z; Vandekerckhove, L	1
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Irlam, JH; Mbuagbaw, L; Mursleen, S; Rutherford, GW; Siegfried, N; Spaulding, AB	1
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Naudé, Y; Rohwer, ER; Wooding, M	1
Abrams, EJ; Coovadia, A; Hunt, G; Kuhn, L; Mbete, N; Murnane, PM; Patel, F; Shiau, S; Strehlau, R	2
Bakeera-Kitaka, S; Gibb, DM; Katuramu, R; Kekitiinwa, A; Mhute, T; Musiime, V; Senfuma, O; Spyer, M; Szubert, AJ; Walker, AS	1
Cohen, CR; Kiarie, J; Morroni, C; Patel, RC; Scarsi, KK; Sripipatana, T	1
Battegay, M; Berger, B; Duthaler, U; Erb, S; Gaugler, S; Haschke, M; Krähenbühl, S; Letang, E	1
Incardona, F; Meini, G; Mloka, D; Mugusi, F; Mugusi, S; Neogi, U; Sönnerborg, A; Svärd, J; Zazzi, M	1
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Achilles, SL; Chappell, CA; Chen, BA; Cohn, SE; Darin, KM; Lamorde, M; Mackline, H; Nakalema, S; Riddler, SA; Scarsi, KK	1
Alemu, K; Ayele, TA; Kasim, A; Kebede, Y; Shkedy, Z; Worku, A	1
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Emanuel, K; Fox, HS; Lamberty, BG; Morsey, B; Stauch, KL	1
de Mast, Q; Kinabo, GD; Mchaile, DN; Schellekens, AFA; Van de Wijer, L; van der Ven, AJAM	1
Chen, X; Fairley, CK; He, J; Jing, J; Mao, L; Sasadeusz, J; Su, S; Wei, X; Zeng, H; Zhang, L	1
Cuong, DD; Dung, NT; Dung, NTH; Haneuse, S; Kinh, NV; Matsumoto, S; Oka, S; Tanuma, J; Thuy, PTT; Trung, NV; Vu, TV	1
Dhooria, S; Gupta, K; Pandey, RM; Ranjan, S; Sinha, S; Tripathy, S	1
Awodele, O; Oshikoya, KA; Popoola, TD	1
Castelnuovo, B; Gonza, P; Kambugu, A; Kiragga, AN; Mbabazi, O; Mubiru, F; Musomba, R; Ratanshi, RP	1
Diphoko, T; Essex, M; Gaseitsiwe, S; Kasvosve, I; Makhema, J; Marlink, R; Moyo, S; Musonda, R; Novitsky, V; Okatch, H; Wainberg, M	1
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Bangsberg, DR; Boum, Y; Bwana, M; Chang, JL; Haberer, JE; Hunt, PW; Martin, JN; Musinguzi, N; Muzoora, C; Siedner, MJ; Tsai, AC	1
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Abraham, OC; Demosthenes, JP; Ghale, BC; Kannangai, R; Ramalingam, VV; Rupali, P; Varghese, GM	1
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Chendi, BH; Eyoh, A; Ikomey, GM; Jacobs, GB; Lyonga, E; Mesembe, M; Okomo Assoumou, MC; Yekwa, EL	1
Dhole, TN; Gangakhedkar, RR; Lata, S; Singh, H	1
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Huang, JP; Huang, WH; Luo, SD; Luo, XL; Mo, LD; Ni, ZY; Su, GS; Su, HZ; Wu, JY	1
Agegne, M; Amare, D; Endalamaw, D; Estifanos, F; Hussien, M; Shiferaw, MB; Temesgen, D	1
Barnard, JP; Huber, KD; Sluis-Cremer, N	1
Avenant, T; du Plessis, N; George, J; Goga, AE; Mazanderani, AH; Murray, TY; Pepper, MS; Sherman, GG; Snyman, T	1
Bukusi, EA; Cohen, CR; Jakait, B; Onono, M; Patel, RC; Thomas, K; Wools-Kaloustian, KK; Yiannoutsos, C	1
Achilles, SL; Chappell, CA; Chen, BA; Lamorde, M; Matovu, J; Nakalema, S; Neary, M; Owen, A; Scarsi, KK; Siccardi, M	1
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Banda, CG; Kalilani-Phiri, L; Khoo, SH; Lalloo, DG; Macuacua, S; Maculuve, S; Mallewa, J; Mukaka, M; Mwapasa, V; Piqueras, M; Sevene, E; Terlouw, DJ; Vala, A	1
Chen, IT; Chen, JK; Chen, YS; Lee, SS; Sy, CL; Tsai, HC; Tseng, YT; Weng, YW; Wu, KS	1
Decloedt, EH; Engelbrecht, AE; Norman, J; Rabie, H; Wiesner, L	1
Diani, E; Gibellini, D; Lanzafame, M; Lattuada, E; Luise, D; Vecchi, M; Vincenzi, M	1
Abdullah, M; Hasan, M; Teguh H, K; Yunihastuti, E	1
Bonora, S; Calcagno, A; De Benedetto, I; Guastamacchia, G; Trunfio, M	1
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Abideen, G; Adeniji, H; Adeuja, O; Agbaje, EO; Akanmu, AS; Akinleye, MO; Akinyede, AA; Busari, AW; Hassan, OO; Ken-Owotor, C; Kogbe, S; Ogunfowokan, T; Onwujuobi, AG; Oreagba, IA; Owolabi, ET; Usman, SO	1
Chen, DH; Fu, Z; Ha, B; Jackson, LN; Larsen, KP; Montabana, E; Puglisi, EV; Zhang, J	1
Bulimo, WD; Ngayo, MO; Okalebo, FA; Oluka, M	1
Essex, M; Gaseitsiwe, S; Kasvosve, I; Maseng, MJ; Moyo, S; Novitsky, V; Paganotti, GM; Russo, G; Tawe, L; Thami, PK	1
Benson, CA; Chaisson, RE; Fletcher, CV; Gupta, A; Langat, D; Mohapi, L; Mwelase, N; Omoz-Oarhe, A; Pham, MM; Podany, AT; Samaneka, W; Supparatpinyo, K; Swindells, S	1
Best, BM; Bradford, S; Capparelli, EV; Chadwick, EG; Jean-Philippe, P; Liyanage, M; McFadyen, L; Mirochnick, M; Moye, J; Nikanjam, M; Rogg, L; Vourvahis, M; Whitson, K	1
Amorim, G; Bernard, C; Bukusi, EA; Cohen, CR; Jakait, B; Mocello, AR; Musick, B; Patel, RC; Shepherd, BE; Stalter, RM; Wools-Kaloustian, K; Yiannoutsos, CT	1
Abrams, EJ; Bonner, LB; Geffner, ME; Gerschenson, M; Jao, J; Kgole, S; Kurland, IJ; Legbedze, J; Makhema, J; Masasa, G; Mmalane, M; Mmasa, KN; Mohammed, T; Moyo, S; Powis, KM; Sun, S	1
Aweeka, F; Ehrlich, H; Freeman, T; French, J; Goodwin, J; Huang, L; Kajubi, R; Kay, K; Li, F; Mwebaza, N; Ou, J; Parikh, S; Riggs, M; Ruiz-Garcia, A; Wade, M; Wang, K	1
Kunene, PN; Mahlambi, PN	1
Mahlambi, P; Ngwenya, N	1
Ariyaratne, KAM; Elwitigala, J; Inzaule, SC; Jayakody, C; Jayasena, S; Kale, D; Kurle, S; Patil, A; Perera, H; Rajapaksa, L; Samaraweera, G; Siriwardna, L	1
Gill, MM; Herrera, N; Maile, L; Masenyetse, L; Masitha, M; Mokone, M; Tukei, VJ	1
Chen, Y; Fu, G; Huang, X; Li, L; Li, Q; Li, Y; Ma, P; Qiao, Y; Su, B; Wang, H; Wang, L; Wang, R; Wu, G; Wu, X; Xin, X; Xu, J; Yang, Y; Zhang, T; Zou, H	1

Reviews

69 review(s) available for nevirapine and efavirenz

Article	Year
From 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1-jk](1,4)benzodiazepin-2(1H)-one (TIBO) to etravirine (TMC125): fifteen years of research on non-nucleoside inhibitors of HIV-1 reverse transcriptase. Journal of medicinal chemistry, 2005, Mar-24, Volume: 48, Issue:6 Topics: Anti-HIV Agents; Benzodiazepines; Drug Design; Drug Resistance, Viral; HIV Reverse Transcriptase; Imidazoles; Nitriles; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors	2005
In search of a novel anti-HIV drug: multidisciplinary coordination in the discovery of 4-[[4-[[4-[(1E)-2-cyanoethenyl]-2,6-dimethylphenyl]amino]-2- pyrimidinyl]amino]benzonitrile (R278474, rilpivirine). Journal of medicinal chemistry, 2005, Mar-24, Volume: 48, Issue:6 Topics: Administration, Oral; Anti-HIV Agents; Biological Availability; Crystallography, X-Ray; Drug Design; Drug Evaluation, Preclinical; Genome, Viral; HIV; HIV Infections; Humans; Interdisciplinary Communication; Models, Molecular; Molecular Structure; Mutation; Nitriles; Pyrimidines; Rilpivirine	2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Design, synthesis and biological evaluation of novel acetamide-substituted doravirine and its prodrugs as potent HIV-1 NNRTIs. Bioorganic & medicinal chemistry, 2019, 02-01, Volume: 27, Issue:3 Topics: Acetamides; Anti-HIV Agents; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Prodrugs; Pyridones; Reverse Transcriptase Inhibitors; Triazoles	2019
The role of non-nucleoside reverse transcriptase inhibitors (NNRTIs) in the therapy of HIV-1 infection. Antiviral research, 1998, Volume: 38, Issue:3 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Delavirdine; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Virus Replication	1998
Antiretroviral chemotherapy. Current clinical topics in infectious diseases, 1998, Volume: 18 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Delavirdine; Didanosine; Dideoxynucleosides; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Nelfinavir; Nevirapine; Oxazines; Ritonavir; Saquinavir; Stavudine; Zalcitabine; Zidovudine	1998
New reverse transcriptase inhibitors. Advances in experimental medicine and biology, 1999, Volume: 458 Topics: Adenine; Alkynes; Benzoxazines; Cyclopropanes; Delavirdine; Dideoxynucleosides; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Nevirapine; Organophosphonates; Oxazines; Prodrugs; Reverse Transcriptase Inhibitors; Soman; Uracil	1999
Antiretrovirals. Mayo Clinic proceedings, 1999, Volume: 74, Issue:12 Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Carbamates; Cyclopropanes; Delavirdine; Didanosine; Dideoxynucleosides; Female; Furans; HIV Infections; Humans; Indinavir; Lamivudine; Nelfinavir; Nevirapine; Oxazines; Pregnancy; Pregnancy Complications, Infectious; Protease Inhibitors; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Stavudine; Sulfonamides; Zalcitabine; Zidovudine	1999
Efavirenz: resistance and cross-resistance. International journal of clinical practice. Supplement, 1999, Volume: 103 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Delavirdine; Drug Resistance, Microbial; Genotype; HIV Infections; HIV-1; Humans; Mutation; Nevirapine; Oxazines; Phenotype; Reverse Transcriptase Inhibitors; Treatment Failure; Virus Replication	1999
The emerging roles of non-nucleoside reverse transcriptase inhibitors in antiretroviral therapy. Drugs, 2001, Volume: 61, Issue:1 Topics: Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Clinical Trials as Topic; Cyclopropanes; Drug Interactions; Drug Resistance; Drug Therapy, Combination; HIV Infections; HIV Protease; HIV Reverse Transcriptase; Humans; Nevirapine; Oxazines; Protease Inhibitors; Reverse Transcriptase Inhibitors	2001
International perspectives on antiretroviral resistance. Nonnucleoside reverse transcriptase inhibitor resistance. Journal of acquired immune deficiency syndromes (1999), 2001, Mar-01, Volume: 26 Suppl 1 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Clinical Trials as Topic; Cyclopropanes; Delavirdine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Nevirapine; Oxazines; Phylogeny; Point Mutation; Protein Conformation; Reverse Transcriptase Inhibitors; Virus Replication	2001
Sequencing antiretroviral drugs. AIDS (London, England), 2001, Mar-30, Volume: 15, Issue:5 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Microbial; HIV Protease; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Nevirapine; Nucleosides; Oxazines; Reverse Transcriptase Inhibitors; Sequence Analysis	2001
The role of NNRTIs in antiretroviral combination therapy: an introduction. International journal of STD & AIDS, 2001, Volume: 12 Suppl 4 Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Dideoxynucleosides; HIV Infections; Humans; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors	2001
Comparison of NNRTIs in antiretroviral-naïve patients. International journal of STD & AIDS, 2001, Volume: 12 Suppl 4 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Clinical Trials as Topic; Cyclopropanes; HIV Infections; Humans; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Statistics as Topic; Treatment Outcome; Viral Load	2001
Comparison of NNRTIs in antiretroviral-experienced patients. International journal of STD & AIDS, 2001, Volume: 12 Suppl 4 Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; HIV Infections; Humans; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Treatment Outcome	2001
Factors affecting adherence and convenience in antiretroviral therapy. International journal of STD & AIDS, 2001, Volume: 12 Suppl 4 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; HIV Infections; Humans; Nevirapine; Oxazines; Patient Compliance; Problem Solving; Reverse Transcriptase Inhibitors; Treatment Refusal	2001
Other issues: penetration into sanctuary sites, immune reconstitution and NNRTI sequencing. International journal of STD & AIDS, 2001, Volume: 12 Suppl 4 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; HIV Infections; Humans; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors	2001
Clinical pharmacokinetics of non-nucleoside reverse transcriptase inhibitors. Clinical pharmacokinetics, 2001, Volume: 40, Issue:12 Topics: Alkynes; Benzoxazines; Biological Availability; Cyclopropanes; Delavirdine; Drug Interactions; Female; Half-Life; HIV Infections; Humans; Intestinal Absorption; Male; Nevirapine; Oxazines; Pregnancy; Reverse Transcriptase Inhibitors	2001
Efficacy of highly active antiretroviral therapy in HIV-1 infected children. The Lancet. Infectious diseases, 2002, Volume: 2, Issue:2 Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Child; Clinical Trials as Topic; Cyclopropanes; Dideoxynucleosides; HIV Infections; HIV-1; Humans; Indinavir; Nelfinavir; Nevirapine; Oxazines; Ritonavir; Saquinavir	2002
Non-nucleoside HIV-1 reverse transcriptase (RT) inhibitors: past, present, and future perspectives. Current pharmaceutical design, 2002, Volume: 8, Issue:8 Topics: Acquired Immunodeficiency Syndrome; Alkynes; Anti-HIV Agents; Benzodiazepinones; Benzoxazines; Cyclopropanes; Delavirdine; Drug Design; Drug Evaluation, Preclinical; Drug Resistance, Viral; Drug Therapy, Combination; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Structure; Nevirapine; Nucleosides; Oxazines; Reverse Transcriptase Inhibitors; Spiro Compounds; Thymidine; Uridine	2002
Non-nucleoside reverse transcriptase inhibitors--an overview. International journal of STD & AIDS, 2003, Volume: 14, Issue:2 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors	2003
[Antiretrovirals]. Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 2 Topics: Acidosis, Lactic; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Didanosine; Hemophilia A; Hemorrhage; HIV Protease Inhibitors; HIV-Associated Lipodystrophy Syndrome; Humans; Indinavir; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine	2003
NNRTI hepatotoxicity: efavirenz versus nevirapine. Journal of HIV therapy, 2002, Volume: 7 Suppl 2 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Chemical and Drug Induced Liver Injury; Cyclopropanes; Hepatitis B; Hepatitis C; HIV Infections; HIV Protease Inhibitors; Humans; Liver Diseases; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors	2002
Toxicity of non-nucleoside analogue reverse transcriptase inhibitors. Seminars in liver disease, 2003, Volume: 23, Issue:2 Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Chemical and Drug Induced Liver Injury; Cyclopropanes; Delavirdine; HIV Infections; Humans; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors	2003
NNRTI choice: has 2NN changed our practice? The AIDS reader, 2003, Volume: 13, Issue:7 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Humans; Hyperlipidemias; Nevirapine; Oxazines; Patient Selection; Practice Guidelines as Topic; Practice Patterns, Physicians'; Randomized Controlled Trials as Topic; Research Design; Reverse Transcriptase Inhibitors; Time Factors; Treatment Outcome; Viral Load	2003
Protease inhibitor-sparing regimens: new evidence strengthens position. Journal of acquired immune deficiency syndromes (1999), 2003, Jun-01, Volume: 33 Suppl 1 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Clinical Protocols; Clinical Trials as Topic; Cohort Studies; Cyclopropanes; Delavirdine; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Immunosuppression Therapy; Mutation; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Viral Load	2003
[Antiretroviral-induced toxiderma in HIV-infected patients]. Presse medicale (Paris, France : 1983), 2003, Sep-06, Volume: 32, Issue:28 Topics: Alkynes; Anti-HIV Agents; Anti-Inflammatory Agents; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Hypersensitivity; Exanthema; Histamine H1 Antagonists; HIV Infections; HIV Protease Inhibitors; Humans; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Risk Factors; Steroids; Stevens-Johnson Syndrome	2003
Perspectives on HAART: switch maintenance therapy. International journal of STD & AIDS, 2003, Volume: 14, Issue:9 Topics: Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Dideoxynucleosides; HIV Infections; HIV Protease Inhibitors; Humans; Lipodystrophy; Metabolic Diseases; Nevirapine; Oxazines; Patient Compliance; Reverse Transcriptase Inhibitors	2003
Issues in antiretroviral toxicity. The AIDS reader, 2003, Volume: 13, Issue:10 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Exanthema; Female; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Male; Nevirapine; Oxazines; Pregnancy; Quality of Life; Randomized Controlled Trials as Topic	2003
The continuing evolution of HIV therapy. The AIDS reader, 2003, Volume: 13, Issue:12 Topics: Adenine; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Carbamates; CD4 Lymphocyte Count; Cyclopropanes; Delayed-Action Preparations; Deoxycytidine; Didanosine; Dideoxynucleosides; Drug Monitoring; Emtricitabine; Furans; HIV Infections; Humans; Lamivudine; Nevirapine; Oligopeptides; Organophosphates; Organophosphonates; Organophosphorus Compounds; Oxazines; Pyridines; Randomized Controlled Trials as Topic; Stavudine; Sulfonamides; Tenofovir; Treatment Outcome; Viral Load; Zidovudine	2003
Clinical utility of current NNRTIs and perspectives of new agents in this class under development. Antiviral chemistry & chemotherapy, 2004, Volume: 15, Issue:3 Topics: Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Delavirdine; Drug Resistance, Viral; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors	2004
[Progress in HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs)]. Yao xue xue bao = Acta pharmaceutica Sinica, 2004, Volume: 39, Issue:8 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Coumarins; Cyclopropanes; Delavirdine; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Conformation; Molecular Structure; Nevirapine; Oxazines; Pyranocoumarins; Reverse Transcriptase Inhibitors	2004
Adverse effects of antiretroviral therapy for HIV infection: a review of selected topics. Expert opinion on drug safety, 2005, Volume: 4, Issue:2 Topics: Adenine; Alkynes; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cardiovascular Diseases; Cyclopropanes; Drug Monitoring; Drug Therapy, Combination; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Kidney Diseases; Lopinavir; Metabolic Syndrome; Nevirapine; Organophosphonates; Oxazines; Pyrimidinones; Risk Factors; Tenofovir	2005
Do non-nucleoside reverse transcriptase inhibitors contribute to lipodystrophy? Drug safety, 2005, Volume: 28, Issue:12 Topics: Alkynes; Anti-Retroviral Agents; Benzoxazines; Cardiovascular Diseases; Cyclopropanes; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Metabolic Syndrome; Nevirapine; Oxazines; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Risk Factors; Stavudine; Zidovudine	2005
HIV infection. Clinical evidence, 2005, Issue:14 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; Early Diagnosis; HIV Infections; HIV Protease Inhibitors; Humans; Infectious Disease Transmission, Patient-to-Professional; Nevirapine; Oxazines; Sexually Transmitted Diseases	2005
[The use of the non-nucleoside reverse transcriptase inhibitors nevirapine and efavirenz in the treatment of patients with a chronic HIV-I infection]. Nederlands tijdschrift voor geneeskunde, 2006, Aug-05, Volume: 150, Issue:31 Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Treatment Outcome	2006
HIV infection. Clinical evidence, 2006, Issue:15 Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; Early Diagnosis; HIV Infections; HIV Protease Inhibitors; Humans; Infectious Disease Transmission, Patient-to-Professional; Nevirapine; Sexually Transmitted Diseases	2006
Efavirenz and nevirapine in HIV-1 infection : is there a role for clinical pharmacokinetic monitoring? Clinical pharmacokinetics, 2007, Volume: 46, Issue:2 Topics: Algorithms; Alkynes; Anti-HIV Agents; Benzoxazines; Chemical and Drug Induced Liver Injury; Cyclopropanes; Decision Support Techniques; Drug Interactions; Drug Monitoring; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Nevirapine; Oxazines; Patient Selection; Pharmacogenetics; Practice Guidelines as Topic; Reverse Transcriptase Inhibitors	2007
Liver toxicity induced by non-nucleoside reverse transcriptase inhibitors. The Journal of antimicrobial chemotherapy, 2007, Volume: 59, Issue:3 Topics: Alanine Transaminase; Alkynes; Anti-HIV Agents; Aspartate Aminotransferases; Benzoxazines; Chemical and Drug Induced Liver Injury; Cyclopropanes; Drug Hypersensitivity; Humans; Liver; Nevirapine; Reverse Transcriptase Inhibitors; Risk Factors	2007
Neuropsychiatric side effects of efavirenz therapy. Expert opinion on drug safety, 2007, Volume: 6, Issue:2 Topics: Alkynes; Benzoxazines; Cyclopropanes; Humans; Mental Disorders; Neuropsychological Tests; Nevirapine; Oxazines	2007
Is it safe to switch between efavirenz and nevirapine in the event of toxicity? The Lancet. Infectious diseases, 2007, Volume: 7, Issue:11 Topics: Alkynes; Benzoxazines; Chemical and Drug Induced Liver Injury; Cross Reactions; Cyclopropanes; Drug Eruptions; HIV Infections; Humans; Nevirapine; Reverse Transcriptase Inhibitors	2007
A multimodal, evidence-based approach to achieve lipid targets in the treatment of antiretroviral-associated dyslipidemia: case report and review of the literature. Pharmacotherapy, 2008, Volume: 28, Issue:7 Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Dyslipidemias; Fluorobenzenes; HIV Infections; Humans; Hypolipidemic Agents; Male; Middle Aged; Nevirapine; Patient Compliance; Pyrimidines; Reverse Transcriptase Inhibitors; Rosuvastatin Calcium; Sulfonamides	2008
Pharmacogenomics of antiretrovirals. Recent patents on anti-infective drug discovery, 2008, Volume: 3, Issue:2 Topics: Alkynes; Anti-Retroviral Agents; Aryl Hydrocarbon Hydroxylases; Atazanavir Sulfate; Benzoxazines; Central Nervous System Diseases; Cyclopropanes; Cytochrome P-450 CYP2B6; Dideoxynucleosides; Drug Hypersensitivity; Drug Resistance, Viral; Dyslipidemias; Genetic Predisposition to Disease; Genetic Testing; Glucuronosyltransferase; HLA Antigens; Humans; Hyperbilirubinemia; Nevirapine; Oligopeptides; Oxidoreductases, N-Demethylating; Patents as Topic; Patient Selection; Pharmacogenetics; Pyridines; Ritonavir	2008
Pharmacogenetics of antiretrovirals. Antiviral research, 2010, Volume: 85, Issue:1 Topics: Alkynes; Anti-HIV Agents; Aryl Hydrocarbon Hydroxylases; Atazanavir Sulfate; Benzoxazines; Cyclopropanes; Cytochrome P-450 CYP2B6; Dideoxynucleosides; Glucuronosyltransferase; HIV Infections; HLA-A Antigens; HLA-B Antigens; HLA-DRB1 Chains; Humans; Nevirapine; Oligopeptides; Oxidoreductases, N-Demethylating; Pharmacogenetics; Pyridines	2010
Dose adjustment of the non-nucleoside reverse transcriptase inhibitors during concurrent rifampicin-containing tuberculosis therapy: one size does not fit all. Expert opinion on drug metabolism & toxicology, 2010, Volume: 6, Issue:1 Topics: Adult; Alkynes; Antitubercular Agents; Benzoxazines; Child; Cyclopropanes; Drug Interactions; HIV Infections; Humans; Nevirapine; Reverse Transcriptase Inhibitors; Rifampin; Tuberculosis	2010
Tenofovir or zidovudine in three-drug combination therapy with one nucleoside reverse transcriptase inhibitor and one non-nucleoside reverse transcriptase inhibitor for initial treatment of HIV infection in antiretroviral-naïve individuals. The Cochrane database of systematic reviews, 2010, Oct-06, Issue:10 Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Child; Cyclopropanes; Deoxycytidine; Drug Therapy, Combination; Emtricitabine; HIV Infections; Humans; Lamivudine; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine	2010
The toxicogenetics of antiretroviral therapy: the evil inside. Current medicinal chemistry, 2011, Volume: 18, Issue:2 Topics: Alkynes; Anti-Retroviral Agents; Atazanavir Sulfate; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Hypersensitivity; Genetic Variation; Humans; Nevirapine; Oligopeptides; Polymorphism, Single Nucleotide; Pyridines; Reverse Transcriptase Inhibitors; Toxicogenetics	2011
Efavirenz or nevirapine in three-drug combination therapy with two nucleoside-reverse transcriptase inhibitors for initial treatment of HIV infection in antiretroviral-naïve individuals. The Cochrane database of systematic reviews, 2010, Dec-08, Issue:12 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; HIV Infections; Humans; Nevirapine; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors	2010
HIV-1-resistance-associated mutations after failure of first-line antiretroviral treatment among children in resource-poor regions: a systematic review. The Lancet. Infectious diseases, 2011, Volume: 11, Issue:10 Topics: Adolescent; Africa; Alkynes; Anti-HIV Agents; Asia; Benzoxazines; Child; Child, Preschool; Cross-Sectional Studies; Cyclopropanes; Developing Countries; Drug Resistance, Viral; Female; Health Resources; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Latin America; Lopinavir; Male; Mutation; Nevirapine; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Treatment Failure; Viral Load; Zidovudine	2011
Role of non-nucleoside reverse transcriptase inhibitors in treating HIV-infected children. Drugs, 2011, Nov-12, Volume: 71, Issue:16 Topics: Adolescent; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Child; Child, Preschool; Cyclopropanes; HIV Infections; Humans; Infant; Nevirapine; Nitriles; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; Rilpivirine	2011
A review of the virological efficacy of the 4 World Health Organization-recommended tenofovir-containing regimens for initial HIV therapy. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2012, Volume: 54, Issue:6 Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Deoxycytidine; Drug Therapy, Combination; Emtricitabine; HIV Infections; Humans; Lamivudine; Nevirapine; Organophosphonates; Tenofovir; Treatment Failure; Viral Load; World Health Organization	2012
NNRTIs: future prospects. Medecine et maladies infectieuses, 2012, Volume: 42, Issue:7 Topics: Alkynes; Benzoxazines; Cyclopropanes; Forecasting; HIV Infections; Humans; Nevirapine; Reverse Transcriptase Inhibitors	2012
Adverse events associated with nevirapine and efavirenz-based first-line antiretroviral therapy: a systematic review and meta-analysis. AIDS (London, England), 2013, Jun-01, Volume: 27, Issue:9 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Child; Cyclopropanes; HIV Infections; Humans; Nevirapine; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors	2013
Drug interactions between antiretrovirals and hormonal contraceptives. Expert opinion on drug metabolism & toxicology, 2013, Volume: 9, Issue:5 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Contraceptive Agents, Female; Cyclopropanes; Drug Interactions; Female; HIV Seropositivity; Humans; Medroxyprogesterone Acetate; Nevirapine; Pregnancy; Pregnancy, Unplanned; Protease Inhibitors; Ritonavir	2013
HIV drug resistance in mothers and infants following use of antiretrovirals to prevent mother-to-child transmission. Current HIV research, 2013, Volume: 11, Issue:2 Topics: Alkynes; Anti-HIV Agents; Aptamers, Nucleotide; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Developing Countries; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Male; Mothers; Nevirapine; Point Mutation; Pregnancy; Pregnancy Complications, Infectious; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Sentinel Surveillance; Sequence Analysis, DNA; Viral Load; Zidovudine	2013
Abacavir-based triple nucleoside regimens for maintenance therapy in patients with HIV. The Cochrane database of systematic reviews, 2013, Jun-05, Issue:6 Topics: Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Dideoxynucleosides; Drug Substitution; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lipids; Maintenance Chemotherapy; Middle Aged; Nevirapine; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Treatment Failure; Viral Load; Young Adult; Zidovudine	2013
Outcomes for efavirenz versus nevirapine-containing regimens for treatment of HIV-1 infection: a systematic review and meta-analysis. PloS one, 2013, Volume: 8, Issue:7 Topics: Alkynes; Benzoxazines; Cyclopropanes; HIV Infections; HIV-1; Humans; Nevirapine; Treatment Outcome; Tuberculosis; Withholding Treatment	2013
Nevirapine-based regimens in HIV-infected antiretroviral-naive patients: systematic review and meta-analysis of randomized controlled trials. PloS one, 2013, Volume: 8, Issue:10 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Nevirapine; Randomized Controlled Trials as Topic; Ritonavir; Treatment Outcome	2013
Nevirapine versus efavirenz for patients co-infected with HIV and tuberculosis: a systematic review and meta-analysis. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2014, Volume: 25 Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antitubercular Agents; Benzoxazines; CD4 Lymphocyte Count; Clinical Trials as Topic; Coinfection; Cyclopropanes; HIV Infections; Humans; Nevirapine; Rifampin; Treatment Outcome; Tuberculosis; Viral Load	2014
Pharmacogenetics of CYP2B6, CYP2A6 and UGT2B7 in HIV treatment in African populations: focus on efavirenz and nevirapine. Drug metabolism reviews, 2015, Volume: 47, Issue:2 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Black People; Cyclopropanes; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2B6; Glucuronosyltransferase; HIV Infections; Humans; Metabolic Detoxication, Phase I; Metabolic Detoxication, Phase II; Nevirapine; Pharmacogenetics; Polymorphism, Single Nucleotide	2015
Challenges regarding analysis of unbound fraction of highly bound protein antiretroviral drugs in several biological matrices: lack of harmonisation and guidelines. Drug discovery today, 2015, Volume: 20, Issue:4 Topics: Alkynes; Animals; Anti-Retroviral Agents; Benzoxazines; Cyclopropanes; Drug Monitoring; Humans; Nevirapine; Practice Guidelines as Topic; Predictive Value of Tests; Protein Binding; Reproducibility of Results	2015
Pregnancy rates in HIV-positive women using contraceptives and efavirenz-based or nevirapine-based antiretroviral therapy in Kenya: a retrospective cohort study. The lancet. HIV, 2015, Volume: 2, Issue:11 Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Contraceptive Agents; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; Humans; Kenya; Longitudinal Studies; Nevirapine; Pregnancy; Pregnancy Rate; Retrospective Studies; Treatment Outcome	2015
Efavirenz-based antiretroviral therapy versus nevirapine-including regimens for prevention of mother-to-child transmission of HIV option B plus in resource-limited settings: is there anything missing? Expert review of anti-infective therapy, 2016, Volume: 14, Issue:1 Topics: Adult; Africa South of the Sahara; Alkynes; Benzoxazines; Clinical Trials as Topic; Cyclopropanes; Developing Countries; Female; HIV Infections; HIV-1; Humans; Infant; Infectious Disease Transmission, Vertical; Nevirapine; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors	2016
Pharmacogenetics of non-nucleoside reverse transcriptase inhibitors (NNRTIs) in resource-limited settings: Influence on antiretroviral therapy response and concomitant anti-tubercular, antimalarial and contraceptive treatments. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 2016, Volume: 37 Topics: Alkynes; Anti-HIV Agents; Antimalarials; Antitubercular Agents; Benzoxazines; Contraceptive Agents; Cyclopropanes; Cytochrome P-450 Enzyme System; Drug Interactions; Glucuronosyltransferase; Humans; Nevirapine; Polymorphism, Single Nucleotide; Reverse Transcriptase Inhibitors	2016
Efavirenz or nevirapine in three-drug combination therapy with two nucleoside or nucleotide-reverse transcriptase inhibitors for initial treatment of HIV infection in antiretroviral-naïve individuals. The Cochrane database of systematic reviews, 2016, 12-10, Volume: 12 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; HIV Infections; Humans; Nevirapine; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Viral Load	2016
Concomitant contraceptive implant and efavirenz use in women living with HIV: perspectives on current evidence and policy implications for family planning and HIV treatment guidelines. Journal of the International AIDS Society, 2017, 05-11, Volume: 20, Issue:1 Topics: Adult; Alkynes; Benzoxazines; Contraception; Contraceptive Agents; Counseling; Cyclopropanes; Drug Implants; Family Planning Services; Female; Health Policy; HIV Infections; Humans; Kenya; Nevirapine; Pregnancy; Pregnancy Rate; Progestins; South Africa; Young Adult	2017
Choice of initial antiretroviral drugs and treatment outcomes among HIV-infected patients in sub-Saharan Africa: systematic review and meta-analysis of observational studies. Systematic reviews, 2017, 08-25, Volume: 6, Issue:1 Topics: Africa South of the Sahara; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; HIV Infections; Humans; Incidence; Nevirapine; Reverse Transcriptase Inhibitors; Treatment Outcome	2017
Comparative safety and effectiveness of perinatal antiretroviral therapies for HIV-infected women and their children: Systematic review and network meta-analysis including different study designs. PloS one, 2018, Volume: 13, Issue:6 Topics: Abnormalities, Drug-Induced; Alkynes; Anti-HIV Agents; Benzoxazines; Child; Congenital Abnormalities; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Infant, Low Birth Weight; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Network Meta-Analysis; Nevirapine; Perinatal Care; Pregnancy; Pregnancy Complications, Infectious; Stavudine; Stillbirth; Zidovudine	2018
A review of the potential mechanisms of neuronal toxicity associated with antiretroviral drugs. Journal of neurovirology, 2020, Volume: 26, Issue:5 Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Astrocytes; Atazanavir Sulfate; Benzoxazines; Central Nervous System; Cognitive Dysfunction; Cyclopropanes; Dideoxynucleosides; Endothelial Cells; HIV Infections; Humans; Neurons; Nevirapine; Nitriles; Oligodendroglia; Pyrimidines	2020

Trials

73 trial(s) available for nevirapine and efavirenz

Article	Year
Limits of deep salvage antiretroviral therapy with nelfinavir plus either efavirenz or nevirapine, in highly pre-treated patients with HIV disease. International journal of antimicrobial agents, 2001, Volume: 17, Issue:6 Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Female; HIV Infections; Humans; Male; Nelfinavir; Nevirapine; Oxazines; Prospective Studies; Salvage Therapy	2001
The steady-state pharmacokinetics of efavirenz and nevirapine when used in combination in human immunodeficiency virus type 1-infected persons. The Journal of infectious diseases, 2001, Jul-01, Volume: 184, Issue:1 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Administration Schedule; Drug Therapy, Combination; Half-Life; HIV Infections; HIV-1; Humans; Male; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Viral Load	2001
Virological suppression at 6 months is related to choice of initial regimen in antiretroviral-naive patients: a cohort study. AIDS (London, England), 2002, Jan-04, Volume: 16, Issue:1 Topics: Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; Cohort Studies; Cyclopropanes; Drug Administration Schedule; Female; HIV Infections; HIV-1; Humans; Indinavir; Male; Middle Aged; Nelfinavir; Nevirapine; Oxazines; Protease Inhibitors; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Viral Load	2002
Virological, immunological, and clinical impact of switching from protease inhibitors to nevirapine or to efavirenz in patients with human immunodeficiency virus infection and long-lasting viral suppression. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2002, Feb-15, Volume: 34, Issue:4 Topics: Alkynes; Benzoxazines; Cyclopropanes; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Nevirapine; Oxazines; Prospective Studies; Treatment Outcome	2002
Therapeutic effects of nonnucleoside reverse transcriptase inhibitors on the central nervous system in HIV-1-infected patients. Journal of acquired immune deficiency syndromes (1999), 2002, Apr-01, Volume: 29, Issue:4 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Central Nervous System Viral Diseases; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nevirapine; Oxazines; Psychomotor Performance; Reverse Transcriptase Inhibitors; Treatment Outcome	2002
Substitution of nevirapine, efavirenz, or abacavir for protease inhibitors in patients with human immunodeficiency virus infection. The New England journal of medicine, 2003, Sep-11, Volume: 349, Issue:11 Topics: Adult; Aged; Alkynes; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Disease Progression; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Male; Middle Aged; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Failure	2003
Treatment of HIV-infected patients with a combination of efavirenz, nevirapine and nucleoside reverse transcriptase inhibitors. HIV medicine, 2004, Volume: 5, Issue:2 Topics: Adult; Alkynes; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Nevirapine; Nucleosides; Oxazines; Pilot Projects; Reverse Transcriptase Inhibitors; Treatment Outcome	2004
Efavirenz versus nevirapine in current clinical practice: a prospective, open-label observational study. Journal of acquired immune deficiency syndromes (1999), 2004, Apr-15, Volume: 35, Issue:5 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Central Nervous System Diseases; Cyclopropanes; Female; Follow-Up Studies; Gynecomastia; HIV Infections; Humans; Hypersensitivity; Liver Diseases; Male; Metabolic Diseases; Nevirapine; Oxazines; Pancreatic Diseases; Prospective Studies; Reverse Transcriptase Inhibitors; Viral Load	2004
Dose escalation or immediate full dose when switching from efavirenz to nevirapine-based highly active antiretroviral therapy in HIV-1-infected individuals? AIDS (London, England), 2004, Feb-20, Volume: 18, Issue:3 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Administration Schedule; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nevirapine; Oxazines; Viral Load	2004
Comparison of first-line antiretroviral therapy with regimens including nevirapine, efavirenz, or both drugs, plus stavudine and lamivudine: a randomised open-label trial, the 2NN Study. Lancet (London, England), 2004, Apr-17, Volume: 363, Issue:9417 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Male; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Failure	2004
A comparison of the CD4 response to antiretroviral regimens in patients commencing therapy with low CD4 counts. The Journal of antimicrobial chemotherapy, 2004, Volume: 54, Issue:2 Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Male; Nevirapine; Oxazines; Proportional Hazards Models; Prospective Studies; Reverse Transcriptase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction	2004
Evaluation of the virological and metabolic effects of switching protease inhibitor combination antiretroviral therapy to nevirapine-based therapy for the treatment of HIV infection. AIDS research and human retroviruses, 2004, Volume: 20, Issue:6 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Blood Glucose; Body Composition; Bone Density; C-Peptide; Cyclopropanes; Drug Therapy, Combination; Female; Glucagon; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Insulin; Insulin Resistance; Lipids; Lipoproteins; Male; Nevirapine; Oxazines; Pilot Projects; RNA, Viral; Viral Load	2004
Nevirapine and efavirenz elicit different changes in lipid profiles in antiretroviral-therapy-naive patients infected with HIV-1. PLoS medicine, 2004, Volume: 1, Issue:1 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cholesterol, HDL; Cyclopropanes; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nevirapine; Oxazines	2004
