Page last updated: 2024-09-03

neurotensin (8-13) and neurotensin

neurotensin (8-13) has been researched along with neurotensin in 65 studies

Compound Research Comparison

Studies
(neurotensin (8-13))
Trials
(neurotensin (8-13))
Recent Studies (post-2010)
(neurotensin (8-13))
Studies
(neurotensin)
Trials
(neurotensin)
Recent Studies (post-2010) (neurotensin)
660104,05445544

Protein Interaction Comparison

ProteinTaxonomyneurotensin (8-13) (IC50)neurotensin (IC50)
Neurotensin receptor type 1Homo sapiens (human)0.0013
Neurotensin receptor type 2Rattus norvegicus (Norway rat)0.0582
SortilinHomo sapiens (human)0.36

Research

Studies (65)

TimeframeStudies, this research(%)All Research%
pre-19903 (4.62)18.7374
1990's21 (32.31)18.2507
2000's29 (44.62)29.6817
2010's12 (18.46)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Machida, R; Tsushima, Y; Watanabe, S; Yamakawa, I1
Bloom, SR; Domin, J; Lee, YC; Spokes, RA; Yiangou, Y1
Di Paola, ED; Richelson, E1
Cubeddu, LX; Faggin, BM1
Enloe, LJ; Gilbert, JA; Kanba, KS; McCormick, DJ; Moore, A; Pfenning, MA; Richelson, E1
Kanba, KS; Kanba, S; Nelson, A; Okazaki, H; Richelson, E1
Emson, P; Markstein, R1
Bianchi, C; Ferraro, L; Fuxe, K; O'Connor, WT; Tanganelli, S; Ungerstedt, U1
García-López, MT; Gómez-Monterrey, I; González-Muñiz, R; Herranz, R; Jimeno, ML; Johansen, NL; Madsen, K; Suárez-Gea, ML; Suzdak, P; Thøgersen, H1
Bougault, I; Brun, P; Le Fur, G; Leyris, R; Soubrié, P; Souilhac, J; Steinberg, R1
Meaney, MJ; Quirion, R; Rowe, W; Viau, V1
Gao, GC; Wei, ET2
Fuxe, K; Hedlund, PB; Li, XM1
Pinnock, RD; Woodruff, GN1
Gratton, A; Rompré, PP1
Finnman, UB; Fuxe, K; Hedlund, PB; Li, XM; Von Euler, G1
Cusack, B; Groshan, K; Pang, YP; Richelson, E1
Hayashi, Y; Itano, T; Lu, YF; Matsui, H; Moriwaki, A; Tomizawa, K1
Ma, RC; Szurszewski, JH1
Antonelli, T; Ferraro, L; Fuxe, K; O'Connor, WT; Tanganelli, S1
Câmpian, E; Dóda, M; Furka, A; Illyés, E; Kindla, K; Mák, M; Rapp, W; Sebestyén, F; Szegö, P; Szendrei, G; Szókán, G1
Cusack, B; Douglas, CL; Fauq, A; McCormick, DJ; Pang, YP; Richelson, E; Stewart, JA; Tyler, BM1
Dix, TA; Lundquist, JT1
Kruse, CG; Long, SK; Nievelstein, H; Wadman, WJ; Werkman, TR1
Farinas, F; McCormick, DJ; Richelson, E; Stewart, JA; Tyler-McMahon, BM1
Trudeau, LE1
Brun, P; Leonetti, M; Renaud, B; Sotty, F; Soubrié, P; Steinberg, R; Suaud-Chagny, MF1
Chou, T; Cusack, B; Jansen, K; McCormick, DJ; Pang, Y; Richelson, E1
Anderson, RM; Fatigati, MD; Rompré, P1
Belmeguenai, A; Cavelier, F; Leprince, J; Louiset, E; Martinez, J; Vaudry, H; Vivet, B1
Allemann-Tannahill, L; Bläuenstein, P; Carrel-Rémy, N; Conrath, P; García-Garayoa, E; Iterbeke, K; Schubiger, PA; Tourwé, D; Willmann, M1
Bergmann, R; Chavatte, K; Heichert, C; Iterbeke, K; Johannsen, B; Kretzschmar, M; Mäding, P; Reubi, JC; Rodig, H; Scheunemann, M; Tourwé, D; Wittrisch, H; Zips, D1
Blanc, A; Bläuenstein, P; Bruehlmeier, M; Conrath, P; García-Garayoa, E; Iterbeke, K; Schubiger, PA; Tourwé, D1
Aubry, A; Cavelier, F; Didierjean, C; Marraud, M; Martinez, J; Vicherat, A; Vivet, B1
Büllesbach, EE; Dix, TA; Golden, PL; Lundquist, JT1
Congar, P; Legault, M; Michel, FJ; Trudeau, LE1
Bains, S; Chung, C; Cooke, R; Watts, A; Williamson, PT1
Gjerde, EA; Reed, RK; Wei, ET1
Dix, TA; Kokko, KP1
Cusack, B; Hong, F; Richelson, E; Zaidi, J1
Sato, M; Suzuki, Y; Yanai, T1
Dix, TA; Hadden, MK; Kokko, KP; Mazella, J; Orwig, KS2
Calderon, DP; Leverkova, N; Peinado, A1
Dix, TA; Hadden, MK; Kokko, KP; Orwig, KS; Price, KL; See, RE1
Bläuenstein, P; Garcia-Garayoa, E; Maes, V; Tourwé, D1
An, R; Aruva, MR; Gao, Z; Zhang, K; Zhang, Y1
Bergmann, R; Hultsch, C; Pawelke, B; Wuest, F1
Bergmann, R; Berndt, M; Hultsch, C; Wuest, F1
Kalivas, PW; Torregrossa, MM1
Chen, G; Chen, Y; Xu, L; Zhang, L1
Dix, TA; Hadden, MK; Lassetter, MR; Orwig, KS1
Bergmann, R; Kniess, T; Pietzsch, J; Ramenda, T; Richter, S; Steinbach, J; Wuest, F1
Brower, JO; Cash, M; Dix, TA; Hughes, FM; Massa, F; May, LA; Mazella, J; Morrow, D; Shaner, BE; Woods, RJ; Zotian, L1
Faintuch, BL; Núñez, EG; Queiróz, RG; Teodoro, R1
Accardo, A; Bracci, L; Brunetti, J; Falciani, C; Lelli, B; Morelli, G; Pini, A; Tesauro, D1
Cai, Z; Chen, G; Liu, X; Wang, L; Xia, S; Xu, H; Xu, X; Ye, H; Yu, L; Zheng, C1
Cherniakova, IV; Gudasheva, TA; Klodt, PM; Kolik, LG; Konstantinopol'skiĭ, MA; Kudrin, VS1
Beckstead, MJ; Branch, SY; Courtney, NA; Ford, CP; Piccart, E1
Mascarin, A; Mindt, TL; Valverde, IE; Vomstein, S1
Bernhardt, G; Biselli, S; Buschauer, A; Cabrele, C; Einsiedel, J; Gmeiner, P; Hübner, H; Keller, M; Kuhn, KK; Mollereau, C; Svobodová, J; Vanderheyden, PM; Wifling, D1
Andrzejewski, K; Jampolska, M; Kaczyńska, K; Kleczkowska, P; Kogut, E; Lipkowski, AW; Sulejczak, D; Zając, D1
Besserer-Offroy, É; Brouillette, RL; Leduc, R; Longpré, JM; Marsault, É; Sarret, P; Sousbie, M; Vivancos, M1
Blais, V; Côté, J; Eiselt, E; Gendron, L; Longpré, JM; Sarret, P1

