Compounds > nevirapine

nevirapine and delavirdine mesylate

nevirapine has been researched along with delavirdine mesylate in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.67)18.2507
2000's5 (33.33)29.6817
2010's9 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adams, WJ; Biles, C; Evans, DB; Friis, JM; Hosley, JD; Keiser, BJ; Kopta, LA; Morge, RA; Morris, J; Olmsted, RA; Poel, TJ; Romero, DL; Sharma, SK; Stefanski, KJ; Stehle, RG; Tarpley, WG; Thomas, RC; Voorman, RL; Wishka, DG; Yagi, Y1
Corbett, JW; Cordova, BC; Erickson-Viitanen, SK; Gearhart, LA; Klabe, RM; Ko, SS; Rodgers, JD1
Biles, C; Genin, MJ; Keiser, BJ; Poppe, SM; Romero, DL; Swaney, SM; Tarpley, WG; Yagi, Y1
Mao, C; Sudbeck, EA; Uckun, FM; Venkatachalam, TK1
Andries, K; Arnold, E; Azijn, H; de Béthune, MP; De Clercq, E; Grous, PG; Janssen, PA; Krishnan, S; Kukla, MJ; Ludovici, DW; Pauwels, R1
Boel, AM; Dahan, B; El-Brollosy, NR; Jørgensen, PT; Nielsen, C; Pedersen, EB1
Chen, W; Chen, X; De Clercq, E; Li, D; Li, X; Liu, X; Pannecouque, C; Tian, Y; Zhan, P1
Balzarini, J; Chen, X; De Clercq, E; Liu, X; Pannecouque, C; Zhan, P1
Chen, X; Cheng, Z; De Clercq, E; Liu, X; Meng, C; Pannecouque, C; Shao, S; Zhan, P1
Balzarini, J; Chen, X; De Clercq, E; Liu, H; Liu, X; Meng, Q; Pannecouque, C; Wang, D1
Chen, W; De Clercq, E; Liu, X; Liu, Z; Pannecouque, C; Zhan, P1
Balzarini, J; Chen, W; De Clercq, E; Fu, L; Huang, B; Li, C; Liu, H; Liu, T; Liu, X; Pannecouque, C; Sun, Y; Yu, M; Zhan, P1
Chen, W; De Clercq, E; Fu, L; Huang, B; Li, C; Li, X; Liang, X; Liu, H; Liu, T; Liu, X; Pannecouque, C; Sun, Y; Zhan, P1
Chen, X; Daelemans, D; De Clercq, E; Huang, B; Kang, D; Li, W; Liu, X; Meng, Q; Pannecouque, C; Zhan, P1
De Clercq, E; Huo, Z; Kang, D; Liu, H; Liu, X; Pannecouque, C; Tian, Y; Zhan, P; Zhang, H; Zhou, Z1

Other Studies

15 other study(ies) available for nevirapine and delavirdine mesylate

ArticleYear
Targeting delavirdine/atevirdine resistant HIV-1: identification of (alkylamino)piperidine-containing bis(heteroaryl)piperazines as broad spectrum HIV-1 reverse transcriptase inhibitors.
    Journal of medicinal chemistry, 1996, Sep-13, Volume: 39, Issue:19

    Topics: Animals; Anti-HIV Agents; Biological Availability; Cell Line; Delavirdine; Drug Resistance, Microbial; Drug Stability; HIV Reverse Transcriptase; HIV-1; Indoles; Molecular Structure; Piperazines; Piperidines; Pyridines; Rats; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

1996
Novel 2,2-dioxide-4,4-disubstituted-1,3-H-2,1,3-benzothiadiazines as non-nucleoside reverse transcriptase inhibitors.
    Bioorganic & medicinal chemistry letters, 2000, Jan-17, Volume: 10, Issue:2

    Topics: Benzothiadiazines; HIV-1; Humans; Molecular Structure; Reverse Transcriptase Inhibitors

2000
Novel 1,5-diphenylpyrazole nonnucleoside HIV-1 reverse transcriptase inhibitors with enhanced activity versus the delavirdine-resistant P236L mutant: lead identification and SAR of 3- and 4-substituted derivatives.
    Journal of medicinal chemistry, 2000, Mar-09, Volume: 43, Issue:5

    Topics: Anti-HIV Agents; Delavirdine; Drug Resistance, Microbial; HIV Reverse Transcriptase; Mutation; Pyrazoles; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2000
Anti-HIV activity of aromatic and heterocyclic thiazolyl thiourea compounds.
    Bioorganic & medicinal chemistry letters, 2001, Feb-26, Volume: 11, Issue:4

    Topics: Anti-HIV Agents; HIV Reverse Transcriptase; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thiazoles; Thiourea; Virus Replication

2001
Evolution of anti-HIV drug candidates. Part 1: From alpha-anilinophenylacetamide (alpha-APA) to imidoyl thiourea (ITU).
    Bioorganic & medicinal chemistry letters, 2001, Sep-03, Volume: 11, Issue:17