Quality of life in patients treated with first-line antiretroviral therapy containing nevirapine and/or efavirenz. Antiviral therapy, 2004, Volume: 9, Issue:5 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Nevirapine; Oxazines; Quality of Life; Reverse Transcriptase Inhibitors; Treatment Outcome	2004
Detection of minority populations of HIV-1 expressing the K103N resistance mutation in patients failing nevirapine. Journal of acquired immune deficiency syndromes (1999), 2005, Jan-01, Volume: 38, Issue:1 Topics: Adult; Alkynes; Amino Acid Substitution; Anti-HIV Agents; Base Sequence; Benzoxazines; Cyclopropanes; DNA, Viral; Drug Resistance, Viral; Genes, pol; HIV Infections; HIV-1; Humans; Nevirapine; Oxazines; Point Mutation; Prospective Studies; Reverse Transcriptase Inhibitors; Salvage Therapy; Treatment Failure	2005
Incidence and risk factors for rash in Thai patients randomized to regimens with nevirapine, efavirenz or both drugs. AIDS (London, England), 2005, Jan-28, Volume: 19, Issue:2 Topics: Adult; Alkynes; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Administration Schedule; Drug Therapy, Combination; Exanthema; Female; HIV Seropositivity; Humans; Incidence; Male; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Risk Factors; Thailand; Treatment Outcome	2005
[Rashes in HIV-infected patients undergoing therapy with nevirapine or efavirenz]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2005, Volume: 56, Issue:9 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Comorbidity; Cyclopropanes; Exanthema; Female; Germany; HIV Infections; Humans; Male; Nevirapine; Outcome Assessment, Health Care; Oxazines; Prevalence; Prognosis; Risk Assessment; Risk Factors	2005
Plasma HIV-1 RNA decline within the first two weeks of treatment is comparable for nevirapine, efavirenz, or both drugs combined and is not predictive of long-term virologic efficacy: A 2NN substudy. Journal of acquired immune deficiency syndromes (1999), 2005, Mar-01, Volume: 38, Issue:3 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Kinetics; Lamivudine; Male; Nevirapine; Oxazines; Proportional Hazards Models; RNA, Viral; Stavudine; Treatment Outcome	2005
Nevirapine and efavirenz pharmacokinetics and covariate analysis in the 2NN study. Antiviral therapy, 2005, Volume: 10, Issue:1 Topics: Adult; Alkynes; Analysis of Variance; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Stavudine	2005
The effect of baseline CD4 cell count and HIV-1 viral load on the efficacy and safety of nevirapine or efavirenz-based first-line HAART. AIDS (London, England), 2005, Mar-25, Volume: 19, Issue:5 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cyclopropanes; Exanthema; Female; HIV Infections; HIV-1; Humans; Male; Nevirapine; Oxazines; Sex Factors; Viral Load	2005
Metabolic benefits 24 months after replacing a protease inhibitor with abacavir, efavirenz or nevirapine. AIDS (London, England), 2005, Jun-10, Volume: 19, Issue:9 Topics: Adult; Alkynes; Anthropometry; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Blood Glucose; Cholesterol; Cholesterol, HDL; Cyclopropanes; Dideoxynucleosides; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Insulin Resistance; Lipodystrophy; Male; Middle Aged; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Triglycerides	2005
Substitution of nevirapine or efavirenz for protease inhibitor versus lipid-lowering therapy for the management of dyslipidaemia. AIDS (London, England), 2005, Jul-01, Volume: 19, Issue:10 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Bezafibrate; Cyclopropanes; Female; HIV Infections; Humans; Hyperlipidemias; Hypolipidemic Agents; Male; Nevirapine; Oxazines; Pravastatin; Protease Inhibitors; Reverse Transcriptase Inhibitors; Treatment Outcome	2005
Comparison of efavirenz and nevirapine in HIV-infected patients (NEEF Cohort). International journal of STD & AIDS, 2005, Volume: 16, Issue:6 Topics: Alkynes; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Male; Nevirapine; Oxazines; Prospective Studies; Viral Load	2005
Genotypic and phenotypic resistance patterns at virological failure in a simplification trial with nevirapine, efavirenz or abacavir. AIDS (London, England), 2005, Sep-02, Volume: 19, Issue:13 Topics: Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Resistance, Viral; Follow-Up Studies; Genotype; HIV Infections; HIV-1; Humans; Middle Aged; Mutation; Nevirapine; Oxazines; Phenotype; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Failure	2005
Highly active antiretroviral treatment containing efavirenz or nevirapine and related toxicity in the TREAT Asia HIV Observational Database. Journal of acquired immune deficiency syndromes (1999), 2006, Dec-01, Volume: 43, Issue:4 Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Chemical and Drug Induced Liver Injury; Cyclopropanes; Drug Therapy, Combination; Exanthema; HIV Infections; HIV-1; Humans; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors	2006
Depo-medroxyprogesterone in women on antiretroviral therapy: effective contraception and lack of clinically significant interactions. Clinical pharmacology and therapeutics, 2007, Volume: 81, Issue:2 Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Area Under Curve; Benzoxazines; CD4 Lymphocyte Count; Chromatography, Liquid; Cyclopropanes; Drug Administration Schedule; Drug Interactions; Female; Half-Life; HIV Infections; HIV Protease Inhibitors; Humans; Injections; Medroxyprogesterone Acetate; Middle Aged; Nelfinavir; Nevirapine; Ovulation Inhibition; Oxazines; Progesterone; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors	2007
Three-year follow-up of protease inhibitor-based regimen simplification in HIV-infected patients. AIDS (London, England), 2007, Jan-30, Volume: 21, Issue:3 Topics: Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Disease Progression; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Nevirapine; Reverse Transcriptase Inhibitors; Treatment Outcome	2007
Efavirenz to nevirapine switch in HIV-1-infected patients with dyslipidemia: a randomized, controlled study. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2007, Jul-15, Volume: 45, Issue:2 Topics: Alkynes; Benzoxazines; Cholesterol, LDL; Coronary Disease; Cross-Over Studies; Cyclopropanes; Dose-Response Relationship, Drug; Drug Administration Schedule; Dyslipidemias; Female; Follow-Up Studies; HIV Infections; Humans; Male; Nevirapine; Reverse Transcriptase Inhibitors; Severity of Illness Index; Single-Blind Method; Treatment Outcome	2007
Safety of switching to nevirapine-based highly active antiretroviral therapy at elevated CD4 cell counts in a resource-constrained setting. Journal of acquired immune deficiency syndromes (1999), 2007, Aug-15, Volume: 45, Issue:5 Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Chemical and Drug Induced Liver Injury; Costs and Cost Analysis; Cyclopropanes; Female; HIV; HIV Infections; Humans; India; Liver; Liver Diseases; Male; Nevirapine; Prospective Studies; Reverse Transcriptase Inhibitors; Treatment Outcome	2007
Data shows long-term nevirapine efficacy and increases in good cholesterol. AIDS patient care and STDs, 2007, Volume: 21, Issue:8 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cholesterol, HDL; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Male; Nevirapine; Reverse Transcriptase Inhibitors; Time Factors; Treatment Outcome; Viral Load	2007
Safety and tolerability of depot medroxyprogesterone acetate among HIV-infected women on antiretroviral therapy: ACTG A5093. Contraception, 2008, Volume: 77, Issue:2 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Contraceptive Agents, Female; Cyclopropanes; Drug Interactions; Female; HIV Infections; Humans; Injections, Intramuscular; Medroxyprogesterone Acetate; Nelfinavir; Nevirapine; Ovulation Inhibition; RNA, Viral; Safety; Viral Load	2008
Plasma drug concentrations and virologic evaluations after stopping treatment with nonnucleoside reverse-transcriptase inhibitors in HIV type 1-infected children. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008, May-15, Volume: 46, Issue:10 Topics: Adolescent; Alkynes; Benzoxazines; CD4 Lymphocyte Count; CD4-CD8 Ratio; Child; Child, Preschool; Cyclopropanes; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Male; Mutation; Nevirapine; Plasma; Reverse Transcriptase Inhibitors; Time Factors; Viral Load; Withholding Treatment	2008
Efficacy and tolerability of nevirapine- versus efavirenz-containing regimens in HIV-infected Thai children. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2008, Volume: 12, Issue:6 Topics: Adolescent; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Child; Child, Preschool; Cyclopropanes; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Male; Nevirapine; Reverse Transcriptase Inhibitors; Thailand; Treatment Outcome	2008
Lymphocyte mitochondrial depolarization and apoptosis in HIV-1-infected HAART patients. Journal of acquired immune deficiency syndromes (1999), 2008, Aug-01, Volume: 48, Issue:4 Topics: Alkynes; Antiretroviral Therapy, Highly Active; Apoptosis; Benzoxazines; CD4-Positive T-Lymphocytes; Cohort Studies; Cyclopropanes; Female; HIV Infections; HIV-1; Humans; Male; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Diseases; Mitochondrial Membranes; Nevirapine; Pilot Projects; Reverse Transcriptase Inhibitors; T-Lymphocyte Subsets; T-Lymphocytes, Helper-Inducer	2008
Concomitant use of nonnucleoside analogue reverse transcriptase inhibitors and rifampicin in TB/HIV type 1-coinfected patients. AIDS research and human retroviruses, 2008, Volume: 24, Issue:7 Topics: Adult; Alkynes; Antibiotics, Antitubercular; Antiretroviral Therapy, Highly Active; Benzoxazines; Chemical and Drug Induced Liver Injury; Cyclopropanes; Drug Administration Schedule; Drug Monitoring; Female; HIV Infections; HIV-1; Humans; Male; Nevirapine; Prospective Studies; Reverse Transcriptase Inhibitors; Rifampin; Treatment Outcome; Tuberculosis	2008
Increase of R-/S-methadone enantiomer concentration ratio in serum of patients treated with either nevirapine or efavirenz. Drug metabolism letters, 2008, Volume: 2, Issue:4 Topics: Adult; Alkynes; Anti-HIV Agents; Aryl Hydrocarbon Hydroxylases; Benzoxazines; Cyclopropanes; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Drug Interactions; Enzyme Induction; Female; Follow-Up Studies; Humans; Male; Medication Adherence; Methadone; Narcotics; Nevirapine; Oxidoreductases, N-Demethylating; Stereoisomerism	2008
A randomized trial comparing plasma drug concentrations and efficacies between 2 nonnucleoside reverse-transcriptase inhibitor-based regimens in HIV-infected patients receiving rifampicin: the N2R Study. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2009, Jun-15, Volume: 48, Issue:12 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Interactions; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nevirapine; Plasma; Prospective Studies; Reverse Transcriptase Inhibitors; Rifampin; RNA, Viral; Treatment Outcome; Tuberculosis; Viral Load	2009
Antiretroviral drug-resistant mutations at baseline and at time of failure of antiretroviral therapy in HIV type 1-coinfected TB patients. AIDS research and human retroviruses, 2009, Volume: 25, Issue:11 Topics: Adult; Alkynes; Anti-HIV Agents; Antitubercular Agents; Benzoxazines; Cyclopropanes; Didanosine; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; India; Lamivudine; Male; Mutation; Nevirapine; Reverse Transcriptase Inhibitors; Treatment Failure; Tuberculosis	2009
Substitution of nevirapine because of efavirenz toxicity in AIDS clinical trials group A5095. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2010, Mar-01, Volume: 50, Issue:5 Topics: Acquired Immunodeficiency Syndrome; Adult; Alkynes; Antiviral Agents; Benzoxazines; Cyclopropanes; Female; Humans; Liver; Male; Middle Aged; Nevirapine; Withholding Treatment	2010
Pharmacokinetics of lopinavir-ritonavir with and without nonnucleoside reverse transcriptase inhibitors in Ugandan HIV-infected adults. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:7 Topics: Adult; Aged; Alkynes; Benzoxazines; Chromatography, High Pressure Liquid; Cyclopropanes; Female; HIV Infections; Humans; Lopinavir; Male; Middle Aged; Nevirapine; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Uganda	2010
Nonnucleoside reverse transcriptase inhibitor concentrations during treatment interruptions and the emergence of resistance: a substudy of the ISS-PART Trial. AIDS research and human retroviruses, 2010, Volume: 26, Issue:5 Topics: Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Young Adult	2010
Long-term effectiveness and safety of didanosine combined with lamivudine and efavirenz or nevirapine in antiretroviral-naive patients: a 9-year cohort study in Senegal. Tropical medicine & international health : TM & IH, 2011, Volume: 16, Issue:2 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Treatment Outcome; Viral Load; Zidovudine	2011
Comparative effectiveness of continuing a virologically effective first-line boosted protease inhibitor combination or of switching to a three-drug regimen containing either efavirenz, nevirapine or abacavir. The Journal of antimicrobial chemotherapy, 2011, Volume: 66, Issue:8 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cohort Studies; Cyclopropanes; Dideoxynucleosides; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Male; Nevirapine; Prospective Studies; Treatment Outcome; Viral Load	2011
Hepatotoxicity in patients co-infected with tuberculosis and HIV-1 while receiving non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy and rifampicin-containing anti-tuberculosis regimen. The Southeast Asian journal of tropical medicine and public health, 2011, Volume: 42, Issue:3 Topics: Adult; Alkynes; Antibiotics, Antitubercular; Benzoxazines; Chemical and Drug Induced Liver Injury; Cyclopropanes; Female; HIV Infections; HIV-1; Humans; Hyperbilirubinemia; Liver Function Tests; Logistic Models; Male; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; Rifampin; Risk Factors; Thailand; Tuberculosis; Young Adult	2011
Efficacy and safety of once-daily nevirapine- or efavirenz-based antiretroviral therapy in HIV-associated tuberculosis: a randomized clinical trial. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2011, Volume: 53, Issue:7 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antitubercular Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Female; HIV Infections; Humans; India; Liver Function Tests; Male; Middle Aged; Mycobacterium tuberculosis; Nevirapine; Sputum; Treatment Outcome; Tuberculosis; Viral Load	2011
Etravirine and rilpivirine resistance in HIV-1 subtype CRF01_AE-infected adults failing non-nucleoside reverse transcriptase inhibitor-based regimens. Antiviral therapy, 2011, Volume: 16, Issue:7 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; Female; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Male; Mutation; Nevirapine; Nitriles; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; Rilpivirine; RNA, Viral; Stavudine	2011
Effect modification by sex and baseline CD4+ cell count among adults receiving combination antiretroviral therapy in Botswana: results from a clinical trial. AIDS research and human retroviruses, 2012, Volume: 28, Issue:9 Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; Botswana; CD4 Lymphocyte Count; Cyclopropanes; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Likelihood Functions; Male; Middle Aged; Nevirapine; Retrospective Studies; Sex Distribution; Time Factors; Treatment Outcome; Viral Load; Young Adult	2012
Lipid profile changes in Thai HIV and tuberculosis co-infected patients receiving non-nucleoside reverse transcriptase inhibitors-based antiretroviral therapy. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2012, Volume: 95, Issue:2 Topics: Adolescent; Adult; Alkynes; Benzoxazines; Cholesterol, HDL; Coinfection; Cyclopropanes; Female; HIV Infections; Humans; Lamivudine; Lipids; Male; Middle Aged; Nevirapine; Prospective Studies; Reverse Transcriptase Inhibitors; Stavudine; Thailand; Triglycerides; Tuberculosis; Young Adult	2012
Significant pharmacokinetic interactions between artemether/lumefantrine and efavirenz or nevirapine in HIV-infected Ugandan adults. The Journal of antimicrobial chemotherapy, 2012, Volume: 67, Issue:9 Topics: Adult; Alkynes; Anti-HIV Agents; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Benzoxazines; Cross-Over Studies; Cyclopropanes; Drug Combinations; Drug Interactions; Ethanolamines; Female; Fluorenes; HIV Infections; Humans; Malaria; Male; Nevirapine; Plasma; Uganda	2012
Treatment outcomes among HIV-1 and HIV-2 infected children initiating antiretroviral therapy in a concentrated low prevalence setting in West Africa. BMC pediatrics, 2012, Jul-08, Volume: 12 Topics: Adolescent; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Child; Child, Preschool; Cohort Studies; Cyclopropanes; Drug Combinations; Female; Follow-Up Studies; Gambia; HIV Infections; HIV-1; HIV-2; Humans; Infant; Kaplan-Meier Estimate; Lamivudine; Lopinavir; Male; Nevirapine; Reverse Transcriptase Inhibitors; Ritonavir; Treatment Outcome; Viral Load; Zidovudine	2012
Influence of ABCB-1 C3435T polymorphisms on plasma nevirapine and efavirenz levels and their effects on virologic and immunological outcomes in HIV/TB co-infected Thai adults under anti-retroviral therapy. The Southeast Asian journal of tropical medicine and public health, 2012, Volume: 43, Issue:1 Topics: Adult; Alkynes; Analysis of Variance; Antiretroviral Therapy, Highly Active; Antitubercular Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Female; Genotype; HIV Infections; HIV-1; Humans; Male; Nevirapine; Polymorphism, Genetic; Real-Time Polymerase Chain Reaction; Rifampin; Thailand; Tuberculosis; Viral Load	2012
Effect of efavirenz, nevirapine, etravirine, and raltegravir administration on the pharmacokinetics of ritonavir-boosted darunavir in a population of HIV-infected patients. AIDS research and human retroviruses, 2013, Volume: 29, Issue:1 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Darunavir; Drug Synergism; Female; HIV Infections; HIV Protease Inhibitors; Humans; Male; Nevirapine; Nitriles; Pyridazines; Pyrimidines; Pyrrolidinones; Raltegravir Potassium; Ritonavir; Sulfonamides	2013
Efavirenz, in contrast to nevirapine, is associated with unfavorable progesterone and antiretroviral levels when coadministered with combined oral contraceptives. Journal of acquired immune deficiency syndromes (1999), 2013, Apr-15, Volume: 62, Issue:5 Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Contraceptives, Oral, Synthetic; Cyclopropanes; Desogestrel; Drug Interactions; Ethinyl Estradiol; Female; HIV; HIV Infections; Humans; Logistic Models; Middle Aged; Nevirapine; Progesterone; Prospective Studies; Thailand; Young Adult	2013
Nevirapine versus efavirenz for patients co-infected with HIV and tuberculosis: a randomised non-inferiority trial. The Lancet. Infectious diseases, 2013, Volume: 13, Issue:4 Topics: Adult; AIDS-Related Opportunistic Infections; Alkynes; Anti-HIV Agents; Antitubercular Agents; Benzoxazines; Coinfection; Cyclopropanes; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Mozambique; Nevirapine; Treatment Outcome; Tuberculosis; Tuberculosis, Pulmonary	2013
WHO option B+: early experience of antiretroviral therapy sequencing after cessation of breastfeeding and risk of dermatologic toxicity. Journal of acquired immune deficiency syndromes (1999), 2013, Mar-01, Volume: 62, Issue:3 Topics: Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Breast Feeding; CD4 Lymphocyte Count; Cohort Studies; Cyclopropanes; Dideoxynucleosides; Drug Eruptions; Drug Substitution; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lopinavir; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Protease Inhibitors; Ritonavir; Uganda; World Health Organization	2013
Comparing the effectiveness of efavirenz and nevirapine for first-line antiretroviral therapy in a South African multicentre cohort. International health, 2013, Volume: 5, Issue:2 Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cohort Studies; Cyclopropanes; Female; HIV Infections; Humans; Male; Middle Aged; Nevirapine; Pregnancy; Proportional Hazards Models; Reverse Transcriptase Inhibitors; South Africa; Treatment Outcome; Viral Load; Young Adult	2013
Changes in clearance, volume and bioavailability of immunosuppressants when given with HAART in HIV-1 infected liver and kidney transplant recipients. Biopharmaceutics & drug disposition, 2013, Volume: 34, Issue:8 Topics: Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Biological Availability; Cyclopropanes; Cyclosporine; Drug Interactions; Female; HIV Infections; HIV-1; Humans; Immunosuppressive Agents; Kidney Transplantation; Liver Transplantation; Male; Middle Aged; Nevirapine; Tacrolimus; Young Adult	2013
Plasma concentrations of efavirenz and nevirapine among HIV-infected patients with immunological failure attending a tertiary hospital in North-western Tanzania. PloS one, 2013, Volume: 8, Issue:9 Topics: Adult; Alkynes; Benzoxazines; Cyclopropanes; Drug Monitoring; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; Tanzania; Viral Load	2013
Early changes in hepatic function among HIV-tuberculosis patients treated with nevirapine or efavirenz along with rifampin-based anti-tuberculosis therapy. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2013, Volume: 17, Issue:12 Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Antitubercular Agents; Benzoxazines; CD4 Lymphocyte Count; Coinfection; Cyclopropanes; Female; HIV Infections; Humans; Liver; Liver Function Tests; Male; Nevirapine; Rifampin; Time Factors; Treatment Outcome; Tuberculosis; Viral Load	2013
Nevirapine versus efavirenz-based antiretroviral therapy regimens in antiretroviral-naive patients with HIV and tuberculosis infections in India: a pilot study. BMC infectious diseases, 2013, Oct-17, Volume: 13 Topics: Adult; Alkynes; Anti-Retroviral Agents; Antitubercular Agents; Benzoxazines; Coinfection; Cyclopropanes; Female; HIV Infections; Humans; India; Male; Middle Aged; Nevirapine; Pilot Projects; Rifampin; Tuberculosis	2013
Pharmacokinetics of rifampin and isoniazid in tuberculosis-HIV-coinfected patients receiving nevirapine- or efavirenz-based antiretroviral treatment. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:6 Topics: Adult; Alkynes; Antitubercular Agents; Benzoxazines; Coinfection; Cyclopropanes; Female; Half-Life; HIV Infections; Humans; Isoniazid; Male; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; Rifampin; Treatment Outcome; Tuberculosis; Young Adult	2014
Archived HIV-1 DNA resistance mutations to rilpivirine and etravirine in successfully treated HIV-1-infected individuals pre-exposed to efavirenz or nevirapine. The Journal of antimicrobial chemotherapy, 2015, Volume: 70, Issue:2 Topics: Adult; Aged; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; Female; Genotype; HIV Infections; HIV-1; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Mutation; Nevirapine; Nitriles; Pyridazines; Pyrimidines; Retreatment; Reverse Transcriptase Inhibitors; Rilpivirine; Young Adult	2015
Lipid-based nutrient supplements do not affect efavirenz but lower plasma nevirapine concentrations in Ethiopian adult HIV patients. HIV medicine, 2015, Volume: 16, Issue:7 Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Black People; Cyclopropanes; Cytochrome P-450 CYP2B6; Dietary Supplements; Ethiopia; Fatty Acids, Essential; Female; HIV Infections; Humans; Lipids; Male; Micronutrients; Nevirapine; Reverse Transcriptase Inhibitors; Urban Population	2015
Abacavir, zidovudine, or stavudine as paediatric tablets for African HIV-infected children (CHAPAS-3): an open-label, parallel-group, randomised controlled trial. The Lancet. Infectious diseases, 2016, Volume: 16, Issue:2 Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Child; Child, Preschool; Cyclopropanes; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Lamivudine; Male; Nevirapine; Stavudine; Tablets; Uganda; Zambia; Zidovudine	2016
Efavirenz-Based Antiretroviral Therapy Among Nevirapine-Exposed HIV-Infected Children in South Africa: A Randomized Clinical Trial. JAMA, 2015, Nov-03, Volume: 314, Issue:17 Topics: Alkynes; Anti-Retroviral Agents; Benzoxazines; Child; Child, Preschool; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lopinavir; Male; Nevirapine; South Africa; Viral Load	2015
Unintended Pregnancies Observed With Combined Use of the Levonorgestrel Contraceptive Implant and Efavirenz-based Antiretroviral Therapy: A Three-Arm Pharmacokinetic Evaluation Over 48 Weeks. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2016, Mar-15, Volume: 62, Issue:6 Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Contraceptive Agents, Female; Cyclopropanes; Drug Interactions; Female; HIV Infections; HIV-1; Humans; Levonorgestrel; Nevirapine; Pregnancy; Pregnancy, Unplanned; Reverse Transcriptase Inhibitors; Time Factors; Uganda	2016
The Effect of Gene Variants on Levonorgestrel Pharmacokinetics When Combined With Antiretroviral Therapy Containing Efavirenz or Nevirapine. Clinical pharmacology and therapeutics, 2017, Volume: 102, Issue:3 Topics: Adult; Alkynes; Area Under Curve; Benzoxazines; Constitutive Androstane Receptor; Contraceptive Agents, Female; Cyclopropanes; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2B6; Female; Genetic Variation; HIV Infections; Humans; Levonorgestrel; Linear Models; Multivariate Analysis; Nevirapine; Pharmacogenetics; Polymorphism, Single Nucleotide; Prospective Studies; Reverse Transcriptase Inhibitors	2017
Switching to Efavirenz Versus Remaining on Ritonavir-boosted Lopinavir in Human Immunodeficiency Virus-infected Children Exposed to Nevirapine: Long-term Outcomes of a Randomized Trial. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2017, Aug-01, Volume: 65, Issue:3 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Child, Preschool; Cyclopropanes; Female; HIV Infections; HIV-1; Humans; Infant; Lipids; Lopinavir; Male; Nevirapine; Ritonavir; RNA, Viral; Treatment Outcome	2017
Nevirapine- versus Efavirenz-based antiretroviral therapy regimens in antiretroviral-naive patients with HIV and Tuberculosis infections in India: a multi-centre study. BMC infectious diseases, 2017, 12-11, Volume: 17, Issue:1 Topics: Adult; Alkynes; Antitubercular Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Female; HIV Infections; Humans; India; Kaplan-Meier Estimate; Male; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Tuberculosis; Viral Load	2017
Effect of patient genetics on etonogestrel pharmacokinetics when combined with efavirenz or nevirapine ART. The Journal of antimicrobial chemotherapy, 2019, 10-01, Volume: 74, Issue:10 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Cytochrome P-450 CYP2B6; Desogestrel; Drug Interactions; Female; Genotype; HIV Infections; Humans; Nevirapine; Polymorphism, Single Nucleotide; Young Adult	2019
Efficacy and safety of dihydroartemisinin-piperaquine for treatment of Plasmodium falciparum uncomplicated malaria in adult patients on antiretroviral therapy in Malawi and Mozambique: an open label non-randomized interventional trial. Malaria journal, 2019, Aug-20, Volume: 18, Issue:1 Topics: Adolescent; Adult; Alkynes; Anti-Retroviral Agents; Antimalarials; Artemisinins; Benzoxazines; Cyclopropanes; Drug Combinations; Female; Humans; Malaria, Falciparum; Malawi; Male; Middle Aged; Mozambique; Nevirapine; Plasmodium falciparum; Quinolines; Young Adult	2019
Pharmacogenetic interactions of rifapentine plus isoniazid with efavirenz or nevirapine. Pharmacogenetics and genomics, 2021, Volume: 31, Issue:1 Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Arylamine N-Acetyltransferase; Benzoxazines; Cyclopropanes; Drug Synergism; HIV Infections; Humans; Isoniazid; Male; Middle Aged; Nevirapine; Pharmacogenetics; Rifampin; Young Adult	2021
Lower Insulin Sensitivity in Newborns With In Utero HIV and Antiretroviral Exposure Who Are Uninfected in Botswana. The Journal of infectious diseases, 2022, 11-28, Volume: 226, Issue:11 Topics: Anti-HIV Agents; Anti-Retroviral Agents; Botswana; Female; HIV Infections; Humans; Infant; Infant, Newborn; Insulin Resistance; Nevirapine; Pregnancy; Zidovudine	2022

Other Studies

551 other study(ies) available for nevirapine and efavirenz

Article	Year
Urea-PETT compounds as a new class of HIV-1 reverse transcriptase inhibitors. 3. Synthesis and further structure-activity relationship studies of PETT analogues. Journal of medicinal chemistry, 1999, Oct-07, Volume: 42, Issue:20 Topics: Administration, Oral; Aminopyridines; Animals; Anti-HIV Agents; Biological Availability; Crystallography, X-Ray; Drug Resistance, Microbial; HIV-1; Injections, Intravenous; Male; Models, Molecular; Molecular Conformation; Rats; Reverse Transcriptase Inhibitors; Stereoisomerism; Structure-Activity Relationship; Urea	1999
Novel 2,2-dioxide-4,4-disubstituted-1,3-H-2,1,3-benzothiadiazines as non-nucleoside reverse transcriptase inhibitors. Bioorganic & medicinal chemistry letters, 2000, Jan-17, Volume: 10, Issue:2 Topics: Benzothiadiazines; HIV-1; Humans; Molecular Structure; Reverse Transcriptase Inhibitors	2000
Inhibition of clinically relevant mutant variants of HIV-1 by quinazolinone non-nucleoside reverse transcriptase inhibitors. Journal of medicinal chemistry, 2000, May-18, Volume: 43, Issue:10 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Blood Proteins; Cyclopropanes; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Structure; Mutation; Oxazines; Protein Binding; Quinazolines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Virus Replication	2000
2-Amino-6-arylsulfonylbenzonitriles as non-nucleoside reverse transcriptase inhibitors of HIV-1. Journal of medicinal chemistry, 2001, Jun-07, Volume: 44, Issue:12 Topics: Anti-HIV Agents; Binding Sites; Cell Line, Transformed; Crystallography, X-Ray; HIV Reverse Transcriptase; Human T-lymphotropic virus 1; Humans; Models, Molecular; Molecular Conformation; Molecular Structure; Nitriles; Protein Conformation; Structure-Activity Relationship; Sulfones	2001
Quinoxalinylethylpyridylthioureas (QXPTs) as potent non-nucleoside HIV-1 reverse transcriptase (RT) inhibitors. Further SAR studies and identification of a novel orally bioavailable hydrazine-based antiviral agent. Journal of medicinal chemistry, 2001, Feb-01, Volume: 44, Issue:3 Topics: Animals; Anti-HIV Agents; Biological Availability; Cell Line; Didanosine; Drug Synergism; HIV Reverse Transcriptase; HIV-1; Humans; Mice; Models, Molecular; Pyridines; Quinoxalines; Reverse Transcriptase Inhibitors; Stereoisomerism; Structure-Activity Relationship; Thiourea; Zidovudine	2001
Structure-based design, synthesis, and biological evaluation of conformationally restricted novel 2-alkylthio-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as non-nucleoside inhibitors of HIV-1 reverse transcriptase. Journal of medicinal chemistry, 2001, Aug-02, Volume: 44, Issue:16 Topics: Animals; Cell Line; Drug Design; HIV Reverse Transcriptase; HIV-1; Models, Molecular; Molecular Conformation; Mutation; Pyrimidines; Pyrimidinones; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2001
Evolution of anti-HIV drug candidates. Part 3: Diarylpyrimidine (DAPY) analogues. Bioorganic & medicinal chemistry letters, 2001, Sep-03, Volume: 11, Issue:17 Topics: Anti-HIV Agents; Drug Evaluation, Preclinical; HIV Reverse Transcriptase; HIV-1; Inhibitory Concentration 50; Mutation; Nitriles; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2001
Antiviral drug design: computational analyses of the effects of the L100I mutation for HIV-RT on the binding of NNRTIs. Bioorganic & medicinal chemistry letters, 2001, Nov-05, Volume: 11, Issue:21 Topics: Drug Design; HIV Reverse Transcriptase; Models, Molecular; Mutation; Reverse Transcriptase Inhibitors	2001
Prediction of activity for nonnucleoside inhibitors with HIV-1 reverse transcriptase based on Monte Carlo simulations. Journal of medicinal chemistry, 2002, Jul-04, Volume: 45, Issue:14 Topics: Alkynes; Anilides; Benzoxazines; Computer Simulation; Cyclopropanes; HIV Reverse Transcriptase; Hydrogen Bonding; Models, Molecular; Monte Carlo Method; Nevirapine; Oxazines; Protein Binding; Quinoxalines; Regression Analysis; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Uracil	2002
Synthesis of novel N-1 (allyloxymethyl) analogues of 6-benzyl-1-(ethoxymethyl)-5-isopropyluracil (MKC-442, emivirine) with improved activity against HIV-1 and its mutants. Journal of medicinal chemistry, 2002, Dec-19, Volume: 45, Issue:26 Topics: Anti-HIV Agents; Cell Line; HIV-1; Humans; Magnetic Resonance Spectroscopy; Mutation; Stereoisomerism; Structure-Activity Relationship; Uracil; Virus Replication	2002
Novel indolyl aryl sulfones active against HIV-1 carrying NNRTI resistance mutations: synthesis and SAR studies. Journal of medicinal chemistry, 2003, Jun-05, Volume: 46, Issue:12 Topics: Anti-HIV Agents; Cell Line; Drug Resistance, Viral; HIV-1; Humans; Indoles; Mutation; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Sulfones	2003
3-iodo-4-phenoxypyridinones (IOPY's), a new family of highly potent non-nucleoside inhibitors of HIV-1 reverse transcriptase. Bioorganic & medicinal chemistry letters, 2003, Dec-15, Volume: 13, Issue:24 Topics: HIV-1; Models, Molecular; Molecular Conformation; Pyridones; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2003
Computer-aided design, synthesis, and anti-HIV-1 activity in vitro of 2-alkylamino-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as novel potent non-nucleoside reverse transcriptase inhibitors, also active against the Y181C varia Journal of medicinal chemistry, 2004, Feb-12, Volume: 47, Issue:4 Topics: Cell Line; Computer Simulation; Drug Design; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Models, Molecular; Mutation; Pyrimidinones; Quantitative Structure-Activity Relationship; Reverse Transcriptase Inhibitors	2004
Novel benzophenones as non-nucleoside reverse transcriptase inhibitors of HIV-1. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Anti-HIV Agents; Benzophenones; Cell Line; Crystallography, X-Ray; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Inhibitory Concentration 50; Mutation; Protein Binding; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2004
Threshold interaction energy of NRTI's (2'-deoxy 3'-substituted nucleosidic analogs of reverse transcriptase inhibitors) to undergo competitive inhibition. Bioorganic & medicinal chemistry letters, 2004, May-17, Volume: 14, Issue:10 Topics: Anti-HIV Agents; Binding, Competitive; Inhibitory Concentration 50; Models, Molecular; Nucleosides; Protein Binding; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thermodynamics	2004
Roles of conformational and positional adaptability in structure-based design of TMC125-R165335 (etravirine) and related non-nucleoside reverse transcriptase inhibitors that are highly potent and effective against wild-type and drug-resistant HIV-1 varian Journal of medicinal chemistry, 2004, May-06, Volume: 47, Issue:10 Topics: Anti-HIV Agents; Crystallography, X-Ray; Drug Resistance, Viral; HIV Reverse Transcriptase; Models, Molecular; Mutation; Nitriles; Protein Conformation; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors	2004
5-Alkyl-2-[(aryl and alkyloxylcarbonylmethyl)thio]-6-(1-naphthylmethyl) pyrimidin-4(3H)-ones as an unique HIV reverse transcriptase inhibitors of S-DABO series. Bioorganic & medicinal chemistry letters, 2004, Jun-21, Volume: 14, Issue:12 Topics: Anti-HIV Agents; Cell Line; HIV Reverse Transcriptase; Humans; Pyrimidines; Pyrimidinones; Reverse Transcriptase Inhibitors	2004
Simple, short peptide derivatives of a sulfonylindolecarboxamide (L-737,126) active in vitro against HIV-1 wild type and variants carrying non-nucleoside reverse transcriptase inhibitor resistance mutations. Journal of medicinal chemistry, 2004, Jul-15, Volume: 47, Issue:15 Topics: Anti-HIV Agents; Cell Line; Drug Resistance, Viral; HIV-1; Humans; Indoles; Mutation; Reverse Transcriptase Inhibitors; Sulfones	2004
4-benzyl- and 4-benzoyl-3-dimethylaminopyridin-2(1H)-ones, a new family of potent anti-HIV agents: optimization and in vitro evaluation against clinically important HIV mutant strains. Journal of medicinal chemistry, 2004, Oct-21, Volume: 47, Issue:22 Topics: Alkynes; Aminopyridines; Anti-HIV Agents; Benzene Derivatives; Benzoates; Benzoxazines; Cell Line; Cyclopropanes; HIV-1; Humans; Mutagenesis, Site-Directed; Mutation; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Uracil	2004
Studies of nonnucleoside HIV-1 reverse transcriptase inhibitors. Part 1: Design and synthesis of thiazolidenebenzenesulfonamides. Bioorganic & medicinal chemistry, 2004, Dec-01, Volume: 12, Issue:23 Topics: Benzenesulfonates; Binding Sites; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Molecular Structure; Nevirapine; Protein Binding; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Sulfonamides; Thiazoles; Virus Replication	2004
Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 2. Journal of medicinal chemistry, 2004, Nov-18, Volume: 47, Issue:24 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Binding Sites; Cell Line; Crystallography, X-Ray; Cyclopropanes; Drug Design; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Molecular Structure; Mutation; Oxazines; Quinolones; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2004
Docking and 3-D QSAR studies on indolyl aryl sulfones. Binding mode exploration at the HIV-1 reverse transcriptase non-nucleoside binding site and design of highly active N-(2-hydroxyethyl)carboxamide and N-(2-hydroxyethyl)carbohydrazide derivatives. Journal of medicinal chemistry, 2005, Jan-13, Volume: 48, Issue:1 Topics: Binding Sites; Cells, Cultured; Drug Design; Drug Evaluation, Preclinical; HIV Reverse Transcriptase; Humans; Hydrazines; Microbial Sensitivity Tests; Models, Molecular; Nucleosides; Protein Conformation; Quantitative Structure-Activity Relationship; Reverse Transcriptase Inhibitors; Software; Sulfones	2005
4-Benzyl and 4-benzoyl-3-dimethylaminopyridin-2(1H)-ones: in vitro evaluation of new C-3-amino-substituted and C-5,6-alkyl-substituted analogues against clinically important HIV mutant strains. Journal of medicinal chemistry, 2005, Mar-24, Volume: 48, Issue:6 Topics: Anti-HIV Agents; Binding Sites; Combinatorial Chemistry Techniques; Crystallography, X-Ray; HIV Reverse Transcriptase; HIV-1; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Binding; Pyridines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2005