Reviews

1 review(s) available for neurotensin (8-13) and neurotensin

ArticleYear
Coloured peptides: synthesis, properties and use in preparation of peptide sub-library kits.
    Journal of peptide science : an official publication of the European Peptide Society, 1998, Volume: 4, Issue:4

    Topics: Aminobenzoates; Color; Mass Spectrometry; Molecular Structure; Neurotensin; para-Aminobenzoates; Peptide Fragments; Peptide Library; Peptides; Solubility

1998

Other Studies

64 other study(ies) available for neurotensin (8-13) and neurotensin

ArticleYear
Preparation of neurotensin analogue-containing poly(dl-lactic acid) microspheres formed by oil-in-water solvent evaporation.
    Journal of pharmaceutical sciences, 1992, Volume: 81, Issue:9

    Topics: Amino Acid Sequence; Lactates; Lactic Acid; Microspheres; Molecular Sequence Data; Neurotensin; Oligopeptides; Peptide Fragments; Polyesters; Polymers; Solvents

1992
Comparison of neuromedin-N and neurotensin on net fluid flux across rat small intestine.
    European journal of pharmacology, 1990, Jan-03, Volume: 175, Issue:1

    Topics: Amino Acid Sequence; Animals; Body Fluids; Drug Synergism; Female; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Molecular Sequence Data; Neurotensin; Peptide Fragments; Rats; Rats, Inbred Strains

1990
Cardiovascular effects of neurotensin and some analogues on rats.
    European journal of pharmacology, 1990, Jan-17, Volume: 175, Issue:3

    Topics: Animals; Aorta, Thoracic; Blood Pressure; Hemodynamics; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Neurotensin; Peptide Fragments; Rats; Structure-Activity Relationship; Vasodilation

1990
Rapid desensitization of dopamine release induced by neurotensin and neurotensin fragments.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 253, Issue:2