    Topics: Acetamides; Acetophenones; Aniline Compounds; Anti-HIV Agents; Drug Design; Drug Evaluation, Preclinical; Drug Stability; HIV Reverse Transcriptase; HIV-1; Imines; Structure-Activity Relationship; Thiourea

2001
Synthesis of novel N-1 (allyloxymethyl) analogues of 6-benzyl-1-(ethoxymethyl)-5-isopropyluracil (MKC-442, emivirine) with improved activity against HIV-1 and its mutants.
    Journal of medicinal chemistry, 2002, Dec-19, Volume: 45, Issue:26

    Topics: Anti-HIV Agents; Cell Line; HIV-1; Humans; Magnetic Resonance Spectroscopy; Mutation; Stereoisomerism; Structure-Activity Relationship; Uracil; Virus Replication

2002
Arylazolylthioacetanilide. Part 8: Design, synthesis and biological evaluation of novel 2-(2-(2,4-dichlorophenyl)-2H-1,2,4-triazol-3-ylthio)-N-arylacetamides as potent HIV-1 inhibitors.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:10

    Topics: Acetamides; Anti-HIV Agents; Cell Line; HIV Infections; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Triazoles; Virus Replication

2011
Synthesis and biological evaluation of piperidine-substituted triazine derivatives as HIV-1 non-nucleoside reverse transcriptase inhibitors.
    European journal of medicinal chemistry, 2012, Volume: 51

    Topics: Anti-HIV Agents; Cell Line; Chemistry Techniques, Synthetic; HIV Reverse Transcriptase; HIV-1; Inhibitory Concentration 50; Piperidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Triazines

2012
Design, synthesis, anti-HIV evaluation and molecular modeling of piperidine-linked amino-triazine derivatives as potent non-nucleoside reverse transcriptase inhibitors.
    Bioorganic & medicinal chemistry, 2012, Jun-15, Volume: 20, Issue:12

    Topics: Amines; Anti-HIV Agents; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Design; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Piperidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Triazines

2012
Novel piperidinylamino-diarylpyrimidine derivatives with dual structural conformations as potent HIV-1 non-nucleoside reverse transcriptase inhibitors.
    Bioorganic & medicinal chemistry letters, 2013, Dec-15, Volume: 23, Issue:24

    Topics: Binding Sites; Drug Resistance, Viral; Enzyme Activation; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Docking Simulation; Protein Binding; Protein Structure, Tertiary; Pyrimidines; Reverse Transcriptase Inhibitors

2013
Design, synthesis and anti-HIV evaluation of novel diarylnicotinamide derivatives (DANAs) targeting the entrance channel of the NNRTI binding pocket through structure-guided molecular hybridization.
    European journal of medicinal chemistry, 2014, Nov-24, Volume: 87

    Topics: Anti-HIV Agents; Catalytic Domain; Dose-Response Relationship, Drug; Drug Design; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Molecular Structure; Niacinamide; Protein Conformation; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Tumor Cells, Cultured

2014
Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 3: optimization of [1,2,4]triazolo[1,5-a]pyrimidine core via structure-based and physicochemical property-driven approaches.
    European journal of medicinal chemistry, 2015, Mar-06, Volume: 92

    Topics: Anti-HIV Agents; Cell Line, Tumor; Dose-Response Relationship, Drug; Heterocyclic Compounds; Heterocyclic Compounds, 2-Ring; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Nitrogen; Reverse Transcriptase Inhibitors; Solubility; Structure-Activity Relationship; Sulfones

2015
Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 4: design, synthesis and biological evaluation of novel imidazo[1,2-a]pyrazines.
    European journal of medicinal chemistry, 2015, Mar-26, Volume: 93

    Topics: Anti-HIV Agents; Chemistry Techniques, Synthetic; Computational Biology; Drug Design; HIV Reverse Transcriptase; HIV-1; Imidazoles; Molecular Docking Simulation; Protein Conformation; Pyrazines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2015
Design, synthesis and evaluation of novel HIV-1 NNRTIs with dual structural conformations targeting the entrance channel of the NNRTI binding pocket.
    European journal of medicinal chemistry, 2016, Jun-10, Volume: 115

    Topics: Anti-HIV Agents; Binding Sites; Dose-Response Relationship, Drug; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Virus Replication

2016
Discovery of uracil-bearing DAPYs derivatives as novel HIV-1 NNRTIs via crystallographic overlay-based molecular hybridization.
    European journal of medicinal chemistry, 2017, Apr-21, Volume: 130

    Topics: Animals; Anti-HIV Agents; Cell Line; Drug Discovery; HIV Reverse Transcriptase; HIV-1; Mice; Models, Molecular; Reverse Transcriptase Inhibitors; Solubility; Structure-Activity Relationship; Uracil

2017