Synthesis of novel diarylpyrimidine analogues and their antiviral activity against human immunodeficiency virus type 1. Journal of medicinal chemistry, 2005, Mar-24, Volume: 48, Issue:6 Topics: Anti-HIV Agents; Cell Line; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Pyrimidines; Reverse Transcriptase Inhibitors; Stereoisomerism; Structure-Activity Relationship	2005
Hierarchical database screenings for HIV-1 reverse transcriptase using a pharmacophore model, rigid docking, solvation docking, and MM-PB/SA. Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7 Topics: Allosteric Site; Anti-HIV Agents; Crystallography, X-Ray; Databases, Factual; Drug Design; HIV Reverse Transcriptase; Models, Molecular; Molecular Conformation; Molecular Structure; Protein Binding; Quantitative Structure-Activity Relationship; Reverse Transcriptase Inhibitors; Statistics as Topic; Thermodynamics	2005
Novel 1-[2-(diarylmethoxy)ethyl]-2-methyl-5-nitroimidazoles as HIV-1 non-nucleoside reverse transcriptase inhibitors. A structure-activity relationship investigation. Journal of medicinal chemistry, 2005, Jun-30, Volume: 48, Issue:13 Topics: Animals; Binding Sites; Cell Line; Cell Survival; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Models, Molecular; Molecular Conformation; Nevirapine; Nitroimidazoles; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Virus Replication	2005
6-[1-(2,6-difluorophenyl)ethyl]pyrimidinones antagonize cell proliferation and induce cell differentiation by inhibiting (a nontelomeric) endogenous reverse transcriptase. Journal of medicinal chemistry, 2005, Nov-03, Volume: 48, Issue:22 Topics: Antineoplastic Agents; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Fluorobenzenes; Humans; Pyrimidinones; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Structure-Activity Relationship	2005
Specific targeting highly conserved residues in the HIV-1 reverse transcriptase primer grip region. Design, synthesis, and biological evaluation of novel, potent, and broad spectrum NNRTIs with antiviral activity. Journal of medicinal chemistry, 2005, Nov-17, Volume: 48, Issue:23 Topics: Amino Acid Sequence; Animals; Anti-HIV Agents; Binding Sites; Cells, Cultured; Conserved Sequence; Drug Design; Drug Resistance, Viral; Drug Synergism; HIV Reverse Transcriptase; HIV-1; Humans; Macrophages; Mice; Models, Molecular; Mutation; Oxazepines; Pyrroles; Reverse Transcriptase Inhibitors; Stereoisomerism; Structure-Activity Relationship; Virus Replication; Zidovudine	2005
Parallel solution-phase and microwave-assisted synthesis of new S-DABO derivatives endowed with subnanomolar anti-HIV-1 activity. Journal of medicinal chemistry, 2005, Dec-15, Volume: 48, Issue:25 Topics: Anti-HIV Agents; Cell Line; Drug Resistance, Multiple, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Microwaves; Models, Molecular; Mutation; Pyrimidines; Pyrimidinones; Reverse Transcriptase Inhibitors; Solutions; Structure-Activity Relationship	2005
Structure-activity relationship studies of novel benzophenones leading to the discovery of a potent, next generation HIV nonnucleoside reverse transcriptase inhibitor. Journal of medicinal chemistry, 2006, Jan-26, Volume: 49, Issue:2 Topics: Alkynes; Animals; Anti-HIV Agents; Benzophenones; Benzoxazines; Cell Line; Cyclopropanes; Dogs; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Macaca fascicularis; Male; Mutation; Nevirapine; Nitriles; Oxazines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Sulfonamides	2006
Design, synthesis, and biological evaluations of novel oxindoles as HIV-1 non-nucleoside reverse transcriptase inhibitors. Part 2. Bioorganic & medicinal chemistry letters, 2006, Apr-15, Volume: 16, Issue:8 Topics: Anti-HIV Agents; Drug Design; Drug Resistance, Viral; HIV-1; Indoles; Reverse Transcriptase Inhibitors; Stereoisomerism; Structure-Activity Relationship; Virus Replication	2006
Design, synthesis and biological evaluations of novel oxindoles as HIV-1 non-nucleoside reverse transcriptase inhibitors. Part I. Bioorganic & medicinal chemistry letters, 2006, Apr-15, Volume: 16, Issue:8 Topics: Anti-HIV Agents; Drug Resistance, Viral; HIV-1; Indoles; Reverse Transcriptase Inhibitors; Stereoisomerism; Structure-Activity Relationship; Virus Replication	2006
New HIV-1 reverse transcriptase inhibitors based on a tricyclic benzothiophene scaffold: synthesis, resolution, and inhibitory activity. Bioorganic & medicinal chemistry letters, 2006, Jun-01, Volume: 16, Issue:11 Topics: Circular Dichroism; Cyclization; HIV Reverse Transcriptase; Molecular Structure; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thiophenes	2006
Synthesis and biological investigation of S-aryl-S-DABO derivatives as HIV-1 inhibitors. Bioorganic & medicinal chemistry letters, 2006, Jul-01, Volume: 16, Issue:13 Topics: Anti-HIV Agents; Binding Sites; Cell Death; Cell Line; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Microwaves; Molecular Structure; Pyrimidines; Reverse Transcriptase Inhibitors; Stereoisomerism; Structure-Activity Relationship	2006
Synthesis and evaluation of N-aryl pyrrolidinones as novel anti-HIV-1 agents. Part 1. Bioorganic & medicinal chemistry letters, 2006, Jul-01, Volume: 16, Issue:13 Topics: Anti-HIV Agents; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Pyrrolidinones; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Virus Replication	2006
Design, molecular modeling, synthesis, and anti-HIV-1 activity of new indolyl aryl sulfones. Novel derivatives of the indole-2-carboxamide. Journal of medicinal chemistry, 2006, Jun-01, Volume: 49, Issue:11 Topics: Anti-HIV Agents; Cells, Cultured; Drug Design; Drug Resistance, Viral; HIV-1; Humans; Indoles; Lymphocytes; Macrophages; Models, Molecular; Pyrrolidinones; Quantitative Structure-Activity Relationship; Solubility; Sulfones	2006
Synthesis and biological evaluations of sulfanyltriazoles as novel HIV-1 non-nucleoside reverse transcriptase inhibitors. Bioorganic & medicinal chemistry letters, 2006, Aug-15, Volume: 16, Issue:16 Topics: Anti-HIV Agents; Chemistry, Pharmaceutical; Drug Design; Drug Resistance, Viral; Enzyme Inhibitors; HIV-1; Inhibitory Concentration 50; Models, Chemical; Models, Molecular; Mutation; Reverse Transcriptase Inhibitors; Sulfur Compounds; Temperature; Triazoles; Virus Replication	2006
Design, synthesis, and biological evaluations of novel quinolones as HIV-1 non-nucleoside reverse transcriptase inhibitors. Bioorganic & medicinal chemistry letters, 2006, Aug-15, Volume: 16, Issue:16 Topics: Binding Sites; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Models, Chemical; Models, Molecular; Mutation; Quinolones; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Virus Replication	2006
Optimization of pyrimidinyl- and triazinyl-amines as non-nucleoside inhibitors of HIV-1 reverse transcriptase. Bioorganic & medicinal chemistry letters, 2006, Nov-01, Volume: 16, Issue:21 Topics: Amines; HIV Reverse Transcriptase; HIV-1; Pyrimidines; Triazines	2006
4-Aminopyrimidines as novel HIV-1 inhibitors. Bioorganic & medicinal chemistry letters, 2007, Jan-01, Volume: 17, Issue:1 Topics: Anti-HIV Agents; HIV-1; Pyrimidines; Structure-Activity Relationship	2007
Development of a new methodology for screening of human immunodeficiency virus type 1 microbicides based on real-time PCR quantification. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:2 Topics: Alkynes; Benzoxazines; Biological Assay; Cell-Free System; Cyclopropanes; Female; HIV-1; Humans; Nevirapine; Reverse Transcriptase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Reverse Transcription; Sensitivity and Specificity; Virology	2007
A novel nonnucleoside analogue that inhibits human immunodeficiency virus type 1 isolates resistant to current nonnucleoside reverse transcriptase inhibitors. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:2 Topics: Administration, Oral; Alkynes; Animals; Anti-HIV Agents; Benzoxazines; Cell Line; Cyclopropanes; Dogs; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Mutation; Reverse Transcriptase Inhibitors; Triazoles	2007
Inhibition of MRP1/ABCC1, MRP2/ABCC2, and MRP3/ABCC3 by nucleoside, nucleotide, and non-nucleoside reverse transcriptase inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:3 Topics: Animals; Anti-HIV Agents; Cell Line; Dogs; Humans; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Reverse Transcriptase Inhibitors	2007
HIV-1 reverse transcriptase plus-strand initiation exhibits preferential sensitivity to non-nucleoside reverse transcriptase inhibitors in vitro. The Journal of biological chemistry, 2007, Mar-16, Volume: 282, Issue:11 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Benzoxazoles; Cyclopropanes; DNA; Dose-Response Relationship, Drug; Drug Resistance, Viral; Enzyme Inhibitors; HIV Reverse Transcriptase; In Vitro Techniques; Inhibitory Concentration 50; Ligands; Models, Genetic; Oxazines; Pyridones; Reverse Transcriptase Inhibitors; Stochastic Processes; Transcription, Genetic; Virus Replication	2007
Synthesis of novel diarylpyrimidine analogues of TMC278 and their antiviral activity against HIV-1 wild-type and mutant strains. European journal of medicinal chemistry, 2007, Volume: 42, Issue:5 Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Female; HIV-1; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Nitriles; Pyrimidines; Rats; Rats, Wistar; Reverse Transcriptase Inhibitors; Rilpivirine; Spectrophotometry, Ultraviolet	2007
Discovery of novel benzimidazolones as potent non-nucleoside reverse transcriptase inhibitors active against wild-type and mutant HIV-1 strains. Bioorganic & medicinal chemistry letters, 2007, Apr-01, Volume: 17, Issue:7 Topics: Acquired Immunodeficiency Syndrome; Alkynes; Anti-Retroviral Agents; Benzoxazines; Cell Line; Chemistry, Pharmaceutical; Cyclopropanes; Drug Design; Enzyme Inhibitors; HIV-1; Humans; Inhibitory Concentration 50; Models, Molecular; Molecular Conformation; Mutation; Nevirapine; Reverse Transcriptase Inhibitors	2007
Synthesis and biological evaluation of alkenyldiarylmethane HIV-1 non-nucleoside reverse transcriptase inhibitors that possess increased hydrolytic stability. Journal of medicinal chemistry, 2007, Oct-04, Volume: 50, Issue:20 Topics: Alkenes; Animals; Anti-HIV Agents; Benzoates; Cytopathogenic Effect, Viral; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Hydrolysis; Mutation; Nitriles; Oxadiazoles; Oxazoles; Rats; Reverse Transcriptase Inhibitors; Stereoisomerism; Structure-Activity Relationship; Tetrazoles	2007
Indolyl aryl sulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors: role of two halogen atoms at the indole ring in developing new analogues with improved antiviral activity. Journal of medicinal chemistry, 2007, Oct-04, Volume: 50, Issue:20 Topics: Cell Line; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; In Vitro Techniques; Indoles; Lymphocytes; Macrophages; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Sulfones	2007
Synthesis and biological properties of novel 2-aminopyrimidin-4(3H)-ones highly potent against HIV-1 mutant strains. Journal of medicinal chemistry, 2007, Nov-01, Volume: 50, Issue:22 Topics: Anti-HIV Agents; Cell Line; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Mutation; Protein Binding; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2007
From docking false-positive to active anti-HIV agent. Journal of medicinal chemistry, 2007, Nov-01, Volume: 50, Issue:22 Topics: Anti-HIV Agents; Cell Line; Databases, Factual; HIV Reverse Transcriptase; HIV-1; Humans; Ligands; Models, Molecular; Molecular Conformation; Oxadiazoles; Quantitative Structure-Activity Relationship; Reverse Transcriptase Inhibitors; Thermodynamics	2007
Dihydro-alkylthio-benzyl-oxopyrimidines as inhibitors of reverse transcriptase: synthesis and rationalization of the biological data on both wild-type enzyme and relevant clinical mutants. Journal of medicinal chemistry, 2007, Dec-27, Volume: 50, Issue:26 Topics: Anti-HIV Agents; Cell Line; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Mutation; Pyrimidines; Quantitative Structure-Activity Relationship; Recombinant Proteins; Reverse Transcriptase Inhibitors; Sulfides	2007
Novel N1-substituted 1,3-dihydro-2H-benzimidazol-2-ones as potent non-nucleoside reverse transcriptase inhibitors. Bioorganic & medicinal chemistry, 2008, Aug-01, Volume: 16, Issue:15 Topics: Anti-HIV Agents; Benzimidazoles; Cell Line; HIV-1; Humans; Models, Molecular; Molecular Structure; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Virus Replication	2008
5-Alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a series of anti-HIV-1 agents of the dihydro-alkoxy-benzyl-oxopyrimidine family with peculiar structure-activity relationship profile. Journal of medicinal chemistry, 2008, Aug-14, Volume: 51, Issue:15 Topics: Alkylation; Anti-HIV Agents; Benzene; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; HIV-1; Hydrogen; Models, Molecular; Molecular Structure; Mutation; Oxygen; Protein Binding; Pyrimidinones; RNA-Directed DNA Polymerase; Structure-Activity Relationship; Sulfur Compounds	2008
Structural basis for the improved drug resistance profile of new generation benzophenone non-nucleoside HIV-1 reverse transcriptase inhibitors. Journal of medicinal chemistry, 2008, Aug-28, Volume: 51, Issue:16 Topics: Alkynes; Amino Acid Substitution; Benzophenones; Benzoxazines; Crystallography, X-Ray; Cyclopropanes; Drug Design; Drug Resistance, Viral; HIV Reverse Transcriptase; Models, Molecular; Nevirapine; Nitriles; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Sulfonamides	2008
1,2,3-Thiadiazole thioacetanilides as a novel class of potent HIV-1 non-nucleoside reverse transcriptase inhibitors. Bioorganic & medicinal chemistry letters, 2008, Oct-15, Volume: 18, Issue:20 Topics: Anti-HIV Agents; Biological Assay; Cell Line; Chemistry, Pharmaceutical; Drug Design; Drug Evaluation, Preclinical; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Models, Chemical; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thiadiazoles; Virus Replication	2008
Towards novel S-DABOC inhibitors: synthesis, biological investigation, and molecular modeling studies. Bioorganic & medicinal chemistry letters, 2008, Nov-01, Volume: 18, Issue:21 Topics: Anti-HIV Agents; Cytosine; HIV-1; Microbial Sensitivity Tests; Models, Molecular	2008
Inhibition of human immunodeficiency virus type 1 infection by the candidate microbicide dapivirine, a nonnucleoside reverse transcriptase inhibitor. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:2 Topics: Anti-HIV Agents; Cells, Cultured; Cervix Uteri; Dose-Response Relationship, Drug; Female; HIV Infections; HIV-1; Humans; Luciferases; Macrophages; Organ Culture Techniques; Pyrimidines; Reverse Transcriptase Inhibitors; T-Lymphocytes	2009
Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks. Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2 Topics: Anti-Infective Agents; Antiviral Agents; Artificial Intelligence; Computer Simulation; Drug Evaluation, Preclinical; Molecular Structure; Quantitative Structure-Activity Relationship	2009
Discovery of chiral cyclopropyl dihydro-alkylthio-benzyl-oxopyrimidine (S-DABO) derivatives as potent HIV-1 reverse transcriptase inhibitors with high activity against clinically relevant mutants. Journal of medicinal chemistry, 2009, Feb-12, Volume: 52, Issue:3 Topics: Cell Line, Tumor; Computer Simulation; Drug Design; Drug Resistance, Viral; HIV Reverse Transcriptase; Humans; Kinetics; Models, Molecular; Mutation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrimidinones; Reverse Transcriptase Inhibitors; Stereoisomerism; Sulfides; Surface Plasmon Resonance	2009
Specific targeting of highly conserved residues in the HIV-1 reverse transcriptase primer grip region. 2. Stereoselective interaction to overcome the effects of drug resistant mutations. Journal of medicinal chemistry, 2009, Feb-26, Volume: 52, Issue:4 Topics: Anti-HIV Agents; Conserved Sequence; Drug Resistance; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Mutation; Reverse Transcriptase Inhibitors; Stereoisomerism; Structure-Activity Relationship	2009
Human immunodeficiency virus type 1 isolates with the reverse transcriptase (RT) mutation Q145M retain nucleoside and nonnucleoside RT inhibitor susceptibility. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5 Topics: Amino Acid Sequence; Anti-HIV Agents; Drug Resistance, Viral; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Nucleosides; Phenotype; Reverse Transcriptase Inhibitors	2009
Indolylarylsulfones bearing natural and unnatural amino acids. Discovery of potent inhibitors of HIV-1 non-nucleoside wild type and resistant mutant strains reverse transcriptase and coxsackie B4 virus. Journal of medicinal chemistry, 2009, Apr-09, Volume: 52, Issue:7 Topics: Amino Acids; Animals; Anti-HIV Agents; Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Cell Proliferation; Cytostatic Agents; Drug Resistance, Viral; Enterovirus B, Human; HIV Reverse Transcriptase; HIV-1; Humans; Hydrophobic and Hydrophilic Interactions; Indoles; Lymphocytes; Mice; Models, Molecular; Molecular Conformation; Mutation; Protein Binding; Reverse Transcriptase Inhibitors; Stereoisomerism; Structure-Activity Relationship; Sulfones; Virus Replication	2009
Antiviral activity of MK-4965, a novel nonnucleoside reverse transcriptase inhibitor. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cell Line; Cyclopropanes; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Nevirapine; Nitriles; Pyrazoles; Pyridazines; Pyridines; Pyrimidines; Reverse Transcriptase Inhibitors	2009
New pyridinone derivatives as potent HIV-1 nonnucleoside reverse transcriptase inhibitors. Journal of medicinal chemistry, 2009, Jun-25, Volume: 52, Issue:12 Topics: Anti-HIV Agents; Binding Sites; Cell Line; Cell Survival; Cell Transformation, Viral; Computer Simulation; Crystallography, X-Ray; HIV; HIV Reverse Transcriptase; Humans; Microbial Sensitivity Tests; Models, Chemical; Models, Molecular; Molecular Structure; Pyridones; Reverse Transcriptase Inhibitors; Stereoisomerism; Structure-Activity Relationship	2009
Design, synthesis, and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents. Bioorganic & medicinal chemistry, 2009, Aug-15, Volume: 17, Issue:16 Topics: Anti-HIV Agents; Benzimidazoles; Cell Line; Drug Design; HIV Reverse Transcriptase; Humans; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2009
Synthesis and anti-HIV activity evaluation of 2-(4-(naphthalen-2-yl)-1,2,3-thiadiazol-5-ylthio)-N-acetamides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Acetamides; Anti-HIV Agents; Cell Line; HIV Infections; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Models, Molecular; Protein Binding; Structure-Activity Relationship	2009
Synthesis and biological evaluation of imidazole thioacetanilides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors. Bioorganic & medicinal chemistry, 2009, Aug-15, Volume: 17, Issue:16 Topics: Acetanilides; Anti-HIV Agents; Binding Sites; Computer Simulation; HIV Reverse Transcriptase; Humans; Imidazoles; Structure-Activity Relationship	2009
Synthesis and biological evaluation of C-5 methyl substituted 4-arylthio and 4-aryloxy-3-Iodopyridin-2(1H)-one type anti-HIV agents. Journal of medicinal chemistry, 2009, Dec-10, Volume: 52, Issue:23 Topics: Anti-HIV Agents; Cell Line; HIV; HIV Reverse Transcriptase; Humans; Inhibitory Concentration 50; Iodopyridones; Mutation; Small Molecule Libraries	2009
Human immunodeficiency virus type 1 recombinant reverse transcriptase enzymes containing the G190A and Y181C resistance mutations remain sensitive to etravirine. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:11 Topics: Anti-HIV Agents; Drug Resistance, Viral; HIV Reverse Transcriptase; Microbial Sensitivity Tests; Mutation; Nitriles; Pyridazines; Pyrimidines; Recombinant Proteins; Reverse Transcriptase Inhibitors	2009
Activity and molecular modeling of a new small molecule active against NNRTI-resistant HIV-1 mutants. European journal of medicinal chemistry, 2009, Volume: 44, Issue:12 Topics: Anti-HIV Agents; Cyclic N-Oxides; Dose-Response Relationship, Drug; Drug Resistance, Viral; HIV-1; Humans; Inhibitory Concentration 50; Models, Molecular; Molecular Structure; Mutation; Quinolines; Reverse Transcriptase Inhibitors; Thermodynamics	2009
TMC278, a next-generation nonnucleoside reverse transcriptase inhibitor (NNRTI), active against wild-type and NNRTI-resistant HIV-1. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:2 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cell Line; Cells, Cultured; Cyclopropanes; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Molecular Structure; Nevirapine; Nitriles; Pyridazines; Pyrimidines; Rilpivirine	2010
Resistance-associated mutations to etravirine (TMC-125) in antiretroviral-naïve patients infected with non-B HIV-1 subtypes. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:2 Topics: Anti-HIV Agents; Drug Resistance, Viral; Genotype; HIV Infections; HIV-1; Humans; Mutation; Nitriles; Phylogeny; Pyridazines; Pyrimidines	2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Novel 1,3-dihydro-benzimidazol-2-ones and their analogues as potent non-nucleoside HIV-1 reverse transcriptase inhibitors. Bioorganic & medicinal chemistry, 2010, Feb-15, Volume: 18, Issue:4 Topics: Benzimidazoles; Cell Line; HIV Reverse Transcriptase; HIV-1; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Virus Replication	2010
Combination of V106I and V179D polymorphic mutations in human immunodeficiency virus type 1 reverse transcriptase confers resistance to efavirenz and nevirapine but not etravirine. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:4 Topics: Alkynes; Amino Acid Substitution; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; Genes, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; In Vitro Techniques; Models, Molecular; Mutation, Missense; Nevirapine; Nitriles; Pyridazines; Pyrimidines; Recombination, Genetic; Virus Replication	2010
Combinations of mutations in the connection domain of human immunodeficiency virus type 1 reverse transcriptase: assessing the impact on nucleoside and nonnucleoside reverse transcriptase inhibitor resistance. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5 Topics: Amino Acid Substitution; Anti-HIV Agents; Drug Resistance, Viral; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Mutagenesis, Site-Directed; Mutation; Nucleosides; Phenotype; pol Gene Products, Human Immunodeficiency Virus; Protein Structure, Tertiary; Reverse Transcriptase Inhibitors; Virus Replication	2010
Eastern extension of azoles as non-nucleoside inhibitors of HIV-1 reverse transcriptase; cyano group alternatives. Bioorganic & medicinal chemistry letters, 2010, Apr-15, Volume: 20, Issue:8 Topics: Azoles; HIV-1; Models, Molecular; Reverse Transcriptase Inhibitors	2010
Synthesis and biological evaluation of 4-(hydroxyimino)arylmethyl diarylpyrimidine analogues as potential non-nucleoside reverse transcriptase inhibitors against HIV. Bioorganic & medicinal chemistry, 2010, Apr-01, Volume: 18, Issue:7 Topics: Anti-HIV Agents; Cell Line; Cell Survival; HIV-1; HIV-2; Humans; Indicators and Reagents; Pyrimidines; Reverse Transcriptase Inhibitors; Stereoisomerism; Structure-Activity Relationship	2010
The M230L nonnucleoside reverse transcriptase inhibitor resistance mutation in HIV-1 reverse transcriptase impairs enzymatic function and viral replicative capacity. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:6 Topics: Anti-HIV Agents; Base Sequence; Cell Line; DNA, Viral; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Recombinant Proteins; Reverse Transcriptase Inhibitors; Virus Replication	2010
Synthesis and anti-HIV activity of 2-naphthyl substituted DAPY analogues as non-nucleoside reverse transcriptase inhibitors. Bioorganic & medicinal chemistry, 2010, Jul-01, Volume: 18, Issue:13 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Binding Sites; Cell Line; Computer Simulation; Cyclopropanes; HIV Reverse Transcriptase; HIV-1; Humans; Naphthols; Pyrimidines; Reverse Transcriptase Inhibitors	2010
Hybrid diarylbenzopyrimidine non-nucleoside reverse transcriptase inhibitors as promising new leads for improved anti-HIV-1 chemotherapy. Bioorganic & medicinal chemistry, 2010, Jul-15, Volume: 18, Issue:14 Topics: Anti-HIV Agents; Cell Line; Cell Survival; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Nitriles; Protein Binding; Pyridazines; Pyrimidines; Quinazolines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2010
Lersivirine, a nonnucleoside reverse transcriptase inhibitor with activity against drug-resistant human immunodeficiency virus type 1. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:10 Topics: Cell Line; Cell Line, Tumor; Crystallography, X-Ray; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitriles; Pyrazoles; Reverse Transcriptase Inhibitors	2010
Discovery and SAR of a series of 4,6-diamino-1,3,5-triazin-2-ol as novel non-nucleoside reverse transcriptase inhibitors of HIV-1. Bioorganic & medicinal chemistry letters, 2010, Nov-15, Volume: 20, Issue:22 Topics: Animals; Drug Discovery; Models, Molecular; Rats; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Triazines	2010
Identification and characterization of persistent intracellular human immunodeficiency virus type 1 integrase strand transfer inhibitor activity. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:1 Topics: Adenine; Anti-HIV Agents; Cell Line; HeLa Cells; HIV-1; Humans; Integrase Inhibitors; Organophosphonates; Pyrrolidinones; Quinolones; Raltegravir Potassium; Tenofovir; Zidovudine	2011
Interaction potential of etravirine with drug transporters assessed in vitro. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:3 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Blotting, Western; Cell Line; Cell Line, Tumor; Cell Proliferation; Dogs; Humans; Neoplasm Proteins; Nitriles; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors	2011
Indolylarylsulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors: new cyclic substituents at indole-2-carboxamide. Journal of medicinal chemistry, 2011, Mar-24, Volume: 54, Issue:6 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cells, Cultured; Cyclopropanes; HIV Reverse Transcriptase; HIV-1; Humans; Indoles; Leukocytes, Mononuclear; Models, Molecular; Molecular Conformation; Mutation; Nevirapine; Nitriles; Protein Binding; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Sulfones	2011
Diarylpyrimidine-dihydrobenzyloxopyrimidine hybrids: new, wide-spectrum anti-HIV-1 agents active at (sub)-nanomolar level. Journal of medicinal chemistry, 2011, Apr-28, Volume: 54, Issue:8 Topics: Anti-HIV Agents; HIV-1; Pyrimidines	2011
Synthesis and biological evaluation of novel 5-alkyl-2-arylthio-6-((3,4-dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-ones as potent non-nucleoside HIV-1 reverse transcriptase inhibitors. Bioorganic & medicinal chemistry, 2011, Jul-15, Volume: 19, Issue:14 Topics: Anti-HIV Agents; Cell Line, Tumor; Crystallography, X-Ray; Dose-Response Relationship, Drug; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Pyrimidinones; Reverse Transcriptase Inhibitors; Stereoisomerism; Structure-Activity Relationship; Virus Replication	2011
Modulation of cell differentiation, proliferation, and tumor growth by dihydrobenzyloxopyrimidine non-nucleoside reverse transcriptase inhibitors. Journal of medicinal chemistry, 2011, Aug-25, Volume: 54, Issue:16 Topics: Animals; Apoptosis; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Fluorescent Antibody Technique, Indirect; Humans; Melanoma; Mice; Mice, Nude; Microscopy, Confocal; Molecular Structure; Pyrimidinones; Reverse Transcriptase Inhibitors; Tumor Burden; Xenograft Model Antitumor Assays	2011
Synthesis and structure-activity relationship of novel diarylpyrimidines with hydromethyl linker (CH(OH)-DAPYs) as HIV-1 NNRTIs. Bioorganic & medicinal chemistry, 2011, Sep-01, Volume: 19, Issue:17 Topics: Aniline Compounds; Cell Line; Chlorine; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2011
Arylazolylthioacetanilide. Part 8: Design, synthesis and biological evaluation of novel 2-(2-(2,4-dichlorophenyl)-2H-1,2,4-triazol-3-ylthio)-N-arylacetamides as potent HIV-1 inhibitors. European journal of medicinal chemistry, 2011, Volume: 46, Issue:10 Topics: Acetamides; Anti-HIV Agents; Cell Line; HIV Infections; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Triazoles; Virus Replication	2011
1-[2-(2-Benzoyl- and 2-benzylphenoxy)ethyl]uracils as potent anti-HIV-1 agents. Bioorganic & medicinal chemistry, 2011, Oct-01, Volume: 19, Issue:19 Topics: Amino Acid Substitution; Benzophenones; Cell Line; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Uracil	2011
Design, synthesis and biological evaluation of cycloalkyl arylpyrimidines (CAPYs) as HIV-1 NNRTIs. Bioorganic & medicinal chemistry, 2011, Dec-01, Volume: 19, Issue:23 Topics: Anti-HIV Agents; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2011
Computationally-guided optimization of a docking hit to yield catechol diethers as potent anti-HIV agents. Journal of medicinal chemistry, 2011, Dec-22, Volume: 54, Issue:24 Topics: Anti-HIV Agents; Catechols; Computer Simulation; Ethers; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Molecular Structure; Protein Binding; Quantitative Structure-Activity Relationship; Reverse Transcriptase Inhibitors; Stereoisomerism; T-Lymphocytes	2011
Synthesis and biological evaluation of piperidine-substituted triazine derivatives as HIV-1 non-nucleoside reverse transcriptase inhibitors. European journal of medicinal chemistry, 2012, Volume: 51 Topics: Anti-HIV Agents; Cell Line; Chemistry Techniques, Synthetic; HIV Reverse Transcriptase; HIV-1; Inhibitory Concentration 50; Piperidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Triazines	2012
2-(Alkyl/aryl)amino-6-benzylpyrimidin-4(3H)-ones as inhibitors of wild-type and mutant HIV-1: enantioselectivity studies. Journal of medicinal chemistry, 2012, Apr-12, Volume: 55, Issue:7 Topics: Anti-HIV Agents; Benzene Derivatives; Cell Line; Enzyme Assays; HIV Reverse Transcriptase; HIV-1; Humans; Kinetics; Models, Molecular; Mutation; Pyrimidinones; Stereoisomerism; Structure-Activity Relationship	2012
Chiral resolution, absolute configuration assignment and biological activity of racemic diarylpyrimidine CH(OH)-DAPY as potent nonnucleoside HIV-1 reverse transcriptase inhibitors. European journal of medicinal chemistry, 2012, Volume: 53 Topics: HIV Reverse Transcriptase; HIV-1; HIV-2; Models, Molecular; Protein Conformation; Pyrimidines; Reverse Transcriptase Inhibitors; Stereoisomerism	2012
Design, synthesis, anti-HIV evaluation and molecular modeling of piperidine-linked amino-triazine derivatives as potent non-nucleoside reverse transcriptase inhibitors. Bioorganic & medicinal chemistry, 2012, Jun-15, Volume: 20, Issue:12 Topics: Amines; Anti-HIV Agents; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Design; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Piperidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Triazines	2012
Diverse combinatorial design, synthesis and in vitro evaluation of new HEPT analogues as potential non-nucleoside HIV-1 reverse transcription inhibitors. European journal of medicinal chemistry, 2012, Volume: 54 Topics: Cell Line; Chemistry Techniques, Synthetic; Combinatorial Chemistry Techniques; Drug Design; HIV Reverse Transcriptase; HIV-1; Reverse Transcriptase Inhibitors; Thymine	2012
New nitrogen containing substituents at the indole-2-carboxamide yield high potent and broad spectrum indolylarylsulfone HIV-1 non-nucleoside reverse transcriptase inhibitors. Journal of medicinal chemistry, 2012, Jul-26, Volume: 55, Issue:14 Topics: Cell Line; HIV Reverse Transcriptase; HIV-1; Indoles; Mutation; Nitrogen; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Sulfones	2012
Arylazolyl(azinyl)thioacetanilides. Part 10: design, synthesis and biological evaluation of novel substituted imidazopyridinylthioacetanilides as potent HIV-1 inhibitors. Bioorganic & medicinal chemistry, 2012, Sep-15, Volume: 20, Issue:18 Topics: Acetanilides; Anti-HIV Agents; Cell Line; Dose-Response Relationship, Drug; Drug Design; HIV-1; Humans; Imidazoles; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Virus Replication	2012
Structure-based bioisosterism design, synthesis and biological evaluation of novel 1,2,4-triazin-6-ylthioacetamides as potent HIV-1 NNRTIs. Bioorganic & medicinal chemistry letters, 2012, Dec-01, Volume: 22, Issue:23 Topics: Binding Sites; Cell Line; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Docking Simulation; Protein Structure, Tertiary; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thioglycolates; Triazines	2012
Discovery of novel 2-(3-(2-chlorophenyl)pyrazin-2-ylthio)-N-arylacetamides as potent HIV-1 inhibitors using a structure-based bioisosterism approach. Bioorganic & medicinal chemistry, 2012, Dec-01, Volume: 20, Issue:23 Topics: Anti-HIV Agents; Drug Design; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Structure-Activity Relationship; Thioacetamide	2012
Optimization of benzyloxazoles as non-nucleoside inhibitors of HIV-1 reverse transcriptase to enhance Y181C potency. Bioorganic & medicinal chemistry letters, 2013, Feb-15, Volume: 23, Issue:4 Topics: Anti-HIV Agents; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2013
N1,N3-disubstituted uracils as nonnucleoside inhibitors of HIV-1 reverse transcriptase. Bioorganic & medicinal chemistry, 2013, Mar-01, Volume: 21, Issue:5 Topics: Binding Sites; Cell Line; Cinnamates; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Docking Simulation; Mutation; Protein Structure, Tertiary; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Uracil	2013
Synthesis and biological evaluation of phosphonate analogues of nevirapine. Bioorganic & medicinal chemistry letters, 2013, Mar-01, Volume: 23, Issue:5 Topics: HIV Infections; HIV-1; Humans; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2013
Synthesis and biological evaluation of pyridazine derivatives as novel HIV-1 NNRTIs. Bioorganic & medicinal chemistry, 2013, Apr-01, Volume: 21, Issue:7 Topics: Cell Line; Delavirdine; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Nevirapine; Pyridazines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2013
Molecular design, synthesis and biological evaluation of BP-O-DAPY and O-DAPY derivatives as non-nucleoside HIV-1 reverse transcriptase inhibitors. European journal of medicinal chemistry, 2013, Volume: 65 Topics: Anti-HIV Agents; Benzophenones; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Design; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2013
Extension into the entrance channel of HIV-1 reverse transcriptase--crystallography and enhanced solubility. Bioorganic & medicinal chemistry letters, 2013, Sep-15, Volume: 23, Issue:18 Topics: Anti-HIV Agents; Crystallography, X-Ray; Dose-Response Relationship, Drug; Enzyme Inhibitors; HIV Reverse Transcriptase; HIV-1; Models, Molecular; Molecular Structure; Pyrimidines; Solubility; Structure-Activity Relationship	2013
Optimization of diarylazines as anti-HIV agents with dramatically enhanced solubility. Bioorganic & medicinal chemistry letters, 2013, Sep-15, Volume: 23, Issue:18 Topics: Anti-HIV Agents; Cell Line, Transformed; Cell Proliferation; Dose-Response Relationship, Drug; HIV-1; Humans; Hydrazines; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Solubility; Structure-Activity Relationship	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Towards new C6-rigid S-DABO HIV-1 reverse transcriptase inhibitors: synthesis, biological investigation and molecular modeling studies. Bioorganic & medicinal chemistry, 2013, Nov-01, Volume: 21, Issue:21 Topics: Binding Sites; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Docking Simulation; Protein Binding; Protein Structure, Tertiary; Pyrimidines; Pyrimidinones; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2013
Design, synthesis and biological evaluation of 3-benzyloxy-linked pyrimidinylphenylamine derivatives as potent HIV-1 NNRTIs. Bioorganic & medicinal chemistry, 2013, Dec-01, Volume: 21, Issue:23 Topics: Anti-HIV Agents; Cell Line; Drug Design; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Docking Simulation; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2013
Novel piperidinylamino-diarylpyrimidine derivatives with dual structural conformations as potent HIV-1 non-nucleoside reverse transcriptase inhibitors. Bioorganic & medicinal chemistry letters, 2013, Dec-15, Volume: 23, Issue:24 Topics: Binding Sites; Drug Resistance, Viral; Enzyme Activation; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Docking Simulation; Protein Binding; Protein Structure, Tertiary; Pyrimidines; Reverse Transcriptase Inhibitors	2013
Design, synthesis and preliminary SAR studies of novel N-arylmethyl substituted piperidine-linked aniline derivatives as potent HIV-1 NNRTIs. Bioorganic & medicinal chemistry, 2014, Jan-01, Volume: 22, Issue:1 Topics: Aniline Compounds; Anti-HIV Agents; Drug Design; HIV-1; Humans; Models, Molecular; Piperidines; Structure-Activity Relationship	2014
Phenylspirodrimanes with anti-HIV activity from the sponge-derived fungus Stachybotrys chartarum MXH-X73. Journal of natural products, 2013, Dec-27, Volume: 76, Issue:12 Topics: Animals; Anti-HIV Agents; HIV-1; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Polycyclic Sesquiterpenes; Porifera; Reverse Transcriptase Inhibitors; Sesquiterpenes; Spiro Compounds; Stachybotrys; Structure-Activity Relationship	2013
Design and synthesis of N₁-aryl-benzimidazoles 2-substituted as novel HIV-1 non-nucleoside reverse transcriptase inhibitors. Bioorganic & medicinal chemistry, 2014, Feb-15, Volume: 22, Issue:4 Topics: Benzimidazoles; Binding Sites; Catalytic Domain; Cell Line; Drug Design; Enzyme Activation; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Docking Simulation; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Virus Replication	2014
Discovery of nitropyridine derivatives as potent HIV-1 non-nucleoside reverse transcriptase inhibitors via a structure-based core refining approach. European journal of medicinal chemistry, 2014, Apr-09, Volume: 76 Topics: Cell Line; Drug Discovery; HIV Reverse Transcriptase; HIV-1; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Pyridines; Reverse Transcriptase Inhibitors; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Virus Replication	2014
Structural modifications of CH(OH)-DAPYs as new HIV-1 non-nucleoside reverse transcriptase inhibitors. Bioorganic & medicinal chemistry, 2014, Apr-15, Volume: 22, Issue:8 Topics: Binding Sites; Cell Line; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Docking Simulation; Protein Structure, Tertiary; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2014