    Topics: Animals; Calcium; Corpus Striatum; Culture Techniques; Dopamine; Drug Interactions; Male; Neurotensin; Peptide Fragments; Potassium; Rabbits; Tritium

1990
Neurotensin(8-13): comparison of novel analogs for stimulation of cyclic GMP formation in neuroblastoma clone N1E-115 and receptor binding to human brain and intact N1E-115 cells.
    Biochemical pharmacology, 1989, Oct-01, Volume: 38, Issue:19

    Topics: Brain; Cyclic GMP; Humans; Neuroblastoma; Neurotensin; Peptide Fragments; Receptors, Neurotensin; Receptors, Neurotransmitter; Structure-Activity Relationship; Tumor Cells, Cultured

1989
[3H]neurotensin(8-13) binds in human brain to the same sites as does [3H]neurotensin but with higher affinity.
    Journal of neurochemistry, 1988, Volume: 50, Issue:1

    Topics: Aged; Binding, Competitive; Brain; Cell Membrane; Female; Frontal Lobe; Humans; Kinetics; Male; Middle Aged; Neurotensin; Peptide Fragments; Receptors, Neurotensin; Receptors, Neurotransmitter; Tissue Distribution; Tritium

1988
Effect of neurotensin and its fragments neurotensin-(1-6) and neurotensin-(8-13) on dopamine release from cat striatum.
    European journal of pharmacology, 1988, Jul-26, Volume: 152, Issue:1-2

    Topics: Animals; Bacitracin; Cats; Corpus Striatum; Dopamine; Female; In Vitro Techniques; Male; Neurotensin; Nomifensine; Peptide Fragments; Tetrodotoxin

1988
Neurotensin increases endogenous glutamate release in the neostriatum of the awake rat.
    Synapse (New York, N.Y.), 1995, Volume: 20, Issue:4

    Topics: Animals; Corpus Striatum; Glutamic Acid; Male; Microdialysis; Neurotensin; Peptide Fragments; Rats; Rats, Sprague-Dawley

1995
Ketomethylene and (cyanomethylene)amino pseudopeptide analogues of the C-terminal hexapeptide of neurotensin.
    Journal of medicinal chemistry, 1995, Mar-17, Volume: 38, Issue:6

    Topics: Acetonitriles; Amino Acid Sequence; Animals; Cerebral Cortex; Ketones; Molecular Sequence Data; Neurotensin; Oligopeptides; Peptide Fragments; Rats

1995
Neurochemical and behavioural effects of neurotensin vs [D-Tyr11]neurotensin on mesolimbic dopaminergic function.
    Neuropeptides, 1995, Volume: 28, Issue:1

    Topics: Animals; Behavior, Animal; Dopamine; Dose-Response Relationship, Drug; Male; Neurotensin; Nucleus Accumbens; Peptide Fragments; Rats; Rats, Sprague-Dawley; Stereoisomerism; Ventral Tegmental Area

1995
Stimulation of CRH-mediated ACTH secretion by central administration of neurotensin: evidence for the participation of the paraventricular nucleus.
    Journal of neuroendocrinology, 1995, Volume: 7, Issue:2

    Topics: Adrenocorticotropic Hormone; Animals; Body Temperature Regulation; Corticotropin-Releasing Hormone; Hypothalamo-Hypophyseal System; Injections, Intraventricular; Male; Median Eminence; Neurotensin; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Pituitary-Adrenal System; Protein Structure, Secondary; Pyrrolidonecarboxylic Acid; Rats; Stimulation, Chemical

1995
Potencies of various neurotensin-(8-13) analogs for inhibition of heat-induced edema in the anesthetized rat.
    Regulatory peptides, 1995, Mar-07, Volume: 56, Issue:1

    Topics: Amino Acid Sequence; Anesthesia; Animals; Blood Pressure; Edema; Gastrointestinal Motility; Hot Temperature; Hypotension; Male; Molecular Sequence Data; Neurotensin; Oligopeptides; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley; Xenopus Proteins

1995
Strong effects of NT/NN peptides on DA D2 receptors in rat neostriatal sections.
    Neuroreport, 1994, Aug-15, Volume: 5, Issue:13

    Topics: Animals; Autoradiography; Binding, Competitive; In Vitro Techniques; Male; Neostriatum; Neuropeptides; Neurotensin; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Neurotensin

1994
The non-peptide neurotensin receptor antagonist SR48692 is not a potent antagonist of neurotensin(8-13) responses of rat substantia nigra neurones in vitro.
    Neuroscience letters, 1994, May-19, Volume: 172, Issue:1-2

    Topics: Action Potentials; Animals; Dopamine; Electrophysiology; In Vitro Techniques; Male; Neurons; Neurotensin; Peptide Fragments; Pyrazoles; Quinolines; Rats; Receptors, Neurotensin; Substantia Nigra

