nevirapine and carbamazepine

nevirapine has been researched along with carbamazepine in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (29.63)29.6817
2010's18 (66.67)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Ariyoshi, N; Igarashi, T; Ishii, I; Kitada, M; Nakamura, H; Nakasa, H; Ohmori, S1
Ariyoshi, N; Hata, M; Igarashi, T; Imada, H; Ishii, I; Kitada, M; Nakamura, H; Ohmori, S; Torimoto, N1
Burger, DM; Droste, JA; Hekster, YA; Koopmans, PP1
Faucette, SR; LeCluyse, EL; Moore, R; Negishi, M; Omiecinski, CJ; Sueyoshi, T; Wang, H; Zhang, TC1
Aitken, SC; Burger, DM; Dolmans, W; Fillekes, Q; Gibb, DM; Kisanga, ER; L'homme, R; Mariki, G; Muro, EP; Schuurman, R; Van der Ven, AJ; Walker, AS1
Karlin, E; Phillips, E1
Baranyai, D; Burger, D; Diczfalusy, U; Fillekes, Q; Gödtel-Armbrust, U; Kisanga, E; Muro, E; Schirmer, MA; Schuurman, R; Wojnowski, L1
Mushiroda, T1
Borroni, RG1
Fricke-Galindo, I; LLerena, A; López-López, M1
Avdeef, A1
Chimuka, L; Khulu, S; Madikizela, LM; Mavhunga, E; Ncube, S; Nuapia, Y1

Reviews

5 review(s) available for nevirapine and carbamazepine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Genotyping for severe drug hypersensitivity.
    Current allergy and asthma reports, 2014, Volume: 14, Issue:3

    Topics: Allopurinol; Amoxicillin-Potassium Clavulanate Combination; Carbamazepine; Dideoxynucleosides; Drug Hypersensitivity; Genotype; HLA-B Antigens; Humans; Nevirapine; Pharmacogenetics; Protein Conformation; Stevens-Johnson Syndrome

2014
[Future direction of pharmacogenomics: identification of genes associated with risk of adverse drug reactions using genome-wide association study].
    Rinsho byori. The Japanese journal of clinical pathology, 2014, Volume: 62, Issue:1

    Topics: Anticonvulsants; Carbamazepine; Dideoxynucleosides; Drug Eruptions; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotyping Techniques; HLA Antigens; Humans; Intracellular Signaling Peptides and Proteins; Nevirapine; Pharmacogenetics; Polymorphism, Genetic; Risk

2014
Pharmacogenetic markers of severe cutaneous adverse drug reactions.
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2014, Volume: 149, Issue:2

    Topics: Allopurinol; Anti-HIV Agents; Anticonvulsants; Biomarkers; Carbamazepine; Dideoxynucleosides; Drug Eruptions; Drug Hypersensitivity Syndrome; Enzyme Inhibitors; Genes, MHC Class I; Genome-Wide Association Study; Genotype; HLA Antigens; Humans; Nevirapine; Pharmacogenetics; Polymorphism, Single Nucleotide; Stevens-Johnson Syndrome

2014
An update on HLA alleles associated with adverse drug reactions.
    Drug metabolism and personalized therapy, 2017, 05-24, Volume: 32, Issue:2

    Topics: Alleles; Allopurinol; Carbamazepine; Dideoxynucleosides; Drug-Related Side Effects and Adverse Reactions; Economics, Pharmaceutical; HLA Antigens; Humans; Nevirapine

2017

Trials

1 trial(s) available for nevirapine and carbamazepine

ArticleYear
Intrapartum single-dose carbamazepine reduces nevirapine levels faster and may decrease resistance after a single dose of nevirapine for perinatal HIV prevention.
    Journal of acquired immune deficiency syndromes (1999), 2012, Mar-01, Volume: 59, Issue:3

    Topics: Adolescent; Adult; Carbamazepine; CD4 Lymphocyte Count; Chi-Square Distribution; Drug Interactions; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Mutation; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; RNA, Viral; Young Adult

2012

Other Studies

21 other study(ies) available for nevirapine and carbamazepine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Glutathione; Pharmacology; Sulfur Radioisotopes

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Effects of endogenous steroids on CYP3A4-mediated drug metabolism by human liver microsomes.
    Drug metabolism and disposition: the biological fate of chemicals, 2002, Volume: 30, Issue:5

    Topics: Adult; Carbamazepine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Epoxy Compounds; Erythromycin; Humans; Hydroxylation; In Vitro Techniques; Isoxazoles; Kinetics; Microsomes, Liver; Mixed Function Oxygenases; Nevirapine; Pharmaceutical Preparations; Phenols; Steroids; Sulfonamides; Triazolam; Zonisamide

2002
Direct interaction between substrates and endogenous steroids in the active site may change the activity of cytochrome P450 3A4.
    Biochemistry, 2003, Dec-30, Volume: 42, Issue:51

    Topics: Adult; Aldosterone; Androstenedione; Binding Sites; Carbamazepine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Stability; Estradiol; Humans; Hydroxylation; Kinetics; Mutation; Nevirapine; Serine; Substrate Specificity

2003
TDM: therapeutic drug measuring or therapeutic drug monitoring?
    Therapeutic drug monitoring, 2005, Volume: 27, Issue:4

    Topics: Anti-Retroviral Agents; Carbamazepine; Drug Interactions; Drug Monitoring; Drug Resistance, Viral; HIV Infections; Humans; Indinavir; Nelfinavir; Nevirapine; Patient Compliance; Quality Control; Surveys and Questionnaires

2005
Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 320, Issue:1

    Topics: Alkynes; Animals; Aryl Hydrocarbon Hydroxylases; Benzoxazines; Carbamazepine; Cells, Cultured; Constitutive Androstane Receptor; Cyclopropanes; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Gene Expression Regulation, Enzymologic; Hepatocytes; Humans; Mice; Nevirapine; Oxazines; Oxidoreductases, N-Demethylating; Pregnane X Receptor; Protein Transport; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Transcription Factors; Transcriptional Activation

2007
Reduction of nevirapine-driven HIV mutations by carbamazepine is modulated by CYP3A activity.
    The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:7

    Topics: Anti-HIV Agents; Carbamazepine; Chemoprevention; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Mutation, Missense; Nevirapine; Pregnancy; Treatment Outcome

2014
Cocrystal solubility product analysis - Dual concentration-pH mass action model not dependent on explicit solubility equations.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2017, Dec-15, Volume: 110

    Topics: Amines; Carbamazepine; Chemistry, Pharmaceutical; Crystallization; Cyclohexanecarboxylic Acids; Drug Stability; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydrogen-Ion Concentration; Indomethacin; Models, Molecular; Molecular Conformation; Nevirapine; Osmolar Concentration; Solubility; Thermodynamics

2017
Development and application of a membrane assisted solvent extraction-molecularly imprinted polymer based passive sampler for monitoring of selected pharmaceuticals in surface water.
    Water research, 2022, Oct-15, Volume: 225

    Topics: Carbamazepine; Environmental Monitoring; Etilefrine; Ionic Liquids; Methocarbamol; Molecularly Imprinted Polymers; Nevirapine; Pharmaceutical Preparations; South Africa; Venlafaxine Hydrochloride; Water; Water Pollutants, Chemical

2022