New indolylarylsulfones as highly potent and broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitors. European journal of medicinal chemistry, 2014, Jun-10, Volume: 80 Topics: Cell Line; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Indoles; Inhibitory Concentration 50; Models, Molecular; Protein Conformation; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Sulfones	2014
Synthesis and biological evaluation of CHX-DAPYs as HIV-1 non-nucleoside reverse transcriptase inhibitors. Bioorganic & medicinal chemistry, 2014, Jun-15, Volume: 22, Issue:12 Topics: Anti-HIV Agents; Benzamides; Cell Survival; Cells, Cultured; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Molecular Docking Simulation; Molecular Structure; Nitriles; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Tumor Cells, Cultured; Virus Replication	2014
Synthesis of novel fluoro analogues of MKC442 as microbicides. Journal of medicinal chemistry, 2014, Jun-26, Volume: 57, Issue:12 Topics: Anti-HIV Agents; Cell Line; Drug Resistance, Viral; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Pyrimidinones; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Uracil	2014
Exploring the role of 2-chloro-6-fluoro substitution in 2-alkylthio-6-benzyl-5-alkylpyrimidin-4(3H)-ones: effects in HIV-1-infected cells and in HIV-1 reverse transcriptase enzymes. Journal of medicinal chemistry, 2014, Jun-26, Volume: 57, Issue:12 Topics: Anti-HIV Agents; Cell Line; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Mutation; Pyrimidinones; Reverse Transcriptase Inhibitors; Stereoisomerism; Structure-Activity Relationship	2014
Design and synthesis of a new series of modified CH-diarylpyrimidines as drug-resistant HIV non-nucleoside reverse transcriptase inhibitors. European journal of medicinal chemistry, 2014, Jul-23, Volume: 82 Topics: Anti-HIV Agents; Dose-Response Relationship, Drug; Drug Design; HIV Reverse Transcriptase; HIV-1; HIV-2; Microbial Sensitivity Tests; Molecular Structure; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2014
2,4,5-Trisubstituted thiazole derivatives: a novel and potent class of non-nucleoside inhibitors of wild type and mutant HIV-1 reverse transcriptase. European journal of medicinal chemistry, 2014, Oct-06, Volume: 85 Topics: Drug Design; Drug Resistance, Viral; HEK293 Cells; HIV Reverse Transcriptase; HIV-1; Humans; Inhibitory Concentration 50; Models, Molecular; Mutation; Protein Conformation; Quantitative Structure-Activity Relationship; Reverse Transcriptase Inhibitors; Thiazoles	2014
Arylazolyl(azinyl)thioacetanilides. Part 16: Structure-based bioisosterism design, synthesis and biological evaluation of novel pyrimidinylthioacetanilides as potent HIV-1 inhibitors. Bioorganic & medicinal chemistry, 2014, Oct-01, Volume: 22, Issue:19 Topics: Acetanilides; Anti-HIV Agents; Dose-Response Relationship, Drug; Drug Design; HIV-1; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Pyrimidines; Structure-Activity Relationship; Virus Replication	2014
From human immunodeficiency virus non-nucleoside reverse transcriptase inhibitors to potent and selective antitrypanosomal compounds. Bioorganic & medicinal chemistry, 2014, Oct-01, Volume: 22, Issue:19 Topics: Anti-HIV Agents; Cell Line; Cell Survival; Dose-Response Relationship, Drug; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Parasitic Sensitivity Tests; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense	2014
Design, synthesis and anti-HIV evaluation of novel diarylnicotinamide derivatives (DANAs) targeting the entrance channel of the NNRTI binding pocket through structure-guided molecular hybridization. European journal of medicinal chemistry, 2014, Nov-24, Volume: 87 Topics: Anti-HIV Agents; Catalytic Domain; Dose-Response Relationship, Drug; Drug Design; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Molecular Structure; Niacinamide; Protein Conformation; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Tumor Cells, Cultured	2014
Picomolar Inhibitors of HIV-1 Reverse Transcriptase: Design and Crystallography of Naphthyl Phenyl Ethers. ACS medicinal chemistry letters, 2014, Nov-13, Volume: 5, Issue:11 Topics:	2014
Indolylarylsulfones carrying a heterocyclic tail as very potent and broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitors. Journal of medicinal chemistry, 2014, Dec-11, Volume: 57, Issue:23 Topics: Anti-HIV Agents; HIV-1; Indoles; Inhibitory Concentration 50; Molecular Docking Simulation; Reverse Transcriptase Inhibitors; Stereoisomerism; Structure-Activity Relationship; Sulfones	2014
Synthesis and biological evaluation of DAPY-DPEs hybrids as non-nucleoside inhibitors of HIV-1 reverse transcriptase. Bioorganic & medicinal chemistry, 2015, Feb-01, Volume: 23, Issue:3 Topics: Anti-HIV Agents; Binding Sites; Cell Line; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2015
Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 3: optimization of [1,2,4]triazolo[1,5-a]pyrimidine core via structure-based and physicochemical property-driven approaches. European journal of medicinal chemistry, 2015, Mar-06, Volume: 92 Topics: Anti-HIV Agents; Cell Line, Tumor; Dose-Response Relationship, Drug; Heterocyclic Compounds; Heterocyclic Compounds, 2-Ring; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Nitrogen; Reverse Transcriptase Inhibitors; Solubility; Structure-Activity Relationship; Sulfones	2015
Scaffold hopping: exploration of acetanilide-containing uracil analogues as potential NNRTIs. Bioorganic & medicinal chemistry, 2015, Mar-01, Volume: 23, Issue:5 Topics: Acetanilides; Anti-HIV Agents; Cell Line; Drug Evaluation, Preclinical; Humans; Models, Molecular; Reverse Transcriptase Inhibitors; Uracil	2015
Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 4: design, synthesis and biological evaluation of novel imidazo[1,2-a]pyrazines. European journal of medicinal chemistry, 2015, Mar-26, Volume: 93 Topics: Anti-HIV Agents; Chemistry Techniques, Synthetic; Computational Biology; Drug Design; HIV Reverse Transcriptase; HIV-1; Imidazoles; Molecular Docking Simulation; Protein Conformation; Pyrazines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2015
Anti-HIV diarylpyrimidine-quinolone hybrids and their mode of action. Bioorganic & medicinal chemistry, 2015, Jul-01, Volume: 23, Issue:13 Topics: Anti-HIV Agents; Binding Sites; Cell Line; Drug Design; Granulocyte Precursor Cells; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Molecular Docking Simulation; Pyrimidines; Quinolones; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Virus Latency	2015
Discovery of piperidin-4-yl-aminopyrimidine derivatives as potent non-nucleoside HIV-1 reverse transcriptase inhibitors. European journal of medicinal chemistry, 2015, Jun-05, Volume: 97 Topics: Anti-HIV Agents; Cells, Cultured; Drug Discovery; HIV Reverse Transcriptase; Humans; Molecular Structure; Nitriles; Piperidines; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2015
Hybrid chemistry. Part 4: Discovery of etravirine-VRX-480773 hybrids as potent HIV-1 non-nucleoside reverse transcriptase inhibitors. Bioorganic & medicinal chemistry, 2015, Aug-01, Volume: 23, Issue:15 Topics: Acetanilides; Anti-HIV Agents; Cell Line; Chemistry Techniques, Synthetic; Drug Discovery; Drug Evaluation, Preclinical; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Dynamics Simulation; Nitriles; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Triazoles	2015
Pyrimidine sulfonylacetanilides with improved potency against key mutant viruses of HIV-1 by specific targeting of a highly conserved residue. European journal of medicinal chemistry, 2015, Sep-18, Volume: 102 Topics: Acetanilides; Anti-HIV Agents; Conserved Sequence; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Molecular Structure; Mutation; Pyrimidines; Reverse Transcriptase Inhibitors; Tumor Cells, Cultured	2015
A novel family of diarylpyrimidines (DAPYs) featuring a diatomic linker: Design, synthesis and anti-HIV activities. Bioorganic & medicinal chemistry, 2015, Oct-15, Volume: 23, Issue:20 Topics: Anti-HIV Agents; Dose-Response Relationship, Drug; Drug Design; HIV-1; HIV-2; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Pyrimidines; Structure-Activity Relationship	2015
Design, synthesis and anti-HIV evaluation of novel diarylpyridine derivatives targeting the entrance channel of NNRTI binding pocket. European journal of medicinal chemistry, 2016, Feb-15, Volume: 109 Topics: Anti-HIV Agents; Binding Sites; Drug Design; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Docking Simulation; Point Mutation; Pyridines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2016
Design, synthesis and evaluation of novel HIV-1 NNRTIs with dual structural conformations targeting the entrance channel of the NNRTI binding pocket. European journal of medicinal chemistry, 2016, Jun-10, Volume: 115 Topics: Anti-HIV Agents; Binding Sites; Dose-Response Relationship, Drug; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Virus Replication	2016
1,6-Bis[(benzyloxy)methyl]uracil derivatives-Novel antivirals with activity against HIV-1 and influenza H1N1 virus. Bioorganic & medicinal chemistry, 2016, 06-01, Volume: 24, Issue:11 Topics: Animals; Antiviral Agents; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; HIV-1; Influenza A Virus, H1N1 Subtype; Madin Darby Canine Kidney Cells; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Uracil	2016
Systematic evaluation of methyl ester bioisosteres in the context of developing alkenyldiarylmethanes (ADAMs) as non-nucleoside reverse transcriptase inhibitors (NNRTIs) for anti-HIV-1 chemotherapy. Bioorganic & medicinal chemistry, 2016, 07-01, Volume: 24, Issue:13 Topics: Anti-HIV Agents; Drug Stability; Esters; HIV-1; Humans; Inhibitory Concentration 50; Methane; Models, Molecular; Reverse Transcriptase Inhibitors	2016
Structural optimization of pyridine-type DAPY derivatives to exploit the tolerant regions of the NNRTI binding pocket. European journal of medicinal chemistry, 2016, Oct-04, Volume: 121 Topics: Binding Sites; Dose-Response Relationship, Drug; Drug Design; HIV Reverse Transcriptase; Molecular Docking Simulation; Protein Conformation; Pyridines; Pyrimidines; Reverse Transcriptase Inhibitors; Solubility; Structure-Activity Relationship; Water	2016
Discovery and Structure-Based Optimization of 2-Ureidothiophene-3-carboxylic Acids as Dual Bacterial RNA Polymerase and Viral Reverse Transcriptase Inhibitors. Journal of medicinal chemistry, 2016, Aug-11, Volume: 59, Issue:15 Topics: Anti-Bacterial Agents; Anti-HIV Agents; Carboxylic Acids; DNA-Directed RNA Polymerases; Dose-Response Relationship, Drug; Drug Discovery; Enzyme Inhibitors; Escherichia coli; HEK293 Cells; HeLa Cells; HIV; Humans; Microbial Sensitivity Tests; Molecular Structure; RNA-Directed DNA Polymerase; Structure-Activity Relationship; Thiophenes	2016
Discovery, characterization, and lead optimization of 7-azaindole non-nucleoside HIV-1 reverse transcriptase inhibitors. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Animals; Binding Sites; Cell Survival; Chlorocebus aethiops; Drug Evaluation, Preclinical; HIV Reverse Transcriptase; HIV-1; Humans; Indoles; Molecular Docking Simulation; Mutagenesis, Site-Directed; Protein Binding; Protein Structure, Tertiary; Reverse Transcriptase Inhibitors; Vero Cells	2016
2,4,5-Trisubstituted thiazole derivatives as HIV-1 NNRTIs effective on both wild-type and mutant HIV-1 reverse transcriptase: Optimization of the substitution of positions 4 and 5. European journal of medicinal chemistry, 2016, Nov-10, Volume: 123 Topics: Drug Design; HEK293 Cells; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Docking Simulation; Mutation; Protein Conformation; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thiazoles	2016
Computer-aided discovery of anti-HIV agents. Bioorganic & medicinal chemistry, 2016, 10-15, Volume: 24, Issue:20 Topics: Anti-HIV Agents; Computer-Aided Design; Dose-Response Relationship, Drug; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; T-Lymphocytes	2016
Arylazolyl(azinyl)thioacetanilides. Part 20: Discovery of novel purinylthioacetanilides derivatives as potent HIV-1 NNRTIs via a structure-based bioisosterism approach. Bioorganic & medicinal chemistry, 2016, 09-15, Volume: 24, Issue:18 Topics: Acetanilides; Anti-HIV Agents; Carbon-13 Magnetic Resonance Spectroscopy; HIV-1; Models, Molecular; Proton Magnetic Resonance Spectroscopy; Reverse Transcriptase Inhibitors; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship	2016
Design, Synthesis, and Evaluation of Thiophene[3,2-d]pyrimidine Derivatives as HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with Significantly Improved Drug Resistance Profiles. Journal of medicinal chemistry, 2016, 09-08, Volume: 59, Issue:17 Topics: Animals; Anti-HIV Agents; Cell Line, Tumor; Drug Resistance, Viral; Heterocyclic Compounds, 2-Ring; HIV Reverse Transcriptase; HIV-1; Humans; Male; Mice; Molecular Docking Simulation; Mutation; Pyrimidines; Rats, Sprague-Dawley; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Sulfonamides; Thiophenes	2016
Discovery of uracil-bearing DAPYs derivatives as novel HIV-1 NNRTIs via crystallographic overlay-based molecular hybridization. European journal of medicinal chemistry, 2017, Apr-21, Volume: 130 Topics: Animals; Anti-HIV Agents; Cell Line; Drug Discovery; HIV Reverse Transcriptase; HIV-1; Mice; Models, Molecular; Reverse Transcriptase Inhibitors; Solubility; Structure-Activity Relationship; Uracil	2017
Structural modifications of diarylpyrimidines (DAPYs) as HIV-1 NNRTIs: Synthesis, anti-HIV activities and SAR. Bioorganic & medicinal chemistry, 2017, 04-15, Volume: 25, Issue:8 Topics: Anti-HIV Agents; Carbon-13 Magnetic Resonance Spectroscopy; HIV-1; Molecular Docking Simulation; Proton Magnetic Resonance Spectroscopy; Pyrimidines; Reverse Transcriptase Inhibitors; Spectrometry, Mass, Electrospray Ionization	2017
Design and synthesis of hybrids of diarylpyrimidines and diketo acids as HIV-1 inhibitors. Bioorganic & medicinal chemistry letters, 2017, 04-15, Volume: 27, Issue:8 Topics: Anti-HIV Agents; Cell Line; Drug Design; HIV Infections; HIV Integrase; HIV Integrase Inhibitors; HIV-1; Humans; Keto Acids; Molecular Docking Simulation; Pyrimidines; Reverse Transcriptase Inhibitors	2017
Structure-Based Optimization of Thiophene[3,2-d]pyrimidine Derivatives as Potent HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with Improved Potency against Resistance-Associated Variants. Journal of medicinal chemistry, 2017, 05-25, Volume: 60, Issue:10 Topics: Animals; Anti-HIV Agents; Drug Resistance, Viral; HEK293 Cells; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Pyrimidines; Rats, Sprague-Dawley; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thiophenes	2017
Searching for novel N Bioorganic & medicinal chemistry, 2017, 07-15, Volume: 25, Issue:14 Topics: Benzimidazoles; Binding Sites; Drug Design; HIV Reverse Transcriptase; HIV-1; Hydrogen Bonding; Inhibitory Concentration 50; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2017
Chiral Indolylarylsulfone Non-Nucleoside Reverse Transcriptase Inhibitors as New Potent and Broad Spectrum Anti-HIV-1 Agents. Journal of medicinal chemistry, 2017, 08-10, Volume: 60, Issue:15 Topics: Animals; Anti-HIV Agents; Cells, Cultured; Glutamic Acid; HIV-1; Humans; Indoles; Lipopolysaccharides; Mice, Inbred C57BL; Microglia; Molecular Docking Simulation; Mutation; Neurons; Neuroprotective Agents; Reverse Transcriptase Inhibitors; Stereoisomerism; Structure-Activity Relationship; Sulfones	2017
Design, synthesis and anti-HIV evaluation of novel diarylpyridine derivatives as potent HIV-1 NNRTIs. European journal of medicinal chemistry, 2017, Nov-10, Volume: 140 Topics: Anti-HIV Agents; Carbon-13 Magnetic Resonance Spectroscopy; Cell Line; Drug Design; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Proton Magnetic Resonance Spectroscopy; Reverse Transcriptase Inhibitors; Spectrometry, Mass, Electrospray Ionization	2017
Structural optimization of N Bioorganic & medicinal chemistry, 2018, 02-01, Volume: 26, Issue:3 Topics: Benzimidazoles; Binding Sites; Cell Line; Cell Survival; HIV Reverse Transcriptase; HIV-1; Humans; Hydrogen Bonding; Molecular Docking Simulation; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Virus Replication	2018
Discovery of biphenyl-substituted diarylpyrimidines as non-nucleoside reverse transcriptase inhibitors with high potency against wild-type and mutant HIV-1. European journal of medicinal chemistry, 2018, Feb-10, Volume: 145 Topics: Anti-HIV Agents; Biphenyl Compounds; Cell Survival; Dose-Response Relationship, Drug; Drug Discovery; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mutation; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Tumor Cells, Cultured	2018
First discovery of a potential carbonate prodrug of NNRTI drug candidate RDEA427 with submicromolar inhibitory activity against HIV-1 K103N/Y181C double mutant strain. Bioorganic & medicinal chemistry letters, 2018, 05-01, Volume: 28, Issue:8 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cell Line, Tumor; Cyclopropanes; HIV Reverse Transcriptase; HIV-1; Humans; Hydrolysis; Mutation; Nevirapine; Nitriles; Prodrugs; Pyridazines; Pyrimidines; Pyrroles; Reverse Transcriptase Inhibitors	2018
The discovery of novel diarylpyri(mi)dine derivatives with high level activity against a wide variety of HIV-1 strains as well as against HIV-2. Bioorganic & medicinal chemistry, 2018, 05-01, Volume: 26, Issue:8 Topics: Allosteric Regulation; Binding Sites; Drug Design; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Molecular Docking Simulation; Protein Structure, Tertiary; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2018
Targeting the entrance channel of NNIBP: Discovery of diarylnicotinamide 1,4-disubstituted 1,2,3-triazoles as novel HIV-1 NNRTIs with high potency against wild-type and E138K mutant virus. European journal of medicinal chemistry, 2018, May-10, Volume: 151 Topics: Anti-HIV Agents; Drug Design; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Docking Simulation; Niacinamide; Point Mutation; Structure-Activity Relationship; Triazoles	2018
Discovery of Novel Diarylpyrimidine Derivatives as Potent HIV-1 NNRTIs Targeting the "NNRTI Adjacent" Binding Site. ACS medicinal chemistry letters, 2018, Apr-12, Volume: 9, Issue:4 Topics:	2018
Further Exploring Solvent-Exposed Tolerant Regions of Allosteric Binding Pocket for Novel HIV-1 NNRTIs Discovery. ACS medicinal chemistry letters, 2018, Apr-12, Volume: 9, Issue:4 Topics:	2018
Design and synthesis of a novel series of non-nucleoside HIV-1 inhibitors bearing pyrimidine and N-substituted aromatic piperazine. Bioorganic & medicinal chemistry letters, 2018, 12-01, Volume: 28, Issue:22 Topics: Binding Sites; Cell Line; Drug Design; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Docking Simulation; Nitrogen; Piperazine; Protein Structure, Tertiary; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2018
The Journey of HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) from Lab to Clinic. Journal of medicinal chemistry, 2019, 05-23, Volume: 62, Issue:10 Topics: Animals; Anti-HIV Agents; Clinical Trials as Topic; Drug Discovery; HIV Infections; HIV-1; Humans; Reverse Transcriptase Inhibitors	2019
Effect of α-Methoxy Substitution on the Anti-HIV Activity of Dihydropyrimidin-4(3 H)-ones. Journal of medicinal chemistry, 2019, 01-24, Volume: 62, Issue:2 Topics: Anti-HIV Agents; Binding Sites; Cell Line; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Docking Simulation; Mutation; Protein Structure, Tertiary; Pyrimidinones; Stereoisomerism; Structure-Activity Relationship	2019
Synthesis and biological evaluation of dihydroquinazoline-2-amines as potent non-nucleoside reverse transcriptase inhibitors of wild-type and mutant HIV-1 strains. European journal of medicinal chemistry, 2019, Aug-15, Volume: 176 Topics: Amines; Anti-HIV Agents; Binding Sites; Cell Line, Tumor; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Docking Simulation; Molecular Structure; Protein Binding; Quinazolines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2019
Conformational restriction design of thiophene-biphenyl-DAPY HIV-1 non-nucleoside reverse transcriptase inhibitors. European journal of medicinal chemistry, 2019, Nov-15, Volume: 182 Topics: Anti-HIV Agents; Biphenyl Compounds; Cell Line; Dose-Response Relationship, Drug; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Conformation; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thiophenes	2019
Ligand-Based Design of Nondimethylphenyl-Diarylpyrimidines with Improved Metabolic Stability, Safety, and Oral Pharmacokinetic Profiles. Journal of medicinal chemistry, 2019, 12-26, Volume: 62, Issue:24 Topics: Administration, Oral; Animals; Anti-HIV Agents; Apoptosis; Drug Design; Female; HIV Infections; HIV-1; Humans; Ligands; Male; Mice; Microsomes, Liver; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Rats; Reverse Transcriptase Inhibitors; Tissue Distribution; Tumor Cells, Cultured; Virus Replication	2019
Fragment hopping-based discovery of novel sulfinylacetamide-diarylpyrimidines (DAPYs) as HIV-1 nonnucleoside reverse transcriptase inhibitors. European journal of medicinal chemistry, 2020, Jan-01, Volume: 185 Topics: Acetamides; Anti-HIV Agents; Dose-Response Relationship, Drug; Drug Discovery; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2020
Indazolyl-substituted piperidin-4-yl-aminopyrimidines as HIV-1 NNRTIs: Design, synthesis and biological activities. European journal of medicinal chemistry, 2020, Jan-15, Volume: 186 Topics: Anti-HIV Agents; Dose-Response Relationship, Drug; Drug Design; HIV; HIV Reverse Transcriptase; Humans; Indazoles; Microbial Sensitivity Tests; Molecular Structure; Piperidines; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2020
Rational design and Structure-Activity relationship of coumarin derivatives effective on HIV-1 protease and partially on HIV-1 reverse transcriptase. European journal of medicinal chemistry, 2020, Jan-15, Volume: 186 Topics: Anti-HIV Agents; Cell Line; Coumarins; Dose-Response Relationship, Drug; Drug Design; HIV Infections; HIV Protease; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Docking Simulation; Molecular Structure; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2020
Discovery and Characterization of Fluorine-Substituted Diarylpyrimidine Derivatives as Novel HIV-1 NNRTIs with Highly Improved Resistance Profiles and Low Activity for the hERG Ion Channel. Journal of medicinal chemistry, 2020, 02-13, Volume: 63, Issue:3 Topics: Animals; Anti-HIV Agents; Cell Line; Crystallography, X-Ray; Drug Discovery; ERG1 Potassium Channel; Female; Fluorine; HIV Reverse Transcriptase; HIV-1; Humans; Male; Mice; Microsomes, Liver; Molecular Structure; Protein Binding; Pyrimidines; Rats, Wistar; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thiophenes	2020
In situ click chemistry-based rapid discovery of novel HIV-1 NNRTIs by exploiting the hydrophobic channel and tolerant regions of NNIBP. European journal of medicinal chemistry, 2020, May-01, Volume: 193 Topics: Anti-HIV Agents; Binding Sites; Click Chemistry; Dose-Response Relationship, Drug; Drug Discovery; HIV Reverse Transcriptase; HIV-1; Humans; Hydrophobic and Hydrophilic Interactions; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Triazoles	2020
Bioisosterism-based design and enantiomeric profiling of chiral hydroxyl-substituted biphenyl-diarylpyrimidine nonnucleoside HIV-1 reverse transcriptase inhibitors. European journal of medicinal chemistry, 2020, Sep-15, Volume: 202 Topics: Animals; Anti-HIV Agents; Body Weight; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Female; HIV Reverse Transcriptase; HIV-1; Humans; Hydroxides; Male; Mice; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Pyrimidines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2020
New indolylarylsulfone non-nucleoside reverse transcriptase inhibitors show low nanomolar inhibition of single and double HIV-1 mutant strains. European journal of medicinal chemistry, 2020, Dec-15, Volume: 208 Topics: Anti-HIV Agents; Cell Line, Tumor; Drug Design; Drug Synergism; HIV Reverse Transcriptase; HIV-1; Humans; Indoles; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Mutation; Protein Binding; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Sulfones; Zidovudine	2020
Targeting dual tolerant regions of binding pocket: Discovery of novel morpholine-substituted diarylpyrimidines as potent HIV-1 NNRTIs with significantly improved water solubility. European journal of medicinal chemistry, 2020, Nov-15, Volume: 206 Topics: Binding Sites; HIV Reverse Transcriptase; HIV-1; Morpholines; Mutation; Pyrimidines; Reverse Transcriptase Inhibitors; Solubility; Structure-Activity Relationship; Water	2020
Exploiting the tolerant region I of the non-nucleoside reverse transcriptase inhibitor (NNRTI) binding pocket. Part 2: Discovery of diarylpyrimidine derivatives as potent HIV-1 NNRTIs with high Fsp European journal of medicinal chemistry, 2021, Mar-05, Volume: 213 Topics: Anti-HIV Agents; Binding Sites; Drug Design; HIV-1; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Binding; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2021
Design, synthesis, and evaluation of "dual-site"-binding diarylpyrimidines targeting both NNIBP and the NNRTI adjacent site of the HIV-1 reverse transcriptase. European journal of medicinal chemistry, 2021, Feb-05, Volume: 211 Topics: Anti-HIV Agents; Drug Design; HIV Reverse Transcriptase; Humans; Molecular Dynamics Simulation; Molecular Structure; Pyrimidines; Structure-Activity Relationship	2021
Hydrophobic Pocket Occupation Design of Difluoro-Biphenyl-Diarylpyrimidines as Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors: from Journal of medicinal chemistry, 2021, 04-22, Volume: 64, Issue:8 Topics: Alkylation; Animals; Binding Sites; Biphenyl Compounds; Cell Line; Cell Survival; Drug Design; Drug Stability; Female; Half-Life; HIV Reverse Transcriptase; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Microsomes, Liver; Molecular Docking Simulation; Mutation; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2021
Design, synthesis and anti-HIV evaluation of novel 5-substituted diarylpyrimidine derivatives as potent HIV-1 NNRTIs. Bioorganic & medicinal chemistry, 2021, 06-15, Volume: 40 Topics: Anti-HIV Agents; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Design; HIV; HIV Reverse Transcriptase; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2021
Exploiting the hydrophobic channel of the NNIBP: Discovery of novel diarylpyrimidines as HIV-1 NNRTIs against wild-type and K103N mutant viruses. Bioorganic & medicinal chemistry, 2021, 07-15, Volume: 42 Topics: Anti-HIV Agents; Dose-Response Relationship, Drug; Drug Discovery; HIV Reverse Transcriptase; HIV-1; Humans; Hydrophobic and Hydrophilic Interactions; Microbial Sensitivity Tests; Molecular Structure; Mutation; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2021
Improving Druggability of Novel Diarylpyrimidine NNRTIs by a Fragment-Based Replacement Strategy: From Biphenyl-DAPYs to Heteroaromatic-Biphenyl-DAPYs. Journal of medicinal chemistry, 2021, 07-22, Volume: 64, Issue:14 Topics: Animals; Anti-HIV Agents; Dose-Response Relationship, Drug; Female; HIV Reverse Transcriptase; HIV-1; Humans; Male; Mice; Microbial Sensitivity Tests; Microsomes, Liver; Models, Molecular; Molecular Structure; Pyrimidines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2021
Design of the naphthyl-diarylpyrimidines as potent non-nucleoside reverse transcriptase inhibitors (NNRTIs) via structure-based extension into the entrance channel. European journal of medicinal chemistry, 2021, Dec-15, Volume: 226 Topics: Anti-HIV Agents; Dose-Response Relationship, Drug; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Naphthalenes; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2021
Discovery of Novel Pyridine-Dimethyl-Phenyl-DAPY Hybrids by Molecular Fusing of Methyl-Pyrimidine-DAPYs and Difluoro-Pyridinyl-DAPYs: Improving the Druggability toward High Inhibitory Activity, Solubility, Safety, and PK. Journal of medicinal chemistry, 2022, 02-10, Volume: 65, Issue:3 Topics: Animals; Anti-HIV Agents; Binding Sites; Cell Survival; Cytochrome P-450 Enzyme System; Drug Design; Drug Resistance, Viral; Drug Stability; Female; Half-Life; HIV Reverse Transcriptase; HIV-1; Humans; Mice; Molecular Docking Simulation; Mutation; Pyridines; Pyrimidines; Solubility; Structure-Activity Relationship	2022
Contemporary Medicinal Chemistry Strategies for the Discovery and Development of Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors. Journal of medicinal chemistry, 2022, 03-10, Volume: 65, Issue:5 Topics: Anti-HIV Agents; Chemistry, Pharmaceutical; Heterocyclic Compounds, 1-Ring; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Reverse Transcriptase Inhibitors	2022
Chemical space exploration around indolylarylsulfone scaffold led to a novel class of highly active HIV-1 NNRTIs with spiro structural features. European journal of medicinal chemistry, 2022, Aug-05, Volume: 238 Topics: Anti-HIV Agents; Drug Design; HIV Reverse Transcriptase; HIV-1; Molecular Structure; Reverse Transcriptase Inhibitors; Space Flight; Structure-Activity Relationship	2022
Structure-Based Discovery of Novel NH Journal of medicinal chemistry, 2022, 06-23, Volume: 65, Issue:12 Topics: Anti-HIV Agents; Biphenyl Compounds; Drug Design; Heterocyclic Compounds, 1-Ring; HIV Reverse Transcriptase; HIV-1; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2022
Expansion of the S-CN-DABO scaffold to exploit the impact on inhibitory activities against the non-nucleoside HIV-1 reverse transcriptase. European journal of medicinal chemistry, 2022, Aug-05, Volume: 238 Topics: Animals; Anti-HIV Agents; HIV Reverse Transcriptase; HIV-1; Mice; Molecular Docking Simulation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2022
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
[Lipodystrophy and antiretroviral agents]. Revista clinica espanola, 1999, Volume: 199, Issue:8 Topics: Acquired Immunodeficiency Syndrome; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; HIV Protease Inhibitors; HIV-1; Humans; Hyperlipidemias; Lipodystrophy; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Syndrome	1999
Non-nucleoside reverse transcriptase inhibitor resistance among patients failing a nevirapine plus protease inhibitor-containing regimen. AIDS (London, England), 2000, Jan-28, Volume: 14, Issue:2 Topics: Adult; Alkynes; Benzoxazines; Cohort Studies; Cyclopropanes; Delavirdine; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Hospitals, University; Humans; Male; Middle Aged; Mutation; Nevirapine; Oxazines; Protease Inhibitors; Retrospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Viral Load	2000
Efavirenz associated with corticosteroids in patients with previous severe hypersensitivity reaction due to nevirapine. AIDS (London, England), 2000, Feb-18, Volume: 14, Issue:3 Topics: Adrenal Cortex Hormones; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors	2000
Long-term exposure of HIV type 1-infected cell cultures to combinations of the novel quinoxaline GW420867X with lamivudine, abacavir, and a variety of nonnucleoside reverse transcriptase inhibitors. AIDS research and human retroviruses, 2000, Apr-10, Volume: 16, Issue:6 Topics: Alkynes; Anilides; Anti-HIV Agents; Benzoxazines; Cell Line; Cyclopropanes; Delavirdine; Dideoxynucleosides; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance, Microbial; Furans; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Microbial Sensitivity Tests; Mutation; Nevirapine; Oxazines; Quinoxalines; Reverse Transcriptase Inhibitors; Thioamides; Uracil	2000
Can early failure with nevirapine be rescued with efavirenz? Journal of acquired immune deficiency syndromes (1999), 2000, May-01, Volume: 24, Issue:1 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Treatment Failure	2000
Methadone withdrawal symptoms with nevirapine and efavirenz. The Annals of pharmacotherapy, 2000, Volume: 34, Issue:3 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Interactions; HIV Infections; Humans; Male; Methadone; Narcotics; Nevirapine; Oxazines; Substance Withdrawal Syndrome	2000
Salvage therapy with abacavir plus efavirenz or nevirapine in HIV-1-infected persons with previous nucleoside analogue and protease inhibitor use. AIDS (London, England), 2000, Jul-07, Volume: 14, Issue:10 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dideoxynucleosides; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Nevirapine; Oxazines; Retrospective Studies; Reverse Transcriptase Inhibitors; Salvage Therapy	2000
Switching from a PI-based to a PI-sparing regimen for management of metabolic or clinical fat redistribution. The AIDS reader, 2000, Volume: 10, Issue:8 Topics: Acquired Immunodeficiency Syndrome; Adipose Tissue; Alkynes; Benzoxazines; Cyclopropanes; Dideoxynucleosides; HIV Protease Inhibitors; Humans; Lipodystrophy; Nevirapine; Oxazines	2000
Comment: opiate withdrawal symptoms induced by antiretroviral drugs. The Annals of pharmacotherapy, 2000, Volume: 34, Issue:9 Topics: Alkynes; Analgesics, Opioid; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Humans; Methadone; Nevirapine; Opioid-Related Disorders; Oxazines; Substance Withdrawal Syndrome	2000
Is there cross-toxicity between nevirapine and efavirenz in subjects developing rash? AIDS (London, England), 2000, Jul-28, Volume: 14, Issue:11 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Eruptions; Exanthema; HIV Infections; Humans; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors	2000
Absence of association between individual thymidine analogues or nonnucleoside analogues and lipid abnormalities in HIV-1-infected persons on initial therapy. Journal of acquired immune deficiency syndromes (1999), 2000, Aug-01, Volume: 24, Issue:4 Topics: Adult; Alkynes; Anti-HIV Agents; Arteriosclerosis; Benzoxazines; Cholesterol; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lipids; Male; Nevirapine; Oxazines; Risk Factors; Stavudine; Thymidine; Triglycerides; Zidovudine	2000
The tolerability of efavirenz after nevirapine-related adverse events. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2000, Volume: 31, Issue:3 Topics: Adult; Aged; Alkynes; Anti-HIV Agents; Anxiety Disorders; Benzoxazines; Cyclopropanes; Female; HIV; HIV Infections; Homosexuality; Humans; Male; Middle Aged; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors	2000
Structural basis for the resilience of efavirenz (DMP-266) to drug resistance mutations in HIV-1 reverse transcriptase. Structure (London, England : 1993), 2000, Oct-15, Volume: 8, Issue:10 Topics: Alkynes; Amino Acid Substitution; Anti-HIV Agents; Benzoxazines; Binding Sites; Crystallography, X-Ray; Cyclopropanes; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Mutation; Nevirapine; Oxazines; Protein Binding; Protein Conformation; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2000
Inhibition of human cytochrome P450 isoforms by nonnucleoside reverse transcriptase inhibitors. Journal of clinical pharmacology, 2001, Volume: 41, Issue:1 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Delavirdine; Humans; Hydrolysis; Inhibitory Concentration 50; Isoenzymes; Microsomes, Liver; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Triazolam	2001
Potentiation of inhibition of wild-type and mutant human immunodeficiency virus type 1 reverse transcriptases by combinations of nonnucleoside inhibitors and d- and L-(beta)-dideoxynucleoside triphosphate analogs. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:4 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Dideoxynucleotides; DNA Replication; DNA, Viral; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Drug Synergism; HIV Reverse Transcriptase; Humans; Inhibitory Concentration 50; Mutation; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Stereoisomerism; Thymine Nucleotides; Zidovudine	2001
Genotypic correlates of phenotypic resistance to efavirenz in virus isolates from patients failing nonnucleoside reverse transcriptase inhibitor therapy. Journal of virology, 2001, Volume: 75, Issue:11 Topics: Alkynes; Amino Acid Substitution; Anti-HIV Agents; Benzoxazines; Cells, Cultured; Clinical Trials, Phase II as Topic; Cohort Studies; Cyclopropanes; Delavirdine; Drug Resistance, Microbial; Drug Resistance, Multiple; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Leukocytes, Mononuclear; Microbial Sensitivity Tests; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Treatment Failure	2001
Viracept combination studies. AIDS patient care and STDs, 1998, Volume: 12, Issue:6 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Therapy, Combination; Humans; Indinavir; Nelfinavir; Nevirapine; Oxazines; Ritonavir; Saquinavir; Stavudine	1998
NNRTIs: a neglected class. GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1998, Volume: 12, Issue:9 Topics: Alkynes; Benzoxazines; Clinical Trials as Topic; Cyclopropanes; Delavirdine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; Humans; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors	1998
Methadone and anti-HIV drugs. The Body positive, 1999, Volume: 12, Issue:5 Topics: Alkynes; Analgesics, Opioid; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Interactions; HIV Infections; Humans; Methadone; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Substance-Related Disorders	1999
Switching drugs for lipodystophy. The Body positive, 1999, Volume: 12, Issue:5 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cholesterol; Cyclopropanes; Drug Administration Schedule; HIV Infections; Humans; Lipodystrophy; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Triglycerides	1999
Strategy update: protease-sparing regimens. Project Inform perspective, 1998, Issue:26 Topics: Alkynes; Benzoxazines; Cyclopropanes; Delavirdine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors	1998
[Results of the AIDS-In-Europe Study. Non-nucleoside reverse transcriptase inhibitor does not equal non-nucleoside reverse transcriptase inhibitor]. MMW Fortschritte der Medizin, 2001, Apr-02, Volume: 143 Suppl 1 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Clinical Trials as Topic; Cyclopropanes; HIV; HIV Infections; Humans; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Treatment Outcome	2001
A single amino acid change at Leu-188 in the reverse transcriptase of HIV-2 and SIV renders them sensitive to non-nucleoside reverse transcriptase inhibitors. Archives of virology, 2001, Volume: 146, Issue:4 Topics: Alkynes; Amino Acid Sequence; Amino Acid Substitution; Anti-HIV Agents; Benzoxazines; Cell Line; Cyclopropanes; Delavirdine; Drug Resistance, Microbial; HeLa Cells; HIV Reverse Transcriptase; HIV-2; Humans; Leucine; Molecular Sequence Data; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Sequence Homology, Amino Acid; Simian Immunodeficiency Virus; Species Specificity	2001