1994
Mesencephalic microinjections of neurotensin-(1-13) and its C-terminal fragment, neurotensin-(8-13), potentiate brain stimulation reward.
    Brain research, 1993, Jul-09, Volume: 616, Issue:1-2

    Topics: Animals; Brain; Brain Mapping; Conditioning, Operant; Electric Stimulation; Mesencephalon; Microinjections; Neurotensin; Neurotransmitter Uptake Inhibitors; Peptide Fragments; Piperazines; Rats; Reward; Sensory Thresholds

1993
The C-terminal neurotensin-(8-13) fragment potently modulates rat neostriatal dopamine D2 receptors.
    European journal of pharmacology, 1993, Mar-30, Volume: 234, Issue:1

    Topics: Animals; Binding, Competitive; In Vitro Techniques; Male; Neostriatum; Neurotensin; Peptide Fragments; Raclopride; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Salicylamides

1993
Xenopsin, neurotensin, neurotensin(8-13) and N-acetyl-neurotensin(8-13) inhibit vascular leakage in rats after tissue injury.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:2

    Topics: Animals; Brain Edema; Capillary Permeability; Edema; Hot Temperature; Male; Muscles; Neurotensin; Oligopeptides; Peptide Fragments; Peptides; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Xenopus Proteins

1993
Proposed ligand binding site of the transmembrane receptor for neurotensin(8-13).
    The Journal of biological chemistry, 1996, Jun-21, Volume: 271, Issue:25

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cell Membrane; CHO Cells; Computer Graphics; Cricetinae; DNA Primers; Humans; Ligands; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Neurotensin; Peptide Fragments; Phosphatidylinositols; Point Mutation; Polymerase Chain Reaction; Protein Structure, Secondary; Radioligand Assay; Rats; Receptors, Neurotensin; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Transfection

1996
Effects of neurotensin on neurons in the rat central amygdaloid nucleus in vitro.
    Brain research bulletin, 1996, Volume: 40, Issue:2

    Topics: Amygdala; Animals; Brain Mapping; In Vitro Techniques; Male; Neurons; Neurotensin; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar

1996
Release of calcitonin gene-related peptide in guinea pig inferior mesenteric ganglion.
    Peptides, 1996, Volume: 17, Issue:1

    Topics: Afferent Pathways; Animals; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Colon; Enkephalin, Leucine; Enkephalin, Methionine; Ganglia; Guinea Pigs; In Vitro Techniques; Magnesium; Male; Mesentery; Nerve Endings; Neurotensin; Peptide Fragments; Potassium

1996
Differential effects of intrastriatal neurotensin(1-13) and neurotensin(8-13) on striatal dopamine and pallidal GABA release. A dual-probe microdialysis study in the awake rat.
    The European journal of neuroscience, 1997, Volume: 9, Issue:9

    Topics: Animals; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Globus Pallidus; Male; Microdialysis; Neurotensin; Peptide Fragments; Perfusion; Pergolide; Pyrazoles; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin

1997
In vitro binding and CNS effects of novel neurotensin agonists that cross the blood-brain barrier.
    Neuropharmacology, 1999, Volume: 38, Issue:7

    Topics: Animals; Binding Sites; Blood-Brain Barrier; Central Nervous System; Humans; Male; Neurotensin; Peptide Fragments; Rats; Rats, Sprague-Dawley

1999
Synthesis and human neurotensin receptor binding activities of neurotensin(8-13) analogues containing position 8 alpha-azido-N-alkylated derivatives of ornithine, lysine, and homolysine.
    Journal of medicinal chemistry, 1999, Nov-18, Volume: 42, Issue:23

    Topics: Animals; Azides; CHO Cells; Cricetinae; Humans; Lysine; Neurotensin; Ornithine; Peptide Fragments; Radioligand Assay; Receptors, Neurotensin; Structure-Activity Relationship

1999
Neurotensin attenuates the quinpirole-induced inhibition of the firing rate of dopamine neurons in the rat substantia nigra pars compacta and the ventral tegmental area.
    Neuroscience, 2000, Volume: 95, Issue:2

    Topics: Action Potentials; Adamantane; Animals; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Electrophysiology; Imidazoles; In Vitro Techniques; Logistic Models; Male; Neurons; Neurotensin; Peptide Fragments; Quinpirole; Rats; Rats, Wistar; Receptors, Neurotensin; Substantia Nigra; Ventral Tegmental Area

2000
Highly potent neurotensin analog that causes hypothermia and antinociception.
    European journal of pharmacology, 2000, Feb-25, Volume: 390, Issue:1-2

    Topics: Analgesics; Animals; Body Temperature; Dose-Response Relationship, Drug; Hypothermia; Injections, Intraperitoneal; Male; Neurotensin; Pain Measurement; Peptide Fragments; Rats; Rats, Sprague-Dawley

