neuropeptide-y and arginylphenylalaninamide

neuropeptide-y has been researched along with arginylphenylalaninamide* in 2 studies

Other Studies

2 other study(ies) available for neuropeptide-y and arginylphenylalaninamide

Article	Year
Diet-induced adaptive thermogenesis requires neuropeptide FF receptor-2 signalling. Nature communications, 2018, 11-09, Volume: 9, Issue:1 Excess caloric intake results in increased fat accumulation and an increase in energy expenditure via diet-induced adaptive thermogenesis; however, the underlying mechanisms controlling these processes are unclear. Here we identify the neuropeptide FF receptor-2 (NPFFR2) as a critical regulator of diet-induced thermogenesis and bone homoeostasis. Npffr2 Topics: Adipose Tissue, Brown; Animals; Arcuate Nucleus of Hypothalamus; Behavior, Animal; Bone and Bones; Cold Temperature; Diet; Energy Metabolism; Female; Homeostasis; Ligands; Male; Mice, Knockout; Neurons; Neuropeptide Y; Neuropeptides; Osteogenesis; Receptors, Neuropeptide; RNA, Messenger; Signal Transduction; Thermogenesis	2018
Coordinated regulation of foraging and metabolism in C. elegans by RFamide neuropeptide signaling. Cell metabolism, 2009, Volume: 9, Issue:4 Animals modify food-seeking behavior and metabolism according to perceived food availability. Here we show that, in the roundworm C. elegans, release of neuropeptides from interneurons that are directly postsynaptic to olfactory, gustatory, and thermosensory neurons coordinately regulates behavior and metabolism. Animals lacking these neuropeptides, encoded by the flp-18 gene, are defective in chemosensation and foraging, accumulate excess fat, and exhibit reduced oxygen consumption. Two G protein-coupled receptors of the NPY/RFamide family, NPR-4 and NPR-5, are activated by FLP-18 peptides in vitro and exhibit mutant phenotypes that recapitulate those of flp-18 mutants. Our data suggest that sensory input can coordinately regulate behavior and metabolism via NPY/RFamide-like receptors. They suggest that peptidergic feedback from interneurons regulates sensory neuron activity, and that at least some of this communication occurs extrasynaptically. Extrasynaptic neuropeptide signaling may greatly increase the computational capacity of neural circuits. Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Feeding Behavior; Interneurons; Intestinal Mucosa; Intestines; Lipid Metabolism; Models, Biological; Mutation; Neuropeptide Y; Neuropeptides; Odorants; Organ Specificity; Peptides; Phenotype; Receptors, Cell Surface; Signal Transduction; Xenopus	2009

Article

Year

Diet-induced adaptive thermogenesis requires neuropeptide FF receptor-2 signalling.

Nature communications, 2018, 11-09, Volume: 9, Issue:1

Excess caloric intake results in increased fat accumulation and an increase in energy expenditure via diet-induced adaptive thermogenesis; however, the underlying mechanisms controlling these processes are unclear. Here we identify the neuropeptide FF receptor-2 (NPFFR2) as a critical regulator of diet-induced thermogenesis and bone homoeostasis. Npffr2

Topics: Adipose Tissue, Brown; Animals; Arcuate Nucleus of Hypothalamus; Behavior, Animal; Bone and Bones; Cold Temperature; Diet; Energy Metabolism; Female; Homeostasis; Ligands; Male; Mice, Knockout; Neurons; Neuropeptide Y; Neuropeptides; Osteogenesis; Receptors, Neuropeptide; RNA, Messenger; Signal Transduction; Thermogenesis

2018

Coordinated regulation of foraging and metabolism in C. elegans by RFamide neuropeptide signaling.

Cell metabolism, 2009, Volume: 9, Issue:4

Animals modify food-seeking behavior and metabolism according to perceived food availability. Here we show that, in the roundworm C. elegans, release of neuropeptides from interneurons that are directly postsynaptic to olfactory, gustatory, and thermosensory neurons coordinately regulates behavior and metabolism. Animals lacking these neuropeptides, encoded by the flp-18 gene, are defective in chemosensation and foraging, accumulate excess fat, and exhibit reduced oxygen consumption. Two G protein-coupled receptors of the NPY/RFamide family, NPR-4 and NPR-5, are activated by FLP-18 peptides in vitro and exhibit mutant phenotypes that recapitulate those of flp-18 mutants. Our data suggest that sensory input can coordinately regulate behavior and metabolism via NPY/RFamide-like receptors. They suggest that peptidergic feedback from interneurons regulates sensory neuron activity, and that at least some of this communication occurs extrasynaptically. Extrasynaptic neuropeptide signaling may greatly increase the computational capacity of neural circuits.

Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Feeding Behavior; Interneurons; Intestinal Mucosa; Intestines; Lipid Metabolism; Models, Biological; Mutation; Neuropeptide Y; Neuropeptides; Odorants; Organ Specificity; Peptides; Phenotype; Receptors, Cell Surface; Signal Transduction; Xenopus

2009