Antiretrovirals: simultaneous determination of five protease inhibitors and three nonnucleoside transcriptase inhibitors in human plasma by a rapid high-performance liquid chromatography--mass spectrometry assay. Therapeutic drug monitoring, 2001, Volume: 23, Issue:4 Topics: Alkynes; Benzoxazines; Carbamates; Chromatography, Liquid; Cyclopropanes; Delavirdine; Drug Monitoring; Furans; HIV Protease Inhibitors; Humans; Indinavir; Mass Spectrometry; Nelfinavir; Nevirapine; Oxazines; Reproducibility of Results; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Sensitivity and Specificity; Sulfonamides	2001
In vitro anti-HIV-1 synergy between non-nucleoside reverse transcriptase inhibitors nevirapine and efavirenz. Antiviral therapy, 2001, Volume: 6, Issue:2 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; In Vitro Techniques; Inhibitory Concentration 50; Leukocytes, Mononuclear; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Virus Replication	2001
Resistance profile and cross-resistance of HIV-1 among patients failing a non-nucleoside reverse transcriptase inhibitor-containing regimen. Journal of medical virology, 2001, Volume: 65, Issue:3 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Multiple, Viral; Drug Resistance, Viral; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Failure	2001
Drugs for HIV infection. The Medical letter on drugs and therapeutics, 2001, Nov-26, Volume: 43, Issue:1119 Topics: Alkynes; Benzoxazines; Cyclopropanes; Delavirdine; Didanosine; Dose-Response Relationship, Drug; HIV Infections; HIV Protease Inhibitors; Humans; Nelfinavir; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Saquinavir; Stavudine; Zidovudine	2001
Hepatotoxicity associated with nevirapine or efavirenz-containing antiretroviral therapy: role of hepatitis C and B infections. Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1 Topics: Adult; Alanine Transaminase; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Aspartate Aminotransferases; Benzoxazines; Bilirubin; Chemical and Drug Induced Liver Injury; Cyclopropanes; Female; Hepatitis B; Hepatitis C; HIV Infections; Humans; Liver Diseases; Male; Nevirapine; Oxazines; Prospective Studies; Reverse Transcriptase Inhibitors; Risk Factors; Treatment Outcome	2002
Nevirapine + efavirenz based salvage therapy in heavily pretreated HIV infected patients. Sexually transmitted infections, 2002, Volume: 78, Issue:1 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Combinations; HIV Infections; Humans; Nevirapine; Oxazines; Retrospective Studies; Salvage Therapy	2002
Virologic and immunologic response to regimens containing nevirapine or efavirenz in combination with 2 nucleoside analogues in the Italian Cohort Naive Antiretrovirals (I.Co.N.A.) study. The Journal of infectious diseases, 2002, Apr-15, Volume: 185, Issue:8 Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cohort Studies; Cyclopropanes; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Nevirapine; Oxazines; RNA, Viral	2002
Genotype resistance profiles in patients failing an NNRTI-containing regimen, and modifications after stopping NNRTI therapy. Journal of clinical laboratory analysis, 2002, Volume: 16, Issue:2 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Genotype; HIV Infections; HIV-1; Humans; Mutation; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Treatment Failure; Viral Load	2002
Potency of nonnucleoside reverse transcriptase inhibitors (NNRTIs) used in combination with other human immunodeficiency virus NNRTIs, NRTIs, or protease inhibitors. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:6 Topics: Alkynes; Benzoxazines; Cells, Cultured; Cyclopropanes; Drug Combinations; Drug Interactions; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Nevirapine; Nucleosides; Oxazines; Reverse Transcriptase Inhibitors; Virus Replication	2002
High-performance liquid chromatographic method for the simultaneous determination of the six HIV-protease inhibitors and two non-nucleoside reverse transcriptase inhibitors in human plasma. Therapeutic drug monitoring, 2002, Volume: 24, Issue:3 Topics: Alkynes; Benzoxazines; Carbamates; Chromatography, High Pressure Liquid; Cyclopropanes; Drug Monitoring; Furans; HIV Infections; Humans; Indinavir; Lopinavir; Nelfinavir; Nevirapine; Oxazines; Protease Inhibitors; Pyrimidinones; Reproducibility of Results; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Sulfonamides	2002
Simple and rapid quantification of the non-nucleoside reverse transcriptase inhibitors nevirapine, delavirdine, and efavirenz in human blood plasma using high-performance liquid chromatography with ultraviolet absorbance detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2002, Jul-05, Volume: 774, Issue:1 Topics: Alkynes; Benzoxazines; Chromatography, High Pressure Liquid; Cyclopropanes; Delavirdine; HIV Infections; HIV-1; Humans; Nevirapine; Oxazines; Reference Standards; Reproducibility of Results; Reverse Transcriptase Inhibitors; Sensitivity and Specificity; Spectrophotometry, Ultraviolet	2002
Genetic divergence of human immunodeficiency virus type 1 Ethiopian clade C reverse transcriptase (RT) and rapid development of resistance against nonnucleoside inhibitors of RT. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:7 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; Genetic Variation; Genotype; HIV Reverse Transcriptase; HIV-1; Nevirapine; Oxazines; Phylogeny; Reverse Transcriptase Inhibitors; Zidovudine	2002
NNRTIs compared in switch group. AIDS patient care and STDs, 2002, Volume: 16, Issue:6 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; HIV Infections; Humans; Nevirapine; Oxazines; Randomized Controlled Trials as Topic; Treatment Outcome; Viral Load	2002
Extent and importance of cross-resistance to efavirenz after nevirapine failure. AIDS research and human retroviruses, 2002, Jul-20, Volume: 18, Issue:11 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; Female; HIV Infections; Humans; Male; Nevirapine; Oxazines; Prospective Studies; Treatment Failure	2002
Differential modulation of P-glycoprotein expression and activity by non-nucleoside HIV-1 reverse transcriptase inhibitors in cell culture. Pharmaceutical research, 2002, Volume: 19, Issue:7 Topics: Alkynes; Anti-HIV Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzoxazines; Caco-2 Cells; Cyclopropanes; Delavirdine; Dose-Response Relationship, Drug; HIV Reverse Transcriptase; Humans; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Tumor Cells, Cultured	2002
When will once (-a day) be enough? The Hopkins HIV report : a bimonthly newsletter for healthcare providers, 2000, Volume: 12, Issue:3 Topics: Acquired Immunodeficiency Syndrome; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Deoxycytidine; Didanosine; Emtricitabine; Humans; Hydroxyurea; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Zidovudine	2000
Cross-resistance among nonnucleoside reverse transcriptase inhibitors limits recycling efavirenz after nevirapine failure. AIDS research and human retroviruses, 2002, Aug-10, Volume: 18, Issue:12 Topics: Alkynes; Benzoxazines; Cyclopropanes; Drug Resistance, Microbial; HIV Infections; HIV-1; Humans; Mutation; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; RNA, Viral	2002
Inhibitor binding alters the directions of domain motions in HIV-1 reverse transcriptase. Proteins, 2002, Oct-01, Volume: 49, Issue:1 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Binding Sites; Cyclopropanes; Drug Delivery Systems; HIV Reverse Transcriptase; Ligands; Models, Molecular; Motion; Nevirapine; Oxazines; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Reverse Transcriptase Inhibitors; Ribonuclease H; Structure-Activity Relationship	2002
Evaluation of antiretroviral drug measurements by an interlaboratory quality control program. Journal of acquired immune deficiency syndromes (1999), 2003, Mar-01, Volume: 32, Issue:3 Topics: Alkynes; Australia; Benzoxazines; Canada; Carbamates; Cyclopropanes; Europe; Furans; HIV Protease Inhibitors; Humans; International Cooperation; Laboratories; Lopinavir; Nevirapine; Oxazines; Pyrimidinones; Quality Control; Reference Standards; Reproducibility of Results; Reverse Transcriptase Inhibitors; Sulfonamides; United States	2003
Comparing liver toxicity between efavirenz and nevirapine. TreatmentUpdate, 2002, Volume: 14, Issue:2 Topics: Alkynes; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Female; HIV Infections; Humans; Male; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Viral Load	2002
Report from the Tenth Retrovirus Conference. Comparing efavirenz and nevirapine: the 2NN study. AIDS clinical care, 2003, Volume: 15, Issue:4 Topics: Alkynes; Benzoxazines; Clinical Trials as Topic; Cyclopropanes; HIV Infections; Humans; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors	2003
Simplification of protease inhibitor-containing regimens with efavirenz, nevirapine or abacavir: safety and efficacy outcomes. Antiviral therapy, 2003, Volume: 8, Issue:1 Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Dideoxynucleosides; Drug Administration Schedule; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Nevirapine; Oxazines; Retrospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome	2003
[Decrease of HIV-1 virus load by nevirapin/efavirenz]. Deutsche medizinische Wochenschrift (1946), 2003, May-09, Volume: 128, Issue:19 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; HIV Infections; HIV-1; Humans; Nevirapine; Oxazines; Treatment Outcome; Viral Load	2003
[Assessment of adherence to antiretroviral: role of determination of plasma levels of non nucleosides anologues]. Medicina clinica, 2003, May-17, Volume: 120, Issue:18 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cross-Sectional Studies; Cyclopropanes; Female; HIV Seropositivity; Humans; Male; Nevirapine; Oxazines; Patient Compliance; Reproducibility of Results; Self-Assessment; Surveys and Questionnaires	2003
Interruption of nonnucleoside reverse transcriptase inhibitor (NNRTI) therapy for 2 months has no effect on levels of human immunodeficiency virus type 1 in plasma of patients harboring viruses with mutations associated with resistance to NNRTIs. Journal of clinical microbiology, 2003, Volume: 41, Issue:6 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load	2003
Hypersusceptibility to non-nucleoside reverse transcriptase inhibitors in HIV-1. AIDS (London, England), 2003, Jun-13, Volume: 17, Issue:9 Topics: Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Delavirdine; Drug Resistance, Multiple, Viral; HIV Infections; HIV-1; Humans; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors	2003
Use of SAM2 biotin capture membrane in microarrayed compound screening (muARCS) format for nucleic acid polymerization assays. Journal of biomolecular screening, 2003, Volume: 8, Issue:3 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Biotin; Biotinylation; Cyclopropanes; DNA; Dose-Response Relationship, Drug; HIV Reverse Transcriptase; Inhibitory Concentration 50; Nevirapine; Nucleic Acids; Oligonucleotide Array Sequence Analysis; Oxazines; Plasmids; RNA; RNA-Directed DNA Polymerase; Sensitivity and Specificity; Templates, Genetic	2003
Simple and rapid method for the simultaneous determination of the non-nucleoside reverse transcriptase inhibitors efavirenz and nevirapine in human plasma using liquid chromatography. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2003, Jul-25, Volume: 792, Issue:2 Topics: Alkynes; Benzoxazines; Chromatography, High Pressure Liquid; Cyclopropanes; HIV Infections; HIV-1; Humans; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors	2003
Risk of severe hepatotoxicity associated with antiretroviral therapy in the HIV-NAT Cohort, Thailand, 1996-2001. AIDS (London, England), 2003, Oct-17, Volume: 17, Issue:15 Topics: Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Chemical and Drug Induced Liver Injury; Cyclopropanes; Female; Hepatitis B; Hepatitis C; HIV Infections; HIV Protease Inhibitors; Humans; Incidence; Liver; Liver Diseases; Male; Nevirapine; Oxazines; Prevalence; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Risk Factors; Thailand	2003
Does prior short-course nevirapine reduce the effectiveness of subsequent combination treatment with efavirenz? Journal of acquired immune deficiency syndromes (1999), 2003, Nov-01, Volume: 34, Issue:3 Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Longitudinal Studies; Male; Middle Aged; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors	2003
Risk and determinants of developing severe liver toxicity during therapy with nevirapine-and efavirenz-containing regimens in HIV-infected patients. International journal of STD & AIDS, 2003, Volume: 14, Issue:11 Topics: Adult; Alanine Transaminase; Alcoholism; Alkynes; Anti-HIV Agents; Benzoxazines; Chemical and Drug Induced Liver Injury; Cohort Studies; Cyclopropanes; Drug Therapy, Combination; Female; Hepatitis C Antibodies; Hepatitis C, Chronic; HIV Infections; HIV Protease Inhibitors; Humans; Liver Diseases; Male; Multivariate Analysis; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Risk; Risk Factors; Transaminases	2003
Substitution for protease inhibitors in HIV therapy. The New England journal of medicine, 2003, Dec-18, Volume: 349, Issue:25 Topics: Alkynes; Benzoxazines; Cyclopropanes; HIV Infections; HIV Protease Inhibitors; Humans; Nevirapine; Oxazines; Patient Dropouts; Reverse Transcriptase Inhibitors; Substance Abuse, Intravenous	2003
Provider bias in the selection of non-nucleoside reverse transcriptase inhibitor and protease inhibitor-based highly active antiretroviral therapy and HIV treatment outcomes in observational studies. AIDS (London, England), 2003, Dec-05, Volume: 17, Issue:18 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cohort Studies; Cyclopropanes; Delavirdine; Female; HIV Infections; HIV Protease Inhibitors; Humans; Male; Middle Aged; Nevirapine; Oxazines; Prejudice; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome	2003
Nevirapine plus efavirenz plus didanosine: a simple, safe, and effective once-daily regimen for patients with HIV infection. Journal of the National Medical Association, 2003, Volume: 95, Issue:12 Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cohort Studies; Cyclopropanes; Didanosine; Drug Administration Schedule; Female; HIV Infections; HIV-1; Humans; Male; Nevirapine; Oxazines; Retrospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome	2003
[A "once daily" drug that with proven effectiveness. Efavirenz has successful outcome also in direct comparisons]. MMW Fortschritte der Medizin, 2003, Apr-28, Volume: 145 Spec No 1 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dose-Response Relationship, Drug; Drug Administration Schedule; HIV Infections; Humans; Nevirapine; Oxazines; Randomized Controlled Trials as Topic; Treatment Outcome	2003
[Nevirapine has gained acceptance. Good antiretroviral effect--favorable lipid profile]. MMW Fortschritte der Medizin, 2003, Apr-28, Volume: 145 Spec No 1 Topics: Acquired Immunodeficiency Syndrome; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Nevirapine; Oxazines; Randomized Controlled Trials as Topic	2003
[CROI highlights of D:A:D Study (Data Collection on Adverse Events of Anti-HIV Drugs Study) and 2NN Study. Stepping into the grease pot]. MMW Fortschritte der Medizin, 2003, Apr-28, Volume: 145 Spec No 1 Topics: Acquired Immunodeficiency Syndrome; Adverse Drug Reaction Reporting Systems; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Data Collection; Humans; Lipids; Myocardial Infarction; Nevirapine; Oxazines; Treatment Outcome	2003
Nevirapine- versus efavirenz-based highly active antiretroviral therapy regimens in antiretroviral-naïve patients with advanced HIV infection. HIV medicine, 2004, Volume: 5, Issue:2 Topics: Adolescent; Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cohort Studies; Cyclopropanes; Female; HIV Infections; Humans; Male; Nevirapine; Oxazines; Retrospective Studies; Treatment Failure; Treatment Outcome	2004
Genetic variation at NNRTI resistance-associated positions in patients infected with HIV-1 subtype C. AIDS (London, England), 2004, Apr-09, Volume: 18, Issue:6 Topics: Adult; Alkynes; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; Female; Genetic Variation; HIV Infections; HIV-1; Humans; Male; Mutation; Nevirapine; Nucleosides; Oxazines; Polymorphism, Genetic; Reverse Transcriptase Inhibitors; RNA, Viral	2004
Safe substitution for efavirenz. AIDS patient care and STDs, 2004, Volume: 18, Issue:1 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Central Nervous System Diseases; Cyclopropanes; HIV Infections; Humans; Hyperlipidemias; Nevirapine; Oxazines; Patient Selection; Retrospective Studies; Treatment Outcome; Viral Load	2004
Antiretroviral therapy for previously untreated HIV-1-infected adults: 2NN, or just one? Lancet (London, England), 2004, Apr-17, Volume: 363, Issue:9417 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors	2004
Predictors of virologic failure and resistance in HIV-infected patients treated with nevirapine- or efavirenz-based antiretroviral therapy. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2004, May-01, Volume: 38, Issue:9 Topics: Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; Female; Forecasting; Guideline Adherence; HIV; HIV Infections; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Nevirapine; Oxazines; Treatment Failure; Viral Load	2004
HIV/AIDS news: comparable anti-HIV antiviral efficacy of Viramune and Efavirenz--the Lancet publishes first large-scale comparison study. Infection, 2004, Volume: 32, Issue:3 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Multicenter Studies as Topic; Nevirapine; Oxazines; Randomized Controlled Trials as Topic; Research Design; Reverse Transcriptase Inhibitors; Treatment Outcome	2004
Rate of viral rebound according to specific drugs in the regimen in 2120 patients with HIV suppression. AIDS (London, England), 2004, Sep-03, Volume: 18, Issue:13 Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Cohort Studies; Cyclopropanes; Dideoxynucleosides; Female; HIV Infections; Humans; Male; Nelfinavir; Nevirapine; Oxazines; Prospective Studies; Viral Load	2004
[CROI--presentation of new study results. In a comparison of NNRTI nevirapine is equally effective]. MMW Fortschritte der Medizin, 2004, Apr-26, Volume: 146 Spec No 1 Topics: Alkynes; Benzoxazines; CD4 Lymphocyte Count; Clinical Trials as Topic; Cyclopropanes; HIV Infections; HIV-1; Humans; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Treatment Outcome; Viral Load	2004
Higher efavirenz concentrations determine the response to viruses carrying non-nucleoside reverse transcriptase resistance mutations. AIDS (London, England), 2004, Oct-21, Volume: 18, Issue:15 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Mutation; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Treatment Failure; Viral Load	2004
Antiretroviral drug pharmacokinetics in hepatitis with hepatic dysfunction. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Jan-01, Volume: 40, Issue:1 Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Therapy, Combination; Hepatitis; HIV Infections; Humans; Indinavir; Liver Function Tests; Lopinavir; Nelfinavir; Nevirapine; Oxazines; Protease Inhibitors; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Zidovudine	2005
Warning on two specific 3-drug regimens: Viread + Didanosine + either Sustiva or Viramune. AIDS treatment news, 2004, Oct-29, Issue:406 Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Nevirapine; Organophosphonates; Oxazines; Tenofovir; United States; United States Food and Drug Administration	2004
Efavirenz enhances the proteolytic processing of an HIV-1 pol polyprotein precursor and reverse transcriptase homodimer formation. FEBS letters, 2005, Jan-17, Volume: 579, Issue:2 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dimerization; Fusion Proteins, gag-pol; HIV Reverse Transcriptase; Humans; Nevirapine; Oxazines; Protein Precursors; Reverse Transcriptase Inhibitors; Two-Hybrid System Techniques	2005
In vivo dynamics of the 103N mutation following the withdrawal of non-nucleoside reverse transcriptase inhibitors in HIV-infected patients: preliminary results. The new microbiologica, 2004, Volume: 27, Issue:2 Suppl 1 Topics: Alkynes; Amino Acid Substitution; Base Sequence; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Delavirdine; DNA, Complementary; Drug Resistance, Viral; HIV; HIV Infections; HIV Reverse Transcriptase; Humans; Mutation; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; RNA, Viral; Selection, Genetic; Viremia	2004
Early virological failure in treatment-naive HIV-infected adults receiving didanosine and tenofovir plus efavirenz or nevirapine. AIDS (London, England), 2005, Jan-28, Volume: 19, Issue:2 Topics: Adenine; Adult; Aged; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Didanosine; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nevirapine; Organophosphonates; Oxazines; Reverse Transcriptase Inhibitors; RNA, Viral; Tenofovir	2005
An extremely different dysmetabolic profile between the two available nonnucleoside reverse transcriptase inhibitors: efavirenz and nevirapine. Journal of acquired immune deficiency syndromes (1999), 2005, Feb-01, Volume: 38, Issue:2 Topics: Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Blood Glucose; Cross-Sectional Studies; Cyclopropanes; HIV Infections; Humans; Lipids; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors	2005
Influence of liver fibrosis on highly active antiretroviral therapy-associated hepatotoxicity in patients with HIV and hepatitis C virus coinfection. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Feb-15, Volume: 40, Issue:4 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Chemical and Drug Induced Liver Injury; Cyclopropanes; Female; Hepacivirus; Hepatitis C; HIV Infections; HIV-1; Humans; Liver Cirrhosis; Liver Diseases; Male; Middle Aged; Nevirapine; Oxazines; Prospective Studies; Reverse Transcriptase Inhibitors; Severity of Illness Index	2005
Top stories of 2004. Nevirapine and efavirenz: similar efficacy, different toxicities, and better separately than combined. AIDS clinical care, 2005, Volume: 17, Issue:1 Topics: Alkynes; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; Humans; Multicenter Studies as Topic; Nevirapine; Oxazines; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors	2005
Inhibition of phosphorolysis catalyzed by HIV-1 reverse transcriptase is responsible for the synergy found in combinations of 3'-azido-3'-deoxythymidine with nonnucleoside inhibitors. Biochemistry, 2005, Mar-08, Volume: 44, Issue:9 Topics: Alkynes; Benzoxazines; Binding Sites; Catalysis; Cyclopropanes; Dideoxynucleotides; DNA Primers; Drug Combinations; Drug Synergism; Enzyme Stability; HIV Reverse Transcriptase; Nevirapine; Oxazines; Phosphoric Acids; Pyridones; Reverse Transcriptase Inhibitors; Templates, Genetic; Thymine Nucleotides; Zidovudine	2005
Simple and simultaneous determination of the hiv-protease inhibitors amprenavir, atazanavir, indinavir, lopinavir, nelfinavir, ritonavir and saquinavir plus M8 nelfinavir metabolite and the nonnucleoside reverse transcriptase inhibitors efavirenz and nevi Therapeutic drug monitoring, 2005, Volume: 27, Issue:2 Topics: Alkynes; Atazanavir Sulfate; Benzoxazines; Calibration; Carbamates; Chromatography, Liquid; Cyclopropanes; Drug Stability; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lopinavir; Nelfinavir; Nevirapine; Oligopeptides; Oxazines; Pyridines; Pyrimidinones; Reproducibility of Results; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Specimen Handling; Spectrophotometry, Ultraviolet; Sulfonamides	2005
The non-nukes. Sustiva. Viramune. The two major players. Positively aware : the monthly journal of the Test Positive Aware Network, 2005,Winter, Volume: Spec No Topics: Alkynes; Benzoxazines; Cyclopropanes; Drug Interactions; HIV Infections; HIV Protease Inhibitors; Humans; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors	2005
Influence of CYP2B6 polymorphism on plasma and intracellular concentrations and toxicity of efavirenz and nevirapine in HIV-infected patients. Pharmacogenetics and genomics, 2005, Volume: 15, Issue:1 Topics: Adult; Alkynes; Alleles; Anti-HIV Agents; Aryl Hydrocarbon Hydroxylases; Benzoxazines; Cyclopropanes; Cytochrome P-450 CYP2B6; Female; Genotype; HIV Infections; HIV Seropositivity; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Nevirapine; Odds Ratio; Oxazines; Oxidoreductases, N-Demethylating; Pharmacogenetics; Polymorphism, Genetic; Protein Isoforms; Regression Analysis; Time Factors	2005
Rare one and two amino acid inserts adjacent to codon 103 of the HIV-1 reverse transcriptase (RT) affect susceptibility to non-nucleoside RT inhibitors. Antiviral therapy, 2005, Volume: 10, Issue:2 Topics: Alkynes; Benzoxazines; Cell Line; Codon; Cyclopropanes; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Models, Molecular; Mutation; Nevirapine; Nucleosides; Oxazines; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase	2005
The molecular basis of resilience to the effect of the Lys103Asn mutation in non-nucleoside HIV-1 reverse transcriptase inhibitors studied by targeted molecular dynamics simulations. Journal of the American Chemical Society, 2005, May-25, Volume: 127, Issue:20 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Binding Sites; Computer Simulation; Cyclopropanes; HIV Reverse Transcriptase; Models, Molecular; Mutagenesis, Site-Directed; Nevirapine; Nitriles; Oxazines; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thermodynamics	2005
Efficacy of highly active antiretroviral therapy in HIV-infected children participating in Thailand's National Access to Antiretroviral Program. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Jul-01, Volume: 41, Issue:1 Topics: Adolescent; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Child; Child, Preschool; Cyclopropanes; Drug Therapy, Combination; Female; Health Services Accessibility; HIV Infections; HIV-1; Humans; Male; National Health Programs; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Thailand; Treatment Outcome; Viral Load	2005
[Efficacy of anti-HIV treatment and drug-resistance mutations in some parts of China]. Zhonghua yi xue za zhi, 2005, Mar-23, Volume: 85, Issue:11 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Mutation; Nevirapine; Oxazines; Stavudine; Viral Load	2005
HIV-1 intermittent viraemia in patients treated by non-nucleoside reverse transcriptase inhibitor-based regimen. AIDS (London, England), 2005, Jul-01, Volume: 19, Issue:10 Topics: Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Female; HIV Infections; HIV Reverse Transcriptase; Humans; Male; Middle Aged; Nevirapine; Oxazines; Retrospective Studies; Reverse Transcriptase Inhibitors; Viral Load; Viremia	2005
Are adverse events of nevirapine and efavirenz related to plasma concentrations? Antiviral therapy, 2005, Volume: 10, Issue:4 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Cyclopropanes; Dose-Response Relationship, Drug; Drug Therapy, Combination; Exanthema; Female; HIV Infections; Humans; Male; Mental Disorders; Middle Aged; Nevirapine; Odds Ratio; Oxazines	2005
Determination of nevirapine and efavirenz in plasma using GC/MS in selected ion monitoring mode. Therapeutic drug monitoring, 2005, Volume: 27, Issue:4 Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Calibration; Cyclopropanes; Dose-Response Relationship, Drug; Drug Monitoring; Gas Chromatography-Mass Spectrometry; HIV Infections; Humans; Ions; Lamivudine; Molecular Structure; Nevirapine; Oxazines; Reproducibility of Results	2005
Antiretroviral therapy in HIV-1 infected children. Indian pediatrics, 2005, Volume: 42, Issue:8 Topics: Adolescent; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Child; Child, Preschool; Cyclopropanes; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; India; Male; Nevirapine	2005
Study of MMLV RT- binding with DNA using surface plasmon resonance biosensor. Acta biochimica et biophysica Sinica, 2005, Volume: 37, Issue:9 Topics: Alkynes; Benzoxazines; Cyclopropanes; DNA; DNA Damage; DNA Primers; DNA, Single-Stranded; Kinetics; Moloney murine leukemia virus; Nevirapine; Oxazines; Protein Binding; Protein Structure, Tertiary; Quercetin; Reverse Transcriptase Inhibitors; Ribonuclease H; RNA-Directed DNA Polymerase; Sensitivity and Specificity; Surface Plasmon Resonance; Templates, Genetic	2005
Triple nucleoside reverse transcriptase inhibitor- vs. nonnucleoside reverse transcriptase inhibitor-containing regimens as first-line therapy: efficacy and durability in a prospective cohort of French HIV-infected patients. HIV medicine, 2005, Volume: 6, Issue:6 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cohort Studies; Cyclopropanes; Dideoxynucleosides; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Oxazines; Prospective Studies; Reverse Transcriptase Inhibitors; Treatment Failure; Treatment Outcome; Viral Load; Zidovudine	2005
Assessment of drug-drug interactions between tenofovir disoproxil fumarate and the nonnucleoside reverse transcriptase inhibitors nevirapine and efavirenz in HIV-infected patients. Journal of acquired immune deficiency syndromes (1999), 2006, Jan-01, Volume: 41, Issue:1 Topics: Adenine; Administration, Oral; Alkynes; Benzoxazines; Cyclopropanes; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Nevirapine; Organophosphonates; Oxazines; Retrospective Studies; Reverse Transcriptase Inhibitors; Tenofovir	2006
Antiretroviral treatment in the Northern Cape. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2005, Volume: 95, Issue:11 Topics: Adolescent; Alkynes; Anti-Retroviral Agents; Benzoxazines; CD4 Lymphocyte Count; Child; Child, Preschool; Cyclopropanes; HIV Infections; Humans; Infant; Lamivudine; Lopinavir; Nevirapine; Oxazines; Pyrimidinones; Ritonavir; South Africa; Stavudine; Viral Load	2005
[Efavirenz--comprehensive status of studies]. MMW Fortschritte der Medizin, 2005, Apr-25, Volume: 147 Spec No 1 Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; HIV Infections; Humans; Lopinavir; Nevirapine; Oxazines; Pyrimidinones; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Treatment Outcome; Viral Load	2005
HIV-1 reverse transcriptase gene 103K/N and 184M/V combinations in tandem: detection and quantification of HIV-1 populations in the CD45RO+ T-cell compartment by a double-ARMS real-time PCR assay. Journal of acquired immune deficiency syndromes (1999), 2006, Feb-01, Volume: 41, Issue:2 Topics: Adult; Aged; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Cross-Sectional Studies; Cyclopropanes; Genes, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Immunologic Memory; Lamivudine; Leukocyte Common Antigens; Male; Middle Aged; Mutation; Nevirapine; Oxazines; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; T-Lymphocytes; Viral Load	2006
Pharmacokinetic parameters of nevirapine and efavirenz in relation to antiretroviral efficacy. AIDS research and human retroviruses, 2006, Volume: 22, Issue:3 Topics: Adult; Alkynes; Anti-HIV Agents; Area Under Curve; Benzoxazines; Cyclopropanes; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Nevirapine; Oxazines; Patient Compliance; Proportional Hazards Models; Prospective Studies; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; RNA, Viral; ROC Curve; Stavudine	2006
Phenotypic drug resistance patterns in subtype A HIV-1 clones with nonnucleoside reverse transcriptase resistance mutations. AIDS research and human retroviruses, 2006, Volume: 22, Issue:3 Topics: Alkynes; Amino Acid Substitution; Anti-HIV Agents; Benzoxazines; Clone Cells; Cyclopropanes; Delavirdine; Drug Resistance, Viral; Female; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Nevirapine; Oxazines; Polymorphism, Genetic; Reverse Transcriptase Inhibitors	2006
Reverse transcriptase mutations 118I, 208Y, and 215Y cause HIV-1 hypersusceptibility to non-nucleoside reverse transcriptase inhibitors. AIDS (London, England), 2006, Apr-24, Volume: 20, Issue:7 Topics: Alkynes; Benzoxazines; Codon; Cyclopropanes; Delavirdine; Drug Resistance, Viral; HIV-1; Mutation; Nevirapine; Oxazines; Phenotype; Recombination, Genetic; Reverse Transcriptase Inhibitors; Virus Replication	2006
Biosensor-based kinetic characterization of the interaction between HIV-1 reverse transcriptase and non-nucleoside inhibitors. Journal of medicinal chemistry, 2006, Apr-20, Volume: 49, Issue:8 Topics: Alkynes; Benzoxazines; Binding Sites; Biosensing Techniques; Cyclopropanes; Delavirdine; Enzyme Activation; HIV Reverse Transcriptase; Kinetics; Molecular Structure; Nevirapine; Oxazines; Protein Conformation; Pyridines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Time Factors; Urea	2006
Nonnucleoside reverse transcriptase inhibitor fold change or plasma concentration as a predictor of virological response over 48 weeks in highly treatment experienced HIV-positive individuals. AIDS research and human retroviruses, 2006, Volume: 22, Issue:4 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cohort Studies; Cyclopropanes; Follow-Up Studies; HIV Seropositivity; HIV-1; Humans; Linear Models; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Treatment Outcome	2006
Ritonavir, saquinavir, and efavirenz, but not nevirapine, inhibit bile acid transport in human and rat hepatocytes. The Journal of pharmacology and experimental therapeutics, 2006, Volume: 318, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alkynes; Animals; Anti-HIV Agents; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Benzoxazines; Biological Transport; Cells, Cultured; Child; Cyclopropanes; Hepatocytes; Humans; Male; Middle Aged; Nevirapine; Organic Anion Transporters; Organic Anion Transporters, Sodium-Dependent; Oxazines; Rats; Ritonavir; Saquinavir; Symporters; Taurocholic Acid	2006
Influence of tenofovir, nevirapine and efavirenz on ritonavir-boosted atazanavir pharmacokinetics in HIV-infected patients. European journal of clinical pharmacology, 2006, Volume: 62, Issue:7 Topics: Adenine; Adult; Alkynes; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Cyclopropanes; Drug Interactions; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Male; Nevirapine; Oligopeptides; Organophosphonates; Oxazines; Pyridines; Retrospective Studies; Reverse Transcriptase Inhibitors; Ritonavir; Tenofovir	2006
Switch from efavirenz to nevirapine associated with resolution of efavirenz-related neuropsychiatric adverse events and improvement in lipid profiles. AIDS patient care and STDs, 2006, Volume: 20, Issue:8 Topics: Adult; Alkynes; Benzoxazines; Cyclopropanes; Dyslipidemias; Female; HIV Infections; Humans; Lipids; Male; Mental Disorders; Middle Aged; Nevirapine; Oxazines; Retrospective Studies; Reverse Transcriptase Inhibitors	2006
Plasma lipid concentrations after 1.5 years of exposure to nevirapine or efavirenz together with stavudine and lamivudine. HIV medicine, 2006, Volume: 7, Issue:6 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cholesterol; Cyclopropanes; Drug Therapy, Combination; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Lipids; Lipoproteins; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Stavudine; Triglycerides	2006
Incidence and risk factors of rash associated with efavirenz in HIV-infected patients with preceding nevirapine-associated rash. HIV medicine, 2006, Volume: 7, Issue:6 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cohort Studies; Cyclopropanes; Exanthema; Female; HIV Infections; Humans; Incidence; Male; Middle Aged; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Risk Factors	2006
Drug transporter and metabolizing enzyme gene variants and nonnucleoside reverse-transcriptase inhibitor hepatotoxicity. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006, Sep-15, Volume: 43, Issue:6 Topics: Adult; Alkynes; Anti-HIV Agents; Aryl Hydrocarbon Hydroxylases; Benzoxazines; Case-Control Studies; Chemical and Drug Induced Liver Injury; Cyclopropanes; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Genes, MDR; Genetic Variation; Genotype; HIV Infections; HIV-1; Humans; Liver; Liver Diseases; Male; Nevirapine; Oxazines; Oxidoreductases, N-Demethylating; Reverse Transcriptase Inhibitors	2006
Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers. The Journal of pharmacology and experimental therapeutics, 2007, Volume: 320, Issue:1 Topics: Alkynes; Animals; Aryl Hydrocarbon Hydroxylases; Benzoxazines; Carbamazepine; Cells, Cultured; Constitutive Androstane Receptor; Cyclopropanes; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Gene Expression Regulation, Enzymologic; Hepatocytes; Humans; Mice; Nevirapine; Oxazines; Oxidoreductases, N-Demethylating; Pregnane X Receptor; Protein Transport; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Transcription Factors; Transcriptional Activation	2007
Switch from a first virologically effective protease inhibitor-containing regimen to a regimen containing efavirenz, nevirapine or abacavir. AIDS (London, England), 2006, Oct-24, Volume: 20, Issue:16 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Dideoxynucleosides; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Male; Middle Aged; Nevirapine; Oxazines; Prospective Studies; Reverse Transcriptase Inhibitors; Risk Factors; Treatment Outcome; Viral Load	2006
An isocratic liquid chromatography method for determining HIV non-nucleoside reverse transcriptase inhibitor and protease inhibitor concentrations in human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Apr-01, Volume: 848, Issue:2 Topics: Alkynes; Atazanavir Sulfate; Benzoxazines; Carbamates; Chromatography, High Pressure Liquid; Cyclopropanes; Furans; HIV Protease Inhibitors; Humans; Indinavir; Lopinavir; Nelfinavir; Nevirapine; Oligopeptides; Pyridines; Pyrimidinones; Reproducibility of Results; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Spectrophotometry, Ultraviolet; Sulfonamides	2007
Nevirapine versus efavirenz in 742 patients: no link of liver toxicity with female sex, and a baseline CD4 cell count greater than 250 cells/microl. AIDS (London, England), 2006, Nov-14, Volume: 20, Issue:17 Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Chemical and Drug Induced Liver Injury; Cyclopropanes; Female; HIV Infections; Humans; Male; Nevirapine	2006
Potent nonnucleoside reverse transcriptase inhibitors target HIV-1 Gag-Pol. PLoS pathogens, 2006, Volume: 2, Issue:11 Topics: Alkynes; Anti-HIV Agents; Antiviral Agents; Base Sequence; Benzoxazines; Cyclopropanes; Fusion Proteins, gag-pol; HeLa Cells; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Sequence Data; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Two-Hybrid System Techniques; Virus Replication; Zidovudine	2006