2000
Neurotensin regulates intracellular calcium in ventral tegmental area astrocytes: evidence for the involvement of multiple receptors.
    Neuroscience, 2000, Volume: 97, Issue:2

    Topics: Adamantane; Animals; Animals, Newborn; Astrocytes; Calcium; Cells, Cultured; Estrenes; Gadolinium; Imidazoles; Neurotensin; Peptide Fragments; Piperidines; Pyrrolidinones; Rats; Receptors, Neurotensin; Thapsigargin; Type C Phospholipases; Ventral Tegmental Area

2000
Comparative effects of neurotensin, neurotensin(8-13) and [D-Tyr(11)]neurotensin applied into the ventral tegmental area on extracellular dopamine in the rat prefrontal cortex and nucleus accumbens.
    Neuroscience, 2000, Volume: 98, Issue:3

    Topics: Animals; Dopamine; Electrochemistry; Extracellular Space; Male; Microinjections; Neurotensin; Nucleus Accumbens; Peptide Fragments; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Ventral Tegmental Area

2000
A single amino acid of the human and rat neurotensin receptors (subtype 1) determining the pharmacological profile of a species-selective neurotensin agonist.
    Biochemical pharmacology, 2000, Sep-15, Volume: 60, Issue:6

    Topics: Amino Acid Substitution; Animals; Cells, Cultured; CHO Cells; Cricetinae; Humans; Mutagenesis, Site-Directed; Neurotensin; Peptide Fragments; Radioligand Assay; Rats; Receptors, Neurotensin; Transfection

2000
Effects of prefrontal cortex microinjection of neurotensin-(8-13) on midbrain dopamine and non-dopamine cell firing.
    Brain research, 2000, Sep-08, Volume: 876, Issue:1-2

    Topics: Action Potentials; Animals; Dopamine; Dose-Response Relationship, Drug; Male; Mesencephalon; Microinjections; Neurons; Neurotensin; Peptide Fragments; Prefrontal Cortex; Rats; Rats, Long-Evans; Time Factors

2000
Neurotensin modulates the electrical activity of frog pituitary melanotropes via activation of a G-protein-coupled receptor pharmacologically related to both the NTS1 and nts2 receptors of mammals.
    Neuroendocrinology, 2000, Volume: 72, Issue:6

    Topics: Adamantane; Animals; Cells, Cultured; GTP-Binding Protein alpha Subunits, Gq-G11; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Heterotrimeric GTP-Binding Proteins; Imidazoles; Ligands; Male; Mammals; Melanocytes; Membrane Potentials; Neurotensin; Patch-Clamp Techniques; Peptide Fragments; Pituitary Gland; Pyrazoles; Quinolines; Rana ridibunda; Receptors, Neurotensin; Signal Transduction; Thionucleotides

2000
In vitro and in vivo evaluation of new radiolabeled neurotensin(8-13) analogues with high affinity for NT1 receptors.
    Nuclear medicine and biology, 2001, Volume: 28, Issue:1

    Topics: Animals; Chromatography, High Pressure Liquid; Drug Stability; Half-Life; HT29 Cells; Humans; Mice; Mice, Nude; Neurotensin; Peptide Fragments; Radiopharmaceuticals; Receptors, Neurotensin; Structure-Activity Relationship; Tissue Distribution

2001
Biodistribution and catabolism of (18)F-labeled neurotensin(8-13) analogs.
    Nuclear medicine and biology, 2002, Volume: 29, Issue:1

    Topics: Animals; Autoradiography; Binding, Competitive; Calcium; Fluorine Radioisotopes; Half-Life; HT29 Cells; Humans; Metabolic Clearance Rate; Mice; Neurotensin; Peptide Fragments; Radiochemistry; Rats; Rats, Wistar; Receptors, Neurotensin; Structure-Activity Relationship; Tissue Distribution

2002
Preclinical evaluation of a new, stabilized neurotensin(8--13) pseudopeptide radiolabeled with (99m)tc.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2002, Volume: 43, Issue:3

    Topics: Adenocarcinoma; Animals; Female; HT29 Cells; Humans; In Vitro Techniques; Mice; Mice, Nude; Neoplasm Transplantation; Neurotensin; Peptide Fragments; Radionuclide Imaging; Radiopharmaceuticals; Receptors, Neurotensin; Structure-Activity Relationship; Technetium; Tissue Distribution

2002
Influence of silaproline on peptide conformation and bioactivity.
    Journal of the American Chemical Society, 2002, Mar-27, Volume: 124, Issue:12

    Topics: Animals; Cell Membrane; COS Cells; Crystallography, X-Ray; Models, Molecular; Neurotensin; Nuclear Magnetic Resonance, Biomolecular; Organosilicon Compounds; Peptide Fragments; Proline; Protein Conformation; Stereoisomerism

