Compounds > nevirapine

nevirapine and acetylcysteine

nevirapine has been researched along with acetylcysteine in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's6 (66.67)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Chaponda, M; Lian, LY; Maggs, JL; Park, BK; Pirmohamed, M; Srivastava, A; Williams, DP1
Antunes, AM; Beland, FA; Godinho, AL; Justino, GC; Marques, MM; Martins, IL1
Antunes, AMM; Castro, MF; Cipriano, M; Harjivan, SG; Jacob, CC; Marinho, AT; Marques, MM; Martins, IL; Miranda, JP; Oliveira, NG; Pereira, SA; Pinheiro, PF1

Reviews

1 review(s) available for nevirapine and acetylcysteine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

8 other study(ies) available for nevirapine and acetylcysteine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Quantifying the metabolic activation of nevirapine in patients by integrated applications of NMR and mass spectrometries.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:1

    Topics: Acetylcysteine; Adult; Animals; Bile; Biomarkers; Biotransformation; Chromatography, High Pressure Liquid; Dexamethasone; Female; Glucuronic Acid; Glutathione; Hepatocytes; Humans; Liver; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Microsomes, Liver; Middle Aged; Molecular Structure; Nevirapine; Rats; Rats, Inbred BN; Rats, Wistar; Urine

2010
Amino acid adduct formation by the nevirapine metabolite, 12-hydroxynevirapine--a possible factor in nevirapine toxicity.
    Chemical research in toxicology, 2010, May-17, Volume: 23, Issue:5

    Topics: Acetylcysteine; Amino Acids; Glutathione; Histidine; Humans; Mesylates; Nevirapine; Reverse Transcriptase Inhibitors; Spectrometry, Mass, Electrospray Ionization; Tryptophan

2010
Hepatocyte spheroids as a competent in vitro system for drug biotransformation studies: nevirapine as a bioactivation case study.
    Archives of toxicology, 2017, Volume: 91, Issue:3

    Topics: Acetylcysteine; Animals; Arylsulfotransferase; Biotransformation; Cell Culture Techniques; Hepatocytes; Inactivation, Metabolic; Nevirapine; Rats; Reproducibility of Results; Spheroids, Cellular

2017