Comparative biological and clinical outcomes after a switch from a virologically unsuccessful first protease inhibitor-containing antiretroviral combination to a 3-drug regimen containing efavirenz, nevirapine, or abacavir. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2007, Jan-01, Volume: 44, Issue:1 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Male; Nevirapine; Oxazines; Protease Inhibitors; Reverse Transcriptase Inhibitors; Treatment Outcome; Viral Load; Virus Replication	2007
A new methodology for the simulation of flexible protein-ligand interactions. Journal of molecular graphics & modelling, 2007, Volume: 26, Issue:1 Topics: Alkynes; Benzoxazines; Computer Simulation; Crystallography, X-Ray; Cyclopropanes; HIV Reverse Transcriptase; Ligands; Models, Molecular; Nevirapine; Point Mutation; Protein Conformation; Proteins; Reverse Transcriptase Inhibitors; Thermodynamics	2007
High-performance liquid chromatography assay for the determination of the HIV-protease inhibitor tipranavir in human plasma in combination with nine other antiretroviral medications. Journal of pharmaceutical and biomedical analysis, 2007, Mar-12, Volume: 43, Issue:4 Topics: Alkynes; Anti-HIV Agents; Atazanavir Sulfate; Benzoxazines; Carbamates; Chromatography, High Pressure Liquid; Cyclopropanes; Drug Stability; Furans; HIV Protease Inhibitors; Humans; Indinavir; Lopinavir; Molecular Structure; Nelfinavir; Nevirapine; Oligopeptides; Oxazines; Pyridines; Pyrimidinones; Pyrones; Reproducibility of Results; Ritonavir; Saquinavir; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Sulfonamides; Time Factors	2007
Clinical toxicity of highly active antiretroviral therapy in a home-based AIDS care program in rural Uganda. Journal of acquired immune deficiency syndromes (1999), 2007, Apr-01, Volume: 44, Issue:4 Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Chemical and Drug Induced Liver Injury; Cyclopropanes; Exanthema; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Multivariate Analysis; Nevirapine; Pancreatitis; Peripheral Nervous System Diseases; Proportional Hazards Models; Rural Health; Stavudine; Survival Analysis; Uganda	2007
Influence of liver fibrosis stage on plasma levels of antiretroviral drugs in HIV-infected patients with chronic hepatitis C. The Journal of infectious diseases, 2007, Apr-01, Volume: 195, Issue:7 Topics: Adult; Alkynes; Anti-HIV Agents; Atazanavir Sulfate; Benzoxazines; Cyclopropanes; Drug Monitoring; Female; Hepatitis C, Chronic; HIV Infections; Humans; Liver Cirrhosis; Lopinavir; Male; Nevirapine; Oligopeptides; Oxazines; Pyridines; Pyrimidinones; Ritonavir; Severity of Illness Index	2007
Nevirapine versus efavirenz based antiretroviral treatment in naive Indian patients: comparison of effectiveness in clinical cohort. The Journal of the Association of Physicians of India, 2006, Volume: 54 Topics: Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; India; Male; Nevirapine; Oxazines; Prospective Studies; Reverse Transcriptase Inhibitors	2006
Methodological standards in non-inferiority AIDS trials: moving from adherence to compliance: response. BMC medical research methodology, 2007, Mar-02, Volume: 7 Topics: Acquired Immunodeficiency Syndrome; Alkynes; Anti-HIV Agents; Benzoxazines; Clinical Trials as Topic; Cyclopropanes; Humans; Nevirapine; Oxazines; Patient Compliance; Research Design	2007
Association of serum lipid levels with HIV serostatus, specific antiretroviral agents, and treatment regimens. Journal of acquired immune deficiency syndromes (1999), 2007, May-01, Volume: 45, Issue:1 Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Black People; Cholesterol; Cross-Sectional Studies; Cyclopropanes; Didanosine; Dideoxynucleosides; Drug Therapy, Combination; Fasting; Female; Hispanic or Latino; HIV Infections; HIV Protease Inhibitors; HIV Seronegativity; HIV Seropositivity; HIV-1; Humans; Indinavir; Lamivudine; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Multivariate Analysis; Nelfinavir; Nevirapine; Organophosphonates; Ritonavir; Stavudine; Tenofovir; Triglycerides; United States; White People	2007
Discontinuation of non-nucleoside reverse transcriptase inhibitor-based highly active antiretroviral therapy due to nucleoside analogue reverse transcriptase inhibitor-related metabolic toxicity. International journal of STD & AIDS, 2007, Volume: 18, Issue:5 Topics: Adolescent; Adult; Aged; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cohort Studies; Cyclopropanes; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; Humans; Male; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; United Kingdom	2007
Emergence of NNRTI drug resistance mutations after single-dose nevirapine exposure in HIV type 1 subtype C-infected infants in India. AIDS research and human retroviruses, 2007, Volume: 23, Issue:5 Topics: Alkynes; Benzoxazines; Cyclopropanes; Delavirdine; Drug Resistance, Viral; Feasibility Studies; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; India; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Molecular Sequence Data; Mutation; Nevirapine; Polymerase Chain Reaction; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors	2007
Dynamics of 103K/N and 184M/V HIV-1 drug resistant populations: relative comparison in plasma virus RNA versus CD45RO+T cell proviral DNA. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2007, Volume: 39, Issue:3 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Leukocyte Common Antigens; Mutation; Nevirapine; Nucleic Acid Amplification Techniques; Proviruses; Reverse Transcriptase Inhibitors; RNA, Viral; T-Lymphocytes; Viremia	2007
[Efficacy and tolerance of non nucleosidic reverse transcriptase inhibitors containing tritherapy in HIV-1 infection]. Dakar medical, 2005, Volume: 50, Issue:3 Topics: Adolescent; Adult; Aged; Alkynes; Benzoxazines; Cyclopropanes; Drug Combinations; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nevirapine; Retrospective Studies; Reverse Transcriptase Inhibitors	2005
Probing nonnucleoside inhibitor-induced active-site distortion in HIV-1 reverse transcriptase by transient kinetic analyses. Protein science : a publication of the Protein Society, 2007, Volume: 16, Issue:8 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Binding Sites; Catalysis; Cyclopropanes; Delavirdine; HIV Reverse Transcriptase; Kinetics; Models, Molecular; Nevirapine; Protein Conformation; Reverse Transcriptase Inhibitors; Thymine Nucleotides	2007
Effect of anticoagulants on plasma nevirapine and efavirenz concentrations. Therapeutic drug monitoring, 2007, Volume: 29, Issue:5 Topics: Adult; Alkynes; Anti-HIV Agents; Anticoagulants; Benzoxazines; Cyclopropanes; Drug Monitoring; Edetic Acid; Female; Heparin; HIV Infections; Humans; Male; Middle Aged; Nevirapine; Specimen Handling	2007
Monitoring the development of non-nucleoside reverse transcriptase inhibitor-associated resistant HIV-1 using an electrochemiluminescence-based reverse transcriptase polymerase assay. Analytical biochemistry, 2008, Mar-01, Volume: 374, Issue:1 Topics: Alkynes; Benzoxazines; Cell Line; Cyclopropanes; Delavirdine; Drug Resistance, Viral; Electrochemistry; HIV-1; Humans; Luminescent Measurements; Nevirapine; Organometallic Compounds; Reverse Transcriptase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA-Directed DNA Polymerase	2008
Improved interpretation of genotypic changes in the HIV-1 reverse transcriptase coding region that determine the virological response to didanosine. The Journal of infectious diseases, 2007, Dec-01, Volume: 196, Issue:11 Topics: Acquired Immunodeficiency Syndrome; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Didanosine; Female; Genotype; HIV Reverse Transcriptase; HIV-1; Humans; Lopinavir; Male; Middle Aged; Mutation; Nelfinavir; Nevirapine; Pyrimidinones; Reverse Transcriptase Inhibitors; RNA, Viral; Salvage Therapy	2007
CYP2B6 genetic variants are associated with nevirapine pharmacokinetics and clinical response in HIV-1-infected children. AIDS (London, England), 2007, Oct-18, Volume: 21, Issue:16 Topics: Alkynes; Antiretroviral Therapy, Highly Active; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzoxazines; CD4 Lymphocyte Count; Child, Preschool; Cyclopropanes; Cytochrome P-450 CYP2B6; Female; Gene Frequency; Genotype; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Male; Multivariate Analysis; Nevirapine; Oxidoreductases, N-Demethylating; Polymorphism, Genetic; Retrospective Studies; Reverse Transcriptase Inhibitors; Treatment Outcome	2007
Energetic effects for observed and unobserved HIV-1 reverse transcriptase mutations of residues L100, V106, and Y181 in the presence of nevirapine and efavirenz. Bioorganic & medicinal chemistry letters, 2008, Feb-01, Volume: 18, Issue:3 Topics: Alkynes; Amino Acid Substitution; Anti-HIV Agents; Benzoxazines; Computer Simulation; Cyclopropanes; Drug Resistance; Drug Resistance, Viral; HIV Reverse Transcriptase; Humans; Leucine; Models, Molecular; Molecular Structure; Mutation, Missense; Nevirapine; Reverse Transcriptase Inhibitors; Thermodynamics; Tyrosine; Valine	2008
Association between exposure to nevirapine and reduced liver fibrosis progression in patients with HIV and hepatitis C virus coinfection. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008, Jan-01, Volume: 46, Issue:1 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cross-Sectional Studies; Cyclopropanes; Disease Progression; Female; Hepatitis C; HIV Infections; Humans; Interferon-alpha; Liver Cirrhosis; Male; Nevirapine; Protease Inhibitors; Retrospective Studies; Reverse Transcriptase Inhibitors; Ribavirin; Viral Load	2008
Comparison of genotypic resistance profiles and virological response between patients starting nevirapine and efavirenz in EuroSIDA. AIDS (London, England), 2008, Jan-30, Volume: 22, Issue:3 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cohort Studies; Cyclopropanes; Drug Resistance, Viral; Europe; Female; Genotype; HIV Infections; HIV-1; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Mutation; Nevirapine; Proportional Hazards Models; Reverse Transcriptase Inhibitors; Treatment Failure; Treatment Outcome	2008
Patterns and predictors of the use of different antiretroviral drug regimens at treatment initiation in the UK. HIV medicine, 2008, Volume: 9, Issue:1 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Administration Schedule; Female; HIV Infections; Humans; Male; Nevirapine; Outpatient Clinics, Hospital; Patient Compliance; Practice Guidelines as Topic; Practice Patterns, Physicians'; Protease Inhibitors; Reverse Transcriptase Inhibitors; Time Factors; United Kingdom	2008
Lipodystrophy and metabolic changes in HIV-infected children on non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy. Antiviral therapy, 2007, Volume: 12, Issue:8 Topics: Adolescent; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Child; Child, Preschool; Cyclopropanes; Female; HIV Infections; HIV-1; Humans; Hypercholesterolemia; Hyperglycemia; Hypertriglyceridemia; Lamivudine; Lipodystrophy; Male; Nevirapine; Prevalence; Reverse Transcriptase Inhibitors; Stavudine; Thailand	2007
Impact of nevirapine or efavirenz co-administration on ritonavir-boosted amprenavir pharmacokinetics in HIV-infected patients. Fundamental & clinical pharmacology, 2008, Volume: 22, Issue:1 Topics: Adult; Alkynes; Anti-HIV Agents; Bayes Theorem; Benzoxazines; Carbamates; Cyclopropanes; Drug Therapy, Combination; Female; France; Furans; HIV Infections; Humans; Male; Models, Biological; Nevirapine; Organophosphates; Reverse Transcriptase Inhibitors; Ritonavir; Sulfonamides	2008
Determination of abacavir, amprenavir, didanosine, efavirenz, nevirapine, and stavudine concentration in human plasma by MALDI-TOF/TOF. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008, Mar-01, Volume: 863, Issue:2 Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Carbamates; Cyclopropanes; Didanosine; Dideoxynucleosides; Drug Monitoring; Feasibility Studies; Furans; Humans; Molecular Structure; Nevirapine; Reverse Transcriptase Inhibitors; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry, Ultraviolet; Stavudine; Sulfonamides	2008
Impact of CYP2B6 983T>C polymorphism on non-nucleoside reverse transcriptase inhibitor plasma concentrations in HIV-infected patients. The Journal of antimicrobial chemotherapy, 2008, Volume: 61, Issue:4 Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alkynes; Aryl Hydrocarbon Hydroxylases; Benzoxazines; Black People; Body Mass Index; Chromatography, High Pressure Liquid; Cyclopropanes; Cytochrome P-450 CYP2B6; Female; Gene Frequency; HIV Infections; Humans; Male; Middle Aged; Multivariate Analysis; Nevirapine; Oxidoreductases, N-Demethylating; Polymerase Chain Reaction; Polymorphism, Genetic; Reverse Transcriptase Inhibitors; White People	2008
Adaptation of antiretroviral therapy in human immunodeficiency virus infection with central nervous system involvement. Journal of neurovirology, 2008, Volume: 14, Issue:1 Topics: Adenine; Adult; AIDS Dementia Complex; Alkynes; Anti-HIV Agents; Anticonvulsants; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Cerebrospinal Fluid; Cyclopropanes; Didanosine; HIV-1; Humans; Indinavir; Lamivudine; Male; Nelfinavir; Nevirapine; Oligopeptides; Organophosphonates; Pyridines; Ritonavir; Seizures; Stavudine; Tenofovir; Viral Load; Virus Replication; Zidovudine	2008
HLA-DRB101 associated with cutaneous hypersensitivity induced by nevirapine and efavirenz. AIDS (London, England), 2008, Feb-19, Volume: 22, Issue:4* Topics: Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Eruptions; Female; HIV Infections; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Male; Middle Aged; Nevirapine; Prospective Studies	2008
Association of antiretroviral therapy with fibrinogen levels in HIV-infection. AIDS (London, England), 2008, Mar-30, Volume: 22, Issue:6 Topics: Adult; Alkynes; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Case-Control Studies; Cyclopropanes; Female; Fibrinogen; HIV Infections; Humans; Indinavir; Linear Models; Male; Nevirapine; Protease Inhibitors; Reverse Transcriptase Inhibitors; Ritonavir	2008
[HIV-1 genotypic resistance profiles in children failing highly active antiretroviral therapy]. Zhonghua yi xue za zhi, 2007, Dec-11, Volume: 87, Issue:46 Topics: Acquired Immunodeficiency Syndrome; Adolescent; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Child; Child, Preschool; China; Cyclopropanes; Delavirdine; Drug Resistance, Viral; Genotype; HIV-1; Humans; Mutation; Nevirapine; Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Viral Load; Zidovudine	2007
Changes in lipid profile over 24 months among adults on first-line highly active antiretroviral therapy in the home-based AIDS care program in rural Uganda. Journal of acquired immune deficiency syndromes (1999), 2008, Mar-01, Volume: 47, Issue:3 Topics: Acquired Immunodeficiency Syndrome; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cardiovascular Diseases; CD4 Lymphocyte Count; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cyclopropanes; Female; Home Care Services; Humans; Lipids; Male; Middle Aged; Nevirapine; Risk Factors; Rural Health; Time Factors; Triglycerides; Uganda	2008
Standard-dose efavirenz vs. standard-dose nevirapine in antiretroviral regimens among HIV-1 and tuberculosis co-infected patients who received rifampicin. HIV medicine, 2008, Volume: 9, Issue:5 Topics: Adult; AIDS-Related Opportunistic Infections; Alkynes; Antitubercular Agents; Benzoxazines; CD4 Lymphocyte Count; Cohort Studies; Cyclopropanes; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Male; Nevirapine; Retrospective Studies; Reverse Transcriptase Inhibitors; Rifampin; Treatment Outcome; Tuberculosis; Viral Load	2008
[Polyneuropathies in patients treated with HAART in Bobo-Dioulasso hospital, Burkina Faso]. Bulletin de la Societe de pathologie exotique (1990), 2008, Volume: 101, Issue:1 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Burkina Faso; CD4 Lymphocyte Count; Cyclopropanes; Female; Follow-Up Studies; Foot Diseases; HIV Infections; Humans; Hypesthesia; Lamivudine; Male; Middle Aged; Nevirapine; Pain; Paresthesia; Polyneuropathies; Reflex, Abnormal; Sensory Thresholds; Stavudine; Vibration	2008
Long-term efficacy and tolerance of efavirenz- and nevirapine-containing regimens in adult HIV type 1 Senegalese patients. AIDS research and human retroviruses, 2008, Volume: 24, Issue:6 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cohort Studies; Cyclopropanes; Drug Tolerance; Female; HIV Infections; HIV-1; Humans; Logistic Models; Male; Nevirapine; Patient Selection; Poisson Distribution; Proportional Hazards Models; Reverse Transcriptase Inhibitors; Senegal; Time Factors; Treatment Outcome; Viral Load	2008
Selective targeting of the HIV-1 reverse transcriptase catalytic complex through interaction with the "primer grip" region by pyrrolobenzoxazepinone non-nucleoside inhibitors correlates with increased activity towards drug-resistant mutants. Biochemical pharmacology, 2008, Jul-15, Volume: 76, Issue:2 Topics: 3T3 Cells; Alkynes; Animals; Azepines; Benzoxazines; Catalysis; Cell Line; Cells, Cultured; Cyclopropanes; DNA-Directed DNA Polymerase; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Leukocytes, Mononuclear; Mice; Models, Molecular; Mutation; Nevirapine; Reverse Transcriptase Inhibitors	2008
[Evaluation of antiretroviral therapy in HIV-infected adults in the Department of Haematology, University Hospital of Brazzavllle, Congo]. Bulletin de la Societe de pathologie exotique (1990), 2008, Volume: 101, Issue:2 Topics: Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Congo; Cyclopropanes; Didanosine; Drug Evaluation; Drug Therapy, Combination; Female; Hematology; HIV Infections; Hospital Departments; Hospitals, University; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Retrospective Studies; Stavudine; Treatment Outcome; Viral Load; Zidovudine	2008
Efavirenz replacement by immediate full-dose nevirapine is safe in HIV-1-infected patients in Cambodia. HIV medicine, 2008, Volume: 9, Issue:7 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cambodia; Cyclopropanes; Exanthema; Female; Hepatitis; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nevirapine; Retrospective Studies; Stevens-Johnson Syndrome; Young Adult	2008
Prevalence of etravirine-associated mutations in clinical samples with resistance to nevirapine and efavirenz. The Journal of antimicrobial chemotherapy, 2008, Volume: 62, Issue:5 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Mutation, Missense; Nevirapine; Nitriles; Pyridazines; Pyrimidines	2008
Outcomes of nevirapine- and efavirenz-based antiretroviral therapy when coadministered with rifampicin-based antitubercular therapy. JAMA, 2008, Aug-06, Volume: 300, Issue:5 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antitubercular Agents; Benzoxazines; Cyclopropanes; Drug Interactions; Female; HIV Infections; Humans; Male; Nevirapine; Rifampin; South Africa; Treatment Failure; Treatment Outcome; Tuberculosis; Viral Load	2008
Hepatotoxicity in patients prescribed efavirenz or nevirapine. European journal of medical research, 2008, Jul-28, Volume: 13, Issue:7 Topics: Adult; Alkynes; Benzoxazines; CD4-Positive T-Lymphocytes; Chemical and Drug Induced Liver Injury; Cyclopropanes; Female; Hepacivirus; Hepatitis B virus; HIV Infections; Humans; Liver; Male; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; Risk Factors	2008
Factors influencing efavirenz and nevirapine plasma concentration: effect of ethnicity, weight and co-medication. Antiviral therapy, 2008, Volume: 13, Issue:5 Topics: Adult; Alkynes; Anti-HIV Agents; Antitubercular Agents; Benzoxazines; Black People; Body Weight; Cyclopropanes; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; Rifampin; Viral Load; White People	2008
Effects of the HIV treatment drugs nevirapine and efavirenz on brain creatine kinase activity. Metabolic brain disease, 2008, Volume: 23, Issue:4 Topics: Alkynes; Animals; Anti-HIV Agents; Benzoxazines; Blood-Brain Barrier; Brain; Cerebellum; Cerebral Cortex; Creatine Kinase; Cyclopropanes; Enzyme Inhibitors; Hippocampus; Male; Mice; Neostriatum; Nevirapine; Reverse Transcriptase Inhibitors	2008
Bayesian network analyses of resistance pathways against efavirenz and nevirapine. AIDS (London, England), 2008, Oct-18, Volume: 22, Issue:16 Topics: Alkynes; Anti-HIV Agents; Bayes Theorem; Benzoxazines; Cyclopropanes; Databases, Factual; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Nevirapine; Reverse Transcriptase Inhibitors; Signal Transduction	2008
Efavirenz versus nevirapine-based initial treatment of HIV infection: clinical and virological outcomes in Southern African adults. AIDS (London, England), 2008, Oct-18, Volume: 22, Issue:16 Topics: Adult; Africa, Southern; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cohort Studies; Cyclopropanes; Drug Evaluation; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nevirapine; Patient Compliance; Reverse Transcriptase Inhibitors; Treatment Failure; Treatment Outcome; Viral Load	2008
Clinical manifestations and antiretroviral management of HIV/AIDS patients with tuberculosis co-infection in Kramat 128 Hospital. Acta medica Indonesiana, 2008, Volume: 40, Issue:3 Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Alkynes; Anti-HIV Agents; Anti-Retroviral Agents; Benzoxazines; Cross-Sectional Studies; Cyclopropanes; Female; HIV Infections; Humans; Indonesia; Male; Middle Aged; Nevirapine; Outpatient Clinics, Hospital; Outpatients; Risk Factors; Treatment Outcome; Tuberculosis, Pulmonary	2008
Effects of nevirapine and efavirenz on HDL cholesterol levels and reverse cholesterol transport in mice. Atherosclerosis, 2009, Volume: 204, Issue:2 Topics: Alkynes; Animals; Anti-HIV Agents; Apolipoprotein A-I; Benzoxazines; Biological Transport; Cell Line; Cholesterol; Cholesterol, HDL; Cyclopropanes; Dietary Fats; Female; Humans; Liver; Macrophages; Mice; Mice, Knockout; Mice, Transgenic; Nevirapine; Receptors, LDL; Reverse Transcriptase Inhibitors; Time Factors; Up-Regulation	2009
Quantification of 8 HIV-protease inhibitors and 2 nonnucleoside reverse transcriptase inhibitors by ultra-performance liquid chromatography with diode array detection. Clinical chemistry, 2009, Volume: 55, Issue:1 Topics: Alkynes; Atazanavir Sulfate; Benzoxazines; Carbamates; Chromatography, High Pressure Liquid; Cyclopropanes; Furans; HIV Protease Inhibitors; Humans; Indinavir; Lopinavir; Nelfinavir; Nevirapine; Oligopeptides; Pyridines; Pyrimidinones; Pyrones; Reproducibility of Results; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Sensitivity and Specificity; Solid Phase Extraction; Sulfonamides	2009
Variability in the plasma concentration of efavirenz and nevirapine is associated with genotypic resistance after treatment interruption. Antiviral therapy, 2008, Volume: 13, Issue:7 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; DNA, Viral; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Nevirapine; Proviruses; Reverse Transcriptase Inhibitors; RNA, Viral	2008
Minority quasispecies of drug-resistant HIV-1 that lead to early therapy failure in treatment-naive and -adherent patients. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2009, Jan-15, Volume: 48, Issue:2 Topics: Adenine; Alkynes; Alleles; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; Female; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Medication Adherence; Mutation, Missense; Nevirapine; Organophosphonates; Plasma; Polymerase Chain Reaction; Selection, Genetic; Tenofovir; Treatment Failure	2009
A prospective study evaluating clinical outcomes and costs of three NNRTI-based HAART regimens in Kerala, India. Journal of clinical pharmacy and therapeutics, 2009, Volume: 34, Issue:1 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Female; HIV Infections; HIV-1; Hospitals, Teaching; Humans; India; Lamivudine; Male; Medication Adherence; Nevirapine; Prospective Studies; Stavudine; Treatment Outcome; Zidovudine	2009
Association of high T allele frequency of CYP2B6 G516T polymorphism among ethnic south Indian HIV-infected patients with elevated plasma efavirenz and nevirapine. The Journal of antimicrobial chemotherapy, 2009, Volume: 63, Issue:4 Topics: Adult; Alkynes; Anti-HIV Agents; Aryl Hydrocarbon Hydroxylases; Benzoxazines; Cyclopropanes; Cytochrome P-450 CYP2B6; Female; Gene Frequency; HIV Infections; Humans; India; Male; Middle Aged; Nevirapine; Oxidoreductases, N-Demethylating; Plasma; Point Mutation; Polymorphism, Genetic; Young Adult	2009
Switch to Viramune safe for some who can't tolerate Sustiva. Project Inform perspective, 2008, Issue:47 Topics: Alkynes; Benzoxazines; Cyclopropanes; Female; HIV Infections; Humans; Male; Nevirapine; Reverse Transcriptase Inhibitors	2008
Associations between CYP2B6 polymorphisms and pharmacokinetics after a single dose of nevirapine or efavirenz in African americans. The Journal of infectious diseases, 2009, Mar-15, Volume: 199, Issue:6 Topics: Alkynes; Anti-HIV Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Benzoxazines; Black People; Cyclopropanes; Cytochrome P-450 CYP2B6; Genotype; HIV Seronegativity; Humans; Linkage Disequilibrium; Metabolic Clearance Rate; Nevirapine; Oxidoreductases, N-Demethylating; Polymorphism, Genetic; Safety	2009
The cost-effectiveness analysis of initiating HIV/AIDS treatment with efavirenz-based regimens compared with nevirapine-based regimens in Thailand. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2008, Volume: 91 Suppl 2 Topics: Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; Cohort Studies; Cost-Benefit Analysis; Cyclopropanes; Female; HIV Infections; Humans; Male; Markov Chains; Middle Aged; Models, Economic; Nevirapine; Probability; Quality-Adjusted Life Years; Reverse Transcriptase Inhibitors; Thailand; Young Adult	2008
Predicting factors for unsuccessful switching from nevirapine to efavirenz in HIV-infected patients who developed nevirapine-associated skin rash. International journal of STD & AIDS, 2009, Volume: 20, Issue:3 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Chi-Square Distribution; Cohort Studies; Cyclopropanes; Drug Hypersensitivity; Exanthema; Female; HIV Infections; Humans; Logistic Models; Male; Nevirapine; Retrospective Studies; Risk Factors; Statistics, Nonparametric; Viral Load	2009
Safety and efficacy of nevirapine- and efavirenz-based antiretroviral treatment in adults treated for TB-HIV co-infection in Botswana. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2009, Volume: 13, Issue:3 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Botswana; CD4 Lymphocyte Count; Comorbidity; Cyclopropanes; Female; HIV; HIV Infections; Humans; Liver Function Tests; Male; Nevirapine; Retrospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Tuberculosis, Pulmonary	2009
Proinflammatory cytokine changes in clinically stable, virologically suppressed, HIV-infected patients switching from protease inhibitors to abacavir. Journal of acquired immune deficiency syndromes (1999), 2009, Apr-15, Volume: 50, Issue:5 Topics: Adiponectin; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Administration Schedule; HIV Infections; Humans; Nevirapine; Receptors, Tumor Necrosis Factor, Type II	2009
The nucleoside backbone affects durability of efavirenz- or nevirapine-based highly active antiretroviral therapy in antiretroviral-naive individuals. Journal of acquired immune deficiency syndromes (1999), 2009, Jun-01, Volume: 51, Issue:2 Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Cohort Studies; Cyclopropanes; Ethnicity; Female; HIV Infections; HIV-1; Humans; Male; Nevirapine	2009
Nonnucleoside reverse transcriptase inhibitor pharmacokinetics in a large unselected cohort of HIV-infected women. Journal of acquired immune deficiency syndromes (1999), 2009, Apr-15, Volume: 50, Issue:5 Topics: Adult; Alkynes; Anti-HIV Agents; Area Under Curve; Benzoxazines; Cohort Studies; Cyclopropanes; Dose-Response Relationship, Drug; Female; HIV Infections; Humans; Linear Models; Middle Aged; Multivariate Analysis; Nevirapine; Prospective Studies; Reverse Transcriptase Inhibitors; Time Factors; Young Adult	2009
Efavirenz and nevirapine interactions with rifampicin: resolving the dilemmas? Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2009, Jun-15, Volume: 48, Issue:12 Topics: Alkynes; Anti-Bacterial Agents; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Interactions; HIV Infections; Humans; Nevirapine; Rifampin; Tuberculosis	2009
[Establishment of pharmacological evaluation system for non-nucleoside reverse-transcriptase inhibitors resistant HIV-1]. Yao xue xue bao = Acta pharmaceutica Sinica, 2009, Volume: 44, Issue:4 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cell Line; Cyclopropanes; Delavirdine; Drug Evaluation, Preclinical; Drug Resistance, Viral; Genetic Vectors; HIV Reverse Transcriptase; HIV-1; Humans; Membrane Glycoproteins; Nevirapine; Plasmids; Point Mutation; Reverse Transcriptase Inhibitors; Stavudine; Transfection; Viral Envelope Proteins; Virion; Virus Replication; Zidovudine	2009
Dissection of regenerating T-Cell responses against tuberculosis in HIV-infected adults sensitized by Mycobacterium tuberculosis. American journal of respiratory and critical care medicine, 2009, Oct-01, Volume: 180, Issue:7 Topics: Adult; Alkynes; Analysis of Variance; Anti-HIV Agents; Anti-Retroviral Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Cytokines; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Follow-Up Studies; HIV Infections; Humans; Immunization; Lamivudine; Longitudinal Studies; Male; Middle Aged; Mycobacterium tuberculosis; Nevirapine; Stavudine; T-Lymphocytes; Tuberculosis	2009
Intracellular accumulation of efavirenz and nevirapine is independent of P-glycoprotein activity in cultured CD4 T cells and primary human lymphocytes. The Journal of antimicrobial chemotherapy, 2009, Volume: 64, Issue:5 Topics: Alkynes; Anti-HIV Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzoxazines; CD4-Positive T-Lymphocytes; Cell Line; Cells, Cultured; Cyclopropanes; Cytosol; Gene Expression Profiling; Gene Expression Regulation; Humans; Leukocytes, Mononuclear; Nevirapine	2009
Low-frequency K103N strengthens the impact of transmitted drug resistance on virologic responses to first-line efavirenz or nevirapine-based highly active antiretroviral therapy. Journal of acquired immune deficiency syndromes (1999), 2009, Volume: 52, Issue:5 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Male; Mutation; Nevirapine; Reverse Transcriptase Inhibitors; Treatment Failure; Viral Load	2009
Development of an allele-specific PCR for detection of the K65R resistance mutation in patients infected with subtype C human immunodeficiency virus type 1. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:2 Topics: Alkynes; Alleles; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Nevirapine; Polymerase Chain Reaction; Zidovudine	2010
Anti-HIV drugs nevirapine and efavirenz affect anxiety-related behavior and cognitive performance in mice. Neurotoxicity research, 2011, Volume: 19, Issue:1 Topics: Alkynes; Animals; Anti-HIV Agents; Anxiety; Benzoxazines; Cognition; Cyclopropanes; Exploratory Behavior; Male; Mice; Nevirapine	2011
Etravirine resistance associated mutations in HIV-infected patients failing efavirenz or nevirapine in the Spanish antiretroviral resistance database. AIDS (London, England), 2010, Jan-28, Volume: 24, Issue:3 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; HIV-1; Humans; Mutation; Nevirapine; Nitriles; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; Spain; Treatment Failure	2010
Treatment modification in human immunodeficiency virus-infected individuals starting combination antiretroviral therapy between 2005 and 2008. Archives of internal medicine, 2010, Jan-11, Volume: 170, Issue:1 Topics: Adenine; Adult; AIDS-Related Opportunistic Infections; Alkynes; Anti-HIV Agents; Atazanavir Sulfate; Benzoxazines; Cyclopropanes; Deoxycytidine; Dideoxynucleosides; Drug Therapy, Combination; Emtricitabine; Female; HIV Infections; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Nevirapine; Oligopeptides; Organophosphonates; Proportional Hazards Models; Prospective Studies; Pyridines; Pyrimidinones; Risk Factors; Switzerland; Tenofovir; Zidovudine	2010
HIV type 1 antiretroviral resistance mutations in subtypes B, C, and F in the City of São Paulo, Brazil. AIDS research and human retroviruses, 2010, Volume: 26, Issue:3 Topics: Alkynes; Benzoxazines; Brazil; Cohort Studies; Cyclopropanes; Darunavir; Drug Resistance, Multiple, Viral; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Mutation; Nevirapine; Nitriles; Pyridazines; Pyridines; Pyrimidines; Pyrones; Reverse Transcriptase Inhibitors; Sulfonamides; Treatment Failure; Viral Load	2010
Predicting virologic failure among HIV-1-infected children receiving antiretroviral therapy in Tanzania: a cross-sectional study. Journal of acquired immune deficiency syndromes (1999), 2010, Volume: 54, Issue:4 Topics: Adolescent; Alkynes; Anti-HIV Agents; Anti-Retroviral Agents; Benzoxazines; CD4 Antigens; CD4 Lymphocyte Count; Child; Child, Preschool; Cross-Sectional Studies; Cyclopropanes; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Infant; Male; Nevirapine; Predictive Value of Tests; Recurrence; RNA, Viral; Severity of Illness Index; Tanzania; Treatment Failure	2010
Analysis of RT sequences of subtype C HIV-type 1 isolates from indian patients at failure of a first-line treatment according to clinical and/or immunological WHO guidelines. AIDS research and human retroviruses, 2010, Volume: 26, Issue:3 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; India; Lamivudine; Molecular Sequence Data; Nevirapine; Polymorphism, Single Nucleotide; Stavudine; Treatment Failure; Zidovudine	2010
Positive and negative drug selection pressures on the N348I connection domain mutation: new insights from in vivo data. Antiviral therapy, 2010, Volume: 15, Issue:2 Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Case-Control Studies; Cyclopropanes; Databases, Genetic; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; HIV Reverse Transcriptase; HIV-1; Humans; Logistic Models; Mutation; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine	2010
Better health-related quality of life after switching from a virologically effective regimen to a regimen containing efavirenz or nevirapine. AIDS care, 2010, Volume: 22, Issue:1 Topics: Adult; Aged; Alkynes; Anxiety; Benzoxazines; Cyclopropanes; Depression; Female; France; Health Status; HIV Infections; Humans; Male; Middle Aged; Nevirapine; Prospective Studies; Quality of Life; Reverse Transcriptase Inhibitors; Surveys and Questionnaires; Treatment Outcome; Viral Load; Young Adult	2010
Pharmacokinetics of the treatment switch from efavirenz to nevirapine. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2010, Jun-01, Volume: 50, Issue:11 Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; HIV Infections; Humans; Nevirapine	2010
Constrained patterns of covariation and clustering of HIV-1 non-nucleoside reverse transcriptase inhibitor resistance mutations. The Journal of antimicrobial chemotherapy, 2010, Volume: 65, Issue:7 Topics: Alkynes; Amino Acid Substitution; Anti-HIV Agents; Benzoxazines; Cyclopropanes; DNA Mutational Analysis; Drug Resistance, Multiple, Viral; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Male; Mutation, Missense; Nevirapine; Nitriles; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors	2010
Patients infected with HIV type 1 subtype CRF01_AE and failing first-line nevirapine- and efavirenz-based regimens demonstrate considerable cross-resistance to etravirine. AIDS research and human retroviruses, 2010, Volume: 26, Issue:6 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Nevirapine; Nitriles; Pyridazines; Pyrimidines; Treatment Failure	2010
N348I in HIV-1 reverse transcriptase can counteract the nevirapine-mediated bias toward RNase H cleavage during plus-strand initiation. The Journal of biological chemistry, 2010, Aug-27, Volume: 285, Issue:35 Topics: Alkynes; Amino Acid Substitution; Benzoxazines; Cyclopropanes; DNA, Viral; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Mutation, Missense; Nevirapine; Reverse Transcriptase Inhibitors; Ribonuclease H; RNA, Viral	2010
Switching from efavirenz to nevirapine. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2010, Aug-01, Volume: 51, Issue:3 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; HIV Infections; Humans; Nevirapine; Time Factors; Treatment Failure	2010
Theoretical studies on the molecular basis of HIV-1RT/NNRTIs interactions. Journal of enzyme inhibition and medicinal chemistry, 2011, Volume: 26, Issue:1 Topics: Alkynes; Amino Acids; Benzoxazines; Binding Sites; Cyclopropanes; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Models, Biological; Molecular Dynamics Simulation; Mutation; Nevirapine; Nitriles; Protein Binding; Protein Conformation; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; Thermodynamics; Uracil; Water	2011
CYP2B6 polymorphism and nonnucleoside reverse transcriptase inhibitor plasma concentrations in Chinese HIV-infected patients. Therapeutic drug monitoring, 2010, Volume: 32, Issue:5 Topics: Adult; Aged; Alkynes; Aryl Hydrocarbon Hydroxylases; Asian People; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzoxazines; China; Chromatography, High Pressure Liquid; Cyclopropanes; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Female; Gene Frequency; Genotype; HIV Infections; Humans; Male; Mass Spectrometry; Middle Aged; Nevirapine; Oxidoreductases, N-Demethylating; Polymorphism, Genetic; Reverse Transcriptase Inhibitors	2010
A comparison of the long-term durability of nevirapine, efavirenz and lopinavir in routine clinical practice in Europe: a EuroSIDA study. HIV medicine, 2011, Volume: 12, Issue:5 Topics: Alkynes; Argentina; Benzoxazines; Cyclopropanes; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Europe; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Israel; Lopinavir; Male; Nevirapine; Prospective Studies; Pyrimidinones; Reverse Transcriptase Inhibitors; Treatment Outcome; Viral Load	2011
Differential impact of the HIV-1 non-nucleoside reverse transcriptase inhibitor mutations K103N and M230L on viral replication and enzyme function. The Journal of antimicrobial chemotherapy, 2010, Volume: 65, Issue:11 Topics: Alkynes; Amino Acid Substitution; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Mutation, Missense; Nevirapine; Nitriles; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; Virus Replication	2010