2002
Topography of the neurotensin (NT)(8-9) binding site of human NT receptor-1 probed with NT(8-13) analogs.
    The journal of peptide research : official journal of the American Peptide Society, 2002, Volume: 59, Issue:2

    Topics: Amino Acid Substitution; Amino Acids; Animals; Arginine; Binding Sites; CHO Cells; Cricetinae; Humans; Kinetics; Neurotensin; Peptide Fragments; Radioligand Assay; Receptors, Neurotensin; Recombinant Proteins; Transfection

2002
Presynaptic action of neurotensin on cultured ventral tegmental area dopaminergic neurones.
    Neuroscience, 2002, Volume: 111, Issue:1

    Topics: Animals; Cells, Cultured; Dopamine; Excitatory Postsynaptic Potentials; Membrane Potentials; Neurons; Neurotensin; Patch-Clamp Techniques; Peptide Fragments; Presynaptic Terminals; Rats; Receptors, Neurotensin; Tegmentum Mesencephali; Time Factors

2002
Probing the environment of neurotensin whilst bound to the neurotensin receptor by solid state NMR.
    FEBS letters, 2002, May-08, Volume: 518, Issue:1-3

    Topics: Animals; Binding Sites; Neurotensin; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Protein Conformation; Rats; Receptors, Neurotensin; Sensitivity and Specificity; Structure-Activity Relationship

2002
The neurotensin fragment AcNT(8-13) inhibits lowering of interstitial fluid pressure in rat trachea.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:3

    Topics: Albumins; Animals; Anti-Inflammatory Agents; Blood Pressure; Capillary Permeability; Edema; Extracellular Space; Female; Hydrostatic Pressure; Iodine Radioisotopes; Neurotensin; Peptide Fragments; Rats; Rats, Wistar; Trachea; Water

2002
Monitoring neurotensin[8-13] degradation in human and rat serum utilizing matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
    Analytical biochemistry, 2002, Sep-01, Volume: 308, Issue:1

    Topics: Amino Acid Sequence; Animals; Azides; Calibration; Half-Life; Humans; Molecular Weight; Neurotensin; Peptide Fragments; Protein Binding; Rats; Receptors, Neurotensin; Reference Standards; Regression Analysis; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors

2002
Synthesis and biological studies of novel neurotensin(8-13) mimetics.
    Bioorganic & medicinal chemistry, 2002, Volume: 10, Issue:12

    Topics: Animals; Humans; Indoles; Molecular Mimicry; Neurotensin; Peptide Fragments; Radioligand Assay; Rats; Receptors, Neurotensin; Structure-Activity Relationship

2002
Prolyl endopeptidase inhibitory peptides in wine.
    Bioscience, biotechnology, and biochemistry, 2003, Volume: 67, Issue:2

    Topics: Amino Acid Sequence; Inhibitory Concentration 50; Neurotensin; Peptide Fragments; Peptides; Prolyl Oligopeptidases; Serine Endopeptidases; Serine Proteinase Inhibitors; Substance P; Vasopressins; Vitis; Wine

2003
In vitro analysis of stable, receptor-selective neurotensin[8-13] analogues.
    Journal of medicinal chemistry, 2003, Sep-11, Volume: 46, Issue:19

    Topics: Amino Acid Sequence; Amino Acids; Animals; COS Cells; Drug Stability; Half-Life; Humans; Neurotensin; Peptide Fragments; Phosphatidylinositols; Rats; Receptors, Neurotensin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Transfection

2003
Gq/11-induced and spontaneous waves of coordinated network activation in developing frontal cortex.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Feb-16, Volume: 25, Issue:7

    Topics: Acetylcholine; Action Potentials; Animals; Benzazepines; Calcium Signaling; Dopamine; Frontal Lobe; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gq-G11; Indans; Muscarine; Nerve Tissue Proteins; Neurotensin; Occipital Lobe; Parietal Lobe; Peptide Fragments; Phenanthridines; Picrotoxin; Rats; Rats, Long-Evans; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Receptors, Dopamine D1; Receptors, Metabotropic Glutamate

2005
In vivo behavioral effects of stable, receptor-selective neurotensin[8-13] analogues that cross the blood-brain barrier.
    Neuropharmacology, 2005, Volume: 48, Issue:3

    Topics: Animals; Blood-Brain Barrier; Dose-Response Relationship, Drug; Hypothermia; Male; Motor Activity; Neurotensin; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin

2005
Design, synthesis, and evaluation of the antipsychotic potential of orally bioavailable neurotensin (8-13) analogues containing non-natural arginine and lysine residues.
    Neuropharmacology, 2005, Volume: 49, Issue:8