Stavudine toxicity in women is the main reason for treatment change in a 3-year prospective cohort of adult patients started on first-line antiretroviral treatment in Uganda. Journal of acquired immune deficiency syndromes (1999), 2011, Jan-01, Volume: 56, Issue:1 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Female; HIV Infections; Humans; Kaplan-Meier Estimate; Lamivudine; Male; Multivariate Analysis; Nevirapine; Prospective Studies; Risk Factors; Sex Factors; Stavudine; Uganda; Zidovudine	2011
Evaluating patients for second-line antiretroviral therapy in India: the role of targeted viral load testing. Journal of acquired immune deficiency syndromes (1999), 2010, Dec-15, Volume: 55, Issue:5 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Female; HIV; HIV Infections; Humans; India; Lamivudine; Male; Middle Aged; Nevirapine; RNA, Viral; Stavudine; Treatment Failure; Viral Load; Zidovudine	2010
Pregnancy outcomes in women exposed to efavirenz and nevirapine: an appraisal of the IeDEA West Africa and ANRS Databases, Abidjan, Côte d'Ivoire. Journal of acquired immune deficiency syndromes (1999), 2011, Feb-01, Volume: 56, Issue:2 Topics: Abortion, Induced; Abortion, Spontaneous; Adult; Africa, Western; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Female; HIV Infections; Humans; Infant, Low Birth Weight; Infant, Newborn; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Premature Birth; Retrospective Studies; Risk Assessment; Stillbirth	2011
Easier said than done: World Health Organization recommendations for prevention of mother-to-child transmission of HIV-areas of concern. AIDS research and human retroviruses, 2011, Volume: 27, Issue:8 Topics: Africa South of the Sahara; Alkynes; Anti-HIV Agents; Benzoxazines; Breast Feeding; CD4 Lymphocyte Count; Child; Cyclopropanes; Female; Flow Cytometry; Global Health; HIV; HIV Infections; Humans; Infant; Infectious Disease Transmission, Vertical; Nevirapine; Policy; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Infectious; Public Health	2011
Higher efficacy of nevirapine than efavirenz to achieve HIV-1 plasma viral load below 1 copy/ml. AIDS (London, England), 2011, Jan-28, Volume: 25, Issue:3 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nevirapine; Retrospective Studies; Viral Load; Viremia	2011
Adherence to HIV therapeutic drug monitoring guidelines in The Netherlands. Therapeutic drug monitoring, 2011, Volume: 33, Issue:1 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Female; Guideline Adherence; HIV Infections; Humans; Lopinavir; Netherlands; Nevirapine; Pregnancy; Pyrimidinones; Randomized Controlled Trials as Topic	2011
Lack of effect from a previous single dose of nevirapine on virologic and immunologic responses after 6 months of antiretroviral regimens containing either efavirenz or lopinavir-ritonavir. Pharmacotherapy, 2011, Volume: 31, Issue:2 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Clinical Trials, Phase II as Topic; Cyclopropanes; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lopinavir; Nevirapine; Pyrimidinones; Randomized Controlled Trials as Topic; Retrospective Studies; Ritonavir; RNA, Viral; South Africa; Young Adult	2011
Impact of the N348I mutation in HIV-1 reverse transcriptase on nonnucleoside reverse transcriptase inhibitor resistance in non-subtype B HIV-1. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:4 Topics: Alkynes; Amino Acid Substitution; Benzoxazines; Cell Line; Cyclopropanes; Drug Resistance, Viral; HEK293 Cells; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Sequence Data; Mutation; Nevirapine; Nitriles; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors	2011
Human immunodeficiency virus type 1 resistance or cross-resistance to nonnucleoside reverse transcriptase inhibitors currently under development as microbicides. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:4 Topics: Alkynes; Anilides; Anti-Infective Agents; Benzoxazines; Cell Line; Cells, Cultured; Cyclopropanes; Delavirdine; Drug Resistance, Viral; Furans; Genotype; HIV-1; Humans; Nevirapine; Reverse Transcriptase Inhibitors; Thiazoles; Thioamides; Thiourea	2011
Efavirenz-based combination antiretroviral therapy after peripartum single-dose nevirapine. International journal of STD & AIDS, 2011, Volume: 22, Issue:1 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Middle Aged; Nevirapine; Peripartum Period; Pregnancy; Pregnancy Complications, Infectious; Retrospective Studies; Treatment Outcome; Viral Load	2011
Non-nucleoside reverse transcriptase inhibitors efavirenz and nevirapine inhibit cytochrome C oxidase in mouse brain regions. Neurochemical research, 2011, Volume: 36, Issue:6 Topics: Alkynes; Animals; Benzoxazines; Brain; Cyclopropanes; Electron Transport Complex IV; Male; Mice; Nevirapine; Reverse Transcriptase Inhibitors	2011
Cardiovascular risk factors in patients on long-term treatment with nevirapine- or efavirenz-based regimens. The Journal of antimicrobial chemotherapy, 2011, Volume: 66, Issue:4 Topics: Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; Blood Chemical Analysis; Blood Glucose; Cardiovascular Diseases; Carotid Arteries; Cyclopropanes; Female; Humans; Lipids; Male; Middle Aged; Nevirapine; Retrospective Studies; Risk Assessment; Ultrasonography, Doppler, Color	2011
Do nevirapine and efavirenz affect vitamin D homeostasis similarly? AIDS (London, England), 2011, Mar-27, Volume: 25, Issue:6 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; HIV Infections; Humans; Nevirapine; Vitamin D	2011
Serum Nevirapine and Efavirenz concentrations and effect of concomitant rifampicin in HIV infected children on antiretroviral therapy. Indian pediatrics, 2011, Volume: 48, Issue:12 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Child; Child, Preschool; Cross-Sectional Studies; Cyclopropanes; Drug Interactions; Drug Monitoring; Female; HIV Infections; Humans; Male; Nevirapine; Rifampin	2011
Targeted maximum likelihood estimation of effect modification parameters in survival analysis. The international journal of biostatistics, 2011, Mar-30, Volume: 7, Issue:1 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Clinical Trials as Topic; Cyclopropanes; Female; HIV Infections; Humans; Likelihood Functions; Male; Nevirapine; Proportional Hazards Models; Sex Factors; Survival Analysis	2011
Effects of nevirapine and efavirenz on human adipocyte differentiation, gene expression, and release of adipokines and cytokines. Antiviral research, 2011, Volume: 91, Issue:2 Topics: Adipocytes; Adipogenesis; Adipokines; Alkynes; Anti-Retroviral Agents; Benzoxazines; CCAAT-Enhancer-Binding Protein-alpha; Cell Survival; Cells, Cultured; Cyclopropanes; Cytokines; Down-Regulation; Gene Expression; Hepatocyte Growth Factor; Humans; Lactic Acid; Microbial Sensitivity Tests; Nevirapine; Plasminogen Activator Inhibitor 1; PPAR gamma; RNA-Directed DNA Polymerase; Sterol Regulatory Element Binding Protein 1	2011
[Comparative study of two anti-antiretroviral protocols used for treatment of a cohort of HIV 1-positive patients followed at the Institute of Public Health and Hygiene in Dakar, Senegal]. Medecine tropicale : revue du Corps de sante colonial, 2011, Volume: 71, Issue:2 Topics: Academies and Institutes; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; HIV Seropositivity; HIV-1; Humans; Hygiene; Lamivudine; Nevirapine; Public Health; Quality of Life; Retrospective Studies; Senegal; Survival Analysis; Treatment Outcome; Zidovudine	2011
Usefulness of methadone plasma concentration measurement in patients receiving nevirapine or efavirenz. The American journal of drug and alcohol abuse, 2011, Volume: 37, Issue:4 Topics: Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Dose-Response Relationship, Drug; Drug Interactions; Humans; Methadone; Nevirapine; Reverse Transcriptase Inhibitors; Substance Withdrawal Syndrome	2011
Rilpivirine: a step forward in tailored HIV treatment. Lancet (London, England), 2011, Jul-16, Volume: 378, Issue:9787 Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Clinical Trials, Phase III as Topic; Cyclopropanes; Delavirdine; Deoxycytidine; Drug Design; Drug Resistance, Viral; Emtricitabine; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Multicenter Studies as Topic; Mutation; Nevirapine; Nitriles; Organophosphonates; Pyrimidines; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Rilpivirine; Tenofovir; Viral Load	2011
Nonnucleoside reverse transcriptase inhibitor-resistant HIV is stimulated by efavirenz during early stages of infection. Journal of virology, 2011, Volume: 85, Issue:20 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Mutation, Missense; Nevirapine; Nitriles; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; Virus Replication	2011
Antiretroviral resistance patterns and factors associated with resistance in adult patients failing NNRTI-based regimens in the Western Cape, South Africa. Journal of medical virology, 2011, Volume: 83, Issue:10 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cross-Sectional Studies; Cyclopropanes; Drug Resistance, Viral; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Male; Nevirapine; Nitriles; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; RNA, Viral; South Africa; Treatment Failure; Viral Load; Zidovudine	2011
A376S in the connection subdomain of HIV-1 reverse transcriptase confers increased risk of virological failure to nevirapine therapy. The Journal of infectious diseases, 2011, Sep-01, Volume: 204, Issue:5 Topics: Adult; Alkynes; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; Female; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Male; Middle Aged; Models, Molecular; Mutation; Nevirapine; Protein Structure, Tertiary; Reverse Transcriptase Inhibitors; Risk Factors; Treatment Failure; Viral Load	2011
The rate of accumulation of nonnucleoside reverse transcriptase inhibitor (NNRTI) resistance in patients kept on a virologically failing regimen containing an NNRTI. HIV medicine, 2012, Volume: 13, Issue:1* Topics: Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; DNA Mutational Analysis; Drug Resistance, Viral; Female; HIV Infections; Humans; Male; Middle Aged; Mutation; Nevirapine; Prospective Studies; Reverse Transcriptase Inhibitors; Viral Load; Young Adult	2012
Prevalence of etravirine-associated mutations in clinical samples with genotypic resistance to nevirapine and efavirenz in Brazilian clinics. Journal of acquired immune deficiency syndromes (1999), 2011, Volume: 57 Suppl 3 Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Brazil; Cyclopropanes; Drug Resistance, Viral; HIV; HIV Infections; Humans; Mutation, Missense; Nevirapine; Nitriles; Prevalence; Pyridazines; Pyrimidines	2011
In vitro activity of antiretroviral drugs against Plasmodium falciparum. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:11 Topics: Alkynes; Animals; Anti-Retroviral Agents; Antimalarials; Benzoxazines; Carbamates; Cyclopropanes; Darunavir; Furans; Lopinavir; Nelfinavir; Nevirapine; Plasmodium falciparum; Pyridines; Pyrones; Ritonavir; Saquinavir; Sulfonamides	2011
Docking analysis and resistance evaluation of clinically relevant mutations associated with the HIV-1 non-nucleoside reverse transcriptase inhibitors nevirapine, efavirenz and etravirine. ChemMedChem, 2011, Dec-09, Volume: 6, Issue:12 Topics: Alkynes; Amino Acid Substitution; Benzoxazines; Binding Sites; Computer Simulation; Cyclopropanes; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Hydrogen Bonding; Nevirapine; Nitriles; Protein Structure, Tertiary; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors	2011
HAART induced adverse drug reactions: a retrospective analysis at a tertiary referral health care center in India. The International journal of risk & safety in medicine, 2011, Volume: 23, Issue:3 Topics: Alkynes; Anemia; Antiretroviral Therapy, Highly Active; Benzoxazines; Chemical and Drug Induced Liver Injury; Cyclopropanes; Exanthema; Female; Gastritis; HIV Infections; Humans; India; Lamivudine; Male; Nevirapine; Peripheral Nervous System Diseases; Pharmacovigilance; Retrospective Studies; Severity of Illness Index; Sjogren's Syndrome; Stavudine	2011
Multiple drugs and multiple targets: an analysis of the electrostatic determinants of binding between non-nucleoside HIV-1 reverse transcriptase inhibitors and variants of HIV-1 RT. Proteins, 2012, Volume: 80, Issue:2 Topics: Alkynes; Benzoxazines; Binding Sites; Cyclopropanes; HIV Reverse Transcriptase; Mutation; Nevirapine; Nitriles; Protein Conformation; Pyrimidines; Reverse Transcriptase Inhibitors; Rilpivirine; Static Electricity	2012
Reasons for and correlates of antiretroviral treatment interruptions in a cohort of patients from public and private clinics in southern India. AIDS care, 2012, Volume: 24, Issue:6 Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cohort Studies; Cyclopropanes; Delivery of Health Care; Female; HIV Seropositivity; HIV-1; Humans; India; Male; Medication Adherence; Nevirapine; Private Sector; Prospective Studies; Public Sector; Surveys and Questionnaires; Treatment Outcome; Viral Load	2012
Resistance patterns selected by nevirapine vs. efavirenz in HIV-infected patients failing first-line antiretroviral treatment: a bayesian analysis. PloS one, 2011, Volume: 6, Issue:11 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Bayes Theorem; Benzoxazines; Cluster Analysis; Cyclopropanes; Demography; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Male; Models, Genetic; Molecular Sequence Data; Mutation; Nevirapine; Odds Ratio; Reverse Transcriptase Inhibitors; Treatment Failure	2011
Costs and benefits of multidrug, multidose antiretroviral therapy for prevention of mother-to-child transmission of HIV in the Dominican Republic. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2012, Volume: 116, Issue:3 Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cost-Benefit Analysis; Cyclopropanes; Dominican Republic; Drug Administration Schedule; Drug Costs; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Zidovudine	2012
Treatment challenges in co-infected HIV and TB children. Indian pediatrics, 2011, Volume: 48, Issue:12 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Female; HIV Infections; Humans; Male; Nevirapine; Rifampin	2011
Emerging mutations and associated factors in patients displaying treatment failure on an etravirine-containing regimen. Antiviral therapy, 2012, Volume: 17, Issue:1 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Male; Molecular Typing; Mutation; Nevirapine; Nitriles; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Failure; Viral Load	2012
Use of dried blood spots for the determination of plasma concentrations of nevirapine and efavirenz. The Journal of antimicrobial chemotherapy, 2012, Volume: 67, Issue:5 Topics: Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; Blood Chemical Analysis; Cyclopropanes; Desiccation; Drug Monitoring; Female; HIV Infections; Humans; Male; Middle Aged; Nevirapine; Plasma; Specimen Handling	2012
Associations between ABCB1, CYP2A6, CYP2B6, CYP2D6, and CYP3A5 alleles in relation to efavirenz and nevirapine pharmacokinetics in HIV-infected individuals. Therapeutic drug monitoring, 2012, Volume: 34, Issue:2 Topics: Adult; Alkynes; Alleles; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzoxazines; Chromatography, High Pressure Liquid; Cyclopropanes; Drug Monitoring; Female; Genotype; Haplotypes; HIV Infections; Humans; Male; Middle Aged; Nevirapine; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide	2012
Adverse drug reactions to antiretroviral therapy (ARVs): incidence, type and risk factors in Nigeria. BMC clinical pharmacology, 2012, Feb-27, Volume: 12 Topics: Adenine; Adolescent; Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Cohort Studies; Cyclopropanes; Drug-Related Side Effects and Adverse Reactions; Exanthema; Female; HIV Infections; Humans; Incidence; Lamivudine; Male; Middle Aged; Nevirapine; Nigeria; Organophosphonates; Pain; Retrospective Studies; Risk Factors; Stavudine; Tenofovir; Zidovudine	2012
Projecting the clinical benefits and risks of using efavirenz-containing antiretroviral therapy regimens in women of childbearing age. AIDS (London, England), 2012, Mar-13, Volume: 26, Issue:5 Topics: Abnormalities, Drug-Induced; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Computer Simulation; Cote d'Ivoire; Cyclopropanes; Female; HIV Infections; Humans; Nevirapine; Prognosis; Risk Assessment; Survival Rate	2012
Safety and effectiveness of efavirenz versus nevirapine-based regimens in resource-limited settings: evidence, clinical practice and modelling projections. AIDS (London, England), 2012, Mar-13, Volume: 26, Issue:5 Topics: Abnormalities, Drug-Induced; Alkynes; Anti-HIV Agents; Benzoxazines; Computer Simulation; Cyclopropanes; Female; HIV Infections; Humans; Nevirapine	2012
Susceptibility to etravirine of HIV type 1 subtype C isolates from nevirapine/efavirenz-experienced patients: comparative interpretation of ANRS and STANFORD algorithms. AIDS research and human retroviruses, 2012, Volume: 28, Issue:12 Topics: Alkynes; Amino Acid Sequence; Anti-HIV Agents; Benzoxazines; Cyclopropanes; DNA, Viral; Drug Resistance, Viral; HIV Infections; HIV Integrase; HIV-1; Humans; Molecular Sequence Data; Mozambique; Nevirapine; Nitriles; Proviruses; Pyridazines; Pyrimidines; Sequence Analysis, DNA	2012
The effect of efavirenz versus nevirapine-containing regimens on immunologic, virologic and clinical outcomes in a prospective observational study. AIDS (London, England), 2012, Aug-24, Volume: 26, Issue:13 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Administration Schedule; Female; Follow-Up Studies; HIV Reverse Transcriptase; HIV Seropositivity; HIV-1; Humans; Male; Nevirapine; Prospective Studies; Reverse Transcriptase Inhibitors; Treatment Outcome; Viral Load	2012
Panel of prototypical recombinant infectious molecular clones resistant to nevirapine, efavirenz, etravirine, and rilpivirine. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:8 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cloning, Molecular; Cyclopropanes; Drug Resistance, Multiple, Viral; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Nevirapine; Nitriles; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; Rilpivirine	2012
Nevirapine- and efavirenz-associated hepatotoxicity under programmatic conditions in Kenya and Mozambique. International journal of STD & AIDS, 2012, Volume: 23, Issue:6 Topics: Adult; Alkynes; Analysis of Variance; Anti-HIV Agents; Benzoxazines; Chemical and Drug Induced Liver Injury; Clinical Protocols; Cyclopropanes; Female; HIV Infections; Humans; Kaplan-Meier Estimate; Kenya; Male; Mozambique; Nevirapine; Odds Ratio; Retrospective Studies; Risk Factors	2012
Connection domain mutations during antiretroviral treatment failure in Mali: frequencies and impact on reverse transcriptase inhibitor activity. Journal of acquired immune deficiency syndromes (1999), 2012, Nov-01, Volume: 61, Issue:3 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Binding Sites; Cyclopropanes; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Mali; Mutation; Nevirapine; Phenotype; Treatment Failure	2012
Underlying genetic structure impacts the association between CYP2B6 polymorphisms and response to efavirenz and nevirapine. AIDS (London, England), 2012, Oct-23, Volume: 26, Issue:16 Topics: Acquired Immunodeficiency Syndrome; Alkynes; Anti-HIV Agents; Aryl Hydrocarbon Hydroxylases; Benzoxazines; Cyclopropanes; Cytochrome P-450 CYP2B6; Female; Genetic Variation; Genotype; Humans; Nevirapine; Oxidoreductases, N-Demethylating; Polymorphism, Single Nucleotide; United States; Viral Load	2012
Effect of efavirenz versus nevirapine in antiretroviral-naive individuals in the HIV-CAUSAL Collaboration Cohort. AIDS (London, England), 2012, Oct-23, Volume: 26, Issue:16 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Coinfection; Cyclopropanes; Dose-Response Relationship, Drug; Drug Administration Schedule; Hepatitis C; HIV Infections; Humans; Nevirapine; Reverse Transcriptase Inhibitors	2012
In vitro and ex vivo inhibition of human telomerase by anti-HIV nucleoside reverse transcriptase inhibitors (NRTIs) but not by non-NRTIs. PloS one, 2012, Volume: 7, Issue:11 Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Cell Line; Cyclopropanes; Didanosine; Dideoxynucleosides; DNA Primers; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Telomerase; Tenofovir; Zidovudine	2012
The advantages of therapeutic drug monitoring in patients receiving antiretroviral treatment and experiencing medication-related problems. Therapeutic drug monitoring, 2013, Volume: 35, Issue:1 Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Cohort Studies; Cyclopropanes; Drug Monitoring; HIV Infections; HIV Protease Inhibitors; Humans; Lopinavir; Nevirapine; Oligopeptides; Prospective Studies; Pyridines; Reverse Transcriptase Inhibitors	2013
Impact of hepatitis C virus on HIV response to antiretroviral therapy in Nigeria. Journal of acquired immune deficiency syndromes (1999), 2013, Feb-01, Volume: 62, Issue:2 Topics: Adult; Alanine Transaminase; Alkynes; Anti-Retroviral Agents; Benzoxazines; Chemical and Drug Induced Liver Injury; Coinfection; Cyclopropanes; Deoxycytidine; Drug Combinations; Drug Therapy, Combination; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Female; Hepacivirus; Hepatitis C, Chronic; HIV Infections; Humans; Lamivudine; Logistic Models; Male; Nevirapine; Nigeria; Organophosphorus Compounds; RNA, Viral; Stavudine; Zidovudine	2013
Impact of minority nonnucleoside reverse transcriptase inhibitor resistance mutations on resistance genotype after virologic failure. The Journal of infectious diseases, 2013, Mar-15, Volume: 207, Issue:6 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; Female; Gene Dosage; Genotype; HIV Infections; HIV-1; Humans; Male; Multivariate Analysis; Mutation; Nevirapine; Reverse Transcriptase Inhibitors; Treatment Failure	2013
A fast and reliable reversed phase high performance liquid chromatography method for simultaneous determination of selected anti-retroviral and lumefantrine in human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013, Mar-01, Volume: 919-920 Topics: Alkynes; Anti-Retroviral Agents; Antimalarials; Benzoxazines; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Cyclopropanes; Drug Stability; Ethanolamines; Fluorenes; Humans; Least-Squares Analysis; Lumefantrine; Nevirapine; Reproducibility of Results	2013
Risk of tuberculosis after antiretroviral treatment initiation: a comparison between efavirenz and nevirapine using inverse probability weighting. Antiviral therapy, 2013, Volume: 18, Issue:4 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cohort Studies; Comorbidity; Cyclopropanes; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Mycobacterium tuberculosis; Nevirapine; Proportional Hazards Models; Risk Factors; Survival Analysis; Tuberculosis, Pulmonary; Uganda; Viral Load	2013
ART and tuberculosis: the final nail in nevirapine's coffin? The Lancet. Infectious diseases, 2013, Volume: 13, Issue:4 Topics: Alkynes; Anti-HIV Agents; Antitubercular Agents; Benzoxazines; Cyclopropanes; Female; HIV Infections; Humans; Male; Nevirapine; Tuberculosis	2013
[Tenofovir hypersensitivity to tenofovir (DRESS) syndrome in a female patient infected by HIV]. Medecine et maladies infectieuses, 2013, Volume: 43, Issue:3 Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Asthenia; Benzoxazines; Cyclopropanes; Deoxycytidine; Dideoxynucleosides; Drug Eruptions; Drug Hypersensitivity; Drug Substitution; Emtricitabine; Female; Fever; HIV Infections; Humans; Lamivudine; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; Syndrome; Tenofovir	2013
HIV-1 drug resistance among newly HIV-1 infected individuals attending tertiary referral center in Chennai, India. Indian journal of medical sciences, 2011, Volume: 65, Issue:11 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Delavirdine; Drug Resistance, Viral; Genotype; HIV Infections; HIV-1; Humans; India; Nevirapine; Polymorphism, Genetic; Reverse Transcriptase Inhibitors; Tertiary Care Centers	2011
Cardiometabolic risk factors among HIV patients on antiretroviral therapy. Lipids in health and disease, 2013, Apr-10, Volume: 12 Topics: Adenine; Adolescent; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Cyclopropanes; Female; HIV; HIV Infections; Humans; Insulin Resistance; Lamivudine; Male; Middle Aged; Nevirapine; Organophosphonates; Risk Factors; Stavudine; Tenofovir; Triglycerides; Zambia; Zidovudine	2013
Association between efavirenz-based compared with nevirapine-based antiretroviral regimens and virological failure in HIV-infected children. JAMA, 2013, May-01, Volume: 309, Issue:17 Topics: Adolescent; Alkynes; Anti-Retroviral Agents; Benzoxazines; Botswana; Child; Child, Preschool; Cohort Studies; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Nevirapine; Regression Analysis; Retrospective Studies; RNA, Viral; Treatment Failure; Viral Load	2013
Left ventricular hypertrophy detected by echocardiography in HIV-infected patients. European journal of internal medicine, 2013, Volume: 24, Issue:6 Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Carbamates; Comorbidity; Cross-Sectional Studies; Cyclopropanes; Diabetes Mellitus; Drug Combinations; Dyslipidemias; Echocardiography; Female; Furans; HIV Infections; Humans; Hypertension; Hypertrophy, Left Ventricular; Lamivudine; Lopinavir; Male; Middle Aged; Nevirapine; Organophosphates; Organophosphonates; Risk Factors; Ritonavir; Smoking; Spain; Sulfonamides; Tenofovir; Zidovudine	2013
Nucleoside reverse transcriptase inhibitor resistance mutations associated with first-line stavudine-containing antiretroviral therapy: programmatic implications for countries phasing out stavudine. The Journal of infectious diseases, 2013, Jun-15, Volume: 207 Suppl 2 Topics: Adenine; Alkynes; Anti-Retroviral Agents; Benzoxazines; Cyclopropanes; Databases, Factual; Drug Resistance, Viral; Drug Therapy, Combination; Genotype; HIV Infections; HIV-1; Humans; Mutation, Missense; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Tenofovir; Zidovudine	2013
Durability of first ART regimen and risk factors for modification, interruption or death in HIV-positive patients starting ART in Europe and North America 2002-2009. AIDS (London, England), 2013, Mar-13, Volume: 27, Issue:5 Topics: Adenine; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cohort Studies; Cyclopropanes; Deoxycytidine; Dideoxynucleosides; Drug Combinations; Emtricitabine; Europe; HIV Infections; HIV Protease Inhibitors; HIV Seropositivity; HIV-1; Humans; Lamivudine; Lopinavir; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; Risk Factors; Tenofovir; Time Factors; United States	2013
Economic evaluation of 3-drug antiretroviral regimens for the prevention of mother-to-child HIV transmission in Thailand. Asia-Pacific journal of public health, 2015, Volume: 27, Issue:2 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cost-Benefit Analysis; Cyclopropanes; Drug Therapy, Combination; Female; Health Services; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Models, Econometric; Mothers; Nevirapine; Pregnancy; Thailand; Zidovudine	2015
Factors affecting antiretroviral pharmacokinetics in HIV-infected women with virologic suppression on combination antiretroviral therapy: a cross-sectional study. BMC infectious diseases, 2013, Jun-03, Volume: 13 Topics: Adult; Alkynes; Anti-Retroviral Agents; Atazanavir Sulfate; Benzoxazines; Cross-Sectional Studies; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; Humans; Linear Models; Middle Aged; Nevirapine; Oligopeptides; Pyridines; Risk Factors; Viral Load	2013
Low risk of liver toxicity using the most recently approved antiretroviral agents but still increased in HIV-hepatitis C virus coinfected patients. AIDS (London, England), 2013, Apr-24, Volume: 27, Issue:7 Topics: Alkynes; Anti-HIV Agents; Atazanavir Sulfate; Benzoxazines; CD4 Lymphocyte Count; Chemical and Drug Induced Liver Injury; Coinfection; Cyclopropanes; Darunavir; Female; Follow-Up Studies; Hepatitis C; HIV Infections; Humans; Liver; Male; Nevirapine; Oligopeptides; Pyridines; Pyrrolidinones; Raltegravir Potassium; Ritonavir; Sulfonamides	2013
Stevens-Johnson syndrome and HIV in children in Swaziland. The Pediatric infectious disease journal, 2013, Volume: 32, Issue:12 Topics: Adolescent; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Child; Child, Preschool; Cyclopropanes; Eswatini; Female; HIV Infections; Hospitalization; Humans; Infant; Male; Nevirapine; Retrospective Studies; Stevens-Johnson Syndrome; Trimethoprim, Sulfamethoxazole Drug Combination; Young Adult	2013
Temporal association between incident tuberculosis and poor virological outcomes in a South African antiretroviral treatment service. Journal of acquired immune deficiency syndromes (1999), 2013, Nov-01, Volume: 64, Issue:3 Topics: Adult; AIDS-Related Opportunistic Infections; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cyclopropanes; Disease Progression; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; Humans; Incidence; Lamivudine; Male; Medication Adherence; Nevirapine; Risk Factors; South Africa; Stavudine; Time Factors; Tuberculosis; Viral Load	2013
Comparative durability of nevirapine versus efavirenz in first-line regimens during the first year of initiating antiretroviral therapy among Swaziland HIV-infected adults. The Pan African medical journal, 2013, Volume: 15 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cohort Studies; Cyclopropanes; Eswatini; Female; Follow-Up Studies; HIV Infections; Humans; Incidence; Male; Multivariate Analysis; Nevirapine; Proportional Hazards Models; Retrospective Studies; Reverse Transcriptase Inhibitors; Treatment Outcome; Tuberculosis	2013
Evaluation of residual viremia and quantitation of soluble CD14 in a large cohort of HIV-infected adults on a long-term non-nucleoside reverse transcriptase inhibitor-based regimen. Journal of medical virology, 2013, Volume: 85, Issue:11 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cohort Studies; Cross-Sectional Studies; Cyclopropanes; Enzyme-Linked Immunosorbent Assay; Female; HIV Infections; HIV-1; Humans; Lipopolysaccharide Receptors; Male; Middle Aged; Monocytes; Nevirapine; Reverse Transcriptase Inhibitors; Viral Load; Viremia	2013
Sensitive assessment of the virologic outcomes of stopping and restarting non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy. PloS one, 2013, Volume: 8, Issue:7 Topics: Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Chromatography, High Pressure Liquid; Cyclopropanes; DNA Mutational Analysis; Drug Resistance, Viral; Female; High-Throughput Nucleotide Sequencing; HIV Infections; HIV-1; Humans; Logistic Models; Male; Middle Aged; Nevirapine; Odds Ratio; Reverse Transcriptase Inhibitors	2013
HIV-1 drug-resistance surveillance among treatment-experienced and -naïve patients after the implementation of antiretroviral therapy in Ghana. PloS one, 2013, Volume: 8, Issue:8 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Child; Child, Preschool; Cyclopropanes; Drug Resistance, Viral; Epidemiological Monitoring; Female; Ghana; HIV Infections; HIV Protease; HIV-1; Humans; Infant; Lamivudine; Male; Middle Aged; Molecular Epidemiology; Molecular Typing; Mutation, Missense; Nevirapine; Prevalence; Sequence Analysis, DNA; Stavudine; Zidovudine	2013
High-levels of acquired drug resistance in adult patients failing first-line antiretroviral therapy in a rural HIV treatment programme in KwaZulu-Natal, South Africa. PloS one, 2013, Volume: 8, Issue:8 Topics: Adolescent; Adult; Alkynes; Analysis of Variance; Anti-HIV Agents; Benzoxazines; Cross-Sectional Studies; Cyclopropanes; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Mutation; Nevirapine; Outcome Assessment, Health Care; Prevalence; South Africa; Stavudine; Young Adult; Zidovudine	2013
Role of the K101E substitution in HIV-1 reverse transcriptase in resistance to rilpivirine and other nonnucleoside reverse transcriptase inhibitors. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:11 Topics: Alkynes; Amino Acid Substitution; Benzoxazines; Cyclopropanes; Delavirdine; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; HEK293 Cells; HIV Reverse Transcriptase; HIV-1; Humans; Leukocytes, Mononuclear; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Nevirapine; Nitriles; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; Rilpivirine; Virus Replication	2013
Long-term effectiveness of first-line non-nucleoside reverse transcriptase inhibitor (NNRTI)-based antiretroviral therapy in Ghana. The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:1 Topics: Adult; Alkynes; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Female; Ghana; HIV Infections; Humans; Male; Middle Aged; Nevirapine; Retrospective Studies; Reverse Transcriptase Inhibitors; Survival Analysis; Treatment Outcome; Viral Load; Withholding Treatment	2014
A novel, cell-free PCR-based assay for evaluating the inhibitory activity of antiretroviral compounds against HIV reverse transcriptase. Journal of medical virology, 2014, Volume: 86, Issue:1 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; DNA, Complementary; Drug Evaluation, Preclinical; HIV Reverse Transcriptase; Humans; Microbial Sensitivity Tests; Nevirapine; Polymerase Chain Reaction; Reproducibility of Results; Reverse Transcriptase Inhibitors; Reverse Transcription; Sensitivity and Specificity	2014
Efavirenz induces interactions between leucocytes and endothelium through the activation of Mac-1 and gp150,95. The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:4 Topics: Alkynes; Animals; Anti-HIV Agents; Benzoxazines; Cell Adhesion; Cells, Cultured; Cyclopropanes; Endothelium; Flow Cytometry; Gene Expression Profiling; Humans; Integrin alphaXbeta2; Leukocytes; Lopinavir; Macrophage-1 Antigen; Male; Nevirapine; Rats; Rats, Sprague-Dawley	2014
Implementing the Jadelle implant for women living with HIV in a resource-limited setting: concerns for drug interactions leading to unintended pregnancies. AIDS (London, England), 2014, Mar-13, Volume: 28, Issue:5 Topics: Adolescent; Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Contraceptive Agents, Female; Cyclopropanes; Drug Interactions; Eswatini; Female; HIV Infections; Humans; Lopinavir; Middle Aged; Nevirapine; Pregnancy; Pregnancy, Unplanned; Ritonavir; Young Adult	2014
Effect of antiretroviral drugs on the DNA damage in mice. Environmental toxicology and pharmacology, 2014, Volume: 37, Issue:1 Topics: Alkynes; Animals; Anti-HIV Agents; Benzoxazines; Bone Marrow Cells; Brain; Comet Assay; Cyclopropanes; DNA Damage; Erythrocytes; Liver; Male; Mice; Micronucleus Tests; Myocardium; Nevirapine; Reverse Transcriptase Inhibitors	2014
Lack of association between plasma levels of non-nucleoside reverse transcriptase inhibitors & virological outcomes during rifampicin co-administration in HIV-infected TB patients. The Indian journal of medical research, 2013, Volume: 138, Issue:6 Topics: Adult; Alkynes; Benzoxazines; Cyclopropanes; Cytochrome P-450 CYP2B6; Female; Genetic Association Studies; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; Rifampin; Tuberculosis	2013
Hepatitis B and C co-infection among HIV-infected adults while on antiretroviral treatment: long-term survival, CD4 cell count recovery and antiretroviral toxicity in Cambodia. PloS one, 2014, Volume: 9, Issue:2 Topics: Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Cambodia; CD4 Lymphocyte Count; Coinfection; Cyclopropanes; Female; Hepatitis B; Hepatitis C; HIV Infections; Humans; Kaplan-Meier Estimate; Lamivudine; Liver; Logistic Models; Male; Middle Aged; Nevirapine; Proportional Hazards Models; Retrospective Studies; Stavudine; Treatment Outcome; Zidovudine	2014
Significant decrease of ethinylestradiol with nevirapine, and of etonogestrel with efavirenz in HIV-positive women. Journal of acquired immune deficiency syndromes (1999), 2014, Jun-01, Volume: 66, Issue:2 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Contraceptive Agents, Female; Cyclopropanes; Desogestrel; Dose-Response Relationship, Drug; Drug Interactions; Ethinyl Estradiol; Female; HIV Infections; Humans; Nevirapine; Prospective Studies	2014
Challenges of antiretroviral treatment monitoring in rural and remote-access regions in Africa. AIDS research and human retroviruses, 2014, Volume: 30, Issue:7 Topics: Acquired Immunodeficiency Syndrome; Adult; Africa; Alkynes; Anti-HIV Agents; Benzoxazines; Cross-Sectional Studies; Cyclopropanes; Drug Monitoring; Drug Resistance, Viral; Female; HIV-1; Hospitals, Rural; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Rural Health Services; Rural Population; Stavudine; Treatment Outcome; Zidovudine	2014
Uptake of prevention of mother-to-child-transmission using Option B+ in northern rural Malawi: a retrospective cohort study. Sexually transmitted infections, 2014, Volume: 90, Issue:4 Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Chemoprevention; Cohort Studies; Cyclopropanes; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Malawi; Nevirapine; Organophosphonates; Pregnancy; Pregnancy Complications, Infectious; Prenatal Care; Retrospective Studies; Rural Population; Tenofovir; Young Adult	2014
Presence of HIV drug resistance in antiretroviral therapy-naive and -experienced patients from Papua New Guinea. The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:8 Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Dried Blood Spot Testing; Drug Resistance, Viral; Female; HIV Infections; HIV Seropositivity; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Papua New Guinea; Reverse Transcriptase Inhibitors; Stavudine; Treatment Failure; Viral Load; Young Adult; Zidovudine	2014
Incidence and determinants of nevirapine and efavirenz-related skin rashes in West Africans: nevirapine's epitaph? PloS one, 2014, Volume: 9, Issue:4 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Exanthema; Female; Ghana; Humans; Incidence; Male; Middle Aged; Nevirapine; Retrospective Studies; Risk Factors; Severity of Illness Index	2014
MicroRNA-150 is a potential biomarker of HIV/AIDS disease progression and therapy. PloS one, 2014, Volume: 9, Issue:5 Topics: Acquired Immunodeficiency Syndrome; Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Biomarkers; CD4 Lymphocyte Count; Cyclopropanes; Disease Progression; Drug Resistance, Viral; Female; Gene Expression Regulation; HIV; Humans; Lamivudine; Leukocytes, Mononuclear; Male; MicroRNAs; Nevirapine; Stavudine; Treatment Outcome; Viral Load; Zidovudine	2014