    Topics: Animals; Antipsychotic Agents; Area Under Curve; Arginine; Biological Availability; Catalepsy; Central Nervous System Stimulants; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Design; Haloperidol; Injections, Intraperitoneal; Lysine; Male; Motor Activity; Neurotensin; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin

2005
Novel 99mTc-labeled neurotensin analogues with optimized biodistribution properties.
    Journal of medicinal chemistry, 2006, Mar-09, Volume: 49, Issue:5

    Topics: Animals; Chelating Agents; Drug Stability; Humans; In Vitro Techniques; Mice; Mice, Nude; Neoplasm Transplantation; Neurotensin; Oligopeptides; Organotechnetium Compounds; Peptide Fragments; Plasma; Radiopharmaceuticals; Shikimic Acid; Structure-Activity Relationship; Tissue Distribution; Transplantation, Heterologous

2006
Radionuclide imaging of small-cell lung cancer (SCLC) using 99mTc-labeled neurotensin peptide 8-13.
    Nuclear medicine and biology, 2006, Volume: 33, Issue:4

    Topics: Animals; Biomarkers, Tumor; Carcinoma, Small Cell; Cell Line, Tumor; Feasibility Studies; Female; Humans; Isotope Labeling; Metabolic Clearance Rate; Mice; Mice, Nude; Neoplasm Proteins; Neurotensin; Organ Specificity; Peptide Fragments; Radionuclide Imaging; Radiopharmaceuticals; Receptors, Neurotensin; Technetium; Tissue Distribution

2006
Synthesis and evaluation of novel multimeric neurotensin(8-13) analogs.
    Bioorganic & medicinal chemistry, 2006, Sep-01, Volume: 14, Issue:17

    Topics: Amino Acid Sequence; HT29 Cells; Humans; Inhibitory Concentration 50; Neurotensin; Peptide Fragments; Protein Binding; Receptors, Neurotensin

2006
Radiolabeling of multimeric neurotensin(8-13) analogs with the short-lived positron emitter fluorine-18.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2007, Volume: 65, Issue:7

    Topics: Benzaldehydes; Benzoates; Dimerization; Electrons; Fluorine Radioisotopes; Isotope Labeling; Maleimides; Neurotensin; Peptide Fragments; Succinimides

2007
Neurotensin in the ventral pallidum increases extracellular gamma-aminobutyric acid and differentially affects cue- and cocaine-primed reinstatement.
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 325, Issue:2

    Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; gamma-Aminobutyric Acid; Male; Motor Activity; Neurotensin; Peptide Fragments; Pyrazoles; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin; Self Administration

2008
Separation and determination of peptide hormones by capillary electrophoresis with laser-induced fluorescence coupled with transient pseudo-isotachophoresis preconcentration.
    Analytical biochemistry, 2008, Sep-15, Volume: 380, Issue:2

    Topics: Cell Adhesion Molecules; Electrophoresis, Capillary; Fluorescein-5-isothiocyanate; Fluorescence; Humans; Lasers, Gas; Neurokinin B; Neurotensin; Peptide Fragments; Peptide Hormones; Receptor Protein-Tyrosine Kinases; Subarachnoid Hemorrhage

2008
Comparison of N-terminal modifications on neurotensin(8-13) analogues correlates peptide stability but not binding affinity with in vivo efficacy.
    Journal of medicinal chemistry, 2009, Apr-09, Volume: 52, Issue:7

    Topics: Aminopeptidases; Animals; Binding, Competitive; Body Temperature; Calcium; Cell Line; Humans; In Vitro Techniques; Intracellular Space; Male; Neurotensin; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin; Structure-Activity Relationship

2009
Synthesis of neurotensin(8-13)-phosphopeptide heterodimers via click chemistry.
    Bioorganic & medicinal chemistry letters, 2010, Jun-01, Volume: 20, Issue:11

    Topics: Chromatography, High Pressure Liquid; Dimerization; Neurotensin; Peptide Fragments; Phosphopeptides

2010
Identification and functional characterization of a stable, centrally active derivative of the neurotensin (8-13) fragment as a potential first-in-class analgesic.
    Journal of medicinal chemistry, 2010, Jun-24, Volume: 53, Issue:12

    Topics: Analgesics; Animals; Binding, Competitive; Body Temperature; Calcium; Cell Line; Drug Tolerance; Humans; Male; Neurotensin; Oligopeptides; Pain Measurement; Peptide Fragments; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin; Structure-Activity Relationship

2010
Neurotensin(8-13) analogue: radiolabeling and biological evaluation using different chelators.
    Nuclear medicine and biology, 2011, Volume: 38, Issue:1

    Topics: Animals; Blood Proteins; Chelating Agents; Cross-Linking Reagents; Cysteine; Drug Stability; Female; Glutathione; Hydrazines; Isotope Labeling; Mice; Neurotensin; Nicotinic Acids; Oligopeptides; Organotechnetium Compounds; Peptide Fragments; Radiochemistry; Succinimides

2011
Target-selective drug delivery through liposomes labeled with oligobranched neurotensin peptides.
    ChemMedChem, 2011, Apr-04, Volume: 6, Issue:4

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Adenocarcinoma; Antineoplastic Agents; Colonic Neoplasms; Drug Delivery Systems; Humans; Hydrodynamics; Liposomes; Lysine; Neurotensin; Peptide Fragments; Rhabdomyosarcoma; Tumor Cells, Cultured

2011
Solid-phase extraction-field-amplified sample injection coupled with CE-ESI-MS for online pre-concentration and quantitative analysis of brain-gut peptides.
    Electrophoresis, 2011, Volume: 32, Issue:20

    Topics: Electrophoresis, Capillary; Humans; Limit of Detection; Neurotensin; Peptide Fragments; Regression Analysis; Reproducibility of Results; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Tetragastrin

2011
[Neurotensin NT (8- 13) dipeptide analog dilept increases the pain threshold and decreases the severity of morphine withdrawal syndrome in rats].
    Eksperimental'naia i klinicheskaia farmakologiia, 2013, Volume: 76, Issue:10

    Topics: Animals; Dopamine; Frontal Lobe; Hypothalamus; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Neurotensin; Pain; Pain Threshold; Peptide Fragments; Proline; Rats; Serotonin; Severity of Illness Index; Substance Withdrawal Syndrome; Tyrosine

2013
Neurotensin Induces Presynaptic Depression of D2 Dopamine Autoreceptor-Mediated Neurotransmission in Midbrain Dopaminergic Neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Aug-05, Volume: 35, Issue:31

    Topics: Animals; Calcineurin; Dopaminergic Neurons; Male; Mesencephalon; Mice; Mice, Inbred DBA; Neurotensin; Peptide Fragments; Presynaptic Terminals; Receptors, Dopamine D2; Receptors, Neurotensin; Signal Transduction; Synaptic Transmission

2015
1,2,3-Triazole Stabilized Neurotensin-Based Radiopeptidomimetics for Improved Tumor Targeting.
    Bioconjugate chemistry, 2015, Oct-21, Volume: 26, Issue:10

    Topics: Animals; Antineoplastic Agents; Chemistry Techniques, Synthetic; Cycloaddition Reaction; Female; Half-Life; HT29 Cells; Humans; Isotope Labeling; Lutetium; Mice, Nude; Molecular Targeted Therapy; Neurotensin; Peptide Fragments; Peptidomimetics; Radioisotopes; Receptors, Neurotensin; Structure-Activity Relationship; Tissue Distribution; Triazoles; Xenograft Model Antitumor Assays

2015
Mimicking of Arginine by Functionalized N(ω)-Carbamoylated Arginine As a New Broadly Applicable Approach to Labeled Bioactive Peptides: High Affinity Angiotensin, Neuropeptide Y, Neuropeptide FF, and Neurotensin Receptor Ligands As Examples.
    Journal of medicinal chemistry, 2016, Mar-10, Volume: 59, Issue:5

    Topics: Angiotensin II; Arginine; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Ligands; Molecular Structure; Neuropeptide Y; Neurotensin; Oligopeptides; Peptide Fragments; Receptors, Angiotensin; Receptors, Neuropeptide; Receptors, Neurotensin; Structure-Activity Relationship

2016
Neurotensin-based hybrid peptide's anti-inflammatory activity in murine model of a contact sensitivity response.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2016, Oct-10, Volume: 93

    Topics: Animals; Anti-Inflammatory Agents; Cytokines; Dermatitis, Contact; Disease Models, Animal; Female; Male; Mice; Neurotensin; Peptide Fragments

2016
Structural Optimization and Characterization of Potent Analgesic Macrocyclic Analogues of Neurotensin (8-13).
    Journal of medicinal chemistry, 2018, 08-23, Volume: 61, Issue:16

    Topics: Analgesics, Non-Narcotic; Animals; Binding, Competitive; Blood Pressure; Body Temperature; CHO Cells; Cricetulus; Cyclization; Drug Evaluation, Preclinical; Drug Stability; Male; Molecular Docking Simulation; Neurotensin; Peptide Fragments; Peptides, Cyclic; Rats, Sprague-Dawley; Receptors, Neurotensin; Structure-Activity Relationship; Tyrosine

2018
The combination of opioid and neurotensin receptor agonists improves their analgesic/adverse effect ratio.
    European journal of pharmacology, 2019, Apr-05, Volume: 848

    Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Therapy, Combination; Male; Morphine; Neurotensin; Pain Measurement; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin; Receptors, Opioid, mu

2019