Effects of the W153L substitution in HIV reverse transcriptase on viral replication and drug resistance to multiple categories of reverse transcriptase inhibitors. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:8 Topics: Adenine; Alkynes; Amino Acid Substitution; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; HEK293 Cells; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Mutation; Nevirapine; Organophosphonates; Pyrimidines; Recombinant Proteins; Reverse Transcriptase Inhibitors; Tenofovir; Virus Replication	2014
Impact of Y181C and/or H221Y mutation patterns of HIV-1 reverse transcriptase on phenotypic resistance to available non-nucleoside and nucleoside inhibitors in China. BMC infectious diseases, 2014, May-05, Volume: 14 Topics: Alkynes; Benzoxazines; China; Cyclopropanes; Drug Resistance, Multiple, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Nevirapine; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine	2014
Outcome of artemether-lumefantrine treatment for uncomplicated malaria in HIV-infected adult patients on anti-retroviral therapy. Malaria journal, 2014, May-30, Volume: 13 Topics: Adult; Africa South of the Sahara; Aged; Alkynes; Anti-Retroviral Agents; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Benzoxazines; Cyclopropanes; Drug Combinations; Drug Interactions; Ethanolamines; Female; Fluorenes; HIV Infections; Humans; Malaria; Male; Middle Aged; Nevirapine; Prospective Studies; Treatment Outcome; Young Adult	2014
Switching from efavirenz to nevirapine in children: 1-week dose escalation strategy. AIDS research and human retroviruses, 2014, Volume: 30, Issue:8 Topics: Adolescent; Alkynes; Anti-HIV Agents; Benzoxazines; Child; Cyclopropanes; Female; HIV Infections; Humans; Male; Nevirapine; Retrospective Studies	2014
Etravirine and rilpivirine-specific mutations selected by efavirenz and nevirapine exposure in patients infected with HIV-1 non-B subtypes. AIDS (London, England), 2014, Sep-24, Volume: 28, Issue:15 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Mutation, Missense; Nevirapine; Nitriles; Pyridazines; Pyrimidines; Rilpivirine; Treatment Outcome; Viral Load	2014
Nevirapine or efavirenz for tuberculosis and HIV coinfected patients: exposure and virological failure relationship. The Journal of antimicrobial chemotherapy, 2015, Volume: 70, Issue:1 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antitubercular Agents; Benzoxazines; Cyclopropanes; Drug Tolerance; Female; HIV Infections; Humans; Male; Middle Aged; Nevirapine; Treatment Outcome; Tuberculosis	2015
Use of in vitro to in vivo extrapolation to predict the optimal strategy for patients switching from efavirenz to maraviroc or nevirapine. Clinical pharmacokinetics, 2015, Volume: 54, Issue:1 Topics: Adolescent; Adult; Aged; Alkynes; Anti-Retroviral Agents; Benzoxazines; Clinical Trials as Topic; Computer Simulation; Cyclohexanes; Cyclopropanes; Dose-Response Relationship, Drug; Female; HIV Fusion Inhibitors; Humans; In Vitro Techniques; Male; Maraviroc; Middle Aged; Models, Biological; Nevirapine; Reverse Transcriptase Inhibitors; Triazoles; Young Adult	2015
The relation between efavirenz versus nevirapine and virologic failure in Johannesburg, South Africa. Journal of the International AIDS Society, 2014, Volume: 17 Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Female; Follow-Up Studies; HIV; HIV Infections; Humans; Male; Middle Aged; Nevirapine; South Africa; Treatment Failure; Viremia; Young Adult	2014
Detecting virological failure in HIV-infected Tanzanian children. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2014, Jun-26, Volume: 104, Issue:10 Topics: Alkynes; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Child; Cross-Sectional Studies; Cyclopropanes; Drug Monitoring; Drug Resistance, Multiple, Viral; False Negative Reactions; False Positive Reactions; Female; HIV Infections; Humans; Male; Monitoring, Immunologic; Nevirapine; Predictive Value of Tests; Tanzania; Treatment Failure; Viral Load	2014
Clinically significant drug interactions among HIV-infected patients receiving antiretroviral therapy. The Southeast Asian journal of tropical medicine and public health, 2014, Volume: 45, Issue:5 Topics: Adult; Age Factors; Alkynes; Ambulatory Care Facilities; Anti-Retroviral Agents; Benzoxazines; Cross-Sectional Studies; Cyclopropanes; Drug Interactions; Female; HIV Infections; Humans; Male; Middle Aged; Nevirapine; Polypharmacy; Prevalence; Protease Inhibitors; Risk Factors; Sex Factors; Thailand	2014
In vitro selection of HIV-1 CRF08_BC variants resistant to reverse transcriptase inhibitors. AIDS research and human retroviruses, 2015, Volume: 31, Issue:2 Topics: Alkynes; Benzoxazines; Cells, Cultured; China; Cyclopropanes; Drug Resistance, Viral; Genotype; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Molecular Sequence Data; Mutant Proteins; Mutation, Missense; Nevirapine; Reverse Transcriptase Inhibitors; Selection, Genetic; Sequence Analysis, DNA; Virus Cultivation	2015
Nevirapine-related adverse events among children switched from efavirenz to nevirapine as compared to children who were started on nevirapine-based antiretroviral therapy directly. AIDS care, 2015, Volume: 27, Issue:5 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Child; Child, Preschool; Cyclopropanes; Drug Administration Schedule; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; Humans; Incidence; India; Male; Nevirapine; Retrospective Studies; Reverse Transcriptase Inhibitors; Treatment Outcome	2015
Comprehensive evaluation of caregiver-reported antiretroviral therapy adherence for HIV-infected children. AIDS and behavior, 2015, Volume: 19, Issue:4 Topics: Adolescent; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Caregivers; Child; Child, Preschool; Cohort Studies; Cyclopropanes; Female; HIV Infections; Humans; Infant; Infant, Newborn; Kenya; Logistic Models; Male; Medication Adherence; Nevirapine; Parents; Prospective Studies; Surveys and Questionnaires	2015
Predicted residual activity of rilpivirine in HIV-1 infected patients failing therapy including NNRTIs efavirenz or nevirapine. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2015, Volume: 21, Issue:6 Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; Genotype; HIV Infections; HIV-1; Humans; Mutation, Missense; Nevirapine; Rilpivirine; Treatment Failure	2015
The effect of malnutrition on the pharmacokinetics and virologic outcomes of lopinavir, efavirenz and nevirapine in food insecure HIV-infected children in Tororo, Uganda. The Pediatric infectious disease journal, 2015, Volume: 34, Issue:3 Topics: Adolescent; Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Child; Cyclopropanes; HIV Infections; Humans; Lopinavir; Malnutrition; Models, Theoretical; Nevirapine; Poverty; Randomized Controlled Trials as Topic; Treatment Failure; Treatment Outcome; Uganda; Viral Load; Young Adult	2015
CD41 T cell recovery during suppression of HIV replication: an international comparison of the immunological efficacy of antiretroviral therapy in North America, Asia and Africa. International journal of epidemiology, 2015, Volume: 44, Issue:1 Topics: Adult; Africa; Alkynes; Anti-HIV Agents; Asia; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Nevirapine; North America; RNA, Viral; Virus Replication	2015
[Analysis on HIV suppression effect after initiating antiretroviral treatment and related factors among AIDS patients in Henan province during 2008 and 2013]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 2015, Volume: 49, Issue:1 Topics: Acquired Immunodeficiency Syndrome; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Female; Health Facilities; HIV Infections; Humans; Lamivudine; Male; Nevirapine; Stavudine; Time-to-Treatment; Treatment Outcome; Zidovudine	2015
Time trends of baseline demographics and clinical characteristics of HIV infected children enrolled in care and treatment service in Dar es Salaam, Tanzania. BMC infectious diseases, 2015, Mar-26, Volume: 15 Topics: Adolescent; Age Distribution; Alkynes; Ambulatory Care Facilities; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Child; Child, Preschool; Comorbidity; Cyclopropanes; Female; HIV Infections; Humans; Infant; Lamivudine; Linear Models; Male; Nevirapine; Severity of Illness Index; Tanzania; Tuberculosis; Zidovudine	2015
The influence of nevirapine and efavirenz-based anti-retroviral therapy on the pharmacokinetics of lumefantrine and anti-malarial dose recommendation in HIV-malaria co-treatment. Malaria journal, 2015, Apr-25, Volume: 14 Topics: Adult; Aged; Alkynes; Anti-Retroviral Agents; Antimalarials; Benzoxazines; Cyclopropanes; Drug Interactions; Ethanolamines; Female; Fluorenes; HIV Infections; Humans; Lumefantrine; Malaria; Male; Middle Aged; Nevirapine; Prospective Studies; Tanzania; Young Adult	2015
Lack of evidence for the selection of E138 mutations by first-generation non-nucleoside reverse transcriptase inhibitors in patients infected with HIV-1 non-B subtypes. AIDS (London, England), 2015, May-15, Volume: 29, Issue:8 Topics: Alkynes; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Nevirapine; Reverse Transcriptase Inhibitors	2015
Current Efavirenz (EFV) or ritonavir-boosted lopinavir (LPV/r) use correlates with elevate markers of atherosclerosis in HIV-infected subjects in Addis Ababa, Ethiopia. PloS one, 2015, Volume: 10, Issue:4 Topics: Adult; Alkynes; Anti-HIV Agents; Atherosclerosis; Benzoxazines; Biomarkers; Blood Pressure; C-Reactive Protein; Carotid Intima-Media Thickness; Case-Control Studies; Cholesterol, HDL; Cholesterol, LDL; Cyclopropanes; Ethiopia; Female; Heart Rate; HIV Infections; HIV-1; Humans; Lipodystrophy; Lopinavir; Male; Middle Aged; Nevirapine; Pulse Wave Analysis; Ritonavir; Triglycerides	2015
CYP2B66 genotype and high efavirenz plasma concentration but not nevirapine are associated with low lumefantrine plasma exposure and poor treatment response in HIV-malaria-coinfected patients. The pharmacogenomics journal, 2016, Volume: 16, Issue:1* Topics: Alkynes; Anti-HIV Agents; Antimalarials; Artemether; Artemisinins; ATP Binding Cassette Transporter, Subfamily B; Benzoxazines; Case-Control Studies; Coinfection; Cyclopropanes; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Drug Antagonism; Drug Therapy, Combination; Ethanolamines; Fluorenes; Genotype; HIV Infections; Humans; Lumefantrine; Malaria; Nevirapine; Prospective Studies	2016
Quality of life in patients treated with first-line antiretroviral therapy containing nevirapine or efavirenz in Uganda: a prospective non-randomized study. BMC health services research, 2015, Jul-28, Volume: 15 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Depression; Female; HIV Infections; Humans; Interviews as Topic; Male; Mental Health; Nevirapine; Prospective Studies; Quality of Life; Reverse Transcriptase Inhibitors; Treatment Outcome; Uganda; World Health Organization	2015
Outcome of neuropsychiatric symptoms related to an antiretroviral drug following its substitution by nevirapine: the RELAX study. HIV medicine, 2015, Volume: 16, Issue:10 Topics: Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Central Nervous System Diseases; Cyclopropanes; Drug Substitution; Female; HIV Infections; Humans; Male; Medication Adherence; Mental Disorders; Middle Aged; Nevirapine; Prospective Studies; Quality of Life; Reverse Transcriptase Inhibitors	2015
CYP2B6 poor metaboliser alleles involved in efavirenz and nevirapine metabolism: CYP2B69 and CYP2B618 distribution in HIV-exposed subjects from Dschang, Western Cameroon. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 2015, Volume: 35 Topics: Adolescent; Adult; Alkynes; Benzoxazines; Black People; Cameroon; Child; Child, Preschool; Cross-Sectional Studies; Cyclopropanes; Cytochrome P-450 CYP2B6; Gene Frequency; HIV Infections; Humans; Infant; Nevirapine; Polymorphism, Single Nucleotide; Precision Medicine; Young Adult	2015
Longitudinal Analysis of Adherence to First-Line Antiretroviral Therapy: Evidence of Treatment Sustainability from an Indian HIV Cohort. Current HIV research, 2016, Volume: 14, Issue:1 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Administration Schedule; Female; HIV Infections; Humans; India; Lamivudine; Longitudinal Studies; Male; Medication Adherence; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine	2016
Inhibition of CYP2B6 by Medicinal Plant Extracts: Implication for Use of Efavirenz and Nevirapine-Based Highly Active Anti-Retroviral Therapy (HAART) in Resource-Limited Settings. Molecules (Basel, Switzerland), 2016, Feb-16, Volume: 21, Issue:2 Topics: Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2B6 Inhibitors; Herb-Drug Interactions; Humans; Magnoliopsida; Nevirapine; Plant Extracts; Plants, Medicinal	2016
Mass Spectrometric Characterization of HIV-1 Reverse Transcriptase Interactions with Non-nucleoside Reverse Transcriptase Inhibitors. Biological & pharmaceutical bulletin, 2016, Volume: 39, Issue:3 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; HIV Reverse Transcriptase; Mass Spectrometry; Nevirapine; Nitriles; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; Rilpivirine	2016
HIV-1 Antiretroviral Drug Resistance Mutations in Treatment Naïve and Experienced Panamanian Subjects: Impact on National Use of EFV-Based Schemes. PloS one, 2016, Volume: 11, Issue:4 Topics: Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; Female; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Male; Middle Aged; Mutation; Nevirapine; Panama; Prevalence; Retrospective Studies; Young Adult	2016
Role of Rilpivirine and Etravirine in Efavirenz and Nevirapine-Based Regimens Failure in a Resource-Limited Country: A Cross- Sectional Study. PloS one, 2016, Volume: 11, Issue:4 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cross-Sectional Studies; Cyclopropanes; Drug Resistance, Viral; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Male; Mutation; Nevirapine; Nitriles; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; Rilpivirine; Thailand; Viral Load; Young Adult	2016
Antileishmanial activity of antiretroviral drugs combined with miltefosine. Parasitology research, 2016, Volume: 115, Issue:10 Topics: Alkynes; Animals; Anti-Retroviral Agents; Antiprotozoal Agents; Atazanavir Sulfate; Benzoxazines; Coinfection; Cyclopropanes; Darunavir; Delavirdine; Drug Therapy, Combination; HIV Infections; Humans; Leishmania infantum; Leishmaniasis, Visceral; Macrophages; Male; Mice, Inbred BALB C; Nevirapine; Phosphorylcholine; Protease Inhibitors; Reverse Transcriptase Inhibitors; Tenofovir	2016
First-line antiretroviral therapy durability in a 10-year cohort of naïve adults started on treatment in Uganda. Journal of the International AIDS Society, 2016, Volume: 19, Issue:1 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cohort Studies; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Nevirapine; Time Factors; Treatment Failure; Uganda	2016
Adverse drug reactions associated with antiretroviral therapy in South Africa. African journal of AIDS research : AJAR, 2016, Volume: 15, Issue:3 Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dizziness; Exanthema; Female; Gynecomastia; HIV Infections; Humans; Lipodystrophy; Male; Middle Aged; Nevirapine; Peripheral Nervous System Diseases; Renal Insufficiency; Retrospective Studies; South Africa; Stavudine; Tenofovir; Zidovudine	2016
Improved Adherence to Antiretroviral Therapy Observed Among HIV-Infected Children Whose Caregivers had Positive Beliefs in Medicine in Sub-Saharan Africa. AIDS and behavior, 2017, Volume: 21, Issue:2 Topics: Africa South of the Sahara; Alkynes; Anti-HIV Agents; Attitude to Health; Benzoxazines; Caregivers; Child; Child, Preschool; Cyclopropanes; Dideoxynucleosides; Female; HIV Infections; Humans; Infant; Lamivudine; Linear Models; Logistic Models; Male; Medication Adherence; Multivariate Analysis; Nevirapine; Randomized Controlled Trials as Topic; Stavudine; Surveys and Questionnaires; Uganda; Zambia; Zidovudine	2017
Virological failure reduced with HIV-serostatus disclosure, extra baseline weight and rising CD4 cells among HIV-positive adults in Northwestern Uganda. BMC infectious diseases, 2016, Oct-28, Volume: 16, Issue:1 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Body Weight; CD4-Positive T-Lymphocytes; Cohort Studies; Cyclopropanes; Disclosure; Female; HIV Infections; HIV Seropositivity; Humans; Kaplan-Meier Estimate; Lamivudine; Male; Nevirapine; Retrospective Studies; Tenofovir; Treatment Outcome; Uganda	2016
Development of a Qualitative Quantitative Polymerase Chain Reaction Test to Identify Patients Failing First-Line Therapy to Non-Nucleotide Reverse Transcriptase Inhibitor. AIDS research and human retroviruses, 2017, Volume: 33, Issue:4 Topics: Alkynes; Benzoxazines; Costs and Cost Analysis; Cyclopropanes; Drug Monitoring; Drug Resistance, Viral; Genotyping Techniques; HIV Infections; Humans; Mutation, Missense; Nevirapine; Point Mutation; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Sensitivity and Specificity; Treatment Failure	2017
Protein expression from unintegrated HIV-1 DNA introduces bias in primary in vitro post-integration latency models. Scientific reports, 2016, 12-02, Volume: 6 Topics: Alkynes; Benzoxazines; CD4-Positive T-Lymphocytes; Cyclopropanes; DNA, Viral; Genes, Reporter; Green Fluorescent Proteins; HIV Infections; HIV Integrase Inhibitors; HIV Protease Inhibitors; HIV-1; Humans; Lymphocyte Activation; Models, Biological; Nevirapine; Primary Cell Culture; Raltegravir Potassium; Reverse Transcriptase Inhibitors; Ritonavir; Viral Proteins; Virus Integration; Virus Latency; Virus Replication	2016
Occult HIV-1 drug resistance to thymidine analogues following failure of first-line tenofovir combined with a cytosine analogue and nevirapine or efavirenz in sub Saharan Africa: a retrospective multi-centre cohort study. The Lancet. Infectious diseases, 2017, Volume: 17, Issue:3 Topics: Adult; Africa South of the Sahara; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Mutation; Nevirapine; Retrospective Studies; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Failure; Viral Load	2017
Determination of endocrine disrupting chemicals and antiretroviral compounds in surface water: A disposable sorptive sampler with comprehensive gas chromatography - Time-of-flight mass spectrometry and large volume injection with ultra-high performance li Journal of chromatography. A, 2017, May-05, Volume: 1496 Topics: Alkynes; Anti-Retroviral Agents; Benzoxazines; Chromatography, High Pressure Liquid; Cyclopropanes; Endocrine Disruptors; Gas Chromatography-Mass Spectrometry; Limit of Detection; Nevirapine; Tandem Mass Spectrometry; Water Pollutants, Chemical	2017
Virologic Response to First-line Efavirenz- or Nevirapine-based Antiretroviral Therapy in HIV-infected African Children. The Pediatric infectious disease journal, 2017, Volume: 36, Issue:6 Topics: Adolescent; Alkynes; Anti-Retroviral Agents; Benzoxazines; Child; Child, Preschool; Cyclopropanes; Female; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Male; Nevirapine; Retrospective Studies; Uganda; Viral Load; Zimbabwe	2017
Automated high throughput analysis of antiretroviral drugs in dried blood spots. Journal of mass spectrometry : JMS, 2017, Volume: 52, Issue:8 Topics: Alkynes; Anti-Retroviral Agents; Benzoxazines; Chromatography, High Pressure Liquid; Cyclopropanes; Dried Blood Spot Testing; High-Throughput Screening Assays; Humans; Limit of Detection; Lopinavir; Nevirapine; Sensitivity and Specificity; Tandem Mass Spectrometry	2017
Drug resistance testing through remote genotyping and predicted treatment options in human immunodeficiency virus type 1 infected Tanzanian subjects failing first or second line antiretroviral therapy. PloS one, 2017, Volume: 12, Issue:6 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Clinical Decision-Making; Computational Biology; Cross-Sectional Studies; Cyclopropanes; Drug Resistance, Viral; Emtricitabine; Female; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Lopinavir; Male; Monitoring, Physiologic; Nevirapine; pol Gene Products, Human Immunodeficiency Virus; Stavudine; Tanzania; Tenofovir; Treatment Failure; Viral Load	2017
Multi-state models for the analysis of time-to-treatment modification among HIV patients under highly active antiretroviral therapy in Southwest Ethiopia. BMC infectious diseases, 2017, 06-27, Volume: 17, Issue:1 Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; Ethiopia; Female; HIV Infections; Humans; Lamivudine; Male; Models, Theoretical; Nevirapine; Pregnancy; Retrospective Studies; Stavudine; Tenofovir; Time-to-Treatment; Treatment Failure; Zidovudine	2017
Efavirenz decreases etonogestrel exposure: a pharmacokinetic evaluation of implantable contraception with antiretroviral therapy. AIDS (London, England), 2017, 09-10, Volume: 31, Issue:14 Topics: Adolescent; Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Contraception; Contraceptive Agents, Female; Cyclopropanes; Desogestrel; Drug Antagonism; Female; HIV Infections; Humans; Middle Aged; Nevirapine; Uganda; Young Adult	2017
Accumulation of HIV-1 drug resistance in patients on a standard thymidine analogue-based first line antiretroviral therapy after virological failure: implications for the activity of next-line regimens from a longitudinal study in Mozambique. BMC infectious diseases, 2017, 09-05, Volume: 17, Issue:1 Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Lamivudine; Longitudinal Studies; Male; Mozambique; Mutation; Nevirapine; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Failure; Viral Load; Zidovudine	2017
Central nervous system-penetrating antiretrovirals impair energetic reserve in striatal nerve terminals. Journal of neurovirology, 2017, Volume: 23, Issue:6 Topics: Adenosine Triphosphate; Alkynes; Animals; Anti-HIV Agents; Benzoxazines; Cerebral Cortex; Corpus Striatum; Cyclohexanes; Cyclopropanes; Darunavir; Dideoxynucleosides; Dose-Response Relationship, Drug; Emtricitabine; Lopinavir; Male; Maraviroc; Mitochondria; Neurons; Nevirapine; Oxidative Phosphorylation; Permeability; Presynaptic Terminals; Raltegravir Potassium; Rats; Rats, Long-Evans; Triazoles; Zidovudine	2017
Safety Evaluation of Efavirenz in Children: Don't Forget the Central Nervous System. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2018, 03-19, Volume: 66, Issue:7 Topics: Alkynes; Benzoxazines; Child; Cyclopropanes; HIV; Humans; Lopinavir; Nervous System; Nevirapine; Ritonavir	2018
Reply to Van de Wijer et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2018, 03-19, Volume: 66, Issue:7 Topics: Alkynes; Benzoxazines; Child; Cyclopropanes; HIV; Humans; Lopinavir; Nevirapine; Ritonavir	2018
HBV, HCV, and HBV/HCV co-infection among HIV-positive patients in Hunan province, China: Regimen selection, hepatotoxicity, and antiretroviral therapy outcome. Journal of medical virology, 2018, Volume: 90, Issue:3 Topics: Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; CD4 Lymphocyte Count; Chemical and Drug Induced Liver Injury; Cohort Studies; Coinfection; Cyclopropanes; Female; Hepatitis B; Hepatitis C; HIV; HIV Infections; Humans; Male; Middle Aged; Nevirapine; Retrospective Studies; Treatment Outcome; Viral Load; Zidovudine	2018
Long-term viral suppression and immune recovery during first-line antiretroviral therapy: a study of an HIV-infected adult cohort in Hanoi, Vietnam. Journal of the International AIDS Society, 2017, Volume: 20, Issue:4 Topics: Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cohort Studies; Cyclopropanes; Female; HIV Infections; Humans; Longitudinal Studies; Male; Middle Aged; Nevirapine; Stavudine; Time Factors; Vietnam; Viral Load; Young Adult; Zidovudine	2017
A prospective study of adverse events to antiretroviral therapy in HIV- infected adults in Ekiti State, Nigeria. African journal of medicine and medical sciences, 2016, Volume: 45, Issue:2 Topics: Abdominal Pain; Adolescent; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Substitution; Drug Therapy, Combination; Female; HIV Infections; Humans; Incidence; Lamivudine; Male; Middle Aged; Nausea; Nevirapine; Nigeria; Prospective Studies; Sleep Initiation and Maintenance Disorders; Tenofovir; Young Adult; Zidovudine	2016
Antiretroviral treatment Long-Term (ALT) cohort: a prospective cohort of 10 years of ART-experienced patients in Uganda. BMJ open, 2018, 02-21, Volume: 8, Issue:2 Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Combinations; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Lamivudine; Male; Nevirapine; Prospective Studies; RNA, Viral; Time; Uganda; Viral Load; Zidovudine	2018
Prevalence of Rilpivirine and Etravirine Resistance Mutations in HIV-1 Subtype C-Infected Patients Failing Nevirapine or Efavirenz-Based Combination Antiretroviral Therapy in Botswana. AIDS research and human retroviruses, 2018, Volume: 34, Issue:8 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Botswana; Cyclopropanes; Drug Resistance, Viral; Female; Genotype; Genotyping Techniques; HIV Infections; HIV-1; Humans; Male; Microbial Sensitivity Tests; Mutation; Nevirapine; Nitriles; pol Gene Products, Human Immunodeficiency Virus; Prevalence; Pyridazines; Pyrimidines; Rilpivirine; Treatment Failure; Young Adult	2018
Depression and Suicidal Ideation Among HIV-Infected Adults Receiving Efavirenz Versus Nevirapine in Uganda: A Prospective Cohort Study. Annals of internal medicine, 2018, 08-07, Volume: 169, Issue:3 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Depression; Female; HIV Infections; Humans; Male; Nevirapine; Prospective Studies; Suicidal Ideation; Uganda	2018
Using dried blood spots to facilitate therapeutic drug monitoring of antiretroviral drugs in resource-poor regions. The Journal of antimicrobial chemotherapy, 2018, 10-01, Volume: 73, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Alkynes; Anti-Retroviral Agents; Benzoxazines; Biological Transport; Cohort Studies; Cyclopropanes; Dried Blood Spot Testing; Drug Monitoring; Female; Health Resources; HIV Infections; HIV-1; Humans; Lopinavir; Male; Middle Aged; Nevirapine; Rural Population; Switzerland; Tanzania	2018
Nevirapine Concentrations During the First Month of Life and Maternal Efavirenz Washout in High-Risk HIV-Exposed Infants Receiving Triple Antiretroviral Prophylaxis. The Pediatric infectious disease journal, 2019, Volume: 38, Issue:2 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Chemoprevention; Cyclopropanes; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Longitudinal Studies; Male; Nevirapine; Plasma; Prospective Studies; Thailand	2019
Non-nucleoside reverse transcriptase inhibitors (NNRTIs)-induced Stevens-Johnson syndrome and gynecomastia in an HIV-infected child: A case report. Annales de dermatologie et de venereologie, 2018, Volume: 145, Issue:12 Topics: Adolescent; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Substitution; Gynecomastia; HIV Infections; Humans; Lamivudine; Male; Mucositis; Nevirapine; Reverse Transcriptase Inhibitors; Stevens-Johnson Syndrome	2018
Frequency of cross-resistance to rilpivirine and etravirine among HIV-1 subtype C infected individuals failing nevirapine/efavirenz based ART regimen. Infectious diseases (London, England), 2019, Volume: 51, Issue:1 Topics: Alkynes; Benzoxazines; Cyclopropanes; HIV Infections; HIV-1; Humans; Nevirapine; Nitriles; Pyridazines; Pyrimidines; Rilpivirine; Sweden	2019
Prevalence of predicted resistance to doravirine in HIV-1-positive patients after exposure to non-nucleoside reverse transcriptase inhibitors. International journal of antimicrobial agents, 2019, Volume: 53, Issue:4 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cross-Sectional Studies; Cyclopropanes; Delavirdine; Drug Resistance, Viral; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Male; Nevirapine; Nitriles; Pyridazines; Pyridones; Pyrimidines; Reverse Transcriptase Inhibitors; Rilpivirine; Treatment Outcome; Triazoles	2019
Rate of viral load change and adherence of HIV adult patients treated with Efavirenz or Nevirapine antiretroviral regimens at 24 and 48 weeks in Yaoundé, Cameroon: a longitudinal cohort study. BMC infectious diseases, 2019, Feb-26, Volume: 19, Issue:1 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cameroon; Cohort Studies; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Longitudinal Studies; Male; Middle Aged; Nevirapine; Patient Compliance; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome; Viral Load; Zidovudine	2019
Occurrence of CYP2B6 516G>T polymorphism in patients with ARV-associated hepatotoxicity. Molecular genetics & genomic medicine, 2019, Volume: 7, Issue:4 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Chemical and Drug Induced Liver Injury; Cyclopropanes; Cytochrome P-450 CYP2B6; Ethanol; Female; Humans; Male; Middle Aged; Nevirapine; Polymorphism, Single Nucleotide	2019
Measuring Adherence to Antiretroviral Therapy via Hair Concentrations in India. Journal of acquired immune deficiency syndromes (1999), 2019, 06-01, Volume: 81, Issue:2 Topics: Adolescent; Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Cohort Studies; Cyclopropanes; Drug Therapy, Combination; Female; Hair; HIV Seropositivity; Humans; India; Male; Medication Adherence; Nevirapine; San Francisco; Self Report; Young Adult	2019
Incidence and types of HIV-1 drug resistance mutation among patients failing first-line antiretroviral therapy. Journal of pharmacological sciences, 2019, Volume: 139, Issue:4 Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Antiviral Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Incidence; Lamivudine; Male; Middle Aged; Mutation; Nevirapine; Stavudine; Tenofovir; Treatment Failure; Viral Load; Zidovudine	2019
Viral suppression rate among children tested for HIV viral load at the Amhara Public Health Institute, Bahir Dar, Ethiopia. BMC infectious diseases, 2019, May-14, Volume: 19, Issue:1 Topics: Adolescent; Alkynes; Anti-Retroviral Agents; Benzoxazines; Child; Child, Preschool; Cross-Sectional Studies; Cyclopropanes; Ethiopia; Female; HIV Infections; Humans; Infant; Male; Nevirapine; Odds Ratio; Treatment Adherence and Compliance; Viral Load	2019
Nonnucleoside Reverse Transcriptase Inhibitor Hypersusceptibility and Resistance by Mutation of Residue 181 in HIV-1 Reverse Transcriptase. Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:8 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; Fluorescence Polarization; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Nevirapine; Reverse Transcriptase Inhibitors; Rilpivirine	2019
Non-nucleoside reverse transcriptase inhibitor levels among HIV-exposed uninfected infants at the time of HIV PCR testing - findings from a tertiary healthcare facility in Pretoria, South Africa. Journal of the International AIDS Society, 2019, Volume: 22, Issue:6 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Breast Feeding; Cohort Studies; Cyclopropanes; Female; HIV; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Male; Nevirapine; Polymerase Chain Reaction; Prospective Studies; Reverse Transcriptase Inhibitors; South Africa; Tertiary Healthcare	2019
Increasing body mass index or weight does not appear to influence the association between efavirenz-based antiretroviral therapy and implant effectiveness among HIV-positive women in western Kenya. Contraception, 2019, Volume: 100, Issue:4 Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Body Mass Index; Body Weight; Cohort Studies; Contraceptive Agents; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; Humans; Kenya; Male; Middle Aged; Nevirapine; Obesity; Overweight; Pregnancy; Pregnancy Rate; Treatment Outcome; Young Adult	2019
A pharmacokinetic and pharmacogenetic evaluation of contraceptive implants and antiretroviral therapy among women in Kenya and Uganda. AIDS (London, England), 2019, 11-01, Volume: 33, Issue:13 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Contraceptive Agents, Female; Cyclopropanes; Desogestrel; Drug Antagonism; Female; HIV Infections; Humans; Kenya; Levonorgestrel; Linear Models; Nevirapine; Pharmacogenomic Testing; Uganda	2019
Trend of HIV transmitted drug resistance before and after implementation of HAART regimen restriction in the treatment of HIV-1 infected patients in southern Taiwan. BMC infectious diseases, 2019, Aug-23, Volume: 19, Issue:1 Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Combinations; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Mutation; Nevirapine; Prevalence; Reverse Transcriptase Inhibitors; Taiwan; Zidovudine	2019
Pediatric Antiretroviral Therapeutic Drug Monitoring: A Five and a Half Year Experience from a South African Tertiary Hospital. Journal of tropical pediatrics, 2020, 08-01, Volume: 66, Issue:4 Topics: Adolescent; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Child; Child, Preschool; Cyclopropanes; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Female; HIV Infections; Humans; Lopinavir; Male; Medication Adherence; Nevirapine; Pregnancy; Retrospective Studies; South Africa; Tertiary Care Centers; Treatment Outcome	2020
'High' antiretroviral deintensification strategy and cellular HIV DNA levels. Journal of chemotherapy (Florence, Italy), 2020, Volume: 32, Issue:1 Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; DNA, Viral; HIV Infections; HIV-1; Humans; Lamivudine; Nevirapine; Pilot Projects	2020
Incidence and predictors of nevirapine and efavirenz-associated rash among Indonesian HIV patients. Asian Pacific journal of allergy and immunology, 2022, Volume: 40, Issue:2 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Coinfection; Cyclopropanes; Exanthema; Female; Hepatitis C; HIV Infections; Humans; Incidence; Indonesia; Male; Nevirapine; Retrospective Studies	2022
Effect of nevirapine, efavirenz and lopinavir/ritonavir on the therapeutic concentration and toxicity of lumefantrine in people living with HIV at Lagos University Teaching Hospital, Nigeria. Journal of pharmacological sciences, 2020, Volume: 144, Issue:3 Topics: Adult; Alkynes; Anti-Retroviral Agents; Antimalarials; Artemether, Lumefantrine Drug Combination; Benzoxazines; Cyclopropanes; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; Humans; Lopinavir; Malaria; Male; Middle Aged; Nevirapine; Nigeria; Ritonavir; Treatment Outcome; Young Adult	2020
High-resolution view of HIV-1 reverse transcriptase initiation complexes and inhibition by NNRTI drugs. Nature communications, 2021, 05-04, Volume: 12, Issue:1 Topics: Alkynes; Benzoxazines; Catalytic Domain; Cryoelectron Microscopy; Cyclopropanes; HIV Reverse Transcriptase; HIV-1; Models, Molecular; Nevirapine; Nucleic Acid Conformation; Reverse Transcriptase Inhibitors; RNA, Transfer, Lys; RNA, Viral	2021
Association between social psychological status and efavirenz and nevirapine plasma concentration among HIV patients in Kenya. Scientific reports, 2021, 11-11, Volume: 11, Issue:1 Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cross-Sectional Studies; Cyclopropanes; Female; HIV Infections; Humans; Kenya; Male; Middle Aged; Nevirapine; Socioeconomic Factors; Young Adult	2021
The role of CYP2B6 516G>T polymorphism on efavirenz/nevirapine toxicity. Implications on treatment outcomes: Lessons from Botswana. Medicine, 2022, Apr-29, Volume: 101, Issue:17 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Botswana; Cyclopropanes; Cytochrome P-450 CYP2B6; Genotype; HIV Infections; Humans; Leukocytes, Mononuclear; Nevirapine; Polymorphism, Single Nucleotide; Retrospective Studies; Reverse Transcriptase Inhibitors	2022
Population Pharmacokinetic Modeling and Simulation of Rifapentine Supports Concomitant Antiretroviral Therapy with Efavirenz and Non-Weight Based Dosing. Antimicrobial agents and chemotherapy, 2022, 09-20, Volume: 66, Issue:9 Topics: Alkynes; Anti-Retroviral Agents; Antitubercular Agents; Benzoxazines; Cyclopropanes; HIV Infections; Humans; Isoniazid; Nevirapine; Rifampin	2022
Maraviroc Population Pharmacokinetics Within the First 6 Weeks of Life. The Pediatric infectious disease journal, 2022, 11-01, Volume: 41, Issue:11 Topics: Adult; Alkynes; Benzoxazines; Cyclopropanes; HIV Infections; Humans; Infant; Infant, Newborn; Maraviroc; Nevirapine	2022
Contraceptive implant use duration is not associated with breakthrough pregnancy among women living with HIV and using efavirenz: a retrospective, longitudinal analysis. Journal of the International AIDS Society, 2022, Volume: 25, Issue:9 Topics: Adolescent; Adult; Alkynes; Benzoxazines; Contraceptive Agents; Cyclopropanes; Female; HIV Infections; Humans; Levonorgestrel; Middle Aged; Nevirapine; Pregnancy; Retrospective Studies; Young Adult	2022
Impact of Drug Exposure on Resistance Selection Following Artemether-Lumefantrine Treatment for Malaria in Children With and Without HIV in Uganda. Clinical pharmacology and therapeutics, 2023, Volume: 113, Issue:3 Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Drug Combinations; Fluorenes; HIV Infections; Humans; Lopinavir; Lumefantrine; Malaria; Malaria, Falciparum; Nevirapine; Ritonavir; Uganda	2023
Case study on antiretroviral drugs uptake from soil irrigated with contaminated water: Bio-accumulation and bio-translocation to roots, stem, leaves, and fruits. Environmental pollution (Barking, Essex : 1987), 2023, Feb-15, Volume: 319 Topics: Bioaccumulation; Fruit; HIV Infections; Humans; Nevirapine; Soil; Soil Pollutants; Vegetables; Water; Water Pollution	2023
Methods optimization and application: Solid phase extraction, ultrasonic extraction and Soxhlet extraction for the determination of antiretroviral drugs in river water, wastewater, sludge, soil and sediment. Journal of pharmaceutical and biomedical analysis, 2023, Jun-15, Volume: 230 Topics: Ecosystem; HIV Infections; Humans; Nevirapine; Rivers; Sewage; Soil; Solid Phase Extraction; Ultrasonics; Wastewater; Water; Water Pollutants, Chemical	2023
Prevalence of pretreatment drug resistance in persons initiating and reinitiating antiretroviral therapy in Sri Lanka: results from a national representative survey. The Journal of antimicrobial chemotherapy, 2023, 06-01, Volume: 78, Issue:6 Topics: Adult; Anti-HIV Agents; Anti-Retroviral Agents; Cross-Sectional Studies; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Homosexuality, Male; Humans; Male; Mutation; Nevirapine; Prevalence; Sexual and Gender Minorities; Sri Lanka	2023
Optimizing antiretroviral therapy for children living with HIV: Experience from an observational cohort in Lesotho. PloS one, 2023, Volume: 18, Issue:7 Topics: Anti-HIV Agents; Child; Child, Preschool; Female; HIV Infections; Humans; Infant; Lesotho; Lopinavir; Male; Nevirapine; Retrospective Studies; Ritonavir; Viral Load	2023
Associations of modern initial antiretroviral therapy regimens with all-cause mortality in people living with HIV in resource-limited settings: a retrospective multicenter cohort study in China. Nature communications, 2023, 09-02, Volume: 14, Issue:1 Topics: Acquired Immunodeficiency Syndrome; Benzoxazines; China; Cohort Studies; Humans; Lopinavir; Nevirapine; Retrospective Studies	2023